Intelligent heparin sodium production crushing device

Abstract

The application belongs to the technical field of crushing, and particularly relates to an intelligent crushing equipment for heparin sodium production, which comprises a supporting structure, a crusher is arranged at one side of the upper end of the supporting structure, a protection mechanism is arranged at the upper end of the crusher, a guide mechanism is arranged at the lower end outlet of the crusher, a conveying mechanism is arranged at one end of the supporting structure, and a grinding mechanism is arranged at the upper end of the conveying mechanism. The equipment is provided with the grinding mechanism, the grinding static disc is connected with the sleeve on the fixing ring through the air cylinder, the air cylinder piston rod can drive the grinding static disc to slide up and down, the gap between the grinding static disc and the grinding dynamic disc is adjusted in real time, the design can accurately control the grinding granularity, the needs of different fine processing stages of heparin sodium raw materials can be met, and excessive grinding or insufficient grinding is avoided; the air cylinder can adjust the pressure of the grinding static disc on the raw materials, cooperates with the rotation of the grinding dynamic disc, realizes the double grinding effect of extrusion and shearing on the raw materials, and improves the grinding efficiency and uniformity.

Description

Technical Field

[0001] This invention relates to the field of pulverization technology, and in particular to an intelligent pulverization device for the production of heparin sodium. Background Technology

[0002] Sodium heparin is a natural anticoagulant drug extracted from animal viscera (such as pig intestinal mucosa and bovine lungs). Its production process has extremely high requirements for the safety, efficiency and precision of raw material crushing.

[0003] In heparin sodium production, the raw material grinding process has long faced technical challenges such as insufficient safety protection, process blockage, and low grinding precision. Traditional equipment often employs fixed protection, rigid guidance, and a single grinding structure, which is difficult to adapt to the high viscosity, fibrousness, and heat sensitivity of freeze / freeze-dried raw materials: fixed baffle protection is inefficient, raw material splashing leads to a certain loss in recovery rate, and operators are exposed to a low-temperature dust environment; rigid guide plates are prone to blockage due to material adhesion, requiring frequent shutdowns for cleaning; in particular, traditional grinding mechanisms rely on fixed-gap planar stationary discs, resulting in low fiber cutting rate and uneven particle size distribution, which seriously affects subsequent extraction efficiency.

[0004] To address the above problems, this invention proposes an intelligent pulverizing device for the production of heparin sodium. Summary of the Invention

[0005] Based on the existing technical problems of safety and raw material waste, process blockage and low efficiency, and insufficient grinding precision in heparin sodium production equipment, this invention proposes an intelligent pulverizing equipment for heparin sodium production.

[0006] The present invention proposes an intelligent pulverizing equipment for the production of heparin sodium, comprising a support structure, a pulverizer being provided at the upper end of one side of the support structure, a protective mechanism being provided at the upper end of the pulverizer, a guiding mechanism being provided at the lower outlet of the pulverizer, a conveying mechanism being provided at one end of the support structure, and a grinding mechanism being provided at the upper end of the conveying mechanism.

[0007] The protective mechanism is designed to prevent the raw material from splashing out during the initial crushing of the frozen heparin sodium raw material block.

[0008] The guiding mechanism is used to guide the heparin sodium raw material after preliminary crushing to the conveying mechanism.

[0009] The conveying mechanism is used to transport the heparin sodium raw material after it has been initially crushed.

[0010] The grinding mechanism is designed to perform fine processing on the heparin sodium raw material after it has been initially pulverized.

[0011] Preferably, the protective mechanism includes a motor disposed on one side of the support structure, a transmission system disposed on one side of the motor, the transmission system including a chain, both ends of the chain being meshed with spur gears, one side of one of the spur gears being fixedly connected to the output shaft of the motor, and one side of the other spur gear being fixedly connected to a rotating rod, one side of the rotating rod being rotatably connected to the outer side of the crusher via a bearing, and one end of the rotating rod being fixedly connected to a protective plate, the lower end of the protective plate being convex.

