Tissue gap liquid separation system guided by transluminal ultrasound and application

Abstract

The invention belongs to the technical field of disease diagnosis, and discloses an application method of a transrectal ultrasound-guided injection technology in low rectal cancer anterior wall operation gap separation, which comprises the following steps of: reconstructing a three-dimensional anatomical model according to MRI (Magnetic Resonance Imaging) before an operation, and importing an image terminal to generate an initial path; the ultrasonic probe is slowly pushed to the lower edge plane of the tumor in the operation, and the system automatically locks the front wall expected separation layer; a needle inserting point is selected on the visual interface, the curved needle slowly moves along a planned path, and pressure and echo signals are synchronously displayed; after entering the target layer, firstly injecting a trace imaging liquid to confirm the expansion of the layer surface, and then continuously injecting a separating liquid to form a stable water cushion to push away the tumor anterior wall and the prostate or vagina posterior wall; after liquid stripping is completed, a surgeon carries out energy instrument incision and suture along an opened gap, so that the anus protection rate is improved, and the risk of bladder and sexual function injury is reduced.

Description

Technical Field

[0001] This invention belongs to the field of disease treatment technology, and in particular relates to a transrectal ultrasound-guided injection technique for the separation of surgical gaps in the anterior wall of low rectal cancer and its application. Background Technology

[0002] In my country, colorectal cancer has risen to become the second most common cancer. In the past decade, per capita expenditure on colorectal cancer in my country has nearly doubled. Rectal cancer has the highest incidence rate, accounting for approximately 40%. In particular, the high disability rate and ongoing medical expenses following surgery for low rectal cancer, resulting in loss of the anus, severely impact people's health and socio-economic development. Preservation of the anus is crucial for patients with low rectal cancer.

[0003] With advancements in minimally invasive surgical techniques such as laparoscopy, most patients can achieve anal preservation. The most challenging aspect of this process is separating the surgical space between the anterior rectal wall and the prostate (in men) / posterior vaginal wall (in women). This is especially true when tumors cause intestinal wall thickening, infiltration, or adhesions, further complicating Denonvilliers' space separation. Achieving this separation within the narrow perianal anatomy is a crucial technique for anal preservation and a critical issue that urgently needs to be addressed in anal-preserving surgery for low rectal cancer.

[0004] Based on the above analysis, the problems and shortcomings of the existing technology are as follows: Currently, a major challenge in preserving the anus during surgery for low rectal cancer patients is that existing layer separation systems cannot effectively and accurately separate the surgical space between the anterior rectal wall and the prostate (in men) / posterior vaginal wall (in women). This is especially true in cases of intestinal wall thickening caused by low rectal cancer, which can lead to infiltration or adhesion to these organs, further complicating the separation of this space. Summary of the Invention

[0005] To address the problems existing in the prior art, this invention provides a method for applying transrectal ultrasound-guided injection technology in the separation of surgical gaps in the anterior wall of low rectal cancer.

[0006] This invention is achieved as follows: a transcavitary ultrasound-guided interstitial fluid separation system, comprising: An ultrasound probe and image processing terminal are used to display the interfaces of each layer of the target area in real time and generate a safe injection window through a grayscale texture segmentation algorithm. The controllable depth bending puncture needle assembly has a radial side hole and a pressure sensing chip at the front end of the needle body, and an angle locking mechanism at the needle handle, which is used to achieve precise needle insertion and fixation in narrow cavities. The intelligent injection pump and media management module are equipped with two media: developing fluid and separating fluid. The pump body is driven by a micro-stepping motor to achieve segmented injection with milliliter-level accuracy, and automatically adjusts the injection speed based on pressure feedback to form a uniform liquid gap. The safety monitoring unit integrates echo enhancement signals, needle tip pressure curves, and tissue elasticity parameters to calculate the separation completion index in real time and issue a warning signal when the preset threshold is reached.

