Composition for preventing hair loss and strengthening hair and scalp preparation

Abstract

The invention provides a composition for preventing hair loss and strengthening hair and a scalp preparation, the composition comprises the following raw materials in parts by weight: 10-15 parts of ageratum conyzoides leaf extract, 5-10 parts of lactobacillus / acerola cherry fermentation product, 10-15 parts of pomegranate bark / fruit extract and 6-10 parts of panax japonicus root extract. The composition further comprises 4-6 parts of rosa damascena flower extract and 4-6 parts of daffodil flower extract. The composition for preventing hair loss and fixing hair can inhibit hair loss, improve the hair follicle environment, nourish scalp and promote hair growth, and has good hair loss preventing and fixing effects. Active substances in herbaceous plants can be effectively enriched to the maximum extent through a specific extraction method, and the obtained composition is small in irritation to scalp, safe, mild and good in application prospect.

Description

Technical Field

[0001] The present invention relates to the technical field of daily chemical products, and in particular to a composition and a scalp preparation for preventing hair loss and strengthening hair. Background Art

[0002] Hair loss refers to the loss of hair. Due to factors such as overactive sebaceous glands and clogged pores, the normal growth environment of hair is disrupted, preventing normal hair growth and resulting in severe hair loss and breakage. There are many causes of hair loss, including genetics, hormonal changes (pregnancy, childbirth, menopause), and other factors. Modern life is accelerating, and environmental pollution is increasing. More and more people are experiencing high levels of stress, overtime work, and late nights. Chronic stress and tension can lead to inflammation, which in turn affects the hair growth cycle and causes hair loss. Furthermore, stress can lead to excessive sebum secretion, atrophy of hair follicles, and poor metabolic function, further exacerbating hair loss and severely impacting daily life.

[0003] Currently, effective methods for promoting hair growth include alleviating inflammation and inhibiting excessive sebum secretion. Currently, the main medications used on the market for preventing and promoting hair loss include products such as finasteride and epristeride. These drugs are irritating and have significant side effects, and none of them can completely cure hair loss. They can also cause varying degrees of allergic reactions, and discontinuation of the medication may worsen the problem. Existing preparations based on purely traditional Chinese medicine formulas have variable effectiveness and slow onset of action. Furthermore, purely chemical formulations can be highly irritating to the scalp and pose safety concerns.

[0004] Therefore, the use of natural herbs to treat hair loss has become a research hotspot. It is of practical significance to seek a safe and mild scalp preparation that can prevent hair loss and strengthen hair without irritating the scalp. Summary of the Invention

[0005] In view of this, the present invention provides a composition and a scalp preparation for preventing hair loss and strengthening hair.

[0006] The technical solution of the present invention is achieved as follows: A composition for preventing hair loss and strengthening hair comprises the following raw materials, in parts by weight: 10-15 parts of ageratum conyzoides leaf extract, 5-10 parts of lactobacillus / acerola cherry fermentation product, 10-15 parts of pomegranate (punica granatum) bark / fruit extract, and 6-10 parts of panax japonicus root extract.

[0007] Furthermore, it also includes 4-6 parts of Rosa Damascena flower extract and 4-6 parts of Narcissus Pseudo-NARCISSUS flower extract.

[0008] Furthermore, the raw materials are included in parts by weight: 10-15 parts of ageratum leaf extract, 5-10 parts of lactobacillus / acerola cherry fermentation product, 10-15 parts of pomegranate bark / fruit extract and 6-10 parts of panax japonicus root extract, 4-6 parts of rosa damascena flower extract, and 4-6 parts of daffodil flower extract.

[0009] Furthermore, the preparation method of the Ageratum leaf extract comprises: (1) Repeatedly freeze-thaw fresh Ageratum leaves and crush them to obtain the material; (2) treating the material with citric acid, performing hot-press distillation, collecting the distillate, and concentrating it to a solid content of 6-8 mg / mL to obtain an Ageratum leaf extract; In step (1), the freeze-thaw cycle is performed 2-3 times, the freezing temperature is -20 to -10°C, and the freezing time is 1 to 2 hours; In step (2), the material-liquid ratio of the material to citric acid is 1:5-8 g / mL; the concentration of the citric acid is 5-8 wt%; In step (2), the temperature of the hot-pressing distillation is 80-90° C., the time is 20-40 min, and the pressure is 0.11-0.13 MPa.

