Heparin sodium product sampling device

Abstract

The invention provides a heparin sodium product sampling device, and relates to the technical field of detection sampling devices, the heparin sodium product sampling device comprises a sampling barrel, a sampling nozzle, a piston and a drawing rod, the sampling nozzle is communicated with one end of the sampling barrel, the piston is slidably mounted in the sampling barrel, and one end of the drawing rod is fixedly connected with the piston; a plugging plate is fixedly installed in the sampling nozzle, a through hole is formed in the plugging plate in a penetrating mode, and the sampling nozzle is further provided with two plugging blocks. According to the heparin sodium product sampling device provided by the invention, the sampling barrel, the sampling nozzle, the piston, the drawing rod, the plugging plate, the two plugging blocks, the elastic reset structure and the adjusting structure are arranged, and an adjustable one-way valve structure is arranged in the sampling nozzle, so that when a sample is sampled or squeezed out, the position of the two plugging plates is adjusted; therefore, the sample is ensured to enter and flow out at the corresponding stage, the situation that the sample flows out of the sampling barrel in the storage or transfer process can be reduced, waste and pollution are reduced, and the accuracy of a detection result is ensured.

Description

Technical Field

[0001] The present invention relates to the technical field of detection sampling devices, in particular to a heparin sodium product sampling device. Background Art

[0002] Heparin sodium is an anticoagulant that prevents platelet aggregation and destruction, inhibits the conversion of fibrinogen to fibrin monomers, inhibits the formation of thrombin and counteracts existing thrombin, and prevents the conversion of prothrombin to thrombin and counteracts thrombin. It can delay or prevent blood coagulation both in vitro and in vivo, making it a crucial anticoagulant in the medical field.

[0003] Sodium heparin has a wide range of applications in the medical field, mainly including: clinical anticoagulation: sodium heparin is mostly used for the collection and anticoagulation of blood specimens in clinical biochemistry and emergency biochemistry examinations, and is also suitable for the collection and anticoagulation of blood specimens for some hemorheology projects; prevention and treatment of thrombosis: sodium heparin is clinically used to prevent and treat thrombosis, other thromboembolic diseases, such as myocardial infarction, thrombophlebitis, pulmonary embolism, etc., as well as disseminated intravascular coagulation caused by various reasons; surgical anticoagulation: sodium heparin can also be used in operations such as hemodialysis, extracorporeal circulation catheterization and microvascular surgery, as well as the anticoagulation treatment of certain blood specimens and instruments; therefore, accurate determination of the purity and content of sodium heparin is crucial to ensuring patient safety and efficacy, and its products need to be sampled and tested.

[0004] When sampling sodium heparin products, a pull-out sampling tube (syringe structure) is usually used to extract the sodium heparin product. However, in actual use, this type of sampling tube has no sealing structure at the sampling port, which may cause the sodium heparin product in the sampling tube to flow out, causing waste and pollution. Summary of the Invention

[0005] Based on the technical problems existing in the background technology, the present invention proposes a heparin sodium product sampling device.

[0006] The present invention provides a heparin sodium product sampling device, comprising a sampling barrel, a sampling nozzle, a piston, and a pull rod. The sampling nozzle is connected to one end of the sampling barrel, the piston is slidably installed in the sampling barrel, and one end of the pull rod is fixedly connected to the piston. A blocking plate is fixedly installed in the sampling nozzle, and a perforation is formed on the blocking plate. The sampling nozzle is also provided with two blocking blocks, and there is a gap between the two blocking blocks. The two blocking blocks are respectively located on both sides of the blocking plate. The diameter of the blocking block is smaller than the inner diameter of the sampling nozzle. The blocking block can block the perforation on the blocking plate. The sampling nozzle is provided with an elastic reset structure and an adjustment structure. The adjustment structure is used to adjust one of the two blocking blocks to abut against the blocking plate and block the perforation on the blocking plate; When the blocking block resting on the blocking plate is acted upon by an external force and moves away from the blocking plate, the elastic reset structure can drive the blocking block to reset and rest against the blocking plate.

