Efficient crystallization equipment for p-hydroxyacetophenone

Abstract

The invention discloses efficient crystallization equipment for p-hydroxyacetophenone, and belongs to the technical field of p-hydroxyacetophenone production, and the efficient crystallization equipment is technically characterized by comprising a supporting table, the equipment can flexibly switch medicament forms according to process parameters such as feed liquid concentration, temperature and stirring rate, when feed liquid is in a high-viscosity state, liquid medicaments are easier to uniformly mix, and the crystallization efficiency is improved. When a crystallization system needs to be stabilized for a long time, the solid medicament can prolong the action period, reduce the supplementing frequency, adapt to intermittent and continuous production processes, is small in dosage and high in stability, does not need to be additionally provided with a dissolving device, and reduces energy consumption; according to the present invention, the automatic control is achieved, the manual operation error is reduced, the continuous production process is formed through the arranged crystallization treatment mechanism, the previous process creates the high-quality condition for the subsequent process, and the advantages of easy agent selective addition and good crystallization effect are provided.

Description

Technical Field

[0001] This invention relates to the field of p-hydroxyacetophenone production, and more specifically to a high-efficiency crystallization device for p-hydroxyacetophenone. Background Technology

[0002] p-Hydroxyacetophenone (p-hydroxyacetophenone), as an important organic synthetic intermediate and fine chemical product, is widely used in pharmaceuticals, cosmetics, and fragrances. In the pharmaceutical field, it is a key raw material for synthesizing antipyretic analgesics and anticardiovascular drugs; its purity directly affects the efficacy and safety of these drugs. In the cosmetics field, it can be used as a stabilizer and preservative; high-purity p-hydroxyacetophenone can effectively prevent deterioration of cosmetics during storage and use, ensuring product quality. Therefore, industrial production requires extremely high purity of p-hydroxyacetophenone, and the crystallization process, as the core step in p-hydroxyacetophenone purification, directly determines the purity, yield, and production efficiency of the product through the performance of its equipment.

[0003] Currently available p-hydroxyacetophenone crystallization equipment generally suffers from low automation. Key parameters such as the amount of antisolvent added during crystal growth are mostly controlled manually, resulting in large parameter fluctuations. This leads to poor consistency in purity and particle size among different batches of products. Furthermore, most equipment cannot add solid or liquid reagents in a timely manner as needed during crystal growth, which significantly reduces subsequent crystallization efficiency and fails to meet actual usage requirements.

[0004] Therefore, there is a need to provide a highly efficient crystallization device for p-hydroxyacetophenone, which aims to solve the above problems. Summary of the Invention

[0005] In view of the shortcomings of the existing technology, the purpose of this invention is to provide a high-efficiency crystallization device for p-hydroxyacetophenone, which aims to solve the technical problems mentioned in the background art.

[0006] To achieve the above objectives, the present invention provides the following technical solution: A high-efficiency crystallization apparatus for p-hydroxyacetophenone includes a support platform, a pretreatment tank for pretreatment is mounted on the support platform, an inlet pipe is connected to the pretreatment tank, a low-temperature vacuum evaporator is connected below the pretreatment tank, and the low-temperature vacuum evaporator is connected to a crystallization tank via a pump body. The apparatus also includes: A solid reagent adding mechanism is installed inside a crystallization chamber to add a quantitative amount of solid reagent into the chamber. The solid reagent adding mechanism includes a first turntable, a second turntable, and a guide pipe for feeding control. The first turntable is fixedly connected to the second turntable via the guide pipe, and both the first and second turntables are rotatably connected to the inside of the crystallization chamber via a second rotating shaft. A sealing plate for sealing is movably installed on one side of the lower end of the guide pipe, and the sealing plate is opened and closed by connection with a slip ring. A liquid agent adding mechanism is installed inside the mounting base and is connected and driven by a solid agent adding mechanism. It is used to add liquid agents quantitatively into the crystallization treatment tank. The liquid agent adding mechanism includes a third turntable for liquid dispensing control and a delivery cylinder. The delivery cylinder is connected to a third liquid guide tube for liquid dispensing. The delivery cylinder performs liquid adding through the forward and reverse rotation of the third turntable. A crystallization processing unit, installed at the connection point on one side of the crystallization processing box, is used for the step-by-step crystallization of p-hydroxyacetophenone.

