Traditional Chinese medicine composition for treating rheumatoid arthritis and gout and preparation method thereof
By decocting and extracting a combination of traditional Chinese medicines such as lotus seed heart, the treatment challenges of rheumatoid arthritis and gout have been solved, achieving significant therapeutic effects, reducing serum uric acid, alleviating joint symptoms, and improving patients' quality of life.
Patent Information
- Application Number
- CN202511940073.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-12-22
- Publication Date
- 2026-01-30
AI Technical Summary
Existing technologies are insufficient to effectively treat rheumatoid arthritis and gout, and the development of traditional Chinese medicine drugs is inadequate.
A combination of traditional Chinese medicines, including lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, and honeysuckle, is used to treat rheumatoid arthritis and gout by decoction and separation. The treatment utilizes the methods of clearing turbidity and unblocking collaterals, clearing heat and detoxifying, and dispelling wind and dampness.
It significantly improves the symptoms of rheumatoid arthritis and gout, lowers serum uric acid, promotes uric acid excretion, reduces joint swelling and pain, and improves patients' joint mobility.
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Abstract
Description
Technical Field
[0001] This invention relates to the field of traditional Chinese medicine technology, and in particular to a traditional Chinese medicine composition for treating rheumatoid arthritis and gout, and its preparation method. Background Technology
[0002] Rheumatoid arthritis and gout are common clinical conditions that cause significant physical suffering for patients. Therefore, effective treatment of these two diseases is of great importance.
[0003] Rheumatoid arthritis is a chronic rheumatic systemic disease characterized by inflammatory synovitis. Its pathogenesis is related to immune factors, mainly due to the immune system attacking its own tissues and organs, leading to inflammation. However, the specific cause is still unclear.
[0004] Gout, a metabolic disease, is primarily caused by chronically elevated blood uric acid levels. In gout patients, uric acid production exceeds the kidneys' excretion capacity, leading to a sustained increase in blood uric acid concentration. When uric acid exceeds saturation, crystals form and deposit in joints and tissues, triggering an inflammatory response.
[0005] In Western medicine, treatment for these diseases is tailored to their different manifestations and causes. For example, colchicine is commonly used to treat gout, while nonsteroidal anti-inflammatory drugs (NSAIDs) and biologics are mainly used for rheumatoid arthritis.
[0006] From the perspective of traditional Chinese medicine, both gout and rheumatoid arthritis can manifest as joint pain, swelling, and difficulty in flexion and extension, which conforms to the basic characteristics of "Bi syndrome." Therefore, both can be collectively referred to as Bi syndrome. The development of traditional Chinese medicine drugs targeting rheumatoid arthritis and gout is a problem faced by those skilled in the art. Summary of the Invention
[0007] In view of this, the present invention provides a traditional Chinese medicine composition for treating rheumatoid arthritis and gout and a method for preparing the same. The traditional Chinese medicine composition for treating rheumatoid arthritis and gout provided by the present invention can be used for rheumatoid arthritis and gout with significant effects.
[0008] This invention provides a traditional Chinese medicine composition for treating rheumatoid arthritis and gout, comprising the following components in parts by weight: Lotus seed heart 20-34 parts, coix seed 15-22 parts, plantain seed 3-10 parts, salvia miltiorrhiza 2-7 parts, dried ginger 25-30 parts, achyranthes bidentata 8-11 parts, alisma plantago-aquatica 10-17 parts, chicken blood vine 3-9 parts, notoginseng 1-4 parts, and honeysuckle 16-28 parts.
[0009] Preferably, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout comprises 20-34 parts of lotus seed heart, more preferably 24-30 parts, and even more preferably 28 parts, by weight.
[0010] Preferably, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout includes 15-22 parts of coix seed, more preferably 17-20 parts, and even more preferably 19 parts, by weight.
[0011] Preferably, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout comprises 3 to 10 parts of Plantago asiatica, more preferably 5 to 8 parts, and even more preferably 6.5 parts, by weight.
