Multi-station full-automatic drop dyeing HE dyeing machine

By designing a multi-station fully automatic HE staining machine, and utilizing the coordinated operation of the feeding and heating mechanism, the material hopper channel, and the discharging mechanism, a fully automated production line operation for tissue sections is achieved, solving the problem of low automation in existing HE staining equipment and improving staining efficiency.

CN121026726BActive Publication Date: 2026-02-17GUANGDONG JINQUAN MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202511544167.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-10-28
Publication Date
2026-02-17
Estimated Expiration
2045-10-28

AI Technical Summary

Technical Problem

Existing HE staining equipment has a low degree of automation and low efficiency, and most of them can only perform single-station operations, which makes it difficult to meet the needs of large-scale sample processing.

Method used

Design a multi-station fully automatic HE staining machine, including a feeding and heating mechanism, a material hopper channel, multiple processing stations and a discharging mechanism, to realize fully automatic production line operation of tissue sections, and achieve multi-station staining through collaborative cooperation.

Benefits of technology

It significantly improves the equipment's throughput and staining efficiency, making it suitable for processing large batches of samples and enabling efficient multi-station staining of tissue sections.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application discloses a kind of multi-station full-automatic drop dyeing HE dyeing machine, including machine table, be equipped with feeding warming mechanism, material bin flow channel and discharging mechanism on machine table;Feeding warming mechanism is used to be transported to material bin in material bin flow channel;Multiple second processing positions are equipped on machine table, multiple material bin pushing mechanisms are equipped on material bin flow channel, and material bin pushing mechanism is used to push material bin to slide on material bin flow channel;Discharging mechanism includes discharging pushing mechanism and discharging flow channel, and the middle part of discharging flow channel is equipped with first processing position;Discharging pushing mechanism can push material bin to first processing position, also can push material bin on first processing position to discharge end;Liquid injection mechanism and waste liquid recovery mechanism are equipped on machine table, liquid injection mechanism is used to inject liquid medicine into material bin, and waste liquid recovery mechanism is used to draw away waste liquid in material bin.The application can realize tissue section from warming, multi-station dyeing to the full-automatic assembly line operation of discharging, significantly improve equipment processing flux and dyeing efficiency.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical auxiliary apparatus, in particular to a multi-station full-automatic drop dyeing HE dyeing machine. BACKGROUND

[0002] Dyeing has great significance in the diagnosis of pathological histology, scientific experimental research and teaching work. If the tissue section is not dyed, the internal structure of the tissue cannot be seen, and the cell nucleus cannot be distinguished, so that the researchers cannot provide a basis for judgment to judge whether the tissue is abnormal.

[0003] HE dyeing is to dye the nucleus and cytoplasm with hematoxylin and eosin respectively, which can distinguish the morphology of general cells. In practical application, it can identify abnormal pathological changes such as tissue cell necrosis, edema, degeneration and inflammatory cell infiltration.

[0004] When dyeing the tissue section, the common way is still manual operation, which has very low processing efficiency. Even if there are some HE dyeing equipment, the automation degree is still very low, and only one station is used for dyeing, which has very low efficiency. Therefore, it is necessary to design an HE dyeing equipment capable of realizing multi-functional automatic operation. SUMMARY

[0005] In order to solve the problems in the prior art, the present application provides a multi-station full-automatic drop dyeing HE dyeing machine, which comprises a machine table, an upper feeding and heating mechanism, a material bin flow channel and a discharging mechanism are arranged on the machine table, one end of the material bin flow channel is connected with the upper feeding and heating mechanism, and the other end is connected with the discharging mechanism; the upper feeding and heating mechanism is used for heating the tissue section in the material bin, and conveying the heated material bin into the material bin flow channel; a plurality of second processing stations are arranged on the machine table corresponding to the material bin flow channel, a plurality of material bin pushing mechanisms are arranged on the material bin flow channel, the material bin pushing mechanisms are used for pushing the material bin to slide on the material bin flow channel, so that the material bin is respectively moved to each second processing station; the discharging mechanism comprises a discharging pushing mechanism arranged on the machine table and a discharging flow channel, one end of the discharging flow channel is a discharging end, the other end is connected with the material bin flow channel, and a first processing station is arranged in the middle of the discharging flow channel; the discharging pushing mechanism is connected with the material bin flow channel and the discharging flow channel respectively, and the discharging pushing mechanism can push the material bin in the material bin flow channel to the first processing station, and also can push the material bin on the first processing station to the discharging end; a liquid injection mechanism and a waste liquid recovery mechanism are arranged on the machine table corresponding to the first processing station and each second processing station respectively, the liquid injection mechanism is used for injecting liquid medicine into the material bin, and the waste liquid recovery mechanism is used for pumping away the waste liquid in the material bin.

[0006] As a further improvement of the present application, the feeding and warming mechanism comprises a feeding mechanism, a baking oven and a feeding pushing mechanism arranged on the machine table respectively; the feeding mechanism comprises a feeding lifting module, the feeding lifting module is connected with the machine table, a feeding tray is arranged on the output end of the feeding lifting module, the feeding tray is used for placing a material bin containing tissue slices, the feeding lifting module can drive the feeding tray to move up and down, thereby driving the material bin to extend into or out of the baking oven, the baking oven is used for warming the tissue slices in the material bin, and the feeding pushing mechanism is connected with the feeding mechanism and the material bin flow channel respectively, and is used for pushing the material bin on the feeding tray into the material bin flow channel.

[0007] As a further improvement of the present application, the material bin flow channel is provided with a blocking mechanism and a positioning mechanism at positions corresponding to each second processing position respectively, the blocking mechanism is used for blocking the sliding of the material bin in the material bin flow channel, and the positioning mechanism is used for limiting the position of the material bin in the material bin flow channel corresponding to the second processing position.

[0008] As a further improvement of the present application, the material bin pushing mechanism comprises a pushing fixed frame, the pushing fixed frame is connected with the machine table, a material bin pushing motor and a material bin pushing driven wheel are arranged on the pushing fixed frame, a material bin pushing driving wheel is arranged on the output end of the material bin pushing motor, a material bin pushing transmission belt is sleeved on the material bin pushing driving wheel and the material bin pushing driven wheel, a material bin pushing sliding block is arranged on the material bin pushing transmission belt, and a material bin pushing block is arranged on the material bin pushing sliding block, the material bin pushing block can abut against the material bin in the material bin flow channel.

[0009] As a further improvement of the present application, the machine table is provided with a dyeing mounting frame, the liquid injection mechanism comprises a liquid injection horizontal movement module, the liquid injection horizontal movement module is connected with the dyeing mounting frame, a liquid injection lifting mounting plate is arranged on the output end of the liquid injection horizontal movement module, a liquid injection lifting module and a needle tube cleaning assembly are arranged on the liquid injection lifting mounting plate, a liquid injection needle is arranged on the output end of the liquid injection lifting module, a liquid injection pump is connected with one end of the liquid injection needle, the liquid injection horizontal movement module and the liquid injection lifting module can drive the liquid injection needle to extend into each material groove of the material bin respectively, the liquid injection lifting module can also drive the liquid injection needle to be connected with the needle tube cleaning assembly, and the needle tube cleaning assembly is used for cleaning the liquid injection needle.

[0010] As a further improvement of the application, the lower end face of the liquid injection needle is a sealing structure, and the liquid outlet hole of the liquid injection needle is arranged on the side wall of the liquid injection needle; the needle tube cleaning assembly comprises a cleaning mounting frame, the cleaning mounting frame is connected with the liquid injection lifting mounting plate, a cleaning tank is arranged on the cleaning mounting frame, a needle passing hole penetrating through the upper and lower end faces of the cleaning tank is arranged in the cleaning tank, the liquid injection needle can pass through the needle passing hole and is in gap cooperation with the needle passing hole; a water inlet joint and a water outlet joint are arranged on the side wall of the cleaning tank, the water inlet joint and the water outlet joint are respectively connected with the needle passing hole, the water inlet joint is connected with a cleaning liquid, and the water outlet joint is connected with a negative pressure suction device.

