Coating uniformity monitoring and feedback control method and system based on microwave signal

Abstract

The invention relates to the technical field of pharmaceutical coating methods, in particular to a coating uniformity monitoring and feedback control method and system based on microwave signals, and the method comprises the following steps: collecting microwave signals and moisture content values in the whole production process of N batches of historical pills, and building a microwave-moisture model; collecting a microwave signal of the pill in real time, and obtaining a real-time moisture content value of the pill based on the microwave signal and a microwave-moisture model; calculating an RSD (Relative Standard Deviation) value based on the plurality of moisture content values in a certain period, and automatically adjusting control parameters of the coating equipment according to the RSD value; and collecting the pills flowing out from the drying stage, and discharging the pills. According to the method, the completion opportunity of each production stage can be accurately determined based on the ideal moisture content of the pill, the uniformity of the coating process is further ensured through real-time calculation of the RSD value, compared with a traditional method, the method is more accurate in coating quality control, the rejection rate caused by insufficient uniformity is reduced, and the consistency and curative effect of drugs are improved.

Description

Technical Field

[0001] This invention relates to the field of pharmaceutical coating methods, and in particular to a method and system for monitoring and feedback control of coating uniformity based on microwave signals. Background Technology

[0002] In the pharmaceutical industry, coating is a crucial process in pill production, playing a vital role in ensuring product quality. The pill coating process typically involves a motor-driven rotating hopper to tumble the pills, allowing them to come into contact with atomized coating droplets and thus coat the pill's surface with the coating material. However, the natural dispersion caused by rolling cannot guarantee that every pill will receive a complete and uniform coating, resulting in incomplete coating and inconsistent coating quality.

[0003] To reduce the defect rate, existing technologies typically employ intermittent sampling and testing to assess coating uniformity, and then manually adjust the operating parameters of the coating equipment accordingly. This allows for precise processing of the pills at each stage of the production process. However, this feedback-based adjustment method, reliant on operator experience and subjective judgment, is inefficient and cannot accurately determine the completion time of each production stage. This not only increases pill production costs but also introduces uncertainty in drug output time, as well as fluctuations in drug production efficiency and product quality. Summary of the Invention

[0004] Therefore, the technical problem to be solved by the present invention is to overcome the problems of insufficient control of the uniformity of pill coating, lack of data support for adjusting operating parameters, and low production efficiency in the prior art.

[0005] To address the aforementioned technical problems, this invention provides a method for monitoring and feedback control of coating uniformity based on microwave signals, comprising the following steps:

[0006] S1: Collect microwave signals and moisture content values ​​throughout the entire production process of N batches of historical pills, and establish a microwave-moisture model;

[0007] S2: Real-time acquisition of microwave signals from the pills, and obtaining the real-time moisture content of the pills based on the microwave signals and the microwave-moisture model;

[0008] S3: Calculate the RSD value based on multiple moisture content values ​​within a certain period, and automatically adjust the control parameters of the coating equipment according to the RSD value, as follows:

[0009] Based on preset production node thresholds, different stages of the pill production process are determined. These production node thresholds include a first preset threshold, a second preset threshold, a third preset threshold, and a preset moisture threshold. When the pill is in the spray coating stage, it is determined whether the RSD value is less than the first preset threshold and greater than the second preset threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the spray coating stage continues. If yes, the pill enters the equilibrium stage. When the pill is in the equilibrium stage, it is determined whether the RSD value is less than the second preset threshold and greater than the third preset threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the equilibrium stage continues. If yes, the pill enters the drying stage. When the pill is in the drying stage, it is determined whether the RSD value is less than the third preset threshold and whether the real-time moisture content value is less than the preset moisture threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the drying stage continues. If yes, the pill flows out of the drying stage.

[0010] S4: Collect the pills flowing out from the drying stage and discharge the pills.

[0011] In one embodiment of the present invention, in S1, the method for establishing a microwave-moisture model includes: establishing a linear relationship between moisture content values ​​and microwave signals, and obtaining a fitting formula by fitting the microwave signals and moisture content values.

[0012] T n (x)=cos(n arccosx),|x|≤1

[0013] y = 6.4226 × 10 4 T0-85.0942Y1+0.0043Y2-7.1582×10 -8 T3

[0014] Where x is the microwave signal and y is the moisture content value.

