A new type of environmental protection material pipette tip leak detection device

Abstract

The application relates to the field of new material medical instrument detection, in particular to a pipette tip sealing property detection device of a new environment-friendly material. The pipette tip sealing property detection device comprises an injection unit, a tip limiting unit is arranged below the injection unit; the injection unit comprises an electric angular position table arranged in a lifting mode, a plurality of groups of injection heads for injecting non-transparent detection liquid are arranged on the output end of the electric angular position table in a horizontal direction at equal intervals; and the tip limiting unit comprises a bottom disc. The pipette tip sealing property detection device can fix the limiting ring by changing the clamping state of the spline clamping block and the spline clamping head, so that a pulling force is generated on the middle part of the tip when the tip swings, the whole tip is twisted, the types of external forces acting on the tip and the force-acting positions are changed, the detection strength is increased, the functionality of the device is enriched, the two detection modes can be switched simply and quickly, and the detection accuracy and authenticity are improved.

Description

Technical Field

[0001] This invention belongs to the field of new material medical device testing, and specifically relates to a novel environmentally friendly material pipette tip sealing test device. Background Technology

[0002] Compared to traditional pipette tips, more and more tips today are made from environmentally friendly new materials, namely conductive polypropylene. This material reduces sample adhesion to the pipette wall and is also easily degradable with minimal contamination. After the pipette tips are manufactured, they must first be tested for sealing to prevent sample leakage during use.

[0003] A search revealed the following patent document, CN221224549U, published on June 25, 2024, entitled "A Pipette Tip Detection Device." The document includes a base with a groove at its top containing a conveyor belt. A frame is fixedly mounted on one side of the base, and a feeding hopper is located within the frame. A discharging plate is located on the side wall of the feeding hopper, positioned above the base. A vibration assembly is located between the side of the frame away from the base and the side wall of the feeding hopper. The vibration assembly includes a support block fixedly mounted on the side wall of the feeding hopper. A first reduction motor is fixedly mounted on the side of the frame away from the base, and a support rod is fixedly mounted on the output shaft of the first reduction motor. The end of the support rod away from the first reduction motor rotates through the frame and is fixedly fitted with a cam, which contacts the side wall of the support block.

[0004] However, the above embodiments still have the following drawbacks:

[0005] The above embodiments cannot allow the suction head to be twisted or deformed, and can only perform detection in a static state. In other words, the above embodiments cannot simulate the actual degree of external force that the suction head will withstand during actual use. Not only is the detection function limited, but the accuracy of the detection is also reduced. Summary of the Invention

[0006] To address the aforementioned issues, this invention provides a novel environmentally friendly pipette tip sealing test device, comprising an injection unit, with a tip limiting unit located directly below the injection unit; the injection unit includes a liftable electric positioning stage, and several sets of injection tips for injecting non-transparent test liquids are arranged at equal intervals along the horizontal direction on the output end of the electric positioning stage.

[0007] The suction head limiting unit includes a chassis, and the top of the chassis has a number of crescent grooves arranged at equal intervals, the same number as the number of injection heads. Each crescent groove is slidably connected to a sliding limiting component for lifting the suction head from the bottom. A middle limiting ring is concentrically provided directly above the sliding limiting component, and an upper limiting ring is concentrically provided directly above the middle limiting ring.

[0008] Two sets of arc-shaped guide rails are symmetrically installed on the two side walls of the chassis. Side plates are slidably connected inside the arc-shaped guide rails. The tops of the two sets of side plates are fixedly connected to two sets of upper limit rings at the edges. A rotating shaft is fixedly connected between several sets of middle limit rings. The two ends of the rotating shaft are rotatably connected to the two sets of side plates, and one end passes through the side plate and is movably installed with a spline snap-fit ​​connector. A spline snap-fit ​​block is movably snapped onto the spline snap-fit ​​connector, and the spline snap-fit ​​block is in a fixed state.

[0009] Furthermore, a micro-injection pump is connected to the input end of the injection unit, a liquid storage tank is connected to the input end of the micro-injection pump, and a worktable is installed at the bottom of the suction tip limiting unit.

