Medicinal and edible product for relaxing bowel and preparation method thereof

Abstract

The invention relates to the technical field of functional food, in particular to a medicinal and edible product for relaxing bowel and a preparation method, the medicinal and edible product comprises the following raw materials: 30-45 parts of an active composition, 5-15 parts of semen cassiae, 3-10 parts of folium mori, 2-10 parts of angelica sinensis, 5-8 parts of cistanche, 10-15 parts of pericarpium citri reticulatae, 10-30 parts of honey, 5-15 parts of fructo-oligosaccharide and 40-60 parts of deionized water; the specific preparation method comprises the following steps: adding the honey and the fructo-oligosaccharide into the deionized water, and uniformly mixing to obtain mixed syrup; the semen cassiae, the radix angelicae sinensis, the herba cistanche, the pericarpium citri reticulatae and the folium mori are washed, dried in the air and added into the mixed syrup, the active composition is added, and the medicinal and edible product is obtained after uniform stirring. According to the medicinal and edible product, the fructus cannabis zymolyte is used for lubricating and repairing, the fermented bunge cherry seeds and the probiotics are used for regulating intestinal motility and flora, and the semen cassiae, the folium mori and the like are matched for synergistic interaction, so that the effects of improving defecation in multiple dimensions and relaxing bowel are remarkable.

Description

Technical Field

[0001] The present application relates to the technical field of functional foods, and more specifically, to a medicinal and edible product for moistening the intestines and promoting bowel movements and a preparation method thereof. Background Art

[0002] Constipation is a common clinical syndrome caused by factors such as decreased colonic propulsion, increased resistance to colonic contents, insufficient pelvic floor muscle relaxation, or an inability to generate sufficient force during defecation. Currently, commonly used medications for constipation include osmotic laxatives and stimulant laxatives. However, while these Western medications offer laxative benefits, they often carry adverse effects. For example, osmotic laxatives can cause dose-dependent abdominal cramping and bloating, while overdose can lead to electrolyte imbalances. Long-term use of stimulant laxatives can cause intestinal nerve damage and melanosis coli, posing safety risks. In contrast, medicinal and edible products are gaining increasing attention due to their natural, safe, and minimal side effects. Developing products with laxative properties using dual-purpose medicinal and edible ingredients can leverage the benefits of Traditional Chinese Medicine (TCM) for health conditioning while also meeting people's desire for natural, healthy foods. Therefore, developing a laxative product with improved efficacy, safety, and consistent with the concept of medicinal and edible laxatives, and its preparation method, is of great practical significance and holds promising market potential, potentially meeting the needs of constipation sufferers and those concerned about their health. Summary of the Invention

[0003] In order to solve the technical problems mentioned in the background technology, the present application provides a medicinal and edible product for moistening the intestines and promoting bowel movements and a preparation method thereof.

[0004] The present application provides a medicinal and edible product for moistening the intestines and relieving constipation, which adopts the following technical solution: A medicinal and edible product for moistening the intestines and promoting bowel movements comprises the following raw materials in parts by weight: 30-45 parts of an active composition, 5-15 parts of cassia seeds, 3-10 parts of mulberry leaves, 2-10 parts of angelica sinensis, 5-8 parts of cistanche deserticola, 10-15 parts of tangerine peel, 10-30 parts of honey, 5-15 parts of oligofructose, and 40-60 parts of deionized water.

[0005] Preferably, the preparation of the active composition comprises the following preparation steps: Step S1, after washing the hemp seed, baking it at 60-80° C. for 2-3 hours, crushing and sieving to obtain hemp seed powder; adding deionized water to the hemp seed powder, mixing uniformly to obtain a slurry; adjusting the pH value of the slurry to 7.0-7.5, adding a complex enzyme preparation, enzymolyzing it at 50-55° C. for 3-5 hours, filtering, and collecting the filtrate to obtain a hemp seed enzymolysis solution; Step S2: Wash the Prunus mume seeds and the citron, crush and sieve to obtain a mixed powder, add deionized water to the mixed powder, and mix evenly to obtain a mixed solution; heat the mixed solution to 90-100° C., maintain for 10-15 minutes, cool naturally to 30-37° C., inoculate with composite probiotics, perform anaerobically fermentation for 2-3 days, and filter to obtain a composite fermentation liquid; Step S3: mixing the hemp seed enzymatic hydrolysate and the composite fermentation liquid, adding a protective agent, mixing evenly, and freeze-drying to obtain an active composition.

[0006] Preferably, the mass ratio of hemp seed, Prunus mume seed and citron is 5-15:3-10:1-4.

[0007] Preferably, the mass ratio of the hemp seed powder to deionized water is 25-40:100-120.

[0008] Preferably, the complex enzyme preparation is composed of flavor protease, bromelain and papain in a mass ratio of 5-8:3-5:1-2.

[0009] Preferably, the added amount of the complex enzyme preparation is 0.5-2.0% of the mass of the hemp seed powder.

[0010] Preferably, the mass ratio of the mixed powder to deionized water is 30-50:80-100.

[0011] Preferably, the inoculation amount of the composite probiotics is 3-5% of the mass of the mixed solution.

[0012] Preferably, the anaerobic fermentation temperature of the composite probiotics is 35-37° C., and the fermentation pH is 5.5-7.0.

