Thrombus mechanical removal catheter and device

Abstract

The invention discloses a mechanical thrombus removal catheter and device, and relates to the technical field of medical instruments. The thrombus mechanical removal catheter comprises an inner tube, an outer tube, a suction tube, a light-emitting device and an image acquisition device, the outer tube is arranged on the periphery of the inner tube in a sleeving mode, a suction channel is defined by the outer tube and the inner tube, the suction tube is arranged in the suction channel, and a liquid spraying hole is formed in the far end of the suction tube and used for spraying liquid into the suction channel to crush thrombus; the light-emitting device is arranged at the far end of the inner tube and is used for emitting light to thrombus in a blood vessel; the image acquisition device is arranged at the far end of the inner tube and is used for acquiring an image signal at the thrombus in the blood vessel; the structure of the suction catheter is improved, and thrombus is crushed and sucked away according to the Bernoulli principle; the light-emitting device and the camera are arranged to collect image signals in real time, the convenience of evaluating the thrombus position and the clearing effect by medical staff is improved, radiography radiation exposure is reduced, radiography time is shortened, and radiation damage is reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a thrombus mechanical removal catheter and device. BACKGROUND

[0002] Once formed, the thrombus in the peripheral blood vessel will slow down or block the blood flow in the peripheral blood vessel, and even migrate to other organs, leading to serious consequences. For example, common acute lower limb arterial embolism can cause lower limb ischemic necrosis, and if not treated in time, there is a risk of amputation, acute mesenteric arterial embolism can cause intestinal ischemia, intestinal perforation, intestinal necrosis, etc. If not treated effectively in the early stage, deep vein thrombosis can cause limb swelling, pain, ulceration, and thrombus sequelae. Once pulmonary embolism occurs, it is often very dangerous, and severe cases can result in sudden death.

[0003] Methods for treating peripheral vascular thrombus include anticoagulation, surgical thrombectomy, thrombolysis (catheter thrombolysis and drug thrombolysis), catheter thrombolysis, and mechanical thrombus removal. Among them, anticoagulant therapy is the standard and basic treatment method for deep vein thrombosis, using anticoagulant drugs to prevent further development of thrombosis and prevent pulmonary embolism and deep vein thrombosis and recurrence, but cannot significantly reduce the incidence of thrombosis syndrome. Surgical thrombectomy is highly efficient, but it is traumatic and can damage the venous valve, and is now less commonly used. Drug thrombolysis or catheter thrombolysis has a short treatment time and fewer complications, and is the preferred method of thrombolysis in clinical practice, but it can lead to a high risk of bleeding, especially in elderly patients, who can experience fatal cerebral hemorrhage.

[0004] In recent years, with the development of science and technology, some thrombus mechanical removal devices that utilize principles of rotational atherectomy, aspiration, fluid mechanics, and ultrasound assistance have been increasingly applied in the field of thrombus removal. For example, CN110384536B discloses a typical thrombus mechanical removal device that mainly utilizes the Bernoulli principle of fluid mechanics to inject high-pressure saline into a jet pipe, reverse the saline into the catheter lumen at the distal end of the jet pipe, and spray high-speed saline at the jet port to break the thrombus, then generate a significant negative pressure at the backflow port to suck the broken thrombus into the outflow cavity for further crushing and discharge. This method can effectively remove thrombus in the peripheral blood vessel, has fewer complications, causes less trauma, has a shorter operation time, and has a good prognosis. However, the thrombus mechanical removal device cannot view the thrombus removal status in real time during the operation, and continuous contrast assessment of thrombus removal effect is required, which can cause significant radiation damage to the doctor. SUMMARY

[0005] The main purpose of the present application is to provide a thrombus mechanical removal catheter and device, which aims to improve the convenience of medical staff in assessing the position and removal effect of thrombus, reduce the radiation exposure of contrast, reduce the contrast time, and reduce the radiation damage.

