Vacuum low-temperature evaporation equipment

Abstract

The invention discloses vacuum low-temperature evaporation equipment, and relates to the technical field of low-temperature evaporation. The device comprises a stock solution water tank used for storing and conveying liquid medicine; the raw water valve is used for opening or cutting off a liquid medicine conveying pipeline of the stock solution water tank and is connected with the stock solution water tank through a pipeline; and the filter is used for filtering particle impurities in the liquid medicine and is connected with the raw water valve through a pipeline. The core of the system is energy transfer and recovery of an evaporation internal circulation system, so that generation of secondary steam in internal circulation depends on heating of liquid medicine in the circulation process, energy is released after condensation recovery of the secondary steam, supplementary energy is provided for the circulation process, and an energy closed loop of evaporation-recovery-re-evaporation is formed by the secondary steam and the energy closed loop. Initial energy is provided through primary steam, energy circulation reuse is achieved through secondary steam, energy consumption is greatly reduced, it is guaranteed that feed liquid is evenly heated and continuously evaporated and concentrated, meanwhile, energy recovery reuse of the secondary steam is achieved, and stable operation of equipment is maintained.

Description

Technical Field

[0001] This invention relates to the field of low-temperature evaporation technology, and more specifically to a vacuum low-temperature evaporation device. Background Technology

[0002] In the field of drug research and development and production, purification technology has always been a key factor in determining drug quality and efficacy. Low-temperature evaporators use vacuum decompression technology to make the evaporation temperature significantly lower than the operating temperature of traditional evaporators, thereby effectively protecting the active ingredients of heat-sensitive drugs and avoiding drug degradation and inactivation caused by high temperatures. Low-temperature evaporators have shown unique advantages in the purification process of heat-sensitive drugs such as antibiotics, vitamins, and enzyme preparations.

[0003] Existing vacuum low-temperature evaporation equipment generates a large amount of steam when evaporating and concentrating pharmaceutical solutions. This steam has abundant latent heat, but current vacuum low-temperature evaporation equipment cannot make reasonable use of the latent heat of the steam, resulting in huge energy waste. Therefore, a vacuum low-temperature evaporation equipment is proposed. Summary of the Invention

[0004] The purpose of this invention is to address the problem that current vacuum low-temperature evaporation equipment cannot effectively utilize the latent heat of steam, resulting in huge energy waste. This invention provides a vacuum low-temperature evaporation device.

[0005] To achieve the above objectives, the present invention specifically adopts the following technical solution: A vacuum low-temperature evaporation apparatus, comprising: The concentrate tank is used for storing and transporting the drug solution. Raw water valve, used to open or close the pipeline for transporting medicine liquid in the raw liquid tank, is connected to the raw liquid tank through a pipeline; A filter, used to filter particulate impurities in the medicine solution, is connected to the raw water valve via a pipeline; An evaporation internal circulation system is used to circulate and transport the liquid medicine in a closed loop and evaporate it by heating the liquid medicine, and is connected to the filter through a pipeline; A heat exchange circulation pump is used to provide power for the closed-loop flow of the drug solution in the evaporation internal circulation system, and is connected to the evaporation internal circulation system through a pipeline; A three-way circulation valve is used to switch the flow path of the liquid medicine and is connected to the filter and the heat exchange circulation pump through pipelines. A vacuum generator, by evacuating air, reduces the pressure inside the evaporation internal circulation system to a target negative pressure, and is connected to the evaporation internal circulation system through a pipeline; The concentrate valve is used to control the opening and closing of the concentrated liquid discharge passage, and is connected to the heat exchange circulation pump and the three-way circulation valve through pipelines; The distilled water recycling system is used to recover the distilled water generated by steam heat exchange and condensation and put the distilled water into subsequent cleaning operations. It is connected to the filter and the evaporation internal circulation system through pipelines.

