Tibetan medicine composition for sanitary napkins and application of Tibetan medicine composition

Abstract

The invention discloses a Tibetan medicine composition for sanitary napkins and application of the Tibetan medicine composition, and belongs to the technical field of female hygienic products. Active components of the Tibetan medicine composition are prepared from the following raw materials in parts by weight: 10-30 parts of sweet clover, 15-35 parts of uncaria, 10-25 parts of picea palustris and 5-15 parts of halite. The preparation method comprises the following steps: respectively cleaning, selecting and crushing the sweet clover, the uncaria and the picea palustris, carrying out ultrasonic-assisted extraction by adopting an ethanol aqueous solution, filtering, combining an extracting solution, and concentrating to obtain an extract; and crushing halite, mixing with the extract, and performing spray drying to prepare powder. According to the invention, the traditional Tibetan medicine formula of five-herb conehead grass is innovatively applied to the sanitary napkin for the first time, the active ingredients of the medicine are reserved to the greatest extent through a scientific extraction process, and the obtained composition has remarkable effects of diminishing inflammation, sterilizing, resisting bacteria and relieving dysmenorrhea.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of female sanitary products, in particular to a Tibetan medicine composition for sanitary napkin and application thereof. BACKGROUND

[0002] Sanitary napkin is a daily hygiene product for adult women. The main function of the sanitary napkin on the market is to absorb menstrual blood and keep dry. However, during menstruation, the cervix is slightly open, the resistance is decreased, and the menstrual blood is a good culture medium for bacteria, which can easily cause various gynecological inflammations such as vaginitis and cervicitis. In order to meet the further needs of consumers for health functions, some health-care sanitary napkins with added traditional Chinese medicine ingredients have appeared on the market, such as motherwort and sophora flavescens.

[0003] Tibetan medicine is a treasure of traditional Chinese medicine, and has unique theory and rich experience in treating gynecological diseases. "Wuyi Shengtoucao" is a commonly used combination in the classic of Tibetan medicine for treating gynecological inflammation, which is mainly composed of melilotus officinalis, ramulus campylotropidis, picea wilsonii, and guangming salt. Melilotus officinalis has the effects of clearing heat, killing adhesion, detoxifying and anti-inflammatory; Ramulus campylotropidis can treat inflammation caused by "long" (a factor in the basic theory of Tibetan medicine) and virus; Picea wilsonii can detoxify and relieve swelling; and Guangming salt can digest and resolve accumulation, and regulate cold "peiguan".

[0004] However, there are many technical challenges in applying traditional Tibetan medicine formula to modern sanitary napkin products: first, how to maximize the extraction of effective components from medicinal materials by modern extraction technology and maintain their activity; second, how to integrate the extract into the specific structure of the sanitary napkin in a stable form to ensure that the medicinal effect can be continuously and safely released during use; third, a complete quality control and safety evaluation system needs to be established. In the prior art, the method of directly adding Tibetan medicine coarse powder to the sanitary napkin has the problems of low utilization rate of medicinal components, poor uniformity, easy migration and shedding, etc. Therefore, it is of great practical significance and market value to develop a Tibetan medicine composition for sanitary napkin based on Tibetan medicine formula, which has definite efficacy and is suitable for industrial production, and the application technology thereof.

[0005] Therefore, the present application provides a Tibetan medicine composition for sanitary napkin and application thereof. SUMMARY

[0006] The present application aims at solving the problems in the prior art and provides a Tibetan medicine composition for sanitary napkin and application thereof.

[0007] In order to achieve the above-mentioned purpose, the present application adopts the following technical scheme: A Tibetan medicine composition for sanitary napkin, which is composed of the following components in mass ratio: Melilotus officinalis 10-30 parts, Cistus canescens 15-25 parts, Picea brachytyla 10-25 parts, Salicornia europaea 5-15 parts.

[0008] Preferably: it is composed of the following mass ratio components: Melilotus officinalis 15-25 parts, Cistus canescens 20-30 parts, Picea brachytyla 15-20 parts, Salicornia europaea 8-12 parts.

[0009] Preferably: it is composed of the following mass ratio components: Melilotus officinalis 20 parts, Cistus canescens 25 parts, Picea brachytyla 18 parts, Salicornia europaea 10 parts.

