Traditional Chinese medicine health care wine and preparation method thereof

Abstract

The invention belongs to the technical field of traditional Chinese medicines, particularly relates to traditional Chinese medicine health-care wine with kidney-tonifying and yang-strengthening effects, and further discloses a preparation method of the traditional Chinese medicine health-care wine. The traditional Chinese medicine health care wine is prepared from cistanche, raspberry, cassia seed, fingered citron, longan aril, cinnamon, donkey-hide gelatin, poria cocos, houttuynia cordata, polygonatum kingianum, angelica sinensis, lalang grass rhizome, saffron crocus, American ginseng, astragalus membranaceus, codonopsis pilosula, lucid ganoderma, gastrodia elata, folium cortex eucommiae and rehmannia as medicinal raw materials, is brewed with dozens of pure natural Chinese herbal medicines, is prepared from true materials and solid materials, does not contain any western medicine components and chemical hormones, and is free of toxic and side effects. The national medicine and food homology regulation is met.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine health wine with kidney-tonifying and yang-strengthening effects, and further discloses a preparation method thereof. Background Art

[0002] Male sexual dysfunction is a common condition, especially with increasing stress in people's lives. Statistics show that the incidence rate is approximately 10% among adult males. Male sexual function is an extremely complex physiological process, resulting from the synergistic effects of various factors, including neurological, psychiatric, endocrine, and sexual organs.

[0003] According to Traditional Chinese Medicine, sexual dysfunction is primarily related to the kidneys. Kidney Yang deficiency is often caused by factors such as a congenital deficiency of Yang, kidney deficiency due to aging, chronic illness, and excessive sexual activity. Clinical manifestations include: soreness and weakness in the waist and knees, aversion to cold and cold limbs, particularly in the lower extremities; dizziness and lethargy; pale or dark complexion; a pale, thick tongue with a white coating; a weak pulse or impotence; uterine cold and infertility in women; persistent diarrhea, undigested food, early morning diarrhea; edema, especially below the waist, with a concave area that cannot be lifted when pressed; and even abdominal distension and pain, palpitations, cough, and asthma. With the accelerating pace of life and increasing social pressures, the number of patients suffering from kidney Yang deficiency is increasing, particularly in men with impotence. Currently, Traditional Chinese Medicine treatments can regulate overall body functions, strengthen the kidneys and enhance yang, and correct abnormalities in kidney function, demonstrating a significant therapeutic effect for male sexual dysfunction.

[0004] Developing health-care medicated alcoholic drinks using traditional Chinese medicines with kidney-tonifying and yang-strengthening properties is a relatively common kidney-tonifying and yang-strengthening product on the market. Cistanche deserticola is a traditional Chinese medicinal material with kidney-tonifying and yang-strengthening properties, as well as laxative effects. It is commonly used to treat symptoms such as kidney deficiency, impotence, spermatorrhea, soreness of the waist and knees, and constipation. It is suitable for treating impotence, premature ejaculation, soreness of the waist and knees, and other conditions caused by kidney yang deficiency. Currently, numerous traditional Chinese medicine health-care alcoholic drinks with Cistanche deserticola as the primary active ingredient have been developed. However, Cistanche deserticola itself contains certain tannins, which result in a relatively "astringent" taste in the medicinal drinks made with it. Although attempts have been made to remove tannins through various extraction methods to reduce the astringency, the extraction process not only increases the number of steps required but is also not suitable for general alcoholic drinks. Summary of the Invention

[0005] The purpose of the present invention is to provide a Chinese medicinal health wine with kidney-tonifying and yang-strengthening effects, and further disclose a preparation method thereof, so as to solve the problems raised in the above-mentioned background technology.

[0006] To achieve the above objectives, the present invention provides the following technical solutions.

[0007] A Chinese herbal health wine, the raw materials of which include: 30-50 parts by weight of Cistanche deserticola, 25-40 parts by weight of raspberry, 20-30 parts by weight of cassia seed, 5-12 parts by weight of bergamot, 8-15 parts by weight of longan meat, 3-10 parts by weight of cinnamon, 3-10 parts by weight of donkey-hide gelatin, 5-15 parts by weight of Poria, 3-10 parts by weight of Houttuynia cordata, 3-10 parts by weight of Polygonatum, 5-12 parts by weight of Angelica sinensis, 2-8 parts by weight of Imperata rhizome, 5-15 parts by weight of saffron, 5-15 parts by weight of American ginseng, 2-8 parts by weight of Astragalus, 1-5 parts by weight of Codonopsis pilosula, 1-5 parts by weight of Ganoderma lucidum, 1-3 parts by weight of Gastrodia elata, 1-3 parts by weight of Eucommia ulmoides leaves, and 1-5 parts by weight of Rehmannia glutinosa.

