Medicinal and edible traditional Chinese medicine composition with effects of regulating immunity, relieving fatigue and relieving sore throat and preparation method of medicinal and edible traditional Chinese medicine composition

Abstract

The invention discloses a medicinal and edible traditional Chinese medicine composition with the effects of regulating immunity, relieving fatigue and relieving sore throat and a preparation method of the medicinal and edible traditional Chinese medicine composition, and belongs to the technical field of medicinal and edible traditional Chinese medicine compositions.The medicinal and edible traditional Chinese medicine composition is prepared from 100 parts of phyllanthus emblica, 30-70 parts of astragalus membranaceus, 30-70 parts of fructus lycii, 1-20 parts of platycodon grandiflorum and 1-20 parts of mint. The preparation method comprises the following steps: crushing the phyllanthus emblica, the astragalus membranaceus, the platycodon grandiflorum and the mint into coarse powder, adding an ethanol aqueous solution with the concentration of 50wt% or above, carrying out ultrasonic treatment and heating treatment, and adding water into the fructus lycii for ultrasonic treatment. According to the traditional Chinese medicine composition, radix astragali, fructus lycii, radix platycodonis and herba menthae which can synergistically regulate immunity and relieve sore-throat and moisten throat are compounded, and through an optimized extraction process, the traditional Chinese medicine composition can have good sensory quality, regulate immunity, relieve fatigue and relieve sore-throat and moisten throat.

Description

Technical Field

[0001] This invention belongs to the field of medicinal and edible herbal compositions, and particularly relates to a medicinal and edible herbal composition with the effects of regulating immunity, relieving fatigue and soothing the throat, and its preparation method. Background Technology

[0002] Existing medicinal and edible herbal combinations or beverages generally suffer from poor taste and limited functionality, making it difficult to meet consumers' dual requirements for experience and efficacy.

[0003] Phyllanthus emblica, recognized by the state as a food and medicine homology substance, is rich in active ingredients such as polyphenols and vitamin C, and has various health benefits such as clearing heat and relieving sore throat, anti-oxidation, and liver protection, making its application value significant. However, its strong sour and astringent taste and cooling properties make it unpalatable when directly used in beverages, limiting its in-depth development in food and medicine homology combinations or beverages.

[0004] Therefore, how to effectively improve the sensory quality of Phyllanthus emblica while retaining its core functional components, and how to develop novel medicinal and edible herbal compositions or beverages that are pleasant to taste, have synergistic effects, and are suitable for daily consumption by sub-healthy individuals through compounding with other functional ingredients, is a technical problem that urgently needs to be solved in this field. Summary of the Invention

[0005] To address the shortcomings of the existing technology, a medicinal and edible herbal composition with the effects of regulating immunity, relieving fatigue, and soothing the throat is provided, along with its preparation method. This medicinal and edible herbal composition uses Phyllanthus emblica, which has the effects of soothing the throat and relieving fatigue, as the main functional ingredient. It is compounded with Astragalus membranaceus, Lycium barbarum, Platycodon grandiflorus, and Citrus reticulata, which can synergistically regulate immunity, soothe the throat, and improve taste. By optimizing the extraction process, the medicinal and edible herbal composition can achieve good sensory quality and the effects of regulating immunity, relieving fatigue, and soothing the throat.

[0006] The first objective of this invention is to provide a medicinal and edible herbal composition with the effects of regulating immunity, relieving fatigue and soothing the throat. The raw materials for its preparation include, by weight, 100 parts of Phyllanthus emblica, 30-70 parts of Astragalus membranaceus, 30-70 parts of Lycium barbarum, 1-20 parts of Platycodon grandiflorus, and 1-20 parts of Mentha haplocalyx.

[0007] Its preparation method includes the following steps:

[0008] Weigh out the following ingredients by weight: Phyllanthus emblica, Astragalus membranaceus, Platycodon grandiflorus, and Mentha haplocalyx. Crush them into coarse powder, add them to an ethanol aqueous solution with a concentration of 50wt% or higher, sonicate and heat them, filter them, and obtain mixture A.

