Whitening, anti-aging and skin-care composition as well as preparation method and application thereof

Abstract

The invention relates to the technical field of skin care products, and particularly discloses a whitening, anti-aging and skin care composition as well as a preparation method and application thereof. The whitening, anti-aging and skin-care composition is prepared from the following components in parts by mass: 1 to 3 parts of maugreek palm wood (MAURITIAFLEXUOSA fruit oil, 0.1 to 0.5 part of euglena gracilis (EUGLENA GRACILIS) polysaccharide, 0.5 to 2 parts of phytosterol substances, 1 to 3 parts of chitosan substances and 0.1 to 1 part of blue copper peptide. According to the skin-care composition disclosed by the invention, the rumex mairei fruit oil, the euglena gracilis polysaccharide, the phytosterol substances, the chitosan substances and the blue copper peptide are compounded according to a specific proportion, and all the components have a synergistic effect, so that the oxidation resistance, the light aging resistance and the repairing effect of the skin-care composition can be remarkably improved.

Description

Technical Field

[0001] The present invention relates to the technical field of skin care products, and particularly discloses a whitening and anti-aging skin care composition and a preparation method thereof. Background Art

[0002] As living standards improve, demand for effective skincare products is also increasing. Whitening and anti-aging are two key benefits that consumers are most interested in. Whitening skincare products primarily improve uneven skin tone and dark spots by inhibiting melanin production, blocking melanin transport, and accelerating melanin metabolism. Anti-aging skincare products focus on addressing skin aging issues such as dryness and dehydration, collagen loss, increased wrinkles, and sagging skin.

[0003] However, most whitening and anti-aging skincare products currently on the market primarily target melanin removal to achieve a whitening effect, or increase moisturizing properties in the hope of quickly hydrating the skin to plump up fine lines and achieve an anti-aging effect. However, these products often only address surface skin issues and fail to fundamentally improve skin condition. In particular, they overlook the damage caused to the skin by photoaging. Photoaging refers to a series of aging phenomena caused by long-term exposure to ultraviolet radiation, including rough skin, deeper wrinkles, hyperpigmentation, and sagging skin. Some existing whitening and anti-aging skincare products have limited effectiveness in protecting against photoaging and fail to fully protect against UV damage to the skin. Therefore, it is crucial to develop a whitening and anti-aging skincare product that can effectively combat photoaging and comprehensively protect the skin from UV damage. Summary of the Invention

[0004] The purpose of the present invention is to overcome the deficiencies of the prior art and provide a whitening and anti-aging skin care composition and a preparation method thereof.

[0005] In a first aspect, the present invention discloses a whitening and anti-aging skin care composition, which adopts the following technical solution:

[0006] A whitening and anti-aging skin care composition, comprising the following components in parts by mass:

[0007]

[0008]

[0009] The present invention combines multiple ingredients: MAURITIA FLEXUOSA fruit oil and Euglena gracilisis polysaccharides to jointly exert anti-aging and repair effects; phytosterols and chitosan strengthen the skin barrier and moisturizing function; and blue copper peptides enhance the overall anti-aging effect and promote skin regeneration. Among them, MAURITIA FLEXUOSA fruit oil is rich in natural vitamin E, carotenoids (such as β-carotene), unsaturated fatty acids, etc., has strong antioxidant capacity and good permeability, can protect collagen, reduce fine lines and wrinkles, and enhance skin elasticity. Euglena gracilisis polysaccharides have anti-inflammatory activity, can inhibit leukocyte elastase, promote collagen synthesis, and help improve skin firmness and elasticity. The structure of phytosterols is similar to that of cholesterol in human sebum, and can penetrate the stratum corneum, repair damaged lipid barriers, and alleviate problems such as sensitivity. Chitosan substances have good biocompatibility and film-forming properties, can form a protective film on the skin surface, lock in moisture, and have certain antibacterial and repair effects. Blue copper peptide is a small molecule peptide that can stimulate skin regeneration, reduce wrinkles, improve skin firmness, and also has antioxidant and anti-inflammatory effects.

[0010] Preferably, the mass ratio of the MAURITIA FLEXUOSA fruit oil to the EUGLENA GRACILIS polysaccharide is 4.0 to 4.8.

