Incubation reaction device and in-vitro diagnostic analysis system

Abstract

The invention relates to an incubation reaction device and an in-vitro diagnostic analysis system. A first carrying assembly carries a reaction container to a supporting part located at a first station; the rotating frame drives the supporting part to move from the first station to the second station so as to inject the reagent into the reaction container; the rotating frame drives the supporting part to move from the second station to the third station so as to inject the sample into the reaction container; the rotating frame drives the supporting part to move from the third station to the fourth station for uniform mixing treatment; and the rotating frame drives the supporting part to move to the first station to carry the reaction container subjected to uniform mixing treatment to the incubation disc for incubation treatment. Therefore, in the process of completing reagent adding, sample adding and uniform mixing, the reaction container does not need to be grabbed and transferred, so that the task of carrying components is reduced, the number of using device parts is reduced, and the cost is reduced; meanwhile, the actions required by all the parts are reduced, the available time for completing each action is prolonged, and therefore the requirement for the performance of the parts is lowered.

Description

Technical Field

[0001] The present application relates to the field of in vitro diagnostic analysis technology, and in particular to an incubation reaction device and an in vitro diagnostic analysis system. Background Art

[0002] In vitro diagnostic analysis systems, including but not limited to chemiluminescent immunoassays, are immunoassay methods that use chemiluminescent agents to directly label antigens or antibodies. Over the past decade, chemiluminescent immunoassay technology has rapidly developed worldwide. Although chemiluminescent immunoassay technology has matured, the number of fully automatic devices that support this technology is still growing. Test throughput, which determines the number of tests an instrument can perform per unit time, has always been an important indicator that instrument manufacturers have attempted to improve. In related technologies, improving test throughput involves using more components to complete tasks faster, which in turn increases instrument costs. Summary of the Invention

[0003] Based on this, it is necessary to overcome the defects of the existing technology and provide an incubation reaction device and in vitro diagnostic analysis system, which can reduce the number of components used and achieve cost reduction while ensuring high test throughput; at the same time, it can reduce the actions required for each component, thereby increasing the time available to complete each action, thereby reducing the requirements for the performance of the components.

[0004] An incubation reaction device, comprising:

[0005] an incubation tray, wherein the incubation tray is used to incubate the reaction container;

[0006] A turret, the turret comprising at least one support portion configured to support the reaction vessel; the turret being capable of rotating independently of the incubation tray to drive the support portion to rotate circumferentially around the incubation tray, and capable of rotating to at least four stations, the at least four stations comprising a first station, a second station, a third station, and a fourth station;

[0007] a first transport assembly capable of transporting the reaction container to the support portion located at the first station, removing the reaction container from the support portion located at the first station, and transporting the reaction container located at the first station to the incubation tray;

[0008] a reagent dispensing assembly capable of injecting a reagent into the reaction container located at the second station;

[0009] a sample dispensing component capable of injecting a sample into the reaction container located at the third station; and

[0010] The first mixing mechanism can mix the reaction container located at the fourth station.

[0011] In one embodiment, there are at least four support parts; the support parts are arranged at equal intervals, the central angle of any two adjacent support parts with respect to the center of the incubation plate is a first central angle, the central angle of any two adjacent workstations is a second central angle, and the second central angle is an integer multiple of the first central angle.

[0012] In one embodiment, each of the supporting portions includes at least two supporting units, and each of the supporting units is capable of supporting the reaction container.

[0013] In one embodiment, the supporting unit of each supporting portion is arranged radially along the incubation tray.

[0014] In one embodiment, the first station, the third station, the fourth station, and the second station are sequentially arranged along the circumference of the incubation tray.

[0015] In one embodiment, the incubation reaction device also includes a second transport component; the rotating frame can also rotate to the fifth station; the second transport component can transfer the reaction container outward from the fifth station, or transfer the reaction container of the incubation plate to the support part of the fifth station through the second transport component.

[0016] In one embodiment, when the support portion rotates to the first station, the first transport assembly can transport the reaction container on one of the support units on the support portion to another support unit or to the incubation tray.

[0017] In one embodiment, when the support portion rotates to the third position, the sample dispensing assembly can absorb the pretreated sample inside the reaction container on the support unit and transfer the pretreated sample to the reaction container on another support unit.

[0018] In one embodiment, two support units are provided and are arranged radially along the incubation tray. The support unit supporting the pre-treated sample reaction container is located close to the incubation tray, and the other support unit is located away from the incubation tray.

[0019] In one embodiment, the incubation reaction device further includes a first waste discharge component; when the support portion rotates to the fourth position, the first waste discharge component can discharge the pre-treated sample inside the reaction container on the support unit.

[0020] In one embodiment, two support units are provided and are radially arranged along the incubation tray, the reaction container on the support unit processed by the first waste discharge component is located close to the incubation tray, and the reaction container on the other support unit processed by the first mixing mechanism is located away from the incubation tray; and / or the waste discharge treatment and mixing treatment can be carried out simultaneously.

[0021] In one embodiment, the rotating frame is coaxially arranged with the incubation tray; the rotating frame includes a rotating ring arranged circumferentially around the incubation tray, and each of the supporting parts is arranged on the rotating ring.

[0022] In one embodiment, the incubation reaction device further includes a first driving mechanism and a second driving mechanism; the first driving mechanism is connected to the incubation tray and is used to drive the incubation tray to rotate; the second driving mechanism is connected to the rotating frame and is used to drive the rotating frame to rotate.

[0023] In one embodiment, the in vitro diagnostic analysis system comprises the incubation reaction device according to any one of claims 1 to 13.

[0024] In one embodiment, the in vitro diagnostic analysis system also includes: a reaction container loading device for providing reaction containers, a reagent management device for providing reagents, a magnetic separation and cleaning device for separation and cleaning, and a photometric waste discharge device for luminescence detection and waste discharge; the first conveying component can take the reaction container of the reaction container loading device and convey it to the support part located at the first station; the reagent dispensing component can absorb the reagent of the reagent management device and inject it into the reaction container located at the second station; the sample dispensing component can absorb the sample and inject it into the reaction container located at the third station; the first mixing mechanism can mix the reaction container located at the fourth station; the first conveying component can convey the mixed reaction container to the incubation plate.