[0011] As a further improvement of the application, the waste liquid recovery mechanism comprises a recovery horizontal movement module, the recovery horizontal movement module is connected with the dyeing mounting frame, a recovery lifting module is arranged on the output end of the recovery horizontal movement module, a liquid suction needle and a gas blowing assembly are arranged on the output end of the recovery lifting module, the liquid suction needle is connected with a negative pressure suction device, the gas blowing assembly is connected with a gas source, and the recovery horizontal movement module and the recovery lifting module can drive the liquid suction needle to extend into each tank of the material bin, and the gas blowing assembly is used for blowing gas into the tank.

[0012] As a further improvement of the application, a position-avoiding rotary motor is arranged on the output end of the recovery lifting module, a rotary mounting block is arranged on the output end of the position-avoiding rotary motor, the position-avoiding rotary motor can drive the rotary mounting block to rotate, and the liquid suction needle and the gas blowing assembly are connected with the rotary mounting block respectively.

[0013] As a further improvement of the application, the gas blowing assembly comprises a gas nozzle, the gas nozzle is connected with the output end of the recovery lifting module, one end of the gas nozzle is connected with a gas source, the other end of the gas nozzle is provided with a triangular-shaped gas blowing part, and a plurality of gas blowing holes are arranged on the end face of the gas blowing part; the number of the liquid suction needles is two, and the two liquid suction needles are symmetrically distributed on the two sides of the gas nozzle, and the distance between the two liquid suction needles is less than the length of the tank.

[0014] As a further improvement of the application, the discharge pushing mechanism comprises a discharge pushing frame, the discharge pushing frame is connected with the machine table, a discharge motor is arranged on the discharge pushing frame, a discharge driving wheel is arranged on the output end of the discharge motor, discharge driven wheels are arranged at the two ends of the discharge pushing frame respectively, a discharge transmission belt is sleeved on the discharge driving wheel and the discharge driven wheels, and a discharge pushing block is arranged on the discharge transmission belt; a pushing block is arranged on the discharge pushing block, the pushing block can pass through the material bin flow channel and the discharge flow channel respectively, the pushing block is hinged with the discharge pushing block, the pushing block can swing around the hinge point as the axis, a pushing limiting column is arranged on the discharge pushing block, and the pushing block can abut against the pushing limiting column.

[0015] Compared with the prior art, the present application has the beneficial effects that:

[0016] The present application realizes the full-automatic assembly line operation of tissue section from warming, multi-station dyeing to discharging through the cooperation of the feeding and warming mechanism, the stock bin flow channel, the multiple processing stations and the discharging mechanism. The multiple processing stations can simultaneously perform dyeing operation, which significantly improves the equipment processing flux and dyeing efficiency and is suitable for large-batch sample processing. BRIEF DESCRIPTION OF DRAWINGS

[0017] In order to more clearly illustrate the schemes in the present application or the prior art, the drawings needed to be used in the following embodiments or prior art description will be briefly introduced. Obviously, the drawings in the following description are some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative effort on the basis of these drawings.

[0018] Figure 1 is a structural schematic diagram of a stock bin in an embodiment of the present application;

[0019] Figure 2 is another perspective structural schematic diagram of the stock bin in the embodiment of the present application;

[0020] Figure 3 is a whole structural schematic diagram of the embodiment of the present application;

[0021] Figure 4 is another perspective structural schematic diagram of the embodiment of the present application;

[0022] Figure 5 is a structural schematic diagram of a feeding mechanism in the embodiment of the present application;

[0023] Figure 6 is a structural schematic diagram of a feeding pushing machine in the embodiment of the present application;

[0024] Figure 7 is a local structural schematic diagram of the embodiment of the present application;

[0025] Figure 8 is a structural schematic diagram of a stock bin pushing mechanism in the embodiment of the present application;

[0026] Figure 9 is another perspective structural schematic diagram of the stock bin pushing mechanism in the embodiment of the present application;

[0027] Figure 10 is a local structural schematic diagram of the embodiment of the present application;

[0028] Figure 11 is a structural schematic diagram of a liquid injection transverse movement module in the embodiment of the present application;

[0029] Figure 12is a structural schematic view of the liquid injection lifting module in the embodiment of the present application;

[0030] Figure 13 is another perspective structural schematic view of the liquid injection lifting module in the embodiment of the present application;

[0031] Figure 14 is a structural schematic view of the needle tube cleaning assembly in the embodiment of the present application;

[0032] Figure 15 is a structural schematic view of the recovery lifting module in the embodiment of the present application;

[0033] Figure 16 is another perspective structural schematic view of the recovery lifting module in the embodiment of the present application;

[0034] Figure 17 is a structural schematic view of the blowing assembly in the embodiment of the present application;

[0035] Figure 18 is a structural schematic view of the discharge pushing mechanism in the embodiment of the present application;

[0036] Figure 19 is a structural schematic view of the discharge pushing mechanism in the embodiment of the present application; Figure 18 is an enlarged structural schematic view of part A in the embodiment of the present application;

[0037] Figure 20 is a structural schematic view of the processing blocking mechanism in the embodiment of the present application. DETAILED DESCRIPTION

[0038] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs; the terminology used in the specification is for describing particular embodiments only and is not intended to be limiting of the application; the present application is well suited to carry out the objects and advantages thereof with the use of the terms "comprise" and "have", and any variations thereof, are intended to cover a non-exclusive inclusion. The terminology used in the detailed description of the application and the claims, and the above abstract, is intended to be interpreted in accordance with the broadest interpretation allowed under the circumstances and the statement "comprising", "comprises" and "comprised of" used in the claims are not intended to exclude any features, additives, components or steps not specifically recited.

[0039] Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment of the application. The appearances of the phrase "in an embodiment" in various places in the specification are not necessarily all referring to the same embodiment, nor are they necessarily all directed to the same embodiments, alternative embodiments, or alternative implementations of the application. It is expressly understood that any of the embodiments of the application described herein are combinable with each other.

[0040] In order to enable the person skilled in the art to better understand the technical scheme of the present application, the technical scheme in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings.

[0041] As shown in Figures 1-20 A multi-station automatic drop dyeing HE dyeing machine, comprising a machine table 100, a feeding and warming mechanism 300, a hopper flow channel 200 and a discharging mechanism 400 are fixedly installed on the machine table 100, one end of the hopper flow channel 200 is connected with the feeding and warming mechanism 300, and the other end is connected with the discharging mechanism 400. The feeding and warming mechanism 300 is used for warming the tissue slices in the hopper, so that they are more easily dyed, and the feeding and warming mechanism 300 can also push the hoppers containing the warmed tissue slices into the hopper flow channel 200 in sequence.

[0042] Five second processing stations 500 are arranged along the line of the hopper flow channel 200 on the machine table 100, and in other embodiments, the number of second processing stations 500 can also be any other number, each second processing station 500 has the same function, which is to dye the tissue slices in the hopper 600. A plurality of hopper pushing mechanisms 210 are installed on the hopper flow channel 200, the hopper pushing mechanisms 210 are used to push the hoppers containing the tissue slices to slide in the hopper flow channel 200, thereby realizing the function of moving the hoppers to the second processing stations 500 for dyeing respectively.

