Cosmetic composition stabilized with water-dispersible organic-inorganic complex for ultraviolet

Abstract

The cosmetic composition according to the present invention is composed of an organic-inorganic composite, and thus can stabilize p-xylylene dichorsulfonic acid, titanium dioxide, aluminum hydroxide, and aminopropyltriethoxysilane in a dosage form, p-xylylene dichorsulfonic acid, titanium dioxide, aluminum hydroxide and aminopropyltriethoxysilane are ultraviolet-proof components capable of blocking ultraviolet rays in a wide wavelength range, so that an excellent ultraviolet-proof effect can be shown; and has an excellent effect in improving dispersibility and stability of a dosage form by applying a dual gelling system comprising an oil thickening agent and a nonionic thickening agent.

Description

Technical Field

[0001] The present invention relates to a cosmetic composition for stabilizing a water-dispersible organic-inorganic composite for UV protection by applying a dual gelling system, and more particularly to a cosmetic composition having excellent UV protection effect, excellent dispersibility and formulation stability as a UV protection component composed of the organic-inorganic composite is stabilized within the formulation. Background Art

[0002] Continuous exposure to ultraviolet light accelerates aging and can lead to skin damage. Ultraviolet A (UVA), classified as long-wavelength ultraviolet radiation (UVB), has a longer wavelength than other UVB rays and can reach the dermis, causing darkening and photoaging. To maintain healthy skin, a UV blocker that effectively blocks UVB rays in the long-wavelength range is needed.

[0003] UV blockers are mainly divided into inorganic and organic UV blockers. Inorganic UV blockers generally exhibit a significant whitening effect due to their characteristic high refractive index, resulting in a rough, dry, and degraded feel when applied. These inorganic UV blockers tend to be opaque or whitish, resulting in poor adhesion when applied to the skin, a thick, unnatural appearance, and inconvenience in matching the skin tone. Organic UV blockers offer the advantages of less whitening and a wide range of absorption wavelengths, but they can cause skin problems and, in sensitive skin, may cause side effects such as eye pain when applied around the eyes. Furthermore, because inorganic and organic UV blockers absorb different wavelengths, one approach to effectively block UV rays across a wider range of wavelengths is to combine organic and inorganic UV blockers. However, combining organic and inorganic components in a single formulation is difficult because thermodynamic instabilities within the formulation must be controlled. In particular, in emulsions containing both an oil and water phase, most organic UV blockers are oil-soluble, resulting in minimal UV protection in the water phase, making it difficult to uniformly block UV rays. Furthermore, most water-soluble organic UV blockers ionize in water, becoming charged. Therefore, when used with inorganic UV blockers, which partially dissociate in water and become charged, coagulation of opposite charges can occur, impairing formulation stability.

[0004] Therefore, in order to effectively block ultraviolet rays in a wide wavelength range, the inventors of the present invention used a complex of organic-inorganic ultraviolet blocking ingredients and continued to study how to stabilize it within the dosage form. As a result, by optimizing the mixing ratio of the dispersant and the thickener, they completed a cosmetic composition that stabilizes the complex of organic-inorganic ultraviolet blocking ingredients within the dosage form.

[0005] Prior art literature

[0006] Patent Literature

[0007] (Patent Document 0001) KR10-2022-0054447A Summary of the Invention

[0008] Problems to be solved by the invention

[0009] An object of the present invention is to provide a cosmetic composition for stabilizing a water-dispersible organic-inorganic composite for UV protection by using a dual gelling system.

[0010] The technical problems of the present invention are not limited to the technical problems mentioned above, and those skilled in the art can clearly understand other technical problems not mentioned based on the following description.

[0011] Means used to solve problems

[0012] According to an embodiment of the present invention, a cosmetic composition is provided. The cosmetic composition stabilizes a water-dispersible organic-inorganic composite for UV protection by applying a dual gelling system. The cosmetic composition comprises a dispersant and two or more thickeners. The dispersant comprises a water-soluble dispersant. The two or more thickeners comprise an oil thickener and a nonionic thickener. The UV protection ingredient comprises terephthalylidene dicamphor sulfonic acid, titanium dioxide, aluminum hydroxide, and aminopropyl triethoxysilane.

[0013] The cosmetic composition is in the form of an emulsion comprising an aqueous phase and an oily phase. The aqueous phase comprises a nonionic thickener, and the oily phase may comprise an oily thickener.

[0014] The water-soluble dispersant may include an anionic dispersant.

[0015] The water-soluble dispersant may include a glutamic acid-based dispersant.

[0016] The nonionic thickener may include poloxamer-type substances.

[0017] The two or more thickeners may further include an inorganic thickener.

[0018] The cosmetic composition may be of a water-in-oil (W / O) type.

