Intelligent sterile stirring system
By using an intelligent aseptic mixing system, combined with disposable mixing bags and an automated mixing platform, the complexity and contamination risk of aseptic liquid preparation in the field are solved, achieving efficient and reliable aseptic mixing results.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-02-03
- Publication Date
- 2026-03-31
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing technologies make it difficult to achieve sterile liquid preparation in field environments. Traditional mixing equipment is complex to operate, prone to contamination, and lacks the ability to operate in a closed and sterile environment, making it impossible to guarantee sterile quality under complex and variable conditions.
An intelligent aseptic mixing system was designed, which combines a disposable mixing bag and an automated mixing platform. It adopts a self-disinfecting connector, a precision clamping and positioning mechanism and a non-contact drive device, and integrates a control module to achieve fully automated aseptic mixing.
It achieves aseptic, automated and precise liquid mixing operations, improving operational efficiency and system reliability, and ensuring the cleanliness of the sterile environment and the uniformity of mixing.
Smart Images

Figure CN121755097A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the technical field of aseptic mixing, specifically to an intelligent aseptic mixing system. Background Technology
[0002] In emergency rescue, field medical operations, military operations, and remote area work, there is often a need for temporary and rapid preparation of sterile liquids, such as the formulation of medical solutions, on-site production of disinfectants, or immediate preparation of laboratory reagents. These field environments typically lack a stable power supply, complete infrastructure, and a stable clean environment, making traditional stationary mixing equipment unsuitable. The operation process is highly dependent on personnel skills, and microorganisms and airborne contaminants in the environment significantly increase the risk of solution contamination, directly impacting operational efficiency and personnel safety.
[0003] Currently, temporary mixing in field environments often employs manual shaking, magnetic stirring, or simple electric stirring. These methods have significant drawbacks: manual shaking results in poor mixing uniformity, and the opening of containers easily introduces contamination; while portable magnetic stirrers provide stirring power, they struggle to achieve a closed, aseptic operation and have specific requirements regarding container shape; and ordinary electric stirrers compromise the system's airtightness when the stirring rod is inserted into the liquid. Furthermore, existing technologies are generally limited in function, lacking systematic integration of auxiliary functions such as feeding, venting, and temperature maintenance. This results in numerous steps and low efficiency in the entire preparation process, making it difficult to guarantee the aseptic quality of the final product under complex and variable field conditions.
[0004] Therefore, there is an urgent need to develop a highly integrated, easy-to-operate, and mobile solution that can independently complete aseptic mixing tasks in closed environments to meet the specific needs of temporary field applications. Summary of the Invention
[0005] Therefore, the purpose of this invention is to provide an intelligent aseptic stirring system to solve the technical problems mentioned in the background art.
[0006] To achieve the above objectives, the present invention provides the following technical solution: an intelligent aseptic mixing system, comprising a disposable mixing bag and an automated mixing platform. The disposable mixing bag includes a bag body, unfolding components located at the top and bottom of the bag body, a stirrer located at the top of the bag body and extending into the bag body at its lower end, a discharge component located at the bottom of the bag body, a feed pipe and an airflow pipe symmetrically arranged on the outer wall of the bag body and communicating with the bag body, and a sealing component located at the ends of the feed pipe and the airflow pipe. The automated mixing platform includes a base box, a support frame embedded in the base box, a clamping component and a driving component located at the top of the support frame, and two self-disinfecting connectors symmetrically arranged on both sides of the support frame. The support frame supports the bag body through the unfolding components, the driving component drives the stirrer to rotate, one self-disinfecting connector is connected to the airflow control system in the base box through a pipe, and the other self-disinfecting connector is connected to the liquid supply system in the base box through a pipe.
[0007] According to one embodiment of the present invention, the unfolding component includes a horizontal plate disposed at the top of the bag body, upper unfolding plates symmetrically disposed on both sides of the horizontal plate and hinged to the horizontal plate, and two lower arc-shaped unfolding plates symmetrically disposed at the bottom of the bag body and hinged to each other; the bottom of the upper unfolding plate is connected to the top of the bag body, and the top of the lower arc-shaped unfolding plate is connected to the bottom of the bag body. In this preferred embodiment, the unfolding component enables the bag body to unfold.
[0008] According to one embodiment of the present invention, the stirrer includes a rotating disk passing through and rotatably connected to the horizontal plate, a drive disk disposed at the top of the rotating disk, and a stirring rod disposed at the bottom of the rotating disk and arranged at an incline; the end of the stirring rod is provided with a spoon portion. In this preferred embodiment, the stirrer facilitates the stirring of the mixture inside the bag.
