A rapid cooling device for producing a pharmaceutical intermediate

Abstract

The application discloses a rapid cooling device for medical intermediate production, which comprises a cooling tank, an air cooling assembly and a material turning module, a feeding port is formed in the top of the cooling tank, an air inlet is formed in the circumferential surface of the cooling tank, a discharging assembly is arranged at the bottom of the cooling tank, and the air cooling assembly is arranged at the left side of the cooling tank; the material turning module comprises a material turning rod, a material turning ring, a material turning frame, a material turning plate, a protection plate, a hollow rod, a solid rod, a shielding plate and an air outlet, the material turning rod is rotatably arranged through the top of the cooling tank, the hollow rod is slowly moved downwards to slowly move the material turning frame downwards, the slowly moving material turning frame drives the material turning plate to slowly move downwards, the slowly moving material turning mode can turn the particles and avoid the compaction of the intermediate particles caused by excessive pressing, the particle layer is kept in a loose state, and the low-temperature cooling medium can smoothly penetrate the particle gaps, and the application has the characteristics of turning the intermediate particles.

Description

Technical Field

[0001] The invention relates to the technical field of intermediate production cooling, in particular to a rapid cooling device for the production of pharmaceutical intermediates. Background Art

[0002] Many reactions are prone to side reactions at high temperatures. For example, in the alkylation reaction of amine intermediates, overheating can lead to excessive substitution of raw materials and the generation of impurities. Cooling can stabilize the temperature within the process range, inhibit side reactions, and reduce the generation of invalid impurities. The air cooling component can maintain a low temperature environment to protect the activity and stability of pharmaceutical intermediates.

[0003] The patent with patent announcement number CN216716748U relates to the field of pharmaceutical intermediate production technology, specifically a rapid cooling device for pharmaceutical intermediate production, including two support frames, an electric conveyor belt is installed on the outer wall of the opposite end of the two support frames, and two fixed columns are installed on the outer walls of the opposite sides of the two support frames, a protective cover is installed on the outer wall of the opposite end of the two fixed columns, and the inner walls of both ends of the protective cover are rotatably connected to the first rotating shaft on both sides. This patent can cool the air drawn in by the vacuum pump by setting a refrigeration mechanism and turning on the semiconductor refrigerator. The drawn-in air then drives the third rotating shaft on the arc-shaped fan blade to rotate, thereby achieving sufficient air cooling. The cooled air enters the inside of the protective cover through the air outlet to cool the pharmaceutical intermediate. By using an electric conveyor belt for transportation, continuous cooling can be achieved, thereby improving cooling efficiency.

[0004] In the above patents, continuous cooling can be achieved by using an electric conveyor belt for transportation, thereby improving the cooling efficiency. However, most rapid cooling devices have a compact internal space to improve the heat exchange efficiency and lack a special turning mechanism. The intermediate particles that have not been turned over are difficult to fully contact with the cooling medium, which leads to a decrease in the cooling rate. In addition, the intermediate particles are easily compacted during the up and down turning process, and the density of the compacted particle layer increases. The porosity decreases, making it difficult for the cooling medium to penetrate the particle layer, further leading to a significant decrease in the cooling rate. Therefore, it is very necessary to design a rapid cooling device for the production of pharmaceutical intermediates that is highly practical and can turn over the intermediate particles. Summary of the Invention

[0005] The object of the present invention is to provide a rapid cooling device for producing pharmaceutical intermediates to solve the problems raised in the above background technology.

[0006] In order to solve the above technical problems, the present invention provides the following technical solutions: a rapid cooling device for the production of pharmaceutical intermediates, comprising a cooling tank and an air-cooling component, and also comprising a turning module, wherein the top of the cooling tank is provided with a feed port, the circumferential surface of the cooling tank is provided with an air inlet, the bottom of the cooling tank is provided with a discharge component, and the air-cooling component is arranged on the left side of the cooling tank; the turning module comprises a turning rod, a turning ring, a turning rack, a turning plate, a protective plate, a hollow rod, a solid rod, a baffle and an air outlet, and the turning rod rotates through the cooling tank At the top, the tipping ring is fixedly installed on the inner wall of the cooling tank, the tipping rack is slidably installed on the circumferential surface of the tipping rod, the tipping plate is fixedly installed on the bottom of the tipping rack, the protective plate is fixedly installed on the circumferential surface of the tipping rod, the hollow rod is fixed through the upper and lower walls of the protective plate, the solid rod is slidably installed on the inner wall of the hollow rod, the baffle is fixedly installed on the bottom of the inner wall of the hollow rod, the air outlet is opened at the bottom of the hollow rod, the hollow rod moves slowly downward, causing the tipping rack to move slowly downward, and the tipping rack moves slowly downward, driving the tipping plate to move slowly downward.