[0012] Preferably, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout includes 2 to 7 parts of Salvia miltiorrhiza, more preferably 3 to 6 parts, and even more preferably 5.5 parts, by weight.
[0013] Preferably, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout comprises 25-30 parts of dried ginger, more preferably 26-29 parts, and even more preferably 27 parts, by weight.
[0014] Preferably, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout includes 8-11 parts of Achyranthes bidentata, more preferably 9-10 parts, and even more preferably 9.3 parts, by weight.
[0015] Preferably, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout includes 10-17 parts of Alisma plantago-aquatica, more preferably 13-16 parts, and even more preferably 15.2 parts, by weight.
[0016] Preferably, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout comprises 3 to 9 parts of chicken blood vine, more preferably 5 to 8 parts, and even more preferably 7 parts, by weight.
[0017] Preferably, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout comprises 1 to 4 parts of Panax notoginseng, more preferably 2 to 3 parts, and even more preferably 3 parts, by weight.
[0018] Preferably, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout includes 16-28 parts of honeysuckle, more preferably 18-25 parts, and even more preferably 22.4 parts, by weight.
[0019] This invention also provides a method for preparing the traditional Chinese medicine composition for treating rheumatoid arthritis and gout as described above, comprising the following steps: The lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 7-8 times the amount of water are mixed and decocted for 45-55 minutes. The solid and liquid are separated to obtain the Chinese herbal composition for treating rheumatoid arthritis and gout.
[0020] Preferably, the decoction is performed 1 to 2 times. When the decoction is performed 2 times, the amount of water used for the second decoction is 3 to 4 times the amount of water used.
[0021] Preferably, when the decocting is performed twice, the process includes filtration after the first decocting.
[0022] Preferably, the solid-liquid separation is filtration.
[0023] The present invention has achieved the following beneficial effects: This invention provides a traditional Chinese medicine composition for treating rheumatoid arthritis and gout, formulated as described above, which exhibits significant effects on both conditions. The traditional Chinese medicine composition for treating rheumatoid arthritis and gout provided by this invention, through the synergistic effect of the aforementioned components and by controlling the content of each component, effectively exerts the efficacy of each component, reduces antagonistic effects between components, and significantly improves the overall efficacy of the traditional Chinese medicine composition. The traditional Chinese medicine composition for treating rheumatoid arthritis and gout provided by this invention acts on the lesions of rheumatoid arthritis and gout through at least three pathways: clearing turbidity and unblocking the meridians, clearing heat and detoxifying, and dispelling wind and dampness, resulting in ideal and stable overall effects. Detailed Implementation
[0025] Example 1 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 20g lotus seed heart, 22g coix seed, 10g plantain seed, 2g salvia miltiorrhiza, 25g dried ginger, 8g achyranthes bidentata, 10g alisma plantago-aquatica, 9g chicken blood vine, 1g notoginseng, and 28g honeysuckle.
[0026] The ingredients, including lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle, and 7 times the amount of water, were decocted for 45 minutes. The dregs were then filtered out to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0027] Example 2 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 34g of lotus seed heart, 22g of coix seed, 10g of plantain seed, 7g of salvia miltiorrhiza, 25g of dried ginger, 8g of achyranthes bidentata, 17g of alisma plantago-aquatica, 3g of chicken blood vine, 1g of notoginseng, and 16g of honeysuckle.
[0028] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 8 times the amount of water and decoct for 45 minutes. Filter out the dregs to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0029] Example 3 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 20g lotus seed heart, 15g coix seed, 3g plantain seed, 7g salvia miltiorrhiza, 30g dried ginger, 11g achyranthes bidentata, 17g alisma plantago-aquatica, 9g chicken blood vine, 4g notoginseng, and 16g honeysuckle.
