Intelligently and quantitatively controlled intestinal tract targeted drug delivery device

Abstract

The invention relates to the technical field of intelligent quantitative control of intestinal targeted drug delivery devices, in particular to an intelligent quantitative control intestinal targeted drug delivery device which comprises a drug box. The intestinal pressure value feedback unit is located outside the medicament box; the intestinal tract pH value feedback unit is located outside the medicament box, and the intestinal tract temperature value feedback unit is located outside the medicament box. A first dosing pump pumps a medicament in a medicament box to a first dosing output end for dosing through a first dosing tube and a second dosing tube, and a first intestinal pressure value sensor is arranged, so that a pressure value in the intestinal tract of a user can be conveniently detected and displayed in a first pressure value screen display area; a medical worker can compare a pressure numerical value in the intestinal tract of a user with a rated intestinal tract pressure threshold value, then the first drug delivery amount control area is used for conducting drug adding or drug reducing control, and a second drug delivery pump pumps drugs in a drug box to a second drug delivery output end through a first drug delivery pipe and a third drug delivery barrel for drug delivery.

Description

Technical Field

[0001] This invention relates to the field of intelligent quantitative control technology for intestinal targeted drug delivery devices, specifically to an intelligent quantitative control intestinal targeted drug delivery device. Background Technology

[0002] Intestinal targeted drug delivery devices are a type of drug delivery device specifically designed for the precise release of drugs at specific sites in the intestine. Their core objective is to increase local drug concentration in the intestine and reduce systemic side effects, while adapting to the delivery needs of different dosage forms. They integrate three core technologies: targeted localization, quantitative control, and biocompatibility. Unlike the "random release" of ordinary oral formulations, they can release drugs at specific points, in specific quantities, and at specific times through passive response or active control. Intestinal targeted drug delivery devices are a new type of drug delivery device specifically designed for the precise release of drugs at specific sites in the intestine. Their core function is to address the pain points of traditional oral formulations—"random release, significant systemic side effects, and poor absorption of large molecule drugs"—through targeted localization, physiological parameter sensing, and intelligent quantitative control technologies, thereby achieving precise, individualized, and safe treatment of local intestinal diseases.

[0003] In existing technologies, if the intestinal targeted drug delivery dosage does not integrate key physiological parameters such as intestinal pressure, pH, and temperature, it can lead to loss of control over drug delivery accuracy, failure of targeting, and even decreased efficacy or adverse reactions. Summary of the Invention

[0004] The purpose of this invention is to provide an intelligent quantitative control intestinal targeted drug delivery device to solve the problem mentioned in the background art, where if the intestinal targeted drug delivery dosage does not integrate key physiological parameters such as intestinal pressure, pH, and temperature, it will lead to loss of drug delivery accuracy, failure of targeting, and even reduced efficacy or adverse reactions.

[0005] To achieve the above objectives, the present invention provides the following technical solution: an intelligent quantitatively controlled intestinal targeted drug delivery device, comprising:

[0006] A medicine box for storing medications used for targeted intestinal drug delivery;

[0007] An intestinal pressure feedback unit is located outside the medicine box. The intestinal pressure feedback unit includes a first drug delivery pump. A drug delivery tube locking ring is fixedly installed on one side of the medicine box. A first drug delivery tube is fixedly installed inside the drug delivery tube locking ring. A first controller is fixedly installed below the first drug delivery pump. A first intestinal pressure sensor is installed below the first controller. The first controller is signal-connected to the first drug delivery pump and the first controller is signal-connected to the first intestinal pressure sensor.

[0008] An intestinal pH feedback unit is located outside the medicine box. The intestinal pH feedback unit includes a second drug delivery pump, a second controller is fixedly installed below the second drug delivery pump, and a second intestinal pH sensor is installed below the second controller. The second controller is signal-connected to the second drug delivery pump and the second controller is signal-connected to the second intestinal pH sensor.

