Dialysis concentrated solution preparation system

Abstract

A dialysis concentrated solution preparation system comprises a main machine, a dialysis powder bag body and accessories, the main machine is an all-in-one machine and comprises a plurality of independently controlled dissolution stations, each station is provided with a multi-mode dissolution device, and the multi-mode dissolution device integrates three working modes of a mechanical shaking mechanism, an ultrasonic generator and a magnetic stirrer. The hemodialysis powder bag body comprises a flexible bag body, the flexible bag body is designed to be foldable, and hemodialysis dry powder is contained in the flexible bag body. The dialysate can be prepared and used on site, and the efficient and flexible liquid preparation effect is achieved through the liquid preparation system.

Description

Technical Field

[0001] This utility model relates to the field of medical equipment technology, and in particular to a dialysis concentrate preparation system. Background Technology

[0002] The composition of dialysate directly affects the clinical condition and prognosis of hemodialysis patients. Individual differences exist among hemodialysis patients, especially for those with specific conditions. Therefore, the prescription content of dialysate needs continuous improvement and updating as the patient's condition progresses to maintain physiological electrolyte and acid-base balance. Using personalized prescription dialysate can reduce the occurrence of dialysis complications. Providing dialysate with different ion concentrations reflects the quality of dialysis in hospitals and is an important part of achieving individualized clinical treatment; it also solves the problem of fluid supply for home hemodialysis. The company has conducted research and development on hemodialysis concentrates with personalized dialysis formulations.

[0003] Meanwhile, the existing model suffers from high costs in transporting, storing, and packaging concentrated solutions. Furthermore, changes in the electrolyte's physicochemical properties during storage and transportation can lead to a decline in dialysis quality (such as sodium bicarbonate crystallization). There is also a risk of concentrated solution contamination during centralized supply delivery. Currently available hemodialysis products are packaged in plastic containers, requiring a dedicated hemodialysis machine for preparation. These rigid plastic containers are prone to breakage during transport, and their weight also hinders patient mobility. Using dialysis powder or concentrated solutions still necessitates transferring them to new containers for dilution, leading to potential contamination and inconvenience. The new containers also increase costs. Utility Model Content

[0004] The present invention aims to solve at least one of the technical problems existing in the prior art. To this end, the present invention proposes a dialysis concentrate preparation system and a dynamic preparation control method, the specific technical solution of which is as follows:

[0005] This utility model provides a dialysis concentrate preparation system, including a main unit, dialysis powder bags, and supporting components. The main unit is an integrated machine, comprising: multiple independently controlled dissolution stations, each equipped with a multi-modal dissolution device integrating a mechanical shaking mechanism, an ultrasonic generator, and a magnetic stirrer for three working modes; each dissolution station also has a transmittance sensor located on the side of the dialysis powder bag; a temperature-controlled circulation pipeline with a built-in RO water heating module and temperature sensor; a distributed control unit including a PLC module and an HMI human-machine interface, the PLC module having a built-in memory pre-stored dissolution parameter combinations corresponding to different dialysis powder types; and a robotic arm with an end effector. The device includes pneumatic grippers that are adapted to the connector of the dialysis powder bag to connect the outlet of the temperature-controlled circulation pipeline to the liquid inlet of the dialysis powder bag. The dialysis powder bag includes a flexible bag body with a foldable design, containing hemodialysis powder. A lid is used to seal the opening of the flexible bag, and the lid has a connector for installing the dialysis powder bag at the dissolution station. The lid has a liquid inlet and a suction tube inlet for directly adding water to dissolve the dialysis powder, and forms an airtight connection with the docking port of the dissolution station through a self-locking quick connector. The accessories include a dialysis machine suction tube filter and a dialysis powder bag storage container.

[0006] Furthermore, the PLC module's memory pre-stores combinations of dissolution parameters corresponding to different powder types, including ultrasonic power, shaking frequency, and stirring speed; the transmittance sensor is connected to the PLC module via a signal line and feeds back transmittance data to the HMI human-machine interface in real time.

[0007] Furthermore, the cover is also provided with a drug dispensing port, and the distributed control unit controls the robotic arm to perform drug dispensing operations.

[0008] Furthermore, the dialysis machine's suction tube filter element has an average pore size of 20 μm, which can filter particles and undissolved powder.