[0012] Preferably, the guiding mechanism includes a baffle fixedly connected to the lower end of the crusher. A bearing is embedded within the baffle's plate array. The outer sides of the inner rings of two adjacent bearings are rotatably connected to a connecting rod via a pin. A gear set is provided on the outer side of one of the bearings. The gear set includes a meshing gear one and a gear two. One side of gear two is rotatably connected to the side of the connecting rod via a pin. The other side of gear two is fixedly connected to the outer side of the inner ring of one of the bearings. Adjacent connecting rods are rotatably connected via pins. A spur gear two is fixedly connected to the outer side of gear one. A motor two is provided on one side of spur gear two. The housing of motor two is fixedly connected to the support leg of the supporting structure. A guide plate is provided between the two baffles. The inner side of the inner ring of each bearing one is rotatably connected to the side of the guide plate via a bearing. A guide chamber is provided at one end of the baffle, and one end of the guide plate is located inside the guide chamber.

[0013] Preferably, the conveying mechanism includes a fixed tube fixed to one side of the support structure, a conveying roller is provided inside the fixed tube, an actuating device is provided at the upper end of the conveying roller, a sealed bearing is rotatably connected to the lower end of the conveying roller, the outer side of the sealed bearing is fixedly connected to the inner wall of the fixed tube, a bevel gear set is provided at the lower end of the sealed bearing, one bevel gear of the bevel gear set is fixedly connected to the inner ring of the sealed bearing, the other bevel gear of the bevel gear set is rotatably connected to the tube body of the fixed tube through a bearing, a rotating shaft is fixedly connected to the outer side of the inner ring of the bearing, a fixed rod is rotatably connected to one end of the rotating shaft through a bearing, one end of the fixed rod is fixedly connected to the lower end of the support leg of the support structure, a toothed ring is fixedly sleeved on the outer surface of the rotating shaft, the outer diameter of the toothed ring is the same as the outer diameter of the second spur gear, and a chain is provided between the toothed ring and the second spur gear.

[0014] Preferably, the actuating device includes a radially nested bearing assembly, which is composed of a large bearing and a small bearing nested together. The inner ring of the large bearing is fixedly connected to the outer ring of the small bearing. A spur gear three is provided at the upper end of the connection between the inner ring of the large bearing and the outer ring of the small bearing. A spur gear four meshes with the surface of the spur gear three. The lower surface of the spur gear four is fixedly connected to the upper end of the conveying roller through a cylinder. A fixing cap is fixedly connected to the upper end of the outer ring of the large bearing. The inner wall of the fixing cap is provided with a locking tooth that matches the surface of the spur gear three. The inner wall of the fixing cap meshes with the surface of the spur gear three. A paddle is fixedly connected to the outer surface of the fixing cap.

[0015] Preferably, the grinding mechanism includes a motor three mounted on one side of a motor three, a spur gear five fixedly connected to one end of the output shaft of the motor three, a fixed ring fixedly sleeved on the upper outer surface of the fixed tube, a protective tube mounted on the upper end of the fixed ring, a connecting block fixedly connected to the lower end of one side of the protective tube, the lower end of the connecting block fixedly connected to the upper surface of the support structure, the tube body of the protective tube being divided into upper and lower parts, a bearing three being disposed between the upper and lower parts of the protective tube, the upper and lower parts of the protective tube being fixedly connected to the outer ring of the bearing three respectively, an annular groove being formed on the inner wall of the lower part of the protective tube, and a grinding moving disc being movably sleeved on the outer side of the fixed tube, the grinding moving disc rotating within the annular groove.

[0016] Preferably, the outer surface of the grinding disc is toothed, the lower part of the protective tube has a slot, the toothed surface of the grinding disc meshes with the toothed surface of the spur gear five, the upper side of the grinding disc is fixedly connected to the inner ring of the bearing three, the upper end of the grinding disc is shaped like a chamfered pyramid, a grinding stationary disc is slidably sleeved on the outer surface of the fixed tube, the grinding stationary disc is located directly above the fixed ring, a sealing coating is applied to the contact surface between the grinding stationary disc and the fixed tube, sleeves are fixedly connected in an array on the outer side of the fixed ring, a cylinder is respectively installed inside each sleeve, the piston rod of each cylinder is fixedly connected to the lower surface of the grinding stationary disc, a guide ring is fixedly sleeved on the outer surface of the fixed tube, the guide ring is located below the fixed ring, and an outlet is opened on one side of the guide ring.

[0017] Preferably, the upper surface of the grinding disc has a radial pattern.

[0018] Preferably, the surface of the guide plate is coated with edible oil.