[0009] Weigh out the wolfberries by weight, add water, sonicate, filter, and obtain mixture B;

[0010] Mixing mixture A with mixture B yields the medicinal and edible herbal composition that has the effects of regulating immunity, relieving fatigue, and soothing the throat.

[0011] In the above-mentioned combination of medicinal and edible herbs, Phyllanthus emblica, as the principal herb, has high antioxidant activity, which can eliminate excess free radicals after fatigue and quickly restore energy. At the same time, it can directly act on the pharyngeal mucosa to relieve swelling and discomfort. Astragalus membranaceus and Lycium barbarum, as assistant herbs, can deeply replenish energy, enhance immunity, and fight fatigue. Astragalus membranaceus and Lycium barbarum are warm and cool, one tonifying and one clearing, to avoid causing internal heat. Lycium barbarum can nourish the yin of the liver and kidneys and neutralize the initial astringency of Phyllanthus emblica with its sweetness. Furthermore, by using the above-mentioned different processes to process different raw materials, the types and contents of active ingredients in the resulting mixture A can be effectively adjusted and enriched. Astragalus membranaceus and Lycium barbarum can form a "dual tonification of qi and yin" pattern, synergistically regulating immunity and soothing the throat. Platycodon grandiflorus and Mentha haplocalyx, as adjuvant herbs, can guide the medicine upward to the throat to enhance the throat-soothing effect, while Mentha haplocalyx brings a cooling sensation, instantly relieving dryness, itching, and burning of the throat, and enhancing the flavor profile.

[0012] In some embodiments of the present invention, the raw materials for preparation further include 1-20 parts of dried tangerine peel. Dried tangerine peel can regulate qi and strengthen the spleen, promote the absorption of nourishing components, resolve the greasiness, add fruity aroma, and neutralize the initial astringency of amla.

[0013] In some embodiments of the present invention, the raw materials for preparation further include 1 to 20 parts of licorice. The natural sweetness of licorice softens the astringency of amla, complementing the lingering sweetness and ensuring a smooth mouthfeel.

[0014] The second objective of this invention is to provide a method for preparing the above-mentioned medicinal and edible herbal composition with the effects of regulating immunity, relieving fatigue, and soothing the throat, comprising the following steps:

[0015] S1. Weigh out the following ingredients by weight: Phyllanthus emblica, Astragalus membranaceus, Platycodon grandiflorus, Mentha haplocalyx, and optionally Citrus reticulata peel and licorice root. Crush them into coarse powder, add them to an ethanol aqueous solution with a concentration of 50wt% or higher, sonicate and heat them, filter them, and obtain mixture A.

[0016] S2. Weigh the wolfberries according to the weight, add water, sonicate, filter, and obtain mixture B;

[0017] S3. Mix mixture A and mixture B to obtain the medicinal and edible herbal composition.

[0018] In some embodiments of the present invention, in S1 and / or S2, a concentration step is further included after the filtration step.

[0019] In some embodiments of the present invention, in S1, the concentration of the ethanol aqueous solution is 50wt% to 90wt%.

[0020] In some embodiments of the present invention, in S1, the ratio of the amount of the ethanol aqueous solution to the amount of the coarse powder is 3~20L:1Kg.

[0021] In some embodiments of the present invention, in S1, the frequency of the ultrasound is 15~40kHz.

[0022] In some embodiments of the present invention, in S1, the heating temperature is 50~85°C.

[0023] In some embodiments of the present invention, in S1, the processing time is 30 minutes to 6 hours.

[0024] In some embodiments of the present invention, in S2, the ratio of water to wolfberry is 3~15L:1Kg.

[0025] In some embodiments of the present invention, in S2, the frequency of the ultrasound is 15~40kHz.

[0026] In some embodiments of the present invention, S2 further includes a heating step in the ultrasonic treatment process.

[0027] In some embodiments of the present invention, in S2, the duration of the ultrasonic treatment is 20 minutes to 5 hours.