[0030] The ingredients, including lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle, and 7 times the amount of water, were mixed and decocted for 48 minutes. The dregs were then filtered out to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0031] Example 4 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 24g of lotus seed heart, 17g of coix seed, 8g of plantain seed, 6g of salvia miltiorrhiza, 29g of dried ginger, 9g of achyranthes bidentata, 13g of alisma plantago-aquatica, 8g of chicken blood vine, 2g of notoginseng, and 25g of honeysuckle.
[0032] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 7 times the amount of water and decoct for 55 minutes. Filter out the dregs to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0033] Example 5 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 30g of lotus seed heart, 20g of coix seed, 5g of plantain seed, 3g of salvia miltiorrhiza, 26g of dried ginger, 9g of achyranthes bidentata, 13g of alisma plantago-aquatica, 8g of chicken blood vine, 3g of notoginseng, and 18g of honeysuckle.
[0034] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 8 times the amount of water and decoct for 50 minutes. Filter out the dregs to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0035] Example 6 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 30g of lotus seed heart, 20g of coix seed, 8g of plantain seed, 6g of salvia miltiorrhiza, 29g of dried ginger, 10g of achyranthes bidentata, 16g of alisma plantago-aquatica, 8g of chicken blood vine, 3g of notoginseng, and 25g of honeysuckle.
[0036] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 7 times the amount of water and decoct for 55 minutes. Filter out the dregs to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0037] Example 7 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 24g lotus seed heart, 17g coix seed, 5g plantain seed, 3g salvia miltiorrhiza, 29g dried ginger, 9g achyranthes bidentata, 16g alisma plantago-aquatica, 8g chicken blood vine, 3g notoginseng, and 25g honeysuckle.
[0038] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 7 times the amount of water and decoct for 55 minutes. Filter out the dregs to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0039] Example 8 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 30g of lotus seed heart, 17g of coix seed, 5g of plantain seed, 6g of salvia miltiorrhiza, 29g of dried ginger, 10g of achyranthes bidentata, 13g of alisma plantago-aquatica, 8g of chicken blood vine, 3g of notoginseng, and 18g of honeysuckle.
[0040] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 8 times the amount of water and decoct for 55 minutes. Filter out the dregs to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0041] Example 9 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 28g of lotus seed heart, 19g of coix seed, 6.5g of plantain seed, 5.5g of salvia miltiorrhiza, 27g of dried ginger, 9.3g of achyranthes bidentata, 15.2g of alisma plantago-aquatica, 7g of chicken blood vine, 3g of notoginseng, and 22.4g of honeysuckle.
[0042] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 8 times the amount of water and decoct for 52 minutes. Filter out the dregs to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0043] Example 10 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 22g of lotus seed heart, 18g of coix seed, 6.5g of plantain seed, 5g of salvia miltiorrhiza, 27g of dried ginger, 10g of achyranthes bidentata, 11g of alisma plantago-aquatica, 4g of chicken blood vine, 4g of notoginseng, and 28g of honeysuckle.
[0044] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 7 times the amount of water and decoct for 55 minutes. Filter out the dregs to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0045] Example 11 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 23g lotus seed heart, 21g coix seed, 7g plantain seed, 5.5g salvia miltiorrhiza, 28g dried ginger, 9.5g achyranthes bidentata, 11g alisma plantago-aquatica, 6g chicken blood vine, 3g notoginseng, and 21g honeysuckle.
[0046] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 8 times the amount of water and decoct for 55 minutes. Filter out the dregs to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0047] Example 12 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 33g of lotus seed heart, 21g of coix seed, 9g of plantain seed, 4g of salvia miltiorrhiza, 27g of dried ginger, 9g of achyranthes bidentata, 14g of alisma plantago-aquatica, 4g of chicken blood vine, 1g of notoginseng, and 20g of honeysuckle.