[0006] To achieve the above object, the present application provides a thrombus mechanical removal catheter, comprising:

[0007] an inner tube;

[0008] an outer tube, sleeved on the outer periphery of the inner tube and surrounding the inner tube to form a suction channel, a distal end of the outer tube being provided with a jet port and a suction port respectively communicating with the suction channel, the jet port being used for jetting liquid to the thrombus in the blood vessel, and the suction port being used for sucking the thrombus into the suction channel under the action of negative pressure;

[0009] a suction tube, provided in the suction channel, a distal end of the suction tube being provided with a plurality of liquid jet holes, and a proximal end of the suction tube being adapted to be connected to a suction device, the liquid jet holes being used for jetting liquid into the suction channel to crush the thrombus;

[0010] a light emitting device, provided at the distal end of the inner tube and used for emitting light to the thrombus in the blood vessel; and

[0011] an image collecting device, provided at the distal end of the inner tube and used for collecting image signals of the thrombus in the blood vessel.

[0012] Optionally, the inner tube is provided with a fiber cavity and first and second light transmission ports communicating with the fiber cavity, the light emitting device comprises a fiber, a half mirror and a full mirror, the half mirror and the full mirror are arranged in the distal end of the fiber in a spaced manner, the half mirror, the first light transmission port and the jet port correspond in position, and the full mirror, the second light transmission port and the suction port correspond in position.

[0013] Optionally, the inner tube is further provided with a signal line cavity, the image collecting device comprises a signal line and first and second cameras respectively connected to the signal line, the signal line is contained in the signal line cavity, and the first and second cameras are respectively arranged corresponding to the jet port and the suction port.

[0014] Optionally, the thrombus mechanical removal catheter further comprises a separator, the inner tube is provided with a separator cavity and an inlet and outlet port communicating with the separator cavity, the inlet and outlet port correspond in position to the jet port, the separator is contained in the separator cavity and can be driven by an external force to extend out of the jet port of the outer tube or retract into the separator cavity, and is used for scraping the thrombus in the blood vessel.

[0015] Optionally, the separator comprises a pushing section and a scraping section, the scraping section is connected to the pushing section, and the separator is arranged in an L shape in a natural state.

[0016] Optionally, the inner tube is provided with a guide wire cavity, and the guide wire cavity is used for passing a guide wire.

[0017] Optionally, the distal tip of the inner tube is adhesively fixed to the distal tip of the outer tube.

[0018] Optionally, the thrombus mechanical removal catheter further comprises a connecting seat formed at the proximal end of the outer tube and having a suction connecting port in communication with the proximal end of the suction tube, the suction connecting port being adapted to be connected to the suction device.

[0019] To achieve the above object, the present application further provides a thrombus mechanical removal device, comprising a suction device and a thrombus mechanical removal catheter as described above connected to the suction device, the suction device being used to deliver high-pressure fluid to the suction tube, and the thrombus mechanical removal catheter comprising:

[0020] an inner tube;

[0021] an outer tube sleeved on the outer periphery of the inner tube and surrounding the inner tube to form a suction channel, the distal end of the outer tube being provided with a jet port and a suction port in communication with the suction channel respectively, the jet port being used to jet liquid to the thrombus in the blood vessel, and the suction port being used to suck the thrombus into the suction channel under the action of negative pressure;

[0022] a suction tube provided in the suction channel, the distal end of the suction tube being provided with a plurality of liquid jet holes, the proximal end of the suction tube being adapted to be connected to the suction device, and the liquid jet holes being used to jet liquid into the suction channel to crush the thrombus;

[0023] a light emitting device provided at the distal end of the inner tube and used to emit light to the thrombus in the blood vessel; and

[0024] an image collecting device provided at the distal end of the inner tube and used to collect image signals of the thrombus in the blood vessel.

[0025] Optionally, the suction device is further used to emit light to the light emitting device and display the image signals collected by the image collecting device.