[0028] In some embodiments of the present invention, in S2, the heating temperature during the ultrasonic treatment process is 35~100°C.

[0029] The third objective of this invention is to provide a preparation having the effects of regulating immunity, relieving fatigue, and soothing the throat, comprising the above-mentioned medicinal and edible herbal composition having the effects of regulating immunity, relieving fatigue, and soothing the throat, and pharmaceutically acceptable excipients or food-acceptable excipients.

[0030] In some embodiments of the present invention, the pharmaceutically acceptable excipients include at least one of diluents, humectants, binders, disintegrants, preservatives, lubricants, surfactants, and penetration enhancers.

[0031] In some embodiments of the present invention, the acceptable excipients in the food include at least one of antioxidants, flavor enhancers, preservatives, sweeteners, thickeners, emulsifiers, stabilizers, and food flavorings.

[0032] In some embodiments of the present invention, the dosage form of the formulation includes granules or liquid dosage forms.

[0033] In some embodiments of the present invention, the preparation is a liquid beverage or a solid beverage.

[0034] Compared with the prior art, the present invention has the following beneficial effects:

[0035] 1) The raw materials for the preparation of the medicinal and edible herbal composition of the present invention are reasonably matched, and the principal, assistant and adjuvant drugs work together to obtain good sensory quality, as well as good effects of regulating immunity, relieving fatigue and soothing the throat.

[0036] 2) The medicinal and edible herbal composition of the present invention uses different processes to process different raw materials, which can effectively adjust and enrich the types and contents of its active ingredients, thereby forming a "dual tonification of qi and yin" pattern, synergistically regulating immunity and soothing the throat;

[0037] 3) The medicinal and edible herbal composition of the present invention can be made into solid or liquid form, and can be used to prepare beverages that have both good taste and health benefits. Detailed Implementation

[0038] To enable those skilled in the art to better understand the technical solutions of this invention, the technical solutions of this invention will be clearly and completely described below in conjunction with the embodiments of this invention. Obviously, the described embodiments are only some embodiments of this invention, and not all embodiments. Based on the embodiments of this invention, all other embodiments obtained by those skilled in the art without creative effort should fall within the scope of protection of this invention.

[0039] Unless otherwise specified, all raw materials used in this invention are commercially available.

[0040] Preparation Example 1

[0041] This preparation example provides a medicinal and edible composition with the effects of regulating immunity, relieving fatigue, and soothing the throat. By weight, the raw materials are 100 parts of Phyllanthus emblica, 30 parts of Astragalus membranaceus, 70 parts of Lycium barbarum, 10 parts of Platycodon grandiflorus, and 10 parts of Mentha haplocalyx. The preparation method is as follows:

[0042] Step (1): Weigh out the following ingredients by weight: Phyllanthus emblica, Astragalus membranaceus, Platycodon grandiflorus, and Mentha haplocalyx. Crush them into coarse powder. Add 50wt% ethanol aqueous solution at a ratio of 13L / 1Kg of coarse powder. Sonicate at 30kHz and heat at 70℃ for 2 hours. Filter and concentrate to 1 / 13 of the original volume to obtain mixture A.

[0043] Step (2): Weigh the wolfberries according to the weight, add water at a rate of 8L / 1Kg of wolfberries, treat with 30kHz ultrasound at room temperature for 2 hours, filter, and concentrate to 1 / 8 of the original volume to obtain mixture B;

[0044] Step (3): Mix mixture A and mixture B to obtain the medicinal and edible homologous composition.

[0045] Preparation Example 2

[0046] This preparation example provides a food-medicine homologous composition with the effects of regulating immunity, relieving fatigue, and soothing the throat. By weight, the raw materials are 100 parts of Phyllanthus emblica, 50 parts of Astragalus membranaceus, 50 parts of Lycium barbarum, 10 parts of Platycodon grandiflorus, and 10 parts of Mentha haplocalyx. The preparation method is as follows:

[0047] Step (1): Weigh out the following ingredients by weight: Phyllanthus emblica, Astragalus membranaceus, Platycodon grandiflorus, and Mentha haplocalyx. Crush them into coarse powder. Add 70wt% ethanol aqueous solution at a ratio of 10L / 1Kg of coarse powder. Sonicate at 30kHz and heat at 60℃ for 2 hours. Filter and concentrate to 1 / 10 of the original volume to obtain mixture A.