[0019] The cosmetic composition may be in the form of a lotion.

[0020] Effects of the Invention

[0021] The cosmetic composition of the present invention, which stabilizes a water-dispersible organic-inorganic composite for UV protection by using a dual gelling system, is composed of an organic-inorganic composite, and thus can stabilize the UV protection component that can block UV rays in a wide wavelength range within the dosage form, thereby exhibiting an excellent UV protection effect.

[0022] The cosmetic composition of the present invention, which stabilizes the water-dispersible organic-inorganic composite for UV protection by applying a dual gelling system, has excellent dispersibility and excellent formulation stability, and thus it can be easily stored for a long period of time.

[0023] The cosmetic composition of the present invention, which stabilizes a water-dispersible organic-inorganic composite for UV protection by applying a dual gelling system, contains a nonionic thickener and an oil thickener, thereby providing excellent use feeling such as non-stickiness and light spreadability. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more fully understand the drawings cited in the detailed description of the present invention, a brief description of each drawing will be provided.

[0025] Figure 1a Shown are photographs of dosage forms of cosmetic compositions according to examples of the present invention.

[0026] Figure 1b Shown are photos of skin taken after applying a cosmetic composition according to an example of the present invention to the skin. DETAILED DESCRIPTION

[0027] Unless otherwise defined, all technical terms and scientific terms used in this specification have the same meaning as those generally understood by those of ordinary skill in the art to which the present invention belongs. Generally speaking, the nomenclature used in this specification is well known and commonly used in the art. In addition, in the process of describing the embodiments of the present invention, when it is believed that the detailed description of the relevant known formations or functions will confuse the understanding of the embodiments of the present invention, its detailed description will be omitted. In addition, the embodiments of the present invention will be described below, but the technical ideas of the present invention are not limited thereto or are not limited thereto, and can be modified and implemented in various ways by those of ordinary skill in the art.

[0028] In this specification, when a part includes a certain component, it means that unless otherwise stated, other components may also be included, rather than excluding other components. In this specification, the term "and / or" includes a combination of multiple related items or any one of the multiple related items.

[0029] According to embodiments of the present invention, a water-dispersible organic-inorganic composite cosmetic composition for UV protection stabilized by a dual-gelling system exhibits high stability due to the excellent water dispersibility of the UV protection component and exhibits excellent UV blocking effects against a wide range of wavelengths. Specifically, the wide-wavelength UV radiation can include UVA1 (UV radiation with a wavelength of 340 to 400 nm), UVA2 (UV radiation with a wavelength of 320 to 340 nm), and UVB (UV radiation with a wavelength of 280 to 320 nm). Figure 1a 1 shows a photograph of a dosage form of a cosmetic composition according to an embodiment of the present invention. Figure 1a As shown, it can be confirmed that the cosmetic composition of the present invention contains a nonionic thickener in the water phase and an oil thickener and an inorganic thickener in the oil phase, and thus has a non-sticky and light feel during use. Figure 1b Shown is the Figure 1a After applying the cosmetic composition shown, a photo of the skin coated with the composition was taken. Figure 1b It was confirmed that the cosmetic composition of the present invention not only does not show a whitening phenomenon when applied to the skin, but also shows an excellent feeling of use with non-stickiness and light spreadability.

[0030] As used herein, a "dual gelling system" refers to a system in which different thickeners are used in both the aqueous and oil phases to form a water-based gel network in the aqueous phase and an oil-based gel network in the oil phase. This improves the stability of the ingredients contained in both the aqueous and oil phases, while also preventing separation between the aqueous and oil phases, thereby enhancing the stability of the dosage form and maintaining consistent texture and effects over time. In particular, the gel network in the aqueous phase not only improves the dispersibility of the organic-inorganic complex but also collapses upon application to the skin, providing an immediate moisturizing effect.

[0031] According to an embodiment of the present invention, a cosmetic composition for stabilizing a water-dispersible organic-inorganic composite for UV protection by applying a dual gelling system comprises a dispersant and two or more thickeners. The water-dispersible organic-inorganic composite for UV protection may include an organic-inorganic composite powder containing a water-soluble organic UV shielding agent. Specifically, the organic-inorganic composite powder may include an organic-inorganic composite powder in which a water-soluble organic UV shielding agent and an inorganic UV shielding agent are chemically bonded. In one embodiment, the water-dispersible organic-inorganic composite for UV protection may include terephthalylidene dicamphor sulfonic acid*titanium dioxide*aluminum hydroxide*aminopropyl triethoxysilane (TDST) (where * represents a combination of ingredients). In this case, the dispersant may include a water-soluble dispersant, and the two or more thickeners may include an oil thickener and a nonionic thickener.