[0019] The beneficial effects of this invention are as follows:

[0020] 1. By setting up a protective mechanism, the motor drives the chain and spur gear transmission system to drive the rotating protective plate to form a dynamic barrier. The raised lower end effectively blocks and guides splashed materials. Compared with traditional fixed baffles, the splash prevention efficiency is improved and the raw material recovery rate is increased. Dynamic protection reduces human contact, avoids low temperature freezing and dust hazards, meets GMP clean requirements, and has a compact structure that is suitable for production lines, improving the safety and continuity of the crushing process.

[0021] 2. By setting up a guiding mechanism, a reciprocating swing guide plate with gear linkage is adopted, combined with a food-grade edible oil coating, to reduce the adhesion rate and blockage risk of frozen scraps; at the same time, rigid gear transmission ensures that the guide plates on both sides swing synchronously, and works with the semi-enclosed guide chamber to achieve precise material collection.

[0022] 3. By setting up a conveying mechanism, synchronous driving of the conveying roller and the guide plate is achieved, eliminating synchronization errors of multiple motors and reducing energy consumption; the radial nested bearing group of the actuation device improves the frozen pellet breakage rate and reduces the fiber entanglement rate.

[0023] 4. By setting up a grinding mechanism, the grinding stationary disc is connected to the sleeve 65 on the fixed ring via a cylinder. The cylinder piston rod can drive the grinding stationary disc to slide up and down, adjusting the gap between the grinding stationary disc and the grinding moving disc in real time. This design can precisely control the grinding particle size to meet the needs of different fine processing stages of heparin sodium raw materials and avoid over-grinding or under-grinding. The cylinder can adjust the pressure of the grinding stationary disc on the raw material, which, together with the rotation of the grinding moving disc, achieves a dual grinding effect of squeezing and shearing on the raw material, improving grinding efficiency and uniformity. The upper and lower parts of the protective tube are connected by a bearing three-way connection, and the upper end of the grinding moving disc is fixed to the inner ring of the bearing three-way connection, ensuring the coaxiality and stability of the grinding moving disc when it rotates at high speed, reducing mechanical wear, and not affecting the grinding effect on the raw material. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of an intelligent pulverizing device for producing heparin sodium according to the present invention;

[0025] Figure 2 This is a diagram showing the position of the motor in an intelligent heparin sodium production pulverizing device proposed in this invention.

[0026] Figure 3 This is a front view of the rotating rod of an intelligent pulverizing device for producing heparin sodium proposed in this invention;

[0027] Figure 4 This is a perspective view of the guiding mechanism of an intelligent pulverizing device for producing heparin sodium proposed in this invention;

[0028] Figure 5 This is a diagram showing the position of the guide plate in an intelligent heparin sodium production pulverizing device proposed in this invention.

[0029] Figure 6 This is a cross-sectional view of the fixed tube of an intelligent heparin sodium production pulverizing device proposed in this invention;

[0030] Figure 7 This is a cross-sectional view of the fixed cap of an intelligent heparin sodium production pulverizing device proposed in this invention;

[0031] Figure 8 This is a diagram showing the position of the grinding disc in an intelligent pulverizing device for producing heparin sodium, as proposed in this invention.

[0032] Figure 9 This is a three-dimensional view of the grinding disc of an intelligent pulverizing device for producing heparin sodium proposed in this invention;

[0033] Figure 10 This is a three-dimensional view of the guide ring of an intelligent pulverizing device for producing heparin sodium proposed in this invention;

[0034] Figure 11 This is a three-dimensional view of the grinding disc of an intelligent pulverizing device for producing heparin sodium proposed in this invention;

[0035] Figure 12 This is a cross-sectional view of the protective tube of an intelligent heparin sodium production pulverizing device proposed in this invention.

[0036] In the diagram: 1. Support structure; 2. Crusher; 3. Protective mechanism; 31. Motor 1; 32. Transmission system; 33. Rotating rod; 34. Protective plate; 4. Guide mechanism; 41. Baffle; 42. Bearing 1; 43. Connecting rod; 44. Gear set; 45. Spur gear 2; 46. Motor 2; 47. Guide plate; 48. Guide chamber; 5. Conveying mechanism; 51. Fixed pipe; 52. Conveying roller; 53. Actuating device; 531. Radial nested shaft 532. Spur Gear III; 533. Spur Gear IV; 534. Fixing Cap; 54. Bevel Gear Set; 55. Sealed Bearing; 56. Rotating Shaft; 57. Chain II; 58. Fixing Rod; 6. Grinding Mechanism; 60. Motor III; 61. Spur Gear V; 62. Grinding Moving Disc; 63. Grinding Stationary Disc; 64. Fixing Ring; 65. Sleeve; 66. Cylinder; 67. Guide Ring; 68. Bearing III; 69. Protective Tube; 610. Connecting Block. Detailed Implementation

[0037] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments.

