Multifunctional myocardial in-situ injection device and system

Abstract

The invention relates to a multifunctional myocardial in-situ injection device and system. The multifunctional myocardial in-situ injection device comprises a holding unit, a catheter unit, a rotating unit, a first bending adjusting unit, a second bending adjusting unit, a main electrode unit, at least one auxiliary electrode unit, a limiting unit and a telescopic injection unit. The catheter has the advantages that the first bending adjusting unit and the second bending adjusting unit can be used for adjusting the relative bending degree of the bent pipe section of the catheter unit so as to be better suitable for the structure of the myocardial part; the electric potential between the main electrode unit and the auxiliary electrode unit can be used for mapping the myocardial part where the first end of the catheter unit is located and judging whether the telescopic injection unit is tightly attached to the heart or not, so that the structure is further suitable for the myocardial part; the telescopic injection unit can be used for carrying out auxiliary propelling operation on the injection needle, so that the phenomenon of unstable manual propelling is avoided, and the injection stability is improved; and an injection hose of the telescopic injection unit can be stabilized by utilizing the limiting unit, so that the stability is further improved.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a multifunctional myocardial in situ injection device and system. Background Technology

[0002] With advancements in medicine, gene therapy and cell therapy have experienced rapid development. Various cardiomyopathy diseases, such as ischemic cardiomyopathy, are common illnesses that seriously threaten human health, and current conventional treatments have limited efficacy. Gene therapy, nucleic acid therapy, cytokine infusion, and cell therapy for cardiovascular-related diseases are increasingly being researched and applied clinically, demonstrating enormous potential. However, a key aspect is the homing, settlement, proliferation, and local aggregation of cells, factors, and drugs to the myocardium requiring repair, ultimately integrating with host cardiomyocytes to achieve functional coordination and therapeutic effects. Current drug delivery routes primarily involve intracoronary or subcutaneous administration via microcatheters or balloons into the coronary arteries. A problem with this method is that, despite intracoronary administration, the drug can rapidly disseminate to peripheral tissues due to blood flow, affecting its effectiveness. Finding new drug delivery routes is crucial for improving treatment outcomes.

[0003] Oral myocardial injection is a viable and effective alternative. Oral myocardial injection can be performed under direct surgical visualization or via catheter-guided subendocardial injection. Direct surgical visualization is highly invasive and only suitable for patients undergoing surgery. Subendocardial injection via catheter-guided injection is less invasive and repeatable. However, endocardial injection has not yet been widely adopted because there is currently no inexpensive, readily available, easily operable, and precisely targeted endocardial injection catheter.

[0004] The main components of DSA-guided subendocardial in situ injection consist of a catheter and a syringe. Currently, the catheter (Swartz septal puncture) is commonly used. However, the Swartz catheter is specifically designed for catheter ablation of atrioventricular bypass tracts and is not suitable for in situ myocardial injection performed within the ventricle. The Swartz catheter includes a metal mesh structure with a certain degree of flexibility. It can be manually bent to suit different tissue locations, but this bending method has low precision. Given the complex structure of the myocardium, it is difficult to fit the syringe to the target area, leading to ineffective injections. To adapt to the structure of the myocardium, the Swartz catheter sometimes needs to be bent multiple times, but this method prolongs the procedure time and has poor stability during injection, resulting in limited practicality.

[0005] Currently, no effective solutions have been proposed for the problems of low syringe adjustment accuracy, ineffective injection, and poor stability in related technologies. Summary of the Invention

[0006] The purpose of this invention is to address the shortcomings of existing technologies by providing a multifunctional myocardial in situ injection device and system, thereby solving the problems of low syringe adjustment accuracy, ineffective injection, and poor stability in related technologies.

[0007] To achieve the above objectives, the technical solution adopted by the present invention is as follows:

[0008] In a first aspect, the present invention provides a multifunctional in situ myocardial injection device, comprising:

[0009] A grip unit for use by a user;

[0010] The catheter unit includes a curved section and a straight section, the second end of the curved section is connected to the first end of the straight section, and the second end of the straight section of the catheter unit is connected to the first end of the holding unit.

[0011] A rotating unit, which is rotatably disposed inside the gripping unit;

[0012] A first bending adjustment unit, wherein a first end of the first bending adjustment unit is connected to a second end of the curved section of the catheter unit, and the second end of the first bending adjustment unit is slidably connected to the gripping unit, for driving the curved section of the catheter unit to bend in a first direction;

[0013] The second bending adjustment unit has a first end connected to the second end of the curved section of the catheter unit, and the second end of the second bending adjustment unit bypasses the rotating unit and is slidably connected to the holding unit, for driving the curved section of the catheter unit to bend in a second direction, wherein the second direction is opposite to the first direction;

[0014] The main electrode unit has a first end connected to the first end of the curved section of the catheter unit, and a second end passing through the catheter unit and the holding unit and connected to the three-dimensional positioning device. It is used to determine whether the first end of the curved section of the catheter unit is in close contact with the myocardium based on whether a damage current appears in the monopolar mapping and to send data to the remote control system.

[0015] At least one auxiliary electrode unit, the first end of which is connected to the first end of the curved section of the catheter unit, and the second end of which passes through the catheter unit and the holding unit and is connected to the three-dimensional positioning device, for use in conjunction with the main electrode unit to map the position of the myocardium and send data to the remote control system;

[0016] A limiting unit is disposed at the top of the gripping unit and communicates with the gripping unit;

[0017] A telescopic injection unit, wherein the first end of the telescopic injection unit is internally connected to the first end of the curved section of the catheter unit, and the second end of the telescopic injection unit passes through the catheter unit, the gripping unit, and the limiting unit and communicates with the liquid supply device, and abuts against the limiting unit, for in situ injection of myocardium and fixation under the action of the limiting unit.

[0018] In some embodiments, the gripping unit includes:

[0019] A gripping element, the first end of which is connected to the second end of the straight tube section of the conduit unit, the top end of which is connected to the bottom end of the limiting unit, and the interior of which is rotatably connected to the rotating unit for use by the user;

[0020] A first receiving element is disposed at the top of the gripping element and communicates with the limiting unit for the telescopic injection unit to pass through the gripping element;

[0021] A first sliding element is disposed at the front end of the gripping element and is slidably connected to the first bending adjustment unit and the second bending adjustment unit, respectively;

[0022] A first injection hole element is disposed at a first end of the gripping element and communicates with the catheter unit for the telescopic injection unit to pass through the gripping element.

[0023] Two auxiliary electrode hole elements are respectively disposed at the first end and the second end of the gripping element, and are located above the first sliding element and communicate with the conduit unit for the auxiliary electrode unit to pass through the gripping element;

[0024] Two main electrode hole elements are respectively disposed at the first end and the second end of the gripping element, and located below the first sliding element, and communicate with the conduit unit for the main electrode unit to pass through the gripping element;

[0025] The second receiving element is disposed at the first end of the gripping element and above the auxiliary electrode hole element, and communicates with the conduit unit for the first bending adjustment unit to pass through the gripping element;

[0026] A third receiving element is disposed at the first end of the gripping element and located below the main electrode hole element, and communicates with the conduit unit for the second bending adjustment unit to pass through the gripping element.

[0027] In some embodiments, the catheter unit includes:

[0028] A catheter element comprising a curved section and a straight section, wherein a second end of the curved section is connected to a first end of the straight section, and a second end of the straight section of the catheter element is connected to a first end of the gripping unit;

[0029] A main electrode mounting element is disposed at the first end of the bend section of the conduit element and connected to the main electrode unit;

[0030] At least one auxiliary electrode mounting element is disposed at the first end of the bend section of the conduit element and connected to the auxiliary electrode unit.

[0031] A second injection port element is disposed through the catheter element and communicates with the gripping unit, for the telescopic injection unit to pass through the catheter element;

[0032] A fourth receiving element is disposed at the first end of the curved section of the conduit element, communicates with the second injection port element, and is connected to the telescopic injection unit for placing the telescopic injection unit.

[0033] At least one second sliding element is disposed at the first end of the bend section of the catheter element; and is in communication with the fourth receiving element and slidably connected to the telescopic injection unit;

[0034] A first rotating element is disposed at the first end of the bend section of the catheter element; and is connected to the fourth receiving element and rotatably connected to the telescopic injection unit;

[0035] A fifth receiving element is disposed at the second end of the straight section of the catheter element and communicates with the gripping unit and is connected to the first end of the first bending adjustment unit, for the first bending adjustment unit to pass through the catheter element;

[0036] A sixth receiving element is disposed at the second end of the straight section of the catheter element and communicates with the gripping unit and is connected to the first end of the second bending adjustment unit, for the second bending adjustment unit to pass through the catheter element;

[0037] A first auxiliary electrode placement element is disposed at the first end of the straight tube section of the conduit element and is connected to the gripping unit;

[0038] At least one second auxiliary electrode placement element is disposed inside the catheter element and communicates with the auxiliary electrode mounting element and the first auxiliary electrode placement element respectively, for cooperating with the first auxiliary electrode placement element to pass the auxiliary electrode unit through the catheter element;

[0039] A first main electrode placement element is disposed at the first end of the straight tube section of the conduit element and is connected to the gripping unit;

[0040] At least one second main electrode placement element is disposed inside the conduit element and communicates with the main electrode mounting element and the first main electrode placement element, respectively, for cooperating with the first main electrode placement element to pass the main electrode unit through the conduit element.

[0041] In some embodiments, the rotating unit includes:

[0042] The second rotating element is rotatably disposed inside the gripping unit and contacts the second bending adjustment unit;

[0043] An anti-detachment element is provided, the end of which is connected to the second rotating element to prevent the second bending adjustment unit from detaching from the second rotating element.

[0044] In some embodiments, the first bending adjustment unit includes:

[0045] A third sliding element is slidably connected to the gripping unit;

[0046] A first fixing element, the first end of which is connected to the third sliding element, is used to reciprocate along the axial direction of the gripping unit under the action of the third sliding element;

[0047] A first bending adjustment element, the first end of which is connected to the conduit unit, and the second end of which is connected to the second end of the first fixing element, are used to drive the curved section of the conduit unit to bend in the first direction under the action of the third sliding element.

[0048] In some embodiments, the second bending adjustment unit includes:

[0049] A fourth sliding element is slidably connected to the gripping unit;

[0050] The second fixing element has its first end connected to the fourth sliding element and is used to reciprocate along the axial direction of the gripping unit under the action of the fourth sliding element.

[0051] The second bending adjustment element has its first end bypassing the rotating unit and connected to the conduit unit, and its second end connected to the second end of the second fixing element. It is used to drive the curved section of the conduit unit to bend in the second direction under the action of the fourth sliding element.

[0052] In some embodiments, the main electrode unit includes:

[0053] The main electrode element is connected to the first end of the curved section of the catheter unit and is used to determine whether the first end of the curved section of the catheter unit is in close contact with the myocardium based on whether a damage current is detected by unipolar mapping.

[0054] A first signal transmission element, the first end of which is connected to the main electrode element, and the second end of which passes through the conduit unit and the gripping unit and is connected to the three-dimensional positioning device, for sending data to the remote control system.

[0055] In some embodiments, the auxiliary electrode unit includes:

[0056] An auxiliary electrode element is connected to the first end of the curved section of the catheter unit and is used to cooperate with the main electrode unit to map the position of the myocardium.

[0057] The second signal transmission element has a first end connected to the auxiliary electrode element and a second end passing through the conduit unit and the gripping unit and connected to the three-dimensional positioning device, for sending data to the remote control system.

[0058] In some embodiments, the limiting unit includes:

[0059] A base element is disposed at the top of the gripping unit and communicates with the gripping unit;

[0060] A first connecting element is disposed on the base element;

[0061] A control element, wherein the first end of the control element is located inside the base element, and the second end of the control element is located outside the base element and is rotatably connected to the first connecting element;

[0062] A limiting element is movably disposed inside the base element and connected to the first end of the control element, and abuts against the telescopic injection unit, for fixing the telescopic injection unit under the action of the control element.