[0007] Preferably, the two blocking blocks are fixedly connected to a connecting rod, the connecting rod passes through the through hole on the blocking plate, and the diameter of the connecting rod is smaller than the diameter of the through hole on the blocking plate.

[0008] Preferably, the elastic reset structure comprises a polygonal tube, a slider and an elastic component; a limiting slot is provided in the polygonal tube, the slider is slidably installed in the limiting slot, and one end of the connecting rod slides through the end of the polygonal tube and extends into the limiting slot to be fixedly connected to the slider; The elastic component is used to drive the slider to slide and reset in the limiting sliding groove.

[0009] Preferably, the elastic component includes a No. 1 spring and a No. 2 spring; the No. 1 spring and the No. 2 spring are both located in the limiting sliding groove, and the No. 1 spring and the No. 2 spring are respectively located on both sides of the slider.

[0010] Preferably, the adjustment structure includes a fixed cylinder, a rotating internal threaded cylinder, a threaded block and an adjustment assembly; the fixed cylinder is fixedly installed in the sampling nozzle, the diameter of the fixed cylinder is smaller than the inner diameter of the sampling nozzle, a working groove is provided in the fixed cylinder, the rotating internal threaded cylinder is rotatably installed in the working groove, the threaded block is located in the rotating internal threaded cylinder, the threaded block is threadedly matched with the rotating internal threaded cylinder, and one end of the polygonal cylinder passes through the fixed cylinder and extends into the working groove and is fixedly connected to the threaded block.

[0011] Preferably, the adjustment assembly includes a gear ring, an end face gear, an adjustment rod and an adjustment disk; the gear ring is sleeved on the outer circumference of the rotating internal threaded cylinder, the end face gear is rotatably installed in the fixed cylinder, and the end face gear is meshed with the gear ring, one end of the adjustment rod passes through the sampling nozzle, the fixed cylinder and the end face gear in sequence and is fixedly connected, and the adjustment disk is fixedly connected to the end of the adjustment rod away from the end face gear.

[0012] Preferably, the cross-section of the polygonal tube is a regular polygon.

[0013] The heparin sodium product sampling device proposed in the present invention has the following beneficial effects: by arranging a sampling barrel, a sampling nozzle, a piston, a pull rod, a sealing plate, two sealing blocks, an elastic reset structure and an adjustment structure, an adjustable one-way valve structure is arranged in the sampling nozzle, so that when sampling or squeezing a sample, by adjusting the positions of the two sealing plates, the entry and outflow of the sample are ensured at the corresponding stages, and the outflow of the sample from the sampling barrel during storage or transportation is also reduced, thereby reducing waste and pollution and ensuring the accuracy of the test results. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic diagram of the overall structure of a heparin sodium product sampling device proposed in the present invention.

[0015] Figure 2 This is a cross-sectional view of a heparin sodium product sampling device proposed by the present invention.

[0016] Figure 3 This is a diagram showing the positional relationship between two blocking blocks and a blocking plate when collecting samples in a heparin sodium product sampling device proposed by the present invention.

[0017] Figure 4 This is a structural schematic diagram of two blocking blocks, a connecting rod, a polygonal cylinder and a threaded block in a heparin sodium product sampling device proposed by the present invention.

[0018] Figure 5 The figure is a cross-sectional view of a fixed cylinder and a rotating internally threaded cylinder in a heparin sodium product sampling device proposed by the present invention.

[0019] Figure 6 This is a diagram showing the positional relationship between two blocking blocks and a blocking plate when extruding a sample in a heparin sodium product sampling device proposed by the present invention.