[0009] According to one embodiment of the present invention, the sealing component includes a sealing box with one end connected to the feed pipe, a conveying hole horizontally inserted through the sealing box and connected to the feed pipe, a vertical gate plate with one end slidably connected to the inner wall of the sealing box and the other end extending to the outside of the sealing box, and a plurality of springs disposed inside the sealing box for supporting the vertical gate plate. In this preferred embodiment, the sealing component facilitates self-sealing of the air inlet and raw material inlet of the bag.
[0010] According to one embodiment of the present invention, the unloading component includes an unloading pipe with its top communicating with the bottom of the bag, a sealing cap with its inner wall threadedly connected to the outer wall of the unloading pipe, and a sealing post with its bottom connected to the sealing cap and its top extending to the top of the inner wall of the unloading pipe. In this preferred embodiment, the unloading component facilitates the discharge of the mixture from the bag.
[0011] According to one embodiment of the present invention, a temperature regulating component is further provided at the bottom of the bag body. The temperature regulating component includes a first arc-shaped heat-conducting sheet at the bottom of each of the lower arc-shaped display plates, two second arc-shaped heat-conducting sheets symmetrically disposed at the bottom of the bag body, a plurality of heat-conducting pillars disposed between the first and second arc-shaped heat-conducting sheets at corresponding positions, and a heater embedded in the outer wall of the support frame and corresponding to the position of the first arc-shaped heat-conducting sheet. In this preferred embodiment, the temperature regulating component facilitates the adjustment of the raw material temperature during stirring and mixing.
[0012] According to one embodiment of the present invention, the clamping component includes two guide grooves symmetrically arranged at the bottom of the support frame, two horizontal guide plates symmetrically arranged on both sides of the support frame, an electric cylinder disposed at the top of the support frame, and a Z-shaped pressure plate disposed at the actuating end of the electric cylinder. In this preferred embodiment, the clamping component facilitates the stable fixing of the bag.
[0013] According to one embodiment of the present invention, the driving component includes a base box disposed at the bottom of the support frame, a drive motor disposed within the base box and having its actuating end passing through the base box, and a drive turntable disposed at the actuating end of the drive motor. In this preferred embodiment, the driving component facilitates the rotation of the stirrer for stirring processing.
[0014] According to one embodiment of the present invention, the self-cleaning connector includes an unsealing box disposed at the bottom of the base box, an unlocking vertical plate disposed within the unsealing box, a communicating hole passing through the unlocking vertical plate, and a delivery pipe having one end connected to the unsealing box. In this preferred embodiment, the self-cleaning connector facilitates connection with the sealing component and removes the sealing effect of the sealing component.
[0015] According to one embodiment of the present invention, a sterile connection auxiliary component is further provided at the bottom of the unsealing box. The sterile connection auxiliary component includes an extension cover provided at the bottom of the unsealing box and communicating with the unsealing box, a spray ring provided on the outer wall of the extension cover, a disinfectant pipe with one end connected to the spray ring, and an infrared sensor provided at the bottom of the extension cover; the spray nozzle of the spray ring is connected to the extension cover. In this preferred embodiment, the sterile connection auxiliary component facilitates sterile processing during the connection of the sealing component and the self-disinfecting connector.
[0016] In summary, the present invention has the following main beneficial effects: The intelligent aseptic mixing system of this invention achieves aseptic, automated, and precise operation of the liquid mixing process through the innovative combination of disposable mixing bags and an automated mixing platform. It provides an efficient and reliable solution for fields requiring a sterile environment, such as pharmaceuticals and bioengineering.
[0017] The disposable mixing bag integrates an expandable bag body, a built-in mixer, a sealed discharge component, and inlet / outlet pipes with self-sealing function. It is lightweight and designed for single use, fundamentally avoiding the risk of cross-contamination. The automated mixing platform is equipped with a precision clamping and positioning mechanism, a non-contact drive device, and a connection interface with self-disinfection function. A central controller enables fully automated control of the mixing process. Users simply unfold the mixing bag, install and fix it, and automatically dock it with the platform to start the complete mixing process, significantly improving operational efficiency and system reliability.
[0018] Regarding aseptic protection, the self-disinfecting connector employs an infrared sensor-triggered disinfection mechanism, automatically spraying disinfectant the moment the pipes are connected, ensuring a sterile connection process. Its unique sealing design keeps the pipes completely sealed when not connected, opening only after successful connection. Combined with disposable bag material, this creates a closed, aseptic operating environment, effectively guaranteeing the cleanliness requirements of the materials throughout the entire mixing process.