[0007] According to the above technical solution, the top of the solid rod is fixedly connected to the tipping rack, and a sealing ring is provided between the hollow rod and the solid rod. The sealing ring can increase the sealing between the hollow rod and the solid rod, and the bottom of the tipping ring is set as an arc surface. By setting the bottom of the tipping ring as an arc surface, the friction force when the tipping ring contacts the tipping rack can be reduced.

[0008] According to the above technical solution, the tipping rack is in conflict with the tipping ring, and a protective spring is arranged between the protective plate and the tipping rack. The tipping rack moves downward to squeeze the protective spring, and the protective spring is deformed and accumulates force due to the squeezing of the tipping rack. After the tipping rack is out of contact with the tipping ring, the protective spring can drive the tipping rack to reset, and the tipping plate contacts the bottom of the inner wall of the cooling tank. The tipping rack moves back and forth vertically to flip the intermediate particles inside the cooling tank.

[0009] According to the above technical solution, it also includes a dredging module and an anti-backflow module. The dredging module is used to prevent intermediate particles from clogging and causing exhaust difficulties. The anti-backflow module is used to prevent condensed water from flowing back. The dredging module includes an air outlet pipe, a sealing plate, a separation frame, a separation plate, an elastic telescopic rod and a knocking ring. The separation frame can move back and forth to push the intermediate particles accumulated inside the air outlet pipe back into the cooling tank. The air outlet pipe is fixedly installed on the circumferential surface of the cooling tank, the sealing plate is fixedly installed on the inner wall of the air outlet pipe, the separation frame is slidably installed on the inner wall of the air outlet pipe, the separation plate is fixedly passed through the left and right walls of the separation frame, the elastic telescopic rod is fixedly installed on the left side of the sealing plate, and the knocking ring is fixedly installed on the inner wall of the air outlet pipe.

[0010] According to the above technical solution, the free end of the elastic telescopic rod is fixedly connected to the separation frame, and the left side of the separation plate is set as a slope. By setting the left side of the separation plate as a slope, the friction force when the separation plate contacts the tipping rack can be reduced. A knocking groove is opened on the inner wall of the knocking ring. The knocking groove can enhance the shaking effect of the knocking ring and the separation frame. When the separation frame moves to the right, it will contact the knocking ring and hit the knocking ring to generate shaking.

[0011] According to the above technical solution, the anti-backflow module includes an air outlet frame, an air outlet frame, a return spring, an air outlet, a sponge block and a drainage frame. The sponge block is deformed by the squeezing of the drainage frame, and the sponge block is deformed to squeeze out the condensed water adsorbed by itself. The air outlet frame slides through the left and right walls of the sealing plate, and the air outlet frame is fixedly installed on the top of the air outlet frame. The return spring is arranged between the air outlet frame and the sealing plate. The air outlet frame moves to the right to pull the return spring. The return spring is deformed and accumulates force by the pulling of the air outlet frame. After the air outlet frame is out of contact with the separation plate, the return spring can drive the air outlet frame to reset. The air outlet is opened at the top of the air outlet frame, the sponge block is fixedly installed on the top of the inner wall of the air outlet frame, and the drainage frame slides through the bottom of the air outlet frame.

[0012] According to the above technical solution, the anti-backflow module also includes a stabilizing rod and a drainage spring. The stabilizing rod is fixed through the circumferential surface of the air outlet pipe. The drainage spring is arranged between the drainage frame and the air outlet frame. The drainage frame moves upward to squeeze the drainage spring. The drainage spring is squeezed by the drainage frame to produce deformation and accumulate force. After the stabilizing rod is separated from the contact with the drainage frame, the drainage spring can drive the drainage frame to reset. A rubber ring is provided between the air outlet frame and the sealing plate. The rubber ring can increase the sealing between the air outlet frame and the sealing plate. The air outlet frame moves to the left to reset, which drives the air outlet frame to move to the left to reset. The air outlet frame moves back and forth to intermittently discharge the gas inside the cooling tank.

