Self-discharging assembly and ureteral stent

Abstract

The invention discloses a self-discharging assembly and a ureteral stent, and relates to the technical field of medical instruments. The self-discharging assembly comprises a self-discharging wire, a degradable fixing part and a self-discharging body, the self-discharging wire is provided with a first fixing end and a second fixing end, the first fixing end is used for being fixedly connected with a ureteral stent, and the second fixing end is used for being fixedly connected with the self-discharging body; at least part of the self-arranging wire between the first fixing end and the second fixing end is wound on the ureteral stent, and the self-arranging wire and the ureteral stent can be fixed in a falling-off mode through the degradable fixing part. According to the self-arranging assembly, the self-arranging wire and the self-arranging body can be limited in the body, the technical problems that the infection risk is high due to the fact that the self-arranging wire is left in vitro, the ureteral stent is displaced due to accidental traction of the self-arranging wire, and complications are likely to be caused can be solved, and the hidden danger that the self-arranging wire is wound and knotted or wound and knotted with the ureteral stent can be reduced.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a self-exhausting component and a ureteral stent. Background Technology

[0002] Indwelling ureteral stent placement (commonly known as DJ stent, double-J stent, or pigtail stent) is a common procedure in urology, used to treat ureteral obstruction and aid recovery after urinary tract stone surgery. Traditionally, indwelling ureteral stents require urethrocystoscopy for removal, which often results in complications such as urethral pain, gross hematuria, urethral injury, bladder irritation, urinary tract infection, and fever.

[0003] Developing ureteral stent removal methods that do not require cystoscopy has become an urgent technical problem to be solved in urology. Three main development trends exist in this field: biodegradable ureteral stents, magnetic ureteral stents, and ureteral stents with tail wires. However, all three methods have drawbacks.

[0004] Biodegradable ureteral stents are still in the conceptual stage, and there are still many problems to be solved, such as insufficient degradation, mechanical maintenance, and biocompatibility.

[0005] Magnetic ureteral stents are operated blindly because the two magnets attract each other in the bladder, making it difficult to determine whether the operation is successful. This may require repeated insertion of the removal device into the urethra, which to some extent increases the damage to the urethra. Due to the limited magnetic force of the magnetic tube removal, especially in special cases such as benign prostatic hyperplasia or urethral stricture, it is not easy to attract and remove the ureteral stent.

[0006] Ureteral stents with tail sutures are only suitable for patients with short-term indwelling ureteral stents because the tail suture can become a channel for bacterial colonization. Studies have shown that the risk of retrograde infection increases from 8% to 42%. In addition, ureteral stents with tail sutures have a greater risk of stent displacement due to accidental traction on the tail suture, requiring emergency surgery for repositioning. If the tail suture is left in the urethra for a long time, especially in men where the urethra is long and curved, friction can easily lead to related complications such as acute urethral syndrome and urethritis.

[0007] Therefore, there is an urgent need to improve existing self-draining ureteral stents and provide a ureteral stent that can leave the tail wire inside the body, which has become a technical problem that needs to be solved by those skilled in the art. Summary of the Invention

[0008] This invention discloses a self-exhausting component and a ureteral stent to solve the technical problems of ureteral stents with tail threads in related technologies, where the tail thread is left outside the body, resulting in a high risk of infection, accidental traction of the tail thread leading to stent displacement, and easy occurrence of complications.

[0009] To solve the above problems, the present invention adopts the following technical solution: The first aspect of the present invention discloses a self-dispatch assembly.

[0010] The self-draining assembly of the present invention is used in a ureteral stent. The self-draining assembly includes a self-draining wire, a biodegradable fixing part, and a self-draining body. The self-draining wire has a first fixing end and a second fixing end. The first fixing end is used to be fixedly connected to the ureteral stent, and the second fixing end is used to be fixedly connected to the self-draining body. The self-draining wire between the first fixing end and the second fixing end is at least partially coiled around the ureteral stent, and the biodegradable fixing part allows the self-draining wire to be detachably fixed to the ureteral stent.

[0011] According to an alternative embodiment, for a double J-type ureteral stent, the highest point of the self-draining line is located above the highest point of the second hook of the ureteral stent, and the self-draining line is at least partially located within the ureter.

[0012] According to an alternative embodiment, the length of the self-draining cord wound around the ureteral stent satisfies the following condition: for a double-J ureteral stent, the center of the self-draining body is lower than the lowest point of the bladder end hook of the ureteral stent.

[0013] According to one alternative embodiment, the distance between the self-exhausting body and the lowest point of the bladder end hook of the ureteral stent is 10~60mm.

[0014] According to an alternative embodiment, the length of the self-draining line is greater than 35 cm, and at least 50% of the length of the self-draining line is located above the highest point of the second hook of the ureteral stent.

[0015] According to one alternative embodiment, the self-draining cable is coiled on the outer or inner wall of the ureteral stent.

[0016] According to one alternative implementation, when the self-draining cable is coiled around the ureteral stent, the self-draining cable at the inflection point has a first arc-shaped structure.

[0017] According to one alternative embodiment, the self-draining line located in the curved section of the ureteral stent has a second arcuate structure along the shape of the ureteral stent.

[0018] According to one alternative embodiment, the portion of the self-draining cable wound around the ureteral stent is U-shaped, Z-shaped, or X-shaped.

[0019] According to one alternative implementation, the self-aligning line is a monofilament.

