A strain of Acanthamoeba that inhibits Fusarium graminearum and its application

By culturing and applying the Acanthamoeba NJAU-ZY1, the problem of the lack of inhibition of Fusarium graminearum in existing technologies has been solved, achieving effective inhibition of Fusarium graminearum and prevention and control of wheat scab, thus protecting the soil micro-ecosystem.

CN121574829BActive Publication Date: 2026-05-26SANYA INSTITUTE OF NANJING AGRICULTURAL UNIVERSITY
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Patent Information

Application Number
CN202610070058.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2026-01-20
Publication Date
2026-05-26
Estimated Expiration
2046-01-20

AI Technical Summary

Technical Problem

The lack of effective protozoa in existing technologies to suppress Fusarium graminearum pathogens leads to frequent pesticide use, which has a negative impact on the environment and soil microbial diversity, making it difficult to balance disease control and ecological benefits.

Method used

Using the Acanthamoeba protozoan NJAU-ZY1, inactivated microorganisms were added to PAS culture medium as food, and the mixture was cultured and applied to soil to inhibit Fusarium graminearum, thus preparing a product for the prevention and control of wheat scab.

Benefits of technology

It significantly inhibits the mycelial growth of Fusarium graminearum, reduces the number of spores, decreases its ability to infect wheat, alleviates Fusarium head blight, and protects the soil micro-ecosystem.

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Abstract

This invention discloses a strain of Acanthamoeba that inhibits the pathogen of Fusarium graminearum and its applications. Acanthamoeba (Acanthamoeba rhysodes NJAU-ZY1, deposited at the China Center for Type Culture Collection (CCTCC) with accession number CCTCC NO: C2025219, demonstrates in plate experiments, liquid co-culture experiments, and pot experiments that inoculation with the protozoan Acanthamoeba NJAU-ZY1 significantly inhibits the growth of Fusarium graminearum pathogen, reduces its infectivity in wheat, alleviates the inhibitory effect of Fusarium graminearum on wheat growth, reduces the risk of diseases caused by this pathogen, and thus increases wheat biomass. This provides a new strategy and resource for the biological control of Fusarium graminearum pathogen and the scientific cultivation of wheat, and has important application value for the safe production of food crops.
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