[0026] In the technical scheme of the present application, the thrombus mechanical removal catheter comprises an inner tube, an outer tube, a suction tube, a light emitting device and an image acquisition device; the outer tube is sleeved on the outer periphery of the inner tube and surrounds the inner tube to form a suction channel, the distal end of the outer tube is provided with a jet port and a suction port which respectively communicate with the suction channel, the jet port is used for jetting liquid to the thrombus in the blood vessel, and the suction port is used for sucking the thrombus into the suction channel under the action of negative pressure; the suction tube is arranged in the suction channel, the distal end of the suction tube is provided with a plurality of liquid injection holes, and the proximal end of the suction tube is adapted to be connected with a suction device, the liquid injection holes are used for jetting liquid into the suction channel to crush the thrombus; the light emitting device is arranged at the distal end of the inner tube and is used for emitting light to the thrombus in the blood vessel; and the image acquisition device is arranged at the distal end of the inner tube and is used for acquiring image signals of the thrombus in the blood vessel. It can be understood that the present application improves the structure of the suction catheter, utilizes the Bernoulli principle to crush and suck away the thrombus, acquires image signals in real time through the light emitting device and the camera arranged on the catheter, improves the convenience of medical staff in evaluating the position of the thrombus and the removal effect, reduces the radiation exposure of the contrast, reduces the contrast time, and thus reduces the radiation damage. BRIEF DESCRIPTION OF DRAWINGS

[0027] In order to more clearly illustrate the technical scheme in the embodiments of the present application or the prior art, the drawings needed to be used in the following embodiment or prior art description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor on the basis of the drawings shown.

[0028] Figure 1 It is an embodiment of the structure of the thrombus mechanical removal device of the present application.

[0029] Figure 2 It is an embodiment of the internal structure of the distal end of the catheter of the thrombus mechanical removal device of the present application.

[0030] Figure 3 It is an embodiment of the working schematic diagram of the catheter removing thrombus of the thrombus mechanical removal device of the present application.

[0031] Figure 4 It is a principle diagram of the catheter removing thrombus of an embodiment of the thrombus mechanical removal device of the present application.

[0032] Figure 5 It is an embodiment of the working schematic diagram of the catheter removing thrombus of the thrombus mechanical removal device of the present application.

[0033] Figure 6 It is a radial cross-sectional view of the distal end of the catheter of an embodiment of the thrombus mechanical removal device of the present application.

[0034] Figure 7Fig. 1 is a top view of the injection port and the suction port of the catheter in an embodiment of the thrombus mechanical removal device of the present application (when the separator is not extended);

[0035] Figure 8 Fig. 2 is a radial cross-sectional view of the distal end of the catheter in an embodiment of the thrombus mechanical removal device of the present application (when the separator is not extended);

[0036] Figure 9 Fig. 3 is an axial cross-sectional view of the distal end of the catheter in an embodiment of the thrombus mechanical removal device of the present application (when the separator is not extended);

[0037] Figure 10 Fig. 4 is a top view of the injection port and the suction port of the catheter in an embodiment of the thrombus mechanical removal device of the present application (when the separator is extended);

[0038] Figure 11 Fig. 5 is a radial cross-sectional view of the distal end of the catheter in an embodiment of the thrombus mechanical removal device of the present application (when the separator is extended);

[0039] Figure 12 Fig. 6 is an axial cross-sectional view of the distal end of the catheter in an embodiment of the thrombus mechanical removal device of the present application (when the separator is extended);

[0040] Figure 13 Fig. 7 is a structural schematic view of the separator of the catheter in an embodiment of the thrombus mechanical removal device of the present application;

[0041] Figure 14 Fig. 8 is a structural schematic view of the scraping section of the separator in an embodiment of the thrombus mechanical removal device of the present application.

[0042] Brief Description of the Drawings

[0043] 10, inner tube; 20, outer tube; 30, suction tube; 60, separator; 100a, suction channel; 20a, injection port; 20b, suction port; 30a, liquid injection hole; 10a, optical fiber cavity; 10b, signal line cavity; 10c, separator cavity; 10d, guide wire cavity; 41, optical fiber; 42, half mirror; 43, full mirror; 51, signal line; 52, first camera; 53, second camera; 10c1, inlet and outlet; 61, pushing section; 62, scraping section; 70, guide wire; 80, connecting seat; 80a, suction connecting port; 100, catheter; 200, suction device.

[0044] The implementation, functional features and advantages of the present application will be further described with reference to the embodiments and the accompanying drawings. DETAILED DESCRIPTION

[0045] With reference to the accompanying drawings, the technical solutions in the embodiments of the present application will be described clearly and completely. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all the other embodiments obtained by a person of ordinary skill in the art without creative effort are within the protection scope of the present application.