[0015] In one embodiment of the present invention, in S1, microwave signals and moisture content values ​​of N batches of pills are collected throughout the entire production process using a microwave moisture meter, where N≥7.

[0016] In one embodiment of the present invention, in S2, the time intervals used to collect the microwave signal of the pill are: 2-5 s / time in the spray coating stage, 8-12 s / time in the balancing stage, and 3-6 s / time in the drying stage.

[0017] In one embodiment of the present invention, in S3, the microwave signal acquisition of each J pills is taken as a cycle, where J≥5.

[0018] In one embodiment of the present invention, in S3, the formula for calculating the RSD value is as follows:

[0019]

[0020]

[0021] in, x is the average value. i This represents the moisture content value.

[0022] In one embodiment of the present invention, the first preset threshold is set in the range of 9%-11%, the second preset threshold is set in the range of 4%-6%, the third preset threshold is set in the range of 2.5%-3.5%, and the preset moisture threshold is set in the range of 6%-8%.

[0023] This invention also provides a microwave signal-based coating uniformity monitoring and feedback control system, the system being used to implement the microwave signal-based coating uniformity monitoring and feedback control method, specifically including:

[0024] The model building module is used to collect microwave signals from the pills in real time and obtain the real-time moisture content of the pills based on the microwave signals and the microwave-moisture model.

[0025] The data acquisition module is used to acquire microwave signals from the pills in real time and obtain the real-time moisture content of the pills based on the microwave signals and the microwave-moisture model.

[0026] The feedback control module calculates the RSD value based on multiple moisture content values ​​within a certain period, and automatically adjusts the control parameters of the coating equipment according to the RSD value, as follows:

[0027] Based on preset production node thresholds, different stages of the pill production process are determined. These production node thresholds include a first preset threshold, a second preset threshold, a third preset threshold, and a preset moisture threshold. When the pill is in the spray coating stage, it is determined whether the RSD value is less than the first preset threshold and greater than the second preset threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the spray coating stage continues. If yes, the pill enters the equilibrium stage. When the pill is in the equilibrium stage, it is determined whether the RSD value is less than the second preset threshold and greater than the third preset threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the equilibrium stage continues. If yes, the pill enters the drying stage. When the pill is in the drying stage, it is determined whether the RSD value is less than the third preset threshold and whether the real-time moisture content value is less than the preset moisture threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the drying stage continues. If yes, the pill flows out of the drying stage.

[0028] The pill discharge module is used to collect the pills flowing out from the drying stage and discharge the pills.

[0029] The present invention also provides an electronic device, which includes a processor, a memory, and a bus system. The processor and the memory are connected through the bus system. The memory is used to store instructions, and the processor is used to execute the instructions stored in the memory to realize the coating uniformity monitoring and feedback control method based on microwave signals.

[0030] The present invention also provides a computer storage medium storing a computer software product, the computer software product including several instructions for causing a computer device to execute the microwave signal-based coating uniformity monitoring and feedback control method.

[0031] The present invention also provides a coating uniformity monitoring and feedback control device based on microwave signals, the device being used to implement the coating uniformity monitoring and feedback control system based on microwave signals.

[0032] Compared with the prior art, the above-described technical solution of the present invention has the following advantages:

[0033] First, this invention utilizes a microwave-moisture model to monitor the moisture content of pills in real time. By precisely adjusting the control parameters of the coating equipment, it accurately determines the completion time of each production stage based on the ideal moisture content achieved by the pills. Real-time calculation of the RSD value further ensures the uniformity of the coating process. Compared with traditional methods, this invention is more precise in coating quality control, reduces the scrap rate caused by insufficient uniformity, and improves the consistency and efficacy of the medicine.

[0034] Secondly, this invention reduces reliance on operator experience through real-time monitoring of microwave signals and automated feedback control, thereby reducing the time required for manual adjustments and potential human error. The automated control mechanism significantly improves production efficiency, achieving a more stable and predictable production process. At the same time, it reduces unnecessary material waste and production delays, thereby effectively reducing production costs and improving the economic benefits of the entire production process. Attached Figure Description

[0035] To make the content of this invention easier to understand, the invention will be further described in detail below with reference to specific embodiments and accompanying drawings, wherein...