[0048] Step (2): Weigh the wolfberries according to the weight parts, add water according to the amount of 10L / 1Kg wolfberries, sonicate at 30kHz and heat at 60℃ for 2 hours, filter, concentrate to 1 / 10 of the original volume to obtain mixture B;

[0049] Step (3): Mix mixture A and mixture B to obtain the medicinal and edible homologous composition.

[0050] Preparation Example 3

[0051] This preparation example provides a food-medicine homologous composition with the effects of regulating immunity, relieving fatigue, and soothing the throat. By weight, the raw materials are 100 parts of Phyllanthus emblica, 70 parts of Astragalus membranaceus, 30 parts of Lycium barbarum, 10 parts of Platycodon grandiflorus, and 10 parts of Mentha haplocalyx. The preparation method is as follows:

[0052] Step (1): Weigh out the following ingredients by weight: Phyllanthus emblica, Astragalus membranaceus, Platycodon grandiflorus, and Mentha haplocalyx. Crush them into coarse powder. Add 90wt% ethanol aqueous solution at a ratio of 8L / 1Kg of coarse powder. Sonicate at 30kHz and heat at 50℃ for 4 hours. Filter and concentrate to 1 / 8 of the original volume to obtain mixture A.

[0053] Step (2): Weigh the wolfberries according to the weight, add water at a rate of 6L / 1Kg of wolfberries, sonicate at 30kHz and heat at 50℃ for 4 hours, filter, and concentrate to 1 / 6 of the original volume to obtain mixture B;

[0054] Step (3): Mix mixture A and mixture B to obtain the medicinal and edible homologous composition.

[0055] Preparation Example 4

[0056] This preparation example provides a food-medicine composition with the effects of regulating immunity, relieving fatigue, and soothing the throat. The only difference between this composition and Preparation Example 2 is that the raw materials also include 16 parts of dried tangerine peel, and in step (1), the ingredients of Phyllanthus emblica, Astragalus membranaceus, Platycodon grandiflorus, Mentha haplocalyx, and dried tangerine peel are weighed by weight and then crushed into coarse powder. Everything else is the same as in Preparation Example 2.

[0057] Preparation Example 5

[0058] This preparation example provides a medicinal and edible composition with the effects of regulating immunity, relieving fatigue, and soothing the throat. The only difference between this composition and Preparation Example 2 is that the raw materials also include 16 parts of licorice, and in step (1), Phyllanthus emblica, Astragalus membranaceus, Platycodon grandiflorus, Mentha haplocalyx, and licorice are weighed by weight and then crushed into coarse powder. Everything else is the same as Preparation Example 2.

[0059] Preparation Example 6

[0060] This preparation example provides a food-medicine composition with the effects of regulating immunity, relieving fatigue, and soothing the throat. The only difference between this composition and Preparation Example 2 is that the raw materials also include 8 parts of dried tangerine peel and 8 parts of licorice, and in step (1), the ingredients of Phyllanthus emblica, Astragalus membranaceus, Platycodon grandiflorus, Mentha haplocalyx, dried tangerine peel, and licorice are weighed by weight and then crushed into coarse powder. Everything else is the same as Preparation Example 2.

[0061] Comparative Preparation Example 1

[0062] This comparative preparation example provides a medicinal and edible homologous composition, the raw materials of which, by weight, are 100 parts of Phyllanthus emblica, 50 parts of Astragalus membranaceus, 50 parts of Lycium barbarum, 10 parts of Platycodon grandiflorus, and 10 parts of Mentha haplocalyx; the preparation method is as follows:

[0063] Weigh out the following ingredients by weight: Phyllanthus emblica, Astragalus membranaceus, Lycium barbarum, Platycodon grandiflorus, and Mentha haplocalyx. Crush them into coarse powder. Add 70wt% ethanol aqueous solution at a ratio of 10L / 1Kg of coarse powder. Sonicate at 30kHz and heat at 60℃ for 2 hours. Filter and concentrate to 1 / 10 of the original volume to obtain the medicinal and edible homologous composition.