[0020] According to an optional embodiment, the self-layout line is a multifilament, the fineness of the multifilament is not less than 10D, and / or the self-layout line is also provided with a plurality of anti-tangle points at intervals, and / or the surface of the self-layout line is provided with an antibacterial coating; and / or the surface of the self-layout line is provided with an anti-shelling coating.

[0021] According to an optional embodiment, there are multiple biodegradable fixing parts, and the biodegradable fixing parts are spaced apart on the self-draining line.

[0022] According to one alternative embodiment, the biodegradable fixing part is located at the inflection point of the self-draining cable.

[0023] According to one alternative embodiment, the biodegradable fixing part is one or more of the following: sleeve, heat shrink tubing, coating, and knot.

[0024] According to an optional embodiment, the ureteral stent is provided with a first through hole, the first fixed end passes through the first through hole, the connection between the first fixed end and the first through hole forms a fixed connection point, and the self-draining line near the first fixed end faces the end of the ureteral stent.

[0025] According to an optional embodiment, the first fixing end is wound around the end of the ureteral stent, a fixing connection point is formed at the starting point of the winding of the first fixing end, the fixing connection point is 1~3mm away from the end of the ureteral stent, and the self-draining line near the first fixing end is directed toward the end of the ureteral stent.

[0026] According to one optional implementation, the number of self-discharging bodies is at least one; when the number of self-discharging bodies is two or more, the self-discharging bodies are spaced apart.

[0027] According to one alternative embodiment, the self-draining body has a structure with rounded edges.

[0028] According to one alternative implementation, the maximum size of the self-discharging body is 1~2 mm.

[0029] According to one alternative embodiment, the self-draining body is made of a material with a density greater than that of water, or the self-draining body is made of a highly absorbent material.

[0030] According to an optional embodiment, the self-draining body is provided with a second through hole, and the second fixed end passes through the second through hole.

[0031] According to one optional embodiment, the self-draining body and the second fixed end are fixedly connected by adhesive bonding.

[0032] According to one alternative embodiment, the second fixed end is wound around the self-discharging body to achieve a fixed connection.

[0033] A second aspect of the present invention discloses a ureteral stent.

[0034] The ureteral stent of the present invention includes a stent body and a self-draining component, wherein the self-draining component is the self-draining component described in any of the technical solutions of the present invention, and the self-draining component is disposed on the stent body.

[0035] The technical solution adopted in this invention can achieve the following beneficial effects: In a first aspect, when the self-draining assembly of the present invention is used for a ureteral stent, both ends of the self-draining wire are fixedly connected to the ureteral stent and the self-draining body, respectively. The self-draining wire is at least partially coiled around the ureteral stent, and the self-draining wire and the ureteral stent are detachably fixed by a biodegradable fixing part. This allows the self-draining wire and the self-draining body of the self-draining assembly to be confined within the body, avoiding the technical problems of high infection risk caused by the self-draining wire remaining outside the body, accidental traction of the self-draining wire leading to displacement of the ureteral stent, and easy occurrence of complications.

[0036] Furthermore, the self-draining suture of the present invention is at least partially coiled around the ureteral stent, which allows at least part of the suture to remain inside the ureter. The suture can only be discharged after the edema at the junction of the bladder and ureter has completely subsided, which can improve the patient's experience and the safety of ureteral stent discharge. On the other hand, the fact that at least part of the suture remains inside the ureter can reduce irritation to the bladder and relieve symptoms such as urinary frequency.

[0037] Secondly, in the self-draining assembly of the present invention, the self-draining cord is at least partially coiled around the ureteral stent, resulting in a shorter length of the movable portion of the self-draining cord within the bladder. This reduces the risk of the self-draining cord becoming entangled or knotted with the ureteral stent. Specifically, the shorter length of the movable portion of the self-draining cord reduces the probability of it becoming entangled or knotted with the ureteral stent. Furthermore, the shorter length of the movable portion of the self-draining cord also means a shorter portion of the cord being twisted by external forces within the bladder cavity, further reducing the risk of the self-draining cord becoming entangled or knotted with the ureteral stent within the bladder, thus improving the reliability of the ureteral stent's self-draining.

[0038] Thirdly, in the self-draining assembly of the present invention, the self-draining cord is at least partially coiled around the ureteral stent. This method, due to the relatively long connecting portion of the ureteral stent, reduces the number of folds in the self-draining cord, thereby reducing the risk of cord bending. Alternatively, when the self-draining cord is coiled around the ureteral stent, the bending angle at the inflection point can be less than 180°, further reducing the risk of bending at the inflection point. Therefore, since the self-draining cord of the present invention is at least partially coiled around the ureteral stent, the self-draining cord is easily straightened when subjected to the action of the self-draining body, thereby further improving the reliability of ureteral stent discharge. Attached Figure Description

[0039] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0040] Figure 1 This is a schematic diagram of the support body according to an embodiment of this application; Figure 2 This is a schematic diagram of the ureteral stent according to the first embodiment of this application; Figure 3 This is a schematic diagram of the ureteral stent according to the second embodiment of this application; Figure 4 This is a schematic diagram of the ureteral stent according to the third embodiment of this application; Figure 5 This is a schematic diagram of the ureteral stent according to the fourth embodiment of this application; Figure 6 This is a partial schematic diagram of the ureteral stent according to the fifth embodiment of this application; Figure 7 This is a partial schematic diagram of the ureteral stent according to the sixth embodiment of this application; Figure 8 This is a schematic diagram of the self-wiring system according to an embodiment of this application; Figure 9 This is a schematic diagram of another embodiment of the self-wiring system in this application; Figure 10 This is a schematic diagram of the self-discharging body according to an embodiment of this application; Figure 11 This is a schematic diagram of the fixed connection between the self-unloading cable and the self-unloading body in an embodiment of this application; Figure 12 This is a schematic diagram of another embodiment of the present application showing the self-connecting cable and the self-connecting body fixedly connected.

