Clinical pharmaceutical medicament preparation equipment

Abstract

The invention relates to the technical field of medicament preparation equipment, in particular to clinical pharmaceutical medicament preparation equipment which comprises a hollow circular-truncated-cone-shaped base and a tank with two open end faces, the tank is vertically and fixedly connected to the top of the base, the bottom end of the interior of the tank is rotationally connected with a rotating pipe through a rotating structure, the rotating pipe is round outside and square inside, and the top end of the rotating pipe is fixedly connected with a lug. An annular rotating ring is rotatably mounted at the top end of the interior of the tank body, a connecting plate is fixedly connected to the bottom surface of the rotating ring, a plurality of shearing and stirring structures which are hinged to one another are arranged between lugs and the connecting plate, and each shearing and stirring structure comprises two rotating blocks. And in the stirring process, the shearing tool is driven by the stirring blades to be opened and closed, so that the raw materials which regularly rotate in the tank body are cut off, and an isolation layer formed by covering the surface of the pasty medicament with the powdery medicament is broken.

Description

Technical Field

[0001] This invention relates to the field of pharmaceutical preparation equipment technology, and more particularly to a clinical pharmaceutical preparation equipment. Background Technology

[0002] Pharmaceutics is a comprehensive applied technology discipline that studies the theory of drug preparation, production technology, and quality control. It is a discipline that combines the principles and techniques of prescription preparation and formulation preparation because they are largely similar. In the process of drug preparation, multiple drugs need to be mixed. Currently, the common method is to manually shake the container holding the drugs. While this method is more effective for preparing liquid drugs, it is prone to uneven mixing when preparing powdered drugs or drugs based on pastes, resulting in suboptimal final drug efficacy.

[0003] To address the aforementioned issues, existing technologies incorporate stirring equipment within the container of the prepared medication for mixing. However, while these stirring devices are effective for mixing powdered drugs, they present the following problems when dealing with medications based on pastes:

[0004] like Figure 1 As shown, during drug preparation, the paste-like drug is first added to the container as a base, followed by other powdered drugs. The powdered drugs are then placed on top of the paste. The paste rotates within the container under the action of a stirring device. During this rotation, the paste may take the form of a cylinder with an internal conical cavity due to centrifugal force and gravity. The powdered drugs, under the influence of gravity, centrifugal force, and airflow within the container, disperse within the conical cavity and spread onto its walls. This layer of powdered drugs forms a barrier on the cavity walls, preventing other powdered drugs from contacting the paste. Only after the powdered drugs on the cavity walls dissolve into the paste can the other powdered drugs come into contact and mix. This process takes a considerable amount of time, prolonging drug preparation and failing to meet the timeliness requirements of clinical drug use. Summary of the Invention

[0005] The purpose of this invention is to address the drawback of time-consuming drug preparation methods based on ointment-like preparations in existing technologies, and to propose a clinical pharmaceutical preparation device.

[0006] To achieve the above objectives, the present invention adopts the following technical solution:

[0007] Design a clinical pharmaceutical preparation device, including a hollow frustum-shaped base and a tank with open ends. The tank is vertically fixed to the top of the base. The bottom of the tank is rotatably connected to a rotating tube with an outer circle and an inner square shape via a rotating structure. The top of the rotating tube is fixedly connected to an ear plate. A circular rotating ring is rotatably installed at the top of the tank. A connecting plate is fixedly connected to the bottom of the rotating ring. Multiple shearing and stirring structures are provided between the ear plate and the connecting plate. The shearing and stirring structure includes two rotating blocks that are rotatably connected together. Each rotating block has a stirring blade and a shearing blade fixedly connected to its outer wall. The stirring blade at the top is hinged to the connecting plate, and the stirring blade at the bottom is hinged to the ear plate.

[0008] Preferably, the rotating structure includes an annular piston component, which is slidably fitted inside the tank body, and a baffle is rotatably installed inside the piston component, with the rotating tube rotatably installed in the middle of the baffle.

[0009] Preferably, the base has a drive structure inside for driving the rotating tube to rotate. The drive structure includes a motor and a square rotating rod. The motor is fixed inside the base, and the rotating rod is fixed to the output shaft of the motor. The rotating rod is slidably fitted inside the rotating tube.

[0010] Preferably, the base is provided with a limiting structure to restrict the rotation of the baffle. The limiting structure includes a slider. A sliding hole is vertically opened in the base. The slider is slidably fitted in the sliding hole. A tension spring is provided at the bottom of the sliding hole. The top of the tension spring is fixed to the slider. An extension rod is vertically fixed to the top of the slider. The bottom surface of the extension rod is fixed to the lower end surface of the baffle.