[0007] As a further embodiment of the present invention, the solid agent adding mechanism further includes a solid agent feeding pipe for solid material feeding docking, a screw feeder is connected to the solid agent feeding pipe, and the solid agent feeding pipe is fixedly installed on the crystallization treatment box, the slip ring is fixedly installed on the fixed pipe by a fixing rod, and the fixed pipe is fixedly installed inside the crystallization treatment box by a mounting seat.

[0008] As a further embodiment of the present invention, the solid agent addition mechanism further includes a docking plate for controlling the material feeding of the sealing plate. The docking plate is fixedly installed on one side of the sealing plate. The docking plate is rotatably connected to the guide pipe via a first rotating shaft. The slip ring is provided with a material feeding guide groove for adapting to the rotational connection of the sealing plate, and the docking plate is adapted to slide on the slip ring and the material feeding guide groove.

[0009] As a further embodiment of the present invention, the solid agent addition mechanism further includes an incomplete gear and a rotating gear for driving the guide tube to rotate and connect. The second rotating shaft is rotatably mounted on a fixed plate, and the fixed plate is fixedly mounted inside the mounting base. One end of the second rotating shaft is fixedly connected to a rotating gear, and an incomplete gear is meshed on the rotating gear. The incomplete gear and the rotating gear have the same diameter, and the number of teeth on the incomplete gear is equal to half the number of teeth on the rotating gear.

[0010] As a further embodiment of the present invention, the solid drug addition mechanism further includes a motor for driving the incomplete gear to rotate. The incomplete gear is rotatably connected to the interior of the mounting base via a third rotating shaft. A worm gear is fixedly connected to the third rotating shaft, and a worm is meshed with the worm gear. The worm is fixedly connected to the output shaft of the motor, and the motor is fixedly installed inside the mounting base.

[0011] As a further embodiment of the present invention, the third rotating shaft is synchronously connected to a stirring shaft via a timing belt, and stirring blades and an anchor-type stirring paddle are fixedly connected to the stirring shaft for mixing.

[0012] As a further embodiment of the present invention, the liquid medicine adding mechanism further includes a rotating guide block and a wedge block for driving the push plate on the infusion cylinder to reciprocate. The rotating guide block is fixedly installed on the non-central side of the third turntable. The third turntable is installed on the third rotating shaft through a one-way bearing. The push plate is provided with a wedge block that is adapted to slide and connected with the rotating guide block. A return spring is provided at the connection between the push plate and the infusion cylinder.

[0013] As a further embodiment of the present invention, the liquid drug addition mechanism further includes a piston plate and a storage tank for driving the infusion cylinder to connect to the liquid supply. The piston plate is fixedly connected to the push plate via a piston rod. The piston plate is slidably connected to the inside of the infusion cylinder, and the infusion cylinder is fixedly installed on the fixed pipe via a connecting plate. A third liquid guide pipe and a fourth liquid guide pipe are fixedly connected to the infusion cylinder. A first one-way valve is provided on the third liquid guide pipe, and a second one-way valve is provided on the fourth liquid guide pipe. One end of the fourth liquid guide pipe is connected to the storage tank, and the storage tank is fixedly installed on the outside of the crystallization processing tank.

[0014] As a further embodiment of the present invention, the crystallization processing mechanism includes a gradient cooling device for docking with the crystallization processing box, a solid-liquid separator is docked on the gradient cooling device, a scrubber is docked on the solid-liquid separator, a vacuum dryer is docked on the scrubber, a sieve is docked on the vacuum dryer, and a discharge pipe for discharging material is provided on the sieve. The sieve is fixedly installed on a support platform.