[0025] In one embodiment, the in vitro diagnostic analysis system also includes: a reaction vessel loading device for providing reaction vessels, a reagent management device for providing reagents, a magnetic separation and cleaning device for separation and cleaning, and a photometric waste discharge device for luminescence detection and waste discharge; the first transport component can take the reaction vessel of the reaction vessel loading device and transport it to the support part located at the first station; the reagent dispensing component can absorb the reagent of the reagent management device and inject it into the reaction vessel located at the second station; the sample dispensing component can absorb the pretreated sample in the reaction vessel, the reaction vessel is located at the third station, and is located on a support unit close to the incubation disk; the sample dispensing component can transfer the pretreated sample to another reaction container at the third station, and the other reaction container is located on another support unit radially away from the incubation disk.

[0026] In one embodiment, the in vitro diagnostic analysis system also includes: a reaction container loading device for providing reaction containers, a reagent management device for providing reagents, a magnetic separation and cleaning device for separation and cleaning, and a photometric waste discharge device for luminescence detection and waste discharge; when the first transport component takes the reaction container of the reaction container loading device and transports it to the support part located at the first station, the reagent dispensing component can simultaneously absorb the reagent of the reagent management device and inject it into the reaction container located at the second station, the sample dispensing component can simultaneously absorb the sample and inject it into the reaction container located at the third station, and the first mixing mechanism can simultaneously mix the reaction container located at the fourth station.

[0027] In one embodiment, the in vitro diagnostic analysis system further includes a second transport component, which can transfer the reaction container between the rotating rack, the incubation plate, the magnetic separation and cleaning device, and the photometric waste discharge device.

[0028] In one embodiment, the in vitro diagnostic analysis system also includes a work platform; the incubation reaction device, the reaction container loading device, the reagent management device, the magnetic separation and cleaning device, and the photometric waste discharge device are all arranged on the work platform; the in vitro diagnostic analysis system also includes a controller; the controller is respectively connected to the first transport component, the reagent dispensing component, the sample dispensing component, the first mixing mechanism, the reaction container loading device, the reagent management device, the magnetic separation and cleaning device, the photometric waste discharge device and the second transport component.

[0029] The above-mentioned incubation reaction device and in vitro diagnostic analysis system, when working, the first transport component transports the reaction container to the support part located at the first station, completing the loading action of the reaction container; the rotating frame drives the support part to move from the first station to the second station, and the reagent dispensing component injects the reagent into the reaction container; the rotating frame drives the support part to move from the second station to the third station, and the sample dispensing component injects the sample into the reaction container; the rotating frame drives the support part to move from the third station to the fourth station, and the first mixing mechanism can mix the reagent and sample in the reaction container; the rotating frame drives the support part to move to the first station, and the first transport component can transport the mixed reaction container to the incubation tray, and incubate the reaction container through the incubation tray. It can be seen that by setting a rotating rack on the periphery of the incubation plate, the reaction container does not need to be grabbed and transferred during the process of adding reagents, adding samples, and mixing, which reduces the task of transporting components. Therefore, on the basis of ensuring high test throughput, the number of components used can be reduced, thereby reducing costs; at the same time, the actions required for each component are reduced, and the time available to complete each action is increased, thereby reducing the requirements for the performance of the components. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 FIG. 1 is a structural diagram of an in vitro diagnostic analysis system according to an embodiment of the present application.

[0031] Figure 2 for Figure 1 A one-way structural diagram of the incubation reaction device in the structure shown.

[0032] Figure 3 for Figure 1 Another perspective structural diagram of the incubation reaction device in the structure shown.

[0033] Figure 4 for Figure 1 Another perspective structural diagram of the incubation reaction device in the structure shown.

[0034] 10. Incubation reaction device; 11. Incubation plate; 12. Rotating rack; 121. Support part; 1211. Support unit; 122. Rotating ring; 13. First transport component; 14. Reagent dispensing component; 15. Sample dispensing component; 16. First mixing mechanism; 17. First waste discharge component; 18. First driving mechanism; 19. Second driving mechanism; A. First station; B. Second station; C. Third station; D. Fourth station; E. Fifth station; 30. Reaction vessel loading device; 40. Reagent management device; 50. Magnetic separation and cleaning device; 60. Photometric waste discharge device; 70. Second transport component; 80. Work platform. DETAILED DESCRIPTION

[0035] To make the above-mentioned objects, features, and advantages of the present application more clearly understood, the specific embodiments of the present application are described in detail below with reference to the accompanying drawings. The following description sets forth many specific details to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways than those described herein, and those skilled in the art can make similar improvements without violating the scope of the present application. Therefore, the present application is not limited to the specific embodiments disclosed below.

[0036] As described in the background art, there has always been a contradiction in the fully automatic chemiluminescence immunoassay analyzer in the related art: on the one hand, it is hoped to increase the test throughput of the instrument to provide higher detection efficiency, so it is necessary to increase the number of components to reduce the tasks of a single component (to achieve an increase in the execution speed of the component), thereby increasing the cost; on the other hand, it is hoped that the instrument design will be simpler and the number of components will be reduced to reduce costs and control the failure rate.

[0037] Based on the above reasons, the present application provides an incubation reaction device and an in vitro diagnostic analysis system, which reduces the number of components used and reduces costs while ensuring high test throughput; at the same time, it reduces the actions required for each component, thereby increasing the time available to complete each action, thereby reducing the requirements for the performance of the components.

[0038] See Figures 1 to 4 , Figure 1 FIG1 shows a structural diagram of an in vitro diagnostic analysis system according to an embodiment of the present application. Figures 2 to 4 Shown respectively Figure 1Three different perspective structural diagrams of the incubation reaction device 10 in the structure shown. An incubation reaction device 10 provided in one embodiment of the present application includes: an incubation tray 11, a rotating rack 12, a first transport assembly 13, a reagent dispensing assembly 14, a sample dispensing assembly 15 and a first mixing mechanism 16. The incubation tray 11 is used to incubate the reaction vessel. The rotating rack 12 includes at least one support portion 121, and the support portion 121 is used to support the reaction vessel. The rotating rack 12 can rotate independently of the incubation tray 11 to drive the support portion 121 to rotate circumferentially around the incubation tray 11, and can rotate to at least four stations. The at least four stations include a first station A, a second station B, a third station C and a fourth station D. Specifically, the first station A, the third station C, the fourth station D and the second station B are arranged in sequence along the circumference of the incubation tray 11. The first transport assembly 13 can transport the reaction container to the support portion 121 located at the first station A, remove the reaction container from the support portion 121 located at the first station A, and transport the reaction container to the incubation tray 11. The reagent dispensing assembly 14 can inject reagents into the reaction container located at the second station B. The sample dispensing assembly 15 can inject samples into or extract samples from the reaction container located at the third station C. The first mixing mechanism 16 can mix the reaction container located at the fourth station D.