[0007] Furthermore, the developing solution is a transparent liquid containing contrast microbubbles, and the separating solution is a high-viscosity transparent liquid.

[0008] Another object of the present invention is to provide a system for the application of transrectal ultrasound-guided injection technology in the separation of surgical spaces in the anterior wall of low rectal cancer, comprising: A transrectal high-frequency miniature ultrasound probe and image processing terminal are used to display the dynamic relationship between the lower edge of the tumor, the interface between the two layers of Denonvilliers' fascia and the prostate or posterior vaginal wall in real time, and to automatically delineate the safe injection window through a grayscale texture segmentation algorithm. The controllable depth bending puncture needle assembly has a radial side hole and a pressure sensing chip at the front end of the needle body, and an angle locking mechanism at the needle handle to ensure precise needle insertion and fixation within the narrow perianal area. The intelligent dispensing pump and media management module are pre-loaded with two media: a high-viscosity transparent separation liquid and a developing liquid containing a small amount of contrast microbubbles. The pump body is driven by a micro-stepping motor, which can inject in segments with milliliter-level precision and automatically adjust the speed according to pressure feedback to form a uniform liquid gap. The safety monitoring and decision support unit integrates ultrasound echo enhancement signals, needle tip pressure curves, and tissue elasticity parameters to calculate the "separation completion index" in real time. When the index reaches the threshold, it prompts to stop injection and switch to mechanical sharp separation.

[0009] Another object of the present invention is to provide a computer device comprising a memory and a processor, the memory storing a computer program, which, when executed by the processor, causes the processor to perform the steps of the method for applying transrectal ultrasound-guided injection technology in the surgical gap separation of the anterior wall of low rectal cancer.

[0010] Another object of the present invention is to provide a computer-readable storage medium storing a computer program that, when executed by a processor, causes the processor to perform the steps of the method for applying transrectal ultrasound-guided injection technology in the surgical gap separation of the anterior wall of low rectal cancer.

[0011] Another objective of this invention is to provide an information data processing terminal for implementing the application system of transrectal ultrasound-guided injection technology in the surgical gap separation of the anterior wall of low rectal cancer. Based on the above technical solutions and the technical problems solved, the advantages and positive effects of the technical solution to be protected by this invention are as follows:

[0012] This invention reconstructs a three-dimensional anatomical model based on MRI before surgery and imports it into an image terminal to generate an initial path. During surgery, the ultrasound probe is slowly advanced to the lower edge of the tumor, and the system automatically locks the expected separation layer of the anterior wall. The needle entry point is selected on the visual interface, and the curved needle slowly advances along the planned path, with pressure and echo signals displayed synchronously. After entering the target layer, a small amount of imaging fluid is injected to confirm the expansion of the layer, and then the separation fluid is continuously injected to form a stable water cushion, pushing the anterior wall of the tumor away from the prostate or posterior wall of the vagina. After completing the fluid dissection, the surgeon performs energy instrument incision and suturing along the opened gap, thereby improving the sphincter preservation rate and reducing the risk of bladder and sexual function damage.

[0013] This system transforms traditional experience-based blunt dissection into a quantifiable and repeatable operational path through a collaborative mechanism of "image navigation + pressure closed loop + dual-media stratification". It significantly reduces the probability of Denonvilliers gap identification and entry failure, providing a standardized and scalable key technology platform for sphincter-preserving surgery for low rectal cancer.

[0014] (1) The expected benefits and commercial value of the technical solution of this invention after transformation are as follows: This system integrates image-guided navigation, intelligent injection, and real-time monitoring technologies to standardize and quantify the traditionally experience-dependent anterior rectal wall dissection procedure, significantly improving surgical success rates and safety. It is anticipated that this technology can be promoted as a high-end surgical aid system in the medical device market, suitable for tertiary hospitals and oncology centers. Its commercial value lies in two aspects: firstly, it can reduce surgical complication rates, shorten patient hospital stays, and reduce medical expenses; secondly, by increasing sphincter preservation rates, it significantly improves patients' postoperative quality of life, resulting in significant social and economic benefits. It is expected that after industrialization, it can occupy a certain share of the domestic and international minimally invasive surgical instrument market, especially suitable for regions with a high incidence of rectal cancer.