[0043] The discharging mechanism 400 comprises a discharging pushing mechanism 410 and a discharging flow channel 420 arranged on the machine table 100, one end of the discharging flow channel 420 is a discharging end 421, the other end is connected with the hopper flow channel 200, and a first processing station 700 is arranged in the middle of the discharging flow channel 420. The first processing station 700 and the second processing station 500 have the same function, which is to dye the tissue slices in the hopper. The discharging pushing mechanism 410 is connected with the hopper flow channel 200 and the discharging flow channel 420 respectively, and the discharging pushing mechanism 410 can push the hoppers in the hopper flow channel 200 to the first processing station 700, and also can push the hoppers on the first processing station 700 to the discharging end 421. Through the discharging pushing mechanism 410, the hoppers after dyeing can be pushed out, and then the hoppers at the discharging end 421 can be taken away by manual or downstream equipment.

[0044] The machine table 100 is provided with a liquid injection mechanism 800 and a waste liquid recovery mechanism 900 at positions corresponding to the first processing position 700 and the second processing position 500 respectively, the liquid injection mechanism 800 is used to inject reagent into the hopper, and the waste liquid recovery mechanism 900 is used to pump away the waste liquid in the hopper. When the hopper pushing mechanism 210 or the discharge pushing mechanism 410 pushes the hopper to the processing position, the corresponding liquid injection mechanism 800 will start to work, and the reagent will be injected into the trough in the hopper to make the reagent contact with the tissue section, so as to realize the dyeing; after the dyeing is completed, the waste liquid remaining in the trough is pumped away by the waste liquid recovery mechanism 900; then the trough can be injected with new reagent by the liquid injection mechanism 800, and the waste liquid remaining in the trough is pumped away by the waste liquid recovery mechanism 900. Repeat the above action process, when the trough is completed, the next trough in the tissue section is dyed by the liquid injection mechanism 800 and the waste liquid recovery mechanism 900, until all the tissue sections in the trough are dyed.

[0045] As shown in Figure 1 It should be noted that the upper end of the hopper 600 is provided with a plurality of troughs 601 at equal intervals, and the trough 601 is used to place the slide 602 containing the tissue section.

[0046] In the actual processing process, the operator places the hopper carrying the tissue section on the feeding and warming mechanism 300, and completes the warming through the feeding and warming mechanism 300; then the feeding and warming mechanism 300 will transport the first hopper into the hopper flow channel 200. Then control each hopper pushing mechanism 210 to work in turn to push the hopper to the junction of the hopper flow channel 200 and the discharge flow channel 420. Then the first hopper is pushed to the first processing position 700 by the discharge pushing mechanism 410; then the corresponding liquid injection mechanism 800 and waste liquid recovery mechanism 900 of the first processing position 700 are controlled to work, and the tissue section in the hopper on the first processing position 700 is dyed; after the dyeing is completed, the hopper is pushed to the discharge end 421 by the discharge pushing mechanism 410, and the discharge is completed.

[0047] In the above processing process, when the first processing position 700 is pushed to the hopper, the feeding and warming mechanism 300 and the hopper pushing mechanism 210 continue to work to push the second hopper to the second processing position 500 closest to the discharge mechanism 400; then the corresponding liquid injection mechanism 800 and waste liquid recovery mechanism 900 of the second processing position 500 work to dye the tissue section in the hopper on the processing position; similarly, all the second processing positions 500 are dyed at the same time, so as to improve the processing efficiency.

[0048] In actual processing, because the first processing station 700 completes its feeding first, it will begin the dyeing process. Therefore, after dyeing is completed at the first processing station 700, the adjacent second processing station 500 will not have all its material troughs dyed. To avoid the first processing station 700 waiting, the material hopper on the first processing station 700 will be fed out, and the material hopper in the second processing station 500 that has not completed its dyeing process will be pushed to the first processing station 700 via the discharge pushing mechanism 410. The first processing station 700 will then take over the remaining dyeing work from the second processing station 500 until all material troughs in the hopper are dyed. Similarly, at each of the second processing stations 500, if the preceding second processing station 500 is short of material, the hopper pushing mechanism 210 will push the material hopper in the following second processing station 500 that has not completed its dyeing process to the preceding second processing station 500, whereby the preceding second processing station 500 will take over the remaining dyeing work.

[0049] In other embodiments, the first processing station 700 may be omitted, and the discharge mechanism 400 may simply send the dyed material from the second processing station 500 to the discharge end 421.

[0050] The feeding and heating mechanism 300 includes a feeding mechanism 310, a heating mechanism 320, and a feeding and pushing mechanism 330, all respectively mounted on the machine base 100. The feeding mechanism 310 is connected to both the heating mechanism 320 and the feeding and pushing mechanism 330. During processing, the manual operator first places the hopper containing tissue slices onto the feeding mechanism 310, then the feeding mechanism 310 lifts the hopper to the heating position of the heating mechanism 320. The heating mechanism 320 heats the tissue slices in the hopper. After heating, the feeding mechanism 310 lowers the hopper to a height that matches the hopper flow channel 200. Finally, the feeding and pushing mechanism 330 pushes the hopper into the hopper flow channel 200, thus completing the heating and feeding process.

[0051] like Figure 5 As shown, the feeding mechanism 310 includes a feeding fixed base 311 and a feeding tray 312. The feeding fixed base 311 is fixedly connected to the machine base 100, and a feeding lifting motor 313 is fixedly installed on the feeding fixed base 311. The output end of the feeding lifting motor 313 is connected to a feeding lifting screw 314. A feeding lifting slider 315 is sleeved on the feeding lifting screw 314. A lifting plate 316 is fixedly fixed to the bottom of the feeding tray 312, and the lifting plate 316 is fixedly connected to the feeding lifting slider 315. During processing, the operator first places the hopper containing tissue slices onto the feeding tray 312; then, by controlling the operation of the feeding lifting motor 313, the operator can drive the feeding lifting slider 315 to slide up and down on the feeding lifting screw 314. The feeding lifting slider 315 drives the lifting plate 316 and the feeding tray 312 to move together, so that the feeding tray 312 can drive the hopper to extend into or out of the heating mechanism 320.

[0052] To limit and guide the lifting movement of the feeding tray 312, lifting guide sleeves 317 are respectively provided at the four corner positions of the lifting plate 316. Lifting guide rods 318 are respectively provided on the feeding fixing seat 311 at corresponding positions of each lifting guide sleeve 317. The lifting guide rods 318 pass through the corresponding lifting guide sleeves 317, and the two are slidably engaged. When the feeding lifting motor 313 is working, the lifting plate 316 drives the lifting guide sleeves 317 to slide on the lifting guide rods 318, thereby guiding and limiting the lifting plate 316.

[0053] In other embodiments, the number of lifting guide rods 318 can also be any other number; it is only necessary to ensure that the lifting guide rods 318 and the lifting guide sleeves 317 are set in a one-to-one correspondence.

[0054] like Figure 3 As shown, the heating mechanism 320 includes a heating mounting frame 321, which is fixedly connected to the machine base 100. A baking oven 322 is fixedly mounted on the heating mounting frame 321 and positioned directly above the feeding tray 312. The lower end of the baking oven 322 has a hollow structure, allowing the feeding tray 312 to lift the material hopper and extend it into the baking oven 322. The baking oven 322 then heats the tissue sections within the hopper, ensuring uniform heating. The baking oven 322 can be any existing type; its specific structure will not be described in detail here.

[0055] like Figure 6 As shown, the feeding mechanism 330 includes a feeding fixing frame 331, which is connected to the machine base 100. A feeding motor 332 and two feeding driven wheels 333 are mounted on the feeding fixing frame 331, with the two driven wheels 333 located at opposite ends of the feeding fixing frame 331. A feeding drive wheel 334 is mounted on the output end of the feeding motor 332. A feeding drive belt 335 is sleeved on the feeding drive wheel 334 and the feeding driven wheels 333, and a feeding push block 336 is fixedly mounted on the feeding drive belt 335. After the tissue slices are heated, the feeding lifting motor 313 drives the feeding tray 312 to descend to a height that matches the material flow channel 200. Then, the pushing motor 332 is controlled to work, driving the feeding push block 336 to move. The feeding push block 336 will connect with the material hopper on the feeding tray 312, thereby pushing the material hopper to slide on the feeding tray 312 until the material hopper carrying the tissue slices is pushed into the material flow channel 200.