[0063] In some embodiments, the telescopic injection unit includes:

[0064] A movable element, which is movably disposed inside the first end of the bend section of the conduit unit;

[0065] At least one fifth sliding element, the fifth sliding element being connected to the first end of the movable element and slidably connected to the first end of the bend section of the conduit unit;

[0066] A first injection element, which is connected to a first end of the movable element, is used for in situ injection into the myocardium;

[0067] A third rotating element is rotatably disposed inside the first end of the bend section of the conduit unit;

[0068] A fourth rotating element is rotatably disposed inside the first end of the bend section of the conduit unit. The second end of the fourth rotating element is connected to the first end of the third rotating element, and the first end of the fourth rotating element is rotatably connected to the second end of the movable element. The fourth rotating element is used to rotate under the action of the third rotating element so that the movable element reciprocates along the axial direction of the conduit unit.

[0069] A first transmission element is rotatably disposed inside the first end of the bend section of the conduit unit and connected to the second end of the third rotating element.

[0070] The second transmission element is rotatably disposed inside the first end of the bend section of the conduit unit and is connected to the first transmission element for driving the first transmission element to rotate.

[0071] A driving element is disposed inside the first end of the bend section of the conduit unit and is connected to the first end of the bend section of the conduit unit and the second transmission element, respectively, for driving the second transmission element to rotate;

[0072] The second injection element has a first end connected to the second end of the movable element, and the second end of the second injection element passes through the fourth rotating element, the third rotating element, the first transmission element, the conduit unit, the gripping unit, and the limiting unit to communicate with the liquid supply device and abuts against the limiting unit for fixation under the action of the limiting unit.

[0073] Secondly, the present invention provides a multifunctional in situ myocardial injection system, comprising:

[0074] The multifunctional myocardial in situ injection device as described in the first aspect;

[0075] A three-dimensional positioning device, which is connected to the main electrode unit and the auxiliary electrode unit of the multifunctional myocardial in situ injection device, is used to obtain whether the first end of the curved section of the catheter unit is in close contact with the myocardium and to obtain the position of the mapped myocardium.

[0076] A fluid supply device is provided, which is connected to the telescopic injection unit of the multifunctional myocardial in situ injection device, and is used to deliver injection fluid to the telescopic injection unit.

[0077] The present invention adopts the above technical solution and has the following technical effects compared with the prior art:

[0078] This invention discloses a multifunctional myocardial in situ injection device and system. A first bending adjustment unit and a second bending adjustment unit can adjust the relative curvature of the curved section of the catheter unit to better suit the structure of the myocardium. The potential between the main electrode unit and the auxiliary electrode unit can be used to mark the myocardial location of the first end of the catheter unit and determine whether the telescopic injection unit is in close contact with the heart, further enhancing its suitability for the myocardial structure. The telescopic injection unit can assist in advancing the injection needle, avoiding instability caused by manual advancement and improving injection stability. A limiting unit can stabilize the injection tubing of the telescopic injection unit, further improving stability. Attached Figure Description

[0079] Figure 1 This is a three-dimensional structural schematic diagram of a multifunctional myocardial in situ injection device according to an embodiment of the present invention;

[0080] Figure 2 This is a schematic diagram of the internal structure of a multifunctional myocardial in situ injection device according to an embodiment of the present invention;

[0081] Figure 3 This is a partial internal structure schematic diagram of a multifunctional myocardial in situ injection device according to an embodiment of the present invention;

[0082] Figure 4 This is a three-dimensional structural schematic diagram of the multifunctional myocardial in situ injection device according to an embodiment of the present invention;

[0083] Figure 5a This is a three-dimensional structural diagram of the gripping unit according to an embodiment of the present invention;

[0084] Figure 5b This is a schematic diagram of the internal structure of the gripping unit according to an embodiment of the present invention;

[0085] Figure 6aThis is a three-dimensional structural schematic diagram of a catheter unit according to an embodiment of the present invention;

[0086] Figure 6b This is a partial structural diagram of the internal structure of the catheter unit according to an embodiment of the present invention;

[0087] Figure 6c This is a schematic diagram of another part of the internal structure of the catheter unit according to an embodiment of the present invention;

[0088] Figure 7 This is a three-dimensional structural schematic diagram of the rotating unit according to an embodiment of the present invention;

[0089] Figure 8 This is a three-dimensional structural schematic diagram of the first bending adjustment unit according to an embodiment of the present invention;

[0090] Figure 9 This is a three-dimensional structural schematic diagram of the second bending adjustment unit according to an embodiment of the present invention;

[0091] Figure 10 This is a three-dimensional structural schematic diagram of the main electrode unit according to an embodiment of the present invention;

[0092] Figure 11 This is a three-dimensional structural schematic diagram of the auxiliary electrode unit according to an embodiment of the present invention;

[0093] Figure 12a This is a three-dimensional structural schematic diagram of the limiting unit according to an embodiment of the present invention;

[0094] Figure 12b This is an exploded view of the limiting unit according to an embodiment of the present invention;

[0095] Figure 13a This is an exploded view of the telescopic injection unit according to an embodiment of the present invention;

[0096] Figure 13b This is a schematic diagram of the internal structure of the telescopic injection unit according to an embodiment of the present invention;

[0097] Figure 14 This is a schematic diagram of the structure of an in-situ injection system according to an embodiment of the present invention;

[0098] The attached figures are labeled as follows: 100, Multifunctional in situ myocardial injection device;

[0099] 110. Grip unit; 111. Grip element; 112. First receiving element; 113. First sliding element; 114. First injection hole element; 115. Auxiliary electrode hole element; 116. Main electrode hole element; 117. Second receiving element; 118. Third receiving element;

[0100] 120. Catheter unit; 121. Catheter element; 122. Main electrode mounting element; 123. Auxiliary electrode mounting element; 124. Second injection port element; 125. Fourth receiving element; 126. Second sliding element; 127. First rotating element; 128. Fifth receiving element; 129. Sixth receiving element; 1210. First auxiliary electrode placement element; 1211. Second auxiliary electrode placement element; 1212. First main electrode placement element; 1213. Second main electrode placement element;

[0101] 130. Rotating unit; 131. Second rotating element; 132. Anti-detachment element;

[0102] 140. First bending adjustment unit; 141. Third sliding element; 142. First fixing element; 143. First bending adjustment element;

[0103] 150. Second bending adjustment unit; 151. Fourth sliding element; 152. Second fixing element; 153. Second bending adjustment element;

[0104] 160. Main electrode unit; 161. Main electrode element; 162. First signal transmission element;

[0105] 170. Auxiliary electrode unit; 171. Auxiliary electrode element; 172. Second signal transmission element;

[0106] 180. Limiting unit; 181. Base element; 182. First connecting element; 183. Control element; 184. Limiting element;

[0107] 190. Telescopic injection unit; 191. Movable element; 192. Fifth sliding element; 193. First injection element; 194. Third rotating element; 195. Fourth rotating element; 196. First transmission element; 197. Second transmission element; 198. Drive element; 199. Second injection element;

[0108] 200. Three-dimensional positioning device;

[0109] 300. Liquid supply device. Detailed Implementation

[0110] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0111] It should be noted that, unless otherwise specified, the embodiments and features described in the present invention can be combined with each other.

[0112] The present invention will be further described below with reference to the accompanying drawings and specific embodiments, but this is not intended to limit the scope of the invention.

[0113] Example 1

[0114] This embodiment relates to the multifunctional myocardial in situ injection device of the present invention.

[0115] An illustrative embodiment of the present invention, such as Figure 1 , Figure 2 , Figure 3 , Figure 4As shown, a multifunctional myocardial in situ injection device 100 for myocardial endometrium includes a gripping unit 110, a catheter unit 120, a rotating unit 130, a first bending adjustment unit 140, a second bending adjustment unit 150, a main electrode unit 160, at least one auxiliary electrode unit 170, a limiting unit 180, and a telescopic injection unit 190. The device includes a gripping unit 110 for user gripping; a conduit unit 120 comprising a curved section and a straight section, the second end of the curved section being connected to the first end of the straight section, and the second end of the straight section of the conduit unit 120 being connected to the first end of the gripping unit 110; a rotating unit 130 rotatably disposed inside the gripping unit 110; a first bending adjustment unit 140 having its first end connected to the second end of the curved section of the conduit unit 120, and the second end of the first bending adjustment unit 140 being slidably connected to the gripping unit 110, for bending the curved section of the conduit unit 120 in a first direction; a second bending adjustment unit 150 having its first end connected to the second end of the curved section of the conduit unit 120, and the second end of the second bending adjustment unit 150 bypassing the rotating unit 130 and being slidably connected to the gripping unit 110, for bending the curved section of the conduit unit 120 in a second direction, wherein the second direction is opposite to the first direction; and a main electrode unit 160 having its first end connected to the first end of the curved section of the conduit unit 120, the main electrode unit 160... The second end of the auxiliary electrode unit 170 passes through the catheter unit 120 and the holding unit 110 and is connected to the three-dimensional positioning device. It is used to determine whether the first end of the curved section of the catheter unit 120 is in close contact with the myocardium based on whether a damage current appears in the monopolar mapping and to send data to the remote control system. The first end of the auxiliary electrode unit 170 is connected to the first end of the curved section of the catheter unit 120. The second end of the auxiliary electrode unit 170 passes through the catheter unit 120 and the holding unit 110 and is connected to the three-dimensional positioning device. It is used to cooperate with the main electrode unit 160 to map the position of the myocardium and to send data to the remote control system. The limiting unit 180 is disposed at the top of the holding unit 110 and communicates with the holding unit 110. The first end of the telescopic injection unit 190 is slidably connected to the first end of the curved section of the catheter unit 120. The second end of the telescopic injection unit 190 passes through the catheter unit 120, the holding unit 110, and the limiting unit 180 and communicates with the liquid supply device and abuts against the limiting unit 180. It is used to perform in situ injection of the myocardium and to fix it under the action of the limiting unit 180.

[0116] Specifically, the operator holds the multifunctional myocardial in situ injection device 100 through the gripping unit 110; inserts the catheter unit 120 deep into the myocardium; adjusts the curvature of the curved section of the catheter unit 120 through the first curvature adjustment unit 140 / second curvature adjustment unit 150; maps the position of the myocardium and sends data to the remote control system through the combined use of the main electrode unit 160 and the auxiliary electrode unit 170; fixes the position of the telescopic injection unit 190 using the limiting unit 180; and performs in situ injection into the myocardium through the telescopic injection unit 190.

[0117] like Figure 5a , Figure 5b As shown, the gripping unit 110 includes a gripping element 111, a first receiving element 112, a first sliding element 113, a first injection hole element 114, two auxiliary electrode hole elements 115, two main electrode hole elements 116, a second receiving element 117, and a third receiving element 118. The gripping element 111 has its first end connected to the second end of the straight section of the catheter unit 120, its top end connected to the bottom end of the limiting unit 180, and its interior rotatably connected to the rotating unit 130 for user gripping. A first receiving element 112 is located at the top of the gripping element 111 and communicates with the limiting unit 180, allowing the telescopic injection unit 190 to pass through the gripping element 111. A first sliding element 113 is located at the front end of the gripping element 111 and is slidably connected to the first bending adjustment unit 140 and the second bending adjustment unit 150, respectively. A first injection hole element 114 is located at the first end of the gripping element 111 and communicates with the catheter unit 120, allowing the telescopic injection unit 190 to pass through the gripping element 111. Two auxiliary electrode hole elements 115 are located at the first end of the gripping element 111 and the second end of the catheter unit 120, respectively. The second end, located above the first sliding element 113 and connected to the conduit unit 120, is used for the auxiliary electrode unit 170 to pass through the gripping element 111; the two main electrode hole elements 116 are respectively disposed at the first end and the second end of the gripping element 111, located below the first sliding element 113 and connected to the conduit unit 120, for the main electrode unit 160 to pass through the gripping element 111; the second receiving element 117 is disposed at the first end of the gripping element 111, located above the auxiliary electrode hole element 115 and connected to the conduit unit 120, for the first bending adjustment unit 140 to pass through the gripping element 111; the third receiving element 118 is disposed at the first end of the gripping element 111, located below the main electrode hole element 116 and connected to the conduit unit 120, for the second bending adjustment unit 150 to pass through the gripping element 111.

[0118] The gripping element 111 has a hollow structure.