[0032] The water-dispersible organic-inorganic composite for UV protection described herein comprises terephthalylidene dicamphor sulfonic acid, titanium dioxide, aluminum hydroxide, and aminopropyl triethoxysilane (TDST), a novel organic-inorganic composite formed from terephthalylidene dicamphor sulfonic acid (TDSA), a water-soluble organic UV protection component; titanium dioxide and aluminum hydroxide, inorganic UV protection components; and aminopropyl triethoxysilane. TDST is a chemically bonded composite of all four components, providing excellent UV protection across a wide range of wavelengths, including UVA1, UVA2, and UVB. In specific embodiments, the TDST can be dispersed in the aqueous phase of a water-in-oil emulsion to enhance the UV protection delivered through the aqueous phase.

[0033] In another embodiment, as the water-dispersible organic-inorganic composite of the present invention, a water-dispersible organic-inorganic composite containing TDST and titanium dioxide or zinc oxide as an inorganic UV blocking agent component can also be used.

[0034] According to an embodiment of the present invention, a cosmetic composition for stabilizing a water-dispersible organic-inorganic composite for UV protection using a dual gelling system is an emulsion formulation comprising an aqueous phase and an oily phase. The aqueous phase may include a nonionic thickener, and the oily phase may include an oily thickener. Therefore, by forming a dual gelling system with different thickeners in the aqueous and oily phases, the formulation stability and long-term stability can be significantly improved.

[0035] The water-soluble dispersant of the present invention can play the role of uniformly dispersing TDST in the aqueous phase and ensuring the long-term stability of the dosage form. Specifically, the water-soluble dispersant can include anionic dispersants, more specifically, glutamic acid-based dispersants. As an example of the component included by the water-soluble dispersant, it can be selected from one or more of the group consisting of sodium stearoyl glutamate (Sodium Stearoyl Glutamate), potassium cetyl phosphate (Potassium cetyl phosphate), potassium stearoyl glutamate (Potassium Stearoyl Glutamate), disodium octanoyl glutamate (Disodium Capryloyl Glutamate) and sodium dilauramido glutamide lysine (Sodium Dilauramido glutamide Lysine). However, it is not limited thereto.

[0036] In embodiments, the cosmetic composition may include 0.005 to 4.5% by weight of a water-soluble dispersant, specifically 0.005 to 4% by weight, more specifically 0.005 to 3.5% by weight, and most specifically 0.005 to 3% by weight, based on the total weight of the cosmetic composition. If the content of the water-soluble dispersant is less than 0.005% by weight, the UV protection ingredient may not be evenly dispersed in the aqueous phase. If the content exceeds 4.5% by weight, the dosage form itself may not form.

[0037] The nonionic thickener of the present invention forms the viscosity of the aqueous phase to improve the stability of the TDST dispersed in the aqueous phase, thereby playing a role in maintaining the dosage form stably for a long time.

[0038] In an embodiment, the nonionic thickener may include a poloxamer-based substance. The poloxamer-based substance may include a substance selected from the group consisting of poloxamer 105, poloxamer 124, poloxamer 181, poloxamer 182, poloxamer 184, poloxamer 185, poloxamer 188, poloxamer 333, poloxamer 403, poloxamer 407, poloxamer 331, poloxamer 338, poloxamer 235, poloxamer 234, poloxamer 217, poloxamer 401, poloxamer 215 ... The invention also includes one or more of the group consisting of poloxamer 101, poloxamer 123, poloxamer 237, poloxamer 238, poloxamer 334, poloxamer 335, poloxamer 108, poloxamer 122, poloxamer 183, poloxamer 212, poloxamer 231, poloxamer 282, poloxamer 284, poloxamer 288, and poloxamer 402, and specifically, at least one of poloxamer 188 and poloxamer 407. When the poloxamer-based substances are included, other nonionic thickener components may also be included. However, when the additional component contains a cationic thickener component, aggregation may occur, making it impossible to form a dosage form.

[0039] In embodiments, the cosmetic composition may include 0.01 to 8 wt% of a nonionic thickener, specifically 0.01 to 7 wt%, more specifically 0.01 to 6 wt%, and most specifically 0.01 to 5 wt%, based on the total weight of the cosmetic composition. If the nonionic thickener content is less than 0.01 wt%, the UV protection ingredient may not be uniformly dispersed in the aqueous phase. If the content exceeds 8 wt%, the formulation may be difficult to form due to high viscosity.

[0040] In the embodiments, the oil thickener can improve the long-term stability and feel of the dosage form by adjusting the viscosity of the oil phase.