[0013] According to the above technical solution, the bottom of the drainage rack is set as an inclined surface, the drainage rack is in contact with the stabilizing rod, the sponge block is in conflict with the drainage rack, and a drain outlet is opened at the bottom of the air outlet frame. The condensed water squeezed out of the sponge block is discharged from the drain outlet under the action of its own gravity. A rubber strip is provided between the drainage rack and the air outlet frame, and the rubber strip can increase the sealing between the drainage rack and the air outlet frame.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] (1) This invention drives the turning plate to move slowly downward by slowly moving the turning rack downward. The turning plate moves slowly downward to prevent the turning plate from pressing the intermediate particles excessively. The slow-moving turning method can avoid compaction of the intermediate particles caused by excessive pressing while turning the particles, so that the particle layer remains loose, and the low-temperature cooling medium can smoothly penetrate the gaps between the particles, ensuring that the intermediate particles are cooled evenly. The turning rack is moved back and forth vertically to turn the intermediate particles inside the cooling tank, thereby increasing the contact area between the intermediate particles and the cold air. For sticky or easily agglomerated intermediate particles, the reciprocating vertical movement can reduce the adhesion between the intermediate particles through slight pulling and separation, thereby avoiding the intermediate particles from agglomerating and affecting the cooling uniformity.

[0016] (2) This invention prevents the intermediate particles from being adsorbed on the left side of the separation frame by moving the separation frame back and forth. Avoiding the adsorption of the intermediate particles can maintain the patency of the left side of the separation frame, prevent the intermediate particles from clogging the air outlet pipe and causing abnormal pressure in the cooling tank, thereby ensuring the stability of the cooling process. In addition, the shaking of the separation frame further loosens the intermediate particles, further ensuring smooth gas flow.

[0017] (3) This invention can push the intermediate particles accumulated inside the air outlet pipe back into the cooling tank by the reciprocating movement of the separation frame. Pushing the particles back into the cooling tank can avoid material waste and cross contamination. If the particles in the air outlet pipe are not recovered in time, they will deteriorate in the air outlet pipe, affecting the product yield. In addition, the intermediate particles pushed back into the cooling tank can continue to participate in the cooling process, ensuring full utilization of the material.

[0018] (4) In this invention, the sponge block continuously absorbs the condensed water inside the cooling tank under its own adsorption properties. When the air outlet frame moves to the right, the sponge block is squeezed by the drainage rack and deformed. The deformation of the sponge block squeezes out the condensed water adsorbed by itself and discharges it from the drain port. If the condensed water seeps back into the intermediate particles, it will cause the particles to become damp and clump together, reducing the purity of the product. By removing the condensed water in time through the sponge block to prevent the condensed water from flowing back, cross contamination can be avoided and impurity contamination caused by the condensed water can be reduced.

[0019] (5) In this invention, the air outlet rack moves to the left and resets, driving the air outlet frame to move to the left and reset. The air outlet frame moves back and forth to discharge the gas inside the cooling tank intermittently. Intermittent exhaust avoids the long-term impact of continuous airflow on the intermediate particle layer. If the gas is continuously discharged, a stable high-speed airflow will be formed in the cooling tank, which will easily carry the lightweight intermediate particles upward, causing the intermediate particles to be lost with the exhaust or attached to the tank wall. During intermittent exhaust, the airflow is only generated in a short time, and the exhaust rhythm is controlled by the reciprocating movement of the air outlet frame, which can maximize the stability of the intermediate particle layer and reduce material loss and subsequent cleaning costs. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0021] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0022] Figure 2 This is a schematic diagram of the half-section structure of the cooling tank of the present invention;

[0023] Figure 3 This is a schematic diagram of the position structure of the turning ring and the turning rack of the present invention;

[0024] Figure 4 This is a schematic diagram of a half-section structure of a hollow rod of the present invention;

[0025] Figure 5 This is a schematic diagram of a half-section structure of a separation frame of the present invention;

[0026] Figure 6 This is a schematic diagram of the half-section structure of the air outlet frame of the present invention;

[0027] Figure 7 It is a schematic diagram of the internal structure of the air outlet frame of the present invention.