[0011] Preferably, the tension spring always applies a downward pulling force to the slider.

[0012] Preferably, a central gear is fixedly connected to the bottom of the rotating tube, a ring gear is fixedly connected to the bottom surface of the piston, and a transmission gear is rotatably mounted on the bottom surface of the baffle. The ring gear, the transmission gear, and the central gear are matched so that when the central gear rotates, the ring gear is driven to rotate in the opposite direction through the transmission gear.

[0013] Preferably, a pipe is fixedly connected inside the base, and a wavy guide groove is formed on the inner wall of the pipe. An L-shaped guide rod is fixedly connected to the lower end face of the ring gear, and the guide rod is slidably engaged in the guide groove.

[0014] Preferably, the top of the tank is provided with a threaded portion, and an end cap is threaded onto the threaded portion to seal the top of the tank.

[0015] Preferably, the outer wall of the end cap is provided with anti-slip texture to increase the coefficient of friction.

[0016] Preferably, the piston component has a flow channel inside, a circular sealing ring is fixedly connected to the top of the piston component, a plurality of blade-shaped cutting blocks are fixedly connected to the upper surface of the sealing ring, a plurality of through holes are opened on the sealing ring for accommodating the fluid agent in the tank to enter the flow channel, and a plurality of discharge pipes are fixedly connected to the inner ring of the piston component at an incline. The discharge pipes are connected to the flow channel to accommodate the discharge of the agent in the flow channel.

[0017] The clinical pharmaceutical preparation device proposed in this invention has the following advantages: When preparing the preparation, the device mixes and stirs the raw materials by rotating the stirring blades in the tank. During the stirring process, the stirring blades drive the shearing blades to open and close, thereby cutting and segmenting the raw materials that are rotating regularly in the tank, breaking the barrier layer formed by the powdered drug on the surface of the paste drug. Attached Figure Description

[0018] Figure 1 This is a schematic diagram illustrating the preparation process of a paste-based medicine using existing technology.

[0019] Figure 2 This is a schematic diagram of the structure of a clinical pharmaceutical preparation device proposed in this invention.

[0020] Figure 3 This is a schematic diagram of the internal structure of the tank and base of a clinical pharmaceutical preparation device proposed in this invention.

[0021] Figure 4 This invention provides a clinical pharmaceutical preparation device. Figure 3 The main view.

[0022] Figure 5 This is a schematic diagram of the internal structure of the tubing in a clinical pharmaceutical preparation device proposed in this invention.

[0023] Figure 6 This is a schematic diagram of the bottom of the tank of a clinical pharmaceutical preparation device proposed in this invention.

[0024] Figure 7 This is a schematic diagram of the internal structure of the tank of a clinical pharmaceutical preparation device proposed in this invention.

[0025] Figure 8 This invention provides a clinical pharmaceutical preparation device. Figure 7 Enlarged view of point A in the middle.

[0026] Figure 9 This is a schematic diagram of the installation structure of the stirring blade and shearing blade of a clinical pharmaceutical preparation device proposed in this invention.

[0027] Figure 10This is a schematic diagram of the piston component of a clinical pharmaceutical preparation device proposed in this invention.

[0028] Figure 11 This invention provides a clinical pharmaceutical preparation device. Figure 10 Enlarged view of section B in the middle.

[0029] In the diagram: 1. Base; 2. Tank body; 3. Threaded part; 4. End cap; 5. Rotating ring; 6. Connecting plate; 7. Stirring blade; 8. Rotating block; 9. Shearing blade; 10. Ear plate; 11. Rotating tube; 12. Piston; 13. Ring gear; 14. Transmission gear; 15. Central gear; 16. Flow channel; 17. Discharge pipe; 18. Sealing ring; 19. Cutting block; 20. Through hole; 21. Pipe fitting; 22. Guide groove; 23. Guide rod; 24. Extension rod; 25. Slider; 26. Motor; 27. Rotating rod; 28. Sliding hole; 29. ​​Tension spring; 30. Baffle. Detailed Implementation

[0030] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments.

[0031] Reference Figures 2-4 A clinical pharmaceutical preparation device includes a hollow frustum-shaped base 1 and a can 2 with open ends. The can 2 is vertically fixed to the top of the base 1. The top of the can 2 is provided with a threaded part 3, and an end cap 4 is threaded onto the threaded part 3 to seal the top of the can 2. The outer wall of the end cap 4 is provided with anti-slip texture to increase the coefficient of friction.