[0015] As a further embodiment of the present invention, the pretreatment box is equipped with a filter screen and a plate preheater, the low-temperature vacuum evaporator is connected to a pump body through a first liquid guide pipe, the pump body is connected to the interior of the crystallization treatment box through a second liquid guide pipe, and the bottom of the support platform is equipped with support feet for support.

[0016] In summary, the embodiments of the present invention have the following beneficial effects compared with the prior art: This invention allows for selective control of solid and liquid addition through a solid agent addition mechanism and a liquid agent addition mechanism. During the crystallization of p-hydroxyacetophenone, problems such as unstable crystal form, uneven particle size distribution, and difficulty in achieving purity standards are frequently encountered. The solid agent addition (such as specific seed crystals or adsorption-type purification agents) used in this invention can directionally induce the growth of the target crystal form and inhibit impurity crystallization; the liquid agent addition (such as crystallizing agents or dispersants) can quickly disperse in the liquid, adjusting the system viscosity and interfacial tension, and solving the problem of crystal agglomeration caused by excessively slow or fast crystallization rates.

[0017] Meanwhile, this equipment can flexibly switch the form of the reagent according to process parameters such as liquid concentration, temperature, and stirring rate. When the liquid is in a high viscosity state, the liquid reagent is easier to mix evenly, avoiding local concentration imbalance caused by the agglomeration of solid reagent. When a long-term stable crystallization system is required, solid reagent (such as slow-release seed crystals) can extend the action period, reduce the frequency of replenishment, and adapt to intermittent and continuous production processes.

[0018] Solid reagents require less dosage and have high stability, eliminating the need for additional dissolving devices and reducing energy consumption. Liquid reagents can be injected via an infusion cylinder, enabling automated control and reducing human error. Therefore, the equipment in this application integrates a reagent addition module to achieve rapid switching between the two forms of reagents, avoiding equipment downtime due to process adjustments and improving production continuity.

[0019] By setting up a crystallization processing mechanism and adopting a continuous production process formed by multiple unit equipment, the preceding process creates excellent conditions for the subsequent process, avoids quality problems caused by process disconnection, thereby improving the stability of product quality and significantly improving production efficiency.

[0020] To more clearly illustrate the structural features and effects of the present invention, the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of an embodiment of the invention.

[0022] Figure 2 This is a side view of an embodiment of the invention.

[0023] Figure 3 This is a cross-sectional view of the interior of the pretreatment box in an embodiment of the invention.

[0024] Figure 4 This is a cross-sectional view of the interior of the crystallization processing box in an embodiment of the invention.

[0025] Figure 5 This is a schematic diagram of the connection structure between the first turntable and the second turntable in an embodiment of the invention.

[0026] Figure 6 This is a schematic diagram of the connection structure of the feed tube in an embodiment of the invention.

[0027] Figure 7 for Figure 6 A magnified structural diagram of A in the diagram.

[0028] Figure 8 This is a schematic diagram of the connection structure of the slip ring in an embodiment of the invention.

[0029] Figure 9 This is a cross-sectional view of the interior of the mounting base in an embodiment of the invention.

[0030] Figure 10 for Figure 9 A magnified structural diagram of B in the diagram.

[0031] Figure 11 This is a schematic diagram of the connection structure inside the mounting base in an embodiment of the invention.

[0032] Figure 12 This is a cross-sectional view of the infusion cylinder in an embodiment of the invention.