[0010] A preparation method of a Tibetan medicine composition for sanitary napkins, comprising the following steps: S1: raw material pretreatment: take the required amount of Melilotus officinalis, Cistus canescens, and Picea brachytyla respectively, clean, dry, and then crush to 40-60 mesh, to obtain mixed medicine powder; separately crush Salicornia europaea to 100-150 mesh to obtain salt powder; S2: ultrasonic extraction: mix the mixed medicine powder with an ethanol solution with a concentration of 50%-70% at a solid-liquid ratio of 1:8-1:12 (g / mL), and perform ultrasonic extraction at 40-60°C, with an ultrasonic power of 300-500W, for an extraction time of 30-60 minutes, and extract 1-2 times; S3: concentration: combine all the extraction liquids of step S2, filter, and concentrate the filtrate under reduced pressure at 50-65°C and a vacuum degree of -0.06 to -0.08 MPa to a relative density of 1.10-1.20 at 60°C to obtain an extract; S4: mixing and drying: mix the salt powder obtained in step S1 with the extract obtained in step S3 uniformly, and perform spray drying with an inlet air temperature of 160-180°C and an outlet air temperature of 80-90°C to obtain the powder of the Tibetan medicine composition.

[0011] Preferably: in S2, the concentration of the ethanol solution is 60%, the solid-liquid ratio is 1:10 (g / mL), the ultrasonic temperature is 50°C, the ultrasonic power is 400W, the extraction time is 45 minutes, and the extraction is performed 2 times.

[0012] Preferably: in S4, the powder obtained after spray drying is sieved through an 80-100 mesh sieve.

[0013] The application of a Tibetan medicine composition for sanitary napkins in the preparation of female sanitary napkins with health care functions.

[0014] Preferably, the sanitary napkin comprises a top layer, an absorbent core layer, and a bottom layer, wherein the Tibetan medicine composition is evenly sprinkled in the absorbent core layer in powder form, and the amount added is 10-100 mg per sanitary napkin.

[0015] Preferably, the Tibetan medicine composition is made into microcapsules using an aqueous adhesive and then coated onto the surface nonwoven fabric of the sanitary napkin.

[0016] Preferably, its health care functions include at least one of anti-inflammatory, bactericidal, antibacterial, dysmenorrhea relief, or improvement of the private area environment.

[0017] The beneficial effects of this invention are as follows: Formula innovation: This invention is the first to systematically develop and apply the classic Tibetan medicine "Five Flavors of Herb" formula to sanitary napkin products, combining traditional Tibetan medicine wisdom with the health needs of modern women, and is an innovative inheritance of Tibetan medicine culture.

[0018] Advanced Technology: Utilizing ultrasound-assisted extraction technology, this method achieves a higher extraction rate of active ingredients, lower energy consumption, and shorter processing time compared to traditional decoction methods. Combined with spray drying technology, the resulting powder product exhibits uniform particle size, good flowability, and high stability, facilitating precise addition and uniform dispersion in subsequent sanitary napkin production lines.

[0019] Efficacy confirmation: By optimizing the formulation and extraction process, the synergistic effect of various active ingredients (such as flavonoids, phenolic acids, and mineral salts) in the composition is ensured, giving it clear anti-inflammatory, antibacterial and other biological activities, as demonstrated by in vitro pharmacodynamic experiments (see subsequent examples). Attached Figure Description

[0020] Figure 1 This is a flowchart illustrating the preparation process of a Tibetan medicine composition for sanitary napkins proposed in this invention. Detailed Implementation

[0021] The technical solution of the present invention will be further described in detail below with reference to specific embodiments.

[0022] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "setting" should be interpreted broadly. For example, they can refer to a fixed connection or setting, a detachable connection or setting, or an integral connection or setting. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0023] Example 1: Preparation of Tibetan Medicine Composition Formula: 20 kg of sweet osmanthus, 25 kg of raspberry, 18 kg of spruce, and 10 kg of bright salt.

[0024] Preparation process: Pretreatment: The *Mesona chinensis*, *Rosa banksiae*, and *Picea spp.* were cleaned to remove impurities and dried in a 50℃ oven until the moisture content was below 8%. They were then pulverized using a universal pulverizer, passed through a 50-mesh sieve, and mixed evenly to obtain a mixed powder. The *Bright Salt* was pulverized using an ultrafine pulverizer, passed through a 120-mesh sieve, to obtain fine salt powder.