[0038] Reference Figures 1-12An intelligent pulverizing device for producing heparin sodium includes a support structure 1, a pulverizer 2 is provided at the upper end of one side of the support structure 1, a protective mechanism 3 is provided at the upper end of the pulverizer 2, a guiding mechanism 4 is provided at the lower outlet of the pulverizer 2, a conveying mechanism 5 is provided at one end of the support structure 1, and a grinding mechanism 6 is provided at the upper end of the conveying mechanism 5.

[0039] The protective mechanism 3 is designed to prevent the frozen blocks of heparin sodium from splashing out during the initial crushing process. The protective mechanism 3 uses a physical barrier to prevent the frozen blocks from splashing during the initial crushing process, thereby avoiding waste of raw materials and the risk of contact with operators, while also reducing workshop cleaning costs.

[0040] The guiding mechanism 4 is designed to guide the heparin sodium raw material after preliminary crushing to the conveying mechanism 5. The guiding mechanism 4 stably introduces the preliminary crushed raw material into the conveying mechanism 5 to prevent outlet blockage caused by irregular particles after crushing, ensure process continuity, and reduce the frequency of downtime for cleaning.

[0041] The conveying mechanism 5 is used to transport the heparin sodium raw material after preliminary crushing. The conveying mechanism 5 is precisely connected with the guiding mechanism 4 and the grinding mechanism 6. The material flow is stabilized through frequency conversion control, which avoids overload or idling of the grinding mechanism 6 due to conveying fluctuations and improves the overall equipment coordination efficiency.

[0042] The grinding mechanism 6 is designed to perform fine processing on the heparin sodium raw material after initial crushing. The grinding mechanism 6 achieves fine grinding through adjustable gap, avoiding clogging problems caused by single small-gap crushing, while meeting the stringent requirements of heparin sodium raw material for particle size uniformity.

[0043] In this embodiment, the protective mechanism 3 includes a motor 31 disposed on one side of the support structure 1. A transmission system 32 is disposed on one side of the motor 31. The transmission system 32 includes a chain 1, and spur gears are respectively meshed at both ends of the chain 1. One side of one spur gear is fixedly connected to the output shaft of the motor 31, and a rotating rod 33 is fixedly connected to one side of the other spur gear. One side of the rotating rod 33 is rotatably connected to the outer side of the crusher 2 through a bearing. A protective plate 34 is fixedly connected to one end of the rotating rod 33, and the lower end of the protective plate 34 is convex.

[0044] Specifically, motor 31 drives rotating rod 33 through chain 1 and spur gear transmission system 32, causing protective plate 34 to rotate around the outer side of crusher 2 at a constant speed, forming a ring-shaped dynamic protective barrier that continuously blocks the feed inlet or crushing chamber opening area of ​​crusher 2. The lower end of protective plate 34 is convex. During the crushing process of crusher 2, protective plate 34 is pressed down appropriately according to the degree of crushing of raw materials, thereby further ensuring the fullness of crushing.

[0045] In this embodiment, the guide mechanism 4 includes a baffle 41 fixedly connected to the lower end of the crusher 2. Bearings 42 are embedded within the baffle 41's plate array. The outer sides of the inner rings of two adjacent bearings 42 are rotatably connected to a connecting rod 43 via pins. A gear set 44 is provided on the outer side of one of the bearings 42. The gear set 44 includes a meshing gear 1 and a gear 2. One side of gear 2 is rotatably connected to the side of the connecting rod 43 via a pin, and the other side of gear 2 is fixedly connected to the outer side of the inner ring of one of the bearings 42. The adjacent connecting rods 43 are rotatably connected by a pin. A spur gear 45 is fixedly connected to the outer side of the gear one. A motor 46 is provided on one side of the spur gear 45. The housing of the motor 46 is fixedly connected to the support leg of the support structure 1. A guide plate 47 is provided between the two baffles 41. The inner side of the inner ring of each bearing 42 is rotatably connected to the side of the guide plate 47 through the bearing. A guide chamber 48 is provided at one end of the baffle 41. One end of the guide plate 47 is located inside the guide chamber 48. The surface of the guide plate 47 is coated with edible oil.