[0039] When the above-mentioned incubation reaction device 10 is working, the first conveying component 13 conveys the reaction container to the support part 121 located at the first station A to complete the loading action of the reaction container; the rotating frame 12 drives the support part 121 to move from the first station A to the second station B, and the reagent dispensing component 14 injects the reagent into the reaction container; the rotating frame 12 drives the support part 121 to move from the second station B to the third station C, and the sample dispensing component 15 injects the sample into the reaction container; the rotating frame 12 drives the support part 121 to move from the third station C to the fourth station D, and the first mixing mechanism 16 can mix the reagent and sample in the reaction container; the rotating frame 12 drives the support part 121 to move to the first station A, and the first conveying component 13 can convey the mixed reaction container to the incubation tray 11, and incubate the reaction container through the incubation tray 11. It can be seen that by arranging a rotating rack 12 on the periphery of the incubation plate 11, the reaction container does not need to be grabbed and transferred during the process of adding reagents, adding samples, and mixing, thereby reducing the task of transporting components. Therefore, on the basis of ensuring high test throughput, the number of used components can be reduced, thereby reducing costs; at the same time, the actions required for each component are reduced, and the time available to complete each action is increased, thereby reducing the requirements for the performance of the component.

[0040] In some embodiments, the number of support portions 121 is not limited to one, but may be multiple, such as two, three, four, or more. The number of support portions 121 may be greater than, less than, or equal to the number of workstations. During the rotation of the turret 12 to adjust its position, at least two support portions 121 correspond to at least two workstation positions, thereby enabling simultaneous execution of at least two process steps and improving testing throughput.

[0041] In one embodiment, there are at least four support portions 121. The support portions 121 are arranged at equal intervals, and the central angle between any two adjacent support portions 121 and the center of the incubation tray 11 is a first central angle, and the central angle between any two adjacent workstations is a second central angle, which is an integer multiple of the first central angle.

[0042] Specifically, the number of support sections 121 is the same as the number of workstations, and each support section 121 corresponds to a corresponding workstation position. This allows each support section 121 to be positioned at a different workstation during rotation of the turret 12. Thus, while one support section 121 is removing a reaction vessel at workstation A, another support section 121 is injecting reagents at workstation B, another support section 121 is injecting samples at workstation C, and yet another support section 121 is performing mixing at workstation D. This allows simultaneous removal of reaction vessels, addition of reagents, addition of samples, and mixing, thereby achieving higher test throughput at the same execution speed.

[0043] The number of workstations is not limited to four, but may be five, six, seven, eight or more.

[0044] See also Figures 1 to 4 In a specific embodiment, the workstations are set to five, for example, of which four are respectively the first workstation A, the second workstation B, the third workstation C and the fourth workstation D, and the other workstation is the fifth workstation E. The workstations are arranged at equal intervals, and the central angle between two adjacent workstations with respect to the center of the incubation tray 11 is 72°. In addition, the number of support portions 121 is correspondingly set to five, and the central angle between two adjacent support portions 121 with respect to the center of the incubation tray 11 is 72°. The specific functions of the fifth workstation E can be flexibly adjusted and set according to actual needs, such as the transfer function. Specifically, the reaction container is transferred outward from the fifth workstation E by the second conveying component 70, or the reaction container of the incubation tray 11 is transferred to the support portion 121 of the fifth workstation E by the second conveying component 70.

[0045] The pretreatment process in the related art adds a reaction vessel and a processing process compared to the conventional process, which often leads to the contradiction of either adding additional devices, slowing down the devices, or improving the performance of the devices. Based on this, in this embodiment, please refer to Figures 1 to 4 , each support portion 121 includes at least two support units 1211. Each support unit 1211 can support a reaction container. Specifically, when the support portion 121 rotates to the first station A, the first transport component 13 can transport the reaction container on one of the support units 1211 on the support portion 121 to another support unit 1211 or to the incubation tray 11; when the support portion 121 rotates to the third station C, the sample dispensing component 15 can inject the sample into the reaction container on the first support unit 1211, can absorb the pretreated sample inside the reaction container on the support unit 1211, and transfer the pretreated sample to the reaction container on another support unit 1211. The pretreatment in this embodiment includes but is not limited to pre-dilution treatment, etc., which is not limited here. In this way, on the basis of the conventional process of the incubation reaction device 10, the pretreatment process can also be implemented to further improve the product performance of the device. In addition, in the pre-processing process, there is no need to add additional components. For example, it can be supported by the outer ring support unit 1211 on the transfer rack. There is no need to bring additional requirements to the performance of the components, and the increase in device costs is avoided. At the same time, the work efficiency is high.

[0046] There are two supporting units 1211 and they are arranged radially along the incubation tray 11 . The supporting unit 1211 supporting the pre-treated sample reaction container is located close to the incubation tray 11 , and the other supporting unit 1211 is located away from the incubation tray 11 .

[0047] See also Figures 1 to 4 In one embodiment, the incubation reaction device 10 further includes a first waste discharge assembly 17. When the support portion 121 rotates to, for example, the fourth station D or another station, the first waste discharge assembly 17 can discharge the pretreated sample from the reaction vessel on the other support unit 1211. This allows the incubation reaction device 10 to also function as a waste discharge, eliminating the need for handling and transfer, reducing the burden on handling components. This reduces the number of instrument components used while maintaining high test throughput, thereby lowering costs. Furthermore, the number of actions required by each instrument component is reduced, increasing the time available to complete each action and thus lowering the performance requirements of the instrument components. Furthermore, simultaneous removal of reaction vessels, addition of reagents, addition of samples, mixing, and waste discharge can be achieved, thereby achieving higher test throughput at the same execution speed. Specifically, two support units 121 are provided and arranged radially along the incubation tray 1211. The reaction vessels on the support unit 121 handled by the first waste discharge assembly 17 are located closer to the incubation tray 1211, while the reaction vessels on the other support unit 121 handled by the first mixing mechanism 16 are located further away from the incubation tray 1211. In addition, the waste discharge treatment and the mixing treatment can be performed simultaneously or independently, which is not limited here.