[0041] In an embodiment, the cosmetic composition may include an oil thickener in an amount of 0.1 to 14 wt %, specifically 0.1 to 12 wt %, more specifically 0.1 to 11 wt %, and most specifically 0.1 to 10 wt %, based on the total weight of the cosmetic composition. When the content of the oil thickener is less than 0.1 wt %, the long-term stability of the formulation may be reduced. When the content exceeds 14 wt %, the viscosity of the oil phase may increase excessively, making it impossible to form a formulation, and the problem of reduced feel during use due to excessive stickiness may occur.

[0042] In embodiments, the dual gel system of the present invention is formed by combining a nonionic thickener for the aqueous phase with an oil thickener for the oil phase, and is not limited by the composition of the oil thickener. In specific embodiments of the present invention, the oil thickener may be included without limitation, as long as it is commonly used in the ingredients of cosmetic compositions. Examples of the oil thickener include dextrin behenate, dextrin laurate, dextrin palmitate, dextrin myristate, dextrin palmitate / ethyl hexanoate, dextrin palmitate / hexyl decanoate, dextrin palmitate / stearate, stearoyl inulin, sucrose laurate, microcrystalline cellulose, polyamide-3, polyamide-8, HDI / trimethylol hexyllactone crosspolymer, VP / eicosene copolymer, and the like. Copolymer), Glyceryl Tribehenate / Isostearate / Eicosadioate, and Glyceryl Ethylhexanoate / Stearate / Adipate. However, it is not limited thereto.

[0043] In an embodiment, the two or more thickeners may further include an inorganic thickener. The inorganic thickener may be included in the oil phase to adjust the viscosity of the oil phase, thereby improving the long-term stability and feel of the dosage form.

[0044] In an embodiment, the inorganic thickener may be included in an amount of 0.05 to 2.5 wt %, specifically 0.05 to 2.3 wt %, more specifically 0.05 to 2.1 wt %, and most specifically 0.05 to 2.0 wt %, based on the total weight of the cosmetic composition. When the content of the inorganic thickener is less than 0.05 wt %, the long-term stability of the formulation may be reduced. When the content exceeds 2.5 wt %, the viscosity of the oil phase may increase excessively, making the formulation impossible to form, and the problem of reduced feel during use due to excessive stickiness may occur.

[0045] In an embodiment, an inorganic thickener may be included without limitation, as long as it is commonly used in the ingredients of a cosmetic composition. As an example of the inorganic thickener, one or more selected from the group consisting of disteardimonium hectorite, hectorite, quaternium-18 hectorite, stearalkonium hectorite, dihydrogenated tallow benzylmethyl ammonium hectorite, bentonite, quaternium-90 bentonite, quaternium-18 bentonite, and stearalkonium bentonite may be included. However, it is not limited thereto.

[0046] The cosmetic composition for stabilizing a water-dispersible organic-inorganic composite for UV protection using a dual-gel system according to the present invention may further include a UV absorber. This provides UV protection in regions other than the UV absorption region of the TDST, thereby providing excellent UV protection across a wider wavelength range.