[0046] Specifically, adjacent connecting rods 43 are rotatably connected by pins, so that multiple sets of guide plates 47 form a flexible curved guide channel, similar to a wave-shaped guide groove, which can conform to the irregular discharge direction of the crusher 2 outlet and concentrate the scattered material to the central area of ​​the guide chamber 48; the surface of the guide plate 47 is coated with food-grade edible oil, such as soybean oil, to form a 0.1-0.3mm lubricating film, which can effectively prevent the fragments from adhering to the guide plate 47 due to moisture absorption, especially for the small amount of moisture contained on the surface of the heparin sodium frozen block after crushing; with the swinging motion of the guide plate 47, the adhering fine particles will fall off under the action of inertia, reducing the frequency of manual cleaning.

[0047] In this embodiment, the conveying mechanism 5 includes a fixed tube 51 fixed to one side of the support structure 1. A conveying roller 52 is provided inside the fixed tube 51. An actuating device 53 is provided at the upper end of the conveying roller 52. A sealed bearing 55 is rotatably connected to the lower end of the conveying roller 52. The outer side of the sealed bearing 55 is fixedly connected to the inner wall of the fixed tube 51. A bevel gear set 54 is provided at the lower end of the sealed bearing 55. One bevel gear of the bevel gear set 54 is fixedly connected to the inner ring of the sealed bearing 55. The other bevel gear of the bevel gear set 54 is rotatably connected to the tube body of the fixed tube 51 through a bearing. A rotating shaft 56 is fixedly connected to the outer side of the inner ring of the bearing. A fixed rod 58 is rotatably connected to one end of the rotating shaft 56 through a bearing. One end of the fixed rod 58 is fixedly connected to the lower end of the support leg of the support structure 1. A toothed ring is fixedly sleeved on the outer surface of the rotating shaft 56. The outer diameter of the toothed ring is the same as the outer diameter of the second spur gear 45. A chain 57 is provided between the toothed ring and the second spur gear 45.

[0048] Specifically, the spur gear 45 of the guide mechanism is connected to the gear ring of the conveying mechanism by the chain 2 57, so that the swing frequency of the guide plate 47 is forced to synchronize with the rotation speed of the conveying roller 52, which solves the synchronization error problem of traditional multi-motor drive and avoids material accumulation caused by the mismatch between the guide plate 47 flow speed and the conveying speed. The actuating device 53 at the upper end of the conveying roller 52 rotates with the roller body, pushing the initially crushed frozen block along the inner wall of the fixed tube 51 to the grinding mechanism 6, and at the same time, it peels off the adhering fragments. In particular, the mechanical actuation of the actuating device 53 can prevent the connective tissue fibers that may exist in the heparin sodium raw material from wrapping the fibers around the roller body.

[0049] In this embodiment, the actuating device 53 includes a radially nested bearing assembly 531, which is composed of a large bearing and a small bearing nested together. The inner ring of the large bearing is fixedly connected to the outer ring of the small bearing. A spur gear 3 532 is provided at the upper end of the connection between the inner ring of the large bearing and the outer ring of the small bearing. A spur gear 4 533 meshes with the surface of the spur gear 3 532. The lower surface of the spur gear 4 533 is fixedly connected to the upper end of the conveying roller 52 through a cylinder. A fixing cap 534 is fixedly connected to the upper end of the outer ring of the large bearing. The inner wall of the fixing cap 534 is provided with a locking tooth that matches the surface of the spur gear 3 532. The inner wall of the fixing cap 534 meshes with the surface of the spur gear 3 532. A paddle is fixedly connected to the outer surface of the fixing cap 534.

[0050] Specifically, the outer surface of the paddle is coated with a Teflon coating with a thickness of 50-100μm. Combined with the centrifugal force generated by its rotation, the adhering wet material is detached in a very short time. For long fibers that may be present in the heparin sodium raw material, the edge cutting effect of the paddle during rotation can cut the fibers, reduce the entanglement rate, and avoid the decrease in conveying efficiency caused by fiber entanglement. A labyrinth seal is used between the large and small bearings and filled with food-grade silicone grease to prevent bearing lubricant from seeping into the raw material channel.