[0019] The system's intelligence is most prominently reflected in its integrated control modules. The central controller manages multiple functional modules, including clamping and fixing, mixing, liquid delivery, air pressure regulation, temperature control, and sterilization. The drive system uses friction transmission to power a specially designed tilting stirring rod, achieving efficient and uniform mixing. The air pressure control system automatically adjusts the pressure inside the bag to ensure full bag expansion. The temperature regulation module uses heat-conducting elements to uniformly heat the materials, meeting the special process requirements of temperature-sensitive materials. The liquid supply system ensures accurate ingredient ratios through precise flow control. Attached Figure Description
[0020] Figure 1 This is an isometric view of the overall structure of the stirring system of the present invention; Figure 2 This is an exploded view of the overall structure of the stirring system of the present invention; Figure 3 This is an exploded view of the disposable mixing bag structure of the present invention; Figure 4 This is an exploded view of the sealing component structure of the present invention; Figure 5 This is an exploded view of the automated mixing platform structure of the present invention; Figure 6 This is an exploded view of the clamping component structure of the present invention; Figure 7 This is an exploded view of the aseptic connection auxiliary component structure of the present invention; Figure 8 This is a cross-sectional view of the disposable mixing bag structure of the present invention; Figure 9 This is the overall structure of the stirring system of the present invention; Figure 10 For the present invention Figure 8 Enlarged view of the structure at point A in the image; Figure 11 This is a system structure framework diagram of the present invention; Figure 12 This is a structural framework diagram of the controller system of the present invention.
[0021] Figure Descriptions: 10. Disposable mixing bag; 11. Bag body; 111. Feed pipe; 112. Airflow pipe; 12. Unfolding component; 121. Horizontal plate; 122. Upper unfolding plate; 123. Lower arc-shaped unfolding plate; 13. Stirrer; 131. Rotating disc; 132. Drive disc; 133. Stirring rod; 1331. Spoon; 14. Discharge component; 141. Discharge pipe; 142. Sealing cap; 143. Sealing column; 15. Sealing component; 151. Spring; 152. Sealing box; 153. Conveying hole; 154. Vertical gate plate; 16. Temperature regulating component; 161. First arc-shaped heat-conducting plate; 162. Second arc-shaped heat-conducting plate. 163. Heat-conducting column; 164. Heater; 20. Automated mixing platform; 21. Base box; 22. Support frame; 23. Clamping component; 231. Guide groove; 232. Horizontal guide plate; 233. Electric cylinder; 234. Z-shaped pressure plate; 24. Drive component; 241. Base box; 242. Drive motor; 243. Drive turntable; 25. Self-disinfecting connector; 251. Unsealing box; 252. Unlocking vertical plate; 253. Connecting hole; 254. Delivery pipe; 255. Aseptic connection auxiliary component; 2551. Extension cover; 2552. Spray ring; 2553. Disinfectant pipe; 2554. Infrared sensor. Detailed Implementation
[0022] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.
[0023] The embodiments of the present invention will now be described.
[0024] Please refer to the appendix for details. Figure 1 , 2As shown in Figures 3, 4, and 8, in a preferred embodiment of the present invention, an intelligent aseptic mixing system includes a disposable mixing bag 10 and an automated mixing platform 20. The disposable mixing bag 10 includes a bag body 11, unfolding components 12 disposed at the top and bottom of the bag body 11, a stirrer 13 disposed at the top of the bag body 11 and extending to the bottom of the bag body 11, a discharge component 14 disposed at the bottom of the bag body 11, a feed pipe 111 symmetrically disposed on the outer wall of the bag body 11 and communicating with the bag body 11, and an air... The bag body 11 includes a flow pipe 112 and a sealing component 15 located at the ends of the feed pipe 111 and the airflow pipe 112. The unfolding component 12 includes a horizontal plate 121 located at the top of the bag body 11, an upper unfolding plate 122 symmetrically arranged on both sides of the horizontal plate 121 and hinged to the horizontal plate 121, and two lower arc-shaped unfolding plates 123 symmetrically arranged at the bottom of the bag body 11 and hinged to each other. The bottom of the upper unfolding plate 122 is connected to the top of the bag body 11, and the top of the lower arc-shaped unfolding plate 123 is connected to the bottom of the bag body 11. The agitator 13 is connected to the horizontal plate 121, and includes a rotating disk 131 that passes through and is rotatably connected to the horizontal plate 121, a drive disk 132 located at the top of the rotating disk 131, and an inclined stirring rod 133 located at the bottom of the rotating disk 131; the stirring rod 133 has a spoon portion 1331 at its end. The sealing component 15 includes a sealing box 152 with one end connected to the feed pipe 111, and a conveying device that passes horizontally through the sealing box 152 and is connected to the feed pipe 111. The device includes a hole 153, a vertical gate 154 that is slidably connected at one end to the inner wall of the sealing box 152 and extends to the outside of the sealing box 152 at the other end, and a plurality of springs 151 disposed inside the sealing box 152 for supporting the vertical gate 154. The unloading component 14 includes an unloading pipe 141 whose top is connected to the bottom of the bag body 11, a sealing cap 142 whose inner wall is threaded to the outer wall of the unloading pipe 141, and a sealing post 143 whose bottom is connected to the sealing cap 142 and whose top extends to the top of the inner wall of the unloading pipe 141.