[0036] Figure 1 This is a flowchart of the coating uniformity monitoring and feedback control method based on microwave signals according to the present invention;

[0037] Figure 2 This is a flowchart of S3 in the coating uniformity monitoring and feedback control method based on microwave signals of the present invention;

[0038] Figure 3 This is a graph showing the relationship between moisture content and microwave signal. Detailed Implementation

[0039] The present invention will be further described below with reference to the accompanying drawings and specific embodiments, so that those skilled in the art can better understand and implement the present invention. However, the embodiments described are not intended to limit the present invention.

[0040] Example 1

[0041] Reference Figure 1-2 As shown, this invention provides a method for monitoring and feedback control of coating uniformity based on microwave signals, comprising the following steps:

[0042] S1: Collect microwave signals and moisture content values ​​from the entire production process of N batches of historical pills to establish a microwave-moisture model;

[0043] S2: Real-time acquisition of microwave signals from the pills, and obtaining the real-time moisture content of the pills based on the microwave signals and the microwave-moisture model;

[0044] S3: Calculate the RSD value based on multiple moisture content values ​​within a certain period, and automatically adjust the control parameters of the coating equipment according to the RSD value, as follows:

[0045] Based on preset production node thresholds, different stages of the pill production process are determined. These production node thresholds include a first preset threshold, a second preset threshold, a third preset threshold, and a preset moisture threshold. When the pill is in the spray coating stage, it is determined whether the RSD value is less than the first preset threshold and greater than the second preset threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the spray coating stage continues. If yes, the pill enters the equilibrium stage. When the pill is in the equilibrium stage, it is determined whether the RSD value is less than the second preset threshold and greater than the third preset threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the equilibrium stage continues. If yes, the pill enters the drying stage. When the pill is in the drying stage, it is determined whether the RSD value is less than the third preset threshold and whether the real-time moisture content value is less than the preset moisture threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the drying stage continues. If yes, the pill flows out of the drying stage.

[0046] S4: Collect the pills flowing out from the drying stage and discharge the pills.

[0047] Specifically, in S1, a precise microwave-based moisture content prediction model is established based on microwave signals and moisture content values ​​from historical batch pill production processes. This data includes data from the spray coating stage, the balancing stage, and the drying stage, thus covering the variation range of the entire coating process. The established microwave-moisture model is obtained based on historical data using statistical methods (such as linear regression), providing a foundation for calculating real-time moisture content values ​​by measuring microwave signals in subsequent steps. In one specific implementation, a microwave moisture meter is used to collect microwave signals and moisture content values ​​from N batches of pills throughout the entire production process, where N ≥ 7.

[0048] The method for establishing the microwave-moisture model includes: establishing a linear relationship between moisture content values ​​and microwave signals, and obtaining a fitting formula by fitting the microwave signal and moisture content values.

[0049] T n (x)=cos(n arccosx),|x|≤1

[0050] y = 6.4226 × 10 4 T0-85.0942T1+0.0043T2-7.1582×10 -8 T3

[0051] Where x is the microwave signal and y is the moisture content value. Specifically, the moisture content value y of the pill can be calculated using the microwave signal value x through the above fitting formula, where T n (x) is the expression for a polynomial, n represents the order of the polynomial, x is the variable of the polynomial, and T0, T1, T2, and T3 represent the values ​​of the polynomial at different orders. 6.4226 × 10 4 85.0942 are the coefficients of T0, adjusting the effect of the 0th-order polynomial on y; 0.0043 are the coefficients of T1, adjusting the effect of the 1st-order polynomial on y; 7.1582 × 10⁻⁶ are the coefficients of T2, adjusting the effect of the 2nd-order polynomial on y. -8 These are the coefficients of T3, used to adjust the effect of the third-order polynomial on y.

[0052] In S2, a microwave-moisture model is used to instantly convert microwave signal measurements into moisture content values. This allows the system to obtain continuous or intermittent microwave signal data streams and their corresponding moisture content values ​​as needed via a microwave transmit-return device. Real-time and automatic monitoring improves data acquisition efficiency and makes the control process more precise. In one specific implementation, the time intervals for collecting microwave signals from the pills are: 2-5 seconds per time during the spray coating stage, 8-12 seconds per time during the balancing stage, and 3-6 seconds per time during the drying stage.

[0053] In S3, the uniformity of coating is characterized by the RSD (relative standard deviation) of moisture content values ​​over different time periods in the same medium.