[0010] Furthermore, the worktable is symmetrically provided with a first mounting bracket and a second mounting bracket at the top edge of the outer walls on both sides perpendicular to the spline snap-fit ​​block. On the side wall of the first mounting bracket near the worktable, a number of infrared laser emitters are arranged at equal intervals in the horizontal direction, and the number of infrared laser emitters is the same as the number of injection heads.

[0011] Furthermore, a mapping whiteboard is mounted vertically on the top of the second mounting bracket. Several groups of photosensitive sensors, the same number as the number of infrared laser emitters, are arranged at equal intervals in the horizontal direction on the mapping whiteboard. Each group of photosensitive sensors is signal-connected to a corresponding group of infrared laser emitters.

[0012] Furthermore, the injection unit also includes a servo electric cylinder arranged in a vertical direction, with a lifting plate connected to the bottom of the servo electric cylinder. The electric angle positioning stage is installed at one edge of the bottom of the lifting plate, and a connecting plate is driven on the output end of the electric angle positioning stage. The end of the connecting plate away from the electric angle positioning stage extends horizontally to directly below the lifting plate, and several groups of injection heads are arranged at equal intervals on the connecting plate.

[0013] Furthermore, the top of the injection head is connected to a liquid inlet, and the input end of the liquid inlet is connected to the output end of the liquid storage tank through a set of flexible tubes; a sealing cap is fixedly sleeved on the outer wall of the injection head, and the central axis of the sealing cap coincides with the central axis of the injection head; the bottom height of the sealing cap is the same as the bottom height of the injection head.

[0014] Furthermore, a first plug is movably inserted into the arc guide rail, one end of which passes through the side plate and is inserted into the outer wall of the chassis.

[0015] A second plug is movably inserted into the spline snap-fit ​​block, and one end of the second plug is movably inserted into the side wall of the chassis.

[0016] Furthermore, the middle limiting ring includes a trumpet-shaped body, the top diameter of which is larger than the bottom diameter, and a first leakage hole is provided on the inner wall. A first anti-overflow ring is provided at the top opening of the trumpet-shaped body. A first liquid inlet tube is connected to one side edge of the bottom of the trumpet-shaped body. The first liquid inlet tube is connected to the liquid storage tank.

[0017] Furthermore, the sliding limiting component includes a slider that is slidably connected in the crescent groove. A tray is installed on the top of the slider, and a top groove with a hemispherical structure is opened on the top of the tray. Second seepage holes are evenly distributed on the inner wall of the top groove.

[0018] Furthermore, a second liquid inlet pipe is connected to one side edge of the bottom of the tray, and the second liquid inlet pipe is connected to the liquid storage tank; a second anti-overflow ring is installed at the top edge of the top groove.

[0019] The beneficial effects of this invention are:

[0020] 1. After placing the pipette tip with its opening facing upwards in the upper limit ring, the injection unit lowers to seal the pipette tip cavity and injects a non-transparent experimental liquid into the tip. Then, the electric angle stage drives the pipette tip to swing, simulating the pressure the tip experiences during actual use due to centrifugal force pulling and swinging. Simultaneously, simply engaging the spline locking block with the spline locking head secures the middle limit ring. This creates a pulling force on the middle part of the pipette tip during swinging, causing the tip to twist. This alters the type and location of the external force faced by the tip, increasing the detection power. This not only enriches the device's functionality but also allows for quick and easy switching between the two detection modes, improving detection accuracy and realism.

[0021] 2. During testing, an opaque experimental liquid is injected into each pipette tip using a micro-injection pump until the liquid level just covers the infrared laser emitter, blocking the infrared light and preventing the photosensor from capturing it. When a crack appears on the surface of the pipette tip, the internal experimental liquid leaks out, causing the liquid level to drop and allowing the photosensor to re-capture the red light emitted by the infrared laser emitter. The overall testing process is simple and easy to understand, facilitating observation and requiring minimal manual operation. This not only improves automation but also enhances the convenience of observing the test results.