[0025] It should be noted that in this embodiment, disposable containers have a great advantage when preparing temporary aseptic liquids. The aseptic stirring system in this invention uses disposable containers for stirring, which is convenient to carry and aseptic, easy to mix, and easy to transport the finished product. In use, the operator takes out a disposable mixing bag 10 from the sealed bag and unfolds it through the unfolding component 12. The unfolded disposable mixing bag 10 is placed on the support frame 22. Under the premise that the actuator end of the drive component 24 contacts the stirrer 13, the disposable mixing bag 10 is fixed by the clamping component 23. After the disposable mixing bag 10 is fixed, the sealing component 15 corresponding to the feed pipe 111 is connected to the self-disinfection connector 25 corresponding to the liquid supply system, and the sealing component 15 corresponding to the airflow pipe 112 is connected to the self-disinfection connector 25 corresponding to the airflow control system. After connection, the liquid supply system supplies raw material liquid to the disposable mixing bag 10 through the pipeline. The airflow control system adjusts the air pressure inside the disposable mixing bag 10 to ensure that the disposable mixing bag 10 is fully expanded. The drive component 24 drives the stirrer 13 to fully stir the raw material liquid to achieve liquid preparation and mixing. After mixing is complete, clamping component 23 is released, and sealing component 15 and self-disinfection connector 25 are manually separated to remove disposable mixing bag 10. When unloading is required, unloading component 14 is opened to use the liquid in disposable mixing bag 10. Furthermore, when the unfolding component 12 is in use, the upper display plate 122 and the lower arc-shaped display plate 123 are moved to keep the upper display plate 122 and the horizontal plate 121 on the same horizontal plane, and to keep the two lower arc-shaped display plates 123 on the same horizontal plane, so as to complete the unfolding. When the disposable mixing bag 10 is placed on the support frame 22, the outer edge of the lower arc-shaped display plate 123 is placed in the guide groove 231. The outer edge of the upper display plate 122 is placed on the horizontal guide plate 232. Furthermore, when the stirrer 13 is in use, the drive motor 242 drives the drive disk 132 to rotate, the drive disk 132 drives the rotating disk 131 and the stirring rod 133 to rotate, and the stirring rod 133 and the spoon 1331 stir and mix the liquid. Furthermore, when the unloading component 14 is in use, the sealing column 143 seals the unloading pipe 141 to ensure the sealing of the unloading pipe 141 and prevent the liquid in the bag body 11 from being unevenly stirred due to the liquid in the unloading pipe 141. When unloading, simply unscrew the sealing cap 142. Furthermore, when the sealing component 15 is in use, the spring 151 supports the vertical gate 154, and the vertical gate 154 seals the conveying hole 153.
[0026] Please refer to the appendix for details. Figure 5 , 6As shown in Figure 9, in another preferred embodiment of the present invention, the automated mixing platform 20 includes a base box 21, a support frame 22 embedded in the base box 21, a clamping component 23 and a driving component 24 disposed on the top of the support frame 22, and two self-disinfecting connectors 25 symmetrically disposed on both sides of the support frame 22; the clamping component 23 includes two guide grooves 231 symmetrically disposed on the bottom of the support frame 22, two horizontal guide plates 232 symmetrically disposed on both sides of the support frame 22, an electric cylinder 233 disposed on the top of the support frame 22, and a Z-shaped pressure plate 234 disposed on the execution end of the electric cylinder 233; the driving component 24 includes a base box 241 disposed on the bottom of the support frame 22, a driving motor 242 disposed in the base box 241 and whose execution end passes through the base box 241, and a driving turntable 243 disposed on the execution end of the driving motor 242.