[0010] Furthermore, the preparation method of the pomegranate bark / fruit extract comprises: (1) Crush fresh pomegranate bark / fruit, add it to complex enzyme solution 1, adjust the pH value to 6.0-6.5, and perform enzymolysis at 35-45°C for 40-60 minutes to obtain enzymatic hydrolyzate and residue; (2) adding the residue to the composite enzyme solution 2, adjusting the pH value to 7.5-8.0, performing enzymolysis at 50-60°C for 1-2 hours, collecting the enzymatic hydrolysate, combining the two enzymatic hydrolysates, concentrating under reduced pressure, and freeze-drying the obtained product to obtain a pomegranate bark / fruit extract; In step (1), the mass ratio of the pomegranate bark / fruit to the complex enzyme solution 1 is 1:10-20; the complex enzyme solution 1 comprises pectinase and desaccharidase in a mass ratio of 1:1-3, the enzymatic activity of the pectinase is 2500-3500 U / mL, and the enzymatic activity of the desaccharidase is 2000-3000 U / mL; In step (2), the mass ratio of the residue to the complex enzyme solution 2 is 1:10-15; the complex enzyme solution 2 comprises cellulase and amylase in a mass ratio of 1:0.8-1.8, the enzymatic activity of the cellulase is 2000-2500 U / mL, and the enzymatic activity of the amylase is 3000-3500 U / mL.

[0011] Furthermore, the Panax japonicus root extract is Panax japonicus root ethanol extract and / or Panax japonicus root ethyl acetate extract; The ethanol extract of Panax japonicus root is prepared by mixing Panax japonicus root and ethanol at a material-liquid ratio of 1:10-20 g / mL, extracting at 60-70° C. for 1-3 hours, and concentrating under reduced pressure to obtain the ethanol extract of Panax japonicus root; The ethyl acetate extract of Panax japonicus root is prepared by mixing Panax japonicus root and ethyl acetate at a material-liquid ratio of 1:8-12 g / mL, extracting at 50-60° C. for 1-2 hours, and concentrating under reduced pressure to obtain the ethyl acetate extract of Panax japonicus root.

[0012] Furthermore, the preparation method of the Rosa damascena flower extract comprises: (1) Crush the Rosa damascena flowers, add lactic acid bacteria, control the temperature at 25-30°C, and ferment in a sealed container for 5-7 hours; (2) adjusting the temperature to 33-36°C, adding yeast, and fermenting for 3-5 hours in a sealed container to obtain a fermentation product, which was then dried to obtain a Rosa damascena flower extract; In step (1), the lactic acid bacteria is at least one of Streptococcus thermophilus, Lactobacillus rhamnosus, Lactobacillus bulgaricus or Lactobacillus delbrueckii subspecies bulgaricus, and the amount added is 3%-5% of the weight of the Rosa damascena flower, and the number of viable bacteria is 1×10 7 CFU / mL; In step (2), the amount of yeast added is 6%-8% of the weight of the Rosa damascena flower, and the number of viable bacteria is 1×10 8 CFU / mL.

[0013] Furthermore, the preparation method of the daffodil flower extract includes: crushing the daffodil flower, placing it in a supercritical CO2 extraction device, extracting it at 20-30 MPa and 40-50° C. for 20-30 minutes, and concentrating under reduced pressure to obtain the daffodil flower extract.

[0014] The scalp preparation comprises the above-mentioned composition for preventing hair loss and strengthening hair, and acceptable auxiliary materials.

[0015] Furthermore, the concentration of the composition for preventing hair loss and strengthening hair is 5-10wt%; The scalp preparation includes shampoo or scalp essence.

[0016] Compared with the prior art, the present invention has the following beneficial effects: 1. The present invention extracts natural herbs through different specific extraction methods to obtain a composition consisting of ageratum leaf extract, pomegranate bark / fruit extract, panax japonicus root extract, rosa damascena flower extract, and daffodil flower extract, supplemented with a lactobacillus / acerola cherry fermentation product. The composition has a highly effective inhibitory effect on major microorganisms such as Malassezia furfur, inhibits hair loss, improves the hair follicle environment, nourishes the scalp, and promotes hair growth. It can be seen that the composition of the present invention has a good anti-hair loss and hair strengthening effect.