[0119] The cross-section of the holding element 111 is a rounded rectangle.

[0120] In some of these embodiments, the gripping element 111 is made of plastic.

[0121] In some of these embodiments, the gripping element 111 is a housing.

[0122] The first receiving element 112 has a rectangular cross-section.

[0123] The dimensions of the first receiving element 112 are matched with the dimensions of the holding element 111. Generally, the length of the first receiving element 112 is less than the inner length of the holding element 111, the width of the first receiving element 112 is less than the inner width of the holding element 111, and the height (e.g., depth) of the first receiving element 112 is equal to the top wall thickness of the holding element 111.

[0124] In some of these embodiments, the first receiving element 112 is a first receiving cavity.

[0125] The cross-section of the first sliding element 113 is rectangular.

[0126] The dimensions of the first sliding element 113 are matched with the dimensions of the gripping element 111. Generally, the length of the first sliding element 113 is less than the inner length of the gripping element 111, the width (e.g., depth) of the first sliding element 113 is equal to the front wall thickness of the gripping element 111, and the height of the first sliding element 113 is less than the inner height of the gripping element 111.

[0127] In some of these embodiments, the first sliding element 113 is a first sliding groove.

[0128] The first injection hole element 114 has a circular cross-section.

[0129] The dimensions of the first injection hole element 114 are matched with the dimensions of the gripping element 111. Generally, the diameter of the first injection hole element 114 is smaller than the inner width / inner height of the gripping element 111, and the axial dimension (e.g., depth) of the first injection hole element 114 is equal to the sidewall thickness of the gripping element 111.

[0130] In some of these embodiments, the first injection hole element 114 is a first injection hole.

[0131] The cross-section of the auxiliary electrode hole element 115 is circular.

[0132] The dimensions of the auxiliary electrode hole element 115 are matched with the dimensions of the gripping element 111. Generally, the diameter of the auxiliary electrode hole element 115 is smaller than the inner width / inner height of the gripping element 111, and the axial dimension (such as depth) of the auxiliary electrode hole element 115 is equal to the sidewall thickness of the gripping element 111.

[0133] In some of these embodiments, the auxiliary electrode hole element 115 is an auxiliary electrode through hole.

[0134] The cross-section of the main electrode hole element 116 is circular.

[0135] The dimensions of the main electrode hole element 116 are matched with the dimensions of the gripping element 111. Generally, the diameter of the main electrode hole element 116 is smaller than the inner width / inner height of the gripping element 111, and the axial dimension (e.g., depth) of the main electrode hole element 116 is equal to the sidewall thickness of the gripping element 111.

[0136] The dimensions of the main electrode hole element 116 are matched with the dimensions of the auxiliary electrode hole element 115. Generally, the diameter of the main electrode hole element 116 is equal to the diameter of the auxiliary electrode hole element 115, and the axial dimension (e.g., depth) of the main electrode hole element 116 is equal to the axial dimension (e.g., depth) of the auxiliary electrode hole element 115.

[0137] In some of these embodiments, the main electrode hole element 116 is the main electrode through hole.

[0138] The cross-section of the second receiving element 117 is circular.

[0139] The dimensions of the second receiving element 117 are matched with the dimensions of the gripping element 111. Generally, the diameter of the second receiving element 117 is smaller than the inner width / inner height of the gripping element 111, and the axial dimension (e.g., depth) of the second receiving element 117 is equal to the sidewall thickness of the gripping element 111.

[0140] In some of these embodiments, the second receiving element 117 is a second receiving cavity.

[0141] The cross-section of the third receiving element 118 is circular.

[0142] The dimensions of the third receiving element 118 are matched with the dimensions of the gripping element 111. Generally, the diameter of the third receiving element 118 is smaller than the inner width / inner height of the gripping element 111, and the axial dimension (e.g., depth) of the third receiving element 118 is equal to the sidewall thickness of the gripping element 111.

[0143] The dimensions of the third receiving element 118 are matched with the dimensions of the second receiving element 117. Generally, the diameter of the third receiving element 118 is equal to the diameter of the second receiving element 117, and the axial dimension (e.g., depth) of the third receiving element 118 is equal to the axial dimension (e.g., depth) of the second receiving element 117.

[0144] In some of these embodiments, the third receiving element 118 is a third receiving cavity.

[0145] like Figure 6a , Figure 6b , Figure 6cAs shown, the catheter unit 120 includes a catheter element 121, a main electrode mounting element 122, at least one auxiliary electrode mounting element 123, a second injection hole element 124, a fourth receiving element 125, at least one second sliding element 126, a first rotating element 127, a fifth receiving element 128, a sixth receiving element 129, a first auxiliary electrode placement element 1210, at least one second auxiliary electrode placement element 1211, a first main electrode placement element 1212, and at least one second main electrode placement element 1213.The catheter element 121 includes a curved section and a straight section. The second end of the curved section is connected to the first end of the straight section, and the second end of the straight section is connected to the first end of the holding unit 110. The main electrode mounting element 122 is disposed at the first end of the curved section of the catheter element 121 and is connected to the main electrode unit 160. The auxiliary electrode mounting element 123 is disposed at the first end of the curved section of the catheter element 121 and is connected to the auxiliary electrode unit 170. The second injection hole element 124 is disposed through the catheter element 121 and communicates with the holding unit 110, for allowing the telescopic injection unit 190 to pass through the catheter element 121. A fourth receiving element 125 is disposed at the first end of the bend section of the conduit element 121, and communicates with the second injection port element 124 and is connected to the telescopic injection unit 190 for housing the telescopic injection unit 190; a second sliding element 126 is disposed at the first end of the bend section of the conduit element 121, and communicates with the fourth receiving element 125 and is slidably connected to the telescopic injection unit 190; a first rotating element 127 is disposed at the first end of the bend section of the conduit element 121, and communicates with the fourth receiving element 125 and is rotatably connected to the telescopic injection unit 190; a fifth receiving element 128 is disposed at the first end of the straight section of the conduit element 121. The second end is connected to the gripping unit 110 and the first end of the first bending adjustment unit 140, for the first bending adjustment unit 140 to pass through the catheter element 121; the sixth receiving element 129 is disposed at the second end of the straight section of the catheter element 121, and is connected to the gripping unit 110 and the first end of the second bending adjustment unit 150, for the second bending adjustment unit 150 to pass through the catheter element 121; the first auxiliary electrode placement element 1210 is disposed at the first end of the straight section of the catheter element 121 and is connected to the gripping unit 110; the second auxiliary electrode placement element 1211 is disposed at the second end of the straight section of the catheter element 121. The first main electrode placement element 1212 is located inside the conduit element 121 and is connected to the auxiliary electrode mounting element 123 and the first auxiliary electrode placement element 1210 respectively. It is used to cooperate with the first auxiliary electrode placement element 1210 to pass the auxiliary electrode unit 170 through the conduit element 121. The first main electrode placement element 1212 is located at the first end of the straight tube section of the conduit element 121 and is connected to the holding unit 110. The second main electrode placement element 1213 is located inside the conduit element 121 and is connected to the main electrode mounting element 122 and the first main electrode placement element 1212 respectively. It is used to cooperate with the first main electrode placement element 1212 to pass the main electrode unit 160 through the conduit element 121.

[0146] Specifically, the second end of the straight tube section of the catheter element 121 is connected to the first end of the holding element 111; the second injection hole element 124 is connected to the first injection hole element 114; the fifth receiving element 128 is connected to the second receiving element 117; the sixth receiving element 129 is connected to the third receiving element 118; the first auxiliary electrode placement element 1210 is connected to the auxiliary electrode hole element 115; and the first main electrode placement element 1212 is connected to the main electrode hole element 116.

[0147] The cross-section of the conduit element 121 is circular.

[0148] The longitudinal section of the bend is an isosceles trapezoid. Specifically, the radial dimension (such as diameter) of the bend increases from its first end to its second end.

[0149] The dimensions of the bend section are matched with those of the straight section. Generally, the radial dimension (i.e., the maximum radial dimension) of the second end of the bend section is equal to the radial dimension of the straight section.

[0150] The dimensions of the catheter element 121 are matched with the dimensions of the holding element 111. Generally, the radial dimension (e.g., diameter) of the straight section of the catheter element 121 is not greater than the width / height of the holding element 111, and the axial dimension of the catheter element 121 is greater than the length of the holding element 111.

[0151] In some embodiments, the conduit element 121 is fixedly connected to the gripping element 111, including but not limited to thermofusion welding.

[0152] In some of these embodiments, the conduit element 121 is an adjustable conduit made of a thermoplastic elastic polymer material.

[0153] The cross-section of the main electrode mounting element 122 is circular.

[0154] The longitudinal section of the main electrode mounting element 122 is an isosceles trapezoid. Specifically, the radial dimension (e.g., diameter) of the main electrode mounting element 122 increases from its first end to its second end.

[0155] The dimensions of the main electrode mounting element 122 are matched with the dimensions of the conduit element 121. Generally, the radial dimension (e.g., minimum outer edge, maximum outer edge) of the main electrode mounting element 122 is not less than the radial dimension (e.g., minimum diameter, maximum diameter) of the bend section of the conduit element 121, and the axial dimension of the main electrode mounting element 122 is less than the axial dimension of the bend section of the conduit element 121.

[0156] In some of these embodiments, the main electrode mounting element 122 is the main electrode mounting slot.

[0157] The cross-section of the auxiliary electrode mounting element 123 is circular.

[0158] The dimensions of the auxiliary electrode mounting element 123 are matched with the dimensions of the conduit element 121. Generally, the radial dimension (e.g., outer edge) of the auxiliary electrode mounting element 123 is not less than the radial dimension (e.g., maximum diameter) of the bend section of the conduit element 121, and the axial dimension of the auxiliary electrode mounting element 123 is less than the axial dimension of the bend section of the conduit element 121.

[0159] When there are multiple auxiliary electrode mounting elements 123, the multiple auxiliary electrode mounting elements 123 are distributed along the axial direction of the conduit element 121.

[0160] In some embodiments, there may be 1 to 7 auxiliary electrode mounting elements 123.

[0161] In some of these embodiments, the auxiliary electrode mounting element 123 is an auxiliary electrode mounting slot.

[0162] The cross-section of the second injection hole element 124 is circular.

[0163] The dimensions of the second injection hole element 124 are matched with the dimensions of the catheter element 121. Generally, the diameter of the second injection hole element 124 is smaller than the diameter of the catheter element 121, and the axial dimension of the second injection hole element 124 is equal to the axial dimension of the catheter element 121.

[0164] The dimensions of the second injection hole element 124 are matched with the dimensions of the first injection hole element 114. Generally, the diameter of the second injection hole element 124 is equal to the diameter of the first injection hole element 114, and the axial dimension of the second injection hole element 124 is greater than the axial dimension of the first injection hole element 114.

[0165] In some of these embodiments, the second injection hole element 124 is a second injection hole.

[0166] The fourth receiving element 125 has a circular cross-section.

[0167] The dimensions of the fourth receiving element 125 are matched with the dimensions of the catheter element 121. Generally, the diameter of the fourth receiving element 125 is smaller than the diameter of the catheter element 121, and the axial dimension of the fourth receiving element 125 is smaller than the axial dimension of the catheter element 121.

[0168] The dimensions of the fourth receiving element 125 are matched with the dimensions of the second injection hole element 124. Generally, the diameter of the fourth receiving element 125 is larger than the diameter of the second injection hole element 124, and the axial dimension of the fourth receiving element 125 is smaller than the axial dimension of the second injection hole element 124.

[0169] In some of these embodiments, the fourth receiving element 125 is a fourth receiving cavity.

[0170] The cross-section of the second sliding element 126 is rectangular.

[0171] The dimensions of the second sliding element 126 are matched with the dimensions of the fourth receiving element 125. Generally, the length of the second sliding element 126 is less than the axial dimension of the fourth receiving element 125, and the height / width of the second sliding element 126 is less than the diameter of the fourth receiving element 125.

[0172] There are multiple second sliding elements 126. When there are multiple second sliding elements 126, the multiple second sliding elements 126 are arranged circumferentially along the fourth receiving element 125.