[0028] In the figure: 1. Cooling tank; 2. Feed inlet; 3. Air inlet; 4. Discharge assembly; 5. Tipping rod; 6. Tipping ring; 7. Tipping rack; 8. Tipping plate; 9. Protective plate; 10. Protective spring; 11. Hollow rod; 12. Solid rod; 13. Shielding plate; 14. Air outlet; 151. Air outlet pipe; 152. Sealing plate; 153. Separation frame; 154. Separation plate; 155. Elastic telescopic rod; 156. Knocking ring; 161. Air outlet frame; 162. Air outlet rack; 163. Reset spring; 164. Air outlet; 165. Sponge block; 166. Drain rack; 167. Stabilizing rod; 168. Drain spring. DETAILED DESCRIPTION

[0029] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention. Example 1

[0030] See also Figure 1-7The present invention provides a technical solution: a rapid cooling device for the production of pharmaceutical intermediates, comprising a cooling tank 1 and an air cooling component, and also comprising a turning module. The top of the cooling tank 1 is provided with a feed port 2, the circumferential surface of the cooling tank 1 is provided with an air inlet 3, the bottom of the cooling tank 1 is provided with a discharge component 4, and the air cooling component is arranged on the left side of the cooling tank 1; the turning module comprises a turning rod 5, a turning ring 6, a turning rack 7, a turning plate 8, a protective plate 9, a hollow rod 11, a solid rod 12, a baffle 13 and an air outlet 14. The turning rod 5 rotates and passes through the top of the cooling tank 1, and the turning ring 6 is fixedly installed on the inner wall of the cooling tank 1. The frame 7 is slidably installed on the circumferential surface of the turning rod 5, the turning plate 8 is fixedly installed on the bottom of the turning frame 7, the protective plate 9 is fixedly installed on the circumferential surface of the turning rod 5, the hollow rod 11 is fixedly penetrated through the upper and lower walls of the protective plate 9, the solid rod 12 is slidably installed on the inner wall of the hollow rod 11, the baffle 13 is fixedly installed on the bottom of the inner wall of the hollow rod 11, and the air outlet 14 is opened at the bottom of the hollow rod 11. The slow-moving turning method can avoid the compaction of the intermediate particles caused by excessive pressing while turning the particles, so that the particle layer remains loose, so that the low-temperature cooling medium can smoothly penetrate the gap between the particles, and ensure that the intermediate particles are cooled evenly.

[0031] The top of the solid rod 12 is fixedly connected to the tipping rack 7, and a sealing ring is provided between the hollow rod 11 and the solid rod 12. The sealing ring can increase the sealing between the hollow rod 11 and the solid rod 12. The bottom of the tipping ring 6 is set to an arc surface. By setting the bottom of the tipping ring 6 to an arc surface, the friction force when the tipping ring 6 contacts the tipping rack 7 can be reduced.

[0032] The turning rack 7 is in conflict with the turning ring 6, and a protective spring 10 is provided between the protective plate 9 and the turning rack 7. The turning rack 7 moves downward to squeeze the protective spring 10. The protective spring 10 is squeezed by the turning rack 7 to deform and accumulate force. After the turning rack 7 is out of contact with the turning ring 6, the protective spring 10 can drive the turning rack 7 to reset, and the turning plate 8 contacts the bottom of the inner wall of the cooling tank 1. The turning rack 7 moves back and forth vertically to flip the intermediate particles inside the cooling tank 1. The reciprocating vertical movement can reduce the adhesion between the intermediate particles through slight pulling and separation, thereby avoiding the intermediate particles from agglomerating and affecting the cooling uniformity.