[0008] Specifically, the raw materials of the Chinese herbal health wine include: 35-45 parts by weight of Cistanche deserticola, 30-35 parts by weight of Raspberry, 22-28 parts by weight of Cassia seed, 6-10 parts by weight of Buddha's hand, 10-13 parts by weight of longan meat, 5-8 parts by weight of cinnamon bark, 5-8 parts by weight of donkey-hide gelatin, 8-12 parts by weight of Poria cocos, 5-8 parts by weight of Houttuynia cordata, 5-8 parts by weight of Polygonatum sibiricum, 7-10 parts by weight of Angelica sinensis, 3-6 parts by weight of Imperata cylindrica root, 8-12 parts by weight of Saffron, 8-12 parts by weight of American ginseng, 3-6 parts by weight of Astragalus, 2-4 parts by weight of Codonopsis pilosula, 2-4 parts by weight of Ganoderma lucidum, 1.5-2.5 parts by weight of Gastrodia elata, 1.5-2.5 parts by weight of Eucommia ulmoides leaves, and 2-4 parts by weight of Rehmannia glutinosa.

[0009] Specifically, the raw materials of the Chinese herbal health wine include: 40 parts by weight of Cistanche deserticola, 32 parts by weight of Raspberry, 25 parts by weight of Cassia seed, 8 parts by weight of Buddha's hand, 12 parts by weight of longan meat, 6 parts by weight of cinnamon bark, 6 parts by weight of donkey-hide gelatin, 10 parts by weight of Poria, 6 parts by weight of Houttuynia cordata, 6 parts by weight of Polygonatum, 8 parts by weight of Angelica sinensis, 5 parts by weight of Imperata rhizome, 10 parts by weight of Saffron, 10 parts by weight of American ginseng, 5 parts by weight of Astragalus, 3 parts by weight of Codonopsis pilosula, 3 parts by weight of Ganoderma lucidum, 2 parts by weight of Gastrodia elata, 2 parts by weight of Eucommia ulmoides leaves, and 3 parts by weight of Rehmannia glutinosa.

[0010] The present invention also provides a preparation method of the traditional Chinese medicine health wine, comprising the steps of taking the Cistanche deserticola, raspberry, cassia seed, bergamot, longan meat, cinnamon, donkey-hide gelatin, Poria, Houttuynia cordata, Polygonatum sibiricum, Chinese angelica, Imperata rhizome, saffron, American ginseng, astragalus, Codonopsis pilosula, Ganoderma lucidum, Gastrodia elata, Eucommia ulmoides leaf and Rehmannia glutinosa according to selected weight portions, mixing the mixture, and then adding white wine for soaking.

[0011] Specifically, the method for preparing the traditional Chinese medicine health wine further includes the step of pre-treating the Cistanche deserticola, raspberry, cassia seed, bergamot, longan meat, cinnamon, donkey-hide gelatin, Poria, Houttuynia cordata, Polygonatum sibiricum, Angelica sinensis, Imperata rhizome, saffron, American ginseng, astragalus, Codonopsis pilosula, Ganoderma lucidum, Gastrodia elata, Eucommia ulmoides leaf and / or Rehmannia glutinosa by nine steaming and nine drying.

[0012] Specifically, the preparation method of the traditional Chinese medicine health wine is as follows: The steaming temperature in the nine-steaming and nine-drying pretreatment step is 80-90°C and the steaming time is 10-30 minutes; The drying method in the nine-steaming and nine-drying pretreatment step is natural drying.

[0013] Specifically, the method for preparing the traditional Chinese medicine health wine comprises the following steps of steaming and drying the Cistanche deserticola nine times: (1) Washing and slicing the Cistanche deserticola, and then steaming it under low heat, and naturally cooling the steamed Cistanche deserticola to room temperature; then mixing the Cistanche deserticola with brown rice, and spraying a probiotic suspension on the surface of the mixture for natural fermentation; after the fermentation is completed, separating the Cistanche deserticola from the brown rice, and airing the Cistanche deserticola until dry, completing the steaming and drying process; (2) Repeat the above steaming-drying process seven times to complete the eight-steaming and eight-drying process; (3) Continue to steam the Cistanche deserticola with a slow fire and air-dry it until dry, completing the nine-steaming and nine-drying process.

[0014] Specifically, in the method for preparing the traditional Chinese medicine health wine, in the step (1), the probiotic suspension includes a suspension of Eurotium cristatum spores; The concentration of the spore suspension of Eurotium cristatum is 1×10 6 -1×10 7 cfu / mL.

[0015] Specifically, in the method for preparing the traditional Chinese medicine health wine, in the step (1), the material-liquid ratio of the mixture of the Cistanche deserticola and the brown rice to the Eurotium cristatum spore suspension is 10-20 g / 10 mL.

[0016] Specifically, in the method for preparing the traditional Chinese medicine health wine, in the step (1), the mass ratio of the Cistanche deserticola to the brown rice is 2-4:1.

[0017] Specifically, in the method for preparing the Chinese herbal health wine, in step (1): The temperature of the natural fermentation step is 25-30°C and the humidity is 50-70%; and / or, The fermentation period of the natural fermentation step is 5-7 days.

[0018] Compared with the prior art, the present invention has the following beneficial effects: The Chinese medicine health-care wine of the present invention uses Cistanche deserticola, raspberry, cassia seed, bergamot, longan pulp, cinnamon bark, donkey-hide gelatin, Poria, Houttuynia cordata, Polygonatum sibiricum, Chinese angelica, Imperata root, saffron, American ginseng, astragalus, Codonopsis pilosula, Ganoderma lucidum, Gastrodia elata, Eucommia ulmoides leaf and Rehmannia glutinosa as medicinal raw materials. It is brewed with more than a dozen pure natural Chinese herbal medicines, is made of authentic materials, does not contain any Western medicine ingredients and chemical hormones, and complies with the national regulations on the same origin of medicine and food.