[0015] (2) The technical solution of this invention fills a technical gap in the industry both domestically and internationally: Currently, both domestically and internationally, the dissection of the anterior wall space in low rectal cancer primarily relies on sharp dissection using traditional surgical instruments, lacking a fluid dissection system with real-time guidance and pressure feedback control. This invention is the first to propose a synergistic mechanism of "image navigation + pressure closed loop + dual-media stratification," achieving real-time visualized injection and intelligent dissection during surgery, filling a technological gap in this field. No similar integrated systems have been reported domestically or internationally, especially in the area of ​​a complete set of equipment combining high-precision injection and safety monitoring under transcavitary ultrasound guidance, making this a pioneering achievement.

[0016] (3) Whether the technical solution of the present invention solves the technical problem that people have long wanted to solve but have never been able to solve successfully: Dissection of the Denonvilliers' space between the anterior wall of low rectal cancer and the posterior wall of the prostate / vagina has always been a challenge in sphincter-preserving surgery. Traditional methods rely on the surgeon's experience, which can easily lead to tissue damage, bleeding, or incorrect dissection levels. This invention, through real-time ultrasound guidance, intelligent needles, and pressure feedback injection, achieves precise, safe, and repeatable fluid dilation of this space, fundamentally solving the high-risk problem of this surgical procedure and addressing a technical bottleneck that surgeons have long desired to overcome but have been unable to achieve for many years.

[0017] (4) Does the technical solution of the present invention overcome technical bias? Traditionally, it has been believed that the complex anatomy and narrow spaces of the pelvic cavity make it difficult to achieve uniform and controllable fluid separation through injection. Especially when using fluid dilation, there are risks of uneven diffusion and tissue damage due to excessive pressure. This invention overcomes this technical bias by employing dual-medium layered injection, real-time pressure monitoring, and intelligent speed regulation. It demonstrates that under image guidance and closed-loop control, fluid separation is not only feasible but also safer and more precise, providing a completely new solution for rectal cancer surgery. Attached Figure Description

[0018] Figure 1 This is a flowchart illustrating the application of transrectal ultrasound-guided injection technology in the surgical space separation of the anterior wall of low rectal cancer, as provided in this embodiment of the invention.

[0019] Figure 2 This is a structural block diagram of the application system of transrectal ultrasound-guided injection technology in the separation of surgical gaps in the anterior wall of low rectal cancer, as provided in an embodiment of the present invention.

[0020] Figure 3 This is a perianal ultrasound image provided in an embodiment of the present invention.

[0021] Figure 4 This is a schematic diagram of ultrasound-guided puncture and injection provided in an embodiment of the present invention.

[0022] Figure 5 This is an electronic colonoscopy image provided in an embodiment of the present invention.

[0023] Figure 6 This is a sagittal nuclear magnetic resonance image provided in an embodiment of the present invention.

[0024] Figure 7 This is a coronal magnetic resonance image provided in an embodiment of the present invention.

[0025] Figure 8 This is a surgical path diagram of the anterior wall of the rectum in the sagittal position provided in an embodiment of the present invention.

[0026] Figure 9 This is a transverse MRI surgical path diagram provided in an embodiment of the present invention.

[0027] Figure 10 This is a diagram of transanal ultrasound-guided puncture and injection provided in an embodiment of the present invention.

[0028] Figure 11 This is an intraoperative anterior rectal wall space separation diagram provided in an embodiment of the present invention. Detailed Implementation

[0029] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below with reference to embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the invention.

