Traditional Chinese medicine composition capable of invigorating spleen to promote digestion as well as preparation method and application of traditional Chinese medicine composition

By preparing a specific ratio of traditional Chinese medicine composition for strengthening the spleen and promoting digestion, the problem of poor efficacy of traditional Chinese medicine has been solved, the symptoms of functional dyspepsia have been significantly relieved, the digestive function of the spleen and stomach has been enhanced, and the quality of life of patients has been improved.

CN120789201APending Publication Date: 2025-10-17CHENGDU HI-TECH SOUTHWEST CHILDRENS REHABILITATION HOSPITAL CO LTD
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Patent Information

Application Number
CN202511074752.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-08-01
Publication Date
2025-10-17

AI Technical Summary

Technical Problem

Existing traditional Chinese medicine treatments for functional dyspepsia are ineffective and cannot effectively address symptoms such as spleen and stomach weakness and food stagnation. Furthermore, Western medicine treatments are prone to relapse upon discontinuation and cannot improve comorbid anxiety and depression.

Method used

A traditional Chinese medicine composition for strengthening the spleen and promoting digestion is used, comprising herbs such as Bupleurum chinense, Paeonia lactiflora, Cinnamomum cassia, Citrus reticulata, Pinellia ternata, Atractylodes macrocephala, Trichosanthes kirilowii, Alisma plantago-aquatica, Allium macrostemon, Rheum palmatum, Citrus aurantium, and Curcuma zedoaria. These herbs are prepared into pills, granules, and other dosage forms through specific proportions and processing methods. They are used to regulate the spleen and stomach, harmonize Qi, and enhance digestive function.

Benefits of technology

It significantly relieves symptoms such as chest and abdominal fullness, loss of appetite, sallow complexion and emaciation, fatigue and weakness, belching and acid reflux, nausea and vomiting, abdominal pain and bloating, improves the therapeutic effect of traditional Chinese medicine, and reduces the risk of recurrence.

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Abstract

The invention discloses a spleen invigorating and digestion promoting traditional Chinese medicine composition and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition comprises the following components in parts by weight: 45-75 parts of bupleurum chinense, 35-65 parts of radix paeoniae alba, 35-65 parts of cassia twig, 120-180 parts of pericarpium citri reticulatae, 35-65 parts of pinellia ternate, 35-65 parts of bighead atractylodes rhizome, 35-65 parts of trichosanthes kirilowii maxim, 45-85 parts of rhizoma alismatis, 35-65 parts of allium macrostemon, 8-25 parts of rheum officinale, 35-65 parts of immature bitter orange and 35-65 parts of curcuma zedoary. All the medicines in the traditional Chinese medicine composition supplement each other to achieve the effects of invigorating spleen to promote digestion, promoting the circulation of qi to diuresis, reducing phlegm and removing dampness together, and the problem that an existing traditional Chinese medicine is poor in curative effect can be effectively solved.
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Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of traditional Chinese medicine, and particularly relates to a spleen-invigorating and food-digesting traditional Chinese medicine composition as well as a preparation method and application thereof. BACKGROUND

[0002] Functional dyspepsia is a common global digestive system disease, and patients often show postprandial fullness, upper abdominal pain, acid regurgitation, etc. Nausea, vomiting, acid reflux, heartburn, loss of appetite, etc. may occur, and some patients may be accompanied by anxiety, depression, insomnia and other psychological symptoms, which seriously affect the quality of life.