[0009] Furthermore, the host is also equipped with an automatic alarm, which includes an audible and visual alarm light and a leakage detection circuit, the leakage detection circuit being located at the bottom of the dissolving station.

[0010] Furthermore, the main unit is also equipped with a timed cleaning device, which is connected to the temperature-controlled circulation pipeline.

[0011] Furthermore, the host unit is also equipped with a timed disinfection device, which is connected to the temperature-controlled circulation pipeline.

[0012] The technical solution of this utility model has the following advantages:

[0013] This invention uses a flexible bag containing hemodialysis dry powder, allowing for direct water addition and solution preparation within the bag. The dialysis powder dissolves and is prepared within the original bag, avoiding infections during concentrate transfer. It also solves the problems of using large quantities of medical-grade plastic particles to make barrels for bottled dialysis solution and the waste disposal of used barrels. This enables applications in three major scenarios: on-site preparation and use in hospitals, home dialysis, and personalized treatment. The concentrate volume is reduced by 20%, lowering the transportation breakage rate and storage space requirements. Furthermore, the dialysis concentrate preparation system employs multimodal collaborative dissolution technology: by combining mechanical shaking (3mm amplitude / 3Hz frequency), ultrasonic cavitation (28kHz / 200W), and magnetic stirring (300rpm) in a sequential manner, the dissolution time is shortened to 58 minutes; dynamic preparation logic: based on the powder feature code, historical data is automatically retrieved to optimize parameters, improving dissolution efficiency compared to the traditional fixed parameter mode; distributed supply architecture: multiple independent workstations can process different prescriptions in parallel or collaboratively supply high-demand scenarios, greatly improving system throughput; and an intelligent robotic arm is used to achieve flexibility and safety in automatic liquid and drug addition, improving production efficiency. Attached Figure Description

[0014] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments consistent with the present invention and, together with the description, serve to explain the principles of the present invention.

[0015] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0016] Figure 1 This is a schematic diagram of the dialysis concentrate preparation system provided in an embodiment of the present invention;

[0017] Figure 2 This is a schematic diagram of the multimodal dissolution device at the dissolution station provided in an embodiment of the present invention.

[0018] Figure 3 A schematic diagram of the temperature control circulation pipeline structure provided in this embodiment of the utility model;

[0019] Figure 4 A schematic diagram of the cover interface structure provided in an embodiment of this utility model;

[0020] Figure 5 A schematic diagram of the supporting components provided for an embodiment of this utility model.

[0021] Figure label:

[0022] 100. Main unit; 110. Dissolving station; 111. Multimodal dissolving device; 111a. Mechanical shaking mechanism; 111b. Ultrasonic generator; 111c. Magnetic stirrer; 120. Temperature-controlled circulation pipeline; 121. RO water heating module; 122. Temperature sensor; 130. Distributed control unit; 131. PLC; 132. HMI (Human-Machine Interface); 140. Robotic arm; 200. Dialysis powder bag; 210. Flexible bag; 220. Lid; 221. Connector; 222. Liquid inlet; 223. Suction tube inlet; 225. Drug inlet; 240. Powder bag RFID tag; 300. Accessories; 310. Dialysis machine suction tube filter element; 320. Dialysis powder bag placement container; 113. Light transmittance sensor. Detailed Implementation

[0023] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0024] This utility model relates to a dialysis concentrate preparation system and its control method, aiming to achieve efficient dissolution and precise preparation of dialysis dry powder through automated and intelligent equipment design. The technical solution of this utility model is described in detail below with reference to specific embodiments.

[0025] I. System Structure and Functional Modules

[0026] 1. Structure and Function of Main Unit 100

[0027] Dissolving Station 110: The main unit is equipped with multiple independently controlled dissolving stations, each equipped with a multimodal dissolving device 111. The multimodal dissolving device integrates three working modes: a mechanical shaking mechanism 111a, an ultrasonic generator 111b, and a magnetic stirrer 111c. These three modes can be used individually or in combination to meet the dissolving needs of different powder types.

[0028] The dissolution station 110 is also equipped with a light transmittance sensor 113, located on the side of the dialysis powder bag 200.