[0046] It should be noted that all the direction indications (such as up, down, left, right, front, back, etc.) in the embodiments of the present application are only used to explain the relative position relationship, movement condition, etc. between components in a certain posture (as shown in the drawings), and if the certain posture changes, the direction indications also change accordingly.

[0047] In the description of the present application, it should be noted that unless otherwise explicitly specified and limited, the terms “mounting”, “connection”, “connecting” should be understood in a broad sense, for example, can be fixed connection, can be detachable connection, or integral connection; can be mechanical connection, can be electrical connection; can be direct connection, can be indirect connection through an intermediate medium, or can be the communication inside two elements. For a person of ordinary skill in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0048] In addition, the description involving “first”, “second” and the like in the present application is only for the purpose of description, and cannot be understood as indicating or implying the relative importance of the indicated technical features or implicitly indicating the number of the indicated technical features. Therefore, the features limited by “first” and “second” can explicitly or implicitly include at least one of the features. The meaning of “and / or” appearing throughout the text is to include three parallel schemes, for example, “A and / or B” includes A scheme, or B scheme, or A and B schemes are satisfied at the same time. The technical solutions of each embodiment can be combined with each other, but it must be based on the fact that a person of ordinary skill in the art can realize it, and when the combination of technical solutions appears contradictory or unachievable, it should be considered that the combination of technical solutions does not exist, and is not within the protection scope of the present application.

[0049] The present application provides a thrombus mechanical removal catheter.

[0050] With reference to Figures 1 to 6In an embodiment of the present application, the thrombus mechanical removal catheter 100 comprises an inner tube 10, an outer tube 20, a suction tube 30, a light emitting device and an image acquisition device; the outer tube 20 is sleeved on the outer periphery of the inner tube 10 and surrounds the inner tube 10 to form a suction channel 100a, the distal end of the outer tube 20 is provided with a jet port 20a and a suction port 20b which respectively communicate with the suction channel 100a, the jet port 20a is used for jetting liquid to the thrombus in the blood vessel, and the suction port 20b is used for sucking the thrombus into the suction channel 100a under the action of negative pressure; the suction tube 30 is arranged in the suction channel 100a, the distal end of the suction tube 30 is provided with a plurality of liquid jet holes 30a, and the proximal end of the suction tube 30 is adapted to be connected to a suction device 200, the liquid jet holes 30a are used for jetting liquid into the suction channel 100a to crush the thrombus; the light emitting device is arranged at the distal end of the inner tube 10 and is used for emitting light to the thrombus in the blood vessel; and the image acquisition device is arranged at the distal end of the inner tube 10 and is used for acquiring image signals of the thrombus in the blood vessel.

[0051] In the embodiment, the suction tube 30 can be made of steel or other materials capable of bearing high-pressure liquid, which is not limited herein.

[0052] The light emitting device can adopt a light emitting structure of transmitting light emitted by an external light source through an optical fiber 41, or a light source can be directly arranged on the inner tube 10, which is not limited herein.

[0053] The image acquisition device can be a CCD camera or a CMOS image sensor, which is not limited herein.

[0054] It can be understood that the present application improves the structure of the suction catheter 100, utilizes the Bernoulli principle to crush and suck away the thrombus, acquires image signals in real time by arranging the light emitting device and the image acquisition device on the catheter 100, improves the convenience of medical staff in evaluating the position of the thrombus and the removal effect, reduces the radiation exposure of the contrast, reduces the contrast time, and thus reduces the radiation damage.

[0055] In order to enable medical staff to obtain more image information of the thrombus removal in the blood vessel and make the structure of the thrombus mechanical removal catheter 100 more compact, with reference to Figures 1 to 6 In an embodiment, the inner tube 10 is provided with a fiber cavity 10a and first and second light transmission ports which communicate with the fiber cavity 10a, the light emitting device comprises an optical fiber 41, a half mirror 42 and a full mirror 43, the half mirror 42 and the full mirror 43 are arranged at the distal end of the optical fiber 41, the half mirror 42, the first light transmission port and the jet port 20a correspond in position, and the full mirror 43, the second light transmission port and the suction port 20b correspond in position. In this way, the present application realizes the emission of light at the jet port 20a and the suction port 20b by arranging one optical fiber 41, realizes the shooting of more pictures, and ensures the compactness of the catheter 100.