[0003] Western medicine believes that the etiology of the disease is not clear, and is related to the following factors:

[0004] 1. Gastrointestinal motility disorder, delayed gastric emptying, and decreased gastric accommodation relaxation function, leading to food retention in the stomach, causing fullness and early satiety;

[0005] 2. Visceral hypersensitivity, increased sensitivity of the gastrointestinal tract to stretching, traction and other stimuli, and slight stimulation can cause significant discomfort;

[0006] 3. Abnormal gastric acid secretion, and some patients have excessive gastric acid secretion or increased sensitivity of gastric acid to mucosa;

[0007] 4. Helicobacter pylori infection, which can induce or aggravate symptoms by affecting gastric mucosal inflammation and gastrointestinal hormone secretion;

[0008] Traditional Chinese medicine classifies it as fullness, stomach pain, upset stomach, belching, etc. The core pathogenesis is dysfunction of the spleen and stomach, and the specific causes are as follows:

[0009] 1. Improper diet, overeating, overeating cold, greasy or spicy and stimulating food, damaging the spleen and stomach, leading to abnormal transportation, food accumulation and qi stagnation;

[0010] 2. Emotional disorder, long-term worry, thinking and anger, leading to liver qi stagnation, stomach invasion, stomach dysfunction, and qi stagnation;

[0011] 3. Weakness of the spleen and stomach, insufficient congenital endowment, or overwork due to prolonged illness, leading to deficiency of spleen and stomach qi or yang deficiency, transportation failure, internal generation of dampness, and qi stagnation;

[0012] 4. Internal resistance of phlegm and dampness, abnormal transportation of the spleen and stomach, internal retention of water and dampness, accumulation of phlegm, and obstruction of phlegm and dampness in the middle jiao, affecting the ascending and descending of qi, and appearing fullness and abdominal distension;

[0013] Western medicine treatment mainly uses prokinetic drugs, digestive enzyme preparations and acid suppressants, but has limitations such as easy recurrence after drug withdrawal and inability to improve comorbid anxiety and depression; Traditional Chinese medicine treats according to syndrome differentiation, and achieves the purpose of treatment by regulating the spleen and stomach and regulating qi, but the current traditional Chinese medicine still has the problem of poor curative effect. SUMMARY

[0014] In view of the above problems in the prior art, the present application provides a spleen-invigorating and food-digesting traditional Chinese medicine composition, a preparation method and application thereof.

[0015] To achieve the above object, the technical scheme adopted by the present application to solve its technical problem is:

[0016] A spleen-invigorating and food-digesting traditional Chinese medicine composition, comprising the following components in parts by weight: Radix Bupleuri 45-75 parts, Radix Paeoniae Alba 35-65 parts, Ramulus Cinnamomi 35-65 parts, Pericarpium Citri Reticulatae 120-180 parts, Rhizoma Pinelliae 35-65 parts, Rhizoma Atractylodis Macrocephalae 35-65 parts, Fructus Trichosanthis 35-65 parts, Rhizoma Alismatis 45-85 parts, Bulbus Allii Macrostemonis 35-65 parts, Radix et Rhizoma Rhei 8-25 parts, Fructus Aurantii 35-65 parts and Rhizoma Curcumae 35-65 parts.

[0017] Further, the components include the following components in parts by weight: Radix Bupleuri 55-65 parts, Radix Paeoniae Alba 45-55 parts, Ramulus Cinnamomi 45-55 parts, Pericarpium Citri Reticulatae 140-160 parts, Rhizoma Pinelliae 45-55 parts, Rhizoma Atractylodis Macrocephalae 45-55 parts, Fructus Trichosanthis 45-55 parts, Rhizoma Alismatis 55-65 parts, Bulbus Allii Macrostemonis 45-55 parts, Radix et Rhizoma Rhei 10-20 parts, Fructus Aurantii 45-55 parts and Rhizoma Curcumae 45-55 parts.

[0018] Further, the components include the following components in parts by weight: Radix Bupleuri 65 parts, Radix Paeoniae Alba 55 parts, Ramulus Cinnamomi 55 parts, Pericarpium Citri Reticulatae 160 parts, Rhizoma Pinelliae 55 parts, Rhizoma Atractylodis Macrocephalae 55 parts, Fructus Trichosanthis 55 parts, Rhizoma Alismatis 65 parts, Bulbus Allii Macrostemonis 55 parts, Radix et Rhizoma Rhei 20 parts, Fructus Aurantii 55 parts and Rhizoma Curcumae 55 parts.