[0019] In the Chinese medicinal health wine of the present invention: Cistanche deserticola is warm in nature, sweet and salty in taste, and has a tonic effect. It can nourish qi and blood, and harmonize the spleen and stomach. Cistanche deserticola mainly enters the kidney meridian and has the effects of nourishing the kidney, strengthening yang, and replenishing essence and blood. It is suitable for symptoms such as soreness of the waist and knees, impotence, premature ejaculation, and spermatorrhea caused by kidney yang deficiency. Raspberry is warm in nature, sweet and sour in taste, and mainly enters the kidney meridian. It has the effects of nourishing the kidney, consolidating essence, and reducing urine. It is suitable for symptoms such as spermatorrhea, spermatorrhea, and frequent urination caused by kidney deficiency. Cassia seed is slightly cold in nature, sweet, bitter and salty in taste, and has the effect of clearing away heat. It mainly enters the liver meridian and has the effect of clearing the liver and improving eyesight. It is suitable for symptoms such as red, swollen and painful eyes, and blurred vision caused by liver fire. Buddha's hand is warm in nature, pungent, bitter and sour in taste, and has the effect of warming the middle and dispersing cold. It mainly enters the liver meridian and has the effect of soothing the liver and regulating qi. It is suitable for symptoms such as chest and flank pain, and abdominal distension caused by liver qi stagnation. Longan meat is warm in nature and sweet in taste. It mainly enters the heart meridian and has the effect of nourishing the heart and calming the mind. It is suitable for symptoms such as palpitations, insomnia, and forgetfulness caused by deficiency of both the heart and spleen. Cinnamon bark is very hot in nature, pungent and sweet in taste, and has a strong effect of warming yang and dispersing cold. It mainly enters the kidney meridian and has the effect of replenishing fire and supporting yang. It is suitable for symptoms such as cold pain in the waist and knees, impotence, and frequent urination caused by kidney yang deficiency. Donkey-hide gelatin is mild in nature and sweet in taste. It has a tonic effect, can nourish qi and blood, and harmonize the spleen and stomach. It mainly enters the lung meridian and has the effect of nourishing yin and moistening dryness. It is suitable for dry cough and hemoptysis caused by lung yin deficiency. Poria cocos is mild in nature, sweet and light in taste, and mainly enters the heart meridian. It has the effect of calming the mind and soothing the nerves. It is suitable for symptoms such as palpitations and insomnia caused by deficiency of both the heart and spleen. Houttuynia cordata is slightly cold in nature and pungent in taste. It has the function of clearing away heat and detoxifying. It mainly enters the lung meridian and has the effects of clearing heat and detoxifying, promoting lung function and relieving cough. It is suitable for cough and sputum caused by lung heat. Polygonatum sibiricum is mild in nature and sweet in taste. It has a tonic effect and mainly enters the spleen meridian. It has the effect of tonifying the spleen and replenishing qi. It is suitable for symptoms such as loss of appetite and fatigue caused by spleen deficiency. Angelica sinensis is warm in nature, sweet and spicy in taste, and has a warming and tonic effect. It mainly enters the liver meridian and has the effect of replenishing blood and activating blood circulation. It is suitable for symptoms such as pale complexion, dizziness, and irregular menstruation caused by blood deficiency. Imperata root is cold in nature and sweet in taste. It mainly enters the lung meridian and has the effect of clearing heat and promoting diuresis. It is suitable for cough and sputum caused by lung heat. Saffron is mild in nature and sweet in taste. It mainly enters the heart meridian and has the effect of promoting blood circulation and removing blood stasis. It is suitable for chest pain and heart pain caused by blood stasis. American ginseng is cool in nature, sweet and bitter in taste, and mainly enters the lung meridian. It has the effect of replenishing qi and nourishing yin, and is suitable for dry cough, hemoptysis, etc. caused by lung yin deficiency; Astragalus root is slightly warm in nature and sweet in taste. It mainly enters the spleen meridian and has the effect of replenishing qi and raising yang. It is suitable for symptoms such as shortness of breath, fatigue, and loss of appetite caused by spleen deficiency. Codonopsis pilosula is mild in nature and sweet in taste. It mainly enters the spleen meridian and has the effect of tonifying the middle and replenishing qi. It is suitable for symptoms such as shortness of breath, fatigue, and loss of appetite caused by spleen deficiency. Lingzhi is mild in nature and sweet in taste. It mainly enters the heart meridian and has the effect of replenishing qi and calming the mind. It is suitable for symptoms such as palpitations and insomnia caused by heart qi deficiency. Gastrodia elata is mild in nature and sweet in taste. It mainly enters the liver meridian and has the effect of calming the liver and extinguishing wind. It is suitable for headaches and dizziness caused by hyperactivity of liver yang. Eucommia leaves are warm in nature, sweet and slightly spicy in taste, and mainly enter the liver meridian. They have the effect of nourishing the liver and kidneys, and are suitable for symptoms such as soreness of the waist and knees, dizziness, etc. caused by liver and kidney deficiency. Rehmannia root is cold in nature, sweet and bitter in taste, and mainly enters the kidney meridian. It has the effect of nourishing yin and tonifying the kidney. It is suitable for symptoms such as soreness of the waist and knees, and spermatorrhea caused by kidney yin deficiency.