[0054] The formula for calculating the RSD value is as follows:

[0055]

[0056]

[0057] in, Let m be the average value, n be the number of real-time moisture content values ​​collected within a certain period, and x be the index of the latest data point. i This represents the moisture content value. Specifically, The RSD (Relative Standard Deviation) represents the average moisture content of m data points over a certain period, used to describe the degree of variation in moisture content data. Furthermore, a lower RSD value indicates less variation in moisture content among different pills, suggesting more uniform coating, while a higher RSD value typically indicates uneven coating. The control parameters typically include rotation speed and spray pressure. Adjusting these parameters can affect the moisture content of the pill coating, thus influencing the RSD value. For example, when the RSD value is greater than a first preset threshold, increasing the rotation speed and spray pressure can decrease the RSD value until it falls within the range of less than the first preset threshold and greater than a second preset threshold. In some embodiments, the first preset threshold is set in the range of 9%-11%, the second preset threshold in the range of 4%-6%, the third preset threshold in the range of 2.5%-3.5%, and the preset moisture threshold in the range of 6%-8%.

[0058] In step S4, the pills flowing out of the drying stage are collected and discharged. Having undergone real-time monitoring and feedback control in the aforementioned steps, the pills flowing out of the drying stage have achieved good coating uniformity and meet the product discharge standards.

[0059] Example 2

[0060] This invention also provides a microwave signal-based coating uniformity monitoring and feedback control system, the system being used to implement the microwave signal-based coating uniformity monitoring and feedback control method, specifically including:

[0061] The model building module is used to collect microwave signals and moisture content values ​​throughout the entire production process of N batches of historical pills and establish a microwave-moisture model. The entire production process includes the spray coating stage, the equilibrium stage, and the drying stage.

[0062] The data acquisition module is used to acquire microwave signals from the pills in real time and obtain the real-time moisture content of the pills based on the microwave-moisture model.

[0063] The feedback control module is used to calculate the RSD value of the moisture content over a certain period in real time, and automatically adjust the control parameters of the coating equipment based on the RSD value, as follows:

[0064] Based on preset production node thresholds, different stages of the pill production process are determined. These production node thresholds include a first preset threshold, a second preset threshold, a third preset threshold, and a preset moisture threshold. Specifically, when the RSD value is higher than the first preset threshold, the pill undergoes a spray coating stage, and the control parameters are automatically adjusted to decrease the RSD value. When the RSD value is lower than the first preset threshold but higher than the second preset threshold, the pill undergoes a balancing stage, and the control parameters are automatically adjusted to bring the RSD value closer to the second preset threshold. When the RSD value is lower than the second preset threshold but higher than the third preset threshold, the pill undergoes a drying stage, and the control parameters are automatically adjusted to decrease the RSD value. When the RSD value is lower than the third preset threshold and the real-time moisture content is lower than the preset moisture threshold, the drying stage is considered complete.

[0065] The pill discharging module is used to discharge the pills after they have gone through the spray coating stage, the balancing stage, and the drying stage.

[0066] The following is a specific example: The sampling time is set to 10 seconds, which is the time for coating sampling; sampling is carried out at 11 sampling time points according to the coating drying time equipment, namely, after the coating liquid spraying ends, at 20 min, 40 min, 50 min, 60 min, 70 min, 75 min, 80 min, 85 min, 90 min, and before the exhaust is turned on; each sample is 20-30g, and the microwave signal data at the corresponding time point is recorded; 7 batches are tracked, and 2-3 batches are tracked for each batch.

[0067] The data from the seven batches were averaged at each collection time to obtain the moisture content values ​​corresponding to the 11 microwave signals as a reference. Figure 3 As shown.

[0068] A linear relationship was established between the moisture content value and the microwave signal. The microwave signal and moisture content were then fitted together to obtain the fitting formula:

[0069] T n (x)=cos(n arccosx),|x|≤1

[0070] y = 6.4226 × 10 4 T0-85.0942Y1+0.0043Y2-7.1582×10 -8 T3

[0071] Where x is the microwave signal and y is the moisture content value.