[0048] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 7 times the amount of water and decoct for 54 minutes. Filter out the dregs to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0049] Example 13 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 33g of lotus seed heart, 21g of coix seed, 9g of plantain seed, 4g of salvia miltiorrhiza, 27g of dried ginger, 9g of achyranthes bidentata, 14g of alisma plantago-aquatica, 4g of chicken blood vine, 1g of notoginseng, and 20g of honeysuckle.
[0050] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 7 times the amount of water and decoct for 54 minutes. Filter to obtain the first decoction and dregs. Mix the dregs with 4 times the amount of water and decoct for 55 minutes. Filter to obtain the second decoction. Combine the first and second decoctions to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0051] Example 14 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 33g of lotus seed heart, 21g of coix seed, 9g of plantain seed, 4g of salvia miltiorrhiza, 27g of dried ginger, 9g of achyranthes bidentata, 14g of alisma plantago-aquatica, 4g of chicken blood vine, 1g of notoginseng, and 20g of honeysuckle.
[0052] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 7 times the amount of water and decoct for 54 minutes. Filter to obtain the first decoction and dregs. Mix the dregs with 3 times the amount of water and decoct for 45 minutes. Filter to obtain the second decoction. Combine the first and second decoctions to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0053] Example 15 This embodiment prepares a traditional Chinese medicine composition for treating rheumatoid arthritis and gout. The components are: 33g of lotus seed heart, 21g of coix seed, 9g of plantain seed, 4g of salvia miltiorrhiza, 27g of dried ginger, 9g of achyranthes bidentata, 14g of alisma plantago-aquatica, 4g of chicken blood vine, 1g of notoginseng, and 20g of honeysuckle.
[0054] Mix lotus seed heart, coix seed, plantain seed, salvia miltiorrhiza, dried ginger, achyranthes bidentata, alisma plantago-aquatica, chicken blood vine, notoginseng, honeysuckle and 7 times the amount of water and decoct for 54 minutes. Filter to obtain the first decoction and dregs. Mix the dregs with 3 times the amount of water and decoct for 45 minutes. Filter to obtain the second decoction. Combine the first and second decoctions to obtain a traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
[0055] Comparative Example 1 The preparation method of this comparative example is the same as that of Example 9, except that lotus seed hearts were not added.
[0056] Comparative Example 2 The preparation method of this comparative example is the same as that of Example 9, except that the amount of lotus seed heart is replaced with 37 grams.
[0057] Comparative Example 3 The preparation method of this comparative example is the same as that of Example 9, except that no psyllium husk was added.
[0058] Comparative Example 4 The preparation method of this comparative example is the same as that of Example 9, except that the amount of Plantago seed is replaced with 13 grams.
[0059] Comparative Example 5 The preparation method of this comparative example is the same as that of Example 9, except that Alisma plantago-aquatica was not added.
[0060] Comparative Example 6 The preparation method of this comparative example is the same as that of Example 9, except that the amount of Alisma plantago-aquatica is replaced with 20 grams.
[0061] Comparative Example 7 The preparation method of this comparative example is the same as that of Example 9, except that no chicken blood vine or Panax notoginseng were added.
[0062] Test Example 1 The efficacy of the traditional Chinese medicine compositions for treating rheumatoid arthritis and gout prepared in Examples 1-15 and Comparative Examples 1-7 of this invention was tested. The testing method was as follows: 125 SPF-grade SD rats with a weight distribution in the range of 180-200 grams were selected. The rats were randomly divided into 25 groups, including 15 example groups (administered with the traditional Chinese medicine composition solution of Examples 1-15 by gavage), 7 comparative example groups (administered with the traditional Chinese medicine composition solution of Comparative Examples 1-7 by gavage), a blank control group (no modeling, no medication, administered with an equal volume of drinking water by gavage), a model control group (no medication, administered with an equal volume of drinking water by gavage), and a positive control group (colchicine, administered to each rat by gavage at a dose of 0.5 mg / kg per day).