[0056] In order to limit and guide the moving direction of the feeding pushing block 336, the feeding guide rail 337 is arranged on the feeding fixing frame 331, and the feeding pushing block 336 is in sliding connection with the feeding guide rail 337. When the feeding motor 332 works, the feeding pushing block 336 will slide on the feeding guide rail 337; the movement direction of the feeding pushing block 336 is limited and guided through the clamping cooperation of the two, the stability of the feeding process is improved, and it is ensured that the feeding pushing block 336 can push the hopper into the hopper flow channel 200.

[0057] During processing, the hopper containing the tissue slice is placed on the feeding tray 312 by artificial. The feeding lifting motor 313 is started, the feeding lifting screw 314 drives the feeding lifting sliding block 315 and the lifting plate 316 to ascend, so that the feeding tray 312 carrying the hopper enters the baking oven 322 to be heated. After heating, the feeding lifting motor 313 is reversed, so that the hopper is lowered to the initial position. The feeding motor 332 is started, the feeding driving belt 335 drives the feeding pushing block 336 to move along the feeding guide rail 337, and the hopper is pushed from the feeding tray 312 into the hopper flow channel 200, so that the feeding process is completed.

[0058] As shown in Figure 7 The hopper flow channel 200 is provided with the blocking mechanism 220 and the positioning mechanism 230 at positions corresponding to each second processing position 500; the blocking mechanism 220 is used for blocking the sliding of the hopper in the hopper flow channel 200, and the positioning mechanism 230 is used for limiting the position of the hopper in the hopper flow channel 200 at a position corresponding to the second processing position 500.

[0059] During actual processing, the feeding and warming mechanism 300 will deliver the hopper to the first second processing position 500 in the hopper flow channel 200, and then the corresponding hopper pushing mechanism 210 will push the hopper to slide to the second second processing position 500; at the same time, the feeding and warming mechanism 300 will deliver the second hopper to the first second processing position 500 in the hopper flow channel 200; and so on, until all the second processing positions 500 are pushed to the hopper.

[0060] In the above pushing process, the blocking mechanism 220 corresponding to the frontmost second processing position 500 will work first to block the hopper at the frontmost second processing position 500; after the hopper is in place, the positioning mechanism 230 corresponding to the frontmost second processing position 500 will work to limit the hopper on the hopper flow channel 200 corresponding to the second processing position 500. After the hopper at the frontmost second processing position 500 is pushed into place, the blocking mechanism 220 corresponding to the next second processing position 500 will work, and after the hopper is in place, the positioning mechanism 230 of the second processing position 500 will work to limit and fix the hopper on the hopper flow channel 200 corresponding to the second processing position 500. In this way, all the positioning mechanisms 230 limit and fix the respective hoppers on the corresponding second processing positions 500, thus completing the process of moving the hoppers in the hopper flow channel 200.

[0061] In order to limit the sliding process of the hopper, two hopper limiting plates 240 are fixed parallelly on both sides of the upper end face of the hopper flow channel 200 by bolts. The distance between the two hopper limiting plates 240 is slightly greater than the width of the hopper, thereby playing a guiding and anti-overturning role for the movement of the hopper.

[0062] As shown in Figure 8 The hopper pushing mechanism 210 is located on one side or below the hopper flow channel 200. The hopper pushing mechanism 210 includes a pushing fixed frame 211 fixed on the machine table 100 by bolts. The pushing fixed frame 211 is provided with a hopper pushing motor 212, a hopper pushing driven wheel 213, and a pushing guide rail 214. A hopper pushing driving wheel 215 is installed on the output shaft of the hopper pushing motor 212. A hopper pushing transmission belt 216 is sleeved on the hopper pushing driving wheel 215 and the hopper pushing driven wheel 213. A hopper pushing sliding block 217 is fixedly installed on the hopper pushing transmission belt 216 and is in sliding and clamping cooperation with the pushing guide rail 214. A hopper pushing block 218 is fixedly installed on the hopper pushing sliding block 217 and can extend out of the upper surface of the hopper flow channel 200 and abut against the side or end of the hopper. By controlling the hopper pushing motor 212 to work, the hopper pushing sliding block 217 and the hopper pushing block 218 can be driven to move along the pushing guide rail 214 through the hopper pushing transmission belt 216, thereby pushing the hopper in the hopper flow channel 200 and realizing the function of pushing the hopper from the previous processing position to the next processing position.

[0063] Through the sliding cooperation of the hopper pushing sliding block 217 and the pushing guide rail 214, the movement direction of the hopper pushing block 218 can be limited and guided, ensuring that it can push the hopper to slide in the hopper flow channel 200.

[0064] As shown in Figure 9As shown, the blocking mechanism 220 includes a blocking lifting module, in this embodiment, the blocking lifting module is a vertically installed blocking electric push rod 221. The blocking electric push rod 221 is fixed on the pushing fixed frame 211, the output end of the blocking electric push rod 221 penetrates through a pre-set through hole on the flow channel, and is connected with a wedge-shaped or square blocking block 222. After all the second processing positions 500 on the front are pushed to the silo, the control system will automatically control the blocking electric push rod 221 of the next second processing position 500 to act, push the blocking block 222 to rise and protrude from the upper surface of the silo flow channel 200, and just block the forward path of the next silo, so that it stops on the silo flow channel 200 corresponding to the second processing position 500. When the silo needs to be released, the electric push rod is retracted, driving the blocking block 222 to descend below the plane of the silo flow channel 200, and the silo can continue to move forward.

[0065] As shown in the figure, Figure 9 As shown, the positioning mechanism 230 includes a positioning lifting module, in this embodiment, the positioning lifting module adopts a vertically installed positioning electric push rod 231. The positioning electric push rod 231 is fixed on the pushing fixed frame 211, the output end of the positioning electric push rod 231 upward, and the output end of the positioning electric push rod 231 is provided with two positioning pins 232; in other embodiments, the number of positioning pins 232 can also be any other number. Correspondingly, the bottom of the silo 600 is processed with a positioning hole 603 matched with the shape of the positioning pin 232. When the silo is stopped by the blocking mechanism 220, the control system instructs the positioning electric push rod 231 to act, pushes the mounting block and the positioning pin 232 to rise, so that the two positioning pins 232 are accurately inserted into the positioning hole at the bottom of the silo, thereby constraining the silo in horizontal and vertical directions, realizing accurate positioning and locking, and ensuring that the liquid injection mechanism 800 and the waste liquid recovery mechanism 900 can perform dyeing operation on the tissue slices in the silo. After processing is completed, the positioning electric push rod 231 is retracted, driving the positioning pin 232 to descend and separate from the silo, and the locking is released.

[0066] In other embodiments, the blocking lifting module and the positioning lifting module can also adopt other linear driving devices such as air cylinders, motor lead screws and the like.

[0067] It should be noted that a positioning device is also provided at a position corresponding to the first processing position 700 on the machine table 100, and the positioning device has the same structure and function as the above-mentioned positioning mechanism 230.

[0068] As shown in the figure, Figure 10 As shown in the figure, the dyeing mounting frame 1000 is fixedly installed on the machine table 100, and all the liquid injection mechanisms 800 and the waste liquid recovery mechanisms 900 are installed on the dyeing mounting frame 1000.