[0048] In some embodiments, for each support portion 121, when the support portion 121 rotates to the first station A, the first transport component 13 can access each support unit 1211 of the support portion 121 respectively, that is, it can realize transporting the reaction container to each support unit 1211, and can also take away and transport the reaction container of each support unit 1211 to the incubation tray 11, and can realize the transfer position of the reaction container between each support unit 1211; when the support portion 121 rotates to the second station B, the reagent dispensing component 14 can access each support unit 1211 of the support portion 121 respectively, that is, it can inject the reagent into the reaction of any support unit 1211 according to actual needs. when the support portion 121 rotates to the third station C, the sample dispensing component 15 can access each support unit 1211 of the support portion 121 respectively, that is, it can inject the sample into the reaction container of any support unit 1211 or absorb the pretreated sample from the reaction container of the support unit 1211 according to actual needs; when the support portion 121 rotates to the fourth station D, the first mixing mechanism 16 can access one of the support units 1211 to mix the reaction container located in one of the support units 1211, and the first waste discharge component 17 can access another support unit 1211 to discharge the reaction container located in the other support unit 1211.

[0049] In order to facilitate each support unit 1211 of support portion 121 to be accessed by first transport assembly 13, reagent dispensing assembly 14, sample dispensing assembly 15, first waste discharge assembly 17 respectively, first transport assembly 13, sample dispensing assembly 15, first waste discharge assembly 17, reagent dispensing assembly 14 are arranged circumferentially along the incubation tray rotation path. Optionally, first transport assembly 13, reagent dispensing assembly 14, sample dispensing assembly 15 are arranged independently of each other, for example, all include swing arm mechanism, i.e. horizontal rotation adjustment position, motion path is an arc line, also include the lifting mechanism connected with the swing arm mechanism, by lifting motion close to or away from reaction vessel. In addition, first transport assembly 13 also includes the gripper connected with lifting mechanism, gripper can be to adopt various structural forms, as long as can realize grabbing or unclamping reaction vessel. Reagent dispensing assembly 14 also includes the reagent needle connected with lifting mechanism, and reagent needle moves to reaction vessel inside and fills reagent under the effect of lifting mechanism and swing arm mechanism. The sample dispensing assembly 15 further includes a sample needle connected to the lifting mechanism. The sample needle moves into the reaction container under the action of the lifting mechanism and the swing arm mechanism to add the sample.

[0050] Optionally, the support units 1211 of the support portion 121 are arranged along the radial direction of the incubation tray 11. When each support portion 121 has two support units 1211, the support units 1211 of each support portion 121 close to the center of the incubation tray 11 are combined to form an inner ring, and the support units 1211 of each support portion 121 away from the center of the incubation tray 11 are combined to form an outer ring. When the outer ring is used for the pre-processing process, the inner ring is used for the further processing process; when the inner ring is used for the pre-processing process, the outer ring is used for the further processing process.

[0051] As some optional solutions, the first transport component 13, the reagent dispensing component 14, and the sample dispensing component 15 are not limited to including a swing arm mechanism, but can also include a moving mechanism that moves along the X-axis and / or Y-axis, so as to achieve flexible position adjustment along the X-axis and / or Y-axis.

[0052] See also Figures 1 to 4 In one embodiment, the rotating frame 12 is coaxially arranged with the incubation tray 11. The rotating frame 12 includes a rotating ring 122 arranged circumferentially around the incubation tray 11, and each support portion 121 is disposed on the rotating ring 122. Optionally, the support unit 1211 includes but is not limited to a fixing seat, a positioning recess, a socket, etc., as long as it can position and support the reaction container.

[0053] See also Figure 1 and Figure 3 In one embodiment, the incubation reaction device 10 further includes a first driving mechanism 18 and a second driving mechanism 19. The first driving mechanism 18 is connected to the incubation tray 11 for driving the incubation tray 11 to rotate; the second driving mechanism 19 is connected to the rotating frame 12 for driving the rotating frame 12 to rotate.

[0054] Optionally, the first drive mechanism 18 and the second drive mechanism 19 are independently configured according to actual needs, as long as they are sufficient to drive the respective connected disks to rotate, including but not limited to motors, or other power mechanisms.

[0055] In one embodiment, the first mixing mechanism 16 includes but is not limited to at least one of an eccentric rotation mechanism, a concentric rotation mechanism, an ultrasonic mixing mechanism, a vibration mixing mechanism, and a repeated suction and discharge mixing mechanism.

[0056] In this embodiment, the first mixing mechanism 16 is specifically configured as an eccentric rotating mechanism, and the eccentric rotating mechanism is arranged below the support portion 121. The first mixing mechanism 16 also includes a lifting mechanism connected to the eccentric rotating mechanism. The lifting mechanism can lift the eccentric rotating mechanism so that the eccentric rotating part of the eccentric rotating mechanism supports the reaction container and drives the reaction container to rotate, thereby realizing the mixing action of the sample and reagent inside the reaction container.

[0057] In one embodiment, the first waste discharge assembly 17 includes a lifting mechanism and a suction needle connected to the lifting mechanism. The lifting mechanism drives the suction needle to extend into the interior of the reaction vessel located at the fourth station D, where the suction needle is used to aspirate waste liquid from the reaction vessel. Thus, when the reaction vessel is moved to the fourth station D, the lifting mechanism drives the suction needle into the reaction vessel, where it aspirates and discharges the waste liquid from the reaction vessel. After the waste liquid from the reaction vessel is discharged, the lifting mechanism drives the suction needle upward, removes it from the reaction vessel, and prepares to drain the next reaction vessel.

[0058] In some embodiments, the incubation reaction device 10 further includes a heating mechanism for heating the incubation tray 11 to a preset temperature according to actual needs, thereby incubating the reaction container.

[0059] See also Figures 1 to 4 In one embodiment, an in vitro diagnostic analysis system includes the incubation reaction device 10 of any of the above embodiments.

[0060] When the above-mentioned in vitro diagnostic analysis system is working, the first transport component 13 transports the reaction container to the support part 121 located at the first station A to complete the loading action of the reaction container; the rotating frame 12 drives the support part 121 to move from the first station A to the second station B, and the reagent dispensing component 14 injects the reagent into the reaction container; the rotating frame 12 drives the support part 121 to move from the second station B to the third station C, and the sample dispensing component 15 injects the sample into the reaction container; the rotating frame 12 drives the support part 121 to move from the third station C to the fourth station D, and the first mixing mechanism 16 can mix the reagent and sample in the reaction container; the rotating frame 12 drives the support part 121 to move to the first station A, and the first transport component 13 can transport the mixed reaction container to the incubation tray 11, and incubate the reaction container through the incubation tray 11. It can be seen that by arranging a rotating rack 12 on the periphery of the incubation plate 11, the reaction container does not need to be grabbed and transferred during the process of adding reagents, adding samples, and mixing, thereby reducing the task of transporting components. Therefore, on the basis of ensuring high test throughput, the number of used components can be reduced, thereby reducing costs; at the same time, the actions required for each component are reduced, and the time available to complete each action is increased, thereby reducing the requirements for the performance of the component.