[0019] Further, the components include the following components in parts by weight: Radix Bupleuri 55 parts, Radix Paeoniae Alba 45 parts, Ramulus Cinnamomi 45 parts, Pericarpium Citri Reticulatae 140 parts, Rhizoma Pinelliae 45 parts, Rhizoma Atractylodis Macrocephalae 45 parts, Fructus Trichosanthis 45 parts, Rhizoma Alismatis 55 parts, Bulbus Allii Macrostemonis 45 parts, Radix et Rhizoma Rhei 10 parts, Fructus Aurantii 45 parts and Rhizoma Curcumae 45 parts.

[0020] Further, the components include the following components in parts by weight: Radix Bupleuri 60 parts, Radix Paeoniae Alba 50 parts, Ramulus Cinnamomi 50 parts, Pericarpium Citri Reticulatae 150 parts, Rhizoma Pinelliae 50 parts, Rhizoma Atractylodis Macrocephalae 50 parts, Fructus Trichosanthis 50 parts, Rhizoma Alismatis 60 parts, Bulbus Allii Macrostemonis 50 parts, Radix et Rhizoma Rhei 15 parts, Fructus Aurantii 50 parts and Rhizoma Curcumae 50 parts.

[0021] Further, the Radix Bupleuri is Radix Bupleuri in vinegar, the Radix Paeoniae Alba is Radix Paeoniae Alba that is stir-baked, the Fructus Aurantii is Fructus Aurantii that is roasted with bran, the Rhizoma Pinelliae is Rhizoma Pinelliae that is stir-baked with ginger, the Pericarpium Citri Reticulatae is Pericarpium Citri Reticulatae that is roasted with bran, the Rhizoma Atractylodis Macrocephalae is Rhizoma Atractylodis Macrocephalae that is roasted with bran, the Rhizoma Alismatis is Rhizoma Alismatis that is salted, and the Rhizoma Curcumae is Rhizoma Curcumae that is soaked in vinegar.

[0022] The preparation method of the above-mentioned Chinese medicine composition for strengthening the spleen and promoting digestion comprises the following steps: crushing the raw materials and then mixing them; or preparing the composition by mixing or extracting the raw materials separately to obtain an extract; or preparing the composition by further refining and purifying the extract to obtain an effective ingredient; or preparing the composition by adding pharmaceutically acceptable excipients to the extract / active ingredient.

[0023] Furthermore, the prepared dosage form is one of pills, granules, capsules, powders, mixtures, tablets, granules or oral liquids.

[0024] Furthermore, the specific preparation method is as follows: the above twelve ingredients are decocted with water, the filtrate is collected and concentrated to a relative density of 1.05-1.1, auxiliary materials are added thereto, mixed, and purified water is added to make up the volume to obtain the product.

[0025] Furthermore, water is added for decoction three times, with 12 times the weight of the medicinal materials added in water for the first time, and 10 times the weight of the medicinal materials added in water for the second and third times.

[0026] The application of the above-mentioned spleen-strengthening and digestion-promoting Chinese medicine composition in the preparation of spleen-strengthening and digestion-promoting medicines.

[0027] The beneficial effects produced by the present invention are:

[0028] Atractylodes macrocephala is sweet, bitter and warm, and enters the spleen and stomach meridians. It is an important medicine for strengthening the spleen and replenishing qi. In this application, Atractylodes macrocephala is used to strengthen the spleen and dry dampness, cultivate and replenish the acquired foundation, and restore the function of spleen and stomach transportation and transformation; Citrus aurantium is bitter, pungent and slightly cold, enters the spleen and stomach meridians, breaks up qi and eliminates accumulation, resolves phlegm and eliminates abdominal distension, and is used in combination with Atractylodes macrocephala to both eliminate and replenish. Atractylodes macrocephala strengthens the spleen to stop the source of accumulation, and Citrus aurantium eliminates accumulation to eliminate the stagnation of stagnation. The two are both monarch drugs, closely following the main symptoms of spleen and stomach weakness and food stagnation;