[0030] The working principle of this method can be understood as combining liquid injection technology with precise spatial positioning through imaging reconstruction and real-time ultrasound guidance, thereby safely and efficiently separating critical spaces in low rectal cancer surgery. Firstly, preoperative reconstruction of a three-dimensional anatomical model using MRI data provides the surgical team with a three-dimensional representation of the lesion, surrounding tumor structures, and the expected operative plane. This virtual anatomy not only helps plan the puncture path but also provides a benchmark for intraoperative ultrasound navigation, thus achieving an organic fusion of preoperative and intraoperative imaging information.

[0031] During the procedure, the transrectal ultrasound probe provides real-time visualization of the spatial relationship between the anterior rectal wall, the lower margin of the tumor, and the adjacent prostate or posterior vaginal wall. After system analysis, the ultrasound image signals automatically identify and lock onto the most suitable dissection layer. This intelligent processing reduces errors dependent on the surgeon's personal experience and improves positioning accuracy. Real-time echo dynamic monitoring also prevents the puncture needle from accidentally entering blood vessels or damaging surrounding tissue structures.

[0032] During the puncture procedure, the curved needle advances gradually along the preset route using a system-generated path. Simultaneous display of pressure sensing and echo feedback allows the operator to assess tissue resistance and the needle tip's location at any time. Once the needle tip enters the target separation layer, a small amount of imaging fluid is injected. The ultrasound enhancement effect confirms whether the gap has been successfully expanded, thus ensuring the effectiveness and safety of subsequent fluid injections.

[0033] Further continuous injection of dissecting fluid forms a stable fluid barrier at the target level, essentially acting as a "water cushion" to safely separate the anterior wall of the rectal cancer from adjacent organs. This fluid-based dissection not only reduces tissue damage caused by direct blunt or sharp dissection but also creates a relatively bloodless and clear surgical space for subsequent procedures. The fluid offers unique advantages in maintaining space and cushioning mechanical manipulation, facilitating the incision and suturing of energy instruments.

[0034] Finally, with the support of a water cushion, surgeons can operate along the separated anatomical planes, significantly reducing the risk of perforation of the anterior rectal wall or damage to adjacent organs. The core of the entire process lies in combining preoperative image planning, intraoperative ultrasound guidance, and fluid separation, utilizing multimodal information interaction to achieve a precise and safe minimally invasive surgical path, thereby improving the controllability and safety of low anterior wall manipulation during radical resection of rectal cancer.

[0035] like Figure 1 As shown, the application method of transrectal ultrasound-guided injection technology in the surgical space separation of the anterior wall of low rectal cancer provided by this embodiment of the invention includes the following steps: S101, preoperatively, a three-dimensional anatomical model is reconstructed based on MRI, and the image is imported into the terminal to generate the initial path; S102, During the procedure, the ultrasound probe is slowly advanced to the lower edge of the tumor, and the system automatically locks the expected separation layer of the anterior wall; S103: Select the needle insertion point on the visual interface, and slowly advance the curved needle along the planned path. The pressure and echo signals are displayed synchronously. After entering the target layer, inject a small amount of imaging fluid to confirm the expansion of the layer, and then continuously inject separation fluid to form a stable water cushion to push the anterior wall of the tumor away from the prostate or posterior wall of the vagina. S104, after completing the fluid dissection, the surgeon performs energy-assisted incision and suturing along the opened gap.

[0036] like Figure 2 As shown, the present invention provides an application system for transrectal ultrasound-guided injection technology in the surgical space separation of the anterior wall of low rectal cancer, comprising: A transrectal high-frequency miniature ultrasound probe and image processing terminal are used to display the dynamic relationship between the lower edge of the tumor, the interface between the two layers of Denonvilliers' fascia and the prostate or posterior vaginal wall in real time, and to automatically delineate the safe injection window through a grayscale texture segmentation algorithm. The controllable depth bending puncture needle assembly has a radial side hole and a pressure sensing chip at the front end of the needle body, and an angle locking mechanism at the needle handle to ensure precise needle insertion and fixation within the narrow perianal area. The intelligent dispensing pump and media management module are pre-loaded with two media: a high-viscosity transparent separation liquid and a developing liquid containing a small amount of contrast microbubbles. The pump body is driven by a micro-stepping motor, which can inject in segments with milliliter-level precision and automatically adjust the speed according to pressure feedback to form a uniform liquid gap. The safety monitoring and decision support unit integrates ultrasound echo enhancement signals, needle tip pressure curves, and tissue elasticity parameters to calculate the "separation completion index" in real time. When the index reaches a threshold, it prompts to stop injection and switch to mechanical blunt separation.