[0011] As a lipid component, euglena fruit oil helps other active ingredients penetrate deeper into the skin. At this ratio, euglena polysaccharides form a complex with euglena fruit oil, promoting the absorption of skincare ingredients. This specific ratio of euglena polysaccharides helps improve the bioavailability of other active ingredients in skincare compositions, such as phytosterols and copper peptides, thereby enhancing the effectiveness of the overall skincare formula.

[0012] Preferably, the phytosterols include one or more combinations of stigmasterol, β-sitosterol, and campesterol.

[0013] The stanol esters contained in phytosterols have excellent water-control properties and have a good moisturizing effect on the skin. They can maintain moisture on the skin surface, promote the production of new collagen, and promote metabolism, thereby preventing the appearance of skin sensitivity and aging characteristics. The phytosterol substance is preferably stigmasterol. Compared with β-sitosterol and campesterol, stigmasterol has a double bond at the C-22 position. The presence of the double bond at the C-22 position makes stigmasterol more likely to react with free radicals, thereby enhancing its antioxidant capacity. This antioxidant effect helps protect the skin from damage caused by oxidative stress and delays the aging process of the skin. The double bond also increases the fluidity of the stigmasterol molecule in the cell membrane, making it more permeable to the skin, which can improve the structure and function of the skin barrier and enhance the skin's moisturizing ability.

[0014] Preferably, the chitosan-based substance comprises a combination of one or more of carboxymethyl chitosan and quaternary ammonium chitosan. Carboxymethyl chitosan has better water solubility and biocompatibility than ordinary chitosan, while quaternary ammonium chitosan has better antibacterial properties and biological activity. In addition, quaternary ammonium chitosan has strong polycationic properties and can enhance the permeability of cell membranes, which helps stigmasterol to more easily penetrate the skin barrier and enter the skin cells, thereby better exerting its anti-oxidation, cell repair and other anti-aging functions.

[0015] Preferably, the chitosan substance is deacetylated chitosan with a deacetylation degree of 80 to 90%.

[0016] Deacetylated chitosan has excellent hygroscopicity and moisturizing properties, absorbing moisture from the air to provide long-lasting moisturization. It can promote skin cell metabolism, accelerate the repair process of damaged skin, and improve skin texture. Free amino groups are key to chitosan's antioxidant activity. If the degree of deacetylation is low, these groups are fewer, making it difficult for them to effectively bind free fatty acids, resulting in a weaker antioxidant capacity and inability to effectively prevent lipid oxidation. However, if the degree of deacetylation is too high, the chitosan molecule's hygroscopicity and moisturizing properties become excessive, potentially leading to overhydration of the skin, weakening the skin's barrier function and making it more susceptible to external irritation and damage. Both excessive and low deacetylation levels are detrimental to the optimal performance of chitosan. Experimental studies have shown that a deacetylation degree of 80% to 90% achieves a balance of properties, making it ideal for use in skincare products.

[0017] Preferably, the following components are included in parts by mass:

[0018]

[0019] In a second aspect, the present invention discloses a method for preparing a whitening and anti-aging skin care composition, comprising the following steps:

[0020] MAURITIA FLEXUOSA fruit oil and phytosterols are mixed at 80-85°C, then cooled to 45±3°C, and then EUGLENA GRACILIS polysaccharide, chitosan and blue copper peptide are added and mixed to obtain a whitening and anti-aging skin care composition.

[0021] In a third aspect, the present invention discloses an application of a whitening and anti-aging skin care composition in skin care products. The skin care products include the whitening and anti-aging skin care composition and auxiliary materials. The addition amount of the whitening and anti-aging skin care composition is 2 to 20 wt%.

[0022] Preferably, the skin care product is a facial cream, which comprises the following components in parts by mass:

[0023]

[0024] Preferably, the solvent comprises a combination of one or more of water, butylene glycol, and propylene glycol;

[0025] The moisturizing agent includes one or more combinations of glycerin, sodium hyaluronate, sodium lactate, sodium polyglutamate, sodium stearoyl glutamate, β-glucan, fructose, carbohydrate hydrolyzate, carbomer, collagen, hydrolyzed collagen, and glycoprotein;

[0026] The emollient includes one or more combinations of caprylic / capric triglyceride, glyceryl stearate, polyglyceryl-10 oleate, polysorbate-20, glyceryl caprylate, hydrogenated lecithin, and phosphatidylcholine;

[0027] The antioxidant includes one or more combinations of hydroxypropyl tetrahydropyrantriol, p-hydroxyacetophenone, and tocopheryl acetate;

[0028] The skin conditioning agent includes a combination of one or more of cynanchum atratum extract, licorice root extract, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, decapeptide-4, ceramide NP, and bisabolol.