[0033] Reference numerals: 1. Support platform; 2. Support foot; 3. Pretreatment box; 4. Inlet pipe; 5. Filter screen; 6. Plate preheater; 7. Low-temperature vacuum evaporator; 8. First liquid guide pipe; 9. Pump body; 10. Second liquid guide pipe; 11. Crystallization treatment box; 12. Solid reagent feeding pipe; 13. First turntable; 14. Second turntable; 15. Feed guide pipe; 16. First rotating shaft; 17. Connecting plate; 18. Sealing plate; 19. Slip ring; 20. Feed guide groove; 21. Fixed pipe; 22. Fixed rod; 23. Mounting base; 24. Second rotating shaft; 25. Fixed plate; 26. Rotating gear; 27. Incomplete gear; 28. Third rotating shaft. 29. Rotating shaft; 30. Third turntable; 31. One-way bearing; 32. Rotating guide block; 33. Worm gear; 34. Worm; 35. Motor; 36. Synchronous belt; 37. Stirring shaft; 38. Stirring blade; 39. Anchor-type stirring paddle; 40. Push plate; 41. Wedge block; 42. Piston rod; 43. Piston plate; 44. Return spring; 45. Infusion cylinder; 46. Third liquid guide pipe; 47. First one-way valve; 48. Fourth liquid guide pipe; 49. Second one-way valve; 50. Liquid storage tank; 51. Connecting plate; 52. Gradient cooling device; 53. Solid-liquid separator; 54. Washer; 55. Vacuum dryer; 56. Sieve; 57. Discharge pipe. Detailed Implementation

[0034] To make the objectives, technical solutions, and advantages of this invention clearer, the invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the invention.

[0035] The specific implementation of the present invention will be described in detail below with reference to specific embodiments. Example

[0036] See Figures 1 to 11 A high-efficiency crystallization device for p-hydroxyacetophenone includes a support platform 1, a pretreatment tank 3 for pretreatment is mounted on the support platform 1, an inlet pipe 4 is connected to the pretreatment tank 3, a low-temperature vacuum evaporator 7 is connected below the pretreatment tank 3, and the low-temperature vacuum evaporator 7 is connected to a crystallization tank 11 through a pump body 9. The device also includes: A solid reagent adding mechanism is installed inside the crystallization treatment box 11 to add solid reagents quantitatively into the crystallization treatment box 11. The solid reagent adding mechanism includes a first turntable 13, a second turntable 14 and a guide pipe 15 for feeding control. The first turntable 13 is fixedly connected to the second turntable 14 through the guide pipe 15, and both the first turntable 13 and the second turntable 14 are rotatably connected to the inside of the crystallization treatment box 11 through a second rotating shaft 24. A sealing plate 18 for sealing is movably installed on one side of the lower end of the guide pipe 15. The sealing plate 18 is opened and closed by connecting with a slip ring 19.

[0037] Furthermore, the solid agent addition mechanism also includes a solid agent feeding pipe 12 for solid material feeding docking. A screw feeder is connected to the solid agent feeding pipe 12, and the solid agent feeding pipe 12 is fixedly installed on the crystallization treatment box 11. The slip ring 19 is fixedly installed on the fixed pipe 21 through the fixed rod 22, and the fixed pipe 21 is fixedly installed inside the crystallization treatment box 11 through the mounting base 23.

[0038] Furthermore, the solid agent addition mechanism also includes a docking plate 17 for controlling the feeding of the sealing plate 18. The docking plate 17 is fixedly installed on one side of the sealing plate 18. The docking plate 17 is rotatably connected to the guide tube 15 through the first rotating shaft 16. The slip ring 19 is provided with a feeding guide groove 20 for adapting to the rotational connection of the sealing plate 18, and the docking plate 17 is adapted to slide on the slip ring 19 and the feeding guide groove 20.

[0039] Furthermore, the solid agent addition mechanism also includes an incomplete gear 27 and a rotating gear 26 for driving the feed tube 15 to rotate and engage. The second rotating shaft 24 is rotatably mounted on the fixed plate 25, and the fixed plate 25 is fixedly mounted inside the mounting base 23. One end of the second rotating shaft 24 is fixedly connected to the rotating gear 26, and the incomplete gear 27 is meshed on the rotating gear 26. The incomplete gear 27 and the rotating gear 26 have the same diameter, and the number of teeth on the incomplete gear 27 is equal to half the number of teeth on the rotating gear 26.

[0040] Furthermore, the solid drug addition mechanism also includes a motor 34 for driving the incomplete gear 27 to rotate. The incomplete gear 27 is rotatably connected to the inside of the mounting base 23 via a third rotating shaft 28. A worm gear 32 is fixedly connected to the third rotating shaft 28, and a worm 33 is meshed on the worm gear 32. The worm 33 is fixedly connected to the output shaft of the motor 34, and the motor 34 is fixedly installed inside the mounting base 23.