[0020] In the figure: 1. Sampling cylinder; 2. Sampling nozzle; 3. Piston; 4. Pull-out rod; 5. Sealing plate; 6. Sealing block; 7. Connecting rod; 8. Polygonal cylinder; 9. Slider; 10. Spring No. 1; 11. Spring No. 2; 12. Fixed cylinder; 13. Rotating internal thread cylinder; 14. Threaded block; 15. Gear ring; 16. End gear; 17. Adjusting rod; 18. Adjusting disk. DETAILED DESCRIPTION

[0021] Reference Figures 1-6 The present invention proposes a heparin sodium product sampling device, including a sampling cylinder 1, a sampling nozzle 2, a piston 3 and a pulling rod 4. The sampling nozzle 2 is connected to one end of the sampling cylinder 1, the piston 3 is slidably installed in the sampling cylinder 1, and one end of the pulling rod 4 is fixedly connected to the piston 3; the working principle of the sampling cylinder 1, the sampling nozzle 2, the piston 3 and the pulling rod 4 is similar to that of a syringe. The staff grasps the sampling cylinder 1 with one hand and grasps the pulling rod 4 with the other hand. The piston 3 is driven to slide in the sampling cylinder 1 through the pulling rod 4, thereby changing the air pressure in the sampling cylinder 1, so that the heparin sodium product enters the sampling cylinder 1 from the sampling nozzle 2.

[0022] like Figure 2 、 Figure 3 、 Figure 4 and Figure 6As shown in the figure, a sealing plate 5 is fixedly installed in the sampling nozzle 2. A perforation is opened through the sealing plate 5. The openings at both ends of the perforation are tapered openings. The sampling nozzle 2 is also provided with two sealing blocks 6. A rubber pad is set on the sealing block 6. There is a gap between the two sealing blocks 6. The two sealing blocks 6 are respectively located on both sides of the sealing plate 5. In actual use, the two sealing blocks 6 are respectively against the two sides of the sealing plate 5, thereby playing the role of a one-way valve in two directions in different states. The diameter of the sealing block 6 is smaller than the inner diameter of the sampling nozzle 2. The sealing block 6 can block the perforation on the sealing plate 5. The two blocking blocks 6 always have only One can contact the blocking plate 5, that is, only one of the two blocking blocks 6 can always play a role, and the two cannot play a blocking role at the same time. The sampling nozzle 2 is equipped with an elastic reset structure and an adjustment structure; the adjustment structure is used to adjust one of the two blocking blocks 6 to lean against the blocking plate 5 and block the perforation on the blocking plate 5; when the blocking block 6 leaning against the blocking plate 5 is acted upon by an external force to move away from the blocking plate 5, the elastic reset structure can drive the blocking block 6 to reset and lean against the blocking plate 5. In actual operation, for example, when sampling, the two blocking blocks 6 are adjusted by the adjustment structure as follows Figure 3 When the bottle is in the state shown in FIG, the upper blocking block 6 abuts against the blocking plate 5 and blocks the perforation on the blocking plate 5, so that the upper blocking block 6 cannot continue to fall. When the heparin sodium product is extracted, the air pressure in the sampling tube 1 becomes smaller, and the external air pressure squeezes the heparin sodium product into the sampling tube 1 through the sampling nozzle 2. At the same time, it pushes the blocking block 6 upward to open the perforation on the blocking plate 5, and when the sampling is completed, the upper blocking block 6 is driven downward to reset under the action of the elastic reset structure, and blocks the perforation on the blocking plate 5 to prevent the heparin sodium product in the sampling tube 1 from flowing out. When the heparin sodium product in the sampling tube 1 flows out from the sampling nozzle 2, the blocking block 6 cannot move downward, so that the heparin sodium product cannot flow out from the sampling nozzle 2. Even if the pulling rod 4 is accidentally touched and squeezed, the heparin sodium product cannot be squeezed out. When the heparin sodium product needs to be squeezed out, the two blocking blocks 6 are adjusted to the following positions by adjusting the structure. Figure 6 , that is, the lower blocking block 6 blocks the lower end opening of the perforation on the blocking plate 5, and the blocking block 6 cannot continue to rise. The external sodium heparin product cannot push the blocking block 6 to move into the sampling tube 1. The staff squeezes the pull rod 4 to make the piston 3 slide in the sampling tube 1, so that the sodium heparin product in the sampling tube 1 exerts a downward force on the blocking block 6 below, causing the blocking block 6 to move downward and open the perforation on the blocking plate 5, allowing the sodium heparin product in the sampling tube 1 to be squeezed out. At this time, the upper blocking block 6 cannot play a blocking role on the perforation, ensuring that the sodium heparin product is squeezed out.