[0020] The Chinese medicinal health wine of the present invention has the effects of nourishing the kidneys and delaying ejaculation, consolidating essence and strengthening the kidneys, and nourishing yin and tonifying the kidneys. It has significant effects on impotence, premature ejaculation, mid-course fatigue, night sweats and spermatorrhea, and soreness of the waist and knees. It is not only effective for men with weak erections, erections that are not hard, hard erections that are not firm, and erections that do not last long, but also has similar effects on women, who do not feel tired or weak after sex, and remain energetic and full of spirits.

[0021] The Chinese medicinal health-care wine of the present invention is prepared by a nine-steaming and nine-processing process for all raw materials and is made through multiple steps of ancient secret methods. In particular, the wine is produced from pure grains and stored in a wine cellar, making it more suitable for drinking.

[0022] The traditional Chinese medicine health wine of the present invention utilizes a co-fermentation method with Eurotium cristatum during the preparation of the medicinal material, effectively improving the composition and properties of the Cistanche deserticola and reducing its tannin content. This ensures that the medicinal wine has no astringent taste during brewing, making it suitable for consumption. In particular, the unique aroma developed by Eurotium cristatum during fermentation further improves the aroma and taste of the brewed medicinal wine.

[0023] The Chinese medicinal health wine of the present invention can simultaneously carry out probiotic fermentation during the preparation and drying of medicinal materials, and can complete the sterilization operation by steaming. No additional modification and active ingredient extraction treatment are required, and the prepared Cistanche deserticola can be directly used for soaking in wine, which is easy to operate and has better nutritional content. DETAILED DESCRIPTION

[0024] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0025] In the following embodiments of the present invention, the Eurotium cristatum used can be a conventional strain commercially available in the art, for example, the Eurotium cristatum BMZ136998 commercially available from Mingzhou Bio, the Eurotium cristatum CICC-41041 commercially available from Zhongke Ruipu, or the Eurotium cristatum screened by those skilled in the art can complete the above process.

[0026] In the following embodiments of the present invention, the spore suspension of Eurotium cristatum is prepared by uniformly dispersing the spores of Eurotium cristatum in water. The concentration of the spore suspension of Eurotium cristatum is exemplarily adjusted to 1×10 6 -1×10 7 cfu / mL.

[0027] In the following embodiments of the present invention, the Chinese medicinal raw materials selected for the Chinese medicinal health wine, including Cistanche deserticola, raspberry, cassia seed, bergamot, longan meat, cinnamon, donkey-hide gelatin, Poria, Houttuynia cordata, Polygonatum sibiricum, Angelica sinensis, Imperata rhizome, saffron, American ginseng, Astragalus membranaceus, Codonopsis pilosula, Ganoderma lucidum, Gastrodia elata, Eucommia ulmoides leaf and Rehmannia glutinosa, are all commercially available medicinal materials in this field.

[0028] Preparation Example 1 Take commercially available Cistanche deserticola, wash it thoroughly, dry it, and then slice it for later use.

[0029] The sliced Cistanche deserticola was steamed under conventional low heat at a controlled temperature of 80°C for 30 minutes. The steamed Cistanche deserticola was taken out and naturally cooled to room temperature. The Cistanche deserticola and brown rice were then fully mixed at a mass ratio of 2:1, and the surface of the mixture was evenly sprayed with the suspension of Eurotium cristatum spores (1×10 6 cfu / mL), the solid-liquid ratio of the mixture of Cistanche deserticola and brown rice to the Eurotium cristatum spore suspension was controlled to be 10g / 10mL, and after being evenly sprayed, the mixture of Cistanche deserticola and brown rice was placed at room temperature and 50% humidity for natural fermentation for 7 days. After fermentation, the Cistanche deserticola was separated from the brown rice by conventional filtration, and the Cistanche deserticola was continued to be naturally aired until dry, completing the steaming and sun-drying process.

[0030] Repeat the above steaming-drying process seven times, completing a total of eight steaming and eight drying processes.

[0031] The separated and dried Cistanche deserticola is then steamed under low heat according to the aforementioned conditions, taken out and naturally air-dried until dry, completing the nine-steaming and nine-drying process to obtain the processed Cistanche deserticola.

[0032] Preparation Example 2 Take commercially available Cistanche deserticola, wash it thoroughly, dry it, and then slice it for later use.

[0033] The sliced Cistanche deserticola was steamed under conventional low heat at a controlled temperature of 85°C for 20 minutes. The steamed Cistanche deserticola was taken out and naturally cooled to room temperature. The Cistanche deserticola and brown rice were then fully mixed at a mass ratio of 3:1, and the surface of the mixture was evenly sprayed with the suspension of Eurotium cristatum spores (5×10 6 cfu / mL), the solid-liquid ratio of the mixture of Cistanche deserticola and brown rice to the Eurotium cristatum spore suspension was controlled to be 15g / 10mL. After spraying evenly, the mixture of Cistanche deserticola and brown rice was placed at 28°C and 60% humidity for natural fermentation for 6 days. After fermentation, the Cistanche deserticola was separated from the brown rice by conventional filtration, and the Cistanche deserticola was continued to be naturally aired until dry, completing the steaming and sun-drying process.