[0051] In this embodiment, the grinding mechanism 6 includes a motor 60 disposed on one side of a motor 31. A spur gear 61 is fixedly connected to one end of the output shaft of the motor 60. A fixing ring 64 is fixedly sleeved on the upper outer surface of the fixing tube 51. A protective tube 69 is disposed on the upper end of the fixing ring 64. A connecting block 610 is fixedly connected to the lower end of one side of the protective tube 69. The lower end of the connecting block 610 is fixedly connected to the upper surface of the support structure 1. The tube body of the protective tube 69 is divided into upper and lower parts. A bearing 68 is disposed between the upper and lower parts of the protective tube 69. The upper and lower parts of the protective tube 69 are respectively fixedly connected to the outer ring of the bearing 68. An annular groove is formed on the inner wall of the lower part of the protective tube 69. A grinding disc 62 is movably sleeved on the outer side of the fixing tube 51. The grinding disc 62 rotates within the annular groove. The outer side of the grinding disc 62 is provided with teeth. The lower part of the protective tube 69 has a slot. The toothed surface of the grinding disc 62 meshes with the toothed surface of the spur gear 61. The upper side of the grinding disc 62 is fixedly connected to the inner ring of the bearing 68. The upper end of the grinding disc 62 is shaped like a chamfered pyramid. The outer surface of the fixed tube 51 is slidably fitted with a grinding stationary disc 63. The grinding stationary disc 63 is located directly above the fixed ring 64. The contact surface between the grinding stationary disc 63 and the fixed tube 51 is coated with a sealing coating. The outer side of the fixed ring 64 is fixedly connected with an array of sleeves 65. Each sleeve 65 is equipped with a cylinder 66. The piston rod of each cylinder 66 is fixedly connected to the lower surface of the grinding stationary disc 63. The outer surface of the fixed tube 51 is fixedly fitted with a guide ring 67. The guide ring 67 is located below the fixed ring 64. One side of the guide ring 67 has an outlet.

[0052] Specifically, the grinding stationary disc 63 is connected to the sleeve 65 on the fixed ring 64 via a cylinder 66. The piston rod of the cylinder 66 can drive the grinding stationary disc 63 to slide up and down, adjusting the gap between the grinding stationary disc 63 and the grinding moving disc 62 in real time. This design can precisely control the grinding particle size to meet the needs of different fine processing stages of heparin sodium raw materials, avoiding over-grinding or under-grinding. The cylinder 66 can adjust the pressure of the grinding stationary disc 63 on the raw material, which, in conjunction with the rotation of the grinding moving disc 62, achieves a dual grinding effect of squeezing and shearing on the raw material, improving grinding efficiency and uniformity. The upper and lower parts of the protective tube 69 are connected by a bearing 68, and the upper end of the grinding moving disc 62 is fixed to the inner ring of the bearing 68, ensuring the coaxiality and stability of the grinding moving disc 62 when rotating at high speed, reducing mechanical wear, and not affecting the grinding effect on the raw material. The guide ring 67 outside the fixed tube 51 is located below the fixed ring 64. During the grinding process, buffer solution is added into the protective tube 69 to form a slurry. Its outlet can guide the ground material to the subsequent process, avoiding material accumulation in the grinding area and ensuring the continuity of the production process.

[0053] In this embodiment, the upper surface of the grinding disc 63 has a radial pattern.

[0054] Specifically, the centrifugal force generated by the rotation of the grinding disc 62 causes the material to move towards the edge of the grinding disc 63, and the radial pattern guides the material to move along a spiral path, extending the residence time in the grinding zone. To address the potential particle size unevenness in freeze-dried raw materials, the pattern guides large particles to concentrate in the high-shear zone, achieving gradient grinding. Small particles pass quickly along the grooves of the pattern, while large particles are repeatedly broken by the edges of the pattern.

[0055] Reference Figures 1-12 A processing method for a pulverizing equipment used in the production of heparin sodium, the specific steps of which are as follows:

[0056] Step 1: The freeze-dried block raw material is conveyed to the crusher 2 via a conveyor belt. Before starting the crusher 2, the motor 31 is turned on. The motor 31 drives the protective plate 34 at one end of the rotating rod 33 to rotate through the transmission system 32. The lower end of the protective plate 34 moves closer to the crushing area of ​​the crusher 2 until the lower end of the protective plate 34 contacts the freeze-dried block or the upper surface of the protective plate 34 is parallel to the upper surface of the crusher 2. Then the crusher 2 is turned on to crush the freeze-dried block.

