Anti-aging repairing essence as well as preparation method and application thereof

Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to anti-aging repairing essence as well as a preparation method and application thereof. The anti-aging repairing essence is prepared from the following components in parts by weight: 5 to 55 parts of blue algae extract, 0.08 to 1.3 parts of turmeric root extract, 0.1 to 1 part of carnosine, 0.05 to 0.5 part of spirulina maxima extract, 0.01 to 0.2 part of hydrolyzed sodium hyaluronate, 0.01 to 0.2 part of ergothioneine and 0.005 to 0.15 part of acetyl hexapeptide-8. According to the anti-aging repairing essence provided by the invention, various natural extracts and active ingredients are carefully selected and proportioned, so that the essence shows excellent effects of moisturizing, nourishing, repairing damaged skin, improving skin compactness, resisting aging, repairing and the like, has good skin affinity and tenderness, and is suitable for being used by various skin types.

Description

Technical Field

[0001] The present invention belongs to the technical field of cosmetics, and in particular relates to an anti-aging and repairing essence, a preparation method and an application thereof. Background Art

[0002] With increasing age and the influence of external environmental factors, skin aging has become a significant problem for people. Key manifestations of skin aging include fine lines, wrinkles, sagging skin, and dark spots, all of which severely impact a person's appearance and self-confidence. A wide variety of anti-aging products are currently available, with anti-aging serums being a key component. However, most existing anti-aging serums still have certain limitations in their effectiveness, failing to meet consumers' comprehensive demands for skin repair and anti-aging benefits.

[0003] While many existing anti-aging serums can provide short-term moisturization and firming, they still fall short of addressing deeper skin aging issues, such as skin cell repair, collagen loss, and free radical scavenging. Some serums may contain ingredients that are highly irritating to the skin, potentially causing allergies or discomfort with prolonged use. Furthermore, many existing products on the market lack effective formulas and ingredient combinations, resulting in limited anti-aging effects and an inability to maintain sustained improvements over time.

[0004] Therefore, there is an urgent need for a new anti-aging and repairing essence that can act on the skin's aging problems from multiple dimensions, provide deep repair, and effectively promote the skin's self-repair to achieve a more lasting and significant anti-aging effect, while ensuring that the ingredients are safe and gentle and suitable for all skin types. Summary of the Invention

[0005] The purpose of the present invention is to overcome the deficiencies of the above-mentioned prior art and to provide an anti-aging repair essence and a preparation method and application thereof.

[0006] To achieve the above objectives, the technical solutions adopted by the present invention include:

[0007] In a first aspect, the present invention provides an anti-aging repair essence, which comprises the following components in parts by weight: 5-55 parts of cyanobacteria extract, 0.08-1.3 parts of turmeric root extract, 0.1-1 parts of carnosine, 0.05-0.5 parts of Spirulina maxima extract, 0.01-0.2 parts of hydrolyzed sodium hyaluronate, 0.01-0.2 parts of ergothioneine and 0.005-0.15 parts of acetyl hexapeptide-8.

[0008] The anti-aging and repairing essence provided by the present invention exhibits excellent moisturizing and nourishing, repairing damaged skin, improving skin firmness and anti-aging repair effects through the careful selection and proportioning of multiple natural extracts and active ingredients. Among them, cyanobacteria extract is rich in various minerals, vitamins and amino acids, and has moisturizing, anti-oxidation, anti-inflammatory and cell regeneration functions, and helps enhance the skin's barrier function and improve skin elasticity; curcumin, the active ingredient in turmeric root extract, can help slow down the skin aging process and promote the self-repair of skin cells; carnosine, as a small molecule peptide, can accelerate the repair and regeneration of skin cells and effectively improve the skin's resistance to stress; Spirulina extract is rich in plant protein, amino acids and minerals, which can promote deep repair and regeneration of the skin; hydrolyzed sodium hyaluronate can penetrate deeper into the skin, provide long-lasting moisturizing effects, and reduce the appearance of wrinkles and fine lines; ergothioneine has good anti-aging effects, can effectively inhibit the generation of free radicals, and promote skin metabolism and repair; acetyl hexapeptide-8 is an effective ingredient that reduces fine lines and wrinkles by inhibiting facial muscle contraction, which can promote skin smoothness and firmness, and achieve gradual improvement with long-term use.