[0013] Preferably, the composite probiotics are composed of Bifidobacterium bifidum, Lactobacillus rhamnosus and Lactobacillus reuteri in a mass ratio of 10-12:3-8:1-3.

[0014] Preferably, the protective agent is one or more of trehalose, mannitol, maltodextrin, glycerol, polyvinyl pyrrolidone, and hydroxypropyl methylcellulose.

[0015] Preferably, the added amount of the protective agent is 10-20% of the total mass of the hemp seed hydrolyzate and the composite fermentation liquid.

[0016] The present application also provides a method for preparing a medicinal and edible product for moistening the intestines and relieving constipation, which adopts the following technical solution: A method for preparing a medicinal and edible product for moistening the intestines and promoting bowel movements, comprising the following steps: Honey and oligofructose are added to deionized water and mixed evenly to obtain a mixed syrup; Cassia seed, mulberry leaf, angelica, Cistanche deserticola and dried tangerine peel are washed and dried, crushed and sieved, and added to the mixed syrup and stirred evenly; then the active composition is added and stirred evenly to obtain a medicinal and edible product for moistening the intestines and promoting bowel movements.

[0017] In summary, this application has the following beneficial effects: This application uses hemp seeds rich in oil and protein for targeted enzymatic hydrolysis. Flavor protease, papain and bromelain work together to efficiently decompose the protein and dietary fiber in hemp seeds and efficiently release fatty acids, oligosaccharides and other intestinal moisturizing ingredients. If the proportion of papain is too high, excessive protein decomposition will produce bitter peptides. At the same time, insufficient flavor protease will affect the production efficiency of small molecule peptides and reduce the physiological activity of the enzymatic hydrolysate. Enzymatic hydrolysis avoids the oxidation and rancidity of oils caused by fermentation. Prunus mume seeds and bergamot are fermented by composite probiotics. Prunus mume seeds contain amygdalin and bergamot contains flavonoid glycosides. Fermentation can Glycosides are converted into active aglycones to enhance bioavailability. Bifidobacterium bifidum, the primary fermenting bacteria, produces short-chain fatty acids, promoting bowel movement and laxative effects. Lactobacillus rhamnosus secretes antimicrobial peptides to inhibit harmful bacteria, and Lactobacillus reuteri produces reuterin, strengthening the intestinal barrier function. The three bacterial communities work together to enhance nourishment to the intestinal mucosa, significantly improving bowel moisturizing effects. Hemp seed hydrolysate provides small molecule peptides and fatty acids, while the fermentation broth provides a variety of probiotic metabolites. The synergistic combination of these two precisely targets and repairs the intestinal mucosa, while also stimulating intestinal peristalsis and enhancing intestinal motility. This two-pronged approach, from repair to activation, delivers excellent bowel moisturizing and laxative effects, effectively treating constipation. DETAILED DESCRIPTION

[0018] The present application is further described in detail below with reference to the embodiments.

[0019] Bifidobacterium bifidum (item number: B86053), Lactobacillus rhamnosus (item number: B70030), and Lactobacillus reuteri (item number: B336073) used in the examples and comparative examples of the present application were all purchased from Ningbo Mingzhou Biotechnology Co., Ltd.; flavor protease (enzyme activity: 50,000 / g), bromelain (enzyme activity: 50,000 / g), and papain (enzyme activity: 100,000 / g) were all purchased from Chengdu Wanxiang Hongrun Biotechnology Co., Ltd.

[0020] Examples 1-3 provide a medicinal and edible product for moistening the intestines and promoting bowel movements and a preparation method thereof. Example

[0021] A medicinal and edible product for moistening the intestines and promoting bowel movements comprises the following raw materials in parts by weight: 30 parts of an active ingredient, 5 parts of cassia seeds, 3 parts of mulberry leaves, 2 parts of angelica sinensis, 5 parts of cistanche deserticola, 10 parts of tangerine peel, 10 parts of honey, 5 parts of oligofructose, and 40 parts of deionized water.

[0022] The preparation of the active composition comprises the following steps: Step S1, after washing the hemp seed, baking it at 60° C. for 2 hours, and crushing it through a 100-mesh sieve to obtain hemp seed powder; adding deionized water to the hemp seed powder, stirring it at a stirring speed of 200 rpm for 10 minutes, and mixing it evenly to obtain a slurry; adjusting the pH value of the slurry to 7.0, adding a composite enzyme preparation, wherein the amount of the composite enzyme preparation added is 0.5% of the mass of the hemp seed powder, enzymolyzing it at 50° C. for 3 hours, filtering, and collecting the filtrate to obtain a hemp seed enzymatic hydrolyzate, wherein the mass ratio of the hemp seed powder to the deionized water is 25:100, and the composite enzyme preparation is composed of flavor protease, bromelain, and papain in a mass ratio of 5:3:1; Step S2, washing the Prunus mume and the citron, crushing them through a 100-mesh sieve to obtain a mixed powder, adding deionized water to the mixed powder, and mixing them evenly to obtain a mixed solution; heating the mixed solution to 90° C., holding for 10 minutes, and naturally cooling it to 30° C., inoculating the composite probiotics in an amount of 3% of the mass of the mixed solution, and performing anaerobically fermentation for 2 days at a temperature of 35° C. and a fermentation pH of 5.5. Filtering to obtain a composite fermentation liquid, wherein the mass ratio of the mixed powder to deionized water is 30:80, the composite probiotics are composed of Bifidobacterium bifidum, Lactobacillus rhamnosus, and Lactobacillus reuteri in a mass ratio of 10:3:1, and the mass ratio of hemp seed, Prunus mume, and citron is 5:3:1; Step S3: mixing the hemp seed enzymatic hydrolysate and the composite fermentation liquor, adding maltodextrin, mixing evenly, and freeze-drying to obtain an active composition, wherein the amount of maltodextrin added is 10% of the total mass of the hemp seed enzymatic hydrolysate and the composite fermentation liquor.