[0033] During operation, the intermediate particles to be cooled are put into the cooling tank 1 through the feed port 2. A servo motor is provided on the top of the cooling tank 1 and the output end of the servo motor is fixedly connected to the tipping rod 5. The rotation of the servo motor drives the tipping rod 5 to rotate counterclockwise, and the rotation of the tipping rod 5 drives the tipping rack 7 to rotate. The tipping rack 7 rotates and contacts the cambered surface of the tipping ring 6 and squeezes the tipping ring 6. The tipping rack 7 moves downward under the reaction force of the extrusion of the tipping ring 6. The downward movement of the tipping rack 7 drives the solid rod 12 to move downward. The downward movement of the solid rod 12 discharges the gas inside the hollow rod 11 into the interior of the cooling tank 1 through the air outlet 14. The gas inside the hollow rod 11 can only be slowly discharged into the interior of the cooling tank 1 through the air outlet 14. The gas can only be slowly discharged into the interior of the cooling tank 1 through the air outlet 14. The solid material is slowly discharged into the interior of the cooling tank 1, causing the solid rod 12 to move slowly downward. The solid rod 12 moves slowly downward, causing the flipping rack 8 to move slowly downward. The flipping plate 8 moves slowly downward to prevent the flipping plate 8 from excessively pressing on the intermediate particles. The servo motor continues to rotate to drive the flipping rod 5 to continue to rotate counterclockwise. The flipping rod 5 continues to rotate to drive the flipping rack 7 to continue to rotate. The flipping rack 7 continues to rotate to disengage from the arc surface contact with the flipping ring 6. After the flipping rack 7 is disengaged from the contact with the flipping ring 6, the flipping rack 7 moves upward under the elastic force of the protective spring 10. The flipping rack 7 moves downward, driving the flipping plate 8 to move upward and reset. The flipping rack 7 moves back and forth vertically to flip the intermediate particles inside the cooling tank 1, thereby increasing the contact area between the intermediate particles and the cold air. Example 2

[0034] See also Figure 1-7 153 , which prevents condensed water from flowing back.

[0035] The free end of the elastic telescopic rod 155 is fixedly connected to the separation frame 153, and the left side of the separation plate 154 is set as a slope. By setting the left side of the separation plate 154 as a slope, the friction force when the separation plate 154 contacts the turning rack 7 can be reduced, and a knocking groove is provided on the inner wall of the knocking ring 156. The knocking groove can enhance the shaking effect of the knocking ring 156 and the separation frame 153. When the separation frame 153 moves to the right, it will contact and hit the knocking ring 156 to generate shaking. Pushing the particles back to the cooling tank 1 can avoid material waste and cross contamination. If the particles in the air outlet pipe 151 are not recovered in time, they will deteriorate in the air outlet pipe 151, affecting the product yield, and the intermediate particles pushed back into the cooling tank 1 can continue to participate in the cooling process to ensure full utilization of the material.

[0036] The anti-backflow module includes an air outlet frame 161, an air outlet frame 162, a return spring 163, an air outlet 164, a sponge block 165 and a drainage frame 166. The air outlet frame 161 slides through the left and right walls of the sealing plate 152. The air outlet frame 162 is fixedly installed on the top of the air outlet frame 161. The return spring 163 is set between the air outlet frame 162 and the sealing plate 152. The air outlet frame 162 moves to the right to pull the return spring 163. The return spring 163 is affected by the air outlet frame 162. The pulling produces deformation and accumulates force. After the air outlet frame 161 is out of contact with the separation plate 154, the air outlet frame 162 can be driven to reset by the reset spring 163. The air outlet 164 is opened at the top of the air outlet frame 161, and the sponge block 165 is fixedly installed on the top of the inner wall of the air outlet frame 161. The drainage frame 166 slides through the bottom of the air outlet frame 161. The condensed water is removed in time by the sponge block 165 to prevent the condensed water from flowing back, which can avoid cross contamination and reduce impurity contamination caused by condensed water.

[0037] The anti-backflow module also includes a stabilizing rod 167 and a drainage spring 168. The stabilizing rod 167 is fixed through the circumferential surface of the air outlet pipe 151. The drainage spring 168 is arranged between the drainage frame 166 and the air outlet frame 161. The drainage frame 166 moves upward to squeeze the drainage spring 168. The drainage spring 168 is squeezed by the drainage frame 166 to produce deformation and accumulate force. After the stabilizing rod 167 is separated from the contact with the drainage frame 166, the drainage spring 168 can drive the drainage frame 166 to reset. A rubber ring is provided between the air outlet frame 161 and the sealing plate 152. The rubber ring can increase the sealing between the air outlet frame 161 and the sealing plate 152. The air outlet frame 162 moves to the left and resets, driving the air outlet frame 161 to move to the left and reset. The air outlet frame 161 reciprocates to discharge the gas inside the cooling tank 1 intermittently. During intermittent exhaust, the air flow is only generated in a short time, and the exhaust rhythm is controlled by the reciprocating movement of the air outlet frame 161, which can maximize the stability of the intermediate particle layer and reduce material loss and subsequent cleaning costs.