[0047] The cosmetic composition for stabilizing the water-dispersible organic-inorganic composite for UV protection by applying a dual gelling system of the present invention may further contain an ultraviolet absorber component selected from, for example, para-aminobenzoic acid, para-aminobenzoic acid monoglyceride, N,N-dipropoxy para-aminobenzoic acid ethyl ester, N,N-diethoxy para-aminobenzoic acid ethyl ester, N,N-dimethyl para-aminobenzoic acid ethyl ester, N,N-dimethyl para-aminobenzoic acid butyl ester, N,N-dimethyl ...ethyl ester, N,N-dimethyl para-aminobenzoic acid ethyl ester, N,N-dimethyl para-aminobenzoic acid ethyl ester, N,N-dimethyl para-aminobenzoic acid ethyl ester, N,N-dimethyl para-aminobenzoic acid ethyl ester, N,N-dimethyl para-aminobenzoic acid ethyl ester, ester) and the like; anthranilic acid-based ultraviolet absorbers such as homomenthyl-N-acetylanthranilate; salicylic acid-based ultraviolet absorbers such as salicylic acid and its sodium salt, amyl salicylate, menthyl salicylate, homomenthylsalicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, and p-isopropanol phenylsalicylate;Octyl cinnamate, ethyl-4-isopropyl cinnamate, methyl-2,5-diisopropyl cinnamate, ethyl-2,4-diisopropylcinnamate, methyl-2,4-diisopropyl cinnamate, propyl-p-methoxy cinnamate, isopropyl-p-methoxy cinnamate, isoamyl-p-methoxycinnamate, 2-Ethyl hexyl-p-methoxy cinnamate (para-methoxy Octyl Cinnamate) Cinnamate), 2-ethoxyethyl-p-methoxy cinnamate (Cinoxate), cyclohexyl-p-methoxy cinnamate, ethyl-α-cyano-β-phenyl cinnamate, 2-ethylhexyl-α-cyano-β-phenylcinnamate (Octocrylene), glyceryl mono-2-ethylhexanoyl-diparamethoxycinnamate, ferulic acid and its derivatives, etc.2,4-dihydroxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2',4,4'-tetrahydroxybenzophenone 2-Hydroxybenzophenone), 2-hydroxy-4-methoxybenzophenone (OXYBENZONE-3), 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2-Ethyl hexyl-4'-phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octoxybenzophenone, 4-hydroxy-3-carboxybenzophenone Benzophenone-based UV absorbers such as benzophenone; 3-(4'-methyl benzylidene)-d,l-camphor, 3-benzylidene-d,l-camphor; diethylamino hydroxybenzoyl hexylbenzoate; 2-phenyl-5-methylbenzoxazole; 2,2'-hydroxy-5-methylphenylBenzotriazole; 2-(2'-hydroxy-5'-t-Octyl Phenyl)Benzotriazole;2-(2'-hydroxy-5'-methylphenyl)benzotriazole; Diethyl hexylbutamido triazone; Ethyl hexyl triazone; Dibenzalazine; Dianisyl methane; 5-(3,3-dimethyl-2-norbornene)-3-pentan-2-one; Dibenzoylmethane derivatives such as 4-t-Butylmethoxydibenzoylmethane; Octyl triazone; Urocanic acid and ethyl urocanate 2-(2'-hydroxy-5'-methylphenyl)benzotriazole, 1-(3,4-dimethoxyphenyl)-4,4-dimethyl-1,3-pentanedione, 2-ethylhexyl dimethoxybenzylidene dioxo imidazolidinpropionic acid, phenylbenzimidazole sulfonic acid, terephthalylidenedicamphor sulfonic acid, drometrizole trisiloxane, anthranilic acid methyl ester The invention also includes a group consisting of methyl, rutin and its derivatives, and oryzanol and its derivatives. Specifically, an organic UV absorber component, more specifically an oil-soluble organic UV absorber component, can be further used to minimize whitening and provide an excellent feel. Furthermore, the product can provide UV protection in regions other than the absorption wavelength of TDST.

[0048] In an embodiment, the cosmetic composition for stabilizing a water-dispersible organic-inorganic composite for UV protection by applying a dual gelling system of the present invention may further comprise an inorganic UV absorbent component within the range not impairing the object and effect of the present invention.

[0049] In an embodiment, the cosmetic composition for stabilizing the water-dispersible organic-inorganic composite for UV protection by applying a dual gelling system of the present invention may further comprise a moisturizer, a preservative, or a functional ingredient.

[0050] The moisturizer provides moisture to the skin or maintains moisture of the skin and provides a continuous moisturizing feeling. It is preferably a water-soluble component, and examples thereof include glycerin, butylene glycol, propylene glycol, dipropylene glycol, methylpropanediol, pentylene glycol, glycereth-26, propandiol, sorbitol, diglycerin, etc., but are not limited thereto.

[0051] The preservative is used to improve the preservation effect, and examples thereof include ethylhexylglycerin, 1,2-hexanediol, etc., but are not limited thereto.

[0052] The functional ingredients may be mixed with various ingredients according to the purpose of the cosmetic composition, and include, for example, wrinkle improving agents, whitening functional ingredients, pigmentation functional ingredients, skin soothing functional ingredients, and sebum or pore management functional ingredients.

[0053] In addition, the cosmetic composition of the present invention for stabilizing the water-dispersible organic-inorganic composite for UV protection by applying a dual gelling system may further include ingredients contained in conventional cosmetic compositions, such as emulsifiers, emulsion stabilizers, skin conditioning agents, ion chelating agents, disinfectants, pH regulators, antioxidants, alcohol, plant extracts, fragrances, skin feel regulators, emollients, etc.

[0054] The mixing amounts of the components are not particularly limited and can be easily selected by those skilled in the art within a range that does not impair the purpose and effects of the present invention.

[0055] The cosmetic composition for stabilizing a water-dispersible organic-inorganic composite for UV protection by applying a dual gelling system according to an embodiment of the present invention can be a water-in-oil type. The water-in-oil type refers to a state in which the water phase is dispersed in the oil phase in the form of particles, and can include water-in-oil (W / O) and multiple emulsion formulations such as oil-in-water-in-oil (O / W / O). In one embodiment, the cosmetic composition can be provided in the form of an emulsion formulation containing a water-in-oil emulsion, a cream formulation, a low-viscosity liquid formulation, or a fluid formulation, and specifically, can be provided in an emulsion formulation.

[0056] The cosmetic composition for stabilizing a water-dispersible organic-inorganic composite for UV protection using a dual-gelling system according to an embodiment of the present invention can be in the form of a gel. A gel formulation is a formulation that exhibits sufficient viscosity and elasticity and fluidity, solidifying like a solid but flowing like a liquid under specific pressure or during movement. More specifically, the cosmetic composition can be prepared in the form of an oleogel.