[0069] The liquid injection mechanism 800 comprises a liquid injection transverse movement module 810, which is fixedly connected with the dyeing mounting frame 1000. An output end of the liquid injection transverse movement module 810 is provided with a liquid injection lifting mounting plate 820. The liquid injection lifting mounting plate 820 is provided with a liquid injection lifting module 830 and a needle tube cleaning assembly 840. An output end of the liquid injection lifting module 830 is provided with a liquid injection needle 850. One end of the liquid injection needle 850 is connected with a liquid injection pump. The liquid injection transverse movement module 810 is used to drive the liquid injection needle 850 to move along the length direction of the material bin, so that the liquid injection needle 850 can be aligned with each material groove in the material bin respectively. The liquid injection lifting module 830 can drive the liquid injection needle 850 to descend or ascend. Through cooperation of the liquid injection transverse movement module 810 and the liquid injection lifting module 830, the liquid injection needle 850 can be driven to extend into each material groove of the material bin respectively, so as to facilitate dyeing of the tissue slices in each material groove. The liquid injection needle 850 can inject the liquid medicine into the material groove through the connected liquid injection pump, so that the liquid medicine can dye the tissue slices in the material bin. The liquid injection lifting module 830 can also drive the liquid injection needle 850 to be connected with the needle tube cleaning assembly 840. The needle tube cleaning assembly 840 is used to clean the liquid injection needle 850. Cleaning the liquid injection needle 850 can avoid mutual influence of different liquid medicines, so that the liquid injection mechanism 800 can be used for liquid injection work of different liquid medicines, and the versatility of the equipment is improved.

[0070] As shown in Figure 11 The liquid injection transverse movement module 810 comprises a liquid injection transverse movement fixing seat 811, which is connected with the dyeing mounting frame 1000. The liquid injection transverse movement fixing seat 811 is provided with a lead screw assembly (not shown in the figure) and a liquid injection transverse movement motor 812. An output end of the liquid injection transverse movement motor 812 is connected with the lead screw assembly. The liquid injection transverse movement fixing seat 811 is slidingly provided with a liquid injection transverse movement sliding block 813, which is connected with the lead screw assembly. In work, the lead screw assembly is driven to rotate by the liquid injection transverse movement motor 812, and then drives the liquid injection transverse movement sliding block 813 to slide transversely on the liquid injection transverse movement fixing seat 811. The liquid injection transverse movement sliding block 813 drives the liquid injection lifting mounting plate 820, the liquid injection lifting module 830 and the liquid injection needle 850 to move synchronously, so as to drive the liquid injection needle 850 to move to the top of each material groove in the material bin respectively.

[0071] As shown in Figures 12-13As shown, the liquid injection lifting module 830 includes a liquid injection lifting motor 831 fixedly connected with a liquid injection lifting mounting plate 820, the liquid injection lifting mounting plate 820 is provided with a liquid injection lifting driven wheel 832, the output end of the liquid injection lifting motor 831 is provided with a liquid injection lifting driving wheel 833, the liquid injection lifting driving wheel 833 and the liquid injection lifting driven wheel 832 are sleeved with a liquid injection lifting transmission belt 834, the liquid injection lifting transmission belt 834 is provided with a liquid injection lifting sliding block 835, and the liquid injection needle 850 is connected with the liquid injection lifting sliding block 835. In work, the liquid injection lifting motor 831 works to drive the liquid injection lifting driving wheel 833 to rotate, drive the liquid injection lifting transmission belt 834 to move, drive the liquid injection lifting sliding block 835 and the liquid injection needle 850 to move synchronously, so that the liquid injection needle 850 extends into or out of the trough in the material bin.

[0072] In order to limit and guide the direction of the lifting movement of the liquid injection needle 850, the liquid injection lifting mounting plate 820 is provided with a liquid injection lifting guide rail 836, and the liquid injection lifting sliding block 835 is slidably connected with the liquid injection lifting guide rail 836. When the liquid injection lifting motor 831 works, the liquid injection lifting sliding block 835 is driven to move; the liquid injection lifting sliding block 835 is constrained by the liquid injection lifting guide rail 836 and can only slide in the direction of the liquid injection lifting guide rail 836, thereby driving the liquid injection needle 850 to accurately insert into the trough to complete the liquid injection.

[0073] In order to improve the control accuracy, the liquid injection lifting mounting plate 820 is provided with a position sensor 837, and the liquid injection lifting sliding block 835 is provided with a detection tab 838 which can be in contact with the position sensor 837. Under normal circumstances, the detection tab 838 is separated from the position sensor 837; when liquid injection is needed, the liquid injection lifting motor 831 drives the liquid injection lifting sliding block 835 to descend, thereby driving the liquid injection needle 850 to descend synchronously; with the descent of the liquid injection lifting sliding block 835, the detection tab 838 on the liquid injection lifting sliding block 835 will be in contact with the position sensor 837, at this time, the liquid injection needle 850 has also been inserted into the trough of the material bin, and the position sensor 837 will feed back a signal to the controller of the automatic dyeing machine, and the controller will immediately control the liquid injection lifting motor 831 to stop working. Through the cooperation of the detection tab 838 and the position sensor 837, the liquid injection needle 850 can be accurately inserted into the trough, avoiding the problems of breaking the liquid injection needle 850 or inserting through the material bin due to too much insertion, and also avoiding the problem of inaccurate liquid injection due to insufficient insertion.

[0074] In order to facilitate cleaning of the injection needle 850, in the embodiment, the lower end surface of the injection needle 850 is a sealed structure, and the liquid outlet hole of the injection needle 850 is arranged on the side wall of the injection needle 850. Arranging the liquid outlet hole on the side wall of the injection needle 850 can prevent the drug solution from dripping when the injection needle 850 is lifted, avoid pollution of adjacent tanks or equipment, and improve the cleanliness of operation; on the other hand, when cleaning, the cleaning liquid can be injected into the injection needle 850 through the liquid outlet hole, so as to clean the inside of the injection needle 850.

[0075] Specifically, as shown in Figure 14 The needle cleaning assembly 840 includes a cleaning mounting bracket 841 fixedly connected with the injection lifting mounting plate 820. The cleaning mounting bracket 841 is provided with a cleaning tank 842 made of flexible material (such as silica gel). The cleaning tank 842 is provided with a needle passing hole 843 penetrating through the upper and lower end surfaces, and the injection needle 850 can pass through the needle passing hole 843 and gap-fit with the needle passing hole 843. When injecting, the injection needle 850 extends into the tank in the material bin after passing through the needle passing hole 843. The side wall of the cleaning tank 842 is provided with a water inlet connector 844 and a water outlet connector 845, both of which are in communication with the needle passing hole 843. The water inlet connector 844 is connected with the cleaning liquid, and the water outlet connector 845 is connected with a negative pressure suction device.

[0076] When cleaning is needed, the injection horizontal movement module 810 and the injection lifting module 830 move cooperatively to insert the injection needle 850 into the needle passing hole 843 of the cleaning tank 842. The cleaning liquid is injected into the cleaning tank 842 through the water inlet connector 844, and the cleaning liquid flowing through the outer wall of the injection needle 850 can clean the outer wall thereof; at the same time, because the liquid outlet hole of the injection needle 850 is on the side wall, some cleaning liquid will flow into the inside of the injection needle 850 through the liquid outlet hole, so as to clean the inside of the injection needle 850. At the same time, the water outlet connector 845 generates negative pressure suction force through the external negative pressure suction device, so as to suck away the waste liquid generated in the cleaning tank 842, avoiding overflow of the cleaning liquid.

[0077] When working, the material bin pushing mechanism 210 or the material pushing mechanism 410 pushes the material bin containing the tissue slices to the injection position. The injection horizontal movement motor 812 is controlled to work, the injection horizontal movement slider 813 is driven to move through the screw assembly, the injection needle 850 is aligned with one of the tanks in the material bin, the injection lifting motor 831 drives the injection lifting slider 835 to move downward through the transmission belt, and the injection needle 850 is inserted into the tank. The injection pump is started, the drug solution is injected into the tank through the liquid outlet hole on the side wall of the injection needle 850, the injection lifting module 830 lifts the injection needle 850 after the injection is completed, and then the drug solution fully contacts the tissue slices in the tank, so as to realize the purpose of dyeing the tissue slices in the material bin.