[0061] See also Figures 1 to 4In one embodiment, the in vitro diagnostic analysis system further includes: a reaction vessel loading device 30 for providing reaction vessels, a reagent management device 40 for providing reagents, a magnetic separation and cleaning device 50 for separation and cleaning, a photometric waste discharge device 60 for luminescence detection and waste discharge, and a second transport component 70. The first transport component 13 can take the reaction vessel of the reaction vessel loading device 30 and transport it to the support portion 121 located at the first station A; the reagent dispensing component 14 can absorb the reagent from the reagent management device 40 and inject it into the reaction vessel located at the second station B; the sample dispensing component 14 can absorb the sample and inject it into the reaction vessel located at the third station C; the first mixing mechanism 16 can mix the reaction vessel located at the fourth station D; and the first transport component 13 can transport the mixed reaction vessel to the incubation tray 11.

[0062] In addition, the second transport assembly 70 can be used to transfer the reaction container between the incubation tray 11, the magnetic separation and cleaning device 50, and the photometric waste discharge device 60. Specifically, the second transport assembly 70 can also be used to transfer the reaction container between the incubation tray 11, the fifth station E of the rotating rack 12, the magnetic separation and cleaning device 50, the photometric waste discharge device 60, and the cup throwing position.

[0063] The in vitro diagnostic analysis system further includes a fluidic device. The fluidic device is connected to the sample dispensing assembly 15, the reagent dispensing assembly 14, and the magnetic separation and cleaning assembly. The fluidic device controls the sample dispensing assembly 15 to aspirate and discharge samples and clean the sample dispensing assembly 15, controls the reagent dispensing assembly 14 to aspirate and discharge reagents and clean the reagent dispensing assembly 14, and is also used to inject or discharge cleaning fluid into or out of the magnetic separation and cleaning assembly 50.

[0064] Optionally, the specific structural composition of the second transport assembly 70 can be the same as or different from the specific structural composition of the first transport assembly 13, as long as the reaction container can be transferred, and is not limited here.

[0065] In some embodiments, the in vitro diagnostic analysis system further includes: a reaction vessel loading device 30 for providing reaction vessels, a reagent management device 40 for providing reagents, a magnetic separation and cleaning device 50 for separation and cleaning, and a photometric waste discharge device 60 for luminescence detection and waste discharge. The first transport component 13 can take the reaction vessel of the reaction vessel loading device 30 and transport it to the support portion 121 located at the first station A; the reagent dispensing component can absorb the reagent from the reagent management device 40 and inject it into the reaction vessel located at the second station B; the sample dispensing component 15 can absorb the pretreated sample from the reaction vessel, which is located at the third station C and is located on a support unit 1211 close to the incubation tray 11; the sample dispensing component 15 can transfer the pretreated sample to another reaction vessel at the third station C, which is located on another support unit 1211 radially away from the incubation tray 11.

[0066] In some embodiments, the in vitro diagnostic analysis system also includes: a reaction vessel loading device 30 for providing reaction vessels, a reagent management device 40 for providing reagents, a magnetic separation and cleaning device 50 for separation and cleaning, and a photometric waste discharge device 60 for luminescence detection and waste discharge; when the first transport component 13 takes the reaction vessel of the reaction vessel loading device 30 and transports it to the support part 121 located at the first station A, the reagent dispensing component 14 can simultaneously absorb the reagent from the reagent management device 40 and inject it into the reaction vessel located at the second station B, the sample dispensing component 15 can simultaneously absorb the sample and inject it into the reaction vessel located at the third station C, and the first mixing mechanism 16 can simultaneously mix the reaction vessel located at the fourth station D.

[0067] In some embodiments, in one embodiment, the in vitro diagnostic analysis system further comprises a substrate filling device and a second mixing mechanism. The substrate filling device and the second mixing mechanism are both connected to the magnetic separation cleaning device 50, and the substrate filling device is used to fill the reaction vessel after the magnetic separation cleaning with luminescent substrate, and the second mixing mechanism is used to mix the reaction vessel filled with the luminescent substrate. In this way, in order to increase the luminescence value during the detection of the analyte, the luminescent substrate is added to the reaction vessel after the separation and cleaning, and the luminescent substrate adheres to the analyte, which can increase the luminescence value of the analyte and ensure the accuracy of the sample detection. Specifically, after the reaction vessel completes the magnetic separation and cleaning operation in the magnetic separation cleaning device 50, the luminescent substrate is filled into the reaction vessel by the substrate filling device, and the reaction vessel filled with the luminescent substrate is mixed by the second mixing mechanism. In this way, there is no need to transfer the reaction vessel after the magnetic separation and cleaning to other locations for the addition and mixing of the luminescent substrate as required in the related art, that is, the transfer step of the reaction vessel is omitted, thereby further improving the test throughput.

[0068] See also Figure 1 and Figure 4 In some embodiments, the substrate filling device is connected to the liquid circuit device, and the liquid circuit device can also provide power to control the substrate filling device to fill the luminescent substrate into the interior of the reaction vessel, and can control the filling amount of the luminescent substrate. Optionally, the substrate filling device includes a lifting mechanism and a substrate filling needle. The lifting mechanism is connected to the substrate filling needle. When the reaction vessel after magnetic separation and cleaning is moved to the substrate filling station, the lifting mechanism drives the substrate filling needle to move up and down, so that the substrate filling needle enters the interior of the reaction vessel and fills the luminescent substrate into the interior of the reaction vessel. After the luminescent substrate is filled, on the one hand, the reaction vessel filled with the luminescent substrate is mixed by the second mixing mechanism, and on the other hand, the lifting mechanism synchronously drives the substrate filling needle to move in the opposite direction, so that the substrate filling needle leaves the reaction vessel to prepare for the substrate filling operation of the next reaction vessel.

[0069] In some embodiments, the magnetic separation cleaning device 50 is provided with multiple rotatable placement parts, which are used to support reaction containers. The second mixing mechanism is respectively connected to each placement part, and is used to drive each placement part to rotate, thereby driving the reaction containers on each placement part to rotate, thereby realizing non-contact mixing processing of each reaction container.