[0173] Generally, there are two second sliding elements 126. The two second sliding elements 126 are arranged opposite to each other.

[0174] In some of these embodiments, the second sliding element 126 is a second sliding groove.

[0175] The cross-section of the first rotating element 127 is circular.

[0176] The dimensions of the first rotating element 127 are matched with the dimensions of the catheter element 121. Generally, the diameter of the first rotating element 127 is smaller than the diameter of the catheter element 121, and the axial dimension of the first rotating element 127 is smaller than the axial dimension of the catheter element 121.

[0177] The dimensions of the first rotating element 127 are matched with the dimensions of the fourth receiving element 125. Generally, the diameter of the first rotating element 127 is larger than the diameter of the fourth receiving element 125, and the axial dimension of the first rotating element 127 is smaller than the axial dimension of the fourth receiving element 125.

[0178] In some of these embodiments, the first rotating element 127 is a rotating groove.

[0179] The fifth receiving element 128 has a circular cross-section.

[0180] The dimensions of the fifth receiving element 128 are matched with the dimensions of the catheter element 121. Generally, the diameter of the fifth receiving element 128 is smaller than the diameter of the catheter element 121, and the axial dimension of the fifth receiving element 128 is smaller than the axial dimension of the catheter element 121.

[0181] The dimensions of the fifth receiving element 128 are matched with those of the second receiving element 117. Generally, the diameter of the fifth receiving element 128 is equal to the diameter of the second receiving element 117, and the axial dimension of the fifth receiving element 128 is greater than the axial dimension of the second receiving element 117.

[0182] In some of these embodiments, the fifth receiving element 128 is a fifth receiving cavity.

[0183] The sixth housing element 129 has a circular cross-section.

[0184] The dimensions of the sixth receiving element 129 are matched with the dimensions of the catheter element 121. Generally, the diameter of the sixth receiving element 129 is smaller than the diameter of the catheter element 121, and the axial dimension of the sixth receiving element 129 is smaller than the axial dimension of the catheter element 121.

[0185] The dimensions of the sixth receiving element 129 are matched with those of the third receiving element 118. Generally, the diameter of the sixth receiving element 129 is equal to the diameter of the third receiving element 118, and the axial dimension of the sixth receiving element 129 is greater than the axial dimension of the third receiving element 118.

[0186] The dimensions of the sixth receiving element 129 are matched with those of the fifth receiving element 128. Generally, the diameter of the sixth receiving element 129 is equal to the diameter of the fifth receiving element 128, and the axial dimension of the sixth receiving element 129 is equal to the axial dimension of the fifth receiving element 128.

[0187] In some of these embodiments, the sixth receiving element 129 is a sixth receiving cavity.

[0188] The cross-section of the first auxiliary electrode placement element 1210 is circular.

[0189] The dimensions of the first auxiliary electrode placement element 1210 are matched with the dimensions of the catheter element 121. Generally, the diameter of the first auxiliary electrode placement element 1210 is smaller than the diameter of the catheter element 121, and the axial dimension of the first auxiliary electrode placement element 1210 is smaller than the axial dimension of the catheter element 121.

[0190] The dimensions of the first auxiliary electrode placement element 1210 are matched with the dimensions of the auxiliary electrode hole element 115. Generally, the diameter of the first auxiliary electrode placement element 1210 is equal to the diameter of the auxiliary electrode hole element 115, and the axial dimension of the first auxiliary electrode placement element 1210 is greater than the axial dimension of the auxiliary electrode hole element 115.

[0191] In some of these embodiments, the first auxiliary electrode placement element 1210 is an auxiliary electrode placement cavity.

[0192] The cross-section of the second auxiliary electrode placement element 1211 is circular.

[0193] The dimensions of the second auxiliary electrode placement element 1211 are matched with the dimensions of the catheter element 121. Generally, the diameter of the second auxiliary electrode placement element 1211 is smaller than the diameter and axial dimension of the catheter element 121, and the axial dimension of the second auxiliary electrode placement element 1211 is smaller than the diameter of the catheter element 121.

[0194] The dimensions of the second auxiliary electrode placement element 1211 are matched with the dimensions of the first auxiliary electrode placement element 1210. Generally, the diameter of the second auxiliary electrode placement element 1211 is equal to the diameter of the first auxiliary electrode placement element 1210, and the axial dimension of the second auxiliary electrode placement element 1211 is smaller than the axial dimension of the first auxiliary electrode placement element 1210.

[0195] The dimensions of the second auxiliary electrode placement element 1211 are matched with the dimensions of the auxiliary electrode mounting element 123. Generally, the diameter of the second auxiliary electrode placement element 1211 is smaller than the axial dimension of the auxiliary electrode mounting element 123.

[0196] The number of second auxiliary electrode placement elements 1211 matches the number of auxiliary electrode mounting elements 123. Generally, the number of second auxiliary electrode placement elements 1211 is equal to the number of auxiliary electrode mounting elements 123.

[0197] In some of these embodiments, the second auxiliary electrode placement element 1211 is an auxiliary electrode through hole.

[0198] The cross-section of the first main electrode placement element 1212 is circular.

[0199] The dimensions of the first main electrode placement element 1212 are matched with the dimensions of the conduit element 121. Generally, the diameter of the first main electrode placement element 1212 is smaller than the diameter and axial dimension of the conduit element 121, and the axial dimension of the first main electrode placement element 1212 is smaller than the diameter of the conduit element 121.

[0200] The dimensions of the first main electrode placement element 1212 are matched with the dimensions of the main electrode hole element 116. Generally, the diameter of the first main electrode placement element 1212 is equal to the diameter of the main electrode hole element 116, and the axial dimension of the first main electrode placement element 1212 is greater than the axial dimension of the main electrode hole element 116.

[0201] The dimensions of the first main electrode placement element 1212 are matched with the dimensions of the first auxiliary electrode placement element 1210. Generally, the diameter of the first main electrode placement element 1212 is equal to the diameter of the first auxiliary electrode placement element 1210, and the axial dimension of the first main electrode placement element 1212 is equal to the axial dimension of the first auxiliary electrode placement element 1210.

[0202] In some of these embodiments, the first main electrode placement element 1212 is the main electrode placement cavity.

[0203] The cross-section of the second main electrode placement element 1213 is circular.

[0204] The dimensions of the second main electrode placement element 1213 are matched with the dimensions of the catheter element 121. Generally, the diameter of the second main electrode placement element 1213 is smaller than the diameter and axial dimension of the catheter element 121, and the axial dimension of the second main electrode placement element 1213 is smaller than the diameter of the catheter element 121.

[0205] The dimensions of the second main electrode placement element 1213 are matched with the dimensions of the first main electrode placement element 1212. Generally, the diameter of the second main electrode placement element 1213 is equal to the diameter of the first main electrode placement element 1212, and the axial dimension of the second main electrode placement element 1213 is smaller than the axial dimension of the first main electrode placement element 1212.

[0206] The dimensions of the second main electrode placement element 1213 are matched with the dimensions of the main electrode mounting element 122. Generally, the diameter of the second main electrode placement element 1213 is smaller than the axial dimension of the main electrode mounting element 122.

[0207] The dimensions of the second main electrode placement element 1213 are matched with the dimensions of the second auxiliary electrode placement element 1211. Generally, the diameter of the second main electrode placement element 1213 is equal to the diameter of the second auxiliary electrode placement element 1211, and the axial dimension of the second main electrode placement element 1213 is equal to the axial dimension of the second auxiliary electrode placement element 1211.

[0208] In some of these embodiments, the second main electrode placement element 1213 is a main electrode via.

[0209] like Figure 7 As shown, the rotating unit 130 includes a second rotating element 131 and an anti-detachment element 132. The second rotating element 131 is rotatably disposed inside the gripping unit 110 and is in contact with the second bending adjustment unit 150; the end of the anti-detachment element 132 is connected to the second rotating element 131 to prevent the second bending adjustment unit 150 from detaching from the second rotating element 131.

[0210] Specifically, the second rotating element 131 is rotatably disposed inside the gripping element 111.

[0211] In some embodiments, the second rotating element 131 includes a rotating shaft and a guide wheel. Specifically, the two ends of the rotating shaft are rotatably connected to the interior of the gripping element 111; the guide wheel is coaxially arranged with the rotating shaft and contacts the second bending adjustment unit 150.

[0212] The dimensions of the pivot are matched with the dimensions of the gripping element 111. Generally, the diameter of the pivot is smaller than the inner length / inner height of the gripping element 111, and the axial dimension of the pivot is equal to the inner width of the gripping element 111.

[0213] The size of the guide wheel matches the size of the gripping element 111. Generally, the diameter of the guide wheel is smaller than the inner length / inner height of the gripping element 111, and the axial dimension of the guide wheel is smaller than the inner width of the gripping element 111.

[0214] The dimensions of the guide wheel are matched with the dimensions of the shaft. Generally, the inner diameter of the guide wheel is equal to the diameter of the shaft, and the axial dimension of the guide wheel is smaller than the axial dimension of the shaft.

[0215] In some embodiments, the second rotating element 131 and the gripping element 111 are rotatably connected without separation. For example, the second rotating element 131 and the gripping element 111 are connected via a bearing housing.

[0216] In some of these embodiments, the second rotating element 131 is made of plastic.

[0217] In some of these embodiments, the second rotating element 131 is a guide wheel.

[0218] The cross-section of the anti-detachment element 132 is rectangular.

[0219] The end of the anti-detachment element 132 is connected to the guide wheel.

[0220] The dimensions of the anti-detachment element 132 are matched with the dimensions of the guide wheel. Generally, the length of the anti-detachment element 132 is equal to the axial dimension of the guide wheel, and the width / height of the anti-detachment element 132 is less than the diameter of the guide wheel.

[0221] In some embodiments, the anti-detachment element 132 is fixedly connected to the second rotating element 131, including but not limited to hot-melt welding.

[0222] In some of these embodiments, the anti-detachment element 132 is made of plastic.

[0223] In some of these embodiments, the anti-detachment element 132 is a baffle plate.

[0224] like Figure 8 As shown, the first bending adjustment unit 140 includes a third sliding element 141, a first fixing element 142, and a first bending adjustment element 143. The third sliding element 141 is slidably connected to the gripping unit 110; the first end of the first fixing element 142 is connected to the third sliding element 141 and is used to reciprocate along the axial direction of the gripping unit 110 under the action of the third sliding element 141; the first end of the first bending adjustment element 143 is connected to the conduit unit 120, and the second end of the first bending adjustment element 143 is connected to the second end of the first fixing element 142, used to drive the curved section of the conduit unit 120 to bend in a first direction under the action of the third sliding element 141.

[0225] Specifically, the third sliding element 141 is slidably connected to the first sliding element 113; the first end of the first bending adjustment element 143 passes through the second receiving element 117 and is connected to the first end of the fifth receiving element 128.

[0226] The third sliding element 141 includes a first outer slider, a first connecting block, and a first inner slider. Specifically, the first outer slider is slidably disposed outside the gripping element 111; the first end of the first connecting block is connected to the first outer slider and slidably connected to the first sliding element 113; the first inner slider is slidably disposed inside the gripping element 111 and is connected to the second end of the first connecting block.

[0227] The dimensions of the first outer slider are matched with the dimensions of the gripping element 111. Generally, the length of the first outer slider is less than the outer length of the gripping element 111, the width of the first outer slider is less than the outer width of the gripping element 111, and the height of the first outer slider is less than the outer height of the gripping element 111.

[0228] The dimensions of the first outer slider are matched with the dimensions of the first sliding element 113. Generally, the length of the first outer slider is less than the length of the first sliding element 113, the width of the first outer slider is less than the width (e.g., depth) of the first sliding element 113, and the height of the first outer slider is greater than the height of the first sliding element 113.

[0229] The dimensions of the first connecting block are matched with the dimensions of the first sliding element 113. Generally, the length of the first connecting block is less than the length of the first sliding element 113, the width of the first connecting block is equal to the width (e.g., depth) of the first sliding element 113, and the height of the first connecting block is equal to the height of the first sliding element 113.

[0230] The dimensions of the first connecting block match the dimensions of the first outer slider. Generally, the length of the first connecting block is equal to the length of the first outer slider, the width of the first connecting block is greater than the width of the first outer slider, and the height of the first connecting block is less than the height of the first outer slider.