[0022] 3. When a crack appears on the surface of the pipette tip, the experimental liquid seeps out. The experimental liquid in the upper part of the pipette tip flows into the trumpet-shaped body and then into the cavity of the trumpet-shaped body through the first seepage hole. It then returns to the storage tank through the first liquid inlet tube. The experimental liquid in the lower part of the pipette tip flows into the top groove, then into the cavity of the tray through the second seepage hole, and then returns to the storage tank through the second liquid inlet tube. This prevents the seeped liquid from flowing into the crescent groove below and onto the worktable, ensuring the cleanliness of the work surface and preventing waste of experimental liquid.

[0023] 4. A first anti-overflow ring and a second anti-overflow ring are respectively set at the four edges of the trumpet-shaped body and the top groove. This ensures that after the experimental liquid leaks out, it will be immediately intercepted by the first or second anti-overflow ring due to inertia and will not be thrown to the sides. This improves the collection effect of the experimental liquid and also enhances the auxiliary effect on the trumpet-shaped body and the top groove. Attached Figure Description

[0024] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0025] Figure 1 A schematic diagram of the detection device according to an embodiment of the present invention is shown;

[0026] Figure 2 A schematic diagram of the injection unit according to an embodiment of the present invention is shown;

[0027] Figure 3 A schematic diagram showing the connection between the injection head and the sealing cap according to an embodiment of the present invention is shown;

[0028] Figure 4 A schematic diagram of the structure of the worktable according to an embodiment of the present invention is shown;

[0029] Figure 5 A schematic diagram of the suction head limiting unit according to an embodiment of the present invention is shown;

[0030] Figure 6 A partially enlarged schematic diagram of a spline card connector according to an embodiment of the present invention is shown;

[0031] Figure 7 A schematic diagram of the suction head limiting unit for removing the spline clip connector according to an embodiment of the present invention is shown;

[0032] Figure 8A schematic diagram showing the positional relationship between the upper limit ring, the middle limit ring, and the sliding limit component according to an embodiment of the present invention is shown;

[0033] Figure 9 A schematic diagram of the structure of the middle limiting ring according to an embodiment of the present invention is shown;

[0034] Figure 10 An exploded view of a sliding limit component according to an embodiment of the present invention is shown.

[0035] In the diagram: 100, Detection frame; 200, Micro-injection pump; 300, Liquid reservoir; 400, Injection unit; 410, Servo cylinder; 420, Lifting plate; 430, Electric angle stage; 440, Connecting plate; 450, Injection head; 451, Liquid inlet; 460, Sealing cover; 500, Worktable; 510, First mounting bracket; 520, Second mounting bracket; 530, Mapping whiteboard; 540, Infrared laser emitter; 550, Clamping head support bracket; 560, Spline clamping head; 600, Suction tip limiting unit; 610. Chassis; 611, crescent groove; 620, curved guide rail; 621, first plug; 630, side plate; 640, spline snap block; 641, second plug; 650, upper limit ring; 651, sealing ring; 660, rotating shaft; 670, middle limit ring; 671, trumpet-shaped body; 672, first seepage hole; 673, first anti-overflow ring; 674, first liquid inlet tube; 680, sliding limit component; 681, slider; 682, tray; 683, top groove; 684, second seepage hole; 685, second anti-overflow ring. Detailed Implementation

[0036] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0037] This invention provides a novel pipette tip sealing performance testing device made of environmentally friendly materials. For example,... Figure 1 As shown, the device includes a testing frame 100, at the bottom of which is mounted a micro-injection pump 200. The micro-injection pump 200 is a Runze-SY08 brand. A reservoir 300 is located below the micro-injection pump 200, and the output end of the reservoir 300 is connected to the input end of the micro-injection pump 200 via a flexible tube.

[0038] The storage tank 300 contains non-transparent experimental liquids, including but not limited to colored pigments.