[0009] After a large number of experiments and investigations, it was found that by compounding the above-mentioned active ingredients to prepare the essence, the components cooperate with each other, and can work together in many aspects such as anti-aging repair, skin cell repair, anti-oxidation, reducing fine lines and improving skin firmness, thereby significantly improving the youthful state of the skin. In particular, there is an obvious synergistic effect between cyanobacteria extract, turmeric root extract, spirulina extract and ergothioneine, which can significantly improve the anti-aging and repair effect of the essence while synergistically enhancing the stability of ergothioneine to avoid its degradation or failure during use, thereby improving the overall effect and durability of the product.

[0010] In addition, the inventors explored the dosage of each component and found that when the dosage ratio of cyanobacteria extract, turmeric root extract, spirulina maxima extract and ergothioneine exceeded the specified range of the present invention, the synergistic effect between the components was not obvious or even produced an antagonistic effect, thereby resulting in a decrease in the anti-aging and repair effect of the essence, indicating that the above four components have an ideal synergistic effect within the preferred range of the present invention.

[0011] Preferably, the anti-aging repair essence comprises the following components in parts by weight: 20-50 parts of cyanobacteria extract, 0.15-0.9 parts of turmeric root extract, 0.2-0.5 parts of carnosine, 0.08-0.3 parts of Spirulina maxima extract, 0.05-0.12 parts of hydrolyzed sodium hyaluronate, 0.05-0.12 parts of ergothioneine and 0.01-0.1 parts of acetyl hexapeptide-8.

[0012] Preferably, the anti-aging repair essence comprises the following components in parts by weight: 30 parts of cyanobacteria extract, 0.5 parts of turmeric root extract, 0.3 parts of carnosine, 0.15 parts of Spirulina maxima extract, 0.1 parts of hydrolyzed sodium hyaluronate, 0.1 parts of ergothioneine and 0.08 parts of acetyl hexapeptide-8.

[0013] Experimental investigations have revealed that when the components of the present invention are combined in the optimal dosage ratios defined above, their respective functions can be maximized, ensuring the best effects of the prepared essence in terms of anti-aging, repair and stability.

[0014] Preferably, the anti-aging repair essence further comprises the following components in parts by weight: 0.8-15.5 parts of moisturizing agent, 0.06-1.2 parts of thickening agent, 0.005-0.1 parts of chelating agent and 0.1-0.8 parts of preservative.

[0015] Preferably, the anti-aging repair essence further comprises the following components in parts by weight: 1.9-9.5 parts of moisturizer, 0.15-0.85 parts of thickener, 0.01-0.05 parts of chelating agent and 0.17-0.65 parts of preservative.

[0016] More preferably, the anti-aging repair essence further comprises the following components in parts by weight: 5.5 parts of moisturizer, 0.5 parts of thickener, 0.03 parts of chelating agent and 0.42 parts of preservative.

[0017] Preferably, the moisturizing agent comprises at least one of butylene glycol, polyglycerol-10, 1,2-hexanediol, caprylyl glycol and lactobacillus fermentation product.

[0018] Preferably, the thickener includes at least one of ammonium acryloyldimethyltaurate / VP copolymer and sodium polyacryloyldimethyltaurate.

[0019] Preferably, the chelating agent comprises disodium EDTA.

[0020] Preferably, the preservative includes at least one of p-hydroxyacetophenone, phenoxyethanol and ethylhexylglycerin.

[0021] In a second aspect, the present invention provides the use of the anti-aging repair essence in cosmetics.

[0022] In a third aspect, the present invention provides a method for preparing the anti-aging repair essence, comprising the following steps:

[0023] S1. Stir and mix the moisturizer, thickener, and chelating agent, homogenize at 82-85° C. for 3-7 minutes until completely dissolved, and keep warm for 15-25 minutes to obtain mixture A;

[0024] S2. Cooling the mixture A to 55-60° C., adding the cyanobacteria extract and the preservative, and stirring under vacuum to obtain a mixture B;

[0025] S3. Cooling the mixture B to below 40° C., adding turmeric root extract, carnosine, Spirulina maxima extract, hydrolyzed sodium hyaluronate, ergothioneine and acetyl hexapeptide-8, and stirring for 15-25 minutes to obtain the anti-aging repair essence.