[0231] The dimensions of the first inner slider are matched with the dimensions of the gripping element 111. Generally, the length of the first inner slider is less than the inner length of the gripping element 111, the width of the first inner slider is less than the inner width of the gripping element 111, and the height of the first inner slider is less than the inner height of the gripping element 111.

[0232] The dimensions of the first inner slider are matched with the dimensions of the first sliding element 113. Generally, the length of the first inner slider is less than the length of the first sliding element 113, the width of the first inner slider is less than the width (e.g., depth) of the first sliding element 113, and the height of the first inner slider is greater than the height of the first sliding element 113.

[0233] The dimensions of the first inner slider are matched with the dimensions of the first outer slider. Generally, the length of the first inner slider is greater than the length of the first outer slider, the width of the first inner slider is equal to the width of the first outer slider, and the height of the first inner slider is equal to the height of the first outer slider.

[0234] The dimensions of the first connecting block are matched with the dimensions of the first inner slider. Generally, the length of the first connecting block is less than the length of the first inner slider, the width of the first connecting block is greater than the width of the first inner slider, and the height of the first connecting block is less than the height of the first inner slider.

[0235] In some of these embodiments, the third sliding element 141 is made of plastic.

[0236] In some of these embodiments, the third sliding element 141 is the first sliding block.

[0237] The first end of the first fixing element 142 is connected to the first inner slider.

[0238] The cross-section of the first fixing element 142 is rectangular.

[0239] The dimensions of the first fixing element 142 are matched with the dimensions of the third sliding element 141. Generally, the length of the first fixing element 142 is greater than the width of the first inner slider, the width of the first fixing element 142 is less than the length of the first inner slider, and the height of the first fixing element 142 is less than the height of the first inner slider.

[0240] In some embodiments, the first fixing element 142 is fixedly connected to the third sliding element 141. For example, the first fixing element 142 and the third sliding element 141 are integrally formed.

[0241] In some of these embodiments, the first fixing element 142 is made of plastic.

[0242] In some of these embodiments, the first fixing element 142 is a first fixing base.

[0243] The cross-section of the first bending adjustment element 143 is circular.

[0244] The dimensions of the first bending adjustment element 143 are matched with the dimensions of the first fixing element 142. Generally, the diameter of the first bending adjustment element 143 is smaller than the length / height of the first fixing element 142.

[0245] The dimensions of the first bending adjustment element 143 are matched with the dimensions of the second receiving element 117. Generally, the diameter of the first bending adjustment element 143 is smaller than the diameter of the second receiving element 117, and the axial dimension of the first bending adjustment element 143 is larger than the axial dimension (e.g., depth) of the second receiving element 117.

[0246] The dimensions of the first bending adjustment element 143 are matched with the dimensions of the fifth receiving element 128. Generally, the diameter of the first bending adjustment element 143 is smaller than the diameter of the fifth receiving element 128, and the axial dimension of the first bending adjustment element 143 is larger than the axial dimension (e.g., depth) of the fifth receiving element 128.

[0247] In some of these embodiments, the first bending adjustment element 143 is fixedly connected to the fifth receiving element 128.

[0248] In some of these embodiments, the first bending adjustment element 143 is made of stainless steel.

[0249] In some of these embodiments, the first bending adjustment element 143 is a first linkage rod.

[0250] like Figure 9 As shown, the second bending adjustment unit 150 includes a fourth sliding element 151, a second fixing element 152, and a second bending adjustment element 153. The fourth sliding element 151 is slidably connected to the gripping unit 110; the first end of the second fixing element 152 is connected to the fourth sliding element 151 and is used to reciprocate along the axial direction of the gripping unit 110 under the action of the fourth sliding element 151; the first end of the second bending adjustment element 153 passes around the rotating unit 130 and is connected to the conduit unit 120, and the second end of the second bending adjustment element 153 is connected to the second end of the second fixing element 152, used to drive the curved section of the conduit unit 120 to bend in a second direction under the action of the fourth sliding element 151.

[0251] Specifically, the fourth sliding element 151 is slidably connected to the first sliding element 113; the first end of the second bending adjustment element 153 passes through the third receiving element 118 and is connected to the first end of the sixth receiving element 129; the second bending adjustment element 153 is in contact with the second rotating element 131.

[0252] The fourth sliding element 151 includes a second outer slider, a second connecting block, and a second inner slider. Specifically, the second outer slider is slidably disposed outside the gripping element 111; the first end of the second connecting block is connected to the second outer slider and slidably connected to the first sliding element 113; the second inner slider is slidably disposed inside the gripping element 111 and is connected to the second end of the second connecting block.

[0253] The dimensions of the second outer slider are matched with the dimensions of the gripping element 111. Generally, the length of the second outer slider is less than the outer length of the gripping element 111, the width of the second outer slider is less than the outer width of the gripping element 111, and the height of the second outer slider is less than the outer height of the gripping element 111.

[0254] The dimensions of the second outer slider are matched with the dimensions of the first sliding element 113. Generally, the length of the second outer slider is less than the length of the first sliding element 113, the width of the second outer slider is less than the width (e.g., depth) of the first sliding element 113, and the height of the second outer slider is greater than the height of the first sliding element 113.

[0255] The dimensions of the second outer slider match those of the first outer slider. Generally, the length of the second outer slider is equal to the length of the first outer slider, the width of the second outer slider is equal to the width of the first outer slider, and the height of the second outer slider is equal to the height of the first outer slider.

[0256] The dimensions of the second connecting block are matched with the dimensions of the first sliding element 113. Generally, the length of the second connecting block is less than the length of the first sliding element 113, the width of the second connecting block is equal to the width (e.g., depth) of the first sliding element 113, and the height of the second connecting block is equal to the height of the first sliding element 113.

[0257] The dimensions of the second connecting block match those of the first connecting block. Generally, the length of the second connecting block is equal to the length of the first connecting block, the width of the second connecting block is equal to the width of the first connecting block, and the height of the second connecting block is equal to the height of the first connecting block.

[0258] The dimensions of the second connecting block match the dimensions of the second outer slider. Generally, the length of the second connecting block is equal to the length of the second outer slider, the width of the second connecting block is greater than the width of the second outer slider, and the height of the second connecting block is less than the height of the second outer slider.

[0259] The dimensions of the second inner slider are matched with the dimensions of the gripping element 111. Generally, the length of the second inner slider is less than the inner length of the gripping element 111, the width of the second inner slider is less than the inner width of the gripping element 111, and the height of the second inner slider is less than the inner height of the gripping element 111.

[0260] The dimensions of the second inner slider are matched with the dimensions of the first sliding element 113. Generally, the length of the second inner slider is less than the length of the first sliding element 113, the width of the second inner slider is less than the width (e.g., depth) of the first sliding element 113, and the height of the second inner slider is greater than the height of the first sliding element 113.

[0261] The dimensions of the second inner slider match those of the first inner slider. Generally, the length of the second inner slider is equal to the length of the first inner slider, the width of the second inner slider is equal to the width of the first inner slider, and the height of the second inner slider is equal to the height of the first inner slider.

[0262] The dimensions of the second inner slider match the dimensions of the second outer slider. Generally, the length of the second inner slider is greater than the length of the second outer slider, the width of the second inner slider is equal to the width of the second outer slider, and the height of the second inner slider is equal to the height of the second outer slider.

[0263] The dimensions of the second connecting block match the dimensions of the second inner slider. Generally, the length of the second connecting block is less than the length of the second inner slider, the width of the second connecting block is greater than the width of the second inner slider, and the height of the second connecting block is less than the height of the second inner slider.

[0264] In some of these embodiments, the fourth sliding element 151 is made of plastic.

[0265] In some of these embodiments, the fourth sliding element 151 is a second sliding block.

[0266] The first end of the second fixing element 152 is connected to the second inner slider.

[0267] The cross-section of the second fixing element 152 is rectangular.

[0268] The dimensions of the second fixing element 152 are matched with the dimensions of the fourth sliding element 151. Generally, the length of the second fixing element 152 is greater than the width of the second inner slider, the width of the second fixing element 152 is less than the length of the second inner slider, and the height of the second fixing element 152 is less than the height of the second inner slider.

[0269] The dimensions of the second fixing element 152 are matched with the dimensions of the first fixing element 142. Generally, the length of the second fixing element 152 is equal to the length of the first fixing element 142, the width of the second fixing element 152 is equal to the width of the first fixing element 142, and the height of the second fixing element 152 is equal to the height of the first fixing element 142.

[0270] In some embodiments, the second fixing element 152 is fixedly connected to the fourth sliding element 151. For example, the second fixing element 152 and the fourth sliding element 151 are integrally formed.

[0271] In some of these embodiments, the second fixing element 152 is made of plastic.

[0272] In some of these embodiments, the second fixing element 152 is a second fixing base.

[0273] The second bending adjustment element 153 is in contact with the guide wheel.

[0274] The cross-section of the second bending adjustment element 153 is circular.

[0275] The dimensions of the second bending adjustment element 153 are matched with the dimensions of the second fixing element 152. Generally, the diameter of the second bending adjustment element 153 is smaller than the length / height of the second fixing element 152.

[0276] The dimensions of the second bending adjustment element 153 are matched with the dimensions of the third receiving element 118. Generally, the diameter of the second bending adjustment element 153 is smaller than the diameter of the third receiving element 118, and the axial dimension of the second bending adjustment element 153 is larger than the axial dimension (e.g., depth) of the third receiving element 118.

[0277] The dimensions of the second bending adjustment element 153 are matched with the dimensions of the sixth receiving element 129. Generally, the diameter of the second bending adjustment element 153 is smaller than the diameter of the sixth receiving element 129, and the axial dimension of the second bending adjustment element 153 is larger than the axial dimension (e.g., depth) of the sixth receiving element 129.

[0278] The dimensions of the second bending adjustment element 153 are matched with the dimensions of the first bending adjustment element 143. Generally, the diameter of the second bending adjustment element 153 is equal to the diameter of the first bending adjustment element 143, and the axial dimension of the second bending adjustment element 153 is greater than the axial dimension of the first bending adjustment element 143.

[0279] The dimensions of the second bending adjustment element 153 are matched with the dimensions of the guide wheel. Generally, the diameter of the second bending adjustment element 153 is smaller than the diameter of the guide wheel.

[0280] In some of these embodiments, the second bending adjustment element 153 is fixedly connected to the fifth receiving element 128.

[0281] In some of these embodiments, the second bending adjustment element 153 is made of stainless steel.

[0282] In some of these embodiments, the second bending adjustment element 153 is a second linkage rod.

[0283] like Figure 10 As shown, the main electrode unit 160 includes a main electrode element 161 and a first signal transmission element 162. The main electrode element 161 is connected to the first end of the curved section of the catheter unit 120 and is used to determine whether the first end of the curved section of the catheter unit 120 is in close contact with the myocardium based on whether a damage current is detected by unipolar mapping. The first end of the first signal transmission element 162 is connected to the main electrode element 161, and the second end of the first signal transmission element 162 passes through the catheter unit 120 and the holding unit 110, and is connected to the three-dimensional positioning device for sending data to a remote control system.

[0284] Specifically, the main electrode element 161 is connected to the main electrode mounting element 122; the second end of the first signal transmission element 162 passes through the second main electrode placement element 1213, the first main electrode placement element 1212, and the two main electrode hole elements 116 in sequence.

[0285] The main electrode element 161 has a hollow structure at both ends. Specifically, the radial dimension of the main electrode element 161 increases from the first end to the second end. That is, the radial dimension of the main electrode element 161 increases from the first end to the second end of the bend section of the conduit element 121, which is used to adapt to the conduit element 121.

[0286] The dimensions of the main electrode element 161 are matched with the dimensions of the main electrode mounting element 122. Generally, the radial dimension (e.g., minimum inner edge, maximum inner edge) of the main electrode element 161 is equal to the radial dimension (e.g., minimum inner edge, maximum inner edge) of the main electrode mounting element 122, and the axial dimension of the main electrode element 161 is equal to the axial dimension of the main electrode mounting element 122.