[0023] like Figure 3 and Figure 4As shown in the figure, the two blocking blocks 6 are fixedly connected to a connecting rod 7, the axes of the two blocking blocks 6 and the connecting rod 7 coincide, the connecting rod 7 passes through the through-hole on the blocking plate 5, and the diameter of the connecting rod 7 is smaller than the diameter of the through-hole on the blocking plate 5, ensuring that a certain interval is maintained between the two blocking blocks 6, ensuring that the interval between the two blocking blocks 6 remains unchanged during switching, and ensuring that the two blocking blocks 6 can be adjusted at the same time during adjustment.

[0024] like Figure 3 、 Figure 4 and Figure 6 As shown in the figure, the elastic reset structure includes a polygonal cylinder 8, a slider 9 and an elastic component; a limited slide groove is provided in the polygonal cylinder 8, the axis of the limited slide groove coincides with the axis of the polygonal cylinder 8, and the slider 9 is slidably installed in the limited slide groove. In the normal state, the slider 9 is located in the middle position of the limited slide groove. When the slider 9 is subjected to external force, it can move to both ends of the limited slide groove. One end of the connecting rod 7 slides through the end of the polygonal cylinder 8 and extends into the limited slide groove and is fixedly connected to the slider 9. The elastic component is used to drive the slider 9 to the limit The slider 9 slides in the limiting groove and resets, and the elastic component includes a No. 1 spring 10 and a No. 2 spring 11; the No. 1 spring 10 and the No. 2 spring 11 are both located in the limiting groove, and the No. 1 spring 10 and the No. 2 spring 11 are respectively located on both sides of the slider 9. When the slider 9 slides in the limiting groove, the slider 9 will squeeze the No. 1 spring 10 or the No. 2 spring 11. When resetting, the slider 9 is driven by the rebound action of the squeezed spring to slide and reset in the limiting groove, so that the slider 9 returns to the middle position of the limiting groove.

[0025] like Figure 2 、 Figure 3 、 Figure 4 、 Figure 5 and Figure 6As shown in, the adjustment structure includes a fixed cylinder 12, a rotating internal threaded cylinder 13, a threaded block 14 and an adjustment component. The outer periphery of the fixed cylinder 12 is fixedly installed on the inner wall of the sampling nozzle 2 through a bracket. The axis of the fixed cylinder 12 coincides with the bearing of the sampling nozzle 2. The diameter of the fixed cylinder 12 is smaller than the inner diameter of the sampling nozzle 2. A working groove is provided in the fixed cylinder 12. The axis of the working groove coincides with the axis of the fixed cylinder 12. The rotating internal threaded cylinder 13 is rotatably installed in the working groove. The axis of the rotating internal threaded cylinder 13 also coincides with the axis of the fixed cylinder 12. The rotating internal threaded cylinder 13 cannot slide in the working groove. The inner ring wall of the rotating internal threaded cylinder 13 is provided with threads. The threaded block 14 is located at the rotating internal threaded cylinder 13 Inside, the threaded block 14 is threadedly matched with the rotating internal threaded cylinder 13, and one end of the polygonal cylinder 8 passes through the fixed cylinder 12 and extends into the working groove and is fixedly connected with the threaded block 14. When the rotating internal threaded cylinder 13 rotates, the threaded block 14 is threadedly matched with the rotating internal threaded cylinder 13. The cross-sectional view of the polygonal cylinder 8 is a regular hexagon, and the polygonal cylinder 8 cannot rotate with the fixed cylinder 12. Because the polygonal cylinder 8 cannot rotate, the threaded block 14 slides in the rotating internal threaded cylinder 13, thereby driving the polygonal cylinder 8 to move synchronously, and then the polygonal cylinder 8 drives the connecting rod 7 and the two blocking blocks 6 to move synchronously, thereby adjusting the positions of the two blocking blocks 6, so that the two blocking blocks 6 act as one-way valves in two directions.