[0063] Rats in the example group, comparative group, model control group, and positive control group were subjected to modeling. The modeling drug was a suspension of potassium oxonate (400 mg / kg) and adenine (0.1 g / kg) (solvent was 0.1% CMC-Na). The modeling drug was administered by gavage at a dose of 10 mL / kg in the morning and 5 mL / kg in the afternoon. The blank control group and the model control group were administered the same volume of drinking water by gavage. The modeling and drug administration were carried out continuously for 30 days. The serum uric acid and urine uric acid of the rats were measured. The results are shown in Table 1.
[0064] Table 1. Serum and urinary uric acid levels in rats of Test Example 1.
[0065] As shown in Table 1, the serum uric acid level in the model control group was significantly higher than that in the blank control group, proving the successful establishment of the model in this test case. The serum uric acid level in the rats of the embodiment group of this invention was significantly lower, while the comparative group showed a slight decrease. Overall, the serum uric acid level in the rats of the embodiment group of this invention was higher than that in the positive control group. This may be because the test period only covered one course of treatment with the traditional Chinese medicine composition of this invention, and the effect of the composition was not fully realized. The above results indicate that the traditional Chinese medicine composition for treating rheumatoid arthritis and gout provided by this invention can effectively reduce serum uric acid, promote uric acid excretion, and alleviate gout symptoms.
[0066] Test Example 2 This study recruited 120 patients with rheumatoid arthritis. These patients had no other comorbidities, were aged 25-45 years, and included 68 males and 52 females. They were randomly divided into 24 groups: 15 example groups (receiving 500 ml of the herbal composition solution from Examples 1-15, twice daily, morning and evening); 7 comparative groups (receiving 500 ml of the herbal composition solution from Examples 1-7, twice daily, morning and evening); a blank control group (receiving no medication, but an equal volume of saline); and a positive control group (receiving 100 mg of diclofenac daily, divided into two doses). Patients took the corresponding medication at 11:00 AM and 5:00 PM before meals daily. The blank control group received an equal volume of saline. The study lasted for 90 days, and the results are shown in Table 2.
[0067] Table 2 Results of Test Case 2: Patients with Rheumatoid Arthritis
[0068] Note: Average morning stiffness time refers to the average morning stiffness time of the patients in this group, accurate to 1 minute; Average joint swelling degree refers to the average joint swelling degree of the patients in this group, where grade 0 indicates no joint swelling, grade 1 indicates slight joint bulging, clear bony landmarks, and no pitting edema, grade 2 indicates significant bulging of the surrounding tissues, blurred bony landmarks, and possible mild pitting edema, and grade 3 indicates significant joint bulging, complete disappearance of bony landmarks, and significant pitting edema; Average joint mobility refers to the average joint mobility of the patients in this group, where grade 0 indicates no pain, grade 1 indicates tolerable pain during activity that does not affect activity, grade 2 indicates significant pain during activity and limited activity, and grade 3 indicates severe pain during activity and inability to complete the target activity; if the relevant indicators of average joint swelling degree and average joint mobility fall between any two grades, a grade of 0.5 can be taken.
[0069] As shown in Table 2, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout provided by this invention can reach the level of the positive control group. Compared with the blank control group, the morning stiffness time, joint swelling degree and joint mobility of the embodiment group of this invention are significantly improved. Compared with the comparative group, the various indicators of the embodiment group of this invention are also significantly improved, proving that the traditional Chinese medicine composition for treating rheumatoid arthritis and gout provided by this invention can effectively improve rheumatoid arthritis through the synergistic effect of the components in specific amounts, and the patients' clinical experience is significantly improved.
[0070] In summary, the traditional Chinese medicine composition for treating rheumatoid arthritis and gout provided by this invention can improve the condition of rheumatoid arthritis and gout, with good overall effects.