[0032] The container 2 is used to hold the raw materials for preparing the medicine. The end cap 4 is threaded into the threaded part 3, and the medicine preparer can manually turn it to open or close the container 2.

[0033] like Figures 4-7 and Figure 9 As shown, the bottom of the tank body 2 is rotatably connected to a rotating tube 11 with an outer circle and an inner square through a rotating structure. The top of the rotating tube 11 is fixedly connected to an ear plate 10. A circular rotating ring 5 is rotatably installed at the top of the tank body 2. A connecting plate 6 is fixedly connected to the bottom surface of the rotating ring 5. Multiple shearing and stirring structures are provided between the ear plate 10 and the connecting plate 6. The shearing and stirring structure includes two rotating blocks 8, which are rotatably connected together. Each rotating block 8 has a stirring blade 7 and a shearing blade 9 fixedly connected to its outer wall. The stirring blade 7 at the top is hinged to the connecting plate 6, and the stirring blade 7 at the bottom is hinged to the ear plate 10.

[0034] When the rotating tube 11 rotates, it drives multiple hinged stirring blades 7 to revolve within the tank 2 to stir and mix the pharmaceutical raw materials.

[0035] When the rotating tube 11 moves up and down inside the tank 2, it drives the shearing blade 9 to open and close through the stirring blade 7. During the opening and closing process, the shearing blade 9 can not only push the agent to move vertically in the tank 2 so that the upper and lower layers of the agent raw materials are mixed, but also shear the raw materials in the tank to cut and divide the regularly rotating raw materials in the tank 2, breaking the isolation layer formed by the powdered agent.

[0036] like Figures 4-8 As shown, the rotating structure includes an annular piston 12, which is slidably fitted inside the tank 2. A baffle 30 is rotatably installed inside the piston 12. The rotating tube 11 is rotatably installed in the middle of the baffle 30. The base 1 is provided with a driving structure to drive the rotating tube 11 to rotate. The driving structure includes a motor 26 and a square rotating rod 27. The motor 26 is fixed inside the base 1, and the rotating rod 27 is fixed to the output shaft of the motor 26. The rotating rod 27 is slidably fitted inside the rotating tube 11.

[0037] When the motor 26 is powered on, it drives the rotating tube 11 to rotate through the rotating rod 27 on the output shaft. The rotating rod 27 is in sliding engagement with the rotating tube 11. Therefore, the rotating rod 27 will not affect the vertical movement of the rotating tube 11 while driving the rotating tube 11 to rotate.

[0038] The piston 12 is shaped to match the internal shape of the tank 2. When the piston 12 moves vertically, it applies a vertical force to the outer ring of the paste, thereby pushing the bottom and top of the paste to mix, accelerating the stirring process and reducing the time required for the material to be mixed evenly.

[0039] like Figure 10 and Figure 11 As shown, the piston 12 has a flow channel 16 inside, and a circular sealing ring 18 is fixed to the top of the piston 12. Multiple blade-shaped cutting blocks 19 are fixed to the upper surface of the sealing ring 18. Multiple through holes 20 are opened on the sealing ring 18 to accommodate the fluid agent in the tank 2 entering the flow channel 16. Multiple discharge pipes 17 are fixed to the inner ring of the piston 12 at an incline. The discharge pipes 17 are connected to the flow channel 16 to accommodate the discharge of the agent in the flow channel 16.

[0040] During the stirring and rotation process, the paste-like medicine at the bottom is squeezed into the flow channel 16 under the action of gravity and centrifugal force. Before entering the flow channel 16, the paste-like medicine is divided by the cutting block 19 and the through hole 20, thereby breaking up the paste-like medicine that is stuck together and making it into fragments. The fragmented paste-like medicine in the flow channel 16 is discharged through the discharge pipe 17 under the pressure of the external paste-like medicine, so that the fragmented paste-like medicine comes into contact with the powder-like medicine in the middle of the tank 2, thereby increasing the contact area between the powder-like medicine and the paste-like medicine, further improving the mixing efficiency and saving stirring time.

[0041] like Figure 3 and Figure 4 As shown, the base 1 is provided with a limiting structure to restrict the rotation of the baffle 30. The limiting structure includes a slider 25. A sliding hole 28 is vertically opened in the base 1. The slider 25 is slidably fitted in the sliding hole 28. A tension spring 29 is provided at the bottom of the sliding hole 28. The top of the tension spring 29 is fixed to the slider 25. The tension spring 29 always applies a downward pulling force to the slider 25. An extension rod 24 is vertically fixed to the top of the slider 25. The bottom surface of the extension rod 24 is fixed to the lower end surface of the baffle 30.