[0029] Compared with the prior art, the present invention has at least the following beneficial effects:

[0030] The present invention combines palm oil, fine algae polysaccharides, phytosterols, chitosans, and blue copper peptides in specific proportions, and the synergistic effect of each component can significantly enhance the antioxidant, anti-photoaging, and repair effects of the skin care composition. Palm oil is rich in natural antioxidants and can effectively scavenge free radicals, protect collagen, and reduce fine lines and wrinkles; fine algae polysaccharides have anti-inflammatory activity and can promote collagen synthesis, improving skin firmness and elasticity; phytosterols can penetrate the stratum corneum, repair damaged lipid barriers, and relieve sensitivity; chitosans have good biocompatibility and film-forming properties, can form a protective film on the skin surface, lock in moisture, and have antibacterial and repair effects; blue copper peptides can stimulate skin regeneration, reduce wrinkles, and improve skin firmness. Through the synergistic effect of multiple ingredients, the composition comprehensively improves skin texture, enhances skin barrier function, and achieves the multiple effects of whitening, anti-aging, and repair. DETAILED DESCRIPTION

[0031] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below in conjunction with specific embodiments.

[0032] Example 1

[0033] A whitening and anti-aging skin care composition, comprising the following components in parts by mass:

[0034] 1.2 parts of MAURITIA FLEXUOSA fruit oil, 0.27 parts of EUGLENAGRACILIS polysaccharide, 0.7 parts of phytosterols, 3 parts of chitosans, and 0.2 parts of blue copper peptide.

[0035] Euglena gracilis polysaccharide was purchased from Yuzhi Biochemical Technology Co., Ltd.; Mauritia flexuosa fruit oil was purchased from CITROBIO; and blue copper peptide was purchased from Dongguan Weiqi Technology Co., Ltd. The ingredients mentioned in the following examples are all commercially available products and are not described in detail here. The phytosterols were specifically stigmasterol; and the chitosan was specifically quaternary ammonium chitosan with an 85% degree of deacetylation.

[0036] The preparation method of the whitening and anti-aging skin care composition is as follows:

[0037] MAURITIA FLEXUOSA fruit oil and phytosterols are placed in a homogenizer, heated to 80-85°C while stirring, and after being evenly mixed, cooled to 45±3°C. Euglena gracilis polysaccharide, chitosan and blue copper peptide are added, and the mixture is kept warm and stirred to mix evenly to obtain a whitening and anti-aging skin care composition.

[0038] Example 2

[0039] A whitening and anti-aging skin care composition, comprising the following components in parts by mass:

[0040] 1.5 parts of MAURITIA FLEXUOSA fruit oil, 0.2 parts of EUGLENAGRACILIS polysaccharide, 0.7 parts of phytosterols, 3 parts of chitosans, and 0.2 parts of blue copper peptide.

[0041] The phytosterol substance is specifically stigmasterol; and the chitosan substance is specifically quaternary ammonium salt chitosan with a deacetylation degree of 85%.

[0042] The preparation method of the whitening and anti-aging skin care composition is as follows:

[0043] MAURITIA FLEXUOSA fruit oil and phytosterols are placed in a homogenizer, heated to 80-85°C while stirring, and after being evenly mixed, cooled to 45±3°C. Euglena gracilis polysaccharide, chitosan and blue copper peptide are added, and the mixture is kept warm and stirred to mix evenly to obtain a whitening and anti-aging skin care composition.

[0044] Example 3

[0045] A whitening and anti-aging skin care composition, comprising the following components in parts by mass:

[0046] 1 part of MAURITIA FLEXUOSA fruit oil, 0.4 parts of EUGLENA GRACILIS polysaccharide, 0.7 parts of phytosterols, 3 parts of chitosans, and 0.2 parts of blue copper peptide.

[0047] The phytosterol substance is specifically stigmasterol; and the chitosan substance is specifically quaternary ammonium salt chitosan with a deacetylation degree of 85%.

[0048] The preparation method of the whitening and anti-aging skin care composition is as follows:

[0049] MAURITIA FLEXUOSA fruit oil and phytosterols are placed in a homogenizer, heated to 80-85°C while stirring, and after being evenly mixed, cooled to 45±3°C. Euglena gracilis polysaccharide, chitosan and blue copper peptide are added, and the mixture is kept warm and stirred to mix evenly to obtain a whitening and anti-aging skin care composition.