[0041] In the diagram: 110, self-draining cable; 111, first fixed end; 112, second fixed end; 113, first arc-shaped structure; 114, second arc-shaped structure; 120, biodegradable fixing part; 130, self-draining body; 131, second through hole; 140, anti-tangle point; 150, fixing connection point; 200, ureteral stent; 210, stent body; 211, first through hole; 212, first hook; 213, second hook; 214, connecting part. Detailed Implementation

[0042] To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions of this invention will be described in detail below. Obviously, the described embodiments are merely some embodiments of this invention, and not all embodiments. Based on the embodiments of this invention, all other implementation methods obtained by those skilled in the art without creative effort are within the scope of protection of this invention.

[0043] The terms "first," "second," etc., used in the specification and claims of this application are used to distinguish similar objects and not to describe a specific order or sequence. It should be understood that such use of data can be interchanged where appropriate so that embodiments of this application can be implemented in orders other than those illustrated or described herein, and the objects distinguished by "first," "second," etc., are generally of the same class and the number of objects is not limited; for example, a first object can be one or more. Furthermore, in the specification and claims, "and / or" indicates at least one of the connected objects, and the character " / " generally indicates that the preceding and following objects are in an "or" relationship.

[0044] In related technologies, ureteral stents with tail threads typically leave the tail thread outside the body, leading to an increased risk of infection. Because the tail thread can become a pathway for bacterial colonization, research data shows that the risk of retrograde infection increases from 8% to 42%. In addition, ureteral stents with tail threads have a greater risk of stent displacement due to accidental traction on the tail thread, requiring emergency surgery for repositioning. If the tail thread remains in the urethra for a long time, especially in men where the urethra is long and curved, friction can easily lead to related complications such as acute urethral syndrome and urethritis.

[0045] Therefore, this application provides a self-draining assembly, which includes a self-draining thread, a biodegradable fixing part, and a self-draining body. Based on a ureteral stent, the self-draining thread is at least partially coiled around the ureteral stent, and the biodegradable fixing part allows the self-draining thread to be detachably fixed to the ureteral stent. This method not only restricts the self-draining thread and self-draining body of the self-draining assembly to the body, avoiding the technical problems of high infection risk caused by the self-draining thread remaining outside the body, accidental traction of the self-draining thread leading to ureteral stent displacement, and easy occurrence of complications, but also reduces the risk of the self-draining thread itself getting tangled or knotted with the ureteral stent, thereby improving the reliability of the ureteral stent self-draining.

[0046] The following is in conjunction with the appendix Figures 1 to 12 The self-exhausting component and ureteral stent provided in this application will be described in detail through specific embodiments and application scenarios.

[0047] The self-draining component of this embodiment is used in the ureteral stent 200. The ureteral stent 200 includes a stent body 210, as shown below. Figure 1 As shown. The support body 210 is provided with a first through hole 211, which is used for drainage, as shown. Figure 1 As shown. The renal pelvic end of the stent body 210 has a first hook 212, and the bladder end of the stent body 210 has a retaining portion to fix the stent body 210 in the body, as shown. Figure 1 As shown. Figure 1 A schematic diagram is shown where the retaining part is a second hook 213. However, this is not the only possibility; the retaining part can also be any other structure with a diameter larger than that of the stent body 210. The renal pelvis end and bladder end of the stent body 210 are connected by a connecting part 214, such as... Figure 1 As shown. For example, the connecting part 214 is typically a straight structure.

[0048] In some embodiments, the self-discharge assembly includes a self-discharge line 110, such as Figure 8 As shown. The self-unloading cable 110 has a first fixed end 111 and a second fixed end 112, as follows. Figure 8 As shown. The first fixing end 111 is used for fixed connection with the ureteral stent 200. By applying force to the second fixing end 112, the ureteral stent 200 can be expelled from the body, as shown. Figure 2 As shown. Exemplarily, when the self-draining cable 110 is inside the body, force can be applied to the second fixed end 112 via the self-draining body 130; when the self-draining cable 110 is outside the body, force can be applied to the second fixed end 112 by an operator. Preferably, the self-draining assembly further includes a self-draining body 130, which is connected to the second fixed end 112 of the self-draining cable 110, as shown. Figure 2 As shown. Thus, the ureteral stent 200 can be expelled from the body by applying force to the self-expulsion line 110 through the self-expulsion body 130.

[0049] For example, the first fixed end 111 and the second fixed end 112 refer to a section of the self-unloading cable 110 near both ends of the self-unloading cable 110. For instance, the first fixed end 111 and the second fixed end 112 refer to the self-unloading cable 110 located less than 5 cm from the end of the self-unloading cable 110, and are not limited to both ends of the self-unloading cable 110.

[0050] In some embodiments, the self-discharging assembly further includes a biodegradable fixing portion 120, such as... Figure 5 As shown. The biodegradable fixing part 120 is used to fix the self-unloading cable 110. Exemplarily, the biodegradable fixing part 120 is made of a material that loses mass or mechanical properties over time in water. For example, the biodegradable fixing part 120 is made of biodegradable materials such as PLA, PGA, and PLGA; or the biodegradable fixing part 120 is made of water-soluble materials such as gelatin, polyvinyl alcohol, and sodium alginate. The biodegradable fixing part 120 can be prepared in the form of a coating, film, or heat shrink tubing. It is not limited to this; the biodegradable fixing part 120 can also be in the form of fibers.