[0039] The micro-injection pump 200 has an injection unit 400 mounted on one side, which is raised and lowered. A worktable 500 is positioned directly below the injection unit 400, and a pipette tip limiting unit 600 is located on top of the worktable 500. The pipette tip is placed on the pipette tip limiting unit 600, and then the injection unit 400 injects the experimental liquid into the pipette tip, sealing the pipette tip cavity. The pipette tip is then driven to oscillate at a uniform speed. Simultaneously, the pipette tip limiting unit 600 can adjust the degree of deformation of the pipette tip during this uniform oscillation.

[0040] Specifically, the output end of the suction tip limiting unit 600 is connected to the input end of the liquid storage tank 300 via a flexible tube.

[0041] Specifically, the injection unit 400 is movably inserted into the suction head limiting unit 600.

[0042] For example, such as Figure 2 and Figure 3 As shown, the injection unit 400 includes a servo electric cylinder 410 arranged in a vertical direction. A lifting plate 420 is driven to the bottom of the servo electric cylinder 410. An electric angle stage 430 is installed at one edge of the bottom of the lifting plate 420. The electric angle stage 430 is a brand model LDD-BDWL-1204090L. A connecting plate 440 is driven to the output end of the electric angle stage 430. The end of the connecting plate 440 away from the electric angle stage 430 extends horizontally to directly below the lifting plate 420. Several sets of injection heads 450 are arranged at equal intervals on the connecting plate 440.

[0043] For example, the top of the injection head 450 is connected to a liquid inlet 451, and the input end of the liquid inlet 451 is connected to the output end of the liquid storage tank 300 through a set of flexible tubing. A sealing cap 460 is fixedly sleeved on the outer wall of the injection head 450 near the bottom, and the central axis of the sealing cap 460 coincides with the central axis of the injection head 450. The bottom height of the sealing cap 460 is the same as the bottom height of the injection head 450.

[0044] For example, such as Figure 4As shown, a first mounting bracket 510 and a second mounting bracket 520 are symmetrically arranged at the top edges of the outer walls on both sides of the worktable 500. On the side wall of the first mounting bracket 510 closest to the worktable 500, several groups of infrared laser emitters 540 are arranged at equal intervals along the horizontal direction. The number of infrared laser emitters 540 is the same as the number of injection heads 450. A mapping whiteboard 530 is vertically mounted on the top of the second mounting bracket 520. Several groups of photosensitive sensors, the same number as the infrared laser emitters 540, are arranged at equal intervals along the horizontal direction on the mapping whiteboard 530. Each group of photosensitive sensors is signal-connected to a corresponding group of infrared laser emitters 540.

[0045] During testing, a batch of pipette tips are first placed on the pipette tip limiting unit 600 with their openings facing upwards. Then, the servo cylinder 410 is activated, causing the lifting plate 420 and each group of injection heads 450 to descend until each group's sealing cap 460 engages with the top of the pipette tip limiting unit 600, completely sealing the pipette tip openings and ensuring the pipette tip cavity is sealed. Next, each group of infrared laser emitters 540 is activated. Since the pipette tips are transparent, the emitted infrared light is captured by the corresponding set of photosensitive sensors. Then, the micro-injection pump 200 is activated, simultaneously injecting the experimental liquid from the storage tank 300 into each group of pipette tips until the experimental liquid in the pipette tips just covers the height of the infrared laser emitters 540. Utilizing the opaque nature of the experimental liquid, the infrared light is blocked, preventing the photosensitive sensors from capturing it.

[0046] After injection, the motorized stage 430 is activated, causing each injection head to swing at a uniform speed. Because the sealed cover 460 is engaged with the pipette tip limiting unit 600, each pipette tip also swings along with the motorized stage 430. This shaking and pulling action tests the pipette tip's resilience, simulating the resistance it withstands under centrifugal force during real-world use. When cracks appear on the pipette tip surface due to this pulling, the internal experimental liquid leaks, causing the liquid level to drop. After the test, if the photosensitive sensor re-captures the red light emitted by the infrared laser emitter 540, it indicates a drop in liquid level and leakage. This is used to determine if the pipette tip fails to withstand external forces.