[0006] Furthermore, the evaporation internal circulation system includes: An evaporation chamber is used to inject the liquid medicine to be evaporated and exchange heat with primary steam. The evaporation chamber is connected to the heat exchange circulation pump through a pipeline. A primary steam pipe is installed inside the evaporation chamber and forms a closed loop. It is used to transport primary steam to exchange heat with the liquid medicine inside the evaporation chamber and is connected to an external heat source. A heat exchanger is used to temporarily store the liquid medicine drawn from the original liquid tank and transport it to the evaporation chamber, while exchanging heat between the liquid medicine and secondary steam. It is connected to the evaporation chamber and the three-way circulation valve through pipelines. A secondary steam pipe fitting is installed inside the heat exchanger and forms a closed loop. It is used to transport the secondary steam generated in the evaporation chamber to the heat exchanger and exchange heat with the liquid medicine. It is connected to the evaporation chamber and the distilled water circulation and recovery system through pipelines. A demister is installed above the interior of the evaporation chamber to intercept foam generated when the liquid boils, preventing the foam from carrying active ingredients into the secondary steam pipes.

[0007] Furthermore, the distilled water recycling system includes: A three-way distilled water valve is used to control the discharge and reflux of distilled water and to connect to the secondary steam fittings via a pipeline. A distilled water tank is used to store distilled water generated by secondary steam condensation and is connected to the three-way distilled water valve through a pipeline. A distilled water circulation pump is used to provide power for the discharge and return of distilled water, and is connected to the secondary steam pipe and the distilled water tank through pipelines; A cleaning system is used to perform cleaning operations using distilled water collected inside the distilled water tank, and is connected to the heat exchange circulation pump and the distilled water tank through pipelines.

[0008] Furthermore, the cleaning system includes: The first drain valve is used to control the opening and closing of the sewage discharge pipeline after cleaning, and is connected to the heat exchange circulation pump and the three-way circulation valve through a pipeline; The first cleaning valve is used to control the switch of the distilled water delivery pipeline inside the distilled water tank, and is connected to the filter and the distilled water tank through a pipeline.

[0009] Furthermore, the secondary steam pipe fitting includes a spiral heat exchange steam pipe disposed inside the heat exchanger. The top end of the spiral heat exchange steam pipe is connected to the evaporation chamber via a pipeline, and the bottom end of the spiral heat exchange steam pipe is connected to the three-way distilled water valve, the vacuum generator, and the distilled water circulation pump via a pipeline. A heat-conducting cylindrical frame is disposed inside the three-way distilled water valve. The spiral heat exchange steam pipe is embedded in the inner wall of the heat-conducting cylindrical frame. Multiple evenly distributed liquid flow holes are opened on the side wall of the heat-conducting cylindrical frame. Multiple condensing bridging pipes with both ends connected to the spiral heat exchange steam pipe are fixedly installed on the inner ring of the spiral heat exchange steam pipe.

[0010] Furthermore, the cleaning system also includes: The second cleaning valve is used to control the switch of the external water source input pipeline and is connected to the filter through a pipeline. The second drain valve is used to control the opening and closing of the sewage discharge pipeline generated by the filter cleaning, and is connected to the filter and the first drain valve through a pipeline.

[0011] Furthermore, a flow guide inclined plate is fixedly installed at the bottom end of the heat-conducting cylindrical frame, and the position of the flow guide inclined plate corresponds to that of the condensation bridging pipe.

[0012] Furthermore, a plurality of uniformly distributed capillary condenser tubes are fixedly installed on the outer wall of the condenser bridging tube, and a plurality of protective cylinders are fixedly installed on the outer wall of the heat-conducting cylinder frame. One end of each of the plurality of capillary condenser tubes penetrates the heat-conducting cylinder frame and extends into the interior of the plurality of protective cylinders respectively.