[0026] like Figure 2 、 Figure 3 、 Figure 5 and Figure 6 As shown in , the adjustment assembly includes a gear ring 15, an end gear 16, an adjustment rod 17 and an adjustment disk 18; the gear ring 15 is sleeved on the outer periphery of the rotating internal threaded cylinder 13, the end gear 16 is rotatably installed in the fixed cylinder 12, and the end gear 16 is meshed with the gear ring 15, one end of the adjustment rod 17 sequentially passes through the sampling nozzle 2, the fixed cylinder 12 and the end gear 16 and is fixedly connected, and the adjustment disk 18 is fixedly connected to the end of the adjustment rod 17 away from the end gear 16. When adjusting the position of the two blocking blocks 6, the staff pinches the adjustment disk 18 and rotates the adjustment disk 18. The adjusting plate 18 drives the adjusting rod 17 and the end face gear 16 to rotate synchronously. When the end face gear 16 rotates, the end face gear 16 and the gear ring 15 are engaged, driving the gear ring 15 to rotate, and the gear ring 15 drives the rotating internal threaded barrel 13 to rotate synchronously. The rotating rotating internal threaded barrel 13 and the threaded block 14 are threadedly matched, so that the threaded block 14 slides in the rotating internal threaded barrel 13, thereby changing the position of the two blocking blocks 6, thereby playing the role of a one-way valve in different directions; for example, when sampling heparin sodium product, the positions of the two blocking blocks 6 and the blocking plate 5 are as follows Figure 3 When the sodium heparin product is squeezed outward, the positions of the two blocking blocks 6 and the blocking plate 5 are as shown in FIG. Figure 6 As shown in .

[0027] The sampling work of heparin sodium products is as follows: 1. Preparation Make sure the work area is clean and tidy, and prepare the necessary sampling tools and equipment, such as sampling tubes, label paper, etc.

[0028] Wear appropriate personal protective equipment, such as gloves, masks, and goggles, to prevent sample contamination or personal injury.

[0029] 2. Sampling steps Select samples: Select representative samples from the container storing heparin sodium (e.g. low molecular weight heparin sodium injection, dalteparin sodium, etc.).

[0030] Sampling tool cleaning: Before using sampling tools, ensure they are cleaned and sterilized to avoid cross contamination.

[0031] sampling: Use the sampling tube to draw an appropriate amount of heparin sodium solution from the container.

[0032] Label record: Attach a label to the sampling tube, indicating the name of the sample, sampling date, sampling personnel and other information; at the same time, record detailed sampling information such as sampling volume, sampling time, etc.

[0033] 3. Subsequent Processing Sample storage: Store the collected heparin sodium samples under appropriate conditions, such as refrigeration or protection from light, to prevent sample deterioration or degradation.

[0034] Sample analysis: Based on experimental requirements, the collected heparin sodium samples will be sent to the laboratory for analysis or testing.

[0035] IV. Precautions During the sampling process, avoid sample contamination or cross contamination.

[0036] Sampling tools and equipment should be properly cleaned and disinfected.

[0037] Samples should be stored under appropriate conditions to ensure their quality and stability.

[0038] During the sampling process, relevant safety operating procedures and laboratory rules and regulations must be followed.

[0039] Please note that the above steps may vary depending on the specific requirements of the laboratory and the storage conditions of heparin sodium; in actual operation, they should be adjusted and optimized according to specific circumstances.

[0040] The above description is only a preferred specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any technician familiar with the technical field, within the technical scope disclosed by the present invention, who makes equivalent replacements or changes based on the technical solution and inventive concept of the present invention, should be covered by the scope of protection of the present invention.