[0026] Compared with the prior art, the present invention has the following beneficial effects:

[0027] (1) The essence of the present invention forms a multi-dimensional anti-aging system by combining cyanobacteria extract with turmeric root extract, spirulina extract, ergothioneine and other ingredients. Each component can not only act on skin aging problems from different angles, but also achieve synergistic synergy, effectively enhance the repair effect, thereby improving the skin's self-repair ability and promoting the skin's firmness and elasticity recovery;

[0028] (2) thioneine, as a powerful anti-aging ingredient, synergizes with other components such as turmeric root extract and spirulina extract in the present invention, and can significantly improve the stability of thioneine. Therefore, the innovative formula of the present invention effectively avoids the problem that thioneine loses its effectiveness due to changes in the external environment during use, thereby enhancing the overall effect and persistence of the product;

[0029] (3) The essence of the present invention has good skin affinity and mildness, can effectively moisturize the skin and reduce the appearance of fine lines and wrinkles, and does not irritate the skin. It is suitable for use on various skin types, especially sensitive skin. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 This is a diagram showing the appearance of the anti-aging repair essence prepared in Example 1. DETAILED DESCRIPTION

[0031] To better illustrate the purpose, technical solutions and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments. Those skilled in the art should understand that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0032] Unless otherwise specified, all raw materials involved in the following examples and comparative examples are commercially available general materials.

[0033] Examples 1-5

[0034] Examples 1-5 provide an anti-aging repair essence, the formula of which is shown in Table 1 (total weight parts are 100 parts). The preparation method of the anti-aging repair essence comprises the following steps:

[0035] S1. Stir and mix the moisturizer, thickener, and chelating agent, homogenize at 82-85°C for 5 minutes until completely dissolved, and keep warm for 20 minutes to obtain mixture A;

[0036] S2. Cooling the mixture A to 55-60° C., adding the cyanobacteria extract and the preservative, and stirring under vacuum to obtain a mixture B;

[0037] S3. Cooling the mixture B to below 40° C., adding turmeric root extract, carnosine, Spirulina maxima extract, hydrolyzed sodium hyaluronate, ergothioneine and acetyl hexapeptide-8, and stirring for 20 minutes to obtain the anti-aging repair essence.

[0038] Table 1: Formula of the anti-aging repair essence described in Examples 1-5 (parts by weight)

[0039]

[0040]

[0041] Comparative Examples 1-7

[0042] Comparative Examples 1-7 provide an anti-aging repair essence, the formula of which is shown in Table 2 (total weight parts is 100 parts). The preparation method of the anti-aging repair essence is the same as that of the examples, the only difference being the formula.

[0043] Table 2 Formula of the anti-aging repair essence described in Comparative Examples 1-7 (parts by weight)

[0044]

[0045]

[0046] Comparative Example 8

[0047] This comparative example provides an anti-aging repair essence, which differs from Example 1 only in that an equal amount of red wolfberry extract is used to replace the turmeric root extract, and the other components and amounts remain unchanged.

[0048] Comparative Example 9

[0049] This comparative example provides an anti-aging repair essence, which differs from Example 1 only in that an equal amount of Chlorella vulgaris extract is used to replace the Spirulina maxima extract, and the other components and amounts remain unchanged.

[0050] Comparative Example 10

[0051] This comparative example provides an anti-aging repair essence, which differs from Example 1 only in that an equal amount of glutathione is used to replace ergothioneine, and the other components and amounts remain unchanged.

[0052] Effect Examples

[0053] 1. Safety testing:

[0054] The anti-aging repair essences prepared in Examples 1-5 and Comparative Examples 1-10 were used as samples to test their safety. The specific testing method is as follows:

[0055] Test population: 150 subjects with facial wrinkles, aged 35-55, were randomly divided into 15 groups of 10. All subjects met the selection criteria for human skin patch testing as specified in the "Technical Specifications for Safety of Cosmetics" (2015 edition).