[0023] A method for preparing a medicinal and edible product for moistening the intestines and promoting bowel movements, comprising the following steps: Honey and oligofructose are added to deionized water, stirred at a speed of 300 rpm for 10 minutes, and mixed evenly to obtain a mixed syrup; Cassia seed, mulberry leaf, angelica, Cistanche deserticola and tangerine peel are washed and dried, crushed through a 200-mesh sieve, added to the mixed syrup, stirred at a speed of 200 rpm for 10 minutes, and mixed evenly; the active composition is added, stirred at a speed of 100 rpm for 5 minutes, and mixed evenly to obtain a medicinal and edible product for moistening the intestines and promoting bowel movements. Example

[0024] A medicinal and edible product for moistening the intestines and promoting bowel movements comprises the following raw materials in parts by weight: 35 parts of an active ingredient, 10 parts of cassia seeds, 7 parts of mulberry leaves, 6 parts of angelica sinensis, 7 parts of cistanche deserticola, 12 parts of tangerine peel, 20 parts of honey, 10 parts of oligofructose, and 50 parts of deionized water.

[0025] The preparation of the active composition comprises the following steps: Step S1, after washing the hemp seed, baking it at 70° C. for 2.5 hours, and crushing it through a 150-mesh sieve to obtain hemp seed powder; adding deionized water to the hemp seed powder, stirring it at a stirring speed of 300 rpm for 15 minutes, and mixing it evenly to obtain a slurry; adjusting the pH value of the slurry to 7.2, adding a composite enzyme preparation, wherein the amount of the composite enzyme preparation added is 1% of the mass of the hemp seed powder, enzymolyzing it at 52° C. for 4 hours, filtering, and collecting the filtrate to obtain a hemp seed enzymatic hydrolyzate, wherein the mass ratio of the hemp seed powder to the deionized water is 32:110, and the composite enzyme preparation is composed of flavor protease, bromelain, and papain in a mass ratio of 6:4:1.5; Step S2, washing the Prunus mume and the citron, crushing them through a 150-mesh sieve to obtain a mixed powder, adding deionized water to the mixed powder, and mixing them evenly to obtain a mixed solution; heating the mixed solution to 95° C., holding for 12 minutes, and naturally cooling it to 35° C., inoculating the composite probiotics in an amount of 4% of the mass of the mixed solution, and performing anaerobically fermentation for 2.5 days at a temperature of 36° C. and a fermentation pH of 6.2. Filtering to obtain a composite fermentation liquid, wherein the mass ratio of the mixed powder to deionized water is 40:90, the composite probiotics are composed of Bifidobacterium bifidum, Lactobacillus rhamnosus, and Lactobacillus reuteri in a mass ratio of 11:6:2, and the mass ratio of hemp seed, Prunus mume, and citron is 10:6:3; Step S3: mixing the hemp seed enzymatic hydrolysate and the composite fermentation liquor, adding maltodextrin, mixing evenly, and freeze-drying to obtain an active composition, wherein the amount of maltodextrin added is 15% of the total mass of the hemp seed enzymatic hydrolysate and the composite fermentation liquor.

[0026] A method for preparing a medicinal and edible product for moistening the intestines and promoting bowel movements, comprising the following steps: Honey and oligofructose are added to deionized water, stirred at a speed of 400 rpm, and mixed for 15 minutes. After mixing evenly, a mixed syrup is obtained; Cassia seed, mulberry leaf, angelica, Cistanche deserticola and tangerine peel are washed and dried, crushed through a 300-mesh sieve, added to the mixed syrup, stirred at a speed of 300 rpm, and mixed for 20 minutes. After stirring evenly, the active composition is added, stirred at a speed of 150 rpm, and mixed for 12 minutes. After stirring evenly, a medicinal and edible product for moistening the intestine and promoting bowel movements is obtained. Example

[0027] A medicinal and edible product for moistening the intestines and promoting bowel movements comprises the following raw materials in parts by weight: 45 parts of an active ingredient, 15 parts of cassia seeds, 10 parts of mulberry leaves, 10 parts of angelica sinensis, 8 parts of cistanches, 15 parts of dried tangerine peels, 30 parts of honey, 15 parts of oligofructose, and 60 parts of deionized water.