[0042] During the rotation of the rotating tube 11, the slider 25 is located inside the sliding hole 28. The extension rod 24 connects the baffle 30 and the slider 25 into one unit. The limiting of the slider 25 by the sliding hole 28 can prevent the baffle 30 from rotating together with the rotating tube 11, and does not affect the lifting and lowering action of the baffle 30.

[0043] like Figures 4-7 As shown, a central gear 15 is fixedly connected to the bottom of the rotating tube 11, a ring gear 13 is fixedly connected to the bottom surface of the piston 12, and a transmission gear 14 is rotatably mounted on the bottom surface of the baffle 30. The ring gear 13, the transmission gear 14 and the central gear 15 are matched so that when the central gear 15 rotates, the ring gear 13 is driven to rotate in the opposite direction through the transmission gear 14. A pipe 21 is fixedly connected inside the base 1. A wave-shaped guide groove 22 is opened on the inner wall of the pipe 21. An L-shaped guide rod 23 is fixedly connected to the lower end face of the ring gear 13. The guide rod 23 slides in the guide groove 22.

[0044] When the rotating tube 11 rotates, it drives the central gear 15 to rotate synchronously. The central gear 15 drives the ring gear 13 to rotate in the opposite direction through the transmission gear 14. During the rotation of the ring gear 13, it drives the L-shaped guide rod 23 to rotate synchronously. Since the guide rod 23 cooperates with the wave-shaped guide groove 22, the guide rod 23 is driven by the guide groove 22 to rise and fall during rotation, so that the piston 12 continuously performs linear reciprocating motion in the vertical direction in the tank 2, so as to repeatedly push the bottom and top of the paste medicine to mix.

[0045] Working principle:

[0046] When performing clinical drug preparation:

[0047] The pharmacist will manually open end cap 4, first add the paste-like medicine base into container 2, and then add the powdered medicine into container 2;

[0048] The motor 26 is started, which drives the rotating rod 27 to rotate. The rotating rod 27 drives the rotating tube 11 to rotate, and the rotating tube 11 rotates, causing the ear plate 10 to rotate. During the rotation of the ear plate 10, the stirring blade 7 rotates inside the tank 2. While the stirring blade 7 is rotating, it also mixes the various drug raw materials. During the stirring process, the paste medicine will form a mixture like... Figure 1 The state shown;

[0049] During the rotation of the rotating tube 11, the central gear 15 is driven to rotate. The central gear 15 drives the ring gear 13 to rotate in the opposite direction through the transmission gear 14. The reverse rotation of the ring gear 13 drives the piston 12 to rotate in the opposite direction. The piston 12 drives the sealing ring 18 to rotate in the opposite direction. The cutting block 19 on the upper surface of the sealing ring 18 applies a force to the paste from the bottom in the opposite direction of its rotation, thereby causing the paste to tear and break under the action of two opposite forces, so as to increase the contact area between the paste base and the powdered medicine.

[0050] During the stirring and rotation process, the paste-like medicine at the bottom is squeezed into the flow channel 16 under the action of gravity and centrifugal force. Before entering the flow channel 16, the paste-like medicine is divided by the cutting block 19 and the through hole 20, thereby breaking up the sticky paste-like medicine into fragments. The fragmented paste-like medicine in the flow channel 16 is discharged through the discharge pipe 17 under the pressure of the external paste-like medicine, so that the fragmented paste-like medicine comes into contact with the powder-like medicine in the middle of the tank 2, thereby increasing the contact area between the powder-like medicine and the paste-like medicine, further improving the mixing efficiency and saving stirring time.

[0051] During the rotation of the ring gear 13, the L-shaped guide rod 23 will rotate synchronously. Since the guide rod 23 cooperates with the wave-shaped guide groove 22, the guide rod 23 will be driven by the guide groove 22 to rise and fall during rotation, so that the piston 12 will continuously perform linear reciprocating motion in the vertical direction in the tank 2, so as to repeatedly push the bottom and top of the paste medicine to mix.

[0052] During the vertical reciprocating motion of the piston 12, the shearing blade 9 is driven to open and close by the stirring blade 7. During the opening and closing process, the shearing blade 9 can not only push the agent to move vertically in the tank 2 to mix the upper and lower layers of the agent raw materials, but also shear the raw materials in the tank to cut and divide the regularly rotating raw materials in the tank 2, breaking the isolation layer formed by the powdered agent.

