A contact lens silicone hydrogel polymer material and method of making the same

By introducing specific monomers and functional nanoparticles into silicone hydrogel materials for contact lenses, and combining them with pH-responsive borate ester bonds, the biocompatibility and wearing comfort issues of silicone hydrogel materials have been resolved, achieving high oxygen permeability and anti-inflammatory and antibacterial effects.

CN120757961BActive Publication Date: 2026-08-18IRIS (XIAMEN) TECH CO LTD
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Patent Information

Application Number
CN202510823268.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-06-19
Publication Date
2026-08-18
Estimated Expiration
2045-06-19

AI Technical Summary

Technical Problem

While existing silicone hydrogel materials for contact lenses improve oxygen permeability, they also have problems such as poor biocompatibility, easy adsorption of microorganisms leading to inflammatory reactions, and strong dryness when worn.

Method used

Cyclopentadimethylsiloxane and methacryloyloxypropyltris(trimethylsiloxy)silane are used as siloxane monomers, combined with N,N-dimethylacrylamide and hydroxyethyl methacrylate as hydrophilic monomers, and dynamic crosslinking agent 4-vinylphenylboronic acid is added. Polylactic acid-glycolic acid copolymer nanoparticles are encapsulated with ε-polylysine and resveratrol. The dopamine-modified nanoparticles bind to corneal mucin to form pH-responsive borate ester bonds, thereby achieving sustained release and self-repair of the material.

Benefits of technology

It improves the oxygen permeability of the material, reduces the risk of microbial adsorption, alleviates the dryness when wearing, extends the service life, and enhances safety and comfort.

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Abstract

The application discloses a kind of silicon hydrogel polymer materials for contact lenses and preparation method thereof, it is related to polymer material field, siloxane monomer, hydrophilic monomer and dynamic crosslinking agent are mixed to obtain monomer mixed solution;Functional nanoparticles, monomer mixed solution and initiator are mixed to obtain prepolymer liquid;The prepolymer liquid is injected into mould, and then demoulding is irradiated by ultraviolet light, and immersion is obtained, and the silicon hydrogel polymer material for contact lenses is obtained, the application utilizes cyclic siloxane monomer and linear siloxane copolymerization, forms controllable hydrophobic micro area, optimizes oxygen permeability, introduces borate bond as dynamic crosslinking point, network reconfiguration when ocular inflammation, release functional nanoparticles load's anti-inflammatory antibacterial component, and obtained high oxygen permeability, intelligent anti-inflammatory antibacterial and super durable comfortable silicon hydrogel polymer material for contact lenses.
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