[0028] The preparation of the active composition comprises the following steps: Step S1, after washing the hemp seed, baking it at 80° C. for 3 hours, and crushing it through a 200-mesh sieve to obtain hemp seed powder; adding deionized water to the hemp seed powder, stirring it at a stirring speed of 400 rpm for 20 minutes, mixing it evenly, and obtaining a slurry; adjusting the pH value of the slurry to 7.5, adding a composite enzyme preparation, wherein the amount of the composite enzyme preparation added is 2.0% of the mass of the hemp seed powder, enzymolyzing it at 55° C. for 5 hours, filtering, and collecting the filtrate to obtain a hemp seed enzymatic hydrolyzate, wherein the mass ratio of the hemp seed powder to the deionized water is 40:120, and the composite enzyme preparation is composed of flavor protease, bromelain, and papain in a mass ratio of 8:5:2; Step S2, washing the Prunus mume and the citron, crushing them through a 200-mesh sieve to obtain a mixed powder, adding deionized water to the mixed powder, and mixing them evenly to obtain a mixed solution; heating the mixed solution to 100° C., holding for 15 minutes, and naturally cooling to 37° C., inoculating the composite probiotics in an amount of 5% of the mass of the mixed solution, and performing anaerobically fermentation for 3 days at a temperature of 37° C. and a fermentation pH of 7.0. Filtering to obtain a composite fermentation liquid, wherein the mass ratio of the mixed powder to deionized water is 50:100, the composite probiotics are composed of Bifidobacterium bifidum, Lactobacillus rhamnosus, and Lactobacillus reuteri in a mass ratio of 12:8:3, and the mass ratio of hemp seed, Prunus mume, and citron is 15:10:4; Step S3: mixing the hemp seed enzymatic hydrolysate and the composite fermentation liquor, adding maltodextrin, mixing evenly, and freeze-drying to obtain an active composition, wherein the amount of maltodextrin added is 20% of the total mass of the hemp seed enzymatic hydrolysate and the composite fermentation liquor.

[0029] A method for preparing a medicinal and edible product for moistening the intestines and promoting bowel movements, comprising the following steps: Honey and oligofructose are added to deionized water, stirred at a speed of 500 rpm, and mixed for 20 minutes. After mixing evenly, a mixed syrup is obtained; Cassia seed, mulberry leaf, angelica, Cistanche deserticola and tangerine peel are washed and dried, crushed through a 400-mesh sieve, added to the mixed syrup, stirred at a speed of 400 rpm, and mixed for 30 minutes. After stirring evenly, the active composition is added, stirred at a speed of 200 rpm, and mixed for 20 minutes. After stirring evenly, a medicinal and edible product for moistening the intestine and promoting bowel movements is obtained.

[0030] Comparative Example 1 A medicinal and edible product for moistening the intestines and promoting bowel movements comprises the following raw materials in parts by weight: 30 parts of an active ingredient, 5 parts of cassia seeds, 3 parts of mulberry leaves, 2 parts of angelica sinensis, 5 parts of cistanche deserticola, 10 parts of tangerine peel, 10 parts of honey, 5 parts of oligofructose, and 40 parts of deionized water.

[0031] The preparation of the active composition comprises the following steps: Step S1, after washing the hemp seed, baking it at 60° C. for 2 hours, and crushing it through a 100-mesh sieve to obtain hemp seed powder; adding deionized water to the hemp seed powder, stirring it at a stirring speed of 200 rpm for 10 minutes, mixing it evenly, and obtaining a slurry; adjusting the pH value of the slurry to 7.0, adding a composite enzyme preparation, wherein the amount of the composite enzyme preparation added is 0.5% of the mass of the hemp seed powder, enzymolyzing it at 50° C. for 3 hours, filtering, and collecting the filtrate to obtain a hemp seed enzymatic hydrolyzate, wherein the mass ratio of the hemp seed powder to the deionized water is 25:100, and the composite enzyme preparation is composed of flavor protease, bromelain, and papain in a mass ratio of 1:3:5; Step S2, washing the Prunus mume and the citron, crushing them through a 100-mesh sieve to obtain a mixed powder, adding deionized water to the mixed powder, and mixing them evenly to obtain a mixed solution; heating the mixed solution to 90° C., holding for 10 minutes, and naturally cooling it to 30° C., inoculating the composite probiotics in an amount of 3% of the mass of the mixed solution, and performing anaerobically fermentation for 2 days at a temperature of 35° C. and a fermentation pH of 5.5. Filtering to obtain a composite fermentation liquid, wherein the mass ratio of the mixed powder to deionized water is 30:80, the composite probiotics are composed of Bifidobacterium bifidum, Lactobacillus rhamnosus, and Lactobacillus reuteri in a mass ratio of 10:3:1, and the mass ratio of hemp seed, Prunus mume, and citron is 5:3:1; Step S3: mixing the hemp seed enzymatic hydrolysate and the composite fermentation liquor, adding maltodextrin, mixing evenly, and freeze-drying to obtain an active composition, wherein the amount of maltodextrin added is 10% of the total mass of the hemp seed enzymatic hydrolysate and the composite fermentation liquor.