[0070] Of course, the second mixing mechanism can also use other methods to achieve the mixing operation of the luminescent substrate inside the reaction vessel, for example, by inserting a needle to repeatedly suck and spit out the liquid inside the reaction vessel to achieve mixing; for example, a magnet is placed inside the reaction vessel, and the magnetic force acts on the magnetic beads to drive the magnetic beads to move back and forth inside the reaction vessel, thereby achieving the mixing operation of the luminescent substrate inside the reaction vessel; for example, ultrasonic mixing is used to achieve mixing of the liquid inside the reaction vessel.

[0071] In some embodiments, the magnetic separation cleaning device 50 only needs to be satisfied with cleaning the test object and impurities in the reaction container to remove the impurities in the reaction container so that only the test object exists in the reaction container. Various types of magnetic separation cleaning devices 50 in the relevant technology can be used, and no specific limitations are given here. In this embodiment, the magnetic separation cleaning device 50 includes a magnetic separation disk and a lifting mechanism. Among them, the magnetic separation disk includes a first tray rotating around the axis, an outer shell and a magnet array. An opening is provided on the top surface of the outer shell for the second transport component 70 to take and place the reaction container. After the reaction container is placed on the first tray, it is driven by the first tray to transfer between the various magnetic separation cleaning stations, and then taken out after cleaning is completed. During the transfer process, the lifting mechanism can extend the cleaning waste discharge needle into the reaction container, and realize the injection and discharge of the cleaning liquid under the drive of the liquid path device. Specifically, a substrate injection position is also provided on the outer shell, and the luminescent substrate can be injected into the cleaned reaction container in the magnetic separation cleaning device 50. The second mixing mechanism is arranged below the magnetic separation disk, which can perform non-contact mixing on the reaction container injected with the luminescent substrate.

[0072] In some embodiments, the photometric waste removal device 60 comprises a rotatable photometric disc, a fixed photometric element, and a second waste removal assembly. The photometric disc is provided with at least three testing sections, each for placing a reaction vessel. When a reaction vessel in one testing section rotates to a position corresponding to the photometric element, a reaction vessel in another testing section rotates to a position corresponding to the second waste removal assembly, and one testing section rotates to a loading and unloading position. This allows simultaneous photometric processing, waste removal, and loading and unloading of the reaction vessels, thereby increasing testing throughput.

[0073] In some embodiments, the reaction vessel loading device 30 includes a hopper for placing reaction vessels, a slide, and a cup supply carousel. The hopper is connected to the cup supply carousel via the slide. A lifting device within the hopper pushes the reaction vessel onto the slide. The reaction vessel falls through the slide into an empty cup position on the cup supply carousel, which then rotates the cup supply carousel to a position where it can be grasped by the first transport assembly 13.

[0074] In some embodiments, the in vitro diagnostic analysis system further includes a controller. The controller is connected to the first transport assembly 13, the reagent dispensing assembly 14, the sample dispensing assembly 15, the first mixing mechanism 16, the reaction vessel loading device 30, the reagent management device 40, the magnetic separation and cleaning device 50, the photometric waste discharge device 60, and the second transport assembly 70, respectively, and coordinates their operation under the control of the controller.

[0075] In some embodiments, in order to more accurately control the operation of the first transport component 13, the second transport component 70, the reagent dispensing component 14, the sample dispensing component 15, and the first mixing mechanism 16, the in vitro diagnostic analysis system also includes at least one position sensor, which is electrically connected to the controller. The position sensor senses the movement position of the support part 121 of the rotating frame 12 and sends the position signal of the support part 121 to the controller, and operates under the control of the controller.

[0076] See also Figures 1 to 4 In one embodiment, the in vitro diagnostic analysis system further includes a work platform 80. The incubation reaction device 10, the reaction vessel loading device 30, the reagent management device 40, the magnetic separation and cleaning device 50, the photometric waste discharge device 60, and the second transport assembly 70 are all disposed on the work platform 80.

[0077] See also Figures 1 to 4 In a specific embodiment, for example, when the sample concentration is too high and the sample needs to be diluted, that is, when the sample needs to be pre-treated, the workflow of the in vitro diagnostic analysis system for the same sample includes the following steps:

[0078] Step S100, the initial step, includes: the first transport component 13 transports the reaction container to the support unit 1211 located on the outer ring of the first station A, completing the loading action of the reaction container; the rotating frame 12 drives the support part 121 to move from the first station A to the second station B, and the reagent dispensing component 14 injects the reagent into the reaction container; the rotating frame 12 drives the support part 121 to move from the second station B to the third station C, and the sample dispensing component 15 injects the sample into the reaction container; the rotating frame 12 drives the support part 121 to move from the third station C to the fourth station D, and the first mixing mechanism 16 can mix the reagent and sample in the reaction container to achieve pre-dilution treatment of the sample in the reaction container; the rotating frame 12 drives the support part 121 to move to the first station A.

[0079] Step S200: At the first workstation A, the first transport assembly 13 transports the pre-dilution reaction vessel to the inner ring support unit 1211; the first transport assembly 13 transports a new reaction vessel from the reaction vessel loading device 30 to the outer ring support unit 1211 on the support portion 121;

[0080] The rotating frame 12 drives the support part 121 to move from the first station A to the second station B, and the reagent dispensing component 14 injects the reagent into the reaction container in the outer circle; the rotating frame 12 drives the support part 121 to move from the second station B to the third station C, and the sample dispensing component 15 absorbs the sample inside the inner circle reaction container and injects it into the reaction container in the outer circle, that is, the pre-diluted sample completed in step S100 is absorbed into the new reaction container; the rotating frame 12 drives the support part 121 to move from the third station C to the fourth station D, the first mixing mechanism 16 mixes the reagent and sample in the outer circle reaction container, and the first waste discharge component 17 discharges the pre-diluted sample in the inner circle reaction container; the rotating frame 12 drives the support part 121 to move to the first station A.

[0081] Step S300, for the first workstation A, the first transport component 13 transports the reaction container on the outer ring support unit 1211 on the support part 121 to the incubation tray 11, thereby incubating the mixed reaction container in the incubation tray 11; the first transport component 13 transports another new reaction container from the reaction container loading device 30 to the outer ring support unit 1211 on the support part 121, and then starts a new round of adding reagents, adding samples and mixing; the first transport component 13 transports the reaction container on the inner ring support unit 1211 to the first throwing cup position (not shown in the figure).