[0051] In some embodiments, the self-draining wire 110 between the first fixing end 111 and the second fixing end 112 is at least partially coiled around the ureteral stent 200, and the self-draining wire 110 coiled around the ureteral stent 200 is detachably fixed to the ureteral stent 200 by a biodegradable fixing part 120, such as... Figures 2-5 As shown ( Figures 2-4 (The biodegradable fixing part 120 is not shown in the diagram). The biodegradable fixing part 120 is provided so that the self-draining wire 110 can be released from the ureteral stent 200 when it is necessary to remove the ureteral stent 200. For example, the biodegradable fixing part 120 can be formed by connecting the self-draining wire 110 and the ureteral stent 200 together through coating, film application, heat shrinking, fiber winding, etc., to form a detachable fixing point.

[0052] In this embodiment, the self-draining assembly has a self-draining wire 110 that is at least partially coiled around the ureteral stent 200. The self-draining wire 110 is detachably fixed to the ureteral stent 200 by the biodegradable fixing part 120. This allows the self-draining wire 110 and the self-draining body 130 of the self-draining assembly to be confined within the body, thus avoiding technical problems such as the high risk of infection caused by the self-draining wire 110 remaining outside the body, the risk of accidental traction of the self-draining wire 110 causing displacement of the ureteral stent 200, and the potential for complications.

[0053] On the other hand, to ensure that the self-extruding thread 110 can be expelled and that it is expelled to a certain length to pull the ureteral stent 200, the length of the self-extruding thread 110 is usually greater than 20cm, generally around 35cm. Such a long self-extruding thread 110 is usually bent and fixed with the biodegradable fixing part 120. Typically, the bending angle of the self-extruding thread 110 is close to 180°, and the number of bends is 3 to 6. Such a large bending angle causes the self-extruding thread 110 to bend at the inflection point, making it difficult to straighten when subjected to the action of the self-extruding body 130, affecting the reliability of the expulsion of the ureteral stent 200. In addition, the self-extruding thread 110 is relatively thin (usually with a diameter of 0.3 to 0.5 mm) and has weak torsional resistance. Even a small external force (while the self-extruding thread 110 is in the body, it will be affected by fluid impact, bladder contraction force, or relaxation force, etc.) can cause the self-extruding thread 110 to spiral twist and knot, which also affects the reliability of the expulsion of the ureteral stent 200.

[0054] In this embodiment, the self-draining assembly has the self-draining cable 110 at least partially coiled around the ureteral stent 200, resulting in a shorter length of the movable portion of the self-draining cable 110 within the bladder (e.g., Figure 5 As shown in the diagram, this reduces the risk of the self-draining suture 110 becoming entangled or knotted with the ureteral stent 200. Specifically, the shorter length of the movable portion of the self-draining suture 110 reduces the probability of it becoming entangled or knotted with the ureteral stent 200. Furthermore, the shorter length of the movable portion of the self-draining suture 110 also means a shorter portion of it being twisted by external forces within the bladder cavity, further reducing the risk of it becoming entangled or knotted with the ureteral stent 200 within the bladder.

[0055] In this embodiment, the self-draining assembly has the self-draining cable 110 at least partially coiled around the ureteral stent 200. This design, because the connecting portion 214 of the ureteral stent 200 is relatively long, reduces the number of times the self-draining cable 110 is folded, thereby reducing the risk of bending. Figure 2 As shown; or when the self-draining cable 110 is coiled around the ureteral stent 200, the bending angle at the inflection point can be less than 180°, thereby further reducing the risk of bending at the inflection point of the self-draining cable 110, such as Figure 3 or Figure 4 As shown. Therefore, in this embodiment, the self-draining line 110 is at least partially coiled around the ureteral stent 200, so that the self-draining line 110 can be easily straightened when subjected to the self-draining body 130, thereby further improving the reliability of the ureteral stent 200 discharge.

[0056] In some embodiments, for a double-J ureteral stent, the highest point of the self-draining line 110 is located above the highest point of the second hook 213 of the ureteral stent 200, such as... Figures 2-5As shown. Exemplarily, the ureteral stent 200 has a bladder marker band that is tangential to the upper part of the second hook 213. When the ureteral stent 200 is indwelling, the bladder marker band is located at the junction of the ureter and the renal pelvis. In this embodiment, the highest point of the self-draining line 110 is located above the highest point of the second hook 213 of the ureteral stent 200, ensuring that the self-draining line 110 located above the second hook 213 remains in the ureter. This is not a limitation; this application can also be applied to other types of ureteral stents, as long as the self-draining line 110 is at least partially coiled around the ureteral stent 200 and partially remains in the ureter.

[0057] In this embodiment, the self-draining suture 110 is at least partially coiled around the ureteral stent 200, allowing it to remain partially within the ureter. The suture 110 can only be expelled after the edema at the bladder-ureter junction has completely subsided. Specifically, the placement of the ureteral stent 200 is mostly used after ureteral obstruction or urinary calculi surgery. These two procedures generally cause edema at the ureter-bladder junction during the operation. With related techniques that place the self-draining suture 110 in the bladder, it is possible that the suture 110 will be expelled before the edema subsides. To prevent retrograde bacterial growth or accidental traction, the ureteral stent 200 must be removed while the edema is present. When the self-draining suture 110 is in the ureter, edema will to some extent hinder its descent, slowing its discharge. Once the edema at the junction of the bladder and ureter has completely subsided, the suture 110 can be discharged. At this point, removing the ureteral stent 200 can improve the patient's experience and the safety of its discharge. On the other hand, leaving at least part of the suture 110 in the ureter can reduce irritation to the bladder, thus alleviating symptoms such as urinary frequency.