[0034] Repeat the above steaming-drying process seven times, completing a total of eight steaming and eight drying processes.

[0035] The separated and dried Cistanche deserticola is then steamed under low heat according to the aforementioned conditions, taken out and naturally air-dried until dry, completing the nine-steaming and nine-drying process to obtain the processed Cistanche deserticola.

[0036] Preparation Example 3 Take commercially available Cistanche deserticola, wash it thoroughly, dry it, and then slice it for later use.

[0037] The sliced Cistanche deserticola was steamed under conventional low heat at a controlled steaming temperature of 90°C for 10 minutes. The steamed Cistanche deserticola was taken out and naturally cooled to room temperature. The Cistanche deserticola and brown rice were then fully mixed at a mass ratio of 4:1, and the surface of the mixture was evenly sprayed with the suspension of Eurotium cristatum spores (1×10 7 cfu / mL), the solid-liquid ratio of the mixture of Cistanche deserticola and brown rice to the Eurotium cristatum spore suspension was controlled to be 20g / 10mL. After spraying evenly, the mixture of Cistanche deserticola and brown rice was placed at 10°C and 70% humidity for natural fermentation for 5 days. After fermentation, the Cistanche deserticola was separated from the brown rice by conventional filtration, and the Cistanche deserticola was continued to be naturally air-dried until dry, completing the steaming and sun-drying process.

[0038] Repeat the above steaming-drying process seven times, completing a total of eight steaming and eight drying processes.

[0039] The separated and dried Cistanche deserticola is then steamed under low heat according to the aforementioned conditions, taken out and naturally air-dried until dry, completing the nine-steaming and nine-drying process to obtain the processed Cistanche deserticola.

[0040] Preparation Example 4 Take commercially available Cistanche deserticola, thoroughly clean and dry it, then slice it and perform a nine-steaming and nine-drying process according to the following steaming and airing parameters: Steaming: Control the steaming temperature to 85°C and the steaming time to 20 minutes; Drying: Dry naturally until the drying requirements are met.

[0041] Preparation Example 5 Commercially available raspberries, cassia seeds, bergamot, longan pulp, cinnamon bark, donkey-hide gelatin, poria, houttuynia cordata, polygonatum, angelica, imperata root, saffron, American ginseng, astragalus, codonopsis, ganoderma lucidum, gastrodia elata, eucommia leaf, and rehmannia root were taken and steamed and air-dried nine times according to the following steaming and air-drying parameters: Steaming: Control the steaming temperature to 85°C and the steaming time to 20 minutes; Drying: Dry naturally until the drying requirements are met.

[0042] Example 1 The Chinese herbal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment comprises the following raw materials: 40 parts by weight of Cistanche deserticola, 32 parts by weight of Raspberry, 25 parts by weight of Cassia seed, 8 parts by weight of Buddha's hand, 12 parts by weight of longan pulp, 6 parts by weight of cinnamon bark, 6 parts by weight of donkey-hide gelatin, 10 parts by weight of Poria, 6 parts by weight of Houttuynia cordata, 6 parts by weight of Polygonatum, 8 parts by weight of Angelica sinensis, 5 parts by weight of Imperata rhizome, 10 parts by weight of Saffron, 10 parts by weight of American ginseng, 5 parts by weight of Astragalus, 3 parts by weight of Codonopsis pilosula, 3 parts by weight of Ganoderma lucidum, 2 parts by weight of Gastrodia elata, 2 parts by weight of Eucommia ulmoides leaves, and 3 parts by weight of Rehmannia glutinosa.

[0043] In the Chinese herbal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment, the Cistanche deserticola is obtained by processing according to the processing method in Preparation Example 1, and the other medicinal materials are processed according to the method in Preparation Example 5.

[0044] The method for brewing the Chinese medicinal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment can be prepared by adopting the traditional wine-brewing method in the art, that is, taking the raw medicinal materials according to the above-selected ratio, adding 45-degree alcohol liquor for brewing.

[0045] Example 2 The Chinese herbal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment comprises the following raw materials: 35 parts by weight of Cistanche deserticola, 35 parts by weight of Raspberry, 22 parts by weight of Cassia seed, 10 parts by weight of Buddha's hand, 10 parts by weight of longan pulp, 8 parts by weight of cinnamon bark, 5 parts by weight of donkey-hide gelatin, 12 parts by weight of Poria, 5 parts by weight of Houttuynia cordata, 8 parts by weight of Polygonatum, 7 parts by weight of Angelica sinensis, 6 parts by weight of Imperata rhizome, 8 parts by weight of Saffron, 12 parts by weight of American ginseng, 3 parts by weight of Astragalus, 4 parts by weight of Codonopsis pilosula, 2 parts by weight of Ganoderma lucidum, 2.5 parts by weight of Gastrodia elata, 1.5 parts by weight of Eucommia ulmoides leaves, and 4 parts by weight of Rehmannia glutinosa.

[0046] In the Chinese herbal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment, the Cistanche deserticola is obtained by processing according to the processing method in Preparation Example 1, and the other medicinal materials are processed according to the method in Preparation Example 5.