[0078] AsFigure 10 As shown, the waste liquid recovery mechanism 900 includes a recovery transverse module 910, which is fixedly connected to the dyeing mounting frame 1000. The output end of the recovery transverse module 910 is provided with a recovery lifting module 920, and the output end of the recovery lifting module 920 is provided with a liquid extraction needle 930 and an air blowing assembly 940. The liquid extraction needle 930 is externally connected to a negative pressure suction device, and the air blowing assembly 940 is externally connected to an air source. During processing, after the drug solution in the material tank has stained the tissue section, the cooperation of the recovery horizontal movement module 910 and the recovery lifting module 920 drives the liquid extraction needle 930 to be inserted into the corresponding material tank. The negative pressure generated by the negative pressure suction device connected to the liquid extraction needle 930 draws away the waste liquid in the material tank. At the same time, the cooperation of the recovery horizontal movement module 910 and the recovery lifting module 920 drives the air blowing component 940 to move directly above each material tank in the material box flow channel. The air blowing component 940 blows air into the material tank to form a directional airflow, which drives the waste liquid remaining on the side wall of the material tank to gather towards the liquid extraction needle 930, so that the liquid extraction needle 930 can completely draw out the waste liquid in the material tank, effectively solving the problem of incomplete suction caused by liquid surface tension or liquid adhesion.

[0079] The recovery transverse movement module 910 has the same structure as the liquid injection transverse movement module 810, so the specific structure of the recovery transverse movement module 910 will not be described in detail in this article.

[0080] like Figures 15-16 As shown, the recovery lifting module 920 includes a recovery lifting mounting plate 921, which is connected to the output end of the recovery horizontal movement module 910. A recovery lifting motor 922 and a freely rotatable recovery lifting driven wheel 923 are mounted on the recovery lifting mounting plate 921. A recovery lifting drive wheel 924 is mounted on the output shaft of the recovery lifting motor 922. A recovery lifting transmission belt 925 is fitted onto the recovery lifting drive wheel 924 and the recovery lifting driven wheel 923. A recovery lifting slider 926 is fixedly mounted on the recovery lifting transmission belt 925; a liquid extraction needle 930 and an air blowing assembly 940 are respectively connected to the recovery lifting slider 926. When the recycling transverse module 910 drives the air blowing assembly 940 and the liquid extraction needle 930 to move directly above the material trough, the recycling lifting motor 922 is controlled to work. The recycling lifting motor 922 drives the recycling lifting slider 926 to move vertically through belt drive, thereby driving the liquid extraction needle 930 to insert into the corresponding material trough, so as to facilitate the extraction of waste liquid in the material trough. At the same time, the air blowing assembly 940 moves to the top of the material trough to facilitate air blowing into the material trough.

[0081] To limit and guide the direction of the lifting motion, a retrieval lifting guide rail 927 is fixedly installed on the retrieval lifting mounting plate 921, and the retrieval lifting slider 926 is slidably engaged with the retrieval lifting guide rail 927. When the retrieval lifting motor 922 is working, it can drive the retrieval lifting slider 926 to slide on the retrieval lifting guide rail 927. Through the sliding engagement between the retrieval lifting slider 926 and the retrieval lifting guide rail 927, the lifting direction of the suction needle 930 can be limited and guided to ensure smooth lifting motion.

[0082] To position the descent stroke of the suction needle 930, a second sensor 928 is installed on the recovery lifting mounting plate 921, and a second sensing tab 929 is installed on the recovery lifting slider 926. The second sensing tab 929 can connect with the second sensor 928. Normally, the second sensing tab 929 and the second sensor 928 are in a separate state. When waste liquid needs to be recovered, the recovery lifting motor 922 drives the recovery lifting slider 926 to descend, causing the suction needle 930 and the air blowing assembly 940 to descend synchronously. As the recovery lifting slider 926 descends, the second sensing tab 929 on the recovery lifting slider 926 will connect with the second sensor 928. At this time, the suction needle 930 has just been inserted into the material trough of the hopper, and the air blowing assembly 940 has just moved to the air blowing position above the hopper. The second sensor 928 will send a feedback signal to the control center of the automatic dyeing machine. The control center will then immediately control the recovery lifting motor 922 to stop working. The cooperation between the second sensing lever 929 and the second sensor 928 enables the liquid extraction needle 930 to be accurately inserted into the material trough, while simultaneously driving the air blowing assembly 940 to the air blowing position, thereby improving the stability of the processing and the accuracy of the control.

[0083] In actual operation, when the recovery transverse module 910 drives the suction needle 930 and the air blowing assembly 940 to move along the length of the material box, they may overlap with the position of the injection mechanism 800. Therefore, to avoid motion interference, a avoidance rotary motor 950 is installed on the recovery lifting slider 926. A rotary mounting block 960 is connected to the output end of the avoidance rotary motor 950, and the suction needle 930 and the air blowing assembly 940 are respectively connected to the rotary mounting block 960. During processing, if the position of the suction needle 930 and the air blowing assembly 940 overlaps with the injection needle 850 on the injection mechanism 800, the avoidance rotary motor 950 can drive the rotary mounting block 960 to rotate in the horizontal plane; this causes the suction needle 930 and the air blowing assembly 940 to rotate synchronously, thereby moving the position of the suction needle 930 and the air blowing assembly 940 away from directly above the material box, achieving avoidance and solving the problem of motion interference.

[0084] To improve the accuracy of the avoidance mechanism, a first sensor 970 is installed on the recovery lifting slider 926, and a first sensing lever 980 is fixed on the rotating mounting block 960. Normally, the first sensing lever 980 and the first sensor 970 are separate. When avoidance rotation is required, the avoidance rotation motor 950 drives the rotating mounting block 960 to rotate, causing the first sensing lever 980 to move together until it engages with the first sensor 970. The first sensor 970 then sends a feedback signal to stop the avoidance rotation motor 950. At this point, the rotating mounting block 960 has rotated by 90 degrees, precisely causing the suction needle 930 and the air blowing assembly 940 to rotate to a position misaligned with the injection needle 850 of the injection mechanism 800, thus achieving the avoidance function.

[0085] like Figure 17 As shown, the air blowing assembly 940 includes an air nozzle 941, which is fixedly mounted on the rotating mounting block 960. One end of the air nozzle 941 is connected to an external air source through a pipeline, and the other end is provided with a triangular air blowing section 942. Multiple air blowing holes 943 are provided on the end face of the air blowing section 942. During operation, the external air source supplies high-pressure gas to the air nozzle 941. The gas flows through the air nozzle 941 into each air blowing hole 943, and then blows into each material tank through each air blowing hole 943, blowing the liquid medicine in the material tank towards the liquid extraction needle 930 so that the liquid extraction needle 930 can extract all the liquid medicine.

[0086] In this embodiment, there are two extraction needles 930, which are symmetrically distributed on both sides of the air nozzle 941. The distance between the two extraction needles 930 is less than the length of the material trough, allowing both extraction needles 930 to be inserted into the same material trough simultaneously. Furthermore, by placing the two extraction needles 930 on both sides of the air nozzle 941, when the air nozzle 941 blows air into the material trough, the liquid in the trough will flow to both sides, flowing into the corresponding extraction needle 930. By using two extraction needles 930, the extraction efficiency can be improved, thereby increasing the processing efficiency.