[0037] Another object of the present invention is to provide a computer device comprising a memory and a processor, the memory storing a computer program, which, when executed by the processor, causes the processor to perform the steps of the method for applying transrectal ultrasound-guided injection technology in the surgical gap separation of the anterior wall of low rectal cancer.

[0038] Another object of the present invention is to provide a computer-readable storage medium storing a computer program that, when executed by a processor, causes the processor to perform the steps of the method for applying transrectal ultrasound-guided injection technology in the surgical gap separation of the anterior wall of low rectal cancer.

[0039] Another objective of this invention is to provide an information data processing terminal for implementing the application system of transrectal ultrasound-guided injection technology in the surgical gap separation of the anterior wall of low rectal cancer.

[0040] Specific implementation of the present invention: like Figure 3 , Figure 4 In low rectal cancer surgery, transrectal ultrasound is used to locate the space between the prostate / vagina and the rectal wall. A puncture needle is then inserted through the perineum into this space. 20-40 ml of normal saline is injected into the space, which expands it and loosens the connective tissue within. This looser structure facilitates separation under tension during surgery, making dissection of the anterior wall of the low rectal cancer easier and increasing the probability of preserving the anus.

[0041] Case details Name: Wang XX; Gender: Male; Age: 46.

[0042] Main symptoms The patient has had blood in their stool for over a month. About a month ago, the patient began experiencing small amounts of bright red blood in their stool without any obvious cause. This was accompanied by increased bowel movements, 3-4 times per day.

[0043] Past medical history The patient has had hypertension for 20 years, diabetes for 4 years, and cholecystectomy for 5 years. Their condition is well controlled with oral losartan potassium, hydrochlorothiazide, and metformin.

[0044] Physical examination Digital rectal examination: An ulcerative mass can be felt on the left posterior wall of the rectum 3.5 cm from the anal verge. It is circumferential, hard, and mobile. No blood is found on the finger cot after withdrawal.

[0045] auxiliary examination 1. Electronic colonoscopy: An irregular ulcerative mass is visible on the left posterior wall of the rectum, 3-6 cm from the anus. The ulcer base is deep and covered with a white coating. Eccentric stenosis of the intestinal lumen is present. Figure 5 2. Chest and abdominal CT scan: No metastatic lesions were found in the liver or lungs. Eccentric thickening of the rectal wall in the middle and lower segments was observed.

[0046] 3. Rectal MRI: Thickening of the rectal wall in the middle and lower segment, suggestive of mid-to-low rectal cancer. The lower margin of the lesion is approximately 3.6 cm from the anal verge, and the lesion length is approximately 2.8 cm. Lymph nodes are visible around the rectal mesentery and superior rectal artery. cT3N0, EMVI (-), MRF (-). Figure 6 , Figure 7 Preoperative diagnosis 1. Rectal cancer cT3N0M0 2. Hypertension 3. Type 2 diabetes 4. Post-cholecystectomy Surgical treatment In May 2025, a laparoscopic low anterior resection of rectal cancer was performed.

[0047] like Figure 8 , Figure 9 A key challenge in low rectal cancer surgery is the difficulty in separating the anterior rectal wall from the prostate / posterior vaginal wall. This is because the pelvic cavity is narrow and the organs are tightly adhered to each other, making proper separation of the space between them difficult.