[0050] Example 4

[0051] A whitening and anti-aging skin care composition, comprising the following components in parts by mass:

[0052] 1.2 parts of MAURITIA FLEXUOSA fruit oil, 0.27 parts of EUGLENAGRACILIS polysaccharide, 0.7 parts of phytosterols, 3 parts of chitosans, and 0.2 parts of blue copper peptide.

[0053] The phytosterol substance is specifically β-sitosterol; and the chitosan substance is specifically quaternary ammonium salt chitosan with a deacetylation degree of 85%.

[0054] The preparation method of the whitening and anti-aging skin care composition is as follows:

[0055] MAURITIA FLEXUOSA fruit oil and phytosterols are placed in a homogenizer, heated to 80-85°C while stirring, and after being evenly mixed, cooled to 45±3°C. Euglena gracilis polysaccharide, chitosan and blue copper peptide are added, and the mixture is kept warm and stirred to mix evenly to obtain a whitening and anti-aging skin care composition.

[0056] Example 5

[0057] A whitening and anti-aging skin care composition, comprising the following components in parts by mass:

[0058] 1.2 parts of MAURITIA FLEXUOSA fruit oil, 0.27 parts of EUGLENAGRACILIS polysaccharide, 0.7 parts of phytosterols, 3 parts of chitosans, and 0.2 parts of blue copper peptide.

[0059] The phytosterol substance is specifically campesterol; and the chitosan substance is specifically quaternary ammonium salt chitosan with a deacetylation degree of 85%.

[0060] The preparation method of the whitening and anti-aging skin care composition is as follows:

[0061] MAURITIA FLEXUOSA fruit oil and phytosterols are placed in a homogenizer, heated to 80-85°C while stirring, and after being evenly mixed, cooled to 45±3°C. Euglena gracilis polysaccharide, chitosan and blue copper peptide are added, and the mixture is kept warm and stirred to mix evenly to obtain a whitening and anti-aging skin care composition.

[0062] Example 6

[0063] A whitening and anti-aging skin care composition, comprising the following components in parts by mass:

[0064] 1.2 parts of MAURITIA FLEXUOSA fruit oil, 0.27 parts of EUGLENAGRACILIS polysaccharide, 0.7 parts of phytosterols, 3 parts of chitosans, and 0.2 parts of blue copper peptide.

[0065] The phytosterol substance is specifically stigmasterol; and the chitosan substance is specifically carboxymethyl chitosan with a deacetylation degree of 85%.

[0066] The preparation method of the whitening and anti-aging skin care composition is as follows:

[0067] MAURITIA FLEXUOSA fruit oil and phytosterols are placed in a homogenizer, heated to 80-85°C while stirring, and after being evenly mixed, cooled to 45±3°C. Euglena gracilis polysaccharide, chitosan and blue copper peptide are added, and the mixture is kept warm and stirred to mix evenly to obtain a whitening and anti-aging skin care composition.

[0068] Example 7

[0069] A whitening and anti-aging skin care composition, comprising the following components in parts by mass:

[0070] 1.2 parts of MAURITIA FLEXUOSA fruit oil, 0.27 parts of EUGLENAGRACILIS polysaccharide, 0.7 parts of phytosterols, 3 parts of chitosans, and 0.2 parts of blue copper peptide.

[0071] The phytosterol substance is specifically stigmasterol; and the chitosan substance is specifically quaternary ammonium salt chitosan with a deacetylation degree of 95%.

[0072] The preparation method of the whitening and anti-aging skin care composition is as follows:

[0073] MAURITIA FLEXUOSA fruit oil and phytosterols are placed in a homogenizer, heated to 80-85°C while stirring, and after being evenly mixed, cooled to 45±3°C. Euglena gracilis polysaccharide, chitosan and blue copper peptide are added, and the mixture is kept warm and stirred to mix evenly to obtain a whitening and anti-aging skin care composition.

[0074] Example 8

[0075] A whitening and anti-aging skin care composition, comprising the following components in parts by mass:

[0076] 1.2 parts of MAURITIA FLEXUOSA fruit oil, 0.27 parts of EUGLENAGRACILIS polysaccharide, 0.7 parts of phytosterols, 3 parts of chitosans, and 0.2 parts of blue copper peptide.