[0057] The cosmetic composition of the water-dispersible organic-inorganic composite stabilized for UV protection by applying a dual gelling system according to the present invention can be provided in the form of a dosage form conventionally prepared in the art. For example, it can be formulated in the form of a water-dispersible dosage form dispersed in an aqueous phase, an oil-in-water (O / W), or a water-in-oil-in-water (W / O / W) emulsion. However, without limitation thereto, the composition can also be provided in the form of various dosage forms such as a solution, a suspension, an emulsion, a solid, an oil, a powder, a paste, or a foam aerosol, a spray, or the like.

[0058] Hereinafter, examples and experimental examples are provided to more specifically illustrate the present invention, but the present invention is not limited thereto.

[0059] Experimental Example 1. Comparative experiment based on the content of water-soluble dispersant

[0060] (1) Preparation of Examples and Comparative Examples

[0061] As shown in Table 1 below, in order to confirm the effect according to the content of water-soluble dispersant in the present invention, embodiments and comparative examples of water-in-oil type were prepared. Specifically, as water-soluble dispersant, one or two of sodium stearoyl glutamate, potassium cetyl phosphate, potassium stearoyl glutamate, disodium octanoyl glutamate and sodium di(lauryl amide glutamine) lysine were used, as nonionic thickener, poloxamer 188 was used, as oil thickener, dextrin palmitate and polyamide-3 (Polyamide-3) were used, as inorganic thickener, disteardimonium hectorite (Disteardimonium Hectorite) was used, as water-soluble organic UV-blocking agent, terephthalylidene dicamphor sulfonic acid (TDSA) was used. The content of the water-soluble dispersant was changed, and the content of the remaining components remained consistent. The content of Table 1 below is by weight.

[0062] Table 1

[0063]

[0064]

[0065] The specific preparation method is as follows.

[0066] The emulsifier, UV absorber, and emollient components of the oil phase were dissolved by heating. The oil thickener and inorganic thickener components were uniformly dispersed in the oil phase using an Agi mixer, and then cooled to room temperature to prepare an oil phase mixture.

[0067] The components corresponding to the aqueous phase were dissolved and dispersed by a paddle mixer (Agi Mixer) at high temperature and then cooled to room temperature to prepare a mixture of the aqueous phase.

[0068] Then, the oil phase mixture was stirred using an ULTRA series HOMO MIXER while slowly adding the water phase mixture to complete the water-in-oil type Examples and Comparative Examples.

[0069] (2) Evaluation of dosage form formation, aqueous dispersibility, and long-term stability

[0070] The Examples and Comparative Examples prepared using the ingredients and contents shown in Table 1 were evaluated for their formation and stability.

[0071] When evaluating the formation of the dosage form and the dispersion of the aqueous phase, visually confirm whether a uniform water-in-oil dosage form is formed and whether aggregates appear without separation of the oil and aqueous phases. When evaluating long-term stability, repeat the process of cooling from high temperature (40°C), room temperature (25°C), low temperature (5°C), cooling from high temperature to room temperature, low temperature, then heating from low temperature to room temperature, and high temperature. The product is then stored for 3 months and observed to see whether it still maintains the same dosage form as just prepared. If the dosage form stability is not maintained in any of the four temperature environments, it is judged to be unqualified.

[0072] The evaluation results are shown in Table 2 below.

[0073] Table 2

[0074]

[0075] Table 2 shows that in Examples 1 to 8, which contained appropriate amounts of water-soluble dispersants, the dosage forms were neatly formed, TDST was well dispersed in the aqueous phase, and long-term stability was excellent. On the other hand, in Comparative Example 1, which contained a small amount of water-soluble dispersant, the dosage form was formed and long-term stability was excellent, but TDST was not well dispersed in the aqueous phase. In Comparative Example 2, which contained an excessive amount of water-soluble dispersant, the dosage form itself was not formed, and properties were observed during long-term storage that were completely different from those immediately after preparation. The results in Comparative Example 2 are believed to be due to an excessive increase in the HLB value caused by the excessive amount of dispersant.

[0076] (3) Measurement of UV protection effect and transmittance

[0077] To confirm the UV protection effect of the Examples and Comparative Examples, the sun protection factor (SPF) was measured in vitro. The specific measurement method is as follows.

[0078] Examples and comparative examples were tested at 2 mg / cm 2 The amount of the coating was evenly applied on a PMMA plate for 30 seconds and then dried in the dark for 15 minutes to prepare a sample. The in vitro SPF value was measured using a UV-2000S in vitro ultraviolet analyzer from Labsphere (Labsphere Optics).