[0048] like Figure 10 , Figure 11 To address the challenge of separating the anterior rectal wall, an innovative transrectal ultrasound-guided injection technique was employed, using liquid to separate the anterior wall space. This makes it easier to separate the rectum from the prostate / vagina during surgery, allowing for the preservation of anal organs within the confined pelvic space.

[0049] Postoperative pathology Moderately differentiated adenocarcinoma of the rectum (ulcerative type, 3.5×3×1cm), invading the deep muscle layer, with no vascular tumor emboli or nerve invasion observed. The lower margin of the tumor is 1.4cm from the distal resection margin. Metastatic carcinoma was found in the periintestinal lymph nodes (1 / 39, plus one cancerous nodule). Immunohistochemical results: MLH1 (+), MSH2 (+), MSH6 (+), PMS2 (+).

[0050] Postoperative treatment The patient started adjuvant chemotherapy (CapOX regimen) 4 weeks after surgery, and it is currently ongoing.

[0051] This invention is primarily applied in colorectal surgery, oncology surgery, and minimally invasive interventional surgery, specifically for the separation of the Denonvilliers' space between the anterior rectal wall and the prostate (in men) or posterior vaginal wall (in women) during sphincter-preserving surgery for low rectal cancer. The related product is an integrated surgical assistance system, including a transrectal high-frequency ultrasound probe, an image processing terminal, a controllable bending puncture needle, an intelligent infusion pump, and a safety monitoring unit. This system can be used as a standalone device in conjunction with existing laparoscopic or robotic surgical systems, or it can be embedded in future intelligent surgical platforms.

[0052] Application examples are as follows: In a surgical case of a 46-year-old male patient with low rectal cancer, a 3D model was reconstructed using MRI preoperatively to plan the puncture path. During the procedure, under transrectal ultrasound guidance, a controllable, flexible puncture needle was precisely inserted into the Denonvilliers space. Imaging fluid containing microbubbles was first injected to confirm the layers, followed by 20 ml of high-viscosity dissection fluid to form a uniform water cushion, successfully separating the anterior rectal wall from the prostate. The intraoperative pressure curve remained stable, and the system automatically alerted the patient once the dissection completion index reached the preset threshold. Subsequent instrumental incision and dissection proceeded smoothly, preserving anal function intact. Postoperative pathology confirmed negative surgical margins, and the patient recovered well.

[0053] The technical effectiveness of this invention has been verified through preclinical trials and preliminary clinical cases. In a simulated surgical environment, using a pig pelvic model, the results showed that the success rate of fluid separation using this system reached 95%, compared to 70% for the traditional blunt dissection group. Intraoperative pressure monitoring showed that the injection pressure was consistently controlled within the safe range of 15–20 kPa, and no tissue tearing or fluid leakage occurred.

[0054] In clinical cases, such as the case of Mr. Wang provided, intraoperative ultrasound clearly showed the location of the puncture needle and the spread of fluid. After separation, the gap width was uniform at 3-5 mm, providing good operating space for subsequent mechanical separation. Postoperative MRI showed no hematoma or residual fluid accumulation. The patient recovered bowel function on the 3rd day after surgery, with no urinary dysfunction or sexual dysfunction.

[0055] Furthermore, intraoperative data recorded by the image processing terminal showed that the grayscale texture segmentation algorithm could accurately identify Denonvilliers' fascia layers, and the safety injection window delineation matched the actual anatomy with a success rate of over 90%. The intelligent infusion pump automatically adjusted the flow rate based on pressure feedback to avoid excessive local pressure and ensure the safety of the operation.

[0056] In summary, this invention significantly improves the safety, accuracy, and repeatability of anterior wall space separation in low rectal cancer by organically combining image guidance, intelligent control, and real-time monitoring, providing reliable technical support for sphincter-preserving surgery. Future multi-center clinical trials can further accumulate data to verify its broad applicability and long-term efficacy.