[0029] Tangerine peel is bitter, pungent and warm, enters the spleen and lung meridians, regulates qi and invigorates the spleen, dries dampness and resolves phlegm, not only helps Atractylodes macrocephala to invigorate the spleen and harmonize the middle, but also helps Citrus aurantium to eliminate qi stagnation, relieves chest and abdominal distension, belching and acid regurgitation; Pinellia ternata is pungent and warm, enters the spleen, stomach and lung meridians, dries dampness and resolves phlegm, descends adverse qi and stops vomiting, and is used for nausea, vomiting, and abdominal distension caused by food stagnation and phlegm-dampness in the middle, and is compatible with Tangerine peel to enhance the ability to resolve phlegm and soothe the stomach; Northern Bupleurum is bitter, pungent and slightly cold, enters the liver and gallbladder meridians, soothes the liver and relieves depression, and raises yang qi. Spleen and stomach weakness easily leads to liver depression invading the spleen, and Bupleurum soothes the liver and regulates qi, helps the spleen and stomach transport and transformation, and its ascending and dispersing nature can generate spleen and stomach clear yang, promote the ascending and descending of qi; cinnamon twig is pungent, sweet and warm, enters the heart, lung and bladder meridians, warms and unblocks the meridians, helps yang and transforms qi, can warm and transport spleen yang, to help Atractylodes macrocephala to invigorate the spleen, and at the same time warms and transforms water dampness, for irregular bowel movements caused by water dampness in the middle

[0030] Trichosanthes kirilowii is sweet, slightly bitter and cold, and enters the lung, stomach and large intestine meridians. It clears away heat, eliminates phlegm, relieves chest congestion and disperses stagnation. Food stagnation in the body can easily cause phlegm heat. Trichosanthes kirilowii relieves chest congestion and promotes qi circulation, and helps Zhishi and Tangerine peel to eliminate lumps and fullness. Its moisturizing and laxative properties can help clear the bowels and relieve stagnation. Xiebai is pungent, bitter and warm, and enters the heart, lung, stomach and large intestine meridians. It promotes yang and disperses stagnation, promotes qi circulation and relieves stagnation. It is good at relieving chest and abdominal distension. When used together with Trichosanthes kirilowii, it enhances the effect of promoting qi circulation and relieving bloating. Curcuma zedoaria, pungent, bitter, and warm, enters the liver and spleen meridians. It promotes qi circulation, dissipates blood circulation, and relieves pain. Long-term food accumulation can lead to qi and blood stasis. Curcuma zedoaria dissipates qi and eliminates accumulation, aided by Zhishi and Tangerine peel in digesting food and dissolving accumulation. It is particularly effective for those with severe abdominal distension and pain. Alisma orientalis, sweet, mild, and cold, enters the kidney and bladder meridians. It promotes diuresis, dissipates dampness, and relieves heat. Internal food accumulation often leads to dampness stagnation. Alisma orientalis dissipates dampness and promotes diuresis, allowing dampness to be expelled through urination, alleviating symptoms of sallow complexion, thinness, fatigue, and weakness. Rhubarb, bitter and cold, enters the spleen, stomach, and large intestine meridians. It is a purgative, attacking accumulation, clearing heat and purging fire. For severe food accumulation and bowel qi obstruction, rhubarb can purge the bowels and dissipate stagnation. Combining rhubarb with Zhishi and Curcuma zedoaria enhances its ability to dissipate accumulation and resolve stagnation. These five herbs are collectively referred to as adjuvants.