[0047] For example, a clamp support frame 550 is fixedly installed on the top edge of one side wall of the workbench 500 perpendicular to the first mounting frame 510, and a spline clamp 560 is movably installed on the clamp support frame 550, and the spline clamp 560 is movably engaged with the suction head limiting unit 600.

[0048] For example, such as Figure 5 , Figure 6 , Figure 7 and Figure 8 As shown, the suction head limiting unit 600 includes a chassis 610, which is movably mounted on the top of the worktable 500 and located directly below the injection unit 400. Several sets of crescent-shaped grooves 611 are arranged at equal intervals along the horizontal direction on the top of the chassis 610. The number of crescent-shaped grooves 611 is the same as that of the injection heads 450, and each set of crescent-shaped grooves 611 is located directly below a corresponding set of injection heads 450. The side view of each crescent-shaped groove 611 has a fan-shaped annular structure, and its extension path is perpendicular to the arrangement direction of each set of crescent-shaped grooves 611. A rotating shaft 660 is arranged horizontally above the chassis 610.

[0049] For example, a sliding limiting component 680 is slidably connected within the crescent groove 611. A middle limiting ring 670 is concentrically arranged directly above the sliding limiting component 680, and each set of middle limiting rings 670 is mounted on a rotating shaft 660. An upper limiting ring 650 is concentrically arranged directly above the middle limiting ring 670, and the diameter of the upper limiting ring 650 is larger than that of the middle limiting ring 670. Several sets of upper limiting rings 650 are fixedly connected to each other. The sealing cover 460 is movably attached to the top of the upper limiting ring 650, and a sealing ring 651 is provided at the joint between the two.

[0050] For example, two sets of curved guide rails 620 are symmetrically installed on the side walls of the chassis 610 near and away from the spline clamp head 560. The curvature of the curved guide rails 620 is the same as that of the crescent groove 611. Side plates 630 are slidably connected inside the curved guide rails 620. The tops of the two sets of side plates 630 extend vertically upward to the same height as the upper limit ring 650, and are fixedly connected to the two sets of upper limit rings 650 at the edges, respectively. A first plug 621 is movably inserted into the curved guide rail 620. One end of the first plug 621 passes through the side plate 630 and is inserted into the outer wall of the chassis 610.

[0051] For example, the two ends of the rotating shaft 660 are rotatably connected to two sets of side plates 630 respectively. The end of the rotating shaft 660 near the spline head 560 passes through the corresponding set of side plates 630 and is movably mounted with a spline locking block 640, which is movably locked with the spline head 560. A second plug 641 is movably inserted into the spline locking block 640, and one end of the second plug 641 is movably inserted into the side wall of the chassis 610.

[0052] For example, such as Figure 9As shown, the middle limiting ring 670 includes a trumpet-shaped body 671. The top diameter of the trumpet-shaped body 671 is larger than the bottom diameter, and a first leakage hole 672 is provided on the inner wall. A first anti-overflow ring 673 is provided at the top opening of the trumpet-shaped body 671. A first liquid inlet pipe 674 is connected to one edge of the bottom of the trumpet-shaped body 671. The first liquid inlet pipe 674 is connected to the liquid storage tank 300.

[0053] For example, such as Figure 10 As shown, the sliding limiting component 680 includes a slider 681, which is slidably connected within a crescent groove 611. A tray 682 is mounted on the top of the slider 681. The top of the tray 682 has a hemispherical top groove 683. Second leakage holes 684 are evenly distributed on the inner wall of the top groove 683. A second liquid inlet pipe is connected to one edge of the bottom of the tray 682, and the second liquid inlet pipe is connected to the storage tank 300. A second anti-overflow ring 685 is installed at the top edge of the top groove 683.

[0054] Before testing, first, position the nozzle opening upwards and insert it vertically through the upper limit ring 650 and the middle limit ring 670, finally positioning the bottom of the nozzle in the top groove 683. Then, pull out the first plug 621, allowing the side plate 630 to change angle with the chassis 610. For routine nozzle oscillation testing, simply remove the spline locking block 640. When the upper limit ring 650 engages with the sealing cover 460, the edge of the nozzle opening will abut against the inner wall of the sealing cover 460, sealing the nozzle cavity. At this point, activating the electric corner stage 430 will cause the nozzle to oscillate as a whole.