[0056] Test method: The anti-aging repair essence prepared in Examples 1-5 and Comparative Examples 1-10 was used for a patch test. Qualified patch test equipment was selected and a closed patch test method was used. Approximately 0.020-0.025 ml of the test substance was placed in the patch tester. Medical tape was applied to the curved side of the subject's forearm. The test substance was lightly pressed with the palm of the hand to evenly apply it to the skin. The test substance patch tester was removed after 24 hours, and the skin reaction was observed 0.5, 24, and 48 hours after the removal of the test substance patch tester. The results were recorded according to the skin reaction grading standard in the "Technical Specifications for Safety of Cosmetics" (2015 edition).

[0057] The results of the human skin patch test showed that there was no positive reaction among 150 people. According to the "Technical Specifications for Safety of Cosmetics" (2015 edition), the test substance will not cause adverse skin reactions and the sample is safe and non-irritating.

[0058] 2. Human testing:

[0059] The 150 subjects with facial wrinkles selected above were randomly divided into 15 groups, with 10 subjects in each group. The anti-aging and repairing essences described in Examples 1-5 and Comparative Examples 1-10 were tested for their anti-aging and skin repair effects. After cleansing their faces in the morning and evening, the subjects were then tested for the anti-aging and repairing effects of the essences described in Examples 1-5 and Comparative Examples 1-10 until fully absorbed. After 28 consecutive days of use, the subjects were tested on the evening of the 28th day after cleansing their faces and then applied to their faces for testing.

[0060] (1) Changes in skin roughness

[0061] The Canfield VISIA7 skin analyzer was used to capture facial images of subjects before and after using the serum, and the images were analyzed using the skin image analysis software PIMIA. Skin roughness is an important indicator that objectively reflects skin condition and aging. Skin roughness intuitively displays the fineness and texture changes of the human skin surface. By counting the changes in the number of characteristic mutation points per unit area of the skin surface, it reflects a person's skin care regimen, indirectly indicates the skin's moisture retention, and can track the progress of cosmetic skincare treatments. Roughness variance, statistical texture, and texture dispersion parameters characterize the statistical results of characteristic mutation points per unit area and quantify the roughness of the facial skin. Skin roughness reduction rate = (initial value - test value) / initial value. The test results are averaged for each group. The specific results are shown in Table 3.

[0062] (2) Changes in skin elasticity

[0063] A multi-probe skin tester was used to test the subjects' faces before and after using the serum. Based on the principles of suction and tension, a constant negative pressure was applied vertically to the skin. The pressure was then removed and the change in skin displacement over a specified period of time was measured. A larger value indicates greater skin elasticity. The improvement in skin elasticity was calculated as (test value - initial value) / initial value. The test results were averaged for each group. The specific results are shown in Table 3.

[0064] (3) Changes in transepidermal water loss (TEWL)

[0065] Using the German CK Tewameter™ Hex skin tester, the transepidermal water loss (TEWL) of the subjects was measured before using the serum. This was recorded as the initial value. The TEWL was then measured again after 28 days of use, also recorded as the test value. Finally, the rate of change in TEWL was calculated. A greater rate of change indicates a better repair effect. Rate of change = (initial value - test value) / initial value. The test results were averaged for each group. The specific results are shown in Table 3.

[0066] Table 3

[0067]

[0068] As can be seen from the results in Table 3, the essences prepared in the examples of the present invention have good anti-aging and repairing effects, especially the essence described in Example 1 has the best anti-aging and repairing effect, can significantly improve the skin's self-repair ability, and promote the recovery of skin's firmness and elasticity. When one or more of the active ingredients of cyanobacteria extract, turmeric root extract, spirulina extract and ergothioneine were missing in comparative examples 1-5, the anti-aging and repairing effect of the prepared essence was significantly reduced compared with Example 1. When the amount ratio of the four ingredients described in comparative examples 6-7 exceeded the preferred range of the present invention, the effect of the essence in improving skin elasticity, roughness, etc. was also reduced. The above results show that the cyanobacteria extract, turmeric root extract, spirulina extract and ergothioneine selected by the present invention can play a good synergistic effect when matched within the specific dosage ratio range, thereby strengthening the multifunctional effect of the essence in anti-aging, repair, etc., and none of the four can be missing; and when turmeric root extract, spirulina extract and ergothioneine were replaced by other components with similar effects in comparative examples 8-10, the efficacy liquid of the prepared essence decreased to a certain extent, further illustrating that the components such as cyanobacteria extract, turmeric root extract, spirulina extract and ergothioneine in the formula of the present invention cooperate with each other to synergistically enhance the anti-aging and repairing effect of the essence, and its components cannot be conventionally replaced.