[0079] The measurement results of the measurement method are shown in Table 3.

[0080] Table 3

[0081]

[0082]

[0083] Table 3 shows that all Examples, where TDST has high aqueous dispersibility, measured high SPF values. However, Comparative Example 1, where aqueous dispersibility decreased due to a low content of a water-soluble dispersant, measured SPF values ​​lower than those of the Examples. This suggests that excellent aqueous dispersibility can also be evaluated as excellent UV protection.

[0084] Therefore, it was confirmed that the inclusion of a water-soluble dispersant in an appropriate amount is an important component for forming a dosage form of a cosmetic composition having excellent water-phase dispersibility stably for a long period of time, which is the object of the present invention.

[0085] Experimental Example 2. Comparative experiment based on nonionic thickener content

[0086] (1) Preparation of Examples and Comparative Examples

[0087] As shown in Table 4 below, to confirm the effects of the inclusion and content of a nonionic thickener in the present invention, examples and comparative examples were prepared using the same preparation method as in Experimental Example 1. Specifically, one or two of Poloxamer 188, Poloxamer 407, HydroxypropylMethylcellulose Stearoxy Ether, and Polyether-1 were used as nonionic thickeners. To confirm whether the objectives of the present invention can be achieved using a cationic thickener instead of a nonionic thickener, Polyquaternium-37 was used as a cationic thickener. The remaining components and contents were the same as in Example 1. The units in Table 4 are weight percent.

[0088] Table 4

[0089]

[0090]

[0091] (2) Evaluation of whether the dosage form is formed, aqueous phase dispersibility and stability

[0092] The Examples and Comparative Examples prepared using the ingredients and contents shown in Table 4 were evaluated for their dosage form formation and stability using the same method as in Experimental Example 1.

[0093] The evaluation results are shown in Table 5 below.

[0094] Table 5

[0095]

[0096] Table 5 shows that Examples 9 to 12, which all contained appropriate amounts of nonionic thickeners, all exhibited neat dosage form formation, good dispersion of TDST in the aqueous phase, and excellent long-term stability. On the other hand, Comparative Example 3, which did not contain a nonionic thickener, exhibited poor aqueous dispersibility of TDST. Comparative Example 4, which contained a cationic thickener, exhibited aggregation, preventing the dosage form from forming. The resulting long-term storage exhibited properties completely different from those immediately after preparation. Comparative Example 5, which contained an excessive amount of nonionic thickener, exhibited excessively high aqueous viscosity, preventing the dosage form from forming. The resulting long-term storage exhibited properties completely different from those immediately after preparation.

[0097] Therefore, it was confirmed that the inclusion of a nonionic thickener in an appropriate amount is an important component for forming a dosage form of a cosmetic composition having excellent aqueous phase dispersibility stably for a long period of time, which is the object of the present invention.

[0098] Experimental Example 3. Comparative experiment based on oil thickener content

[0099] (1) Preparation of Examples and Comparative Examples

[0100] As shown in Table 6 below, to confirm the effects of the presence and content of an oil thickener in the present invention, examples and comparative examples were prepared using the same preparation method as Experimental Example 1. Specifically, as the oil thickener, one or more of dextrin palmitate, polyamide-3, HDI / trimethylol hexyllactone crosspolymer, and VP / eicosene copolymer were used. The remaining components and contents were the same as in Example 1. The units in Table 6 are in weight percent.

[0101] Table 6

[0102]

[0103] (2) Evaluation of whether the dosage form is formed, aqueous phase dispersibility and stability

[0104] The Examples and Comparative Examples prepared using the ingredients and contents shown in Table 6 were evaluated for their dosage form formation and stability using the same method as in Experimental Example 1.

[0105] The evaluation results are shown in Table 7 below.

[0106] Table 7

[0107]

[0108] Table 7 shows that Examples 13 to 18, which contained appropriate amounts of oil thickener, all exhibited neat dosage form formation, good dispersion of TDST in the aqueous phase, and excellent long-term stability. On the other hand, in Comparative Example 6, which did not contain an oil thickener, no dosage form was formed. While Comparative Example 7, which contained a small amount of oil thickener, did form a dosage form and exhibited excellent aqueous dispersibility, its long-term stability was poor. In Comparative Example 8, which contained an excessive amount of oil thickener, the excessively high viscosity of the oil phase prevented the dosage form from forming properly, and long-term storage revealed properties that were completely different from those immediately after preparation.

[0109] Therefore, it was confirmed that the inclusion of an appropriate amount of an oil thickener is an important component for forming a dosage form of a cosmetic composition having excellent water-phase dispersibility stably for a long period of time, which is the object of the present invention.