[0013] The beneficial effects of this invention are as follows: 1. The core of this invention is the "energy transfer and recovery" of the evaporation internal circulation system. The generation of secondary steam in the internal circulation depends on the heating of the liquid medicine in the circulation process. The condensation and recovery of secondary steam will release energy and provide supplementary energy for the circulation process. The two form an energy closed loop of "evaporation-recovery-re-evaporation". The primary steam provides the initial energy, and the secondary steam realizes the energy recycling and reuse, which greatly reduces energy consumption, ensures uniform heating of the liquid medicine, and continuous evaporation and concentration. At the same time, the energy of the secondary steam is recovered and reused to maintain the stable operation of the equipment. 2. This invention, by setting up spiral heat exchange steam pipes, can greatly increase the length of the flow path of the liquid medicine in the heat exchanger and secondary steam pipe fittings. Combined with the liquid flow holes on the periphery of the heat-conducting cylinder frame and the staggered condensation bridging pipes in the middle, it greatly increases the heat exchange area between the liquid medicine and the secondary steam, accelerates the phase change of the liquid medicine under heat, thereby improving the efficiency of liquid medicine concentration. At the same time, it accelerates the condensation and liquefaction of the secondary steam, thereby accelerating the return speed of distilled water and completing the rapid replenishment of distilled water in the distilled water tank. 3. By setting capillary condensers, the present invention enables the capillary condensers with capillary structures to have a heat pipe effect, allowing the secondary steam inside the spiral heat exchange steam pipe to be injected into each capillary condenser and rapidly condense and liquefy at the teardrop-shaped outer end of the capillary condenser, greatly improving the heat exchange efficiency of the steam. At the same time, the protective cylinder outside the heat-conducting cylinder frame can protect the capillary condensers, and the guide inclined plate at the bottom of the spiral heat exchange steam pipe can protect the condensation bridging pipe, effectively preventing the circulating liquid from directly impacting the condensation bridging pipe and the capillary condensers. 4. The present invention is equipped with a complete cleaning system. When the equipment completes a batch of concentration tasks or is scheduled for long-term shutdown, the cleaning system can remove residual liquid from the evaporation chamber, heat exchanger, circulation pipeline, and the outer walls of primary steam pipes and secondary steam pipes. This prevents the liquid from crystallizing and corroding equipment parts, ensuring the reliability of the equipment and the purity of the liquid in the next operation. At the same time, the filter is cleaned regularly, which greatly extends the service life of the filter. Attached Figure Description

[0014] Figure 1 This is a schematic diagram of the vacuum low-temperature evaporation equipment of the present invention; Figure 2 This is a first-view three-dimensional structural diagram of the secondary steam pipe fitting of the present invention; Figure 3 This is the present invention. Figure 2 Schematic diagram of the structure at point A in the middle; Figure 4 This is a two-dimensional structural diagram of the secondary steam pipe fitting of the present invention from a second perspective; Figure 5 This is a schematic diagram of the three-dimensional structure of the spiral heat exchange steam pipe of the present invention; Figure 6 This is the present invention. Figure 5 Schematic diagram of the three-dimensional structure at point B; Reference numerals: 00, Raw liquid tank; 01, Raw water valve; 02, Filter; 03, Heat exchange circulation pump; 04, Primary steam fittings; 05, Evaporation chamber; 06, Heat exchanger; 07, Secondary steam fittings; 071, Spiral heat exchange steam pipe; 072, Heat-conducting cylinder frame; 073, Liquid flow orifice; 074, Condensation bridging pipe; 075, Capillary condenser tube; 076, Flow guide inclined plate; 077, Protective cylinder; 08, Three-way circulation valve; 09, Three-way distilled water valve; 10, Vacuum generator; 11, Distilled water circulation pump; 12, First drain valve; 13, Concentrate valve; 14, First cleaning valve; 15, Distilled water tank; 16, Demister; 17, Second drain valve; 18, Second cleaning valve. Detailed Implementation

[0015] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. The components of the embodiments of the present invention described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0016] Therefore, the following detailed description of the embodiments of the invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the invention without inventive effort are within the scope of protection of the invention.