[0077] The phytosterol substance is specifically stigmasterol; and the chitosan substance is specifically quaternary ammonium salt chitosan with a deacetylation degree of 75%.

[0078] The preparation method of the whitening and anti-aging skin care composition is as follows:

[0079] MAURITIA FLEXUOSA fruit oil and phytosterols are placed in a homogenizer, heated to 80-85°C while stirring, and after being evenly mixed, cooled to 45±3°C. Euglena gracilis polysaccharide, chitosan and blue copper peptide are added, and the mixture is kept warm and stirred to mix evenly to obtain a whitening and anti-aging skin care composition.

[0080] Example 9

[0081] A whitening and anti-aging skin care composition, comprising the following components in parts by mass:

[0082] 3 parts of MAURITIA FLEXUOSA fruit oil, 0.7 parts of EUGLENA GRACILIS polysaccharide, 1 part of phytosterols, 1 part of chitosan, and 0.1 part of blue copper peptide.

[0083] Among them, Euglena gracilis polysaccharide was purchased from Yuzhi Biochemical Technology Co., Ltd.; Mauritia flexuosa fruit oil was purchased from CITROBIO; and blue copper peptide was purchased from Dongguan Weiqi Technology Co., Ltd. The ingredients mentioned in the following examples are all commercially available products and are not described in detail. The phytosterol substance is specifically stigmasterol; the chitosan substance is specifically a quaternary ammonium chitosan with a deacetylation degree of 85%.

[0084] The preparation method of the whitening and anti-aging skin care composition is as follows:

[0085] MAURITIA FLEXUOSA fruit oil and phytosterols are placed in a homogenizer, heated to 80-85°C while stirring, and after being evenly mixed, cooled to 45±3°C. Euglena gracilis polysaccharide, chitosan and blue copper peptide are added, and the mixture is kept warm and stirred to mix evenly to obtain a whitening and anti-aging skin care composition.

[0086] Example 10

[0087] A whitening and anti-aging skin care composition, comprising the following components in parts by mass:

[0088] 2 parts of MAURITIA FLEXUOSA fruit oil, 0.5 parts of EUGLENA GRACILIS polysaccharide, 0.5 parts of phytosterols, 2 parts of chitosan, and 0.1 parts of blue copper peptide.

[0089] Among them, Euglena gracilis polysaccharide was purchased from Yuzhi Biochemical Technology Co., Ltd.; Mauritia flexuosa fruit oil was purchased from CITROBIO; and blue copper peptide was purchased from Dongguan Weiqi Technology Co., Ltd. The ingredients mentioned in the following examples are all commercially available products and are not described in detail. The phytosterol substance is specifically stigmasterol; the chitosan substance is specifically a quaternary ammonium chitosan with a deacetylation degree of 85%.

[0090] The preparation method of the whitening and anti-aging skin care composition is as follows:

[0091] MAURITIA FLEXUOSA fruit oil and phytosterols are placed in a homogenizer, heated to 80-85°C while stirring, and after being evenly mixed, cooled to 45±3°C. Euglena gracilis polysaccharide, chitosan and blue copper peptide are added, and the mixture is kept warm and stirred to mix evenly to obtain a whitening and anti-aging skin care composition.

[0092] Comparative Example 1

[0093] The difference from Example 1 is that the MAURITIA FLEXUOSA fruit oil is replaced by an equal amount of 85% deacetylated quaternary ammonium salt chitosan.

[0094] Comparative Example 2

[0095] The difference from Example 1 is that the polysaccharide of Euglena gracilis is replaced by an equal amount of 85% deacetylated quaternary ammonium salt chitosan.

[0096] Comparative Example 3

[0097] The difference from Example 1 is that an equal amount of 85% deacetylated quaternary ammonium chitosan is used instead of stigmasterol.

[0098] Comparative Example 4

[0099] The difference from Example 1 is that an equal amount of 85% deacetylated quaternary ammonium salt chitosan is used instead of blue copper peptide.

[0100] Comparative Example 5

[0101] The difference from Example 1 is that it only contains 85% deacetylated quaternary ammonium salt chitosan.

[0102] Experiment 1

[0103] Purpose of the experiment: HacaT cells (human immortalized keratinocytes) are a common and effective in vitro experimental method. The whitening and anti-aging skin care composition's anti-ultraviolet damage effect is detected based on HacaT cells to verify that the whitening and anti-aging skin care composition can effectively slow down the aging effect of anti-ultraviolet rays on the skin.