[0110] Experimental Example 4. Comparative experiment based on the content of inorganic thickener

[0111] (1) Preparation of Examples and Comparative Examples

[0112] As shown in Table 8 below, to confirm the effects of the presence and content of an inorganic thickener in the present invention, examples and comparative examples were prepared using the same preparation method as Experimental Example 1. Specifically, one of disteardimonium hectorite and stearalkonium hectorite was used as the inorganic thickener. The remaining components and contents were the same as in Example 1. Table 8 shows units in weight %.

[0113] Table 8

[0114]

[0115] (2) Evaluation of whether the dosage form is formed, aqueous phase dispersibility and stability

[0116] The Examples and Comparative Examples prepared using the ingredients and contents shown in Table 8 were evaluated for their dosage form formation and stability using the same method as in Experimental Example 1.

[0117] The evaluation results are shown in Table 9 below.

[0118] Table 9

[0119]

[0120]

[0121] Table 9 shows that Examples 19 to 23, which contained appropriate amounts of inorganic thickener, all exhibited neat dosage form formation, good dispersion of TDST in the aqueous phase, and excellent long-term stability. On the other hand, Comparative Example 9, which did not contain an inorganic thickener, did not form a dosage form. While Comparative Example 10, which contained a small amount of inorganic thickener, did form a dosage form and exhibited excellent aqueous dispersibility, it exhibited poor long-term stability. In Comparative Example 11, which contained an excessive amount of inorganic thickener, the excessively high viscosity of the oil phase prevented the dosage form from forming properly, and long-term storage revealed properties that were completely different from those immediately after preparation.

[0122] Therefore, it was confirmed that the inclusion of an appropriate content of an inorganic thickener is an important component for forming a dosage form of a cosmetic composition having excellent water-phase dispersibility stably for a long period of time, which is the object of the present invention.

[0123] While specific portions of the present invention have been described in detail above, it should be clear to those skilled in the art that these specific techniques are merely preferred embodiments and are not intended to limit the scope of the present invention. Therefore, the true scope of the present invention should be defined by the appended claims and their equivalents.

Claims

1. A cosmetic composition that stabilizes an ultraviolet protection component, characterized in that: Contains a dispersant and two or more thickeners, The dispersant includes a water-soluble dispersant, The two or more thickeners include oil thickeners and nonionic thickeners, The UV protection ingredients include terephthalylidene dicamphor sulfonic acid*titanium dioxide*aluminum hydroxide*aminopropyltriethoxysilane.

2. The cosmetic composition according to claim 1, characterized in that The cosmetic composition is an emulsion formulation comprising an aqueous phase and an oily phase, The aqueous phase contains a nonionic thickener, The oil phase comprises an oil thickener.

3. The cosmetic composition according to claim 1, characterized in that The water-soluble dispersant is included in an amount of 0.005 wt % to 4.5 wt % based on the total weight of the cosmetic composition.

4. The cosmetic composition according to claim 1, characterized in that The cosmetic composition comprises 0.01 wt % to 8 wt % of the nonionic thickener based on the total weight of the cosmetic composition.

5. The cosmetic composition according to claim 1, wherein The water-soluble dispersant includes an anionic dispersant.

6. The cosmetic composition according to claim 1, characterized in that The water-soluble dispersant includes a glutamic acid-based dispersant.

7. The cosmetic composition according to claim 1, wherein The nonionic thickener includes poloxamer-type substances.

8. The cosmetic composition according to claim 7, characterized in that The poloxamer substances include poloxamer 105, poloxamer 124, poloxamer 181, poloxamer 182, poloxamer 184, poloxamer 185, poloxamer 188, poloxamer 333, poloxamer 403, poloxamer 407, poloxamer 331, poloxamer 338, poloxamer 235, poloxamer 234, poloxamer 217, poloxamer 4 01, one or more selected from the group consisting of poloxamer 215, poloxamer 101, poloxamer 123, poloxamer 237, poloxamer 238, poloxamer 334, poloxamer 335, poloxamer 108, poloxamer 122, poloxamer 183, poloxamer 212, poloxamer 231, poloxamer 282, poloxamer 284, poloxamer 288, and poloxamer 402.

9. The cosmetic composition according to claim 1, characterized in that The two or more thickeners also include an inorganic thickener.

10. The cosmetic composition according to claim 1, characterized in that The cosmetic composition comprises 0.1 wt % to 14 wt % of the oil thickener based on the total weight of the cosmetic composition.

11. The cosmetic composition according to claim 9, characterized in that The cosmetic composition comprises 0.05 wt % to 2.5 wt % of the inorganic thickener based on the total weight of the cosmetic composition.

12. The cosmetic composition according to claim 1, characterized in that The cosmetic composition is of a water-in-oil type.

13. The cosmetic composition according to claim 1, characterized in that The cosmetic composition is in the form of an emulsion.

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