[0017] 2. The specific extraction method of the present invention can effectively and maximally enrich the active substances in the herbal plants. The resulting composition is less irritating to the scalp, safe and mild, and has good application prospects. DETAILED DESCRIPTION

[0018] In order to better understand the technical content of the present invention, specific examples are provided below to further illustrate the present invention.

[0019] Unless otherwise specified, the experimental methods used in the examples of the present invention are all conventional methods.

[0020] Unless otherwise specified, the materials, reagents, etc. used in the examples of the present invention can be obtained from commercial sources.

[0021] The lactobacillus / acerola fermentation product of the present invention was purchased from Qieke New Material Technology (Shanghai) Co., Ltd.

[0022] The lactic acid bacteria of the present invention are at least one of Streptococcus thermophilus, Lactobacillus rhamnosus, Lactobacillus bulgaricus or Lactobacillus delbrueckii subspecies bulgaricus, and the viable cell count is 1×10 7 CFU / mL.

[0023] The viable count of the yeast of the present invention is 1×10 8 CFU / mL.

[0024] Example 1 The composition for preventing hair loss and strengthening of this embodiment is composed of the following components: 13g of ageratum leaf extract, 8g of lactobacillus / acerola cherry fermentation product, 13g of pomegranate bark / fruit extract and 8g of panax japonicus root extract.

[0025] The preparation method of the above-mentioned Ageratum leaf extract comprises the following steps: Fresh ageratum leaves are repeatedly frozen and thawed 2-3 times, each freezing temperature is -20~-10℃, the time is 1-2 hours, and the material is crushed to obtain a material. The material is added to 5-8wt% citric acid at a material-liquid ratio of 1:5-8g / mL, and hot-pressure distillation is performed at 80-90℃ and 0.11-0.13MPa for 20-40 minutes. The distillate is collected and concentrated to a solid content of 6-8mg / mL to obtain the ageratum leaf extract.

[0026] The preparation method of the pomegranate bark / fruit extract comprises the following steps: (1) Fresh pomegranate bark / fruit is crushed and added to a composite enzyme solution 1, wherein the composite enzyme solution 1 comprises pectinase (enzyme activity of 2500-3500 U / mL) and desaccharidase (enzyme activity of 2000-3000 U / mL) in a mass ratio of 1:1-3, the mass ratio of pomegranate bark / fruit to composite enzyme solution 1 is 1:10-20, the pH value is adjusted to 6.0-6.5, and enzymolysis is carried out at 35-45°C for 40-60 minutes to obtain an enzymatic hydrolyzate and a residue; (2) The residue was added to the composite enzyme solution 2, with a mass ratio of the residue to the composite enzyme solution 2 of 1:10-15. The composite enzyme solution 2 included cellulase (enzyme activity of 2000-2500 U / mL) and amylase (enzyme activity of 3000-3500 U / mL) in a mass ratio of 1:0.8-1.8. The pH value was adjusted to 7.5-8.0, and the enzymolysis was carried out at 50-60°C for 1-2 hours. The enzymolysis solution was collected, the two enzymolysis solutions were combined, and the products were concentrated under reduced pressure. The obtained products were freeze-dried to obtain pomegranate bark / fruit extract.

[0027] The preparation method of the Panax japonicus root extract comprises the following steps: The root of Panax japonicus was crushed, added to 60% v / v ethanol at a solid-liquid ratio of 1:10-20 g / mL, extracted at 60-70° C. for 1-3 h, and concentrated under reduced pressure to obtain a Panax japonicus root extract.

[0028] Ageratum leaf extract, lactobacillus / acerola cherry fermentation product, pomegranate bark / fruit extract and japonica root extract are mixed to form a composition for preventing and strengthening hair loss.

[0029] Example 2 The composition for preventing hair loss and strengthening of this embodiment is composed of the following components: 10g of ageratum leaf extract, 5g of lactobacillus / acerola cherry fermentation product, 10g of pomegranate bark / fruit extract and 6g of panax japonicus root extract.

[0030] Other details are the same as those in Example 1.