[0058] In some embodiments, the length of the self-exiting wire 110 wound around the ureteral stent 200 satisfies the following condition: for a double-J ureteral stent, the center of the self-exiting body 130 is lower than the lowest point of the bladder end hook of the ureteral stent 200, such as... Figures 2-5 As shown. The bladder end hook of the ureteral stent 200 is also the second hook 213. This avoids the risk of the self-extrusion body 130 repeatedly entering and exiting the second hook 213 during the process of being shaken by force in the body, which could lead to the self-extrusion wire 110 not coiled on the ureteral stent 200 getting tangled with the ureteral stent 200, or the self-extrusion wire 110 not coiled on the ureteral stent 200 getting tangled with the self-extrusion wire 110 coiled on the ureteral stent 200. This can further improve the reliability of the ureteral stent 200 being expelled.

[0059] In some embodiments, the distance between the self-extruding body 130 and the lowest point of the bladder end hook of the ureteral stent 200 is 10-60 mm. Preferably, the distance between the self-extruding body 130 and the lowest point of the bladder end hook of the ureteral stent 200 is 10-23 mm. For example, the distance between the self-extruding body 130 and the lowest point of the bladder end hook of the ureteral stent 200 is 10 mm; or the distance between the self-extruding body 130 and the lowest point of the bladder end hook of the ureteral stent 200 is 16 mm; or the distance between the self-extruding body 130 and the lowest point of the bladder end hook of the ureteral stent 200 is less than 23 mm.

[0060] In this embodiment, the position of the self-exhausting body 130 is such that its center is lower than the lowest point of the second hook 213, and the distance between the self-exhausting body 130 and the lowest point of the second hook 213 is 10-60 mm. This position also allows the self-exhausting body 130 to be located between the bladder trigone and the bladder neck, thus reducing the stimulation of the bladder by the self-exhausting body 130 and further alleviating symptoms such as urinary frequency. In addition, when the guidewire is inserted, the position of the self-exhausting body 130 ensures that the guidewire passes through the self-exhausting body 130 first and then through the second hook 213; when the guidewire is withdrawn, the second hook 213 returns to its original shape first, ensuring that the self-exhausting body 130 will not become entangled in the circle formed by the second hook 213.

[0061] In some embodiments, the length of the self-draining cord 110 is greater than 35 cm. Preferably, the length of the self-draining cord 110 is 20-35 cm. At least 50% of the length of the self-draining cord 110 is located above the highest point of the second hook 213 of the ureteral stent 200. That is, at least 50% of the length of the self-draining cord 110 is located inside the ureter, which further reduces the risk of the self-draining cord 110 becoming entangled in the ureteral stent 200 or itself.

[0062] In some embodiments, the portion of the self-draining cable 110 wound around the ureteral stent 200 is U-shaped, Z-shaped, or X-shaped. Figure 2 A schematic diagram shows the portion of the self-draining line 110 coiled around the ureteral stent 200 in a U-shape. This structure allows the self-draining line 110 to be bent only once, and the self-draining line 110 can be easily straightened when subjected to the action of the self-draining body 130. Figure 3 and Figure 4 The diagram shows a Z-shaped or X-shaped portion of the self-draining cord 110 coiled around the ureteral stent 200. This structure, with a bending angle of less than 180°, also allows the self-draining cord 110 to easily straighten under the action of the self-draining body 130. The self-draining cord 110 is not limited to the three coiling methods described above and can also have other structures.

[0063] In some embodiments, when the self-draining cable 110 is coiled around the ureteral stent 200, the self-draining cable 110 at the inflection point forms a first arc-shaped structure 113, such as... Figures 2-4As shown. The self-aligning wire 110 has a first arc structure 113 at the inflection point, which makes it difficult for the self-aligning wire 110 to form a 180° bend at the inflection point (especially for self-aligning wire 110 made of monofilament, it is very easy to form a 180° bend at the inflection point), thus making it easy for the self-aligning wire 110 to straighten when subjected to the action of the self-aligning body 130.

[0064] In some embodiments, the self-draining line 110 located at the curved section of the ureteral stent 200 has a second arcuate structure 114 along the shape of the ureteral stent 200. For example... Figures 2-5 As shown, the self-draining line 110 located at the second hook 213 is distributed along the shape of the second hook 213. This allows the self-draining line 110 to easily straighten when subjected to the action of the self-draining body 130. In some embodiments, the self-draining line 110 is coiled around the outer or inner wall of the ureteral stent 200. Coiling the self-draining line 110 around the outer wall of the ureteral stent 200 is simple to operate. Not limited to this, an inner cavity can also be formed on the ureteral stent 200, and the self-draining line 110 can be coiled around the inner wall of the ureteral stent 200.

[0065] In some embodiments, the self-contained cable 110 is a monofilament. Exemplarily, the monofilament material is nylon, PTFE, or TPU. However, it is not limited to these materials and the monofilament may also be made of other materials.

[0066] In some embodiments, the self-draining line 110 is multifilament. Exemplarily, the multifilament material is PE, PET, or aramid. It is not limited to these, and the multifilament can also be other materials. In this embodiment, the self-draining line 110 is preferably multifilament, which is less prone to bending after prolonged winding, has stronger ability to float with water, and is more flexible, ensuring the reliability of the self-draining line 110's discharge.