[0087] During operation, once dyeing is completed in a particular tank, the recovery transverse module 910 is activated, moving the extraction needle 930 and air nozzle 941 directly above the tank. Subsequently, the recovery lifting motor 922 drives the recovery lifting slider 926 downwards via belt drive, lowering the extraction needle 930 and air nozzle 941 to a preset position. The negative pressure suction device is activated, drawing in waste liquid through the extraction needle 930; simultaneously, the air source supplies air to the air nozzle 941, and the airflow exits from the air blowing hole 943, agitating the waste liquid and causing it to converge towards the extraction needles 930 on both sides, ensuring thorough suction. After suction is complete, the recovery lifting module 920 rises, and the recovery transverse module 910 moves to the next tank position, repeating the above process until all tanks are processed.

[0088] During the process of pumping waste liquid, if it is necessary to avoid the injection needle 850 of the injection mechanism 800, the avoidance rotary motor 950 is controlled to drive the rotary mounting block 960 to rotate, so that the pumping needle 930 and the air nozzle 941 are deviated from the upper part of the silo flow channel 200 to achieve avoidance.

[0089] like Figures 18-19 As shown, the discharge pushing mechanism 410 includes a discharge pushing frame 411 fixedly mounted on the machine base 100, and a discharge driving mechanism is mounted on the discharge pushing frame 411. In this embodiment, the discharge driving mechanism includes a discharge motor 412 fixedly mounted on the discharge pushing frame 411, and a discharge driving wheel 413 is mounted on the output shaft of the discharge motor 412. Discharge driven wheels 414 are also mounted at both ends of the discharge pushing frame 411. A discharge transmission belt 415 is sleeved on the discharge driving wheel 413 and the two discharge driven wheels 414. A discharge pushing block 416 is fixedly connected to the discharge transmission belt 415. During processing, the material hopper channel 200 can transport the material hopper containing the tissue slices to the connection position between the material hopper channel 200 and the discharge channel 420; the discharge motor 412 drives the discharge drive wheel 413 to rotate, which in turn drives the discharge transmission belt 415 to drive the discharge push block 416 to move. The discharge push block 416 pushes the material hopper to slide within the material hopper channel 200 and the discharge channel 420, realizing the function of feeding and unloading materials to the first processing position 700.

[0090] In other embodiments, the discharge drive mechanism may also employ other linear drive devices such as a lead screw structure, an electric cylinder, or a pneumatic cylinder.

[0091] To ensure smooth movement of the discharge push block 416, a discharge guide rail 417 is installed on the discharge push frame 411, and a discharge slider 418 is installed at the bottom of the discharge push block 416. The discharge slider 418 is slidably engaged with the discharge guide rail 417, allowing the discharge push block 416 to reciprocate linearly along the discharge guide rail 417. The cooperation between the discharge guide rail 417 and the discharge slider 418 limits and guides the movement direction of the discharge push block 416, improving the accuracy and stability of the processing.

[0092] Two push blocks 419 are hinged to the discharge push block 416, located at opposite ends of the discharge push block 416. Each push block 419 can swing around its hinge point, passing through both the hopper flow channel 200 and the discharge flow channel 420, with one end passing through each channel abutting against the side wall of the hopper. A push limit post 440 is also fixedly installed on the discharge push block 416. The push limit post 440 restricts the swing angle of the push block 419 to only one direction, ensuring that the push block 419 maintains reliable contact with the hopper side wall when pushing the hopper. When the push block 419 encounters an obstacle during its return stroke, it can rotate and swing to avoid it.

[0093] Initially, the discharge pusher block 416 is located on the discharge channel 420, meaning the two pusher blocks 419 are located between the first processing position 700 and the hopper channel 200. During processing, when the hopper channel 200 transports the hopper to the position where it connects with the discharge channel 420, the discharge motor 412 is first controlled to drive the discharge pusher block 416 towards the hopper channel 200. The discharge pusher block 416 drives the pusher blocks 419 to move. After the pusher blocks 419 move and connect with the hopper in the hopper channel 200, the lower end face of the hopper will press against the pusher blocks 419, causing them to rotate and swing along the hinge, allowing the pusher blocks 419 to pass through the bottom surface of the hopper until they move to the other side of the hopper in the hopper channel 200. Then, the discharge motor 412 is controlled to reverse, driving the discharge pusher block 419 to move towards the hopper channel 200. The moving block 416 drives the pushing block 419 to move towards the discharge end 421 of the discharge channel 420. The discharge pushing block 416 drives the pushing block 419 to move synchronously. One end of the pushing block 419 extending into the hopper channel 200 will abut against the hopper in the hopper channel 200. At this time, the other end of the pushing block 419 will abut against the pushing limit post 440. Due to the constraint of the pushing limit post 440, the pushing block 419 cannot rotate or swing. It can only push the hopper from the hopper channel 200 into the discharge channel 420 until it slides to the position of the first processing position 700, thus completing the feeding work of the first processing position 700. Then, the tissue sections in the hopper on the first processing station 700 are stained by the liquid injection mechanism 800 and the waste liquid recovery mechanism 900. After the first processing station 700 is completed, the discharge motor 412 drives the pusher block 419 to push the hopper to slide on the discharge channel 420 until the hopper slides to the discharge end 421 of the discharge channel 420, thus completing the discharge of the hopper.

[0094] Two hopper guide blocks are fixed parallel to each other on the upper surface of the discharge channel 420. The distance between the two hopper guide blocks is slightly greater than the length of the hopper. The hopper guide blocks can guide the hopper to slide on the discharge channel 420 and prevent it from deviating, thereby improving the stability of the operation.

[0095] like Figure 20As shown, processing blocking mechanisms 430 are respectively provided at positions corresponding to the first processing station 700 on the machine tool 100. The processing blocking mechanism 430 can abut against the hopper on the discharge channel 420 to limit the hopper to the position on the discharge channel 420 corresponding to the first processing station 700. Specifically, the processing blocking mechanism 430 includes two blocking mounting seats 431 symmetrically fixed on both sides of the discharge channel 420. Each blocking mounting seat 431 is equipped with a blocking drive push rod 432. The output end of the blocking drive push rod 432 faces the center of the discharge channel 420, and an intercepting block 433 is installed on the output end of the blocking drive push rod 432. When it is necessary to feed material to the first processing station 700, the blocking drive push rod 432 can drive the intercepting block 433 to extend above the discharge channel 420. At this time, the hopper can be blocked by the intercepting block 433, limiting it to the position of the first processing station 700, thus achieving precise feeding to the first processing station 700. Once the first processing station 700 has completed its processing, the blocking drive push rod 432 can be used to drive the intercepting block 433 to retract and release the material from the hopper.

[0096] The present invention has the following beneficial effects:

[0097] 1. Fully Automated Multi-Station Parallel Processing: Through the coordinated operation of the feeding and heating mechanism 300, the material hopper channel 200, multiple processing stations, and the discharge mechanism 400, a fully automated production line operation is achieved for tissue sections, from heating and multi-station staining to discharge. Multiple processing stations can perform staining operations simultaneously, significantly improving the equipment's throughput and staining efficiency, making it suitable for large-volume sample processing.

[0098] 2. Improved staining quality and consistency: The use of a precise injection mechanism 800 and a waste liquid recovery mechanism 900 ensures the accuracy and consistency of drug addition and waste liquid extraction, reduces human error, and improves the reliability and repeatability of staining results.

[0099] 3. High degree of automation and reduced human intervention: From feeding, heating, conveying, positioning, liquid injection, waste liquid extraction to discharge, all operations are automated, which greatly reduces the labor intensity of operators, reduces reliance on skilled workers, and also reduces the risk of biological sample contamination.

[0100] 4. Optimized structural design and high space utilization: Through the ingenious design of the hopper flow channel 200, the pushing mechanism and the positioning and blocking mechanism, the orderly and accurate transmission and positioning of the hopper in a limited space is realized. The equipment has a compact structure and reasonable layout.