[0287] The dimensions of the main electrode element 161 are matched with the dimensions of the conduit element 121. Generally, the radial dimension (such as the minimum outer edge and the maximum outer edge) of the main electrode element 161 is equal to the diameter of the conduit element 121, and the axial dimension of the main electrode element 161 is smaller than the axial dimension of the bend section of the conduit element 121.

[0288] In some of these embodiments, the main electrode element 161 is made of metal.

[0289] In some embodiments, the main electrode element 161 is fixedly connected to the main electrode mounting element 122, including but not limited to an embedded connection.

[0290] In some of these embodiments, the main electrode element 161 is the main metal electrode.

[0291] The cross-section of the first signal transmission element 162 is circular.

[0292] The dimensions of the first signal transmission element 162 are matched with the dimensions of the main electrode element 161. Generally, the diameter of the first signal transmission element 162 is smaller than the radial and axial dimensions of the main electrode element 161.

[0293] The dimensions of the first signal transmission element 162 are matched with the dimensions of the second main electrode placement element 1213 (the first main electrode placement element 1212 and the two main electrode hole elements 116). Generally, the diameter of the first signal transmission element 162 is smaller than the diameter of the second main electrode placement element 1213 (the first main electrode placement element 1212 and the two main electrode hole elements 116), and the axial dimension of the first signal transmission element 162 is larger than the axial dimension of the second main electrode placement element 1213 (the first main electrode placement element 1212 and the two main electrode hole elements 116).

[0294] In some embodiments, the first signal transmission element 162 is electrically connected to the main electrode element 161, including but not limited to solder joint connection.

[0295] In some of these embodiments, the first signal transmission element 162 is made of a metal material with an insulating layer on its surface.

[0296] In some of these embodiments, the first signal transmission element 162 is a main metal wire.

[0297] like Figure 11 As shown, the auxiliary electrode unit 170 includes an auxiliary electrode element 171 and a second signal transmission element 172. The auxiliary electrode element 171 is connected to the first end of the curved section of the catheter unit 120 and is used to cooperate with the main electrode unit 160 in mapping the position of the myocardium. The first end of the second signal transmission element 172 is connected to the auxiliary electrode element 171, and the second end of the second signal transmission element 172 passes through the catheter unit 120 and the holding unit 110 and is connected to the three-dimensional positioning device for sending data to a remote control system.

[0298] Specifically, the auxiliary electrode element 171 is connected to the auxiliary electrode mounting element 123; the second end of the second signal transmission element 172 passes through the second auxiliary electrode placement element 1211, the first auxiliary electrode placement element 1210, and the two auxiliary electrode hole elements 115 in sequence.

[0299] The number of auxiliary electrode units 170 matches the number of auxiliary electrode mounting elements 123. Generally, the number of auxiliary electrode units 170 is equal to the number of auxiliary electrode mounting elements 123.

[0300] The cross-section of the auxiliary electrode element 171 is annular.

[0301] The dimensions of the auxiliary electrode element 171 are matched with the dimensions of the auxiliary electrode mounting element 123. Generally, the radial dimension (e.g., inner edge, outer edge) of the auxiliary electrode element 171 is equal to the radial dimension (e.g., inner edge, outer edge) of the auxiliary electrode mounting element 123, and the axial dimension of the auxiliary electrode element 171 is equal to the axial dimension of the auxiliary electrode mounting element 123.

[0302] In some of these embodiments, the auxiliary electrode element 171 is made of metal.

[0303] In some embodiments, the auxiliary electrode element 171 is fixedly connected to the auxiliary electrode mounting element 123, including but not limited to an embedded connection.

[0304] In some of these embodiments, the auxiliary electrode element 171 is an auxiliary metal electrode.

[0305] The cross-section of the second signal transmission element 172 is circular.

[0306] The dimensions of the second signal transmission element 172 are matched with the dimensions of the auxiliary electrode element 171. Generally, the diameter of the second signal transmission element 172 is smaller than the radial and axial dimensions of the auxiliary electrode element 171.

[0307] The dimensions of the second signal transmission element 172 are matched with the dimensions of the second auxiliary electrode placement element 1211 (the first auxiliary electrode placement element 1210 and the two auxiliary electrode hole elements 115). Generally, the diameter of the second signal transmission element 172 is smaller than the diameter of the second auxiliary electrode placement element 1211 (the first auxiliary electrode placement element 1210 and the two auxiliary electrode hole elements 115), and the axial dimension of the second signal transmission element 172 is larger than the axial dimension of the second auxiliary electrode placement element 1211 (the first auxiliary electrode placement element 1210 and the two auxiliary electrode hole elements 115).

[0308] In some embodiments, the second signal transmission element 172 is electrically connected to the auxiliary electrode element 171, including but not limited to solder joint connection.

[0309] In some of these embodiments, the second signal transmission element 172 is made of a metal material with an insulating layer on its surface.

[0310] In some of these embodiments, the second signal transmission element 172 is an auxiliary metal wire.

[0311] like Figure 12a , Figure 12b As shown, the limiting unit 180 includes a base element 181, a first connecting element 182, a control element 183, and a limiting element 184. The base element 181 is disposed at the top of the holding unit 110 and communicates with the holding unit 110; the first connecting element 182 is disposed on the base element 181; the first end of the control element 183 is located inside the base element 181, and the second end of the control element 183 is located outside the base element 181 and rotatably connected to the first connecting element 182; the limiting element 184 is movably disposed inside the base element 181, connected to the first end of the control element 183, and abuts against the telescopic injection unit 190, used to fix the telescopic injection unit 190 under the action of the control element 183.

[0312] Specifically, the bottom end of the base element 181 is connected to the top end of the gripping element 111 and communicates with the first receiving element 112.

[0313] The base element 181 has a hollow top and hollow bottom structure.

[0314] The dimensions of the base element 181 are matched with the dimensions of the grip element 111. Generally, the outer length of the base element 181 is less than the outer length of the grip element 111, the outer width of the base element 181 is less than the outer width of the grip element 111, and the height of the base element 181 is less than the outer height of the grip element 111.

[0315] The dimensions of the base element 181 are matched with the dimensions of the first receiving element 112. Generally, the outer length of the base element 181 is equal to the length of the first receiving element 112, and the outer width of the base element 181 is equal to the width of the first receiving element 112.

[0316] In some embodiments, the base element 181 is fixedly connected to the gripping element 111. For example, the base element 181 and the gripping element 111 are integrally formed.

[0317] In some of these embodiments, the base element 181 is made of plastic.

[0318] In some of these embodiments, the base element 181 is a frame.

[0319] The cross-section of the first connecting element 182 is circular.

[0320] The dimensions of the first connecting element 182 are matched with the dimensions of the base element 181. Generally, the radial dimension of the first connecting element 182 is smaller than the outer length / outer height of the base element 181, and the axial dimension (such as depth) of the first connecting element 182 is equal to the inner wall thickness of the base element 181.

[0321] In some of these embodiments, the first connecting element 182 is a threaded hole.

[0322] The control element 183 includes a screw and a nut. Specifically, the screw is threadedly connected to the first connecting element 182, with the first end of the screw located inside the base element 181 and the second end of the screw located outside the base element 181; the nut is connected to the second end of the screw and is used to assist in twisting the screw to rotate it.

[0323] The dimensions of the screw are matched with the dimensions of the first connecting element 182. Generally, the diameter of the screw is equal to the diameter of the first connecting element 182, and the axial dimension of the screw is greater than the axial dimension (e.g., depth) of the first connecting element 182.

[0324] The size of the nut matches the size of the base element 181. Generally, the radial dimension of the nut is smaller than the outer length / outer height of the base element 181, and the axial dimension of the nut is smaller than the outer width of the base element 181.

[0325] The size of the nut is matched with the size of the screw. Generally, the radial dimension of the nut is larger than the diameter of the screw, and the axial dimension of the nut is smaller than the axial dimension of the screw.

[0326] In some of these embodiments, the control element 183 is made of plastic.

[0327] In some of these embodiments, the control element 183 is a bolt.

[0328] The limiting element 184 is connected to the first end of the screw.

[0329] The cross-section of the limiting element 184 is circular.

[0330] The dimensions of the limiting element 184 are matched with the dimensions of the screw. Generally, the diameter of the limiting element 184 is larger than the diameter of the screw, and the axial dimension of the limiting element 184 is smaller than the axial dimension of the screw.

[0331] The dimensions of the limiting element 184 are matched with the dimensions of the base element 181. Generally, the diameter of the limiting element 184 is smaller than the inner length / inner height of the base element 181, and the axial dimension of the limiting element 184 is smaller than the inner width of the base element 181.

[0332] In some embodiments, the limiting element 184 is fixedly connected to the control element 183, including but not limited to thermoforming welding.

[0333] In some of these embodiments, the limiting element 184 is made of plastic.

[0334] In some of these embodiments, the limiting element 184 is a locking plate.

[0335] like Figure 13a , Figure 13bAs shown, the active element 191, at least one fifth sliding element 192, a first injection element 193, a third rotating element 194, a fourth rotating element 195, a first transmission element 196, a second transmission element 197, a drive element 198, and a second injection element 199. The catheter unit 120 comprises a movable element 191 movably disposed inside the first end of the curved section; a fifth sliding element 192 connected to the first end of the movable element 191 and slidably connected to the first end of the curved section; a first injection element 193 communicating with the first end of the movable element 191 for in situ injection into the myocardium; a third rotating element 194 rotatably disposed inside the first end of the curved section; a fourth rotating element 195 rotatably disposed inside the first end of the curved section, the second end of the fourth rotating element 195 being connected to the first end of the third rotating element 194, and the first end of the fourth rotating element 195 being rotatably connected to the second end of the movable element 191, for rotating under the action of the third rotating element 194 to cause the movable element 191 to reciprocate along the axial direction of the catheter unit 120; and a first transmission element 196 rotatably disposed inside the first end of the curved section. The first end of the bend section is inside the tube and connected to the second end of the third rotating element 194; the second transmission element 197 is rotatably disposed inside the first end of the bend section of the conduit unit 120 and is connected to the first transmission element 196 for driving the first transmission element 196 to rotate; the drive element 198 is disposed inside the first end of the bend section of the conduit unit 120 and is connected to the first end of the bend section of the conduit unit 120 and the second transmission element 197 respectively for driving the second transmission element 197 to rotate; the first end of the second injection element 199 is connected to the second end of the movable element 191, and the second end of the second injection element 199 passes through the fourth rotating element 195, the third rotating element 194, the first transmission element 196, the conduit unit 120, the gripping unit 110, and the limiting unit 180 in sequence and is connected to the liquid supply device, and abuts against the limiting unit 180 for fixing under the action of the limiting unit 180.

[0336] Specifically, the movable element 191 is movably disposed on the fourth receiving element 125; the fifth sliding element 192 is slidably connected to the second sliding element 126; the first injection element 193 is movably disposed on the fourth receiving element 125; the third rotating element 194 is rotatably connected to the first rotating element 127; the fourth rotating element 195 is rotatably disposed on the fourth receiving element 125; the first transmission element 196 is rotatably disposed on the fourth receiving element 125; the second transmission element 197 is rotatably disposed on the fourth receiving element 125; the driving element 198 is disposed on the fourth receiving element 125 and connected to the conduit element 121; the second end of the second injection element 199 passes sequentially through the second injection hole element 124, the first injection hole element 114, the first receiving element 112, and the base element 181.

[0337] The cross-section of the active element 191 is annular.

[0338] The dimensions of the movable element 191 are matched with the dimensions of the fourth receiving element 125. Generally, the outer diameter of the movable element 191 is smaller than the diameter of the fourth receiving element 125, and the axial dimension of the movable element 191 is smaller than the axial dimension of the fourth receiving element 125.

[0339] In some of these embodiments, the active element 191 is made of plastic.

[0340] In some of these embodiments, the active element 191 is a threaded rod.

[0341] The fifth sliding element 192 has a rectangular cross-section.

[0342] The dimensions of the fifth sliding element 192 are matched with those of the movable element 191. Generally, the width / height of the fifth sliding element 192 is smaller than the inner diameter and axial dimension of the movable element 191, and the length of the fifth sliding element 192 is smaller than the outer diameter of the movable element 191.