[0009] An intestinal temperature feedback unit is located outside the medicine box. The intestinal temperature feedback unit includes a third drug delivery pump, a third controller is fixedly installed below the third drug delivery pump, and a third intestinal temperature sensor is installed below the third controller. The third controller is signal-connected to the third drug delivery pump and the third intestinal temperature sensor.

[0010] Preferably, the first administration tube and the first administration pump are fixedly connected by a second administration cylinder, and a first solenoid valve is provided on the side of the second administration cylinder near the first administration pump. A first connecting seat is provided between the first administration pump and the first controller.

[0011] Preferably, a first drug delivery output terminal is fixedly provided on the top of the first drug delivery pump, the first controller is connected to the first intestinal pressure sensor through a signal cable, a first control panel is fixedly provided on the outside of the first controller, a pressure value display area is fixedly provided on the outside of the first control panel, and a drug delivery control area is fixedly provided on the outside of the first control panel.

[0012] Preferably, the first administration tube and the second administration pump are fixedly connected by a third administration cylinder, and a second solenoid valve is provided on the side of the third administration cylinder near the second administration pump, and a second connecting seat is provided between the second administration pump and the second controller.

[0013] Preferably, a second drug delivery output terminal is fixedly provided on the top of the second drug delivery pump, the second controller is connected to the second intestinal pH sensor through a signal cable, a second control panel is fixedly provided on the outside of the second controller, a pH display area is fixedly provided on the outside of the second control panel, and a drug delivery control area is fixedly provided on the outside of the second control panel.

[0014] Preferably, the first administration tube and the third administration pump are fixedly connected by a fourth administration cylinder, and a third solenoid valve is provided on the side of the fourth administration cylinder near the third administration pump. A third connecting seat is provided between the third administration pump and the third controller.

[0015] Preferably, a third drug delivery output terminal is fixedly provided on the top of the third drug delivery pump, the third controller is connected to the third intestinal temperature sensor via a signal cable, a third control panel is fixedly provided on the outside of the third controller, a temperature display area is fixedly provided on the outside of the third control panel, and a drug delivery control area is fixedly provided on the outside of the third control panel.

[0016] Compared with the prior art, the beneficial effects of the present invention are:

[0017] The present invention comprises a first drug delivery pump that draws medication from the medicine tank to the first drug delivery outlet via a first drug delivery tube and a second drug delivery cylinder. A first intestinal pressure sensor facilitates the detection of pressure values ​​within the user's intestines, which are displayed on a pressure value display area. Medical personnel can compare the user's intestinal pressure value with a rated intestinal pressure threshold and then use the infusion control area to adjust the dosage. A second drug delivery pump, via the first drug delivery tube and a third drug delivery cylinder, draws medication from the medicine tank to the second drug delivery outlet. A second intestinal pH sensor facilitates the monitoring of the pH value within the user's intestines. The pH value is detected and displayed in the second pH display area. Medical personnel can compare the pH value inside the user's intestine with the rated intestinal pH threshold, and then use the second infusion control area to control the addition or reduction of medication. The third drug delivery pump draws the medication from the medicine box to the third drug delivery output end through the first drug delivery tube and the fourth drug delivery cylinder for drug delivery. The third intestinal temperature sensor is set up to facilitate the detection of the temperature value inside the user's intestine, which is displayed in the third temperature display area. Medical personnel can compare the temperature value inside the user's intestine with the rated intestinal temperature threshold, and then use the third infusion control area to control the addition or reduction of medication.

[0018] This invention achieves real-time monitoring and dynamic dosage calibration of intestinal pressure, pH, and temperature through three independent sensing and drug delivery control. By using independent sensing, zoned control, and closed-loop feedback, it realizes "precision, individualization, and safety" of targeted drug delivery to the intestine. The three independent sensing modules for pressure, pH, and temperature collect physiological parameters of different target areas in the intestine in real time. Combined with the zoned drug delivery control unit, the sensing data is compared with preset thresholds to dynamically adjust the drug delivery dosage and release timing of the corresponding channels. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0020] Figure 2 This is a schematic diagram of the control structure of the present invention;

[0021] Figure 3This is a three-dimensional structural diagram of the intestinal pressure value feedback unit of the present invention;

[0022] Figure 4 This is a three-dimensional structural diagram of the intestinal pH feedback unit of the present invention;

[0023] Figure 5 This is a partial three-dimensional structural diagram of the present invention. Figure 1 ;

[0024] Figure 6 This is a partial three-dimensional structural diagram of the present invention. Figure 2 .