[0041] Furthermore, the third rotating shaft 28 is synchronously connected to the stirring shaft 36 via the synchronous belt 35, and the stirring shaft 36 is fixedly connected to the stirring blade 37 and the anchor-type stirring paddle 38 for mixing.

[0042] Furthermore, the pretreatment box 3 is equipped with a filter screen 5 and a plate preheater 6. The low-temperature vacuum evaporator 7 is connected to a pump body 9 through a first liquid guide pipe 8. The pump body 9 is connected to the interior of the crystallization treatment box 11 through a second liquid guide pipe 10. The bottom of the support platform 1 is equipped with support feet 2 for support.

[0043] Preferably, during the crystallization process of p-hydroxyacetophenone, the inlet pipe 4 introduces the crude p-hydroxyacetophenone solution into the pretreatment tank 3, where the filter screen 5 filters the solution, the plate preheater 6 preheats the solution at a low temperature, and then the solution is evaporated by the low-temperature vacuum evaporator 7. The pump body 9 draws the concentrated liquid through the first liquid guide pipe 8 and then injects it into the crystallization tank 11 through the second liquid guide pipe 10.

[0044] According to the requirements of crystallization, when the solid reagent for crystallization needs to be added into the crystallization treatment box 11, the output shaft of the motor 34 drives the worm 33 to rotate in the forward direction. Under the meshing connection between the worm 33 and the worm wheel 32, the incomplete gear 27 on the third rotating shaft 28 rotates. Under the unidirectional control of the one-way bearing 30, the third turntable 29 does not rotate at this time. Therefore, under the meshing connection between the incomplete gear 27 and the rotating gear 26, the first turntable 13 and the second turntable 14 on the second rotating shaft 24 rotate half a revolution. The positions of the two guide pipes 15 are switched accordingly. Under the limiting action of the slip ring 19, the guide pipe 15 that reaches the solid agent discharge pipe 12 receives the material through the screw feeder connected to the solid agent discharge pipe 12. At this time, the guide pipe 15 that has received the material opens the sealing plate 18 on the guide pipe 15 under the sliding action of the discharge guide groove 20 on the slip ring 19 and the docking plate 17, so as to facilitate the discharge of the received solid agent and facilitate the addition of solid agent to the interior of the crystallization treatment box 11.

[0045] More importantly, due to the rotation of the third rotating shaft 28, the stirring blades 37 and the anchor-type stirring paddle 38 on the stirring shaft 36 can be driven to perform stirring under the synchronous transmission of the synchronous belt 35, thereby further improving the crystallization efficiency of p-hydroxyacetophenone. Example

[0046] like Figures 1-12 As shown, this embodiment, based on embodiment 1, also includes a liquid drug addition mechanism, which is installed inside the mounting base 23 and is connected and driven by the solid drug addition mechanism. It is used to add liquid drugs quantitatively into the crystallization treatment box 11. The liquid drug addition mechanism includes a third turntable 29 for liquid dispensing control and a delivery cylinder 44. The delivery cylinder 44 is connected to a third liquid guide pipe 45 for liquid dispensing. The delivery cylinder 44 performs liquid addition processing through the forward and reverse rotation of the third turntable 29.

[0047] Furthermore, the liquid medicine adding mechanism also includes a rotating guide block 31 and a wedge block 40 for driving the push plate 39 on the infusion cylinder 44 to reciprocate. The rotating guide block 31 is fixedly installed on the non-central side of the third turntable 29. The third turntable 29 is installed on the third rotating shaft 28 through a one-way bearing 30. The push plate 39 is provided with a wedge block 40 that is adapted to slide and connected with the rotating guide block 31. A return spring 43 is provided at the connection between the push plate 39 and the infusion cylinder 44.