[0025] Ultrasonic extraction: Place the mixed medicinal powder into an ultrasonic extraction vessel, and add 10 times the volume (by weight, 630 kg) of 60% ethanol solution. Turn on stirring and ultrasound, controlling the temperature at 50±2℃ and the ultrasonic power at 400W, and extract for 45 minutes. Filter and collect the first extract. Add 8 times the volume of 60% ethanol solution to the residue again, and perform a second extraction under the same conditions for 30 minutes. Filter and combine the two extracts.

[0026] Concentration: The combined extracts were finely filtered using a plate and frame filter press (equipped with 200-mesh filter cloth). The filtrate was transferred to a double-effect concentrator and concentrated to a thick extract with a relative density of 1.15 at 60°C under vacuum conditions of -0.07 MPa and 60°C.

[0027] Mixing and Drying: The fine salt powder obtained in step 1 is thoroughly mixed with the thick extract in a mixing tank. Then, it is dried using a centrifugal spray drying tower with the inlet air temperature set at 170℃ and the outlet air temperature controlled at 85℃, yielding a light brown powder. Finally, it is passed through a 90-mesh sieve to obtain approximately 15.2 kg of the finished Tibetan medicine composition.

[0028] Example 2: Preparation of Tibetan medicine composition (adjustment of formula ratio) Formula: 15 kg of sweet osmanthus, 30 kg of raspberry, 15 kg of spruce, and 12 kg of bright salt.

[0029] Preparation process: Same as in Example 1.

[0030] Example 3: Preparation of Tibetan medicine composition (process parameter adjustment) Formula: Same as Example 1.

[0031] Adjustments to the preparation process: ethanol concentration was changed to 55%, material-to-liquid ratio was changed to 1:9 (g / mL), ultrasonic temperature was 45℃, power was 350W, extraction time was 50 minutes, and extraction was performed only once. The mixture was concentrated to a relative density of 1.18. Spray drying inlet air temperature was 165℃. The rest was the same as in Example 1.

[0032] Example 4: Preparation of sanitary napkins with added Tibetan medicine composition (core layer addition) Take 50 mg of the Tibetan medicine composition powder prepared in Example 1, and in the core layer forming section of the sanitary napkin production line, use a precision powder spreading device to evenly spread it into the absorbent core layer formed by mixing fluff pulp and superabsorbent polymer (SAP). Then, sequentially laminate the top layer (non-woven fabric) and the bottom layer (PE film), and through processes such as embossing, slicing, and packaging, produce a sanitary napkin containing Tibetan medicine ingredients.

[0033] Example 5: Preparation of sanitary napkins with added Tibetan medicine composition (topcoating) Microcapsule preparation: Take 100g of the Tibetan medicine composition powder prepared in Example 1, mix it with 200g of 10% water-based acrylic binder, add an appropriate amount of deionized water to dilute to a solid content of about 20%, and homogenize it three times under a pressure of 40 MPa using a high-pressure homogenizer to initially form an emulsion.

[0034] Coating: Use a scraper to evenly coat the above-mentioned medicated emulsion onto the back side (i.e. the side in contact with the core layer) of the non-woven fabric (PE / PP composite non-woven fabric) of the sanitary napkin surface layer, with a coating amount of 15g dry weight per square meter of non-woven fabric.

[0035] Drying and Lamination: After drying in 80℃ hot air, it is then laminated with the absorbent core and bottom layer to form a sanitary napkin. This method allows the active ingredients to be closer to the skin, resulting in faster efficacy.

[0036] Comparative Example 1 The composition was prepared using a traditional water extraction method: Following the formulation in Example 1, the mixture was decocted twice with water (10 times the volume of water, 1.5 hours each time), the decoctions were combined, concentrated, mixed with Guangming salt powder, dried, and pulverized. The resulting powder was dark in color, highly hygroscopic, and had poor flowability.

[0037] Experimental Example: In vitro antibacterial effect test 1. Experimental materials: The powder of the composition prepared in Example 1 and Comparative Example 1; Bacterial strains: Staphylococcus aureus (ATCC6538), Escherichia coli (ATCC 8739), and Candida albicans (ATCC 10231).