[0032] A method for preparing a medicinal and edible product for moistening the intestines and promoting bowel movements, comprising the following steps: Honey and oligofructose are added to deionized water, stirred at a speed of 300 rpm for 10 minutes, and mixed evenly to obtain a mixed syrup; Cassia seed, mulberry leaf, angelica, Cistanche deserticola and tangerine peel are washed and dried, crushed through a 200-mesh sieve, added to the mixed syrup, stirred at a speed of 200 rpm for 10 minutes, and mixed evenly; the active composition is added, stirred at a speed of 100 rpm for 5 minutes, and mixed evenly to obtain a medicinal and edible product for moistening the intestines and promoting bowel movements.

[0033] Comparative Example 2 A medicinal and edible product for moistening the intestines and promoting bowel movements comprises the following raw materials in parts by weight: 30 parts of an active ingredient, 5 parts of cassia seeds, 3 parts of mulberry leaves, 2 parts of angelica sinensis, 5 parts of cistanche deserticola, 10 parts of tangerine peel, 10 parts of honey, 5 parts of oligofructose, and 40 parts of deionized water.

[0034] The preparation of the active composition comprises the following steps: Step S1, after washing the hemp seed, baking it at 60° C. for 2 hours, and crushing it through a 100-mesh sieve to obtain hemp seed powder; adding deionized water to the hemp seed powder, stirring it at a stirring speed of 200 rpm for 10 minutes, mixing it evenly, and obtaining a slurry; adjusting the pH value of the slurry to 7.0, adding a composite enzyme preparation, wherein the amount of the composite enzyme preparation added is 0.5% of the mass of the hemp seed powder, enzymolyzing it at 50° C. for 3 hours, filtering, and collecting the filtrate to obtain a hemp seed enzymatic hydrolyzate, wherein the mass ratio of the hemp seed powder to the deionized water is 25:100, and the composite enzyme preparation is composed of flavor protease and papain in a mass ratio of 5:1; Step S2, washing the Prunus mume and the citron, crushing them through a 100-mesh sieve to obtain a mixed powder, adding deionized water to the mixed powder, and mixing them evenly to obtain a mixed solution; heating the mixed solution to 90° C., holding for 10 minutes, and naturally cooling it to 30° C., inoculating the composite probiotics in an amount of 3% of the mass of the mixed solution, and performing anaerobically fermentation for 2 days at a temperature of 35° C. and a fermentation pH of 5.5. Filtering to obtain a composite fermentation liquid, wherein the mass ratio of the mixed powder to deionized water is 30:80, the composite probiotics are composed of Bifidobacterium bifidum, Lactobacillus rhamnosus, and Lactobacillus reuteri in a mass ratio of 10:3:1, and the mass ratio of hemp seed, Prunus mume, and citron is 5:3:1; Step S3: mixing the hemp seed enzymatic hydrolysate and the composite fermentation liquor, adding maltodextrin, mixing evenly, and freeze-drying to obtain an active composition, wherein the amount of maltodextrin added is 10% of the total mass of the hemp seed enzymatic hydrolysate and the composite fermentation liquor.

[0035] A method for preparing a medicinal and edible product for moistening the intestines and promoting bowel movements, comprising the following steps: Honey and oligofructose are added to deionized water, stirred at a speed of 300 rpm for 10 minutes, and mixed evenly to obtain a mixed syrup; Cassia seed, mulberry leaf, angelica, Cistanche deserticola and tangerine peel are washed and dried, crushed through a 200-mesh sieve, added to the mixed syrup, stirred at a speed of 200 rpm for 10 minutes, and mixed evenly; the active composition is added, stirred at a speed of 100 rpm for 5 minutes, and mixed evenly to obtain a medicinal and edible product for moistening the intestines and promoting bowel movements.

[0036] Comparative Example 3 A medicinal and edible product for moistening the intestines and promoting bowel movements comprises the following raw materials in parts by weight: 30 parts of an active ingredient, 5 parts of cassia seeds, 3 parts of mulberry leaves, 2 parts of angelica sinensis, 5 parts of cistanche deserticola, 10 parts of tangerine peel, 10 parts of honey, 5 parts of oligofructose, and 40 parts of deionized water.

[0037] The preparation of the active composition comprises the following steps: Step S1, after washing the hemp seed, baking it at 60° C. for 2 hours, and crushing it through a 100-mesh sieve to obtain hemp seed powder; adding deionized water to the hemp seed powder, stirring it at a stirring speed of 200 rpm for 10 minutes, and mixing it evenly to obtain a slurry; adjusting the pH value of the slurry to 7.0, adding a composite enzyme preparation, wherein the amount of the composite enzyme preparation added is 0.5% of the mass of the hemp seed powder, enzymolyzing it at 50° C. for 3 hours, filtering, and collecting the filtrate to obtain a hemp seed enzymatic hydrolyzate, wherein the mass ratio of the hemp seed powder to the deionized water is 25:100, and the composite enzyme preparation is composed of flavor protease, bromelain, and papain in a mass ratio of 5:3:1; Step S2, washing the Prunus mume and the citron, crushing them through a 100-mesh sieve to obtain a mixed powder, adding deionized water to the mixed powder, and mixing them evenly to obtain a mixed solution; heating the mixed solution to 90° C., holding for 10 minutes, and naturally cooling it to 30° C., inoculating the composite probiotics in an amount of 3% of the mass of the mixed solution, and anaerobically fermenting them for 2 days at a temperature of 35° C. and a fermentation pH of 5.5. Filtering to obtain a composite fermentation liquid, wherein the mass ratio of the mixed powder to deionized water is 30:80, the composite probiotics are composed of Bifidobacterium bifidum and Lactobacillus rhamnosus in a mass ratio of 10:3, and the mass ratio of hemp seed, Prunus mume and citron is 5:3:1; Step S3: mixing the hemp seed enzymatic hydrolysate and the composite fermentation liquor, adding maltodextrin, mixing evenly, and freeze-drying to obtain an active composition, wherein the amount of maltodextrin added is 10% of the total mass of the hemp seed enzymatic hydrolysate and the composite fermentation liquor.