[0343] The dimensions of the fifth sliding element 192 match those of the second sliding element 126. Generally, the length of the fifth sliding element 192 is greater than the width of the second sliding element 126, the width of the fifth sliding element 192 is less than the length of the second sliding element 126, and the height of the fifth sliding element 192 is equal to the height of the second sliding element 126.

[0344] The number of fifth sliding elements 192 matches the number of second sliding elements 126. Generally, the number of fifth sliding elements 192 is equal to the number of second sliding elements 126.

[0345] In some embodiments, the fifth sliding element 192 is fixedly connected to the movable element 191, including but not limited to a thermoplastic connection.

[0346] In some of these embodiments, the fifth sliding element 192 is made of plastic.

[0347] In some of these embodiments, the fifth sliding element 192 is the third sliding block.

[0348] The first injection element 193 has a hollow structure.

[0349] The cross-section of the first injection element 193 is circular.

[0350] The dimensions of the first injection element 193 are matched with the dimensions of the second injection hole element 124 (fourth receiving element 125). Generally, the outer diameter of the first injection element 193 is smaller than the diameter of the second injection hole element 124 (fourth receiving element 125), and the axial dimension of the first injection element 193 is smaller than the axial dimension of the second injection hole element 124 (fourth receiving element 125).

[0351] The axial dimension of the first injection element 193 is greater than the axial dimension of the portion of the second injection hole element 124 near the first end of the fourth receiving element 125.

[0352] The dimensions of the first injection element 193 are matched with the dimensions of the movable element 191. Generally, the inner diameter of the first injection element 193 is equal to the inner diameter of the movable element 191, the outer diameter of the first injection element 193 is smaller than the outer diameter of the movable element 191, and the axial dimension of the first injection element 193 is equal to the axial dimension of the movable element 191.

[0353] In some embodiments, the first injection element 193 is detachably connected to the movable element 191, including but not limited to a threaded connection. This detachable connection allows for the replacement of injection needles of different diameters.

[0354] In some of these embodiments, the first injection element 193 is made of stainless steel.

[0355] In some of these embodiments, the first injection element 193 is an injection needle.

[0356] The cross-section of the third rotating element 194 is annular.

[0357] The dimensions of the third rotating element 194 are matched with those of the first rotating element 127. Generally, the outer diameter of the third rotating element 194 is equal to the diameter of the first rotating element 127, and the axial dimension of the third rotating element 194 is equal to the axial dimension of the first rotating element 127.

[0358] In some of these embodiments, the third rotating element 194 is made of plastic.

[0359] In some of these embodiments, the third rotating element 194 is a rotating block.

[0360] The cross-section of the fourth rotating element 195 is annular.

[0361] The dimensions of the fourth rotating element 195 are matched with the dimensions of the fourth receiving element 125. Generally, the outer diameter of the fourth rotating element 195 is smaller than the diameter of the fourth receiving element 125, and the axial dimension of the fourth rotating element 195 is smaller than the axial dimension of the fourth receiving element 125.

[0362] The dimensions of the fourth rotating element 195 are matched with those of the third rotating element 194. Generally, the outer diameter of the fourth rotating element 195 is equal to the inner diameter of the third rotating element 194, and the axial dimension of the fourth rotating element 195 is greater than that of the third rotating element 194.

[0363] The dimensions of the fourth rotating element 195 are matched with those of the movable element 191. Generally, the inner diameter of the fourth rotating element 195 is equal to the outer diameter of the movable element 191, and the axial dimension of the fourth rotating element 195 is smaller than the axial dimension of the movable element 191.

[0364] In some embodiments, the fourth rotating element 195 is fixedly connected to the third rotating element 194, including but not limited to a thermoplastic connection.

[0365] In some of these embodiments, the fourth rotating element 195 is made of plastic.

[0366] In some of these embodiments, the fourth rotating element 195 is a threaded sleeve.

[0367] The cross-section of the first transmission element 196 is circular.

[0368] The dimensions of the first transmission element 196 are matched with the dimensions of the fourth receiving element 125. Generally, the outer diameter of the first transmission element 196 is smaller than the diameter of the fourth receiving element 125, and the axial dimension of the first transmission element 196 is smaller than the axial dimension of the fourth receiving element 125.

[0369] The dimensions of the first transmission element 196 are matched with the dimensions of the third rotating element 194. Generally, the outer diameter of the first transmission element 196 is smaller than the outer diameter of the third rotating element 194, the inner diameter of the first transmission element 196 is equal to the inner diameter of the third rotating element 194, and the axial dimension of the first transmission element 196 is smaller than the axial dimension of the third rotating element 194.

[0370] In some embodiments, the first transmission element 196 and the third rotation element 194 are fixedly connected, including but not limited to a thermoelectric connection.

[0371] In some of these embodiments, the first transmission element 196 is made of plastic.

[0372] In some of these embodiments, the first transmission element 196 is a first transmission gear.

[0373] The cross-section of the second transmission element 197 is circular.

[0374] The dimensions of the second transmission element 197 are matched with the dimensions of the fourth receiving element 125. Generally, the outer diameter of the second transmission element 197 is smaller than the diameter of the fourth receiving element 125, and the axial dimension of the second transmission element 197 is smaller than the axial dimension of the fourth receiving element 125.

[0375] The dimensions of the second transmission element 197 are matched with the dimensions of the first transmission element 196. Generally, the diameter of the second transmission element 197 is smaller than the outer diameter of the first transmission element 196, and the axial dimension of the second transmission element 197 is equal to the axial dimension of the first transmission element 196.

[0376] In some of these embodiments, the second transmission element 197 is made of plastic.

[0377] In some of these embodiments, the second transmission element 197 is a second transmission gear.

[0378] In some embodiments, the drive element 198 is fixedly connected to the conduit element 121, including but not limited to bolted connections.

[0379] In some embodiments, the drive element 198 is a servo motor. The drive element 198 is connected to a built-in movement and control switch to ensure sufficient power supply during operation.

[0380] The cross-section of the second injection element 199 is annular.

[0381] The dimensions of the second injection element 199 are matched with the dimensions of the movable element 191. Generally, the inner diameter of the second injection element 199 is not greater than the inner diameter of the movable element 191, the outer diameter of the second injection element 199 is smaller than the outer diameter of the movable element 191, and the axial dimension of the second injection element 199 is greater than the axial dimension of the movable element 191.

[0382] The dimensions of the second injection element 199 are matched with the dimensions of the fourth rotating element 195 (the third rotating element 194 and the first transmission element 196). Generally, the outer diameter of the second injection element 199 is smaller than the inner diameter of the fourth rotating element 195 (the third rotating element 194 and the first transmission element 196), and the axial dimension of the second injection element 199 is larger than the axial dimension of the fourth rotating element 195 (the third rotating element 194 and the first transmission element 196).

[0383] The dimensions of the second injection element 199 are matched with the dimensions of the second injection hole element 124 (the first injection hole element 114 and the first receiving element 112). Generally, the outer diameter of the second injection element 199 is smaller than the radial dimensions (such as diameter, length, and width) of the second injection hole element 124 (the first injection hole element 114 and the first receiving element 112), and the axial dimension of the second injection element 199 is larger than the axial dimension of the second injection hole element 124 (the first injection hole element 114 and the first receiving element 112).

[0384] The dimensions of the second injection element 199 are matched with the dimensions of the base element 181. Generally, the outer diameter of the second injection element 199 is smaller than the inner length / inner width of the base element 181, and the axial dimension of the second injection element 199 is larger than the height of the base element 181.

[0385] The axial dimension of the second injection element 199 is greater than the sum of the axial dimension of the second injection hole element 124, the axial dimension of the first injection hole element 114, the axial dimension (such as depth) of the first receiving element 112, and the height of the base element 181.

[0386] In some of these embodiments, the second injection element 199 is made of PVC.

[0387] In some embodiments, the second injection element 199 is a thin injection tube. The second injection element 199 is made of PVC material, which provides high toughness.

[0388] The method of using this invention is as follows:

[0389] (a) Catheter element 121 penetrates deep into the myocardium

[0390] The operator holds the syringe with the gripping element 111 and inserts the catheter element 121 into the myocardium.

[0391] (ii) Adjusting the position of catheter element 121

[0392] Pull the third sliding element 141 so that it slides along the first sliding element 113 away from the conduit element 121, and drive the first bending adjustment element 143 to bend the curved section of the conduit element 121 in the first direction through the first fixing element 142.

[0393] Pull the fourth sliding element 151 so that it slides along the first sliding element 113 toward the direction of the conduit element 121, and drive the second bending adjustment element 153 along the second rotating element 131 to bend the curved section of the conduit element 121 in the second direction through the second fixing element 152;

[0394] During the process, the auxiliary electrode element 171 can map the signal of the local myocardium. The auxiliary electrode element 171 becomes the proximal electrode for electrophysiological mapping, forming a pair of mapping electrodes with the distal electrode.

[0395] When the number of auxiliary electrode elements 171 is greater than 1, multiple pairs of calibration electrodes can be formed, and multiple pairs of calibration electrodes can expand the calibration range.

[0396] (III) Injection Procedure

[0397] Connect the liquid supply device to the second injection element 199;

[0398] The limiting element 184 is moved along the base element 181 by the control element 183, so that the limiting element 184 is separated from the second injection element 199.

[0399] The drive element 198 operates, causing it to drive the first transmission element 196 to rotate via the second transmission element 197;

[0400] The first transmission element 196 drives the fourth rotation element 195 to rotate radially along the first rotation element 127 via the third rotation element 194;

[0401] The fourth rotating element 195 drives the movable element 191 to move along the second sliding element 126 toward the first end of the catheter element 121 until the first injection element 193 is moved out of the catheter element 121 to perform the injection operation.

[0402] During the process, the main electrode element 161 is used as a monopolar electrode for mapping, so that the presence of damage current in the monopolar mapping can be used to determine whether the first end (tip) of the catheter element 121 is in close contact with the myocardium.

[0403] The main electrode element 161 and the auxiliary electrode element 171 form a pair of electrodes for bipolar mapping, which enables the voltage mapping of bipolar mapping to determine the location of the diseased myocardium.

[0404] The advantages of this invention are as follows: the relative curvature of the curved section of the catheter unit can be adjusted using the first and second bending adjustment units to better suit the structure of the myocardium; the potential between the main electrode unit and the auxiliary electrode unit can be used to mark the myocardial location of the first end of the catheter unit and determine whether the telescopic injection unit is in close contact with the heart, further improving its suitability for the myocardial structure; the telescopic injection unit can assist in advancing the injection needle, avoiding the instability of manual advancement and improving injection stability; and the limiting unit can stabilize the injection tubing of the telescopic injection unit, further improving stability.

[0405] Example 2

[0406] This embodiment relates to the in-situ injection system of the present invention.

[0407] like Figure 14 As shown, a multifunctional myocardial in situ injection system includes a multifunctional myocardial in situ injection device 100, a three-dimensional positioning device 200, and a fluid supply device 300 as described in Example 1. The three-dimensional positioning device 200 is connected to the main electrode unit 160 and the auxiliary electrode unit 170 of the multifunctional myocardial in situ injection device 100, and is used to determine whether the first end of the curved section of the catheter unit 120 is in close contact with the myocardium and to determine the location of the mapped myocardium. The fluid supply device 300 is connected to the telescopic injection unit 190 of the multifunctional myocardial in situ injection device 100, and is used to deliver injection fluid to the telescopic injection unit 190.

[0408] Specifically, the three-dimensional positioning device 200 is connected to the first signal transmission element 162 and the second signal transmission element 172; the liquid supply device 300 is connected to the second injection element 199.

[0409] In some of these embodiments, the three-dimensional positioning device 200 is an electrophysiological mapping / three-dimensional positioning device.

[0410] In some of these embodiments, the liquid supply device 300 is a syringe or a micropump.

[0411] The method of using this invention is as follows:

[0412] (I) Data Transmission

[0413] The three-dimensional positioning device 200 is connected to the first signal transmission element 162 and the second signal transmission element 172, and performs corresponding data transmission.

[0414] (II) Injection Procedure

[0415] The liquid supply device 300 is connected to the second injection element 199 and delivers the injection liquid.