[0031] Example 3 The composition for preventing hair loss and strengthening of this embodiment is composed of the following components: 15g of ageratum leaf extract, 10g of lactobacillus / acerola cherry fermentation product, 15g of pomegranate bark / fruit extract and 10g of panax japonicus root extract.

[0032] Other details are the same as those in Example 1.

[0033] Example 4 The composition for preventing and strengthening hair loss of this embodiment is composed of the following components: 13g of ageratum leaf extract, 8g of lactobacillus / acerola cherry fermentation product, 13g of pomegranate bark / fruit extract, 8g of japonica root extract, 5g of Rosa damascena flower extract and 5g of daffodil flower extract.

[0034] The preparation method of the Rosa damascena flower extract comprises the following steps: The dürzec rose flower is crushed, lactic acid bacteria are added in an amount of 3%-5% by weight of the dürzec rose flower, the temperature is controlled at 25-30°C, and sealed fermentation is carried out for 5-7 hours; the temperature is adjusted to 33-36°C, yeast is added in an amount of 6%-8% by weight of the dürzec rose flower, and sealed fermentation is carried out for 3-5 hours to obtain a fermentation product, which is dried to obtain a dürzec rose flower extract.

[0035] The preparation method of the daffodil flower extract comprises the following steps: The daffodil flowers are crushed, placed in a supercritical CO2 extraction device, extracted at 20-30 MPa and 40-50° C. for 20-30 min, and concentrated under reduced pressure to obtain the daffodil flower extract.

[0036] Ageratum leaf extract, lactobacillus / acerola cherry fermentation product, pomegranate bark / fruit extract, japonica root extract, rosa damascena flower extract and daffodil flower extract are mixed to form a composition for preventing and strengthening hair loss.

[0037] Other details are the same as those in Example 1.

[0038] Comparative Example 1 The composition of this comparative example is different from that of Example 4 in that it only includes ageratum leaf extract, lactobacillus / acerola cherry fermentation product, pomegranate bark / fruit extract, panax japonicus root extract and rosa damascena flower extract; the missing daffodil flower extract is distributed to the corresponding components according to the proportion of the other five substances.

[0039] Comparative Example 2 The composition of this comparative example is different from that of Example 4 in that it only includes ageratum leaf extract, pomegranate bark / fruit extract, panax japonicus root extract, rosa damascena flower extract and daffodil flower extract; the missing lactobacillus / acerola cherry fermentation product is distributed to the corresponding components according to the proportion of the other five substances.

[0040] Comparative Example 3 The composition of this comparative example is different from that of Example 4 in that it only includes ageratum leaf extract, lactobacillus / acerola cherry fermentation product, panax japonicus root extract, rosa damascena flower extract and daffodil flower extract; the missing pomegranate bark / fruit extract is distributed to the corresponding components according to the proportion of the other five substances.

[0041] Comparative Example 4 The composition of this comparative example is different from that of Example 4 in that it only includes ageratum leaf extract, lactobacillus / acerola cherry fermentation product, pomegranate bark / fruit extract, Rosa damascena flower extract and Daffodil flower extract; the missing Panax japonica root extract is distributed to the corresponding components according to the proportion of the other five substances.

[0042] Comparative Example 5 The composition of this comparative example is different from that of Example 4 in that it only includes ageratum leaf extract, lactobacillus / acerola cherry fermentation product, pomegranate bark / fruit extract, panax japonicus root extract and daffodil flower extract; the missing Rosa damascena flower extract is distributed to the corresponding components according to the proportion of the other five substances.

[0043] Comparative Example 6 The composition of this comparative example is different from that of Example 4 in that it only includes lactobacillus / acerola cherry fermentation product, pomegranate bark / fruit extract, japonica ginseng root extract, Rosa damascena flower extract and Daffodil flower extract; the missing Ageratum leaf extract is distributed to the corresponding components according to the proportion of the other five substances.

[0044] Comparative Example 7 The composition of this comparative example is different from that of Example 4 in that the extracts are both prepared by alcohol extraction.

[0045] Application Examples 1-4 The compositions for preventing hair loss and strengthening hair prepared in Examples 1-4 were prepared into scalp essences. The formula, calculated by mass percentage, was as follows: The composition for preventing hair loss and strengthening hair comprises 5wt% disodium EDTA 0.5wt%, phenoxyethanol 0.2wt%, glycerin 0.5wt%, and the balance water.