[0027] It should be noted that, in this embodiment, when the clamping component 23 is working, the actuator of the electric cylinder 233 drives the U-shaped pressure plate 234 to descend, and the U-shaped pressure plate 234 cooperates with the horizontal guide plate 232 to achieve clamping; Furthermore, when the drive component 24 is working, the drive motor 242 drives the drive turntable 243 to rotate, and the drive turntable 243 drives the drive disk 132 in contact to rotate through friction.
[0028] Please refer to the appendix for details. Figure 3 , 7As shown in Figures 8, 10, 11, and 12, in another preferred embodiment of the present invention, the support frame 22 carries the bag body 11 through the unfolded component 12, the driving component 24 is used to drive the stirrer 13 to rotate, one self-disinfecting connector 25 is connected to the airflow control system in the base box 21 through a pipe, and the other self-disinfecting connector 25 is connected to the liquid supply system in the base box 21 through a pipe. It also includes a temperature regulating component 16 located at the bottom of the bag body 11. The temperature regulating component 16 includes a first arc-shaped heat-conducting sheet 161 located at the bottom of each of the lower arc-shaped display plates 123, two second arc-shaped heat-conducting sheets 162 symmetrically located at the bottom of the bag body 11, a plurality of heat-conducting columns 163 located between the first and second arc-shaped heat-conducting sheets 161 at corresponding positions, and a plurality of heat-conducting columns 163 embedded in the outer wall of the support frame 22 and connected to the first… The heater 164 is located at the position of the arc-shaped heat-conducting plate 161. The self-disinfecting connector 25 includes an unsealing box 251 located at the bottom of the base box 241, an unlocking vertical plate 252 located inside the unsealing box 251, a connecting hole 253 passing through the unlocking vertical plate 252, and a delivery pipe 254 connected to the unsealing box 251 at one end. It also includes a sterile connection auxiliary component 255 located at the bottom of the unsealing box 251. The sterile connection auxiliary component 255 includes an extension cover 2551 located at the bottom of the unsealing box 251 and connected to the unsealing box 251, a spray ring 2552 located on the outer wall of the extension cover 2551, a disinfectant pipe 2553 connected to the spray ring 2552 at one end, and an infrared sensor 2554 located at the bottom of the extension cover 2551. The spray nozzle of the spray ring 2552 is connected to the extension cover 2551.
[0029] It should be noted that in this embodiment, the automated mixing platform 20 is connected to the controller, which can be connected to a mobile client via a network. The controller includes a fixing module, a mixing module, a liquid supply module, a gas supply module, a heating module, and a sterile module. The fixing module is used to trigger the clamping component 23 to clamp the disposable mixing bag 10; The stirring module is used to trigger the drive component 24 to drive the stirrer 13 to perform stirring operations; The liquid supply module is used to trigger the liquid supply system in the base box 21 to supply raw material liquid to the disposable mixing bag 10; The gas supply module is used to trigger the airflow control system in the base box 21 to regulate the gas pressure in the disposable mixing bag 10; The heating module is used to trigger the heater 164 to heat the liquid inside the disposable mixing bag 10; The aseptic module is used to receive obstacle information measured by the infrared sensor 2554, and triggers the aseptic connection auxiliary component 255 to perform sterilization operation when acquiring obstacle information; Furthermore, when the sealing component 15 is connected to the self-disinfection connector 25, the sealing box 152 is inserted into the unsealing box 251 and engages with the unsealing box 251. During this process, the unlocking vertical plate 252 pushes down the vertical gate 154, and the delivery hole 153 connects with the connecting hole 253 to complete the sealing release. Furthermore, when the aseptic connection auxiliary component 255 is working, during the process of the sealing box 152 being inserted into the unsealing box 251, the aseptic module is used to receive obstacle information measured by the infrared sensor 2554, and when the obstacle information is acquired, it triggers the disinfectant supply system in the base box 21 to supply disinfectant. The disinfectant is sprayed out after passing through the disinfectant pipe 2553 and the spray ring 2552 to sterilize the sealing box 152 that is about to be connected to the unsealing box 251. The disinfectant supply system includes a miniature delivery pump and a disinfectant storage tank installed in the base box 21. The input end of the miniature delivery pump is connected to the disinfectant storage tank through a pipeline. The input end of the miniature delivery pump is connected to the disinfectant pipe 2553. The disinfectant can be supplied by opening the electric control valve on the disinfectant storage tank and the miniature delivery pump. Furthermore, when the temperature regulating component 16 is working, the heating module receives the temperature information of the disposable stirring bag 10 measured by the temperature sensor set on the support frame 22, and after analysis, triggers the heater 164 to heat. When the heater 164 heats, the heat energy is transferred to