[0416] The advantage of this invention is that it transmits relevant data to the three-dimensional positioning device through the main electrode unit and the auxiliary electrode unit, thereby enabling real-time monitoring of the position of the multifunctional myocardial in situ injection device within the myocardium.

[0417] The above description is merely a preferred embodiment of the present invention and does not limit the implementation and protection scope of the present invention. Those skilled in the art should realize that any equivalent substitutions and obvious changes made based on the description and illustrations of the present invention should be included within the protection scope of the present invention.

Claims

1. A multifunctional in situ myocardial injection device, characterized in that, include: A grip unit (110) for use by a user; The catheter unit (120) includes a curved section and a straight section, the second end of the curved section is connected to the first end of the straight section, and the second end of the straight section of the catheter unit (120) is connected to the first end of the holding unit (110). A rotating unit (130) is rotatably disposed inside the gripping unit (110); A first bending adjustment unit (140) is provided, with its first end connected to the second end of the curved section of the catheter unit (120), and its second end slidably connected to the gripping unit (110), for driving the curved section of the catheter unit (120) to bend in the first direction. The second bending adjustment unit (150) has a first end connected to the second end of the curved section of the catheter unit (120), and the second end of the second bending adjustment unit (150) passes around the rotating unit (130) and is slidably connected to the holding unit (110) to drive the curved section of the catheter unit (120) to bend in a second direction, wherein the second direction is opposite to the first direction; The main electrode unit (160) has its first end connected to the first end of the curved section of the catheter unit (120), and its second end passes through the catheter unit (120) and the holding unit (110) and is connected to the three-dimensional positioning device. It is used to determine whether the first end of the curved section of the catheter unit (120) is in close contact with the myocardium based on whether a damage current appears in the monopolar mapping and to send data to the remote control system. At least one auxiliary electrode unit (170) is provided, the first end of which is connected to the first end of the curved section of the catheter unit (120), and the second end of which passes through the catheter unit (120) and the gripping unit (110) and is connected to a three-dimensional positioning device, for use in conjunction with the main electrode unit (160) to map the position of the myocardium and to send data to the remote control system; A limiting unit (180) is disposed at the top of the gripping unit (110) and communicates with the gripping unit (110); A telescopic injection unit (190) is provided, the first end of which is internally connected to the first end of the curved section of the catheter unit (120), and the second end of which passes through the catheter unit (120), the gripping unit (110), and the limiting unit (180) and communicates with the liquid supply device and abuts against the limiting unit (180), for in situ injection of myocardium and fixation under the action of the limiting unit (180).

2. The multifunctional myocardial in situ injection device according to claim 1, characterized in that, The gripping unit (110) includes: A gripping element (111) is provided, the first end of which is connected to the second end of the straight tube section of the conduit unit (120), the top end of which is connected to the bottom end of the limiting unit (180), and the interior of which is rotatably connected to the rotating unit (130) for use by the user. A first receiving element (112) is disposed at the top of the gripping element (111) and communicates with the limiting unit (180) for the telescopic injection unit (190) to pass through the gripping element (111); The first sliding element (113) is disposed at the front end of the gripping element (111) and is slidably connected to the first bending adjustment unit (140) and the second bending adjustment unit (150) respectively. A first injection hole element (114) is disposed at the first end of the gripping element (111) and communicates with the catheter unit (120) for the telescopic injection unit (190) to pass through the gripping element (111). Two auxiliary electrode hole elements (115) are respectively disposed at the first end and the second end of the gripping element (111), and are located above the first sliding element (113), and communicate with the conduit unit (120) for the auxiliary electrode unit (170) to pass through the gripping element (111). Two main electrode hole elements (116) are respectively disposed at the first end and the second end of the gripping element (111), and are located below the first sliding element (113), and communicate with the conduit unit (120) for the main electrode unit (160) to pass through the gripping element (111). The second receiving element (117) is disposed at the first end of the gripping element (111) and located above the auxiliary electrode hole element (115), and communicates with the conduit unit (120) for the first bending adjustment unit (140) to pass through the gripping element (111). A third receiving element (118) is disposed at the first end of the gripping element (111) and located below the main electrode hole element (116), and communicates with the conduit unit (120) for the second bending adjustment unit (150) to pass through the gripping element (111).

3. The multifunctional myocardial in situ injection device according to claim 1, characterized in that, The catheter unit (120) includes: The catheter element (121) includes a curved section and a straight section, the second end of the curved section is connected to the first end of the straight section, and the second end of the straight section of the catheter element (121) is connected to the first end of the gripping unit (110). A main electrode mounting element (122) is disposed at the first end of the bend section of the conduit element (121) and connected to the main electrode unit (160); At least one auxiliary electrode mounting element (123) is disposed at the first end of the bend section of the conduit element (121) and connected to the auxiliary electrode unit (170); A second injection hole element (124) is disposed through the catheter element (121) and communicates with the gripping unit (110) for the telescopic injection unit (190) to pass through the catheter element (121). The fourth receiving element (125) is disposed at the first end of the bend section of the conduit element (121), and communicates with the second injection hole element (124) and is connected to the telescopic injection unit (190) for placing the telescopic injection unit (190). At least one second sliding element (126) is disposed at the first end of the bend section of the conduit element (121); and communicates with the fourth receiving element (125) and is slidably connected to the telescopic injection unit (190); The first rotating element (127) is disposed at the first end of the bend section of the conduit element (121); and is connected to the fourth receiving element (125) and rotatably connected to the telescopic injection unit (190); The fifth receiving element (128) is disposed at the second end of the straight section of the conduit element (121), and communicates with the gripping unit (110) and is connected to the first end of the first bending adjustment unit (140) for the first bending adjustment unit (140) to pass through the conduit element (121). The sixth receiving element (129) is disposed at the second end of the straight section of the conduit element (121), communicates with the gripping unit (110), and is connected to the first end of the second bending adjustment unit (150) for the second bending adjustment unit (150) to pass through the conduit element (121). A first auxiliary electrode placement element (1210) is disposed at the first end of the straight tube section of the conduit element (121) and communicates with the gripping unit (110); At least one second auxiliary electrode placement element (1211) is disposed inside the conduit element (121) and communicates with the auxiliary electrode mounting element (123) and the first auxiliary electrode placement element (1210) respectively, for cooperating with the first auxiliary electrode placement element (1210) to pass the auxiliary electrode unit (170) through the conduit element (121); The first main electrode placement element (1212) is disposed at the first end of the straight tube section of the conduit element (121) and communicates with the gripping unit (110); At least one second main electrode placement element (1213) is disposed inside the conduit element (121) and communicates with the main electrode mounting element (122) and the first main electrode placement element (1212) respectively, for cooperating with the first main electrode placement element (1212) to pass the main electrode unit (160) through the conduit element (121).

4. The multifunctional myocardial in situ injection device according to claim 1, characterized in that, The rotating unit (130) includes: The second rotating element (131) is rotatably disposed inside the gripping unit (110) and contacts the second bending adjustment unit (150); An anti-detachment element (132) is provided, the end of which is connected to the second rotating element (131) to prevent the second bending adjustment unit (150) from detaching from the second rotating element (131).

5. The multifunctional myocardial in situ injection device according to claim 1, characterized in that, The first bending adjustment unit (140) includes: A third sliding element (141) is slidably connected to the gripping unit (110); A first fixing element (142) is connected at its first end to the third sliding element (141) for reciprocating along the axial direction of the gripping unit (110) under the action of the third sliding element (141). The first bending adjustment element (143) has its first end connected to the conduit unit (120) and its second end connected to the second end of the first fixing element (142), and is used to drive the curved section of the conduit unit (120) to bend in the first direction under the action of the third sliding element (141).

6. The multifunctional myocardial in situ injection device according to claim 1, characterized in that, The second bending adjustment unit (150) includes: A fourth sliding element (151) is slidably connected to the gripping unit (110); The second fixing element (152) has its first end connected to the fourth sliding element (151) and is used to reciprocate along the axial direction of the gripping unit (110) under the action of the fourth sliding element (151). The second bending adjustment element (153) has its first end bypassing the rotating unit (130) and connected to the conduit unit (120), and its second end connected to the second end of the second fixing element (152), for driving the curved section of the conduit unit (120) to bend in the second direction under the action of the fourth sliding element (151).

7. The multifunctional myocardial in situ injection device according to claim 1, characterized in that, The main electrode unit (160) includes: The main electrode element (161) is connected to the first end of the curved section of the catheter unit (120) and is used to determine whether the first end of the curved section of the catheter unit (120) is in close contact with the myocardium based on whether a damage current appears in the unipolar mapping. A first signal transmission element (162) has a first end connected to the main electrode element (161), and a second end passing through the conduit unit (120) and the gripping unit (110) and connected to the three-dimensional positioning device, for transmitting data to a remote control system; and / or The auxiliary electrode unit (170) includes: An auxiliary electrode element (171) is connected to the first end of the curved section of the catheter unit (120) and is used to cooperate with the main electrode unit (160) to map the position of the myocardium. The second signal transmission element (172) has its first end connected to the auxiliary electrode element (171) and its second end passing through the conduit unit (120) and the gripping unit (110) and connected to the three-dimensional positioning device, for sending data to the remote control system.

8. The multifunctional myocardial in situ injection device according to claim 1, characterized in that, The limiting unit (180) includes: A base element (181) is disposed at the top of the gripping unit (110) and communicates with the gripping unit (110); A first connecting element (182) is disposed on the base element (181); A control element (183) has a first end located inside the base element (181) and a second end located outside the base element (181), and is rotatably connected to the first connecting element (182). A limiting element (184) is movably disposed inside the base element (181) and connected to the first end of the control element (183), and abuts against the telescopic injection unit (190), for fixing the telescopic injection unit (190) under the action of the control element (183).

9. The multifunctional myocardial in situ injection device according to claim 1, characterized in that, The telescopic injection unit (190) includes: Movable element (191), which is movably disposed inside the first end of the bend section of the conduit unit (120); At least one fifth sliding element (192) is disposed at the first end of the movable element (191) and is slidably connected to the first end of the bend section of the conduit unit (120); A first injection element (193) is connected to the first end of the active element (191) and is used for in situ injection into the myocardium; A third rotating element (194) is rotatably disposed inside the first end of the bend section of the conduit unit (120); A fourth rotating element (195) is rotatably disposed inside the first end of the bend section of the conduit unit (120). The second end of the fourth rotating element (195) is connected to the first end of the third rotating element (194). The first end of the fourth rotating element (195) is rotatably connected to the second end of the movable element (191). The fourth rotating element (195) is used to rotate under the action of the third rotating element (194) so ​​that the movable element (191) reciprocates along the axial direction of the conduit unit (120). The first transmission element (196) is rotatably disposed inside the first end of the bend section of the conduit unit (120) and connected to the second end of the third rotating element (194); The second transmission element (197) is rotatably disposed inside the first end of the bend section of the conduit unit (120) and is connected to the first transmission element (196) for driving the first transmission element (196) to rotate. A driving element (198) is disposed inside the first end of the bend section of the conduit unit (120) and is connected to the first end of the bend section of the conduit unit (120) and the second transmission element (197) respectively, for driving the second transmission element (197) to rotate; The second injection element (199) has its first end connected to the second end of the movable element (191). The second end of the second injection element (199) passes through the fourth rotating element (195), the third rotating element (194), the first transmission element (196), the conduit unit (120), the gripping unit (110), and the limiting unit (180) and is connected to the liquid supply device, and abuts against the limiting unit (180) for fixing under the action of the limiting unit (180).

10. A multifunctional in situ myocardial injection system, characterized in that, include: The multifunctional myocardial in situ injection device (100) as described in any one of claims 1 to 9; A three-dimensional positioning device (200) is connected to the main electrode unit (160) and the auxiliary electrode unit (170) of the multifunctional myocardial in situ injection device (100) to obtain whether the first end of the curved section of the catheter unit (120) is in close contact with the myocardium and to obtain the position of the mapped myocardium. A liquid supply device (300) is connected to the telescopic injection unit (190) of the multifunctional myocardial in situ injection device (100) and is used to supply injection solution to the telescopic injection unit (190).

Images