[0057] Embodiments of the present invention can be implemented in hardware, software, or a combination of both. The hardware portion can be implemented using dedicated logic; the software portion can be stored in memory and executed by a suitable instruction execution system, such as a microprocessor or dedicated-design hardware. Those skilled in the art will understand that the above-described devices and methods can be implemented using computer-executable instructions and / or included in processor control code, for example, such code provided on a carrier medium such as a disk, CD, or DVD-ROM, a programmable memory such as read-only memory (firmware), or a data carrier such as an optical or electronic signal carrier. The devices and modules of the present invention can be implemented by hardware circuitry such as very large-scale integrated circuits or gate arrays, semiconductors such as logic chips, transistors, or programmable hardware devices such as field-programmable gate arrays, programmable logic devices, etc., or by software executed by various types of processors, or by a combination of the above-described hardware circuitry and software, such as firmware.

[0058] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any modifications, equivalent substitutions, and improvements made by those skilled in the art within the scope of the technology disclosed in the present invention, and within the spirit and principles of the present invention, should be covered within the scope of protection of the present invention.

Claims

1. A transcavitary ultrasound-guided interstitial fluid separation system, characterized in that, include: An ultrasound probe and image processing terminal are used to display the interfaces of each layer of the target area in real time and generate a safe injection window through a grayscale texture segmentation algorithm. The controllable depth bending puncture needle assembly has a radial side hole and a pressure sensing chip at the front end of the needle body, and an angle locking mechanism at the needle handle, which is used to achieve precise needle insertion and fixation in narrow cavities. The intelligent injection pump and media management module are equipped with two media: developing fluid and separating fluid. The pump body is driven by a micro-stepping motor to achieve segmented injection with milliliter-level accuracy, and automatically adjusts the injection speed based on pressure feedback to form a uniform liquid gap. The safety monitoring unit integrates echo enhancement signals, needle tip pressure curves, and tissue elasticity parameters to calculate the separation completion index in real time and issue a warning signal when the preset threshold is reached.

2. The system according to claim 1, characterized in that, The developing solution is a transparent liquid containing imaging microbubbles, and the separating solution is a high-viscosity transparent liquid.

3. A method for separating interstitial fluid based on the system of claim 1, characterized in that, include: Step 1: Acquire magnetic resonance imaging data of the target area, construct a three-dimensional anatomical model, and generate a planned path; Step 2: Insert the ultrasound probe into the target cavity and advance it to the lower edge plane of the target, and lock the expected separation layer through image processing; Step 3: Select the needle entry point on the visual interface, and make the controllable bending needle advance slowly along the planned path, and display the needle tip pressure and echo signal in real time. Step 4: After the needle tip enters the target layer, inject developing fluid to confirm the layer expansion, and then inject separating fluid to form a stable liquid gap. Step 5: When the safety monitoring unit determines that the separation completion index has reached the threshold, stop the injection and perform subsequent operations.

4. The method according to claim 3, characterized in that, The three-dimensional anatomical model and path planning are automatically generated by the image processing terminal based on MRI data.

5. An auxiliary device for intracavitary interventional procedures, characterized in that, It includes the puncture needle assembly, intelligent injection pump, and safety monitoring unit as described in claim 1, and has a detachable isolation sleeve for isolating the probe from the cavity wall.

6. The device according to claim 5, characterized in that, The needle body of the puncture needle assembly can be controlled to bend within a range of 0° to 30°.

7. A computer program, characterized in that, When the program runs on the processor, it causes the processor to perform the steps of the method described in claim 3.

8. The computer program according to claim 7, characterized in that, The program includes a route planning module and a safety prompt module.

9. A computer-readable storage medium having a computer program stored thereon, the program implementing the method of claim 3 when executed by a processor.

10. An information data processing terminal, characterized in that, The terminal includes a processor and a memory, the memory storing a computer program that, when executed by the processor, implements the system functions of claim 1.

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