[0038] A method for preparing a medicinal and edible product for moistening the intestines and promoting bowel movements, comprising the following steps: Honey and oligofructose are added to deionized water, stirred at a speed of 300 rpm for 10 minutes, and mixed evenly to obtain a mixed syrup; Cassia seed, mulberry leaf, angelica, Cistanche deserticola and tangerine peel are washed and dried, crushed through a 200-mesh sieve, added to the mixed syrup, stirred at a speed of 200 rpm for 10 minutes, and mixed evenly; the active composition is added, stirred at a speed of 100 rpm for 5 minutes, and mixed evenly to obtain a medicinal and edible product for moistening the intestines and promoting bowel movements.

[0039] Comparative Example 4 A medicinal and edible product for moistening the intestines and promoting bowel movements comprises the following raw materials in parts by weight: 30 parts of an active ingredient, 5 parts of cassia seeds, 3 parts of mulberry leaves, 2 parts of angelica sinensis, 5 parts of cistanche deserticola, 10 parts of tangerine peel, 10 parts of honey, 5 parts of oligofructose, and 40 parts of deionized water.

[0040] The preparation of the active composition comprises the following steps: Step S1, washing hemp seed, Prunus mume seed and citron, baking them at 60° C. for 2 hours, and crushing them through a 100-mesh sieve to obtain hemp seed powder; adding deionized water to the hemp seed powder, stirring at a stirring speed of 200 rpm for 10 minutes, and mixing uniformly to obtain a slurry; adjusting the pH value of the slurry to 7.0, adding a composite enzyme preparation, wherein the amount of the composite enzyme preparation added is 0.5% of the mass of the hemp seed powder, enzymolyzing at 50° C. for 3 hours, filtering, and collecting the filtrate to obtain an enzymatic solution, wherein the mass ratio of hemp seed powder to deionized water is 25:100, the composite enzyme preparation is composed of flavor protease, bromelain and papain in a mass ratio of 5:3:1, and the mass ratio of hemp seed, Prunus mume seed and citron is 5:3:1; Step S2: adding maltodextrin to the enzymatic hydrolysate, mixing evenly, and freeze-drying to obtain an active composition. The amount of maltodextrin added is 10% of the mass of the enzymatic hydrolysate.

[0041] A method for preparing a medicinal and edible product for moistening the intestines and promoting bowel movements, comprising the following steps: Honey and oligofructose are added to deionized water, stirred at a speed of 300 rpm for 10 minutes, and mixed evenly to obtain a mixed syrup; Cassia seed, mulberry leaf, angelica, Cistanche deserticola and tangerine peel are washed and dried, crushed through a 200-mesh sieve, added to the mixed syrup, stirred at a speed of 200 rpm for 10 minutes, and mixed evenly; the active composition is added, stirred at a speed of 100 rpm for 5 minutes, and mixed evenly to obtain a medicinal and edible product for moistening the intestines and promoting bowel movements.

[0042] Comparative Example 5 A medicinal and edible product for moistening the intestines and promoting bowel movements comprises the following raw materials in parts by weight: 30 parts of an active ingredient, 5 parts of cassia seeds, 3 parts of mulberry leaves, 2 parts of angelica sinensis, 5 parts of cistanche deserticola, 10 parts of tangerine peel, 10 parts of honey, 5 parts of oligofructose, and 40 parts of deionized water.

[0043] The preparation of the active composition comprises the following steps: Step S1, after washing hemp seed, Prunus mume seed and citron, crushing them through a 100-mesh sieve to obtain a mixed powder, adding deionized water to the mixed powder, mixing evenly, and obtaining a mixed solution; heating the mixed solution to 90° C., holding for 10 minutes, naturally cooling to 30° C., inoculating composite probiotics, the inoculation amount being 3% of the mass of the mixed solution, at a temperature of 35° C., a fermentation pH of 5.5, performing anaerobically fermentation for 2 days, filtering, and obtaining a composite fermentation liquid, wherein the mass ratio of the mixed powder to deionized water is 30:80, the composite probiotics are composed of Bifidobacterium bifidum, Lactobacillus rhamnosus and Lactobacillus reuteri in a mass ratio of 10:3:1, and the mass ratio of hemp seed, Prunus mume seed and citron is 5:3:1; Step S2, malt dextrin is added into the compound fermentation liquor, after uniform mixing, freeze-drying, to obtain the active composition, the addition amount of malt dextrin is 10% of the mass of the compound fermentation liquor.