[0056] The half mirror 42 can be arranged at an angle of 45° with the horizontal plane, and the full mirror 43 can also be arranged at an angle of 45° with the horizontal plane, which is not limited herein.

[0057] To obtain more thrombus removal images and further improve the compactness of the catheter 100, in the embodiment, the inner tube 10 can also be provided with a signal line cavity 10b, and the image acquisition device includes a signal line 51 and a first camera 52 and a second camera 53 connected with the signal line 51 respectively. The signal line 51 is contained in the signal line cavity 10b, and the first camera 52 and the second camera 53 are arranged corresponding to the injection port 20a and the suction port 20b respectively.

[0058] It should be noted that the light source introduced into the optical fiber 41 can be visible light or invisible light (such as invisible laser). After the light reaches the half mirror 42, 50% of the light is reflected upward from the injection port 20a to illuminate the thrombus, and the remaining 50% of the light reaches the full mirror 43 along the optical fiber 41 to illuminate the thrombus upward from the suction port 20b. The two cameras receive real-time images, and the camera line transmits electrical signals to the external device for imaging.

[0059] To further improve the thrombus removal effect and efficiency, with reference to Figure 1 , Figures 5 to 14 In an embodiment, the thrombus mechanical removal catheter 100 can also include a separator 60. The inner tube 10 is provided with a separator cavity 10c and an inlet and outlet 10c1 communicating with the separator cavity 10c. The inlet and outlet 10c1 correspond to the position of the injection port 20a. The separator 60 is contained in the separator cavity 10c and can be driven by an external force to extend out of the injection port 20a of the outer tube 20 or retract into the separator cavity 10c, for scraping the thrombus in the blood vessel.

[0060] As shown in Figures 12 to 14 In the embodiment, the separator 60 can include a pushing section 61 and a scraping section 62. The scraping section 62 is connected with the pushing section 61, and the separator 60 is arranged in an L shape in a natural state. The separator 60 can be made of nickel-titanium alloy or other materials, which is not limited herein.

[0061] During the operation, after the thrombus is removed to a certain extent, the suction device 200 can be paused, the residual thrombus position is determined by observing through the optical fiber 41 and the camera assembly, the separator 60 is pushed forward to extend to contact the residual thrombus, and the catheter 100 is pulled in and out by a short distance to drive the separator 60 to scrape the residual thrombus or loosen it to a certain extent, and then the suction device 200 is started to spray and suck.

[0062] With reference to Figures 1 to 6In an embodiment, the inner tube 10 is provided with a guide wire cavity 10d for passing the guide wire 70 to facilitate guiding the thrombus mechanical removal catheter 100 to the target position in the blood vessel.

[0063] The thrombus mechanical removal catheter 100 of the present application only needs short-time radiography during operation, and the radiography can be stopped after the guide wire 70 guides the catheter 100 to the position near the thrombus, which greatly reduces the radiography time and greatly reduces the radiation damage.

[0064] In an embodiment, the distal tip of the inner tube 10 is adhesively fixed to the distal tip of the outer tube 20. In the present application, an inner tube 10 is introduced, and the tips of the inner tube 10 and the outer tube 20 are adhesively fixed together, so that a complete cavity is formed between the outer tube 20 and the inner tube 10, and water leakage does not occur.

[0065] In order to facilitate the connection of the suction device 200 and the thrombus mechanical removal catheter 100, reference is made to Figure 1 In an embodiment, the thrombus mechanical removal catheter 100 can further include a connecting seat 80 provided at the proximal end of the outer tube 20 and formed with a suction connecting port 80a in communication with the proximal end of the suction tube 30, and the suction connecting port 80a is adapted to be connected with the suction device 200.

[0066] During operation, the catheter 100 as a whole can be rotated in the blood vessel by rotating the connecting seat 80 to adjust the orientations of the injection port 20a and the suction port 20b, to observe the thrombus in real time, determine the optimal thrombus removal position, and perform the thrombus removal operation.

[0067] In addition, reference is made to Figure 2 In some embodiments, the outer tube 20 of the thrombus mechanical removal catheter 100 of the present application is provided with only one injection port 20a, which can increase the injection pressure and enhance the thrombus removal effect. During operation, the catheter 100 can be rotated to allow the injection port 20a to face different directions to remove and suction the thrombus.