[0017] It should be noted that similar reference numerals and letters in the following figures indicate similar items; therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures. Furthermore, the terms "first," "second," etc., are used only to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0018] In the description of the embodiments of the present invention, it should be noted that the terms "inner", "outer", "upper", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship in which the product of the invention is usually placed when in use. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting the present invention.

[0019] like Figures 1 to 6 As shown, a vacuum low-temperature evaporation device includes: like Figure 1 As shown, the stock solution tank 00 is used for storing and transporting the drug solution; Raw water valve 01 is used to open or close the pipeline for transporting medicine to raw liquid tank 00, and is connected to raw liquid tank 00 through pipeline. Filter 02 is used to filter particulate impurities in the medicine solution and is connected to the raw water valve 01 through a pipeline; The heat exchange circulation pump 03 is used to provide power for the closed-loop flow of the drug solution in the evaporation internal circulation system, and is connected to the evaporation internal circulation system through pipelines. The three-way circulation valve 08 is used to switch the flow path of the medicine solution and is connected to the filter 02 and the heat exchange circulation pump 03 through pipelines. The vacuum generator 10 reduces the pressure in the evaporation internal circulation system to the target negative pressure by evaporating air, and is connected to the evaporation internal circulation system through a pipeline. Concentrate valve 13 is used to control the switch of the concentrated liquid discharge passage, and is connected to heat exchange circulation pump 03 and three-way circulation valve 08 through pipelines; The evaporation internal circulation system is used to circulate and transport the liquid medicine in a closed loop and evaporate it by heating the liquid medicine. It is connected to filter 02 through a pipeline, such as... Figure 1 As shown, specifically, the evaporation internal circulation system includes: Evaporation chamber 05 is used to inject the liquid to be evaporated and exchange heat with primary steam. Evaporation chamber 05 is connected to heat exchange circulation pump 03 through pipeline. The primary steam pipe fitting 04 is located inside the evaporation chamber 05 and forms a closed loop. It is used to transport primary steam to exchange heat with the liquid medicine inside the evaporation chamber 05 and is connected to an external heat source. Heat exchanger 06 is used to temporarily store the liquid medicine drawn from the raw liquid tank 00 and transport it to the evaporation chamber 05, while exchanging heat between the liquid medicine and the secondary steam. It is connected to the evaporation chamber 05 and the three-way circulation valve 08 through pipelines. The secondary steam pipe fitting 07 is installed inside the heat exchanger 06 and forms a closed loop. It is used to transport the secondary steam generated in the evaporation chamber 05 to the heat exchanger 06 and exchange heat with the liquid medicine. It is connected to the evaporation chamber 05 and the distilled water circulation and recovery system through pipelines. Defoamer 16 is located above the interior of evaporation chamber 05 to intercept foam generated when the liquid boils, preventing the foam from carrying the active ingredients into the secondary steam pipe 07 with the secondary steam.

[0020] In this embodiment, the primary steam supplied by the primary steam pipe fitting 04 has two common supply sources: ① waste heat from on-site boiler steam, mainly used in industrial settings to save energy; ② electric heating tubes, mainly used in experimental settings or environments without waste heat, and can adopt heating principles similar to those of electric heaters such as "hot water heaters" on the market.