[0072] For unknown production batches, the moisture content can be determined by measuring microwave signals. The time interval for collecting microwave signals is set as follows: 2 seconds per measurement during the coating stage, 10 seconds per measurement during the equilibration stage, and 5 seconds per measurement during the drying stage. Each cycle consists of 5 measurements. The moisture RSD value for each cycle is calculated using the following formula:

[0073]

[0074]

[0075] in, x is the average value. i The moisture content value is used. When the calculated moisture content RSD is greater than 10%, the rotation speed and spray pressure are increased until 5% < RSD < 10%, indicating the end of the spray coating stage and the start of the equilibrium stage. The moisture content value is then calculated using real-time microwave signals to obtain the RSD value. When 3% < RSD < 5%, the coating result is stable, the equilibrium stage ends, and the drying stage begins. The moisture content value is then calculated using real-time microwave signals to obtain the RSD value. When the RSD value is less than 3% and the real-time moisture content value is less than 6.5%, the coating drying stage ends, and the material is discharged.

[0076] At this point, the unknown production batch of pills automatically ended the spray coating stage at 75 minutes and entered the balancing stage, automatically ended the balancing stage at 80 minutes and entered the drying stage, and automatically ended the drying stage at 88 minutes to be discharged.

[0077] Example 3

[0078] The present invention also provides an electronic device, which includes a processor, a memory, and a bus system. The processor and the memory are connected through the bus system. The memory is used to store instructions, and the processor is used to execute the instructions stored in the memory to realize the coating uniformity monitoring and feedback control method based on microwave signals.

[0079] Example 4

[0080] The present invention also provides a computer storage medium storing a computer software product, the computer software product including several instructions for causing a computer device to execute the microwave signal-based coating uniformity monitoring and feedback control method.

[0081] Example 5

[0082] The present invention also provides a coating uniformity monitoring and feedback control device based on microwave signals, the device being used to implement the coating uniformity monitoring and feedback control system based on microwave signals.

[0083] Those skilled in the art will understand that embodiments of this application can be provided as methods, systems, or computer program products. Therefore, this application can take the form of a completely hardware embodiment, a completely software embodiment, or an embodiment combining software and hardware aspects. Furthermore, this application can take the form of a computer program product embodied on one or more computer-usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) containing computer-usable program code.

[0084] This application is described with reference to flowchart illustrations and / or block diagrams of methods, apparatus (systems), and computer program products according to embodiments of this application. It will be understood that each block of the flowchart illustrations and / or block diagrams, and combinations of blocks in the flowchart illustrations and / or block diagrams, can be implemented by computer program instructions. These computer program instructions can be provided to a processor of a general-purpose computer, special-purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, generate instructions for implementing the flowchart... Figure 1 One or more processes and / or boxes Figure 1 A device that provides the functions specified in one or more boxes.

[0085] These computer program instructions may also be stored in a computer-readable storage medium that can direct a computer or other programmable data processing device to function in a particular manner, such that the instructions stored in the computer-readable storage medium produce an article of manufacture including instruction means, which are implemented in a process Figure 1 One or more processes and / or boxes Figure 1 The function specified in one or more boxes.

[0086] These computer program instructions may also be loaded onto a computer or other programmable data processing equipment to cause a series of operational steps to be performed on the computer or other programmable equipment to produce a computer-implemented process, thereby providing instructions that execute on the computer or other programmable equipment for implementing the process. Figure 1 One or more processes and / or boxes Figure 1 The steps of the function specified in one or more boxes.

[0087] Obviously, the above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation. Those skilled in the art will recognize that other variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. However, obvious variations or modifications derived therefrom are still within the scope of protection of this invention.

Claims

1. A method for monitoring and feedback control of coating uniformity based on microwave signals, characterized in that, Includes the following steps: S1: Collect microwave signals and moisture content values ​​from the entire production process of N batches of historical pills to establish a microwave-moisture model; S2: Real-time acquisition of microwave signals from the pills, and obtaining the real-time moisture content of the pills based on the microwave signals and the microwave-moisture model; S3: Calculate the RSD value based on multiple moisture content values ​​within a certain period, and automatically adjust the control parameters of the coating equipment according to the RSD value, as follows: Based on preset production node thresholds, different stages of the pill production process are determined. The production node thresholds include a first preset threshold, a second preset threshold, a third preset threshold, and a preset moisture threshold. When the pill is in the spray coating stage, it is determined whether the RSD value is less than the first preset threshold and greater than the second preset threshold. If not, the control parameters are automatically adjusted to change the RSD value and the spray coating stage continues. If yes, the pill enters the balancing stage. When the pill is in the balancing stage, it is determined whether the RSD value is less than the second preset threshold and greater than the third preset threshold. If not, the control parameters are automatically adjusted to change the RSD value and the balancing stage continues. If yes, the pill enters the drying stage. When the pill is in the drying stage, it is determined whether the RSD value is less than the third preset threshold and whether the real-time moisture content value is less than the preset moisture threshold. If not, the control parameters are automatically adjusted to change the RSD value and the drying stage continues. If yes, the pill flows out of the drying stage. S4: Collect the pills flowing out from the drying stage and discharge the pills.