[0048] Furthermore, the liquid drug addition mechanism also includes a piston plate 42 for driving the infusion cylinder 44 to connect to the liquid supply and a storage tank 49. The push plate 39 is fixedly connected to the piston plate 42 via the piston rod 41. The piston plate 42 is slidably connected to the inside of the infusion cylinder 44 and the infusion cylinder 44 is fixedly installed on the fixed pipe 21 via the connecting plate 50. The infusion cylinder 44 is fixedly connected to a third liquid guide pipe 45 and a fourth liquid guide pipe 47. A first one-way valve 46 is provided on the third liquid guide pipe 45 and a second one-way valve 48 is provided on the fourth liquid guide pipe 47. One end of the fourth liquid guide pipe 47 is connected to the storage tank 49, and the storage tank 49 is fixedly installed on the outside of the crystallization treatment box 11.

[0049] Preferably, in this embodiment, when liquid reagent needs to be added to the interior of the crystallization treatment box 11, the motor 34 drives the worm gear 33 to rotate in the opposite direction. At this time, under the unidirectional action of the one-way bearing 30, the rotating guide block 31 on the third turntable 29 can be driven to rotate synchronously. Figure 9 and Figure 10The structure shown is driven by clockwise rotation. Under the sliding connection of the rotating guide block 31 and the wedge block 40 and the reset action of the return spring 43, the piston plate 42 is driven to reciprocate inside the infusion cylinder 44. Then, under the one-way control of the first one-way valve 46 on the third infusion pipe 45 and the second one-way valve 48 on the fourth infusion pipe 47, the liquid agent in the storage tank 49 can be drawn and injected into the crystallization treatment tank 11. Thus, the agent can be selectively added according to the crystallization requirements of p-hydroxyacetophenone, further improving the processing efficiency.

[0050] It should be noted that the output shaft of motor 34 can be driven in both forward and reverse directions.

[0051] During the crystallization process of p-hydroxyacetophenone, problems such as unstable crystal form, uneven particle size distribution, and difficulty in achieving the required purity are often encountered. The solid reagents (such as specific seed crystals and adsorption-type purification agents) used in this invention can be added to induce the growth of the target crystal form in a directional manner and inhibit the crystallization of impurities. The addition of liquid reagents (such as crystallizing agents and dispersants) can quickly disperse in the liquid, adjust the viscosity and interfacial tension of the system, and solve the problem of crystal agglomeration caused by excessively slow or fast crystallization rates.

[0052] Therefore, the equipment can flexibly switch the form of the reagent according to process parameters such as liquid concentration, temperature, and stirring rate. When the liquid is in a high viscosity state, the liquid reagent is easier to mix evenly, avoiding local concentration imbalance caused by the agglomeration of solid reagent. When a long-term stable crystallization system is required, solid reagent (such as slow-release seed crystals) can extend the action period, reduce the frequency of replenishment, and adapt to intermittent and continuous production processes.

[0053] Solid reagents require less dosage and have high stability, eliminating the need for additional dissolving devices and reducing energy consumption. Liquid reagents can be injected via the infusion cylinder 44, enabling automated control and reducing human error. Therefore, the equipment in this application achieves rapid switching between the two forms of reagents by integrating a reagent addition module, avoiding equipment downtime due to process adjustments and improving production continuity. Example

[0054] like Figures 1-4 As shown, this embodiment, based on the above embodiment, also includes a crystallization processing mechanism, which is installed at one side connection of the crystallization processing box 11 and is used for the step-by-step crystallization processing of p-hydroxyacetophenone.

[0055] Furthermore, the crystallization processing mechanism includes a gradient cooler 51 for docking with the crystallization processing box 11. A solid-liquid separator 52 is docked on the gradient cooler 51. A scrubber 53 is docked on the solid-liquid separator 52. A vacuum dryer 54 is docked on the scrubber 53. A sieve 55 is docked on the vacuum dryer 54. A discharge pipe 56 for discharging material is provided on the sieve 55. The sieve 55 is fixedly installed on the support platform 1.