[0047] The method for brewing the Chinese medicinal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment can be prepared by adopting the traditional wine-brewing method in the art, that is, taking the raw medicinal materials according to the above-selected ratio, adding 38-degree alcohol liquor for brewing.

[0048] Example 3 The Chinese herbal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment comprises the following raw materials: 45 parts by weight of Cistanche deserticola, 30 parts by weight of raspberry, 28 parts by weight of cassia seed, 6 parts by weight of bergamot, 13 parts by weight of longan pulp, 5 parts by weight of cinnamon bark, 8 parts by weight of donkey-hide gelatin, 8 parts by weight of Poria cocos, 8 parts by weight of Houttuynia cordata, 5 parts by weight of Polygonatum sibiricum, 10 parts by weight of Angelica sinensis, 3 parts by weight of Imperata rhizome, 12 parts by weight of Saffron, 8 parts by weight of American ginseng, 6 parts by weight of Astragalus, 2 parts by weight of Codonopsis pilosula, 4 parts by weight of Ganoderma lucidum, 1.5 parts by weight of Gastrodia elata, 2.5 parts by weight of Eucommia ulmoides leaves, and 2 parts by weight of Rehmannia glutinosa.

[0049] In the Chinese herbal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment, the Cistanche deserticola is obtained by processing according to the processing method in Preparation Example 1, and the other medicinal materials are processed according to the method in Preparation Example 5.

[0050] The method for brewing the Chinese medicinal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment can be achieved by adopting the traditional wine-brewing method in the art, that is, taking the raw medicinal materials according to the above-selected ratio, adding 52-degree alcohol liquor for brewing.

[0051] Example 4 The Chinese herbal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment comprises the following raw materials: 30 parts by weight of Cistanche deserticola, 40 parts by weight of Raspberry, 20 parts by weight of Cassia seed, 12 parts by weight of Buddha's hand, 8 parts by weight of longan pulp, 10 parts by weight of cinnamon bark, 3 parts by weight of donkey-hide gelatin, 15 parts by weight of Poria, 3 parts by weight of Houttuynia cordata, 10 parts by weight of Polygonatum, 5 parts by weight of Angelica sinensis, 8 parts by weight of Imperata rhizome, 5 parts by weight of Saffron, 15 parts by weight of American ginseng, 2 parts by weight of Astragalus, 5 parts by weight of Codonopsis pilosula, 1 part by weight of Ganoderma lucidum, 3 parts by weight of Gastrodia elata, 1 part by weight of Eucommia ulmoides leaf, and 5 parts by weight of Rehmannia glutinosa.

[0052] In the Chinese herbal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment, the Cistanche deserticola is obtained by processing according to the processing method in Preparation Example 1, and the other medicinal materials are processed according to the method in Preparation Example 5.

[0053] The method for brewing the Chinese medicinal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment can be achieved by adopting the traditional wine-brewing method in the art, that is, taking the raw medicinal materials according to the above-selected ratio, adding 40-degree alcohol liquor for brewing.

[0054] Example 5 The Chinese herbal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment comprises the following raw materials: 50 parts by weight of Cistanche deserticola, 25 parts by weight of Raspberry, 30 parts by weight of Cassia seed, 5 parts by weight of Buddha's hand, 15 parts by weight of longan pulp, 3 parts by weight of cinnamon bark, 10 parts by weight of donkey-hide gelatin, 5 parts by weight of Poria, 10 parts by weight of Houttuynia cordata, 3 parts by weight of Polygonatum, 12 parts by weight of Angelica sinensis, 2 parts by weight of Imperata rhizome, 15 parts by weight of Saffron, 5 parts by weight of American ginseng, 8 parts by weight of Astragalus, 1 part by weight of Codonopsis pilosula, 5 parts by weight of Ganoderma lucidum, 1 part by weight of Gastrodia elata, 3 parts by weight of Eucommia ulmoides leaf, and 1 part by weight of Rehmannia glutinosa.

[0055] In the Chinese herbal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment, the Cistanche deserticola is obtained by processing according to the processing method in Preparation Example 1, and the other medicinal materials are processed according to the method in Preparation Example 5.

[0056] The method for brewing the Chinese medicinal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment can be prepared by adopting the traditional wine-making method in this field, that is, taking the raw medicinal materials according to the above-selected ratio, adding 42-degree alcohol liquor for brewing.

[0057] Example 6 The Chinese medicinal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment has the same raw material composition as that in Example 1.

[0058] In the Chinese herbal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment, the Cistanche deserticola is obtained by processing according to the processing method in Preparation Example 4, and the other medicinal materials are processed according to the method in Preparation Example 5.

[0059] The method for brewing the Chinese medicinal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment can be prepared by adopting the traditional wine-brewing method in the art, that is, taking the raw medicinal materials according to the above-selected ratio, adding 45-degree alcohol liquor for brewing.

[0060] Example 7 The Chinese medicinal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment has the same raw material composition as that in Example 1.

[0061] In the Chinese medicinal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment, the Cistanche deserticola is not processed in any way, and the remaining medicinal materials are processed according to the method in Preparation Example 5.

[0062] The method for brewing the Chinese medicinal health wine with kidney-tonifying and yang-strengthening effects described in this embodiment can be prepared by adopting the traditional wine-brewing method in the art, that is, taking the raw medicinal materials according to the above-selected ratio, adding 45-degree alcohol liquor for brewing.