[0082] It should be noted that, to make the above method easier to understand, steps S100 to S300 mainly describe the processing flow of the reaction vessels with reference to one of the support portions 121 on the incubation tray 11. Since there is more than one support portion 121 on the incubation tray 11, when one support portion 121 drives the reaction vessel to perform various processing operations, the remaining support portions 121 can simultaneously drive other reaction vessels to perform various processing operations, thereby greatly improving the test throughput.

[0083] In step S400, the second transport assembly 70 can transfer the reaction container after treatment on the incubation tray 11 to the magnetic separation and cleaning device 50. After cleaning by the magnetic separation and cleaning device 50, the luminescent substrate is added to the reaction container and mixed. The second transport assembly 70 can also transfer the reaction container from the magnetic separation and cleaning device 50 to the photometric waste discharge device 60, perform photometric treatment on the reaction container through the photometric waste discharge device 60, and discharge the waste liquid inside the reaction container after photometric treatment. The second transport assembly 70 transports the discharged reaction container to the second cupping position (not shown in the figure), completing the detection process of one sample.

[0084] Of course, in the above steps S100 and S200, step S100 can be replaced by the step of pre-treating the reaction vessel using an incubation tray. Accordingly, in step S200, for the first station A, the first transport assembly 13 transports the reaction vessel treated by the incubation tray to the inner ring support unit 1211, rather than transporting the pre-dilution treated reaction vessel to the inner ring support unit 1211. The remaining steps in S200, as well as steps S300 and S400, remain the same and are not further described here.

[0085] Through the above method, there is no need to add additional components to the structure. It can be achieved by reasonably setting the hole positions of the inner and outer rings of the transfer ring. There is no need to impose additional requirements on device performance and space, and at the same time, an increase in instrument costs is avoided.

[0086] Please continue reading Figures 1 to 4 In another specific embodiment, for example, for a sample that does not require pretreatment, the workflow method of the same sample in an in vitro diagnostic analysis system includes the following steps:

[0087] Step S100, the initial step, includes: the first transport component 13 transports the reaction container to the support unit 1211 located on the outer circle of the first station A to complete the loading action of the reaction container; the rotating frame 12 drives the support part 121 to move from the first station A to the second station B, and the reagent dispensing component 14 injects the reagent into the reaction container; the rotating frame 12 drives the support part 121 to move from the second station B to the third station C, and the sample dispensing component 15 injects the sample into the reaction container; the rotating frame 12 drives the support part 121 to move from the third station C to the fourth station D, and the first mixing mechanism 16 can mix the reagent and sample in the reaction container; the rotating frame 12 drives the support part 121 to move to the first station A.

[0088] Step S200 : For the first station A, the first transport assembly 13 transports the mixed reaction containers on the support unit 1211 located on the outer circle of the first station A to the incubation tray 11 .

[0089] In step S300, the second transport assembly 70 transfers the reaction container processed by the incubation tray 11 to the support unit 1211 on the outer ring of the fifth station E, the rotating frame 12 drives the support part 121 to move from the fifth station E to the second station B, and the reagent dispensing assembly 14 injects another reagent into the reaction container; the rotating frame 12 drives the support part 121 to move from the second station B to the fourth station D, and the first mixing mechanism 16 can mix the reagent and sample in the reaction container again; the rotating frame 12 drives the support part 121 to move to the first station A, and the first transport assembly 13 transports the mixed reaction container on the support unit 1211 on the outer ring of the first station A to the incubation tray 11.

[0090] It should be noted that step S300 can be performed according to specific detection needs, such as a two-step chemiluminescence method. For some detection samples, this step may not be included.

[0091] In step S400, the second transport assembly 70 transfers the reaction container after treatment on the incubation tray 11 to the magnetic separation and cleaning device 50. After cleaning by the magnetic separation and cleaning device 50, the luminescent substrate is added to the reaction container and mixed. The second transport assembly 70 can also transfer the reaction container from the magnetic separation and cleaning device 50 to the photometric waste discharge device 60, where the reaction container is photometrically treated and the waste liquid inside the reaction container after photometric treatment is discharged. The second transport assembly 70 transports the discharged reaction container to the second cupping position (not shown), completing the detection process for one sample.

[0092] In the description of this application, it should be understood that if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or position relationship indicated by these terms is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing this application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application.

[0093] In addition, if the terms "first" or "second" appear, these terms are used for descriptive purposes only and should not be understood to indicate or imply relative importance or implicitly specify the number of technical features indicated. Therefore, a feature specified as "first" or "second" may explicitly or implicitly include at least one of such features. In the description of this application, if the term "plurality" appears, "plurality" means at least two, for example, two, three, etc., unless otherwise specifically defined.

[0094] In this application, unless otherwise specified or limited, the terms "mounted," "connected," "connected," "fixed," etc., should be interpreted broadly. For example, these terms may refer to fixed connections, removable connections, or integration; mechanical connections or electrical connections; direct connections or indirect connections through an intermediary; and internal communication between two components or interaction between two components, unless otherwise specified. Those skilled in the art will understand the specific meanings of these terms in this application based on the specific circumstances.

[0095] In this application, unless otherwise expressly specified or limited, if a first feature is described as being "above" or "below" a second feature, or similar descriptions, this may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Furthermore, when a first feature is described as being "above," "above," or "above" a second feature, it may mean that the first feature is directly above or diagonally above the second feature, or simply means that the first feature is at a higher level than the second feature. When a first feature is described as being "below," "below," or "below" a second feature, it may mean that the first feature is directly below or diagonally below the second feature, or simply means that the first feature is at a lower level than the second feature.

[0096] It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be an intermediate element. If an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be an intermediate element. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this application are for illustrative purposes only and do not represent the only embodiment.

[0097] The technical features of the above-mentioned embodiments can be combined arbitrarily. In order to make the description concise, not all possible combinations of the technical features in the above-mentioned embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0098] The above-described embodiments merely represent several implementation methods of the present application. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that a person of ordinary skill in the art may make various modifications and improvements without departing from the spirit of the present application, and these modifications and improvements fall within the scope of protection of the present application. Therefore, the scope of protection of the present patent application shall be determined by the appended claims.