[0055] To change the detection force, first install the spline locking block 640 on the rotating shaft 660, then engage the spline locking block 640 with the spline locking head 560, and pull out the second pin 641. Since the rotating shaft 660 and the side plate 630 are rotatably connected, when the suction head swings, the engagement of the spline locking block 640 and the spline locking head 560 keeps the middle limit ring 670 in a fixed state. As the suction head swings, a pulling force is generated on the middle part of the suction head, causing the entire suction head to twist. This changes the type and location of the external force faced by the suction head, and also increases the detection force, making the detection more realistic.

[0056] The above embodiments have the following beneficial effects:

[0057] 1. After placing the pipette tip with its opening facing upwards in the upper limit ring 650, the injection unit 400 lowers as a whole to seal the pipette tip cavity and injects a non-transparent experimental liquid into the pipette tip. Then, the electric angle stage 430 drives the pipette tip to swing, simulating the degree of stress the pipette tip experiences during actual use due to centrifugal force pulling and swinging. Simultaneously, simply engaging the spline locking block 640 with the spline locking head 560 secures the middle limit ring 670. This creates a pulling force on the middle part of the pipette tip during swinging, causing the entire pipette tip to twist. This changes the type and location of the external force faced by the pipette tip, increasing the detection strength. This not only enriches the functionality of the device but also allows for quick and easy switching between the two detection modes, improving detection accuracy and realism.

[0058] 2. During testing, an opaque experimental liquid is injected into each set of pipette tips using a micro-injection pump 200 until the liquid level just covers the infrared laser emitter 540, blocking the infrared light and preventing the photosensitive sensor from capturing it. When a crack appears on the surface of the pipette tip, the internal experimental liquid leaks out, causing the liquid level to drop and allowing the photosensitive sensor to re-capture the red light emitted by the infrared laser emitter 540. The overall testing process is simple and easy to understand, facilitating observation and requiring minimal manual operation. This not only improves automation but also enhances the convenience of observing the test results.

[0059] 3. When a crack appears on the surface of the pipette tip, the experimental liquid seeps out. The experimental liquid in the upper part of the pipette tip flows into the trumpet-shaped body 671, and then into the cavity of the trumpet-shaped body 671 through the first seepage hole 672. It then returns to the storage tank 300 through the first liquid inlet tube 674. The experimental liquid in the lower part of the pipette tip flows into the top groove 683, then into the cavity of the tray 682 through the second seepage hole 684, and then returns to the storage tank 300 through the second liquid inlet tube. This prevents the seeped liquid from flowing onto the crescent groove 611 below and the worktable 500, ensuring the cleanliness of the worktable and preventing waste of the experimental liquid.

[0060] 4. A first anti-overflow ring 673 and a second anti-overflow ring 685 are respectively set at the four edges of the trumpet-shaped body 671 and the top groove 683. This ensures that after the experimental liquid leaks out, it will be immediately intercepted by the first anti-overflow ring 673 or the second anti-overflow ring 685 due to inertia and will not be thrown to the sides. This improves the collection effect of the experimental liquid and also enhances the auxiliary effect on the trumpet-shaped body 671 and the top groove 683.