[0025] In the picture:

[0026] 1. Medicine box; 2. Dosing tube locking ring; 3. First dosing tube;

[0027] 4. Intestinal pressure feedback unit; 401. Second drug delivery cylinder; 402. First solenoid valve; 403. First drug delivery pump; 404. First connector; 405. First drug delivery output terminal; 406. First controller; 407. First control panel; 4071. Pressure value display area 1; 4072. Drug delivery control area 1; 408. Signal cable 1; 409. First intestinal pressure sensor;

[0028] 5. Intestinal pH feedback unit; 501. Third drug delivery cartridge; 502. Second solenoid valve; 503. Second drug delivery pump; 504. Second connector; 505. Second drug delivery output terminal; 506. Second controller; 507. Second control panel; 5071. pH display area two; 5072. Drug delivery control area two; 508. Signal cable two; 509. Second intestinal pH sensor;

[0029] 6. Intestinal temperature feedback unit; 601. Fourth drug delivery cylinder; 602. Third solenoid valve; 603. Third drug delivery pump; 604. Third connector; 605. Third drug delivery output terminal; 606. Third controller; 607. Third control panel; 6071. Temperature display area three; 6072. Drug delivery control area three; 608. Signal cable three; 609. Third intestinal temperature sensor. Detailed Implementation

[0030] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. This application will now be described in detail with reference to the accompanying drawings and embodiments.

[0031] To enable those skilled in the art to better understand the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present application, and not all embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative effort should fall within the scope of protection of the present application.

[0032] like Figures 1-6 As shown, this application provides an intelligent quantitative control intestinal targeted drug delivery device, including: a drug tank 1 for storing drugs for intestinal targeted drug delivery.

[0033] In this embodiment: the intestinal pressure value feedback unit 4 is located outside the medicine box 1. The intestinal pressure value feedback unit 4 includes a first drug delivery pump 403. A drug delivery tube locking ring 2 is fixedly installed on one side of the medicine box 1. A first drug delivery tube 3 is fixedly installed on the inner side of the drug delivery tube locking ring 2. A first controller 406 is fixedly installed below the first drug delivery pump 403. A first intestinal pressure value sensor 409 is installed below the first controller 406. The first controller 406 is signal-connected to the first drug delivery pump 403 and the first intestinal pressure value sensor 409.

[0034] Specifically, such as Figures 1-6 As shown, the first administration tube 3 and the first administration pump 403 are fixedly connected by the second administration cylinder 401. The second administration cylinder 401 is provided with a first solenoid valve 402 on the side near the first administration pump 403. The first administration pump 403 and the first controller 406 are provided with a first connecting seat 404. The top of the first administration pump 403 is fixedly provided with a first administration output terminal 405. The first controller 406 and the first intestinal pressure value sensor 409 are connected by a signal cable 408. The outside of the first controller 406 is fixedly provided with a first control panel 407. The outside of the first control panel 407 is fixedly provided with a pressure value display area 4071 and a drug delivery control area 4072.

[0035] In this embodiment: the intestinal pH feedback unit 5 is located outside the medicine box 1. The intestinal pH feedback unit 5 includes a second drug delivery pump 503. A second controller 506 is fixedly disposed below the second drug delivery pump 503. A second intestinal pH sensor 509 is disposed below the second controller 506. The second controller 506 is signal-connected to the second drug delivery pump 503 and the second intestinal pH sensor 509.