[0046] Comparative Application Examples 1-7 The compositions of Comparative Examples 1-7 were prepared into scalp essences, and the formulas were as follows based on mass percentage: The composition comprises 5wt%, 0.5wt% disodium EDTA, 0.2wt% phenoxyethanol, 0.5wt% glycerol, and the balance water.

[0047] Test Example 1 - Mouse Experiment A total of 130 C57BL / 6J male mice weighing approximately 18-22g were selected and, after 7 days of adaptive feeding, randomly divided into a blank group (10 mice) and a modeling group (120 mice). The modeling group received a subcutaneous injection of 5 mg / kg / d of testosterone propionate solution for 35 days to establish a seborrheic alopecia mouse model, and all mice successfully developed the model. The blank group received a subcutaneous injection of an equal volume of saline.

[0048] The modeling group was randomly divided into 12 groups, with 10 mice in each group, namely the model group, Example 1-4 and Comparative Example 1-7 groups. Hair depilation treatment was performed on an approximately 2 cm × 2 cm area on the back of all mice. The depilatory areas of the Example 1-4 and Comparative Example 1-7 groups were administered 2 g / mouse of the compositions prepared in Examples 1-4 and Comparative Example 1-7, respectively (specifically, the prepared compositions were dissolved in a small amount of physiological saline and applied to the depilatory areas using a cotton swab). The model group and the blank group were smeared with an equal amount of physiological saline for 22 consecutive days. The 10 longest hairs in the depilatory area on the back were measured to obtain the length of the newly grown hair. All the hair in the depilatory area was taken and electronically weighed to obtain the weight of the newly grown hair. The results are shown in Table 1.

[0049] Table 1

[0050] As shown in Table 1, compared to the model group, the mice in groups 1-4 treated with the corresponding compositions showed significantly increased hair length and weight after treatment. In particular, the composition of Example 4 achieved similar hair length and weight to those in the blank group, demonstrating that the composition of Example 4 effectively promotes hair growth. The data from Comparative Examples 1-7 demonstrate that the composition of Example 4 is essential, with each ingredient synergistically enhancing its effectiveness.

[0051] Test Example 2-Clinical Trial A study was conducted on 120 volunteers experiencing hair loss, with daily hair loss exceeding 200 strands. They were randomly divided into 12 groups: a control group, groups using Examples 1-4, and groups using Comparative Examples 1-7. Groups using Examples 1-4 and Comparative Examples 1-7 used the products prepared in the corresponding examples, while the control group used an equal amount of normal saline. The corresponding products were evenly applied at 7:00 PM each day. Hair loss from each group was collected on days 0, 20, and 45, and the averaged results are shown in Table 2.

[0052] Table 2

[0053] As can be seen from Table 2, compared with comparative examples 1-7, the products prepared by application examples 1-3 of the present invention have better anti-hair loss effects.

[0054] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A composition for preventing hair loss and strengthening hair, characterized in that: The raw materials include, by weight: 10-15 parts of ageratum leaf extract, 5-10 parts of lactobacillus / acerola cherry fermentation product, 10-15 parts of pomegranate bark / fruit extract and 6-10 parts of panax japonicus root extract.

2. A composition for preventing hair loss and strengthening according to claim 1, characterized in that: It also includes 4-6 parts of Rosa Damascena flower extract and 4-6 parts of Daffodil flower extract.

3. A composition for preventing hair loss and strengthening according to claim 2, characterized in that: The raw materials include, by weight: 10-15 parts of ageratum leaf extract, 5-10 parts of lactobacillus / acerola cherry fermentation product, 10-15 parts of pomegranate bark / fruit extract and 6-10 parts of panax japonicus root extract, 4-6 parts of rosa damascena flower extract, and 4-6 parts of daffodil flower extract.

4. A composition for preventing hair loss and strengthening hair according to claim 3, characterized in that: The preparation method of the ageratum leaf extract comprises: (1) Repeatedly freeze-thaw fresh Ageratum leaves and crush them to obtain the material; (2) treating the material with citric acid, performing hot-press distillation, collecting the distillate, and concentrating it to a solid content of 6-8 mg / mL to obtain an Ageratum leaf extract; In step (1), the freeze-thaw cycle is performed 2-3 times, the freezing temperature is -20 to -10°C, and the freezing time is 1 to 2 hours; In step (2), the material-liquid ratio of the material to citric acid is 1:5-8 g / mL; the concentration of the citric acid is 5-8 wt%; In step (2), the temperature of the hot-pressing distillation is 80-90° C., the time is 20-40 min, and the pressure is 0.11-0.13 MPa.