[0061] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A novel environmental protection material pipette tip tightness detection device, characterized in that: The injection unit is provided with a suction head limiting unit below; the injection unit comprises an electric angular position table arranged in a lifting manner, and a plurality of groups of injection heads for injecting non-transparent detection liquid are arranged on the output end of the electric angular position table in a horizontal direction at equal intervals; The suction head limiting unit comprises a bottom disc, a plurality of groups of crescent grooves are arranged on the top of the bottom disc at equal intervals and in the same number as the injection heads, and a sliding limiting component for lifting the suction head from the bottom is slidably connected in each crescent groove; a middle limiting ring is concentrically arranged above the sliding limiting component, and an upper limiting ring is concentrically arranged above the middle limiting ring; Two groups of arc-shaped guide rails are symmetrically mounted on the side walls of the bottom disc, a side plate is slidably connected in each arc-shaped guide rail, and the top of each side plate is fixedly connected with two groups of upper limiting rings at the edges; a plurality of groups of middle limiting rings are fixedly connected between the middle limiting rings, and the two ends of a rotating shaft are rotatably connected with the two groups of side plates, one end of the rotating shaft penetrates through the side plate, and a spline connector is movably mounted on the end of the rotating shaft, a spline clamping block is movably clamped on the spline connector, and the spline clamping block is in a fixed state.

2. The pipette tip seal detection device of claim 1, wherein: A micro-injection pump is connected to the input end of the injection unit, a liquid storage tank is connected to the input end of the micro-injection pump, and a workbench is mounted at the bottom of the suction head limiting unit.

3. The pipette tip seal detection device of claim 2, wherein: First and second mounting racks are symmetrically arranged on the top edges of the two side walls of the spline clamping block perpendicular to the spline clamping block, a plurality of groups of infrared laser emitters are arranged on the side wall close to the workbench in a horizontal direction at equal intervals, and the number of the infrared laser emitters is the same as the number of the injection heads.

4. The pipette tip seal detection device of claim 3, wherein: A mapping whiteboard is mounted on the top of the second mounting rack in a vertical direction, a plurality of groups of photosensitive sensors are arranged on the mapping whiteboard in a horizontal direction at equal intervals and in the same number as the infrared laser emitters, and each group of photosensitive sensors is signal-connected with a corresponding group of infrared laser emitters.

5. The pipette tip seal detection device of claim 2, wherein: The injection unit further comprises a servo cylinder arranged in a vertical direction, a lifting plate is drivingly connected to the bottom of the servo cylinder, the electric angular position table is mounted at one side edge of the bottom of the lifting plate, a connecting plate is drivingly connected to the output end of the electric angular position table, the end of the connecting plate away from the electric angular position table extends to below the lifting plate in a horizontal direction, and a plurality of groups of injection heads are arranged on the connecting plate at equal intervals.

6. The pipette tip seal detection device of claim 5, wherein: An inlet is connected to the top of the injection head, the input end of the inlet is connected to the output end of the liquid storage tank through a group of hoses, a sealing upper cover is fixedly sleeved on the outer wall of the injection head, the central axis of the sealing upper cover coincides with the central axis of the injection head, and the height of the bottom of the sealing upper cover is the same as the height of the bottom of the injection head.

7. The pipette tip seal detection device of claim 1, wherein: A first plug is movably inserted into the arc-shaped guide rail, one end of the first plug penetrates through the side plate and is movably inserted into the outer wall of the bottom disc; A second plug is movably inserted into the spline clamping block, one end of the second plug is movably inserted into the side wall of the bottom disc.

8. The pipette tip seal detection device of claim 1, wherein: The middle limiting ring comprises a horn-shaped body, the diameter of the top of the horn-shaped body is larger than the diameter of the bottom, and a first liquid seepage hole is arranged on the inner wall of the horn-shaped body, and a first anti-overflow ring is arranged at the opening of the top of the horn-shaped body; a first liquid guide pipe is communicated with the horn-shaped body at one side edge of the bottom of the horn-shaped body; and the first liquid guide pipe is communicated with the liquid storage tank.

9. The pipette tip seal detection device of claim 1, wherein: The sliding limiting component comprises a sliding block, the sliding block is slidingly connected in the crescent-shaped groove, a tray is installed at the top of the sliding block, a top groove with a hemispherical structure is arranged at the top of the tray, and second liquid seepage holes are evenly distributed on the inner wall of the top groove.

10. The pipette tip seal integrity testing device of claim 9, wherein: A second liquid guide pipe is communicated with the tray at one side edge of the bottom of the tray, the second liquid guide pipe is communicated with the liquid storage tank, and a second anti-overflow ring is installed at the top edge of the top groove.

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