the mixture through thermal radiation via the first arc-shaped heat-conducting plate 161, the heat-conducting column 163 and the second arc-shaped heat-conducting plate 162. Furthermore, the airflow control system includes an electric valve located in the base box 21, an exhaust pipe connected to one end of the electric valve and a micro air pump via a pipe, and the other end of the electric valve connected to one of the self-disinfection connectors 25 via a first air pipe. A pressure sensor can be installed on the first air pipe. The gas supply module receives the pressure information measured by the pressure sensor and triggers the electric valve and the micro air pump after analysis. When the electric valve is connected to the miniature air pump and the first air pipe, it can increase the pressure; when the electric valve is connected to the first air pipe and the exhaust pipe, it can decrease the pressure. Furthermore, the liquid supply system includes a miniature delivery pump and multiple liquid storage tanks located in the base box 21. The input end of the miniature delivery pump is connected to the multiple liquid storage tanks through a pipe, and the output end is connected to another self-disinfecting connector 25 through a liquid delivery pipe. A flow sensor can be installed on the liquid delivery pipe to monitor the flow rate. The liquid supply module can trigger the valve on the corresponding liquid storage tank to open and trigger the miniature delivery pump to start according to the setting information, thereby supplying liquid.
[0030] The working principle of this invention is as follows: In use, the operator takes out a disposable mixing bag 10 from the sealed bag and unfolds it through the unfolding component 12. The unfolded disposable mixing bag 10 is placed on the support frame 22. Under the premise that the actuator end of the drive component 24 contacts the stirrer 13, the disposable mixing bag 10 is fixed by the clamping component 23. After the disposable mixing bag 10 is fixed, the sealing component 15 corresponding to the feed pipe 111 is connected to the self-disinfection connector 25 corresponding to the liquid supply system, and the sealing component 15 corresponding to the airflow pipe 112 is connected to the self-disinfection connector 25 corresponding to the airflow control system. After connection, the liquid supply system supplies raw material liquid to the disposable mixing bag 10 through the pipeline. The airflow control system adjusts the air pressure inside the disposable mixing bag 10 to ensure that the disposable mixing bag 10 is fully expanded. The drive component 24 drives the stirrer 13 to fully stir the raw material liquid to achieve liquid preparation and mixing. After mixing is complete, clamping component 23 is released, and sealing component 15 and self-disinfection connector 25 are manually separated to remove disposable mixing bag 10. When unloading is required, unloading component 14 is opened to use the liquid in disposable mixing bag 10. When the unfolding component 12 is in use, the upper display plate 122 and the lower arc-shaped display plate 123 are moved to keep the upper display plate 122 and the horizontal plate 121 on the same horizontal plane, and to keep the two lower arc-shaped display plates 123 on the same horizontal plane to complete the unfolding. When the disposable mixing bag 10 is placed on the support frame 22, the outer edge of the lower arc-shaped display plate 123 is placed in the guide groove 231. The outer edge of the upper display plate 122 is placed on the horizontal guide plate 232. When the stirrer 13 is in use, the drive motor 242 drives the drive disk 132 to rotate, the drive disk 132 drives the rotating disk 131 and the stirring rod 133 to rotate, and the stirring rod 133 and the spoon 1331 stir and mix the liquid. When the unloading component 14 is in use, the sealing column 143 seals the unloading pipe 141 to ensure the sealing of the unloading pipe 141 and prevent the liquid in the bag 11 from being unevenly stirred due to the liquid in the unloading pipe 141. When unloading, simply unscrew the sealing cap 142. When the blocking component 15 is in use, the spring 151 supports the vertical gate 154, and the vertical gate 154 blocks the conveying hole 153; The automated mixing platform 20 is connected to the controller, which can be connected to a mobile client via the network. The controller includes a fixing module, a mixing module, a liquid supply module, a gas supply module, a heating module, and a sterile module. The fixing module is used to trigger the clamping component 23 to clamp the disposable mixing bag 10; The stirring module is used to trigger the drive component 24 to drive the stirrer 13 to perform stirring operations; The liquid supply module is used to trigger the liquid supply system in the base box 21 to supply raw material liquid to the disposable mixing bag 10; The gas supply module is used to trigger the airflow control system in the base box 21 to regulate the gas pressure in the disposable mixing bag 10; The heating module is used to trigger the heater 164 to heat the liquid inside the disposable mixing bag 10; The aseptic module is used to receive obstacle information measured by the infrared sensor 2554, and triggers the aseptic connection auxiliary component 255 to perform sterilization operation when acquiring obstacle information; When the sealing component 15 is connected to the self-disinfection connector 25, the sealing box 152 is inserted into the unsealing box 251 and engages with the unsealing