[0104] Experimental methods:

[0105] (1) Cell culture and treatment

[0106] HaCaT cells were cultured in DMEM medium (containing 10% fetal bovine serum and 1% penicillin-streptomycin). After the cells grew to the logarithmic phase, they were digested and seeded into 96-well culture plates at a density of 8×10 4 After culturing for 24 hours, the culture medium in the plate was discarded and washed twice with PBS. The culture medium of the following groups was replaced and continued to be cultured.

[0107] (2) Group design

[0108] Blank control group: DMEM medium without the composition, normal culture, and no UV treatment.

[0109] UV model group: DMEM medium without the composition, UV treatment.

[0110] Component experimental group: DMEM culture medium containing 1% of the corresponding composition in Examples 1-10 or Comparative Examples 1-5, and treated with UV.

[0111] Positive control group: DMEM medium containing vitamin C (1 μg / mL), UV treatment.

[0112] (3) Ultraviolet radiation

[0113] After culturing for 12 h, the culture medium of the corresponding group was replaced with PBS culture medium and irradiated with UVA light source at a dose of 20 J / cm 2 , the irradiation time is 20min.

[0114] (4) Detection of cell survival rate

[0115] After irradiation, the culture medium was replaced with DMEM. After further culture for 24 h, the cells were collected and the cell survival rate was detected by MTT method. 10 μL of MTT solution (concentration 5 mg / mL) was added to each well and culture was continued for 4 h. After aspirating the culture medium in the wells, 100 μL of DMSO was added to each well and the wells were placed on a shaker for low-speed shaking for 10 min. The absorbance value (OD value) of each well was measured at a wavelength of 570 nm using a microplate reader to calculate the cell survival rate of each group.

[0116] Cell survival rate (%) = (OD component experimental group - OD background) / OD blank control group x 100%

[0117] The test results are shown in Table 1.

[0118] Table 1

[0119] Group Cell survival rate (%) UV model group 45.2 Example 1 96.2 Example 2 89.5 Example 3 88.7 Example 4 80.4 Example 5 86.3 Example 6 83.8 Example 7 91.5 Example 8 90.9 Example 9 92.6 Example 10 94.8 Comparative Example 1 63.3 Comparative Example 2 66.2 Comparative Example 3 64.3 Comparative Example 4 67.7 Comparative Example 5 57.1 Positive control group 63.4

[0120] As can be seen from the test data in Table 1, the cells in the UV model group had a low cell survival rate under ultraviolet irradiation, while the cells in the culture medium containing the composition of Examples 1-10 significantly improved the cell survival rate under ultraviolet irradiation. This shows that the composition formula of this scheme has a good anti-aging effect on skin cells, and specifically resists the aging damage to the skin caused by photoaging.

[0121] Comparison of the results of Example 1 with those of Examples 4-5 shows that stigmasterol, a phytosterol, has a better UV protection effect on cells than β-sitosterol and campesterol. Comparison of the results of Example 1 with those of Examples 6-8 shows that quaternary ammonium chitosan, a chitosan, has a better effect than carboxymethyl chitosan. Furthermore, when the degree of deacetylation is within a specific range, chitosan can maximize its synergistic effect with other components. Comparison of the test results of Examples 1-3 with those of Examples 9-10 shows that when the mass ratio of MAURITIA FLEXUOSA fruit oil to EUGLENA GRACILIS polysaccharide is within a certain range, a more effective synergistic effect is achieved.

[0122] From the comparison of the results of Comparative Examples 1-5 with Example 1, it can be seen that the whitening and anti-aging skin care composition of this scheme has an excellent cell protection against ultraviolet damage due to the synergistic effect brought about by the mutual cooperation and mutual complementation of the ingredients of MAURITIA FLEXUOSA fruit oil, EUGLENA GRACILIS polysaccharide, phytosterols, chitosans and blue copper peptides, all of which are indispensable and together play a role in enhancing the photoaging protection of skin cells.