[0067] Preferably, the fineness of the multifilament is not less than 10D. More preferably, the fineness of the multifilament is 30D~50D, which can ensure the strength of the self-draining line 110, and at the same time avoid the hidden danger that the self-draining line 110 is too fluid with water and therefore difficult to drain.

[0068] Preferably, the surface of the self-exhaust line 110 is provided with an antibacterial coating, which can reduce the risk of infection.

[0069] Preferably, the surface of the self-exhaust line 110 is provided with an anti-caking coating, which can reduce the risk of crusting on the surface of the self-exhaust line 110. The antibacterial coating and the anti-caking coating can be made of known materials in the prior art.

[0070] Preferably, the self-unwinding cable 110 is also provided with multiple anti-tangle points 140 at intervals, such as... Figure 8As shown. Preferably, the spacing between two adjacent anti-tangle points 140 is 1cm to 10cm. More preferably, the spacing between two adjacent anti-tangle points 140 is 4cm to 6cm. Preferably, the anti-tangle points 140 can be formed by dispensing adhesive. More preferably, the dispensing length can be controlled within 10mm, that is, the length of the anti-tangle point 140 is within 10mm, to avoid the risk of excessive dispensing length, which would result in greater stiffness of the self-releasing cable 110 and make it difficult to float with water. Preferably, the anti-tangle points 140 can be formed by knotting. When the self-releasing cable 110 is made of non-braided multifilament, because multifilament has a strong ability to float with water, two strands of multifilament are prone to knotting after repeated crossing and overlapping. By providing multiple anti-tangle points 140 at intervals on the self-releasing cable 110, the risk of tangling of the self-releasing cable 110 can be reduced.

[0071] Preferably, the self-layout cable 110 can also be made of braided multifilament. Braided multifilament has the advantage of being less prone to knotting, and with braided multifilament, the anti-tangle point 140 does not need to be added. For example, the outer diameter of the self-layout cable 110 formed by braided multifilament is greater than 0.05 mm.

[0072] In some embodiments, there are multiple biodegradable fixing parts 120, and the biodegradable fixing parts 120 are spaced apart on the self-draining line 110, such as... Figure 5 As shown. Preferably, the biodegradable fixing part 120 is one or more of a sleeve, heat shrink tubing, coating, and knot. For example, when the biodegradable fixing part 120 is in the form of a sleeve, heat shrink tubing, etc., the length of the biodegradable fixing part 120 is 1-4 mm; when the biodegradable fixing part 120 is in the form of a coating, the thickness of the biodegradable fixing part 120 is 20-50 μm; when the biodegradable fixing part 120 is in the form of a knot, the outer diameter of the biodegradable fixing part 120 is 0.05-0.25 mm. Through multiple biodegradable fixing parts 120, the self-draining cord 110 can be securely coiled around the ureteral stent 200. Preferably, the biodegradable fixing part 120 is located at the inflection point of the self-draining cord 110. This not only serves to fix the self-draining cord 110, but also helps maintain the first arc-shaped structure 113 at the inflection point of the self-draining cord 110. However, it is not limited to this; the biodegradable fixing part 120 can also be provided at other parts of the self-draining cord 110.

[0073] In some embodiments, the fixed connection point 150 is where the first fixed end 111 is fixedly connected to the ureteral stent 200, such as... Figure 6 and Figure 7 As shown. The fixed connection point 150 is located at the end of the ureteral stent 200, as... Figure 6 and Figure 7 As shown. Preferably, the self-draining line 110 near the first fixed end 111 faces the end of the ureteral stent 200, as shown. Figure 6 or Figure 7As shown. The first fixed end 111 is fixedly connected to the ureteral stent 200 near its end. During the pulling process, the second hook 213 of the ureteral stent 200 can be straightened. Furthermore, the self-draining line 110 near the first fixed end 111 faces the end of the ureteral stent 200. When force is applied to the self-draining line 110, the tension of the self-draining line 110 is directed towards the end of the ureteral stent 200, making it easier to straighten the second hook 213 of the ureteral stent 200.

[0074] In some embodiments, the fixed connection point 150 can be formed by adhesive bonding, hot pressing, or wrapping and knotting. Preferably, the ureteral stent 200 has a first through hole 211, and the first fixed end 111 passes through the first through hole 211, forming the fixed connection point 150 at the connection between the first fixed end 111 and the first through hole 211. For example, the first fixed end 111 is inserted into the first through hole 211 and then directly knotted, such as... Figure 6 As shown. Preferably, the first fixing end 111 is wound around the end of the ureteral stent 200, and a fixing connection point 150 is formed at the starting point of the winding of the first fixing end 111, as shown. Figure 7 As shown. For example, the first fixing end 111 is tightly wrapped around the end of the ureteral stent 200 multiple times and then knotted, as shown. Figure 7 As shown. The length of the wrapped portion is 1~3mm.

[0075] In this embodiment, the self-draining component preferably forms the fixed connection point 150 by wrapping and knotting. Forming the fixed connection point 150 by wrapping and knotting not only facilitates processing, but also makes it less likely to damage the coating during processing or pulling when the ureteral stent 200 has a coating.

[0076] On the other hand, the length of the self-draining cord 110 winding portion is 1~3mm, which can increase the reliability of the connection between the self-draining cord 110 and the ureteral stent 200, and avoid the risk of the self-draining cord 110 falling off when the pulling force is large (a large force is usually required to be applied to the self-draining cord 110 in a narrow position), thereby further improving the reliability of the ureteral stent 200 being discharged.