[0068] The present application further provides a thrombus mechanical removal device, reference is made to Figure 1 The thrombus mechanical removal device includes a suction device 200 and a thrombus mechanical removal catheter 100 connected with the suction device 200, the suction device 200 is used to deliver high-pressure fluid to the suction tube 30, and the specific structure of the thrombus mechanical removal catheter 100 is referred to the above-mentioned embodiments. Since the thrombus mechanical removal device of the present application includes all the schemes of all the embodiments of the above-mentioned thrombus mechanical removal catheter 100, it at least has the same technical effects as the above-mentioned thrombus mechanical removal catheter 100, which will not be described here.

[0069] As Figure 1As shown, in the embodiment, the suction device 200 can further integrate a light source and an image display device for emitting light to the light emitting device and displaying the image signal collected by the image collecting device.

[0070] The above merely describes optional embodiments of the present application, and does not limit the patent scope of the present application. Any equivalent structural transformation, direct / indirect application in other related technical fields, or the like, which is made based on the content of the present application specification and drawings, falls within the patent protection scope of the present application.

Claims

1. A thrombus mechanical removal catheter, characterized by, The thrombus mechanical removal catheter comprises an inner tube, an outer tube, a suction tube, a light emitting device, and an image collecting device. The outer tube is sleeved on the outer periphery of the inner tube and forms a suction channel with the inner tube. The distal end of the outer tube is provided with a jet port and a suction port which respectively communicate with the suction channel. The jet port is used for jetting liquid to the thrombus in the blood vessel. The suction port is used for sucking the thrombus into the suction channel under the action of negative pressure. The distal end of the suction tube is provided with a plurality of liquid jet holes.

2. The thrombus mechanical removal catheter of claim 1, wherein, The liquid jet holes are used for jetting liquid into the suction channel to crush the thrombus.

3. The thrombus mechanical removal catheter of claim 2, wherein, The light emitting device is arranged at the distal end of the inner tube and is used for emitting light to the thrombus in the blood vessel.

4. The thrombus mechanical removal catheter of claim 1, wherein, The image collecting device is arranged at the distal end of the inner tube and is used for collecting image signals of the thrombus in the blood vessel.

5. The thrombus mechanical removal catheter of claim 4, wherein, The inner tube is provided with a fiber cavity, a first light transmission port, and a second light transmission port which communicate with the fiber cavity.

6. The thrombus mechanical removal catheter of claim 1, wherein, The light emitting device comprises a fiber, a half mirror, and a full mirror.

7. The thrombus mechanical removal catheter of claim 1, wherein, The half mirror and the full mirror are arranged at the distal end of the fiber.

8. The thrombus mechanical removal catheter of claim 1, wherein, The half mirror, the first light transmission port, and the jet port correspond in position.

9. A thrombus mechanical removal device, comprising: The full mirror, the second light transmission port, and the suction port correspond in position.

10. The thrombus mechanical extraction device of claim 9, wherein, The inner tube is further provided with a signal line cavity. The image collecting device comprises a signal line and first and second cameras which are respectively connected to the signal line. The signal line is contained in the signal line cavity. The first and second cameras correspond to the jet port and the suction port respectively. The thrombus mechanical removal catheter further comprises a separator. The inner tube is provided with a separator cavity and an exit and entrance which communicate with the separator cavity. The exit and entrance correspond in position to the jet port. The separator is contained in the separator cavity and can be driven by an external force to extend out of the jet port of the outer tube or retract into the separator cavity. The separator is used for scraping the thrombus in the blood vessel. The separator comprises a pushing section and a scraping section. The scraping section is connected to the pushing section. The separator is arranged in an L shape in a natural state. The inner tube is provided with a guide wire cavity. The distal tip of the inner tube is adhesively fixed to the distal tip of the outer tube. The thrombus mechanical removal catheter further comprises a connecting seat. The connecting seat is arranged at the proximal end of the outer tube and is formed with a suction connecting port which communicates with the proximal end of the suction tube. The suction connecting port is adapted to be connected to the suction device. The suction device is used for transmitting high pressure fluid to the suction tube. The suction device is further used for emitting light to the light emitting device and displaying the image signals collected by the image collecting device.

Images