[0021] More specifically, the liquid circulation process is as follows: ① Initial state: Concentrate valve 13 and first cleaning valve 14 are closed, and the three-way circulation valve 08 is opened in the default state of direct flow. The heat exchange circulation pump 03 draws the initial liquid from the raw liquid tank 00 through the filter 02 and delivers it to the bottom of the evaporation chamber 05 via the three-way circulation valve 08 and heat exchanger 06; ② Start-up stage: The vacuum generator 10 is started, drawing the target negative pressure to lower the boiling point of the liquid to 30-40℃. Simultaneously, an external heat source introduces primary steam into the primary steam pipe 04 to heat the initial liquid inside the evaporation chamber 05; ③ Circulating evaporation stage: The heat exchange circulation pump 03 is started, and the initial liquid is drawn from the raw liquid tank 00 through the filter 02. It is then transported to the bottom of the evaporation chamber 05 through the three-way circulation valve 08 and the heat exchanger 06 until the dynamic liquid level inside the heat exchanger 06 and the evaporation chamber 05 reaches the threshold. The raw water valve 01 is then closed. The liquid at the bottom of the evaporation chamber 05 exchanges heat with the primary steam inside the primary steam pipe 04 and boils under negative pressure to generate secondary steam. The concentration of the liquid itself increases due to water evaporation. ④ Recovery circulation: The secondary steam passes through the demister 16 and enters the secondary steam pipe 07. The concentrated liquid is then transported back to the heat exchanger 06 through the heat exchange circulation pump 03, where it is reheated by the secondary steam in the secondary steam pipe 07 and enters the evaporation chamber 05 to form a closed loop. ⑤ Distillation return water: During the circulation process, the condensate generated after the secondary steam heat exchange continuously flows back to the distillation water tank 15 for temporary storage through the three-way distillation water valve 09 in the angle state; ⑥ Concentration water replenishment: If the concentration of the medicine in the evaporation chamber 05 and heat exchanger 06 is not up to the qualified standard during equipment operation, but the liquid level has dropped to a low level and cannot meet the normal circulation requirements, the raw water valve 01 is opened, and the heat exchange circulation pump 03 draws the medicine in the raw liquid tank 00 through the filter 02 and mixes it with the concentrated medicine in the heat exchanger 06 and evaporation chamber 05 to participate in the circulation evaporation. When the liquid level returns to the normal range, the raw water valve 01 is closed, the normal circulation state is restored, and the concentration continues.

[0022] Discharge process: ① Concentration detection: As the internal circulation proceeds, the concentration of the liquid in the heat exchanger 06 and evaporation chamber 05 continues to increase. When the concentration reaches the qualified range, the three-way circulation valve 08 switches to the angle valve, disconnecting the internal circulation path, and the concentrate valve 13 opens; ② Concentrate discharge: The heat exchange circulation pump 03 runs continuously, drawing the concentrated liquid from the bottom of the heat exchanger 06 and evaporation chamber 05 respectively, and merging them to be transported to the downstream production equipment through the concentrate valve 13 to complete one concentration.

[0023] The core of this vacuum low-temperature evaporation equipment is the "energy transfer and recovery" of the evaporation internal circulation system. The generation of secondary steam in the internal circulation depends on the heating of the liquid in the circulation process. The condensation and recovery of the secondary steam releases energy, providing supplementary energy for the circulation process. The two form an energy closed loop of "evaporation-recovery-re-evaporation". The primary steam provides the initial energy, and the secondary steam realizes the energy recycling and reuse, which greatly reduces energy consumption, ensures uniform heating of the liquid, and continuous evaporation and concentration. At the same time, the energy of the secondary steam is recovered and reused to maintain the stable operation of the equipment.

[0024] like Figure 2 , Figure 5 As shown, specifically, the secondary steam pipe fitting 07 includes a spiral heat exchange steam pipe 071 disposed inside the heat exchanger 06. The top end of the spiral heat exchange steam pipe 071 is connected to the evaporation chamber 05 through a pipeline, and the bottom end of the spiral heat exchange steam pipe 071 is connected to the three-way distilled water valve 09, the vacuum generator 10, and the distilled water circulation pump 11 through a pipeline. The three-way distilled water valve 09 is provided with a heat-conducting cylindrical frame 072 inside. The spiral heat exchange steam pipe 071 is embedded in the inner wall of the heat-conducting cylindrical frame 072. Multiple evenly distributed liquid flow holes 073 are opened on the side wall of the heat-conducting cylindrical frame 072. Multiple condensing bridging pipes 074 with both ends connected to the spiral heat exchange steam pipe 071 are fixedly installed on the inner ring of the spiral heat exchange steam pipe 071.