[0063] Experimental example 1. Tannin content test In this experimental example, the processed Cistanche deserticola in Preparation Example 1 and Preparation Example 4 were respectively taken for tannin content testing, and the same batch of Cistanche deserticola without any treatment was used as a control.

[0064] The above-mentioned Cistanche deserticola samples were ground into powder respectively. 1 g of the ground Cistanche deserticola powder was dissolved in 30 ml of 70% ethanol and ultrasonically extracted for 30 minutes. After filtration, the tannin content of the extract was determined using the phenolphthalein reagent method according to the following formula: ; Wherein, DN represents the tannin content, A represents the absorbance measured at a wavelength of 765 nm, D represents the dilution factor, i.e. the dilution ratio of the extract, C represents the concentration of the extract, and M represents the sample weight.

[0065] The tannin content values in different Cistanche deserticola samples were recorded respectively and recorded in Table 1 below.

[0066] Table 1 Tannin content of Cistanche deserticola samples It can be seen that the present invention can effectively reduce the tannin content in Cistanche deserticola by adding Eurotium cristatum to the nine-steaming and nine-drying process of Cistanche deserticola for co-fermentation and utilizing the unique fermentation performance of Eurotium cristatum.

[0067] 2. Taste of medicinal wine The medicinal liquors were brewed for 30 days according to the methods in Examples 1, 6 and 7 above, and the brewed medicinal liquors were tested for taste. The evaluation results are recorded in Table 2 below.

[0068] Table 2 Taste evaluation results of medicinal wine samples It can be seen that the present invention can effectively reduce the tannin content in Cistanche deserticola by adding Eurotium cristatum to the nine-steaming and nine-drying process of Cistanche deserticola for co-fermentation, utilizing the unique fermentation performance of Eurotium cristatum, thereby improving the taste of Cistanche deserticola soaked in wine, especially the unique fermented aged flavor of Eurotium cristatum, supplemented by the aroma of traditional Chinese medicine and wine, and the aroma is coordinated, so that the taste of the medicinal wine is better.

[0069] 3. Kidney-tonifying and yang-strengthening effects The raw materials selected for the Chinese herbal health wine of the present invention have typical kidney-tonifying and yang-strengthening effects. This experimental example further verifies the kidney-tonifying and yang-strengthening effects of the medicinal wine prepared in Example 1 (infused for 30 days) using a known method in the prior art.

[0070] This experimental example refers to the method described in Chinese patent CN106511762B to test the effects of the health-care medicinal wine on tonifying the kidney and strengthening yang, and promoting yang and relieving impotence.

[0071] Thirty male SD rats weighing 250 ± 20 g were randomly selected and bilateral testicles were removed. Penicillin was injected intramuscularly after surgery. Three days after castration, the rats were randomly divided into two groups of 10 rats each, designated as the castration model group and the experimental group. The remaining 10 rats served as the normal control group.

[0072] The rats in the experimental groups were gavaged with the medicinal wine for 30 consecutive days, 15 ml per day; the rats in the castration model group were gavaged with the same amount of normal saline; and the normal control group received no treatment.

[0073] On the 30th day of the experiment, the stimulation electrodes of the multi-purpose electronic acupoint measuring instrument were placed on the rat's penis, and the electrode stimulation intensity was 3 mA. The penile erection latency (i.e., the interval from the start of stimulation to the penile erection) was recorded. The results are shown in Table 3 below.

[0074] Table 3 Penile erection latency It can be seen that the Chinese medicinal health wine of the present invention can increase the excitability of the penis of castrated male rats to external stimulation, has the effect of shortening the erection latency period of the penis of male rats, and has a certain kidney-tonifying and yang-strengthening effect.

[0075] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the invention can be embodied in other specific forms without departing from the spirit or essential characteristics of the invention. Therefore, the embodiments should be considered in all respects as illustrative and non-restrictive, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations that come within the meaning and range of equivalents of the claims be embraced therein.

[0076] In addition, it should be understood that although this specification is described in terms of implementation methods, not every implementation method contains only one independent technical solution. This narrative method of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment can also be appropriately combined to form other implementation methods that can be understood by those skilled in the art.

Claims

1. A Chinese medicinal health wine, characterized in that: The raw material medicine composition of the Chinese medicine health wine includes: 30-50 parts by weight of Cistanche deserticola, 25-40 parts by weight of raspberry, 20-30 parts by weight of cassia seed, 5-12 parts by weight of bergamot, 8-15 parts by weight of longan meat, 3-10 parts by weight of cinnamon, 3-10 parts by weight of donkey-hide gelatin, 5-15 parts by weight of Poria, 3-10 parts by weight of Houttuynia cordata, 3-10 parts by weight of Polygonatum, 5-12 parts by weight of Angelica sinensis, 2-8 parts by weight of Imperata rhizome, 5-15 parts by weight of saffron, 5-15 parts by weight of American ginseng, 2-8 parts by weight of Astragalus, 1-5 parts by weight of Codonopsis pilosula, 1-5 parts by weight of Ganoderma lucidum, 1-3 parts by weight of Gastrodia elata, 1-3 parts by weight of Eucommia ulmoides leaves, and 1-5 parts by weight of Rehmannia glutinosa.