[0101] 5. Self-cleaning function to prevent cross-contamination: The injection mechanism 800 integrates a needle cleaning component 840, which can automatically clean the injection needle 850 before and after injection or when changing the drug solution, effectively preventing cross-contamination between different drugs and ensuring dyeing quality.

[0102] 6. Thorough waste liquid recovery: The waste liquid recovery mechanism 900 is equipped not only with a liquid extraction needle 930, but also with an air blowing component 940. The waste liquid remaining at the bottom of the material tank can be blown towards the liquid extraction needle 930 by air blowing, ensuring that the waste liquid is completely recovered and creating good conditions for the next dyeing step.

[0103] 7. Reliable operation and strong adaptability: Each module adopts mature drive methods such as motors and modules, ensuring precise and reliable movement. The articulated pusher block 419 design of the discharge push mechanism 410 allows it to push and return to its original position for obstacle avoidance in unidirectional movement, resulting in a simple and practical structure.

[0104] The above-described specific embodiments are preferred embodiments of the present invention and are not intended to limit the specific scope of the present invention. The scope of the present invention includes but is not limited to the specific embodiments described herein. All equivalent changes made in accordance with the present invention are within the protection scope of the present invention.

Claims

1. A multi-station fully automatic HE dyeing machine, characterized in that: The machine includes a feeding and heating mechanism, a hopper channel, and a discharging mechanism. One end of the hopper channel is connected to the feeding and heating mechanism, and the other end is connected to the discharging mechanism. The feeding and heating mechanism is used to heat the tissue slices in the hopper and transport the heated hopper into the hopper channel; The machine platform is provided with multiple second processing positions at the corresponding positions of the hopper flow channel, and the hopper flow channel is provided with multiple hopper pushing mechanisms, which are used to push the hopper to slide on the hopper flow channel; The discharge mechanism includes a discharge pushing mechanism and a discharge channel mounted on the machine platform. One end of the discharge channel is the discharge end, and the other end is connected to the hopper channel. A first processing position is provided in the middle of the discharge channel. The discharge pushing mechanism is connected to the hopper channel and the discharge channel respectively. The discharge pushing mechanism can push the hopper in the hopper channel to the first processing position, and can also push the hopper on the first processing position to the unloading end. The machine platform is equipped with a liquid injection mechanism and a waste liquid recovery mechanism at the corresponding positions of the first processing position and each of the second processing positions. The liquid injection mechanism is used to inject liquid medicine into the hopper, and the waste liquid recovery mechanism is used to remove the waste liquid from the hopper. The machine is equipped with a dyeing mounting frame. The liquid injection mechanism includes a liquid injection transverse movement module, which is connected to the dyeing mounting frame. The output end of the liquid injection transverse movement module is equipped with a liquid injection lifting mounting plate. The liquid injection lifting mounting plate is equipped with a liquid injection lifting module and a needle cleaning assembly. The output end of the liquid injection lifting module is equipped with a liquid injection needle. One end of the liquid injection needle is externally connected to a liquid injection pump. The liquid injection transverse movement module and the liquid injection lifting module can drive the liquid injection needle to extend into each material trough of the hopper. The liquid injection lifting module can also drive the liquid injection needle to connect with the needle cleaning assembly, which is used to clean the liquid injection needle. The lower end face of the injection needle is a sealed structure, and the liquid outlet of the injection needle is located on the side wall of the injection needle; The syringe cleaning assembly includes a cleaning mounting frame, which is connected to the liquid injection lifting mounting plate. The cleaning mounting frame is provided with a cleaning tank, and the cleaning tank has a needle hole that passes through the upper and lower end faces of the cleaning tank. The liquid injection needle can pass through the needle hole and is in clearance fit with the needle hole. The side wall of the cleaning tank is provided with a water inlet connector and a water outlet connector. The water inlet connector and the water outlet connector are respectively connected to the needle hole. The water inlet connector is connected to the cleaning liquid, and the water outlet connector is connected to the negative pressure suction device. The waste liquid recovery mechanism includes a recovery transverse module connected to the dyeing mounting frame. The output end of the recovery transverse module is equipped with a recovery lifting module, and the output end of the recovery lifting module is equipped with a liquid extraction needle and an air blowing assembly. The liquid extraction needle is externally connected to a negative pressure suction device, and the air blowing assembly is externally connected to an air source. The recovery transverse module and the recovery lifting module can drive the liquid extraction needle to extend into each material trough of the hopper, and the air blowing assembly is used to blow air into the material trough.

2. The multi-station fully automatic HE dyeing machine according to claim 1, characterized in that: The feeding and heating mechanism includes a feeding mechanism, a baking oven, and a feeding and pushing mechanism, which are respectively installed on the machine platform; The feeding mechanism includes a feeding lifting module connected to the machine base. The output end of the feeding lifting module is equipped with a feeding tray for placing a hopper containing tissue sections. The feeding lifting module can drive the feeding tray to move up and down, thereby causing the hopper to extend into or out of the baking oven. The baking oven is used to heat the tissue sections in the hopper. The feeding pushing mechanism is connected to the feeding mechanism and the hopper flow channel respectively, and is used to push the hopper on the feeding tray into the hopper flow channel.

3. The multi-station fully automatic HE dyeing machine according to claim 1, characterized in that: The material hopper flow channel is provided with a blocking mechanism and a positioning mechanism at positions corresponding to each of the second processing positions. The blocking mechanism is used to prevent the material hopper from sliding in the material hopper flow channel, and the positioning mechanism is used to limit the material hopper to the position corresponding to the second processing position in the material hopper flow channel.

4. The multi-station fully automatic HE dyeing machine according to claim 1, characterized in that: The hopper pushing mechanism includes a pushing fixed frame connected to the machine base. The pushing fixed frame is equipped with a hopper pushing motor and a hopper pushing driven wheel. The output end of the hopper pushing motor is equipped with a hopper pushing driving wheel. A hopper pushing transmission belt is sleeved on the hopper pushing driving wheel and the hopper pushing driven wheel. A hopper pushing slider is equipped on the hopper pushing transmission belt. A hopper pushing block is equipped on the hopper pushing slider. The hopper pushing block can abut against the hopper in the hopper flow channel.

5. The multi-station fully automatic HE dyeing machine according to claim 1, characterized in that: The output end of the recovery lifting module is equipped with a positioning rotary motor, and the output end of the positioning rotary motor is equipped with a rotary mounting block. The positioning rotary motor can drive the rotary mounting block to rotate, and the liquid suction needle and the air blowing assembly are respectively connected to the rotary mounting block.

6. The multi-station fully automatic HE dyeing machine according to claim 1, characterized in that: The air blowing assembly includes an air nozzle, which is connected to the output end of the recovery lifting module. One end of the air nozzle is connected to an external air source, and the other end is provided with a triangular air blowing part. The end face of the air blowing part is provided with multiple air blowing holes. There are two liquid extraction needles, and the two liquid extraction needles are symmetrically distributed on both sides of the air nozzle. The distance between the two liquid extraction needles is less than the length of the material trough.

7. The multi-station fully automatic HE dyeing machine according to any one of claims 1-6, characterized in that: The discharge pushing mechanism includes a discharge pushing frame, which is connected to the machine base. The discharge pushing frame is equipped with a discharge motor. The output end of the discharge motor is equipped with a discharge drive wheel. The two ends of the discharge pushing frame are respectively equipped with discharge driven wheels. A discharge transmission belt is fitted on the discharge drive wheel and the discharge driven wheel. A discharge pushing block is provided on the discharge transmission belt. The discharge pushing block is provided with a pushing block, which can pass through the hopper channel and the discharge channel respectively. The pushing block is hinged to the discharge pushing block and can swing around the hinge point as the axis. The discharge pushing block is provided with a pushing limiting post, which can abut against the pushing limiting post.

Citation Information

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