[0044] A preparation method of a medicinal and edible product for lubricating intestines and defecating, comprising the following preparation steps: The honey and fructooligosaccharide are added into the deionized water, stirred and mixed for 10 min at a stirring speed of 300 rpm, and then uniformly mixed to obtain a mixed syrup; the Cassia seed, mulberry leaf, angelica, cistanche and dried tangeret peel are washed, dried, crushed and passed through a 200-mesh sieve, then added into the mixed syrup, stirred and mixed for 10 min at a stirring speed of 200 rpm, and then uniformly stirred to obtain a mixture; the active composition is added into the mixture, stirred and mixed for 5 min at a stirring speed of 100 rpm, and then uniformly stirred to obtain the medicinal and edible product for lubricating intestines and defecating.

[0045] Comparative example 6 A medicinal and edible product for lubricating intestines and defecating, comprising the following raw materials in parts by weight: active composition 30 parts, Cassia seed 5 parts, mulberry leaf 3 parts, angelica 2 parts, cistanche 5 parts, dried tangeret peel 10 parts, honey 10 parts, fructooligosaccharide 5 parts, and deionized water 40 parts.

[0046] The preparation of the active composition comprises the following preparation steps: Step S1, the Prunus domestica and bergamot are washed, baked at 60℃ for 2 h, crushed and passed through a 100-mesh sieve to obtain a mixed powder; the mixed powder is added into deionized water, stirred and mixed for 10 min at a stirring speed of 200 rpm, and then uniformly mixed to obtain a slurry; the pH value of the slurry is adjusted to 7.0, a compound enzyme preparation is added, and the addition amount of the compound enzyme preparation is 0.5% of the mass of the mixed powder; the enzyme is hydrolyzed at 50℃ for 3 h, filtered, and the filtrate is collected to obtain a mixed enzyme hydrolysate; the mass ratio of the mixed powder to the deionized water is 25:100; the compound enzyme preparation is composed of flavor protease, bromelain and papain at a mass ratio of 5:3:1; Step S2, the Cannabis sativa L. is washed, crushed and passed through a 100-mesh sieve to obtain Cannabis sativa L. powder; the Cannabis sativa L. powder is added into deionized water, uniformly mixed to obtain a Cannabis sativa L. powder mixture; the Cannabis sativa L. powder mixture is heated to 90℃ and kept for 10 min, naturally cooled to 30℃, inoculated with a compound probiotic, and the inoculation amount is 3% of the mass of the Cannabis sativa L. powder mixture; the fermentation is carried out at a temperature of 35℃ and a pH of 5.5 for 2 days in an anaerobic environment, filtered to obtain a Cannabis sativa L. fermentation liquor; the mass ratio of the Cannabis sativa L. powder to the deionized water is 30:80; the compound probiotic is composed of Bifidobacterium bifidum, Lactobacillus rhamnosus and Lactobacillus reuteri at a mass ratio of 10:3:1; the mass ratio of the Cannabis sativa L., Prunus domestica and bergamot is 5:3:1; Step S3: mixing the mixed enzymolysis solution and the hemp seed fermentation liquid, adding maltodextrin, mixing evenly, and freeze-drying to obtain an active composition, wherein the amount of maltodextrin added is 10% of the total mass of the mixed enzymolysis solution and the hemp seed fermentation liquid.

[0047] A method for preparing a medicinal and edible product for moistening the intestines and promoting bowel movements, comprising the following steps: Honey and oligofructose are added to deionized water, stirred at a speed of 300 rpm for 10 minutes, and mixed evenly to obtain a mixed syrup; Cassia seed, mulberry leaf, angelica, Cistanche deserticola and tangerine peel are washed and dried, crushed through a 200-mesh sieve, added to the mixed syrup, stirred at a speed of 200 rpm for 10 minutes, and mixed evenly; the active composition is added, stirred at a speed of 100 rpm for 5 minutes, and mixed evenly to obtain a medicinal and edible product for moistening the intestines and promoting bowel movements.

[0048] The performance tests of the medicinal and edible products for moistening the intestine and relieving constipation prepared in Examples 1-3 and Comparative Examples 1-6 were conducted: Patient source: 270 constipation patients were recruited from a hospital in this city. The constipation grades of the patients were grade I, II, and III, including 135 grade I patients, 108 grade II patients, and 27 grade III patients. Among them, there were 132 male patients and 138 female patients. The average age of the patients was 30-40 years old, and the average duration of illness was 4-6 years. Constipation symptom classification: Grade I: Stool is defecate every 2-3 days and is dry; Grade II: Stool is defecate every 5-7 days, dry, with abdominal distension and prolonged defecation time; Grade III: No bowel movement for more than ten days, severe abdominal distension, fullness and dryness, flushed face, shortness of breath, bad breath, thirst, intestinal shape can sometimes be seen in abdominal examination, accompanied by hemorrhoids, anal fissures, rectal prolapse, pelvic congestion syndrome, etc.

[0049] Treatment method: Patients were divided into 9 groups according to age, gender, duration of illness and constipation condition, with 30 patients in each group. There was no significant difference between the groups. The patients were treated with the medicinal and edible products for moistening the intestines and relieving constipation prepared in Examples 1-3 and Comparative Examples 1-6, 100 mL each time, 3 times a day, for 14 consecutive days; the accompanying symptoms disappeared; Effective: The bowel movements were smooth, once a day or once every two days, sometimes dry; Efficacy criteria: Markedly effective: smooth bowel movements, once a day, moderate hardness, improved appetite, and disappearance of accompanying symptoms; Effective: smooth bowel movements, once a day or once every two days, sometimes dry; Ineffective: No significant improvement in constipation.