2. The Chinese medicinal health wine according to claim 1, characterized in that: The raw material medicine composition of the Chinese medicine health wine includes: 35-45 parts by weight of Cistanche deserticola, 30-35 parts by weight of Raspberry, 22-28 parts by weight of Cassia seed, 6-10 parts by weight of Buddha's hand, 10-13 parts by weight of longan meat, 5-8 parts by weight of cinnamon bark, 5-8 parts by weight of donkey-hide gelatin, 8-12 parts by weight of Poria cocos, 5-8 parts by weight of Houttuynia cordata, 5-8 parts by weight of Polygonatum sibiricum, 7-10 parts by weight of Angelica sinensis, 3-6 parts by weight of Imperata cylindrica root, 8-12 parts by weight of Saffron, 8-12 parts by weight of American ginseng, 3-6 parts by weight of Astragalus, 2-4 parts by weight of Codonopsis pilosula, 2-4 parts by weight of Ganoderma lucidum, 1.5-2.5 parts by weight of Gastrodia elata, 1.5-2.5 parts by weight of Eucommia ulmoides leaves, and 2-4 parts by weight of Rehmannia glutinosa.

3. The Chinese medicinal health wine according to claim 1 or 2, characterized in that: The raw material medicine composition of the Chinese medicine health wine includes: 40 parts by weight of Cistanche deserticola, 32 parts by weight of Raspberry, 25 parts by weight of Cassia seed, 8 parts by weight of Buddha's hand, 12 parts by weight of longan meat, 6 parts by weight of cinnamon bark, 6 parts by weight of donkey-hide gelatin, 10 parts by weight of Poria, 6 parts by weight of Houttuynia cordata, 6 parts by weight of Polygonatum, 8 parts by weight of Angelica sinensis, 5 parts by weight of Imperata rhizome, 10 parts by weight of Saffron, 10 parts by weight of American ginseng, 5 parts by weight of Astragalus, 3 parts by weight of Codonopsis pilosula, 3 parts by weight of Ganoderma lucidum, 2 parts by weight of Gastrodia elata, 2 parts by weight of Eucommia ulmoides leaves, and 3 parts by weight of Rehmannia glutinosa.

4. A method for preparing the Chinese medicinal health wine according to any one of claims 1 to 3, characterized in that: The method comprises the steps of mixing the Cistanche deserticola, raspberry, cassia seed, bergamot, longan pulp, cinnamon bark, donkey-hide gelatin, Poria, houttuynia cordata, polygonatum, angelica, Imperata rhizome, saffron, American ginseng, astragalus, codonopsis pilosula, ganoderma lucidum, gastrodia elata, eucommia bark and rehmannia root according to selected weight portions, and then adding white wine for soaking.

5. The method for preparing the Chinese medicinal health wine according to claim 4, characterized in that: The method further comprises the step of pre-treating the herb by steaming and drying nine times, namely, the herb Cistanche deserticola, raspberry, cassia seed, bergamot, longan pulp, cinnamon bark, donkey-hide gelatin, Poria, houttuynia cordata, polygonatum, angelica, cogongrass root, saffron, American ginseng, astragalus, codonopsis pilosula, ganoderma lucidum, gastrodia elata, eucommia bark and / or rehmannia root.

6. The method for preparing the Chinese medicinal health wine according to claim 5, characterized in that: The steaming temperature in the nine-steaming and nine-drying pretreatment step is 80-90°C and the steaming time is 10-30 minutes; The drying method in the nine-steaming and nine-drying pretreatment step is natural drying.

7. The method for preparing the Chinese medicinal health wine according to claim 5 or 6, characterized in that: The nine-steaming and nine-drying pretreatment steps of Cistanche deserticola include: (1) Washing and slicing the Cistanche deserticola, and then steaming it under low heat, and naturally cooling the steamed Cistanche deserticola to room temperature; then mixing the Cistanche deserticola with brown rice, and spraying a probiotic suspension on the surface of the mixture for natural fermentation; after the fermentation is completed, separating the Cistanche deserticola from the brown rice, and airing the Cistanche deserticola until dry, completing the steaming and drying process; (2) Repeat the above steaming-drying process seven times to complete the eight-steaming and eight-drying process; (3) Continue to steam the Cistanche deserticola with a slow fire and air-dry it until dry, completing the nine-steaming and nine-drying process.

8. The method for preparing the Chinese medicinal health wine according to claim 7, characterized in that: In the step (1), the probiotic suspension includes a suspension of Eurotium cristatum spores; The concentration of the spore suspension of Eurotium cristatum is 1×10 6 -1×10 7 cfu / mL.

9. The method for preparing the Chinese medicinal health wine according to claim 8, characterized in that: In step (1): The mass ratio of the Cistanche deserticola to the brown rice is 2-4:1; and / or, The material-liquid ratio of the mixture of the Cistanche deserticola and the brown rice to the Eurotium cristatum spore suspension is 10-20 g / 10 mL.

10. The method for preparing the Chinese medicinal health wine according to claim 7, characterized in that: In step (1): The temperature of the natural fermentation step is 25-30°C and the humidity is 50-70%; and / or, The fermentation period of the natural fermentation step is 5-7 days.

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