[0036] Specifically, such as Figures 1-6As shown, the first administration tube 3 and the second administration pump 503 are fixedly connected by a third administration cylinder 501. A second solenoid valve 502 is provided on the side of the third administration cylinder 501 near the second administration pump 503. A second connector 504 is provided between the second administration pump 503 and the second controller 506. A second administration output terminal 505 is fixedly provided on the top of the second administration pump 503. The second controller 506 and the second intestinal pH sensor 509 are connected by a signal cable 508. A second control panel 507 is fixedly provided on the outside of the second controller 506. A second pH display area 5071 is fixedly provided on the outside of the second control panel 507. A second infusion rate control area 5072 is fixedly provided on the outside of the second control panel 507.

[0037] In this embodiment: the intestinal temperature feedback unit 6 is located outside the medicine box 1. The intestinal temperature feedback unit 6 includes a third drug delivery pump 603, a third controller 606 is fixedly disposed below the third drug delivery pump 603, and a third intestinal temperature sensor 609 is disposed below the third controller 606. The third controller 606 is signal-connected to the third drug delivery pump 603, and the third controller 606 is signal-connected to the third intestinal temperature sensor 609. Specifically, as shown... Figures 1-6 As shown, the first administration tube 3 and the third administration pump 603 are fixedly connected by the fourth administration cylinder 601. The fourth administration cylinder 601 is provided with a third solenoid valve 602 on the side near the third administration pump 603. The third administration pump 603 and the third controller 606 are provided with a third connector 604. The top of the third administration pump 603 is fixedly provided with a third administration output terminal 605. The third controller 606 and the third intestinal temperature sensor 609 are connected by a signal cable 608. The outside of the third controller 606 is fixedly provided with a third control panel 607. The outside of the third control panel 607 is fixedly provided with a temperature display area 6071 and a drug delivery control area 6072.

[0038] Specifically, the solution is as follows: A first drug delivery pump 403 draws the medication from the medicine tank 1 to the first drug delivery output 405 via a first drug delivery tube 3 and a second drug delivery cylinder 401. A first intestinal pressure sensor 409 is installed to facilitate the detection of the pressure value inside the user's intestines, which is displayed on the pressure display area 4071. Medical personnel can compare the pressure value inside the user's intestines with the rated intestinal pressure threshold and then use the infusion control area 4072 to control the addition or reduction of medication. A second drug delivery pump 503 draws the medication from the medicine tank 1 to the second drug delivery output 505 via the first drug delivery tube 3 and the third drug delivery cylinder 501. A second intestinal pH sensor 509 is installed to facilitate the monitoring of the user's intestinal pH. The pH value of the intestinal tract is detected and displayed in the pH display area 5071. Medical personnel can compare the pH value inside the user's intestine with the rated intestinal pH threshold, and then use the infusion control area 5072 to control the addition or reduction of medication. The third drug delivery pump 603 draws the medication from the medicine tank 1 to the third drug delivery output end 605 through the first drug delivery tube 3 and the fourth drug delivery cylinder 601 for drug delivery. The third intestinal temperature sensor 609 is set to facilitate the detection of the temperature value inside the user's intestine, which is displayed in the temperature display area 6071. Medical personnel can compare the temperature value inside the user's intestine with the rated intestinal temperature threshold, and then use the infusion control area 6072 to control the addition or reduction of medication.

[0039] Those skilled in the art should understand that the discussion of any of the above embodiments is merely exemplary; within the framework of this invention, the technical features of the above embodiments or different embodiments can also be combined, the steps can be implemented in any order, and there are many other variations of the different aspects of the invention as described above, which are not provided in detail for the sake of brevity.

[0040] This invention is intended to cover all such substitutions, modifications, and variations that fall within the broad scope of the appended claims. Therefore, any omissions, modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this invention should be included within the scope of protection of this invention.