[0038] The bottom of the drainage frame 166 is set to be an inclined surface, the drainage frame 166 is in contact with the stabilizing rod 167, the sponge block 165 is in conflict with the drainage frame 166, and a drain outlet is opened at the bottom of the air outlet frame 161. The condensed water squeezed out by the sponge block 165 is discharged from the drain outlet under the action of its own gravity. A rubber strip is set between the drainage frame 166 and the air outlet frame 161, and the rubber strip can increase the sealing between the drainage frame 166 and the air outlet frame 161.

[0039] During operation, the tipping rack 7 rotates and contacts with the inclined surface of the separation plate 154 and squeezes the separation plate 154. The separation plate 154 moves to the right side under the squeezing of the tipping rack 7. The separation plate 154 moves to the right side and squeezes the free end of the elastic telescopic rod 155. The free end of the elastic telescopic rod 155 is squeezed by the separation plate 154 and moves to the right side and accumulates force. At the same time, the separation plate 154 moves to the right side, driving the separation frame 153 to move to the right side. When the servo motor continues to rotate, the tipping rod 5 continues to rotate counterclockwise. The tipping rod 5 continues to rotate and drives the tipping rack 7 to continue to rotate. The tipping rack 7 continues to rotate to disengage from the contact with the separation plate 154. When the tipping rack 7 disengages from After the separation plate 154 contacts, the separation plate 154 moves to the left and resets under the elastic force of the elastic telescopic rod 155. The separation plate 154 moves to the left and resets, driving the separation frame 153 to move to the left and reset. The separation frame 153 moves back and forth to prevent the intermediate particles from being adsorbed on the left side of the separation frame 153. At the same time, the separation frame 153 moves back and forth to push the intermediate particles accumulated inside the air outlet pipe 151 back into the cooling tank 1, and the separation frame 153 moves to the right and contacts the knocking ring 156 and hits the knocking ring 156 to cause shaking. The shaking of the separation frame 153 further loosens the intermediate particles and prevents the intermediate particles from being adsorbed on the left side of the separation frame 153.

[0040] The separation plate 154 moves to the right and contacts the air outlet frame 161 and squeezes the air outlet frame 161. The air outlet frame 161 is squeezed to the right by the separation plate 154, and the air outlet frame 161 moves to the right, driving the air outlet frame 162 to move to the right. The air outlet frame 161 moves to the right, causing the air outlet 164 to move to the right. The air outlet 164 moves to the right and is aligned with the sealing plate 152 and releases the seal on the air outlet pipe 151. After the seal of the air outlet pipe 151 is released, the gas inside the cooling tank 1 overflows through the air outlet 164, and the sponge block 165 continues to absorb the condensed water inside the cooling tank 1 under its own adsorption. When the air outlet frame 161 moves to the right, the air outlet frame 161 moves to the right and drives the drainage frame 166 to move to the right. The drainage frame 166 moves to the right and contacts the stabilizing rod 167 and squeezes the stabilizing rod 167. The drainage frame 166 moves upward under the reaction force of squeezing the stabilizing rod 167. The drain rack 166 moves upward to squeeze the sponge block 165, and the sponge block 165 is deformed by the squeezing of the drain rack 166. The sponge block 165 is deformed to squeeze out the condensed water adsorbed by itself, and the drain rack 166 moves upward to break away from the contact with the drain outlet and release the seal on the bottom of the air outlet frame 161. After the seal at the bottom of the air outlet frame 161 is released, the condensed water squeezed out of the sponge block 165 is discharged from the drain outlet under the action of its own gravity. When the separation plate 154 moves to the left and resets under the elastic force of the elastic telescopic rod 155, the separation plate 154 moves to the left and breaks away from the contact with the air outlet frame 161. After the air outlet frame 161 breaks away from the contact with the separation plate 154, the air outlet frame 162 moves to the left and resets under the elastic force of the reset spring 163. The air outlet frame 162 moves to the left and resets, driving the air outlet frame 161 to move to the left and reset. The air outlet frame 161 moves back and forth to intermittently discharge the gas inside the cooling tank 1.

[0041] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0042] Finally, it should be noted that the above are merely preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art will be able to modify the technical solutions described in the aforementioned embodiments or substitute equivalents for some of the technical features. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.