[0057] Step 2: Next, turn on motor 2 (46) and motor 3 (60). The crushed material falls onto the upper surface of guide plate 47. Motor 2 (46) drives gear set 44 to rotate through spur gear 2 (45). The small gear in gear set 44 drives bearing 1 (42) to rotate, which in turn drives connecting rod 43 to rotate at a small angle. The synchronous rotation of multiple bearings 1 (42) causes guide plate 47 to move in a small-angle wave-like motion between baffles 41. The undulating guide plate 47 guides the crushed material on its upper surface to guide chamber 48. The material enters fixed tube 51 through guide chamber 48. Conveyor roller 52 is driven by chain 2 (57) and rotates through shaft 56. The rotating conveyor roller 52 conveys the crushed material to the top of fixed tube 51. Conveyor roller 52 drives spur gear 4 (533) to rotate. Spur gear 4 (533) drives fixed cap 534 to rotate through spur gear 3 (532). The rotating fixed cap 534 drives the paddle to paddle the crushed material.

[0058] Step 3: The crushed material falling into the protective tube 69 slides along the chamfered face of the grinding disc 62 toward the center of the grinding disc 62. The motor 60 drives the grinding disc 62 to rotate inside the protective tube 69 through the spur gear 61. The crushed material falls through the gap between the grinding disc 62 and the fixed tube 51 into the space between the grinding disc 62 and the grinding stationary disc 63. The gap between the grinding stationary disc 63 and the grinding disc 62 is adjusted by the cylinder 66 to further grind the crushed material. During the grinding process, buffer solution is added along the chamfered face of the grinding disc 62 to finally obtain the grinding liquid.

[0059] Step 4: The grinding slurry flows into the guide ring 67 through the gap between the raised grinding stationary disc 63 and the protective tube 69. The inclined guide ring 67 guides the grinding slurry out through the outlet for subsequent experiments.

[0060] The above description is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and inventive concept of the present invention, should be covered within the scope of protection of the present invention.