[0069] 3. Stability test:

[0070] The anti-aging repair essence prepared in Examples 1-5 was used as a test sample to test its stability. The specific results are as follows:

[0071] Internal control standards (2 months at 45±2°C and 2 months at -18±2°C) exceed national and light industry standards. Three high-low temperature cycle tests were conducted: 24 hours at 45±2°C and 24 hours at -18±2°C. The results are shown in Table 4.

[0072] Table 4

[0073]

[0074] The results in Table 4 show that the anti-aging repair essence prepared in the embodiment of the present invention has good stability in product application.

[0075] Finally, it should be noted that the above embodiments are intended to illustrate the technical solutions of the present invention rather than to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the essence and scope of the technical solutions of the present invention.

Claims

1. An anti-aging repair essence, characterized in that: The anti-aging repair essence comprises the following components in parts by weight: 5-55 parts of cyanobacteria extract, 0.08-1.3 parts of turmeric root extract, 0.1-1 parts of carnosine, 0.05-0.5 parts of spirulina maxima extract, 0.01-0.2 parts of hydrolyzed sodium hyaluronate, 0.01-0.2 parts of ergothioneine and 0.005-0.15 parts of acetyl hexapeptide-8.

2. The anti-aging repair essence according to claim 1, characterized in that The anti-aging repair essence comprises the following components in parts by weight: 20-50 parts of cyanobacteria extract, 0.15-0.9 parts of turmeric root extract, 0.2-0.5 parts of carnosine, 0.08-0.3 parts of spirulina maxima extract, 0.05-0.12 parts of hydrolyzed sodium hyaluronate, 0.05-0.12 parts of ergothioneine and 0.01-0.1 parts of acetyl hexapeptide-8.

3. The anti-aging repair essence according to claim 2, characterized in that: The anti-aging repair essence comprises the following components in parts by weight: 30 parts of cyanobacteria extract, 0.5 parts of turmeric root extract, 0.3 parts of carnosine, 0.15 parts of spirulina maxima extract, 0.1 parts of hydrolyzed sodium hyaluronate, 0.1 parts of ergothioneine and 0.08 parts of acetyl hexapeptide-8.

4. The anti-aging repair essence according to any one of claims 1 to 3, characterized in that The anti-aging repair essence further comprises the following components in parts by weight: 0.8-15.5 parts of a moisturizing agent, 0.06-1.2 parts of a thickener, 0.005-0.1 parts of a chelating agent, and 0.1-0.8 parts of a preservative.

5. The anti-aging repair essence according to claim 4, characterized in that The moisturizing agent includes at least one of butylene glycol, polyglycerol-10, 1,2-hexanediol, caprylyl glycol and lactobacillus fermentation product.

6. The anti-aging repair essence according to claim 4, characterized in that: The thickener includes at least one of ammonium acryloyldimethyltaurate / VP copolymer and sodium polyacryloyldimethyltaurate.

7. The anti-aging repair essence according to claim 4, characterized in that The chelating agent includes disodium EDTA.

8. The anti-aging repair essence according to claim 4, characterized in that: The preservative includes at least one of p-hydroxyacetophenone, phenoxyethanol and ethylhexylglycerin.

9. Use of the anti-aging repair essence according to any one of claims 1 to 8 in cosmetics.

10. The method for preparing the anti-aging repair essence according to any one of claims 4 to 8, characterized in that: The following steps are involved: S1. Stir and mix the moisturizer, thickener, and chelating agent, homogenize at 82-85° C. for 3-7 minutes until completely dissolved, and keep warm for 15-25 minutes to obtain mixture A; S2. Cooling the mixture A to 55-60° C., adding the cyanobacteria extract and the preservative, and stirring under vacuum to obtain a mixture B; S3. Cooling the mixture B to below 40° C., adding turmeric root extract, carnosine, Spirulina maxima extract, hydrolyzed sodium hyaluronate, ergothioneine and acetyl hexapeptide-8, and stirring for 15-25 minutes to obtain the anti-aging repair essence.

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