[0038] 2. Experimental Method: The agar diffusion method (Oxford cup method) was used. The bacterial suspension was prepared and spread onto agar plates. Sterile Oxford cups were placed on these plates, and drug-containing solutions (concentration 100 mg / mL) were added. After incubation at 37℃ for 24 hours, the diameter of the inhibition zone was measured.

[0039] The Tibetan medicine composition prepared in Example 1 of this invention has a significant inhibitory effect on three common pathogenic bacteria, and the effect is significantly better than that of samples prepared by traditional water extraction method, proving that the ultrasonic extraction process used in this invention can more effectively extract antibacterial active ingredients. The above description is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and inventive concept of the present invention, should be covered within the scope of protection of the present invention.

Claims

1. A Tibetan medicine composition for use in sanitary napkins, characterized in that, It is composed of the following components in the indicated mass ratio: 10-30 parts of sweet clover 15-35 parts of bramblewood 10-25 portions of spruce. 5-15 parts of Bright Salt.

2. The Tibetan medicine composition for sanitary napkins according to claim 1, characterized in that, It is composed of the following components in the indicated mass ratio: 15-25 parts of sweet clover 20-30 pieces of bramblewood 15-20 portions of spruce pine 8-12 parts of Bright Salt.

3. The Tibetan medicine composition for sanitary napkins according to claim 1, characterized in that, It is composed of the following components in the indicated mass ratio: 20 portions of sweet clover 25 portions of bramblewood 18 portions of spruce trees. 10 portions of Bright Salt.

4. A method for preparing a Tibetan medicine composition for sanitary napkins, wherein the method is used to prepare the Tibetan medicine composition for sanitary napkins according to any one of claims 1-3, characterized in that, Includes the following steps: S1: Raw material pretreatment: Take the required amounts of Osmanthus fragrans, Rubus idaeus, and Prunus armeniaca, clean and dry them, and then pulverize them through a 40-60 mesh sieve to obtain mixed medicinal powder; pulverize the bright salt separately through a 100-150 mesh sieve to obtain salt powder; S2: Ultrasonic extraction: Mix the mixed medicinal powder with an ethanol solution of 50%-70% concentration at a material-to-liquid ratio of 1:8-1:12 (g / mL), and perform ultrasonic extraction at 40-60℃ with an ultrasonic power of 300-500W and an extraction time of 30-60 minutes, and extract 1-2 times. S3: Concentration: Combine all the extracts from step S2, filter, and concentrate the filtrate under reduced pressure at 50-65℃ and a vacuum degree of -0.06 to -0.08MPa to obtain an extract with a relative density of 1.10-1.20 at 60℃. S4: Mixing and drying: Mix the salt powder obtained in step S1 with the extract obtained in step S3 evenly, and spray dry it. The inlet air temperature is 160-180℃ and the outlet air temperature is 80-90℃ to obtain the powder of the Tibetan medicine composition.

5. The method for preparing a Tibetan medicine composition for sanitary napkins according to claim 4, characterized in that, In step S2, the concentration of the ethanol solution is 60%, the material-to-liquid ratio is 1:10 (g / mL), the ultrasonic temperature is 50℃, the ultrasonic power is 400W, the extraction time is 45 minutes, and the extraction is performed twice.

6. The method for preparing a Tibetan medicine composition for sanitary napkins according to claim 5, characterized in that, In step S4, the powder obtained after spray drying is passed through an 80-100 mesh sieve.

7. The application of a Tibetan medicine composition for sanitary napkins according to any one of claims 1-3, characterized in that, Application in the preparation of sanitary napkins with health-promoting functions.

8. The application of the Tibetan medicine composition for sanitary napkins according to claim 7, characterized in that, The sanitary napkin comprises a top layer, an absorbent core layer, and a bottom layer. The Tibetan medicine composition is evenly sprinkled in the absorbent core layer in powder form, with an addition amount of 10-100 mg per sanitary napkin.

9. The application of the Tibetan medicine composition for sanitary napkins according to claim 7, characterized in that, The Tibetan medicine composition is made into microcapsules using an aqueous adhesive and then coated onto the surface nonwoven fabric of the sanitary napkin.

10. The application of the Tibetan medicine composition for sanitary napkins according to claim 7, characterized in that, Its health benefits include at least one of the following: anti-inflammatory, antibacterial, antimicrobial, relieving menstrual cramps, or improving the environment of the private parts.

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