[0123] Application Example 1

[0124] A whitening and anti-aging facial cream, comprising the following components in parts by mass:

[0125] Whitening and anti-aging skin care composition: 5.37 wt% of the composition prepared in Example 1;

[0126] Moisturizer: glycerol 2.71wt%, sodium hyaluronate 0.15wt%, sodium lactate 0.05wt%, sodium polyglutamate 0.1wt%, sodium stearoyl glutamate 0.0025wt%, β-glucan 0.024wt%, fructose 0.1wt%, carbohydrate hydrolyzate 0.08wt%, carbomer 0.05wt%, collagen 0.2wt%, hydrolyzed collagen 0.03wt%, glycoprotein 0.0002wt%;

[0127] Emollients: caprylic / capric triglyceride 1.84wt%, glyceryl stearate 0.24wt%, polyglyceryl-10 oleate 0.01wt%, polysorbate-20 0.025wt%, glyceryl caprylate 0.015wt%, hydrogenated lecithin 0.004wt%, phosphatidylcholine 0.025wt%;

[0128] Antioxidants: 0.45 wt% hydroxypropyl tetrahydropyrantriol, 0.05 wt% p-hydroxyacetophenone, 0.3 wt% tocopheryl acetate;

[0129] Skin conditioning agents: Cynachum atratum extract 0.01wt%, Glycyrrhiza uralensis root extract 0.001wt%, Palmitoyl tripeptide-10.0005wt%, Palmitoyl tetrapeptide-70.00025wt%, Decapeptide-40.0002wt%, Ceramide NP 0.015wt%, Bisabolol 0.01wt%;

[0130] Preservatives: phenoxyethanol 0.05 wt%, ethylhexylglycerin 0.004 wt%, caprylhydroxamic acid 0.046 wt%.

[0131] Solvent: 2.4 wt% of butanediol, 0.74 wt% of propylene glycol, and the balance is water.

[0132] The preparation method of the whitening and anti-aging cream is as follows:

[0133] S1. Put the water in the solvent into the emulsifying pot, stir it (20r / min), heat the water to 80-85°C, add the remaining components of the solvent into the emulsifying pot, homogenize it (2000r / min) for 5 minutes, and then keep it warm for 10 minutes while stirring (20r / min);

[0134] S2. Pour the emollient into the oil pan, raise the temperature to 80-85°C while stirring (30r / min), and then pump the emollient into the emulsifying pot to mix with the solvent.

[0135] S3. After the solvent and emollient are mixed, homogenize at 3000 rpm for 10 min, evacuate to -0.05 MPa and hold for 1 min before stopping; continue stirring at 20 rpm to cool down;

[0136] S4. Cool down to 45±3°C, add the raw materials of the whitening and anti-aging skin care composition, moisturizer, antioxidant, skin conditioner, and preservative, and stir thoroughly (3000 rpm) for 5 minutes.

[0137] S5. Take samples and filter the material with 100 mesh filter cloth after passing the inspection.

[0138] Application Examples 2 to 15

[0139] The preparation method is the same as that of Application Example 1, except that the whitening and anti-aging skin care composition is different, as shown in Table 2.

[0140] Table 2

[0141]

[0142]

[0143] Experiment 2

[0144] Experimental purpose: To verify the whitening and anti-aging effect of a whitening and anti-aging cream containing a whitening and anti-aging skin care composition on the skin of volunteers.

[0145] Experimental Method: A clinical trial was conducted on human skin using the experimental sample cream to test its irritation and whitening and anti-aging effects. A total of 160 subjects aged 40 to 60 with dry lines, fine lines, or wrinkles were selected. They had not recently used other functional skincare products and were divided into 16 groups. Each group was treated with a different experimental sample cream. The subjects in each group were similar in terms of gender, age, and skin tone.

[0146] Experimental samples: The whitening and anti-aging creams prepared in Application Examples 1-15 and common moisturizing creams available on the market were used as 16 experimental samples and distributed to 16 groups of volunteers for use.

[0147] Directions:

[0148] The subjects used the corresponding products during the day and night after cleaning their faces every morning and evening, for a period of 3 weeks.

[0149] Effect evaluation method:

[0150] Using the VISIA skin analyzer, participants' facial skin was examined for wrinkles, brown spots, and pores before and three weeks after the experiment. The VISIA system calculated scores, with higher scores indicating more severe issues. The percentage decrease (%) in each participant's score before and after use represented the degree of improvement in each skin condition. The percentage decrease in VISIA scores for each group of volunteers using the different experimental cream samples was calculated as the truncated mean. The statistical results are shown in Table 3.

[0151] Table 3

[0152]

[0153]

[0154] As can be seen from the skin test results in the table above, after three weeks of use, the whitening and anti-aging cream application examples 1-10 containing the whitening and anti-aging skin care composition of this patent have different degrees of improvement effects on skin wrinkles, brown spots and pores, and the anti-aging effect is significantly better than that of ordinary moisturizing cream products available on the market.