[0031] Tangerine peel and Pinellia ternata in this formula not only regulate qi and soothe the stomach, but also balance the properties of the other herbs, preventing those promoting qi and dissolving stagnation from damaging the body's health, while also acting as guiding herbs to harmonize the spleen and stomach. The combined effects of these herbs strengthen the spleen and aid digestion, promote qi and promote diuresis, and resolve phlegm and dampness. This formula is suitable for treating symptoms such as chest and epigastric fullness, loss of appetite, sallow complexion, thin body, fatigue, belching, acid regurgitation, aversion to food, vomiting, abdominal pain, bloating, and irregular urination caused by spleen and stomach deficiency and food stagnation. DETAILED DESCRIPTION

[0032] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention. That is, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments.

[0033] Therefore, the detailed description of the embodiments of the present invention provided below is not intended to limit the scope of the claimed invention, but is merely intended to represent selected embodiments of the present invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative work are within the scope of protection of the present invention.

[0034] It is to be understood that the terms "first" and "second" and similar relating terms are used merely to distinguish one entity or action from another, and do not necessarily require or imply any such actual relationship or order between such entities or actions. Also, the terms "comprising", "containing" or any other similar words are intended to encompass non-exclusive inclusion, so that a process, method, article or apparatus including a list of elements includes not only those elements, but also other elements not explicitly listed, or other elements inherent in such process, method, article or apparatus. Without more limitation, the element defined by the phrase "comprising a" does not exclude the presence of additional identical elements in the process, method, article or apparatus including the element.

[0035] The features and properties of the present application are described in further detail below in connection with embodiments.

[0036] Example 1

[0037] A traditional Chinese medicine composition for invigorating the spleen and eliminating food retention, comprising the following components in parts by weight: vinegar North Bupleurum 45 parts, fried white peony root 35 parts, cassia twig 35 parts, bran fried pericarpium citri reticulatae 120 parts, ginger pinellia 35 parts, white atractylodes 35 parts, trichosanthes 35 parts, salt lake sedge 45 parts, Chinese onion 35 parts, rhubarb 8 parts, bran fried Citrus aurantium 35 parts, and vinegar of the star 35 parts.

[0038] The preparation method comprises the following steps: decocting the above twelve ingredients with water, adding 12 times the weight of the medicinal material in water for the first time, adding 10 times the weight of the medicinal material in water for the second and third times, collecting the filtrate, and then concentrating to a relative density of 1.05-1.1, adding auxiliary materials thereto, mixing, adding purified water to constant volume, and preparing.

[0039] Example 2

[0040] A traditional Chinese medicine composition for invigorating the spleen and eliminating food retention, comprising the following components in parts by weight: vinegar North Bupleurum 75 parts, fried white peony root 65 parts, cassia twig 65 parts, bran fried pericarpium citri reticulatae 180 parts, ginger pinellia 65 parts, white atractylodes 65 parts, trichosanthes 65 parts, salt lake sedge 85 parts, Chinese onion 65 parts, rhubarb 25 parts, bran fried Citrus aurantium 65 parts, and vinegar of the star 65 parts.

[0041] The preparation method comprises the following steps: decocting the above twelve ingredients with water, adding 12 times the weight of the medicinal material in water for the first time, adding 10 times the weight of the medicinal material in water for the second and third times, collecting the filtrate, and then concentrating to a relative density of 1.05-1.1, adding auxiliary materials thereto, mixing, adding purified water to constant volume, and preparing.

[0042] Example 3

[0043] A spleen-strengthening and digestion-promoting Chinese medicinal composition comprises the following components in parts by weight: 65 parts of bupleurum root with vinegar, 55 parts of stir-fried white peony root, 55 parts of cassia twig, 160 parts of stir-fried dried tangerine peel with bran, 55 parts of pinellia tuber with ginger, 55 parts of atractylodes macrocephala, 55 parts of trichosanthes root, 65 parts of salt-soaked alisma orientalis, 55 parts of allium macrostemon, 20 parts of rhubarb, 55 parts of stir-fried immature aurantium with bran, and 55 parts of zedoaria with vinegar.