Claims

1. A smart dosing and controlling enteric targeting drug delivery device, characterized in that, Include: Medicine box (1) for storing medicine for intestinal targeted drug delivery; Intestinal pressure value feedback unit (4) located outside the medicine box (1), the intestinal pressure value feedback unit (4) includes a first drug pump (403), one side of the medicine box (1) is fixedly provided with a drug tube locking ring (2), the inner side of the drug tube locking ring (2) is fixedly provided with a first drug tube (3), the lower side of the first drug pump (403) is fixedly provided with a first controller (406), the lower side of the first controller (406) is provided with a first intestinal pressure value sensor (409), the first controller (406) is signal connected with the first drug pump (403), and the first controller (406) is signal connected with the first intestinal pressure value sensor (409); Intestinal pH value feedback unit (5) located outside the medicine box (1), the intestinal pH value feedback unit (5) includes a second drug pump (503), the lower side of the second drug pump (503) is fixedly provided with a second controller (506), the lower side of the second controller (506) is provided with a second intestinal pH value sensor (509), the second controller (506) is signal connected with the second drug pump (503), and the second controller (506) is signal connected with the second intestinal pH value sensor (509); Intestinal temperature value feedback unit (6) located outside the medicine box (1), the intestinal temperature value feedback unit (6) includes a third drug pump (603), the lower side of the third drug pump (603) is fixedly provided with a third controller (606), the lower side of the third controller (606) is provided with a third intestinal temperature value sensor (609), the third controller (606) is signal connected with the third drug pump (603), and the third controller (606) is signal connected with the third intestinal temperature value sensor (609).

2. The intelligent dosing and enteric targeting drug delivery device as claimed in claim 1, wherein, Wherein the first drug tube (3) and the first drug pump (403) are fixedly connected through the second drug cylinder (401), the side close to the first drug pump (403) of the second drug cylinder (401) is provided with a first electromagnetic valve (402), and the first drug pump (403) and the first controller (406) are provided with a first connecting seat (404).

3. The intelligent dosing and enteric targeting drug delivery device as claimed in claim 1, wherein, The top of the first drug pump (403) is fixedly provided with a first drug output end (405), the first controller (406) and the first intestinal pressure value sensor (409) are connected through a signal cable one (408), the outer side of the first controller (406) is fixedly provided with a first control panel (407), the outer side of the first control panel (407) is fixedly provided with a pressure value screen display area one (4071), and the outer side of the first control panel (407) is fixedly provided with a drug delivery amount control area one (4072).

4. The intelligent dosing and enteric targeting drug delivery device as claimed in claim 3, wherein, The first administration pipe (3) is fixedly connected with the second administration pump (503) through the third administration cylinder (501), one side of the third administration cylinder (501) close to the second administration pump (503) is provided with the second electromagnetic valve (502), and the second administration pump (503) is provided with the second connecting seat (504) between the second controller (506).

5. The intelligent dosing and enteric targeting drug delivery device as claimed in claim 1, wherein, The top of the second administration pump (503) is fixedly provided with the second administration output end (505), the second controller (506) is connected with the second intestinal pH value sensor (509) through the second signal cable (508), the outer side of the second controller (506) is fixedly provided with the second control panel (507), the outer side of the second control panel (507) is fixedly provided with the pH value screen display area two (5071), and the outer side of the second control panel (507) is fixedly provided with the medicine output control area two (5072).

6. The intelligent dosing and enteric targeting drug delivery device as claimed in claim 4, wherein, The first administration pipe (3) is fixedly connected with the third administration pump (603) through the fourth administration cylinder (601), one side of the fourth administration cylinder (601) close to the third administration pump (603) is provided with the third electromagnetic valve (602), and the third administration pump (603) is provided with the third connecting seat (604) between the third controller (606).

7. The intelligent dosing and enteric targeting drug delivery device as claimed in claim 1, wherein, The top of the third administration pump (603) is fixedly provided with the third administration output end (605), the third controller (606) is connected with the third intestinal temperature value sensor (609) through the third signal cable (608), the outer side of the third controller (606) is fixedly provided with the third control panel (607), the outer side of the third control panel (607) is fixedly provided with the temperature value screen display area three (6071), and the outer side of the third control panel (607) is fixedly provided with the medicine output control area three (6072).

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