[0155] Among them, Application Example 1 achieved the most significant improvement, with wrinkle improvement reaching 18.73%, brown spot improvement reaching 10.51%, and pore improvement reaching 7.83%. This demonstrates that the composition has excellent comprehensive effects in whitening, anti-aging, and pore refinement. Application Examples 2-10 also demonstrated varying degrees of improvement, with wrinkle improvement ranging from 12.92% to 16.62%, brown spot improvement ranging from 7.45% to 9.93%, and pore improvement ranging from 5.31% to 7.35%. This demonstrates that the composition of the present invention can achieve excellent skin care effects at different formulation ratios.

[0156] In comparison, the improvement effects of Application Examples 11-15 (Comparative Examples 1-5) were poor, with the degree of wrinkle improvement being only 6.95%-8.91%, the degree of brown spot improvement being between 0.52%-2.29%, and the degree of pore improvement being between 0.82%-2.62%, which were significantly lower than those of Application Examples 1-10. This further demonstrates that the synergistic effect of palm oil, fine algae polysaccharides, phytosterols, chitosans, and blue copper peptides in the present invention is the key to achieving excellent skin care effects.

[0157] The technical solution provided by the present invention is introduced in detail above. Specific examples are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea. At the same time, for those skilled in the art, according to the idea of ​​the present invention, there may be changes in the specific implementation methods and application scope. In summary, the content of this specification should not be understood as limiting the present invention.

Claims

1. A whitening and anti-aging skin care composition, characterized in that: Calculated by mass, it includes the following components:

2. The whitening and anti-aging skin care composition according to claim 1, characterized in that: The mass ratio of MAURITIA FLEXUOSA fruit oil to EUGLENA GRACILIS polysaccharide is 4.0-4.

8.

3. The whitening and anti-aging skin care composition according to claim 1, characterized in that: The plant sterols include one or more combinations of stigmasterol, β-sitosterol, and campesterol.

4. The whitening and anti-aging skin care composition according to claim 1, characterized in that: The chitosan material includes one or more combinations of carboxymethyl chitosan and quaternary ammonium salt chitosan.

5. The whitening and anti-aging skin care composition according to claim 1, characterized in that: The chitosan substance is deacetylated chitosan with a deacetylation degree of 80-90%.

6. The whitening and anti-aging skin care composition according to claim 1, characterized in that: Calculated by mass, it includes the following components:

7. A method for preparing the whitening and anti-aging skin care composition according to any one of claims 1 to 6, characterized in that: The following steps are involved: MAURITIA FLEXUOSA fruit oil and phytosterols are mixed at 80-85°C, then cooled to 45±3°C, and then EUGLENA GRACILIS polysaccharide, chitosan and blue copper peptide are added and mixed to obtain a whitening and anti-aging skin care composition.

8. Application of a whitening and anti-aging skin care composition in skin care products, characterized in that: The skin care product comprises the whitening and anti-aging skin care composition according to any one of claims 1 to 6 and auxiliary materials, and the addition amount of the whitening and anti-aging skin care composition is 2 to 20 wt %.

9. Use of the whitening and anti-aging skin care composition according to claim 1 in skin care products, characterized in that: The skin care product is a facial cream, which comprises the following components in parts by mass:

10. Use of the whitening and anti-aging skin care composition according to claim 1 in skin care products, characterized in that: The solvent includes one or more combinations of water, butylene glycol, and propylene glycol; The moisturizing agent includes one or more combinations of glycerin, sodium hyaluronate, sodium lactate, sodium polyglutamate, sodium stearoyl glutamate, β-glucan, fructose, carbohydrate hydrolyzate, carbomer, collagen, hydrolyzed collagen, and glycoprotein; The emollient includes one or more combinations of caprylic / capric triglyceride, glyceryl stearate, polyglyceryl-10 oleate, polysorbate-20, glyceryl caprylate, hydrogenated lecithin, and phosphatidylcholine; The antioxidant includes one or more combinations of hydroxypropyl tetrahydropyrantriol, p-hydroxyacetophenone, and tocopheryl acetate; The skin conditioning agent includes a combination of one or more of cynanchum atratum extract, licorice root extract, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, decapeptide-4, ceramide NP, and bisabolol.

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