Claims

1. A rapid cooling device for producing pharmaceutical intermediates, comprising a cooling tank (1) and an air cooling assembly, characterized in that: It also includes a turning module, a dredging module and a backflow prevention module. The top of the cooling tank (1) is provided with a feed port (2), the circumferential surface of the cooling tank (1) is provided with an air inlet (3), the bottom of the cooling tank (1) is provided with a discharge assembly (4), and the air cooling assembly is provided on the left side of the cooling tank (1); The tipping module comprises a tipping rod (5), a tipping ring (6), a tipping rack (7), a tipping plate (8), a protective plate (9), a hollow rod (11), a solid rod (12), a shielding plate (13) and an air outlet (14), wherein the tipping rod (5) rotates and passes through the top of the cooling tank (1), the tipping ring (6) is fixedly mounted on the inner wall of the cooling tank (1), the tipping rack (7) is slidably mounted on the circumferential surface of the tipping rod (5), the tipping plate (8) is fixedly mounted on the bottom of the tipping rack (7), the protective plate (9) is fixedly mounted on the circumferential surface of the tipping rod (5), the hollow rod (11) is fixedly mounted through the upper and lower walls of the protective plate (9), the solid rod (12) is slidably mounted on the inner wall of the hollow rod (11), the shielding plate (13) is fixedly mounted on the bottom of the inner wall of the hollow rod (11), and the air outlet (14) is opened at the bottom of the hollow rod (11); The dredging module is used to prevent the intermediate particles from clogging and causing difficulty in exhausting, and the anti-backflow module is used to prevent the condensed water from flowing back; The dredging module comprises an air outlet pipe (151), a sealing plate (152), a separation frame (153), a separation plate (154), an elastic telescopic rod (155) and a knocking ring (156), wherein the air outlet pipe (151) is fixedly mounted on the circumferential surface of the cooling tank (1), the sealing plate (152) is fixedly mounted on the inner wall of the air outlet pipe (151), the separation frame (153) is slidably mounted on the inner wall of the air outlet pipe (151), the separation plate (154) is fixedly passed through the left and right walls of the separation frame (153), the elastic telescopic rod (155) is fixedly mounted on the left side of the sealing plate (152), and the knocking ring (156) is fixedly mounted on the inner wall of the air outlet pipe (151); The anti-backflow module comprises an air outlet frame (161), an air outlet rack (162), a return spring (163), an air outlet (164), a sponge block (165) and a drainage rack (166); the air outlet frame (161) slides through the left and right walls of the sealing plate (152); the air outlet rack (162) is fixedly installed on the top of the air outlet frame (161); the return spring (163) is arranged between the air outlet rack (162) and the sealing plate (152); the air outlet (164) is opened at the top of the air outlet frame (161); the sponge block (165) is fixedly installed on the top of the inner wall of the air outlet frame (161); and the drainage rack (166) slides through the bottom of the air outlet frame (161).

2. A rapid cooling device for producing pharmaceutical intermediates according to claim 1, characterized in that: The top of the solid rod (12) is fixedly connected to the tipping frame (7), a sealing ring is provided between the hollow rod (11) and the solid rod (12), and the bottom of the tipping ring (6) is provided as an arc surface.

3. A rapid cooling device for producing pharmaceutical intermediates according to claim 2, characterized in that: The tipping rack (7) contacts the tipping ring (6), a protection spring (10) is provided between the protection plate (9) and the tipping rack (7), and the tipping plate (8) contacts the bottom of the inner wall of the cooling tank (1).

4. The rapid cooling device for producing pharmaceutical intermediates according to claim 3, characterized in that: The free end of the elastic telescopic rod (155) is fixedly connected to the separation frame (153), the left side of the separation plate (154) is configured as an inclined surface, and a knocking groove is provided on the inner wall of the knocking ring (156).

5. The rapid cooling device for producing pharmaceutical intermediates according to claim 4, characterized in that: The backflow prevention module further comprises a stabilizing rod (167) and a drainage spring (168), wherein the stabilizing rod (167) is fixedly passed through the circumferential surface of the air outlet pipe (151), and the drainage spring (168) is arranged between the drainage frame (166) and the air outlet frame (161), and a rubber ring is arranged between the air outlet frame (161) and the sealing plate (152).

6. A rapid cooling device for producing pharmaceutical intermediates according to claim 5, characterized in that: The bottom of the drainage frame (166) is set as an inclined surface, the drainage frame (166) contacts the stabilizing rod (167), the sponge block (165) conflicts with the drainage frame (166), a drainage port is opened at the bottom of the air outlet frame (161), and a rubber strip is set between the drainage frame (166) and the air outlet frame (161).

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