[0044] The preparation method comprises the following steps: boiling the above twelve herbs with water, adding 12 times the weight of the herbs for the first time, and adding 10 times the weight of the herbs for the second and third times, collecting the filtrate and concentrating it to a relative density of 1.05-1.1, adding auxiliary materials thereto, mixing well, and then adding purified water to make up the volume to obtain the product.

[0045] Example 4

[0046] A Chinese medicinal composition for invigorating the spleen and promoting digestion comprises the following components in parts by weight: 55 parts of bupleurum root with vinegar, 45 parts of stir-fried white peony root, 45 parts of cassia twig, 140 parts of stir-fried dried tangerine peel with bran, 45 parts of pinellia tuber with ginger, 45 parts of atractylodes macrocephala, 45 parts of trichosanthes root, 55 parts of zedoariae with salt, 45 parts of xiebai, 10 parts of rhubarb, 45 parts of stir-fried immature aurantium with bran, and 45 parts of zedoariae with vinegar.

[0047] The preparation method comprises the following steps: boiling the above twelve herbs with water, adding 12 times the weight of the herbs for the first time, and adding 10 times the weight of the herbs for the second and third times, collecting the filtrate and concentrating it to a relative density of 1.05-1.1, adding auxiliary materials thereto, mixing well, and then adding purified water to make up the volume to obtain the product.

[0048] Example 5

[0049] A Chinese medicinal composition for invigorating the spleen and promoting digestion comprises the following components in parts by weight: 60 parts of bupleurum root with vinegar, 50 parts of stir-fried white peony root, 50 parts of cassia twig, 150 parts of stir-fried dried tangerine peel with bran, 50 parts of pinellia tuber with ginger, 50 parts of atractylodes macrocephala, 50 parts of trichosanthes root, 60 parts of zedoariae with salt, 50 parts of xiebai, 15 parts of rhubarb, 50 parts of stir-fried immature aurantium with bran, and 50 parts of zedoariae with vinegar.

[0050] The preparation method comprises the following steps: boiling the above twelve herbs with water, adding 12 times the weight of the herbs for the first time, and adding 10 times the weight of the herbs for the second and third times, collecting the filtrate and concentrating it to a relative density of 1.05-1.1, adding auxiliary materials thereto, mixing well, and then adding purified water to make up the volume to obtain the product.

[0051] Comparative Example 1

[0052] A Chinese medicinal composition for strengthening the spleen and promoting digestion, comprising the following components in parts by weight: 60 parts of Cimicifuga heracleifolia, 50 parts of stir-fried white peony root, 50 parts of cassia twig, 80 parts of stir-fried dried tangerine peel with bran, 50 parts of ginger pinellia, 50 parts of atractylodes, 50 parts of hemp seed, 60 parts of salt-soaked alisma orientalis, 50 parts of Allium macrostemon, 15 parts of rhubarb, 50 parts of stir-fried immature bitter orange with bran, and 50 parts of vinegar-soaked zedoaria.

[0053] The preparation method comprises the following steps: decocting the twelve medicines with water, adding 12 times the weight of the medicinal materials in water for the first time, adding 10 times the weight of the medicinal materials in water for the second and third times, collecting the filtrate, and then adding excipients to the filtrate, uniformly mixing, and adding purified water to constant volume to obtain the product.

[0054] Comparative Example 2

[0055] A traditional Chinese medicine composition for invigorating the spleen and promoting digestion comprises the following components in parts by weight: 60 parts of vinegar-fried Bupleurum, 50 parts of fried white peony root, 50 parts of cassia twig, 150 parts of bran-fried dried tangerine or orange peel, 50 parts of bamboo shavings, 50 parts of white atractylodes, 50 parts of trichosanthes, 60 parts of polyporus, 50 parts of Chinese onion, 15 parts of rhubarb, 50 parts of bran-fried immature orange fruit, and 50 parts of sparganium.

[0056] The preparation method comprises the following steps: decocting the twelve medicines with water, adding 12 times the weight of the medicinal materials in water for the first time, adding 10 times the weight of the medicinal materials in water for the second and third times, collecting the filtrate, and then adding excipients to the filtrate, uniformly mixing, and adding purified water to constant volume to obtain the product.