[0050] Table 1 Performance parameters of the medicinal and edible products for moistening the intestines and relieving constipation prepared in Examples 1-3 and Comparative Examples 1-6 Significantly effective efficient invalid Total effective rate (%) Example 1 23 6 1 96.67 Example 2 21 7 2 93.33 Example 3 25 5 0 100 Comparative Example 1 17 8 5 83.33 Comparative Example 2 15 10 5 83.33 Comparative Example 3 12 12 6 80 Comparative Example 4 16 10 4 86.67 Comparative Example 5 17 6 7 76.67 Comparative Example 6 15 8 7 76.67 As can be seen from Table 1, the medicinal and edible product for moistening the intestine and relieving constipation prepared in the present application relies on the lubrication and repair of hemp seed hydrolysate, the regulation of intestinal motility and flora by fermented Prunus mume seed and probiotics, the enhanced peristalsis effect of Chinese medicinal materials such as cassia seed and mulberry leaf, and the synergistic enhancement of honey and oligofructose, to improve defecation in multiple dimensions, and has a significant and effective effect in moistening the intestine and relieving constipation.

[0051] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make non-creative modifications to the present embodiment as needed, but as long as they are within the scope of the claims of the present application, they are protected by the patent law.

Claims

1. A medicinal and edible product for moistening the intestines and relieving constipation, characterized in that: The invention comprises the following raw materials in parts by weight: 30-45 parts of active composition, 5-15 parts of cassia seeds, 3-10 parts of mulberry leaves, 2-10 parts of angelica sinensis, 5-8 parts of cistanche deserticola, 10-15 parts of tangerine peel, 10-30 parts of honey, 5-15 parts of oligofructose and 40-60 parts of deionized water.

2. The food-drug product for moistening the intestines and relieving constipation according to claim 1, characterized in that: The preparation of the active composition comprises the following preparation steps: Step S1, after washing the hemp seed, baking it at 60-80° C. for 2-3 hours, crushing and sieving to obtain hemp seed powder; adding deionized water to the hemp seed powder, mixing uniformly to obtain a slurry; adjusting the pH value of the slurry to 7.0-7.5, adding a complex enzyme preparation, enzymolyzing it at 50-55° C. for 3-5 hours, filtering, and collecting the filtrate to obtain a hemp seed enzymolysis solution; Step S2: Wash the Prunus mume seeds and the citron, crush and sieve to obtain a mixed powder, add deionized water to the mixed powder, and mix evenly to obtain a mixed solution; heat the mixed solution to 90-100° C., maintain for 10-15 minutes, cool naturally to 30-37° C., inoculate with composite probiotics, perform anaerobically fermentation for 2-3 days, and filter to obtain a composite fermentation liquid; Step S3: mixing the hemp seed enzymatic hydrolysate and the composite fermentation liquid, adding a protective agent, mixing evenly, and drying at low temperature to obtain an active composition.

3. The food-drug product for moistening the intestines and relieving constipation according to claim 2, characterized in that: The mass ratio of hemp seed, Prunus mume seed and citron is 5-15:3-10:1-4.

4. The food-medicinal product for moistening the intestines and relieving constipation according to claim 2, characterized in that: The complex enzyme preparation consists of flavor protease, bromelain and papain in a mass ratio of 5-8:3-5:1-2.

5. The food-medicinal product for moistening the intestines and relieving constipation according to claim 2, characterized in that: The added amount of the complex enzyme preparation is 0.5-2.0% of the mass of the hemp seed powder.

6. The food-medicinal product for moistening the intestines and relieving constipation according to claim 2, characterized in that: The inoculation amount of the composite probiotics is 3-5% of the mass of the mixed solution.

7. The food-medicinal product for moistening the intestines and relieving constipation according to claim 2, characterized in that: The anaerobic fermentation temperature of the composite probiotics is 35-37° C., and the fermentation pH is 5.5-7.

0.

8. The food-medicinal product for moistening the intestines and relieving constipation according to claim 2, characterized in that: The composite probiotics consist of Bifidobacterium bifidum, Lactobacillus rhamnosus and Lactobacillus reuteri in a mass ratio of 10-12:3-8:1-3.

9. The food-medicinal product for moistening the intestines and relieving constipation according to claim 1, characterized in that: The protective agent is one or more of trehalose, mannitol, maltodextrin, glycerol, polyvinyl pyrrolidone and hydroxypropyl methylcellulose.

10. A method for preparing the intestinal moistening and laxative medicinal and edible product according to any one of claims 1 to 9, characterized in that: The method comprises the following preparation steps: Honey and oligofructose are added to deionized water and mixed evenly to obtain a mixed syrup; Cassia seed, mulberry leaf, angelica, Cistanche deserticola and dried tangerine peel are washed and dried, crushed and sieved, and added to the mixed syrup and stirred evenly; then the active composition is added and stirred evenly to obtain a medicinal and edible product for moistening the intestines and promoting bowel movements.