[0056] Preferably, in this embodiment, the mixed solution is then subjected to gradient cooling by a gradient cooler 51, followed by solid-liquid separation by a solid-liquid separator 52, then washing by a scrubber 53, then vacuum drying by a vacuum dryer 54, and finally sieve out the standard crystals by a sieve 55, thereby completing the crystallization process of p-hydroxyacetophenone, meeting the needs of industrial production, and facilitating processing and use.

[0057] This continuous production process, formed by multiple unit devices, creates favorable conditions for subsequent processes, avoids quality problems caused by process disconnection, thereby improving product quality stability and significantly increasing production efficiency.

[0058] It should be noted that the components in this application are all general standard parts or parts known to those skilled in the art, which effectively solve the technical problems raised in the background art.

[0059] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A high-efficiency crystallization device for p-hydroxyacetophenone, comprising a support table (1), characterized in that, The support table (1) is provided with a pretreatment box (3) for pretreatment, the pretreatment box (3) is communicated with a liquid inlet pipe (4), the lower portion of the pretreatment box (3) is connected with a low-temperature vacuum evaporator (7), the low-temperature vacuum evaporator (7) is communicated with a crystallization treatment box (11) through a pump body (9), and the crystallization treatment box (11) is further provided with: A solid medicine adding mechanism is installed in the interior of the crystallization treatment box (11) and is used for quantitatively adding solid medicine into the interior of the crystallization treatment box (11), the solid medicine adding mechanism comprises a first rotating disc (13) for controlling the discharging, a second rotating disc (14) and a material guide pipe (15), the second rotating disc (14) is fixedly connected with the first rotating disc (13) through the material guide pipe (15), and the first rotating disc (13) and the second rotating disc (14) are both rotationally connected to the interior of the crystallization treatment box (11) through a second rotating shaft (24), a sealing plate (18) for sealing is movably installed on one side of the lower end of the material guide pipe (15), and the sealing plate (18) is controlled to open and close through the connection with a slip ring (19); A liquid medicine adding mechanism is installed in the interior of the mounting seat (23) and is connected and driven by the solid medicine adding mechanism, and is used for quantitatively adding liquid medicine into the interior of the crystallization treatment box (11), the liquid medicine adding mechanism comprises a third rotating disc (29) for controlling the liquid outlet and a liquid delivery cylinder (44), the liquid delivery cylinder (44) is communicated with a third liquid guide pipe (45) for liquid outlet, and the liquid delivery cylinder (44) is treated with liquid feeding through the forward and reverse rotation of the third rotating disc (29); A crystallization treatment mechanism is installed at one side of the crystallization treatment box (11) and is used for gradually crystallizing hydroxyacetophenone.

2. The efficient crystallization apparatus of the p-hydroxyacetophenone according to claim 1, characterized by, The solid medicine adding mechanism further comprises a solid medicine discharging pipe (12) for the butt joint of solid discharging, the solid medicine discharging pipe (12) is connected with a spiral discharging machine, and the solid medicine discharging pipe (12) is fixedly installed on the crystallization treatment box (11), the slip ring (19) is fixedly installed on a fixed pipe (21) through a fixed rod (22), and the fixed pipe (21) is fixedly installed in the interior of the crystallization treatment box (11) through the mounting seat (23).

3. The high-efficiency crystallization apparatus of the para-hydroxyacetophenone according to claim 2, characterized by, The solid medicine adding mechanism further comprises a butt joint plate (17) for driving the sealing plate (18) to control the discharging, the butt joint plate (17) is fixedly installed on one side of the sealing plate (18), the butt joint plate (17) is rotationally connected to the material guide pipe (15) through a first rotating shaft (16), and the slip ring (19) is provided with a discharging guide groove (20) for adapting the rotational connection of the sealing plate (18), and the butt joint plate (17) is adaptively and slidingly connected to the slip ring (19) and the discharging guide groove (20).