[0071] The embodiments of the present invention have been described above; however, these embodiments are merely illustrative and not intended to limit the scope of the invention. Although various embodiments have been described above, this does not mean that the measures in the embodiments cannot be used advantageously in combination. Various substitutions and modifications can be made by those skilled in the art without departing from the scope of the invention, and all such substitutions and modifications should fall within the scope of the invention.
Claims
1. A traditional Chinese medicine composition for treating rheumatoid arthritis and gout, characterized in that, The components include the following quality parts: Plumula Nelumbinis 20-34 parts, Coicis Semen 15-22 parts, Plantaginis Semen 3-10 parts, Salvia miltiorrhiza 2-7 parts, Zingiber officinale 25-30 parts, Cyathula 8-11 parts, Alisma orientalis 10-17 parts, Spatholobus suberectus 3-9 parts, Panax notoginseng 1-4 parts and Lonicera japonica 16-28 parts.
2. The Chinese medicine composition for treating rheumatoid arthritis and gout according to claim 1, characterized in that, According to quality parts, it includes Plumula Nelumbinis 24-30 parts, Coicis Semen 17-20 parts, Plantaginis Semen 5-8 parts, Salvia miltiorrhiza 3-6 parts, Zingiber officinale 26-29 parts, Cyathula 9-10 parts, Alisma orientalis 13-16 parts, Spatholobus suberectus 5-8 parts, Panax notoginseng 2-3 parts and Lonicera japonica 18-25 parts.
3. The traditional Chinese medicine composition for treating rheumatoid arthritis and gout according to claim 1 or 2, characterized in that, According to quality parts, it includes Plumula Nelumbinis 28 parts, Coicis Semen 19 parts, Plantaginis Semen 6.5 parts, Salvia miltiorrhiza 5.5 parts, Zingiber officinale 27 parts, Cyathula 9.3 parts, Alisma orientalis 15.2 parts, Spatholobus suberectus 7 parts, Panax notoginseng 3 parts and Lonicera japonica 22.4 parts.
4. The Chinese medicine composition for treating rheumatoid arthritis and gout according to claim 1, characterized in that, According to quality parts, it includes Plumula Nelumbinis 30 parts, Coicis Semen 20 parts, Plantaginis Semen 8 parts, Salvia miltiorrhiza 6 parts, Zingiber officinale 29 parts, Cyathula 10 parts, Alisma orientalis 16 parts, Spatholobus suberectus 8 parts, Panax notoginseng 3 parts and Lonicera japonica 25 parts.
5. The Chinese medicine composition for treating rheumatoid arthritis and gout according to claim 1 or 2, characterized in that, According to quality parts, it includes Plumula Nelumbinis 24 parts, Coicis Semen 17 parts, Plantaginis Semen 5 parts, Salvia miltiorrhiza 3 parts, Zingiber officinale 29 parts, Cyathula 9 parts, Alisma orientalis 16 parts, Spatholobus suberectus 8 parts, Panax notoginseng 3 parts and Lonicera japonica 25 parts.
6. The method for preparing the traditional Chinese medicine composition for treating rheumatoid arthritis and gout according to any one of claims 1-5, characterized in that, The steps include the following: Plumula Nelumbinis, Coicis Semen, Plantaginis Semen, Salvia miltiorrhiza, Zingiber officinale, Cyathula, Alisma orientalis, Spatholobus suberectus, Panax notoginseng, Lonicera japonica and 7-8 times amount of water are mixed and decocted for 45-55 minutes, and then solid-liquid separation is performed to obtain the traditional Chinese medicine composition for treating rheumatoid arthritis and gout.
7. The production method according to claim 6, wherein The decocting times are 1-2 times.
8. The production method according to claim 7, characterized by, When the decocting times are 2 times, the amount of water used in the second decocting is 3-4 times.
9. The preparation method according to claim 7, characterized in that, When the decocting times are 2 times, the first decocting further includes filtering.
10. The method of claim 6, wherein, The solid-liquid separation is filtering.