[0064] Comparative Preparation Example 2

[0065] This comparative preparation example provides a medicinal and edible composition, which differs from Preparation Example 2 only in that: the raw materials are 100 parts of Phyllanthus emblica, 100 parts of Astragalus membranaceus, 10 parts of Platycodon grandiflorus, and 10 parts of Mentha haplocalyx, and the corresponding preparation method does not include steps (2) and (3). Everything else is the same as Preparation Example 2.

[0066] Comparative preparation example 3

[0067] This comparative preparation example provides a medicinal and edible composition, which differs from Preparation Example 2 only in that: the raw materials are 100 parts of Phyllanthus emblica, 100 parts of Lycium barbarum, 10 parts of Platycodon grandiflorus, and 10 parts of Mentha haplocalyx, and in step (1), Phyllanthus emblica, Platycodon grandiflorus, and Mentha haplocalyx are weighed according to their weight parts and then crushed into coarse powder. Everything else is the same as Preparation Example 2.

[0068] Example 1

[0069] This embodiment provides a medicinal and edible herbal composition: Take an appropriate amount of the medicinal and edible composition of Preparation Example 1, add 50°C warm water at a ratio of 1g of raw material to 2mL of water, stir evenly, and cool to obtain medicinal and edible herbal composition A.

[0070] Examples 2-3 and Comparative Examples 1-3

[0071] This embodiment and the comparative example provide a medicinal and edible herbal composition, which differs from Example 1 only in that: appropriate amounts of the medicinal and edible compositions of Preparation Examples 2-3 and Comparative Preparation Examples 1-3 are taken respectively, and medicinal and edible herbal compositions B, C, D, E and F are obtained respectively.

[0072] Performance testing

[0073] 1. Sensory testing

[0074] Take 5g of each of the food-medicine homology compositions from Preparation Examples 1-6 and Comparative Preparation Examples 1-3, and add 45mL of water to prepare food-medicine homology beverages A, B, C, D, E, F, G, H, and I. Twenty individuals aged 21-60 years who had experienced dry throat for the past week were randomly selected as a judging panel, with half male and half female, and half aged 21-40 and half aged 41-60. Each judge tasted the above food-medicine homology beverages A-I and evaluated them from the perspectives of initial astringency, throat moisturizing sensation, overall taste, and overall aroma.

[0075] For the initial astringency upon entry, a score of 1 to 5 represents very strong, strong, average, slight, and none, respectively.

[0076] For the sensation of moisture in the throat, a score of 1 to 5 represents none, slight, moderate, strong, and very strong, respectively.

[0077] For overall taste and aroma, 1 to 5 points represent very poor, poor, average, good, and very good, respectively.

[0078] The number of people corresponding to different sensory performances was counted, and their average scores were calculated. The results are shown in Table 1. The higher the score, the better the sensory quality.

[0079] Table 1

[0080]

[0081] 2. Efficacy Research

[0082] 2.1 Kunming mouse model of chronic pharyngitis and lymphocyte proliferation assay

[0083] Healthy male Kunming mice weighing 28-30g were selected and acclimatized for 7 days. The mouse model was established as follows: 10% ammonia solution was placed in a sprayer and sprayed into the pharynx of each mouse twice, three times a day at 8-hour intervals, for 21 days. The mice were observed for general condition. Successful model establishment was indicated by the following: rough, dull fur; increased oral secretions and water intake; head-rubbing against bedding; scratching of the lips; and, upon examination with a reflective microscope, congestion and swelling of the pharynx with abundant secretions.