[0057] Test Example

[0058] I. General information

[0059] 90 patients diagnosed with functional dyspepsia were selected, including 47 males and 43 females, aged 7-15 years old, with an average age of 10.8 years old;

[0060] II. Disease diagnosis standard:

[0061] Core symptoms: postprandial fullness, early satiety, epigastric pain, and epigastric burning;

[0062] At least one of the above symptoms is met;

[0063] Course requirement: the symptoms have appeared for at least 6 months, and the above criteria are met in the last 3 months;

[0064] Exclusion criteria: no organic lesions such as peptic ulcer, gastric cancer, hepatobiliary and pancreatic diseases, etc. through gastroscopy, abdominal ultrasound, blood routine, liver and kidney function examination;

[0065] III. Administration method

[0066] The patients were randomly divided into 3 groups, 30 people in each group, and then the drugs in Example 5 and Comparative Examples 1-2 were given to each group of patients, 10 ml each time, 3 times a day, equivalent to 1.37 g of original medicinal materials per ml, for 4 consecutive weeks, and the patient conditions were observed.

[0067] IV. Efficacy evaluation standard

[0068] Mark the patient's symptoms in order of severity from mild to severe as 1, 2, 3, 4 points, count and record the symptom scores of the patients before and after treatment;

[0069] Mark the patient's symptoms in order of severity from mild to severe as 1, 2, 3, 4 points, count and record the symptom scores of the patients before and after treatment;

[0070] Mark the patient's symptoms in order of severity from mild to severe as 1, 2, 3, 4 points, count and record the symptom scores of the patients before and after treatment;

[0071] Mark the patient's symptoms in order of severity from mild to severe as 1, 2, 3, 4 points, count and record the symptom scores of the patients before and after treatment;

[0072] Mark the patient's symptoms in order of severity from mild to severe as 1, 2, 3, 4 points, count and record the symptom scores of the patients before and after treatment;

[0073] Mark the patient's symptoms in order of severity from mild to severe as 1, 2, 3, 4 points, count and record the symptom scores of the patients before and after treatment;

[0074] Mark the patient's symptoms in order of severity from mild to severe as 1, 2, 3, 4 points, count and record the symptom scores of the patients before and after treatment; Group Effective (person) Effective (person) Ineffective (person) Effective rate (%) Example 5 23 6 1 96.7% Comparative Example 1 8 6 16 46.7% Comparative Example 2 9 9 12 60.0% Mark the patient's symptoms in order of severity from mild to severe as 1, 2, 3, 4 points, count and record the symptom scores of the patients before and after treatment;

[0075] From the data in the above table, it can be seen that the number of patients with significant effect in the drug group of Example 5 is the largest, and the effective rate is as high as 96.7%. The number of patients with significant effect in the drug groups of Comparative Example 1 and Comparative Example 2 is less, and the effective rate is also lower than that of the drug group of Example 5. The possible reason is that after adjusting the prescription in Comparative Example 1 and Comparative Example 2, the relationship between the monarch, minister, assistant and envoy in the prescription changes, resulting in the disappearance of the complementary effect between the drugs, and further affecting the final treatment result.

Claims

1. A Chinese medicine composition for strengthening the spleen and promoting digestion, characterized in that: The invention comprises the following components in parts by weight: 45-75 parts of bupleurum chinense, 35-65 parts of white peony root, 35-65 parts of cinnamon twig, 120-180 parts of dried tangerine peel, 35-65 parts of pinellia tuber, 35-65 parts of atractylodes macrocephala, 35-65 parts of trichosanthes root, 45-85 parts of oriental rhizome, 35-65 parts of xi bai, 8-25 parts of rhubarb, 35-65 parts of immature bitter orange and 35-65 parts of zedoaria.