Claims

1. An incubation reaction device, characterized in that: The incubation reaction device comprises: an incubation tray, wherein the incubation tray is used to incubate the reaction container; A turret, the turret comprising at least one support portion configured to support the reaction vessel; the turret being capable of rotating independently of the incubation tray to drive the support portion to rotate circumferentially around the incubation tray, and capable of rotating to at least four stations, the at least four stations comprising a first station, a second station, a third station, and a fourth station; a first transport assembly capable of transporting the reaction container to the support portion located at the first station, removing the reaction container from the support portion located at the first station, and transporting the reaction container located at the first station to the incubation tray; a reagent dispensing assembly capable of injecting a reagent into the reaction container located at the second station; a sample dispensing component capable of injecting a sample into the reaction container located at the third station; and The first mixing mechanism can mix the reaction container located at the fourth station.

2. The incubation reaction device according to claim 1, characterized in that: There are at least four support parts; the support parts are arranged at equal intervals, the central angle of any two adjacent support parts relative to the center of the incubation plate is a first central angle, the central angle of any two adjacent workstations is a second central angle, and the second central angle is an integer multiple of the first central angle.

3. The incubation reaction device according to claim 1 or 2, characterized in that: Each of the supporting parts includes at least two supporting units, and each of the supporting units is capable of supporting the reaction container.

4. The incubation reaction device according to claim 3, characterized in that: The supporting units of each supporting portion are arranged radially along the incubation tray.

5. The incubation reaction device according to claim 3, characterized in that: The first workstation, the third workstation, the fourth workstation and the second workstation are sequentially arranged along the circumference of the incubation tray.

6. The incubation reaction device according to claim 3, characterized in that: The incubation reaction device also includes a second transport assembly; the rotating frame can also rotate to the fifth station; the second transport assembly can transfer the reaction container outward from the fifth station, or transfer the reaction container of the incubation tray to the support part of the fifth station through the second transport assembly.

7. The incubation reaction device according to claim 3, characterized in that: When the support portion rotates to the first station, the first transport assembly can transport the reaction container on one of the support units on the support portion to another support unit or to the incubation tray.

8. The incubation reaction device according to claim 3, characterized in that: When the support portion rotates to the third position, the sample dispensing assembly can absorb the pre-treated sample in the reaction container on the support unit and transfer the pre-treated sample to the reaction container on another support unit.

9. The incubation reaction device according to claim 8, characterized in that: There are two support units and they are arranged radially along the incubation tray. The support unit supporting the pre-treated sample reaction container is located close to the incubation tray, and the other support unit is located away from the incubation tray.

10. The incubation reaction device according to claim 3, characterized in that: The incubation reaction device further includes a first waste discharge component; when the support portion rotates to the fourth position, the first waste discharge component can discharge the pre-treated sample inside the reaction container on the support unit.

11. The incubation reaction device according to claim 10, characterized in that: There are two support units and they are arranged radially along the incubation tray. The reaction container on the support unit processed by the first waste discharge component is located close to the incubation tray, and the reaction container on the other support unit processed by the first mixing mechanism is located away from the incubation tray; and / or the waste discharge treatment and mixing treatment can be carried out simultaneously.

12. The incubation reaction device according to claim 3, characterized in that: The rotating frame is coaxially arranged with the incubation tray; the rotating frame comprises a rotating ring arranged circumferentially around the incubation tray, and each of the supporting parts is arranged on the rotating ring.

13. The incubation reaction device according to claim 3, characterized in that: The incubation reaction device further includes a first driving mechanism and a second driving mechanism; the first driving mechanism is connected to the incubation tray and is used to drive the incubation tray to rotate; the second driving mechanism is connected to the rotating frame and is used to drive the rotating frame to rotate.

14. An in vitro diagnostic analysis system, characterized in that: The in vitro diagnostic analysis system comprises the incubation reaction device according to any one of claims 1 to 13.

15. The in vitro diagnostic analysis system according to claim 14, characterized in that: The in vitro diagnostic analysis system also includes: a reaction container loading device for providing reaction containers, a reagent management device for providing reagents, a magnetic separation and cleaning device for separation and cleaning, and a photometric waste discharge device for luminescence detection and waste discharge; the first conveying component can take the reaction container of the reaction container loading device and convey it to the support part located at the first station; the reagent dispensing component can absorb the reagent of the reagent management device and inject it into the reaction container located at the second station; the sample dispensing component can absorb the sample and inject it into the reaction container located at the third station; the first mixing mechanism can mix the reaction container located at the fourth station; the first conveying component can convey the reaction container after mixing to the incubation plate.

16. The in vitro diagnostic analysis system according to claim 14, characterized in that: The in vitro diagnostic analysis system also includes: a reaction vessel loading device for providing reaction vessels, a reagent management device for providing reagents, a magnetic separation and cleaning device for separation and cleaning, and a photometric waste discharge device for luminescence detection and waste discharge; the first transport component can take the reaction vessel of the reaction vessel loading device and transport it to the support part located at the first station; the reagent dispensing component can absorb the reagent of the reagent management device and inject it into the reaction vessel located at the second station; the sample dispensing component can absorb the pretreated sample in the reaction vessel, the reaction vessel is located at the third station, and is located on a support unit close to the incubation tray; the sample dispensing component can transfer the pretreated sample to another reaction container at the third station, and the other reaction container is located on another support unit radially away from the incubation tray.

17. The in vitro diagnostic analysis system according to claim 14, characterized in that: The in vitro diagnostic analysis system also includes: a reaction container loading device for providing reaction containers, a reagent management device for providing reagents, a magnetic separation and cleaning device for separation and cleaning, and a photometric waste discharge device for luminescence detection and waste discharge; when the first transport component takes the reaction container of the reaction container loading device and transports it to the support part located at the first station, the reagent dispensing component can simultaneously absorb the reagent of the reagent management device and inject it into the reaction container located at the second station, the sample dispensing component can simultaneously absorb the sample and inject it into the reaction container located at the third station, and the first mixing mechanism can simultaneously mix the reaction container located at the fourth station.

18. The in vitro diagnostic analysis system according to any one of claims 15 to 17, characterized in that: The in vitro diagnostic analysis system further includes a second transport component, which can transfer the reaction container between the rotating rack, the incubation plate, the magnetic separation and cleaning device, and the photometric waste discharge device.

19. The in vitro diagnostic analysis system according to claim 15, characterized in that: The in vitro diagnostic analysis system also includes a work platform; the incubation reaction device, the reaction container loading device, the reagent management device, the magnetic separation and cleaning device, and the photometric waste discharge device are all arranged on the work platform; the in vitro diagnostic analysis system also includes a controller; the controller is respectively connected to the first transport component, the reagent dispensing component, the sample dispensing component, the first mixing mechanism, the reaction container loading device, the reagent management device, the magnetic separation and cleaning device, the photometric waste discharge device and the second transport component.

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