[0084] Subsequently, the mice that had successfully developed the model were randomly divided into 8 groups of 6 mice each, and the mice in each group were treated as follows:

[0085] Negative control group: administered 12 mL / kg of normal saline by gavage;

[0086] Positive control group: administered 12 mL / kg of throat-soothing oral solution by gavage;

[0087] Examples 1-3 and Comparative Examples 1-3: The above-mentioned medicinal and edible herbal compositions A-F were administered by gavage at a dose of 12 mL / kg (equivalent to 6 g of raw material / kg mouse).

[0088] Another group of non-modeled Kunming mice that had undergone adaptive feeding were used as a control group and were administered 12 mL / kg of physiological saline by gavage.

[0089] The above treatment was administered once a day for 21 consecutive days.

[0090] 24 hours after completing the above treatment, the mice were observed and scored according to the following method:

[0091] The mouse's pharyngeal surface is moist and shiny, without pathological symptoms such as congestion or swelling, and is light red in color with no secretions attached; it is scored as 0 points.

[0092] The mouse's pharyngeal surface was not shiny, with a small amount of acute congestion and a small amount of secretions attached, scoring 1 point;

[0093] The mouse's pharyngeal surface was poorly colored and dark red, with pathological phenomena such as acute and mild swelling, and secretions were attached, scoring 2 points;

[0094] The mouse's pharynx was dark red and dark in color, with obvious pathological phenomena such as acute congestion and swelling, and a large amount of secretions attached, scoring 3 points.

[0095] The average score of each group of mice was calculated, and the results are shown in Table 2. The lower the score, the better the throat-soothing effect.

[0096] After the above observations were completed, mice in the blank group, Examples 1-3, and Comparative Examples 1-3 were euthanized by cervical dislocation. The ConA-induced mouse spleen lymphocyte transformation experiment was performed according to the "Evaluation Procedures and Testing Methods for Functional Evaluation of Health Foods," specifically the testing method for enhancing immune function. The MTT assay was used to determine lymphocyte proliferation capacity, and the results are shown in Table 2. The optical density (OD) at 570 nm was measured using a semi-automatic biochemical analyzer. Lymphocyte proliferation capacity = OD with ConA pores - OD without ConA pores; a higher value indicates stronger immunity.

[0097] 2.2 Kunming Mouse Weight-Bearing Swimming Test

[0098] Healthy male Kunming mice weighing 28-30g were selected and acclimatized for 7 days. They were then randomly divided into 7 groups of 6 mice each, and each group underwent the following treatments:

[0099] Control group: Administered 12 mL / kg of normal saline by gavage;

[0100] Examples 1-3 and Comparative Examples 1-3: The above-mentioned medicinal and edible herbal compositions A-F were administered by gavage at a dose of 12 mL / Kg (equivalent to 6g of raw material / Kg of mouse).

[0101] The above treatment was performed once a day for three consecutive days; and, except during the gavage, the patient was kept in a low-pressure environment of 700 hPa at all other times.

[0102] Thirty minutes after the above treatment, each group of mice was placed in a swimming tank (water depth 30cm, water temperature 25℃) with 5% of their body weight of lead attached to their tails. The time from the start of swimming to exhaustion (when the mouse’s head was completely submerged in the water for 10 seconds and could not float to the surface) was recorded. The results are shown in Table 2.

[0103] Table 2

[0104]

[0105] As shown in Table 1, the medicinal and edible homologous beverages prepared from the medicinal and edible homologous compositions obtained in Examples 1-6 of this invention have a relatively weak initial astringent taste and a strong throat-moistening sensation, as well as good overall taste and aroma, indicating good sensory quality. As shown in Table 2, the medicinal and edible homologous traditional Chinese medicine compositions obtained in Examples 1-3 of this invention have the effects of soothing the throat, enhancing immunity, and relieving fatigue. Therefore, the medicinal and edible homologous traditional Chinese medicine compositions of this invention can be used as daily beverages that simultaneously possess both good taste and health benefits.