5. A composition for preventing hair loss and strengthening hair according to claim 3, characterized in that: The preparation method of the pomegranate bark / fruit extract comprises: (1) Crush fresh pomegranate bark / fruit, add it to complex enzyme solution 1, adjust the pH value to 6.0-6.5, and perform enzymolysis at 35-45°C for 40-60 minutes to obtain enzymatic hydrolyzate and residue; (2) adding the residue to the composite enzyme solution 2, adjusting the pH value to 7.5-8.0, performing enzymolysis at 50-60°C for 1-2 hours, collecting the enzymatic hydrolysate, combining the two enzymatic hydrolysates, concentrating under reduced pressure, and freeze-drying the obtained product to obtain a pomegranate bark / fruit extract; In step (1), the mass ratio of the pomegranate bark / fruit to the complex enzyme solution 1 is 1:10-20; the complex enzyme solution 1 comprises pectinase and desaccharidase in a mass ratio of 1:1-3, the enzyme activity of the pectinase is 2500-3500 U / mL, and the enzyme activity of the desaccharidase is 2000-3000 U / mL; In step (2), the mass ratio of the residue to the complex enzyme solution 2 is 1:10-15; the complex enzyme solution 2 comprises cellulase and amylase in a mass ratio of 1:0.8-1.8, the enzymatic activity of the cellulase is 2000-2500 U / mL, and the enzymatic activity of the amylase is 3000-3500 U / mL.

6. A composition for preventing hair loss and strengthening hair according to claim 3, characterized in that: The Panax japonicus root extract is Panax japonicus root ethanol extract and / or Panax japonicus root ethyl acetate extract; The ethanol extract of Panax japonicus root is prepared by mixing Panax japonicus root and ethanol at a material-liquid ratio of 1:10-20 g / mL, extracting at 60-70° C. for 1-3 hours, and concentrating under reduced pressure to obtain the ethanol extract of Panax japonicus root; The ethyl acetate extract of Panax japonicus root is prepared by mixing Panax japonicus root and ethyl acetate at a material-liquid ratio of 1:8-12 g / mL, extracting at 50-60° C. for 1-2 hours, and concentrating under reduced pressure to obtain the ethyl acetate extract of Panax japonicus root.

7. A composition for preventing hair loss and strengthening hair according to claim 3, characterized in that: The preparation method of the Rosa damascena flower extract comprises: (1) Crush the Rosa damascena flowers, add lactic acid bacteria, control the temperature at 25-30°C, and ferment in a sealed container for 5-7 hours; (2) adjusting the temperature to 33-36°C, adding yeast, and fermenting for 3-5 hours in a sealed container to obtain a fermentation product, which was then dried to obtain a Rosa damascena flower extract; In step (1), the lactic acid bacteria is at least one of Streptococcus thermophilus, Lactobacillus rhamnosus, Lactobacillus bulgaricus or Lactobacillus delbrueckii subspecies bulgaricus, and the amount added is 3%-5% of the weight of the Rosa damascena flower, and the number of viable bacteria is 1×10 7 CFU / mL; In step (2), the yeast is added in an amount of 6%-8% of the weight of the Rosa damascena flower, and the number of viable bacteria is 1×10 8 CFU / mL.

8. The composition for preventing hair loss and strengthening hair according to claim 3, wherein: The preparation method of the daffodil flower extract comprises: crushing the daffodil flower, placing the daffodil flower in a supercritical CO2 extraction device, extracting the daffodil flower at 20-30 MPa and 40-50° C. for 20-30 min, and concentrating under reduced pressure to obtain the daffodil flower extract.

9. A scalp preparation characterized by: The invention comprises the composition for preventing hair loss and strengthening hair according to any one of claims 1 to 8, and acceptable auxiliary materials.

10. The scalp preparation according to claim 9, wherein The concentration of the composition for preventing hair loss and strengthening hair is 5-10wt%; The scalp preparation includes shampoo or scalp essence.

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