[0053] Compared with the prior art, the clinical pharmaceutical preparation equipment provided in this application mixes and stirs the raw materials by rotating the stirring blades 7 in the tank 2 during preparation. During the stirring process, the stirring blades 7 drive the shearing blades 9 to open and close, thereby cutting and segmenting the raw materials rotating regularly in the tank 2, breaking the barrier layer formed by the powdered medicine on the surface of the paste medicine.

[0054] The above description is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and inventive concept of the present invention, should be covered within the scope of protection of the present invention.

Claims

1. A clinical pharmaceutical preparation device, comprising a hollow frustum-shaped base (1) and a container (2) with openings at both ends, characterized in that, The tank (2) is vertically fixed to the top of the base (1). The bottom of the tank (2) is rotatably connected to a rotating tube (11) with an outer circle and an inner square through a rotating structure. The top of the rotating tube (11) is fixedly connected to an ear piece (10). The top of the tank (2) is rotatably installed with a circular rotating ring (5). The bottom surface of the rotating ring (5) is fixedly connected to a connecting plate (6). There are multiple shearing and stirring structures that are hinged to each other between the ear piece (10) and the connecting plate (6). The shearing and stirring structure includes two rotating blocks (8). The two rotating blocks (8) are rotatably connected together. Each rotating block (8) has a stirring blade (7) and a shearing cutter (9) fixedly connected to its outer wall. The stirring blade (7) at the top is hinged to the connecting plate (6), and the stirring blade (7) at the bottom is hinged to the ear piece (10).

2. The clinical pharmaceutical preparation equipment according to claim 1, characterized in that, The rotating structure includes an annular piston (12), which is slidably fitted inside the tank (2). A baffle (30) is rotatably installed inside the piston (12), and the rotating tube (11) is rotatably installed in the middle of the baffle (30).

3. The clinical pharmaceutical preparation equipment according to claim 2, characterized in that, The base (1) is provided with a drive structure inside to drive the rotating tube (11) to rotate. The drive structure includes a motor (26) and a square rotating rod (27). The motor (26) is fixed inside the base (1), and the rotating rod (27) is fixed to the output shaft of the motor (26). The rotating rod (27) is slidably fitted inside the rotating tube (11).

4. The clinical pharmaceutical preparation equipment according to claim 3, characterized in that, The base (1) is provided with a limiting structure to restrict the rotation of the baffle (30). The limiting structure includes a slider (25). A sliding hole (28) is vertically opened in the base (1). The slider (25) is slidably fitted in the sliding hole (28). A tension spring (29) is provided at the bottom of the sliding hole (28). The top of the tension spring (29) is fixed to the slider (25). An extension rod (24) is vertically fixed to the top of the slider (25). The bottom surface of the extension rod (24) is fixed to the lower end surface of the baffle (30).

5. The clinical pharmaceutical preparation equipment according to claim 4, characterized in that, The tension spring (29) always applies a downward pulling force to the slider (25).

6. The clinical pharmaceutical preparation equipment according to claim 5, characterized in that, A central gear (15) is fixedly connected to the bottom of the rotating tube (11), a ring gear (13) is fixedly connected to the bottom surface of the piston (12), and a transmission gear (14) is rotatably installed on the bottom surface of the baffle (30). The ring gear (13), the transmission gear (14) and the central gear (15) are matched so that when the central gear (15) rotates, the ring gear (13) is driven to rotate in the opposite direction through the transmission gear (14).

7. The clinical pharmaceutical preparation equipment according to claim 6, characterized in that, The base (1) has a pipe (21) fixed inside, and a wave-shaped guide groove (22) is provided on the inner wall of the pipe (21). An L-shaped guide rod (23) is fixed on the lower end face of the ring gear (13), and the guide rod (23) slides in the guide groove (22).

8. The clinical pharmaceutical preparation equipment according to claim 7, characterized in that, The top of the tank (2) is provided with a threaded part (3), and an end cap (4) is threaded onto the threaded part (3) to seal the top of the tank (2).

9. The clinical pharmaceutical preparation equipment according to claim 8, characterized in that, The outer wall of the end cap (4) is provided with anti-slip texture to increase the coefficient of friction.

10. The clinical pharmaceutical preparation equipment according to claim 9, characterized in that, The piston (12) has a flow channel (16) inside. A circular sealing ring (18) is fixed to the top of the piston (12). Multiple blade-shaped cutting blocks (19) are fixed to the upper surface of the sealing ring (18). Multiple through holes (20) are opened on the sealing ring (18) to accommodate the fluid agent in the tank (2) entering the flow channel (16). Multiple discharge pipes (17) are fixed to the inner ring of the piston (12) at an incline. The discharge pipes (17) are connected to the flow channel (16) to accommodate the discharge of the agent in the flow channel (16).

Images