box 251. During this process, the unlocking vertical plate 252 pushes down the vertical gate 154, and the delivery hole 153 connects with the connecting hole 253 to complete the sealing release. When the aseptic connection auxiliary component 255 is working, during the process of the sealing box 152 being inserted into the unsealing box 251, the aseptic module is used to receive obstacle information measured by the infrared sensor 2554, and when the obstacle information is acquired, it triggers the disinfectant supply system in the base box 21 to supply disinfectant. The disinfectant is sprayed out after passing through the disinfectant pipe 2553 and the spray ring 2552 to sterilize the sealing box 152 that is about to be connected to the unsealing box 251. The disinfectant supply system includes a miniature delivery pump and a disinfectant storage tank installed in the base box 21. The input end of the miniature delivery pump is connected to the disinfectant storage tank through a pipeline. The input end of the miniature delivery pump is connected to the disinfectant pipe 2553. The disinfectant can be supplied by opening the electric control valve on the disinfectant storage tank and the miniature delivery pump. When the temperature regulating component 16 is working, the heating module receives the temperature information of the disposable stirring bag 10 measured by the temperature sensor set on the support frame 22, and after analysis, triggers the heater 164 to heat. When the heater 164 heats, the heat energy is transferred to the mixture through thermal radiation via the first arc-shaped heat-conducting plate 161, the heat-conducting column 163 and the second arc-shaped heat-conducting plate 162. The airflow control system includes an electric valve located in the base box 21, an exhaust pipe connected to one end of the electric valve and a micro air pump via a pipe, and the other end of the electric valve connected to one of the self-disinfection connectors 25 via a first air pipe. A pressure sensor can be installed on the first air pipe. The gas supply module receives the pressure information measured by the pressure sensor and triggers the electric valve and the micro air pump after analysis. When the electric valve is connected to the miniature air pump and the first air pipe, it can increase the pressure; when the electric valve is connected to the first air pipe and the exhaust pipe, it can decrease the pressure. The liquid supply system includes a miniature delivery pump and multiple liquid storage tanks located in the base box 21. The input end of the miniature delivery pump is connected to the multiple liquid storage tanks through a pipe, and the output end is connected to another self-disinfecting connector 25 through a liquid delivery pipe. A flow sensor can be installed on the liquid delivery pipe to monitor the flow rate. The liquid supply module can trigger the valve on the corresponding liquid storage tank to open and trigger the miniature delivery pump to start according to the setting information, so as to supply liquid. When the clamping component 23 is working, the actuator of the electric cylinder 233 drives the Z-shaped pressure plate 234 to descend. The Z-shaped pressure plate 234 cooperates with the horizontal guide plate 232 to achieve clamping. When the drive component 24 is working, the drive motor 242 drives the drive turntable 243 to rotate, and the drive turntable 243 drives the drive disk 132 in contact to rotate through friction.
[0031] Although embodiments of the present invention have been shown and described, these specific embodiments are merely explanations of the invention and are not intended to limit it. The specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. After reading this specification, those skilled in the art may make modifications, substitutions, and variations to the embodiments as needed without departing from the principles and spirit of the invention, but such modifications, substitutions, and variations are protected by patent law as long as they are within the scope of the claims of the present invention.
Claims
1. An intelligent aseptic mixing system comprising a disposable mixing bag (10) and an automated mixing platform (20), characterized in that, The disposable stirring bag (10) comprises a bag body (11), unfolding components (12) arranged at the top and bottom of the bag body (11), a stirrer (13) arranged at the top of the bag body (11) and extending into the bag body (11), a discharging component (14) arranged at the bottom of the bag body (11), a feeding pipe (111) and an airflow pipe (112) symmetrically arranged on the outer wall of the bag body (11) and communicating with the bag body (11), and a blocking component (15) arranged at the end of the feeding pipe (111) and the airflow pipe (112). The automatic stirring platform (20) comprises a base box (21), a bearing frame (22) embedded in the base box (21), clamping components (23) and driving components (24) arranged at the top of the bearing frame (22), and two self-sterilization connectors (25) symmetrically arranged on both sides of the bearing frame (22). The bearing frame (22) bears the bag body (11) through the unfolded unfolding components (12), the driving components (24) are used for driving the stirrer (13) to rotate, one of the self-sterilization connectors (25) is connected with an airflow control system in the base box (21) through a pipeline, and the other self-sterilization connector (25) is connected with a liquid supply system in the base box (21) through a pipeline.