[0106] In contrast, Comparative Example 1, which used ultrasonic heating of all raw materials with ethanol aqueous solution, had a worse effect on enhancing immunity and relieving fatigue than Examples 1-3 of the present invention. Comparative Examples 2-3, which did not use the combination of Astragalus membranaceus and Lycium barbarum in the "Qi and Yin tonification" pattern, also had a worse effect on soothing the throat and enhancing immunity than Examples 1-3 of the present invention. In terms of health care functions, none of them could have a good multiple effects.

[0107] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and not to limit it. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that after reading this application specification, they can still modify or make equivalent substitutions to the specific implementation of the present invention, but these modifications or changes do not depart from the protection scope of the pending claims of the present invention.

Claims

1. A medicinal and edible homologous traditional Chinese medicine composition with the effects of regulating immunity, relieving fatigue and benefiting the throat, characterized in that, The preparation raw materials include, by weight parts: Phyllanthus emblica 100 parts, Astragalus 30-70 parts, Fructus Lycii 30-70 parts, Platycodon 1-20 parts, and Mentha 1-20 parts; The preparation method comprises the following steps: Phyllanthus emblica, Astragalus, Platycodon, and Mentha are weighed by weight parts, crushed into coarse powder, added with an ethanol aqueous solution with a concentration of 50 wt% or above, ultrasonically treated and heated, filtered, and a mixture A is obtained; Fructus Lycii is weighed by weight parts, added with water, ultrasonically treated, filtered, and a mixture B is obtained; The mixture A and the mixture B are mixed, and the medicine-food homologous traditional Chinese medicine composition with the effects of regulating immunity, relieving fatigue, and relieving sore throat and moistening throat is obtained.

2. The medicinal and edible traditional Chinese medicine composition according to claim 1, characterized in that, The preparation raw materials further include 1-20 parts of Pericarpium Citri Reticulatae. 3.The medicinal and edible traditional Chinese medicine composition of claim 1, characterized in that, The preparation raw materials further include 1-20 parts of Glycyrrhiza.

4. The method for preparing the medicinal and edible herbal composition according to any one of claims 1 to 3, characterized in that, The preparation method comprises the following steps: S1. Phyllanthus emblica, Astragalus, Platycodon, and Mentha, and optionally Pericarpium Citri Reticulatae and optionally Glycyrrhiza are weighed by weight parts, crushed into coarse powder, added with an ethanol aqueous solution with a concentration of 50 wt% or above, ultrasonically treated and heated, filtered, and a mixture A is obtained; S2. Fructus Lycii is weighed by weight parts, added with water, ultrasonically treated, filtered, and a mixture B is obtained; S3. The mixture A and the mixture B are mixed, and the medicine-food homologous traditional Chinese medicine composition is obtained.

5. The preparation method according to claim 4, characterized in that, In S1 and / or S2, after the filtering step, a concentrating step is further included.

6. The preparation method according to claim 4, characterized in that, In S1, the concentration of the ethanol aqueous solution is 50 wt%-90 wt%; And / or, the use amount ratio of the ethanol aqueous solution to the coarse powder is 3-20 L:1 Kg; And / or, the frequency of the ultrasonic treatment is 15-40 kHz; And / or, the heating temperature is 50-85 ℃; And / or, the treatment time is 30 minutes-6 hours.

7. The preparation method according to claim 4, characterized in that, In S2, the use amount ratio of the water to the Fructus Lycii is 3-15 L:1 Kg; And / or, the frequency of the ultrasonic treatment is 15-40 kHz; And / or, the ultrasonic treatment process further includes a heating step; And / or, the ultrasonic treatment time is 20 minutes-5 hours.

8. The production method according to claim 7, characterized by, The heating temperature in the ultrasonic treatment process is 35-100 ℃.

9. A preparation having the effects of regulating immunity, relieving fatigue and benefiting the throat, characterized by comprising the following components in the preparation: The medicine-food homologous traditional Chinese medicine composition according to any one of claims 1-3, and a pharmaceutically acceptable excipient or a food acceptable excipient. ​ 10. The preparation according to claim 9, characterized in that The dosage form of the preparation includes granules or liquid dosage forms; And / or, the preparation is a liquid beverage or a solid beverage.

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