Claims

1. An intelligent pulverizing device for producing heparin sodium, comprising a support structure (1), wherein a pulverizer (2) is provided at the upper end of one side of the support structure (1), characterized in that: The upper end of the crusher (2) is provided with a protective mechanism (3), the lower end of the crusher (2) is provided with a guide mechanism (4), one end of the support structure (1) is provided with a conveying mechanism (5), and the upper end of the conveying mechanism (5) is provided with a grinding mechanism (6). The guiding mechanism (4) is used to guide the heparin sodium raw material after preliminary crushing to the conveying mechanism (5); The conveying mechanism (5) is used to convey the heparin sodium raw material after it has been initially crushed. The grinding mechanism (6) is designed to perform fine processing on the heparin sodium raw material after initial crushing. The protective mechanism (3) includes a motor (31) disposed on one side of the support structure (1). A transmission system (32) is disposed on one side of the motor (31). The transmission system (32) includes a chain. Both ends of the chain are meshed with spur gears. One side of one of the spur gears is fixedly connected to the output shaft of the motor (31). One side of the other spur gear is fixedly connected to a rotating rod (33). One side of the rotating rod (33) is rotatably connected to the outer side of the crusher (2) through a bearing. One end of the rotating rod (33) is fixedly connected to a protective plate (34). The lower end of the protective plate (34) is convex. The guiding mechanism (4) includes a baffle (41) fixedly connected to the lower end of the crusher (2). A bearing (42) is embedded in the plate array of the baffle (41). The outer sides of the inner rings of two adjacent bearings (42) are rotatably connected to a connecting rod (43) by a pin. A gear set (44) is provided on the outer side of one of the bearings (42). The gear set (44) includes a gear 1 and a gear 2 that mesh with each other. One side of the gear 2 is rotatably connected to the side of the connecting rod (43) by a pin. The other side of the gear 2 is fixedly connected to the outer side of the inner ring of one of the bearings (42). The adjacent connecting rods (43) are rotatably connected by a pin shaft. A spur gear (45) is fixedly connected to the outer side of the gear one. A motor (46) is provided on one side of the spur gear (45). The outer shell of the motor (46) is fixedly connected to the support leg of the support structure (1). A guide plate (47) is provided between the two baffles (41). The inner side of the inner ring of each bearing (42) is rotatably connected to the side of the guide plate (47) through the bearing. A guide chamber (48) is provided at one end of the baffle (41). One end of the guide plate (47) is located inside the guide chamber (48). The conveying mechanism (5) includes a fixed tube (51) fixed to one side of the support structure (1). A conveying roller (52) is provided inside the fixed tube (51). An actuating device (53) is provided at the upper end of the conveying roller (52). A sealed bearing (55) is rotatably connected to the lower end of the conveying roller (52). The outer side of the sealed bearing (55) is fixedly connected to the inner wall of the fixed tube (51). A bevel gear set (54) is provided at the lower end of the sealed bearing (55). One of the bevel gears of the bevel gear set (54) is connected to the inner ring of the sealed bearing (55). The bevel gear of the bevel gear set (54) is rotatably connected to the tube body of the fixed tube (51) through a bearing. A rotating shaft (56) is fixedly connected to the outer side of the inner ring of the bearing. A fixed rod (58) is rotatably connected to one end of the rotating shaft (56) through the bearing. One end of the fixed rod (58) is fixedly connected to the lower end of the support leg of the support structure (1). A toothed ring is fixedly sleeved on the outer surface of the rotating shaft (56). The outer diameter of the toothed ring is the same as the outer diameter of the second spur gear (45). A chain (57) is provided between the toothed ring and the second spur gear (45). The actuating device (53) includes a radially nested bearing assembly (531), which is composed of a large bearing and a small bearing nested together. The inner ring of the large bearing is fixedly connected to the outer ring of the small bearing. A spur gear three (532) is provided at the upper end of the connection between the inner ring of the large bearing and the outer ring of the small bearing. A spur gear four (533) meshes with the surface of the spur gear three (532). The lower surface of the spur gear four (533) is fixedly connected to the upper end of the conveying roller (52) through a cylinder. A fixing cap (534) is fixedly connected to the upper end of the outer ring of the large bearing. The inner wall of the fixing cap (534) is provided with a tooth that matches the surface of the spur gear three (532). The inner wall of the fixing cap (534) meshes with the surface of the spur gear three (532). A paddle is fixedly connected to the outer surface of the fixing cap (534). The grinding mechanism (6) includes a motor three (60) provided on one side of a motor one (31). One end of the output shaft of the motor three (60) is fixedly connected to a spur gear five (61). A fixing ring (64) is fixedly sleeved on the upper outer surface of the fixing tube (51). A protective tube (69) is provided on the upper end of the fixing ring (64). A connecting block (610) is fixedly connected to the lower end of one side of the protective tube (69). The lower end of the connecting block (610) is fixedly connected to the upper surface of the support structure (1). The tube body of the protective tube (69) is divided into upper and lower parts. A bearing three (68) is provided between the upper and lower parts of the protective tube (69). The upper and lower parts of the protective tube (69) are respectively fixedly connected to the outer ring of the bearing three (68). An annular groove is opened on the inner wall of the lower part of the protective tube (69). A grinding moving disc (62) is movably sleeved on the outer side of the fixing tube (51). The grinding moving disc (62) rotates in the annular groove.

2. The intelligent pulverizing equipment for producing heparin sodium according to claim 1, characterized in that: The outer surface of the grinding disc (62) is set with a toothed surface. The lower part of the protective tube (69) has a slot. The toothed surface of the grinding disc (62) meshes with the toothed surface of the spur gear five (61). The upper side of the grinding disc (62) is fixedly connected to the inner ring of the bearing three (68). The upper end of the grinding disc (62) is shaped like a chamfered pyramid. The outer surface of the fixed tube (51) is slidably fitted with a grinding stationary disc (63). The grinding stationary disc (63) is located directly above the fixed ring (64). The contact surface between the disc (63) and the fixed tube (51) is coated with a sealing coating. The outer side of the fixed ring (64) is fixedly connected with a sleeve (65). Each sleeve (65) is equipped with a cylinder (66). The piston rod of each cylinder (66) is fixedly connected to the lower surface of the grinding disc (63). A guide ring (67) is fixedly sleeved on the outer surface of the fixed tube (51). The guide ring (67) is located below the fixed ring (64). One side of the guide ring (67) has an outlet.

3. The intelligent pulverizing equipment for producing heparin sodium according to claim 2, characterized in that: The upper surface of the grinding disc (63) has a radial pattern.

4. The intelligent pulverizing equipment for producing heparin sodium according to claim 3, characterized in that: The surface of the guide plate (47) is coated with edible oil.

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