Claims

1. A heparin sodium product sampling device, characterized in that: It comprises a sampling barrel (1), a sampling nozzle (2), a piston (3) and a pulling rod (4), wherein the sampling nozzle (2) is connected to one end of the sampling barrel (1), the piston (3) is slidably installed in the sampling barrel (1), and one end of the pulling rod (4) is fixedly connected to the piston (3); A blocking plate (5) is fixedly installed in the sampling nozzle (2), and a through-hole is formed on the blocking plate (5). The sampling nozzle (2) is also provided with two blocking blocks (6), and there is a gap between the two blocking blocks (6). The two blocking blocks (6) are respectively located on both sides of the blocking plate (5). The diameter of the blocking block (6) is smaller than the inner diameter of the sampling nozzle (2). The blocking block (6) can block the through-hole on the blocking plate (5). The sampling nozzle (2) is provided with an elastic reset structure and an adjustment structure. The adjustment structure is used to adjust one of the two blocking blocks (6) to abut against the blocking plate (5) and block the perforation on the blocking plate (5); When the blocking block (6) abutting against the blocking plate (5) is acted upon by an external force and moves away from the blocking plate (5), the elastic reset structure can drive the blocking block (6) to reset and abut against the blocking plate (5).

2. A heparin sodium product sampling device according to claim 1, characterized in that: The two blocking blocks (6) are both fixedly connected to a connecting rod (7), the connecting rod (7) passing through the through hole on the blocking plate (5), and the diameter of the connecting rod (7) is smaller than the diameter of the through hole on the blocking plate (5).

3. A heparin sodium product sampling device according to claim 2, characterized in that: The elastic reset structure comprises a polygonal cylinder (8), a slider (9) and an elastic component; a limiting slide groove is provided in the polygonal cylinder (8), the slider (9) is slidably mounted in the limiting slide groove, and one end of the connecting rod (7) slides through the end of the polygonal cylinder (8) and extends into the limiting slide groove to be fixedly connected to the slider (9); The elastic component is used to drive the slider (9) to slide and reset in the limiting sliding groove.

4. A heparin sodium product sampling device according to claim 3, characterized in that: The elastic component includes a No. 1 spring (10) and a No. 2 spring (11); the No. 1 spring (10) and the No. 2 spring (11) are both located in the limiting sliding groove, and the No. 1 spring (10) and the No. 2 spring (11) are respectively located on both sides of the slider (9).

5. A heparin sodium product sampling device according to claim 6, characterized in that: The adjustment structure includes a fixed cylinder (12), a rotating internal threaded cylinder (13), a threaded block (14) and an adjustment component; the fixed cylinder (12) is fixedly installed in the sampling nozzle (2); the diameter of the fixed cylinder (12) is smaller than the inner diameter of the sampling nozzle (2); a working groove is provided in the fixed cylinder (12); the rotating internal threaded cylinder (13) is rotatably installed in the working groove; the threaded block (14) is located in the rotating internal threaded cylinder (13); the threaded block (14) is threadedly matched with the rotating internal threaded cylinder (13); one end of the polygonal cylinder (8) passes through the fixed cylinder (12) and extends into the working groove to be fixedly connected to the threaded block (14).

6. A heparin sodium product sampling device according to claim 7, characterized in that: The adjustment assembly includes a gear ring (15), an end face gear (16), an adjustment rod (17) and an adjustment disk (18); the gear ring (15) is sleeved on the outer periphery of the rotating internal thread cylinder (13), the end face gear (16) is rotatably installed in the fixed cylinder (12), and the end face gear (16) is meshed with the gear ring (15), one end of the adjustment rod (17) passes through the sampling nozzle (2), the fixed cylinder (12) and the end face gear (16) in sequence and is fixedly connected, and the adjustment disk (18) is fixedly connected to the end of the adjustment rod (17) away from the end face gear (16).

7. A heparin sodium product sampling device according to claim 1, characterized in that: The cross-section of the polygonal cylinder (8) is a regular polygon.

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