2. The Chinese medicine composition for strengthening the spleen and promoting digestion as claimed in claim 1, wherein The invention comprises the following components in parts by weight: 55-65 parts of bupleurum chinense, 45-55 parts of white peony root, 45-55 parts of cinnamon twig, 140-160 parts of dried tangerine peel, 45-55 parts of pinellia tuber, 45-55 parts of atractylodes macrocephala, 45-55 parts of trichosanthes root, 55-65 parts of oriental rhizome, 45-55 parts of scutellaria baicalensis, 10-20 parts of rhubarb, 45-55 parts of immature bitter orange and 45-55 parts of zedoaria.

3. The Chinese medicine composition for strengthening the spleen and promoting digestion as claimed in claim 1, wherein The invention comprises the following components in parts by weight: 65 parts of bupleurum root, 55 parts of white peony root, 55 parts of cinnamon twig, 160 parts of dried tangerine peel, 55 parts of pinellia tuber, 55 parts of atractylodes macrocephala, 55 parts of trichosanthes root, 65 parts of oriental rhizome, 55 parts of scutellaria baicalensis, 20 parts of rhubarb, 55 parts of immature bitter orange and 55 parts of zedoaria.

4. The Chinese medicine composition for strengthening the spleen and promoting digestion as claimed in claim 1, wherein The invention comprises the following components in parts by weight: 55 parts of bupleurum root, 45 parts of white peony root, 45 parts of cinnamon twig, 140 parts of dried tangerine peel, 45 parts of pinellia tuber, 45 parts of atractylodes macrocephala, 45 parts of trichosanthes root, 55 parts of oriental rhizome, 45 parts of scutellaria baicalensis, 10 parts of rhubarb, 45 parts of immature bitter orange and 45 parts of zedoaria.

5. The Chinese medicine composition for strengthening the spleen and promoting digestion as claimed in claim 1, wherein The invention comprises the following components in parts by weight: 60 parts of bupleurum root, 50 parts of white peony root, 50 parts of cinnamon twig, 150 parts of dried tangerine peel, 50 parts of pinellia tuber, 50 parts of atractylodes macrocephala, 50 parts of trichosanthes root, 60 parts of oriental rhizome, 50 parts of scutellaria baicalensis, 15 parts of rhubarb, 50 parts of immature bitter orange and 50 parts of zedoaria.

6. The Chinese medicine composition for strengthening the spleen and promoting digestion as claimed in claim 1, wherein The northern bupleurum is vinegar-cooked northern bupleurum, the white peony root is fried white peony root, the immature tangerine peel is fried immature tangerine peel with bran, the pinellia is ginger pinellia, the tangerine peel is fried tangerine peel with bran, the atractylodes is fried atractylodes with bran, the oriental radix is ​​salt oriental radix, and the zedoary turmeric is vinegar-cooked zedoary turmeric.

7. The method for preparing the spleen-strengthening and digestion-promoting Chinese medicine composition according to any one of claims 1 to 6, characterized in that: The following steps are involved: It is made by crushing and mixing the raw materials; or by extracting the raw materials by mixing or extracting them separately; or by further refining and purifying the extract to obtain the active ingredient; or by adding pharmaceutically acceptable excipients to the extract / active ingredient.

8. The method for preparing the spleen-strengthening and digestion-promoting Chinese medicine composition according to claim 7, wherein: The prepared dosage form is one of pills, granules, capsules, powders, mixtures, tablets, granules or oral liquids.

9. The method for preparing the spleen-strengthening and digestion-promoting Chinese medicine composition according to claim 7, wherein: The specific preparation method is as follows: add water to the above twelve ingredients and boil them, collect the filtrate and concentrate it to a relative density of 1.05-1.1, add auxiliary materials thereto, mix well, and then add purified water to make up the volume to obtain the product.

10. Use of the spleen-strengthening and digestion-promoting Chinese medicinal composition according to any one of claims 1 to 6 in the preparation of a spleen-strengthening and digestion-promoting medicine.