4. The efficient crystallization apparatus of the p-hydroxyacetophenone according to claim 3, characterized by, The solid medicine adding mechanism further comprises an incomplete gear (27) and a rotating gear (26) for driving the guide pipe (15) to rotate and dock, the second rotating shaft (24) is rotatably installed on a fixed plate (25), the fixed plate (25) is fixedly installed inside the mounting seat (23), one end of the second rotating shaft (24) is fixedly connected with the rotating gear (26), the rotating gear (26) is in meshing connection with the incomplete gear (27), the diameters of the incomplete gear (27) and the rotating gear (26) are the same, and the number of teeth on the incomplete gear (27) is equal to half of the number of teeth on the rotating gear (26).

5. The efficient crystallization apparatus of the p-hydroxyacetophenone according to claim 4, characterized by, The solid medicine adding mechanism further comprises a motor (34) for driving the incomplete gear (27) to rotate, the incomplete gear (27) is rotatably connected to the inside of the mounting seat (23) through a third rotating shaft (28), the third rotating shaft (28) is fixedly connected with a worm gear (32), the worm gear (32) is in meshing connection with a worm (33), the worm (33) is fixedly connected with an output shaft of the motor (34), and the motor (34) is fixedly installed inside the mounting seat (23).

6. The efficient crystallization apparatus of the p-hydroxyacetophenone according to claim 5, characterized by, The third rotating shaft (28) is synchronously rotatably connected with a stirring shaft (36) through a synchronous belt (35), the stirring shaft (36) is fixedly connected with stirring blades (37) and anchor stirring paddles (38) for mixing and stirring.

7. The efficient crystallization apparatus of the para-hydroxyacetophenone according to claim 1, characterized by, The liquid medicine adding mechanism further comprises a rotating guide block (31) and a wedge block (40) for driving the push plate (39) on the infusion cylinder (44) to move back and forth, the rotating guide block (31) is fixedly installed at a non-central side position on a third rotating disc (29), the third rotating disc (29) is installed on the third rotating shaft (28) through a one-way bearing (30), the wedge block (40) is arranged on the push plate (39) in sliding connection with the rotating guide block (31), and a return spring (43) is arranged at the connection position of the push plate (39) and the infusion cylinder (44).

8. The efficient crystallization apparatus of the p-hydroxyacetophenone according to claim 7, characterized by, The liquid medicine adding mechanism further comprises a piston plate (42) and a liquid storage tank (49) for driving the infusion cylinder (44) to supply liquid, the push plate (39) is fixedly connected with the piston plate (42) through a piston rod (41), the piston plate (42) is limitingly and slidably connected inside the infusion cylinder (44), the infusion cylinder (44) is fixedly installed on the fixed pipe (21) through a connecting plate (50), the infusion cylinder (44) is fixedly and communicatively connected with a third liquid guide pipe (45) and a fourth liquid guide pipe (47), a first one-way valve (46) is arranged on the third liquid guide pipe (45), a second one-way valve (48) is arranged on the fourth liquid guide pipe (47), one end of the fourth liquid guide pipe (47) is communicated with the liquid storage tank (49), and the liquid storage tank (49) is fixedly installed outside the crystallization treatment tank (11).

9. The efficient crystallization apparatus of the para-hydroxyacetophenone according to claim 1, characterized by, The crystallization treatment mechanism comprises a gradient temperature reducer (51) for docking a crystallization treatment box (11), a solid-liquid separator (52) is docked on the gradient temperature reducer (51), a washing device (53) is docked on the solid-liquid separator (52), a vacuum dryer (54) is docked on the washing device (53), and a screening device (55) is docked on the vacuum dryer (54), a discharge pipe (56) for discharging is arranged on the screening device (55), and the screening device (55) is fixedly installed on the support table (1).

10. The efficient crystallization apparatus of the p-hydroxyacetophenone according to claim 1, characterized by, The pre-treatment box (3) is provided with a filter screen (5) and a plate pre-heater (6), the low-temperature vacuum evaporator (7) is connected with a pump body (9) through a first liquid guide pipe (8), the pump body (9) is communicated with the inside of the crystallization treatment box (11) through a second liquid guide pipe (10), and the bottom of the support table (1) is provided with support feet (2) for supporting.

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