[0029] Temperature-controlled circulation pipeline 120: Built-in RO water heating module 121 and temperature sensor 122, used to precisely control the liquid addition temperature and ensure that the powder dissolves at the optimal temperature.

[0030] Distributed control unit 130: Employs a PLC 131 and an HMI (Human-Machine Interface) 132 working collaboratively. The PLC is configured with a dissolution mode decision algorithm, which can automatically select the optimal combination of dissolution modes based on the powder type. The PLC module 131 has a built-in memory 133, which pre-stores dissolution parameter combinations corresponding to different dialysis powder types.

[0031] Robotic arm 140: Used to connect the temperature-controlled circulation pipeline 120 and the dialysis powder bag 200 to realize the liquid addition operation of the dialysis powder bag. The end is equipped with a pneumatic gripper 141, which is adapted to the connector 221 of the dialysis powder bag 200 to connect the water outlet of the temperature-controlled circulation pipeline 120 to the liquid addition port 222 of the dialysis powder bag 200.

[0032] 2. Structure and function of dialysis powder bag 200

[0033] Flexible bag 210: It adopts a foldable design and is filled with hemodialysis dry powder.

[0034] Lid 220: Used to seal the opening of the flexible bag. The lid has a connector 221 for attaching the dialysis powder bag to the dissolution station. The lid also has a liquid inlet 222 and a pipette inlet 223, which form an airtight connection with the dissolution station's docking port via a self-locking quick connector. Additionally, the lid has a drug dispensing port 225, for which a robotic arm controlled by a distributed control unit performs the drug dispensing operation.

[0035] 3. Matching parts 300

[0036] Dialysis machine suction tube filter element 310: with an average pore size of 20μm, used to filter particulates and undissolved powder.

[0037] Dialysis powder bag storage container 320: Used for storing dialysis powder bags.

[0038] II. Implementation of the Dissolution Mode Decision Algorithm

[0039] The specific implementation steps of the dissolution mode decision algorithm are as follows:

[0040] 1. Powder type identification: The powder type code is read by the RFID tag 240 on the powder bag, and the RO purified water is heated to the corresponding temperature before entering the dialysis powder bag 200.

[0041] 2. Parameter matching: The system calls up a pre-stored database to match the corresponding combination of dissolving parameters, including ultrasonic power, shaking frequency, stirring speed, etc., and automatically controls the amount of water to prepare a standard concentrated solution.

[0042] 3. Dynamic adjustment: The solubility is measured in real time by the transmittance sensor 113, and the dissolution parameters are dynamically adjusted based on the real-time data to ensure the efficiency and stability of the dissolution process.

[0043] The PLC module 131 has a memory 133 that stores combinations of dissolution parameters corresponding to different powder types, including ultrasonic power, shaking frequency and stirring speed; the transmittance sensor 113 is connected to the PLC module 131 through a signal line and feeds back transmittance data to the HMI human-machine interface 132 in real time.

[0044] III. Implementation of Drug Dosing Procedures

[0045] The dosing port 225 on the cap 220 is controlled by the distributed control unit 130. When medication is needed, the robotic arm 140 injects the medication into the dialysis powder bag through the dosing port according to the control instructions, thus completing the dosing operation.

[0046] IV. Implementation of Automatic Alarm and Cleaning / Disinfection Functions

[0047] 1. Automatic alarm: The main unit is equipped with an automatic alarm to monitor for leaks and other abnormalities in real time, and will promptly issue an alarm when an abnormality occurs.

[0048] 2. Timed cleaning: The main unit is equipped with a timed cleaning device, which can perform cleaning when the system is not in use, according to the preset time and program.

[0049] 3. Timed disinfection: The main unit is equipped with a timed disinfection device. The disinfection time and program are preset according to the equipment usage to ensure the cleanliness and hygiene of the equipment.

[0050] V. Implementation of Dynamic Solution Preparation Control Method for Dialysis Dry Powder

[0051] The specific implementation steps of the dynamic solution preparation control method for dialysis dry powder of this utility model are as follows:

[0052] 1. Establishment of a powder solubility feature library: Record the solubility-time curves of different powders and establish a powder solubility feature library.