[0077] In some embodiments, the self-excreting body 130 is made of a material with a density greater than water, or it is made of a highly absorbent material. By utilizing its own weight or by absorbing water to increase its weight, the self-excreting body 130 can point towards the internal urethral orifice within the bladder, facilitating expulsion. Exemplarily, the self-excreting body 130 can be made of metallic materials, such as stainless steel, titanium, or other metallic materials; it can also be made of polymeric materials, such as polytetrafluoroethylene, nylon, POM, or other polymeric materials; or it can be made of inorganic non-metallic materials, such as zirconium oxide, silicon nitride, or other inorganic non-metallic materials.

[0078] In some embodiments, the number of self-exit bodies 130 is at least one. Preferably, the number of self-exit bodies 130 is 1 to 10. More preferably, the number of self-exit bodies 130 is 2 to 4. For example, when there is only one self-exit body 130, it can be fixed 0 to 5 mm from the end of the self-exit cable 110. For example, when there are two or more self-exit bodies 130, they are spaced apart, such as... Figure 9 As shown. The distance between two adjacent self-extrusion bodies 130 is 0~5cm, preferably 1~2cm, and the last self-extrusion body 130 is fixed at 0~5mm from the end of the self-extrusion line 110. By setting multiple self-extrusion bodies 130, the flexible self-extrusion line 110 can be easily straightened, thereby reducing the difficulty of expelling the ureteral stent 200.

[0079] In some embodiments, the self-draining body 130 has a structure with rounded edges. For example, the self-draining body 130 is spherical. Preferably, the self-draining body 130 should be larger than the outer diameter of the self-draining line 110 (when the self-draining body 130 is made of a highly absorbent material, its size after absorbing water should be larger than the outer diameter of the self-draining line 110), thus the larger cross-sectional area allows for greater drainage / attraction of water to the self-draining body 130. For example, the maximum size of the self-draining body 130 is 0.5~5mm. More preferably, the maximum size of the self-draining body 130 is 1~2mm. Based on the ease of processing the material of the self-draining body 130, the self-draining body 130 is formed into a spherical shape or other irregular structure with rounded edges, thus making the self-draining body 130 not only easy to discharge during the discharge process but also reducing damage to human body cavities.

[0080] In some embodiments, the self-draining body 130 may also be made of a highly absorbent material, such as a functional substance capable of absorbing tens to hundreds of times its own weight in water, like modified fibers or absorbent resins. This type of self-draining body 130 can be connected to the self-draining line 110 through physical weaving, knotting, or adhesive bonding.

[0081] The self-extruding body 130, made of highly absorbent material, is easy to retain in the body. When the self-extruding body 130 is a spherical object with a density greater than water, its movement within the body due to its own weight can cause some irritation to the bladder. The highly absorbent material increases its weight and volume by absorbing water, thus it can be a very small component before entering the body. During retention, it has less contact with the body's natural cavities, resulting in less irritation to the bladder. Furthermore, the irritation caused by the movement of the self-extruding body 130 within the bladder during the period from initial water absorption to complete water absorption is even less. The highly absorbent material is preferably made of cellulose, resin, or similar materials, which, after absorbing water, are more fluffy than materials with a density greater than water, resulting in less impact force against the bladder wall.

[0082] In some embodiments, when the self-draining body 130 is made of a highly absorbent material, its length is less than 10 mm, preferably 3 mm to 5 mm. Preferably, the very end of the self-draining body 130 is braided into strands or knots; after absorbing water, the increased gravity is concentrated, making it easier to move downwards with urine within the urethra. The self-draining body 130 can be multiple segments, preferably 1 to 3 segments. When the self-draining body 130 is only one segment, it can be located at the very end of the self-draining line 110. When there are two or more self-draining bodies 130, the distance between two adjacent self-draining bodies 130 can be 0 cm to 5 cm, preferably 1 cm to 2 cm.

[0083] In some embodiments, the self-discharging body 130 may be made of both a material with a density greater than water and a highly absorbent material, which can work together to exert force on the self-discharging line 110. Not limited to this, the self-discharging body 130 may be made of a material with a density less than water, in which case a highly absorbent material is added to the tail end of the self-discharging line 110, which can help increase the total weight of the self-discharging body 130.

[0084] In some embodiments, the self-exit body 130 and the self-exit cable 110 can be fixedly connected by physical interception or chemical bonding. For example, the self-exit body 130 has a second through hole 131, the second fixing end 112 passes through the second through hole 131, and then the self-exit cable 110 is knotted and fixed, such as... Figure 10 and Figure 11 As shown. Furthermore, to ensure the fixation effect of the self-draining body 130, the second fixing end 112 can be inserted and exited through the second through hole 131 multiple times. By fixing the self-draining body 130 with the second through hole 131, the second through hole 131 can also allow the guide wire to pass through, avoiding the potential problem of the large-sized ureteral stent 200 being difficult to pass through when running parallel to the self-draining body 130.

[0085] For example, the self-discharging body 130 and the second fixed end 112 can also be fixedly connected by adhesive, such as... Figure 12 As shown. For example, the second fixed end 112 can be wound around the self-draining body 130 to achieve a fixed connection.

[0086] The ureteral stent of this embodiment includes a stent body 210. The structure of the stent body 210 has been described in the preceding embodiments and will not be detailed here. The ureteral stent 200 of this embodiment also includes a self-draining component, which is the self-draining component of any of the technical solutions in the preceding embodiments, and the self-draining component is disposed on the stent body 210, such as... Figures 2-5 As shown. The ureteral stent 200 of this embodiment can also be called an implantable self-draining ureteral stent.