2. The method for monitoring and feedback control of coating uniformity based on microwave signals according to claim 1, characterized in that, In S1, the method for establishing the microwave-moisture model includes: establishing a linear relationship between moisture content values ​​and microwave signals, and obtaining a fitting formula by fitting the microwave signals and moisture content values. T n (x)=cos(n arccosx),|x|≤1 y=6.4226×10 4 T0-85.0942T1+0.0043T2-7.1582×10 -8 T3 Where x is the microwave signal and y is the moisture content value.

3. The method for monitoring and feedback control of coating uniformity based on microwave signals according to claim 1, characterized in that, In S1, microwave signals and moisture content values ​​of N batches of pills are collected throughout the entire production process using a microwave moisture meter, where N≥7.

4. The method for monitoring and feedback control of coating uniformity based on microwave signals according to claim 1, characterized in that, In S2, the time intervals for collecting microwave signals from the pills are: 2-5 seconds per time during the spray coating stage, 8-12 seconds per time during the balancing stage, and 3-6 seconds per time during the drying stage.

5. The method for monitoring and feedback control of coating uniformity based on microwave signals according to claim 1, characterized in that, In S3, the formula for calculating the RSD value is as follows: in, x is the average value. i This represents the moisture content value.

6. The method for monitoring and feedback control of coating uniformity based on microwave signals according to claim 1, characterized in that, The first preset threshold is set within the range of 9%-11%, the second preset threshold is set within the range of 4%-6%, the third preset threshold is set within the range of 2.5%-3.5%, and the preset moisture threshold is set within the range of 6%-8%.

7. A coating uniformity monitoring and feedback control system based on microwave signals, characterized in that, The system is used to implement the coating uniformity monitoring and feedback control method based on microwave signals as described in any one of claims 1-6, specifically including: The model building module is used to collect microwave signals from the pills in real time and obtain the real-time moisture content of the pills based on the microwave signals and the microwave-moisture model. The data acquisition module is used to acquire microwave signals from the pills in real time and obtain the real-time moisture content of the pills based on the microwave signals and the microwave-moisture model. The feedback control module calculates the RSD value based on multiple moisture content values ​​within a certain period, and automatically adjusts the control parameters of the coating equipment according to the RSD value, as follows: Based on preset production node thresholds, different stages of the pill production process are determined. These thresholds include a first preset threshold, a second preset threshold, a third preset threshold, and a preset moisture threshold. When the pill is in the spray coating stage, it is determined whether the RSD value is less than the first preset threshold and greater than the second preset threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the spray coating stage continues. If yes, the pill enters the equilibrium stage. When the pill is in the equilibrium stage, it is determined whether the RSD value is less than the second preset threshold and greater than the third preset threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the equilibrium stage continues. If yes, the pill enters the drying stage. When the pill is in the drying stage, it is determined whether the RSD value is less than the third preset threshold and whether the real-time moisture content is less than the preset moisture threshold. If not, the control parameters are automatically adjusted to change the RSD value, and the drying stage continues. If yes, the pill flows out of the drying stage. The pill discharge module is used to collect the pills flowing out from the drying stage and discharge the pills.

8. An electronic device, characterized in that, The electronic device includes a processor, a memory, and a bus system. The processor and the memory are connected through the bus system. The memory is used to store instructions, and the processor is used to execute the instructions stored in the memory to implement the coating uniformity monitoring and feedback control method based on microwave signals as described in any one of claims 1 to 6.

9. A computer storage medium, characterized in that, The computer storage medium stores a computer software product, which includes several instructions for causing a computer device to execute the coating uniformity monitoring and feedback control method based on microwave signals as described in any one of claims 1 to 6.

10. A coating uniformity monitoring and feedback control device based on microwave signals, characterized in that, The device is used to implement the microwave signal-based coating uniformity monitoring and feedback control system as described in claim 7.

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