[0053] 2. Learning Mode: When using a new powder for the first time, the learning mode is activated. The dissolution efficiency of the three basic modes—mechanical shaking, ultrasonic stirring, and magnetic stirring—and two combined modes are tested sequentially. The optimal parameter combination is generated and stored in the database.

[0054] 3. Dynamic optimization: During continuous production, the dissolution sequence is automatically optimized based on the current workstation load, prioritizing the processing of powder bags with high prescription urgency, thereby improving overall production efficiency.

[0055] This invention achieves efficient dissolution and precise solution preparation of dialysis dry powder through multimodal dissolution devices, intelligent control algorithms, and robotic arms. The system is automated and intelligent, significantly improving the efficiency and quality of dialysis concentrate preparation while reducing errors and risks associated with manual operation.

[0056] It should be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the exemplary embodiments according to this application. As used herein, the singular form is intended to include the plural form as well, unless the context clearly indicates otherwise. Furthermore, it should be understood that when the terms "comprising" and / or "including" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or combinations thereof.

[0057] Of course, the above are preferred embodiments of this utility model. It should be noted that, for those skilled in the art, several improvements and modifications can be made without departing from the basic principles of this utility model, and these improvements and modifications are also considered to be within the protection scope of this utility model.

Claims

1. A dialysis concentrate solution preparation system, comprising a host computer (100), a dialysis powder bag body (200) and a supporting kit (300), characterized in that, The host (100) is an all-in-one machine, comprising: A plurality of independently controlled dissolving stations (110), each station being provided with a multimodal dissolving device (111) integrating a mechanical shaking mechanism (111a), an ultrasonic generator (111b) and a magnetic stirrer (111c) in three working modes; the dissolving station (110) is further provided with a light transmittance sensor (113) located at the side of the dialysis powder bag (200); A temperature control circulation pipeline (120) with a built-in RO water heating module (121) and a temperature sensor (122); A distributed control unit (130) comprising a PLC module (131) and an HMI human-machine interface (132), the PLC module (131) being provided with a memory (133), the memory (133) pre-storing dissolving parameter combinations corresponding to different dialysis powder types; A robot arm (140) provided with a pneumatic gripper (141) at the end, the pneumatic gripper (141) being adapted to the connecting piece (221) of the dialysis powder bag (200) for connecting the water outlet of the temperature control circulation pipeline (120) with the liquid inlet (222) of the dialysis powder bag (200); The dialysis powder bag (200) comprises: A flexible bag (210) with a foldable design, the flexible bag being provided with hemodialysis dry powder; A cover (220) for sealing the bag opening of the flexible bag, the cover being provided with a connecting piece (221) for mounting the dialysis powder bag on the dissolving station, the cover being provided with a liquid inlet (222) for directly dissolving the dialysis dry powder and a straw opening (223) for forming an airtight connection with the docking port of the dissolving station (110) through a self-locking quick connector; The kit (300) comprises: A dialysis machine pipette filter element (310) and a dialysis powder bag placing barrel (320).

2. The dialysis concentrate reconstitution system of claim 1, wherein, The memory (133) of the PLC module (131) pre-stores dissolving parameter combinations corresponding to different powder types, including ultrasonic power, shaking frequency and stirring speed; the light transmittance sensor (113) is connected with the PLC module (131) through a signal line and feeds back light transmittance data to the HMI human-machine interface (132) in real time.

3. The dialysis concentrate reconstitution system of claim 1, wherein, The cover (220) is further provided with a medicine inlet (225), and the distributed control unit (130) controls the robot arm (140) to perform medicine adding operation.

4. The dialysis concentrate reconstitution system of claim 1, wherein, The average pore size of the dialysis machine pipette filter element is 20 μm, which can filter particles and undissolved powder.

5. The dialysis concentrate reconstitution system of claim 1, wherein, The host is further provided with an automatic alarm, the automatic alarm comprising an audible and visual alarm lamp and a liquid leakage detection circuit, the liquid leakage detection circuit being arranged at the bottom of the dissolving station (110).

6. The dialysis concentrate reconstitution system of claim 1, wherein, The host is further provided with a timing cleaning device connected with the temperature control circulation pipeline (120).

7. The dialysis concentrate reconstitution system of claim 1, wherein, The host is further provided with a timing sterilization device connected with the temperature control circulation pipeline (120).

Images