[0087] The ureteral stent 200 of this embodiment, through the improved self-extraction component, can confine the self-extraction line 110 and the self-extraction body 130 within the body, avoiding the technical problems of the self-extraction line 110 being left outside the body, which leads to a high risk of infection, accidental traction of the self-extraction line 110 causing displacement of the ureteral stent 200, and easy occurrence of complications; in addition, the ureteral stent 200 of this embodiment can also improve the reliability of the self-extraction of the ureteral stent 200.

[0088] The above description is merely a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any changes or substitutions that can be easily conceived by those skilled in the art within the scope of the technology disclosed in the present invention should be included within the scope of protection of the present invention.

Claims

1. A self-arranging assembly for use in a ureteral stent (200), characterized in that, The self-discharge assembly comprises a self-discharge wire (110), a degradable fixing part (120) and a self-discharge body (130), wherein, The self-discharge wire (110) has a first fixed end (111) and a second fixed end (112), the first fixed end (111) is used for fixed connection with the ureteral stent (200), and the second fixed end (112) is used for fixed connection with the self-discharge body (130); The self-discharge wire (110) between the first fixed end (111) and the second fixed end (112) is at least partially coiled on the ureteral stent (200), and the self-discharge wire (110) is detachably fixed with the ureteral stent (200) through the degradable fixing part (120).

2. The self-draining assembly of claim 1, wherein, For a double J type ureteral stent, the highest point of the self-discharge wire (110) is located above the highest point of the second hook (213) of the ureteral stent (200), and the self-discharge wire (110) is at least partially located in the ureter; And / or, the length of the self-discharge wire (110) coiled on the ureteral stent (200) satisfies: for a double J type ureteral stent, the center of the self-discharge body (130) is lower than the lowest point of the bladder end hook of the ureteral stent (200).

3. The self-draining assembly of claim 2, wherein, The distance between the self-discharge body (130) and the lowest point of the bladder end hook of the ureteral stent (200) is 10-60mm; And / or, the length of the self-discharge wire (110) is greater than 35cm, and at least 50% of the length of the self-discharge wire (110) is located above the highest point of the second hook (213) of the ureteral stent (200).

4. The self-draining assembly of any of claims 1-3, wherein, The self-discharge wire (110) is coiled on the outer wall or the inner wall of the ureteral stent (200); And / or, when the self-discharge wire (110) is coiled on the ureteral stent (200), the self-discharge wire (110) located at the inflection point is in a first arc structure (113); And / or, the self-discharge wire (110) located at the curved segment of the ureteral stent (200) is in a second arc structure (114) along the shape of the ureteral stent (200); And / or, the part of the self-discharge wire (110) coiled on the ureteral stent (200) is in a U shape, a Z shape or an X shape.

5. The self-draining assembly of any one of claims 1-3, wherein, The self-discharge wire (110) is a monofilament; Or, the self-discharge wire (110) is a multifilament, the fineness of the multifilament is not less than 10D, and / or a plurality of anti-winding points (140) are further arranged on the self-discharge wire (110), and / or an antibacterial coating is arranged on the surface of the self-discharge wire (110); and / or an anti-crusting coating is arranged on the surface of the self-discharge wire (110).

6. The self-draining assembly of claim 5, wherein, The degradable fixing parts (120) are a plurality of and are arranged on the self-discharge wire (110) at intervals; And / or, the degradable fixing parts (120) are arranged at the inflection points of the self-discharge wire (110); And / or, the degradable fixing parts (120) are one or more of a sleeve, a heat shrink tube, a coating and a knot.

7. The self-draining assembly of any of claims 1-3, wherein, The ureteral stent (200) is provided with a first through hole (211), the first fixed end (111) is arranged in the first through hole (211), and the first fixed end (111) and the first through hole (211) are connected to form a fixed connection point (150), and the self-dispersion wire (110) close to the first fixed end (111) is directed to the end of the ureteral stent (200); Or, the first fixed end (111) is wound on the end of the ureteral stent (200), the winding starting point of the first fixed end (111) forms a fixed connection point (150), the fixed connection point (150) is 1-3mm away from the end of the ureteral stent (200), and the self-dispersion wire (110) close to the first fixed end (111) is directed to the end of the ureteral stent (200).

8. The self-draining assembly of any of claims 1-3, wherein, The number of the self-dispersion body (130) is at least one; when the number of the self-dispersion body (130) is two or more, the self-dispersion bodies (130) are arranged at intervals; And / or, the self-dispersion body (130) is a structure with a smooth edge; And / or, the maximum size of the self-dispersion body (130) is 1-2mm; And / or, the self-dispersion body (130) is made of a material with a density greater than water, or the self-dispersion body (130) is made of a superabsorbent material.

9. The self-draining assembly of claim 8, wherein, The self-dispersion body (130) is provided with a second through hole (131), and the second fixed end (112) is arranged in the second through hole (131); Or, the self-dispersion body (130) and the second fixed end (112) are fixedly connected by adhesion; Or, the second fixed end (112) is wound on the self-dispersion body (130) to realize fixed connection.

10. A ureteral stent, characterized in that, The ureteral stent comprises a stent body (210) and a self-dispersion assembly, the self-dispersion assembly is the self-dispersion assembly according to any one of claims 1 to 9, and the self-dispersion assembly is arranged on the stent body (210).

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