2. The intelligent aseptic mixing system according to claim 1, wherein, The unfolding components (12) comprise a horizontal plate (121) arranged at the top of the bag body (11), upper unfolding plates (122) symmetrically arranged on both sides of the horizontal plate (121) and hinged to the horizontal plate (121), and two lower arc-shaped unfolding plates (123) symmetrically arranged at the bottom of the bag body (11) and hinged to each other. The bottom of the upper unfolding plate (122) is connected with the top of the bag body (11), and the top of the lower arc-shaped unfolding plate (123) is connected with the bottom of the bag body (11).
3. The intelligent aseptic mixing system according to claim 2, wherein, The stirrer (13) comprises a rotating disc (131) penetrating through the horizontal plate (121) and rotationally connected with the horizontal plate (121), a driving disc (132) arranged at the top of the rotating disc (131), and a stirring rod (133) arranged at the bottom of the rotating disc (131) and inclined. A spoon part (1331) is arranged at the end of the stirring rod (133).
4. The intelligent aseptic mixing system according to claim 1, wherein, The blocking component (15) comprises a blocking box (152) communicating with the feeding pipe (111) at one end, a conveying hole (153) horizontally penetrating through the blocking box (152) and communicating with the feeding pipe (111), a vertical gate plate (154) slidingly connected with the inner wall of the blocking box (152) at one end and extending to the outside of the blocking box (152) at the other end, and a plurality of springs (151) arranged in the blocking box (152) and used for supporting the vertical gate plate (154).
5. The intelligent sterile mixing system according to claim 1, wherein, The discharging component (14) comprises a discharging pipe (141) communicating with the bottom of the bag body (11) at the top, a sealing cover (142) threadedly connected with the outer wall of the discharging pipe (141), and a blocking column (143) connected with the sealing cover (142) at the bottom and extending to the top of the inner wall of the discharging pipe (141).
6. The intelligent aseptic mixing system according to claim 2, wherein, Further comprising a temperature adjusting component (16) arranged at the bottom of the bag body (11), the temperature adjusting component (16) comprising a first arc-shaped heat conduction sheet (161) arranged at the bottom of each of the lower arc-shaped panels (123), two second arc-shaped heat conduction sheets (162) symmetrically arranged at the bottom of the bag body (11), and a plurality of heat conduction columns (163) arranged between the first arc-shaped heat conduction sheet (161) and the second arc-shaped heat conduction sheet (162) at corresponding positions; and a heater (164) embedded in the outer wall of the bearing frame (22) and corresponding to the position of the first arc-shaped heat conduction sheet (161).
7. The intelligent sterile mixing system according to claim 1, wherein, The clamping component (23) comprises two guide grooves (231) symmetrically arranged at the bottom of the bearing frame (22), two horizontal guide plates (232) symmetrically arranged at the two sides of the bearing frame (22), an electric cylinder (233) arranged at the top of the bearing frame (22), and a few-shaped pressing plate (234) arranged at the execution end of the electric cylinder (233).
8. The intelligent sterile mixing system according to claim 1, wherein, The driving component (24) comprises a base box (241) arranged at the bottom of the bearing frame (22), a driving motor (242) arranged in the base box (241) and penetrating through the base box (241) at the execution end, and a driving turntable (243) arranged at the execution end of the driving motor (242).
9. The intelligent aseptic mixing system according to claim 8, wherein, The self-sterilizing connector (25) comprises an unsealing box (251) arranged at the bottom of the base box (241), an unlocking vertical plate (252) arranged in the unsealing box (251), a communication hole (253) penetrating through the unlocking vertical plate (252), and a delivery pipe (254) communicating with one end of the unsealing box (251).
10. The intelligent aseptic mixing system according to claim 9, wherein, Further comprising a sterile connection auxiliary assembly (255) arranged at the bottom of the unsealing box (251), the sterile connection auxiliary assembly (255) comprising an extension cover (2551) arranged at the bottom of the unsealing box (251) and communicating with the unsealing box (251), a liquid spraying ring (2552) arranged on the outer wall of the extension cover (2551), a sterilization liquid pipe (2553) communicating with one end of the liquid spraying ring (2552), and an infrared sensor (2554) arranged at the bottom of the extension cover (2551); The liquid spraying ring (2552) communicates with the extension cover (2551).