[0025] More specifically, by setting up spiral heat exchange steam pipes 071, the spirally distributed spiral heat exchange steam pipes 071 can greatly increase the length of the flow path of the liquid medicine in the heat exchanger 06 and the secondary steam pipe fittings 07. Combined with the liquid flow holes 073 on the periphery of the heat-conducting cylindrical frame 072 and the staggered condensation bridging pipes 074 in the middle, the heat exchange area between the liquid medicine and the secondary steam is greatly increased, accelerating the phase change of the liquid medicine and thus improving the efficiency of liquid medicine concentration. At the same time, it accelerates the condensation and liquefaction of the secondary steam, thereby accelerating the return speed of distilled water and completing the rapid replenishment of distilled water in the distilled water tank 15.

[0026] like Figure 3 , Figure 4 , Figure 6 As shown, specifically, multiple uniformly distributed capillary condenser tubes 075 are fixedly installed on the outer wall of the condenser bridging tube 074, and multiple protective cylinders 077 are fixedly installed on the outer wall of the heat-conducting cylinder frame 072. One end of each of the multiple capillary condenser tubes 075 passes through the heat-conducting cylinder frame 072 and extends into the interior of the multiple protective cylinders 077 respectively. A flow-guiding inclined plate 076 is fixedly installed at the bottom end of the heat-conducting cylinder frame 072, and the flow-guiding inclined plate 076 corresponds to the position of the condenser bridging tube 074.

[0027] More specifically, by setting up capillary condensers 075, the capillary condensers 075 with capillary structures have a heat pipe effect, allowing the secondary steam inside the spiral heat exchange steam pipe 071 to be injected into each capillary condenser 075 and rapidly condense and liquefy at the teardrop-shaped outer end of the capillary condenser 075, greatly improving the heat exchange efficiency of the steam. At the same time, the protective cylinder 077 outside the heat-conducting cylinder frame 072 can protect the capillary condensers 075, and the guide inclined plate 076 at the bottom of the spiral heat exchange steam pipe 071 can protect the condensing bridging pipe 074, effectively preventing the circulating liquid from directly impacting the condensing bridging pipe 074 and the capillary condensers 075.

[0028] The distilled water recycling system is used to recover the distilled water generated by steam heat exchange and condensation, and then reuse the distilled water in subsequent cleaning operations. It is connected to filter 02 and the evaporator internal circulation system via pipelines. Figure 1 As shown, specifically, the distilled water recycling system includes: The three-way distilled water valve 09 is used to control the discharge and reflux of distilled water and is connected to the secondary steam fitting 07 via a pipeline. Distilled water tank 15 is used to store distilled water generated by secondary steam condensation and is connected to three-way distilled water valve 09 through a pipeline; The distilled water circulation pump 11 is used to provide power for the discharge and return of distilled water, and is connected to the secondary steam pipe fitting 07 and the distilled water tank 15 through pipelines.

[0029] In this embodiment, it is not necessary to start the vacuum generator 10 and the distilled water circulation pump 11 during the cleaning process. If the residual liquid is highly corrosive, a cleaning solution compatible with the equipment material can be used. After cleaning, rinse again with clean water.

[0030] More specifically, the distillation recovery process is as follows: ① Distillation recovery: During heat exchange, the secondary steam in the secondary steam pipe fitting 07 releases a large amount of latent heat, which condenses to generate distilled water. The distilled water is then transported to the distilled water tank 15 for temporary storage via the three-way distilled water valve 09 in the angled state; ② Safety overflow: When the liquid level is too high, the three-way distilled water valve 09 switches to straight-through to discharge excess product water to the external pipeline, maintaining a stable liquid level.

[0031] The cleaning system, which uses distilled water collected inside the distilled water tank 15 for cleaning operations, is connected to the heat exchange circulation pump 03 and the distilled water tank 15 via pipelines, such as... Figure 1 As shown, specifically, the cleaning system includes: The first drain valve 12 is used to control the opening and closing of the sewage discharge pipeline after cleaning, and is connected to the heat exchange circulation pump 03 and the three-way circulation valve 08 through the pipeline. The first cleaning valve 14 is used to control the switch of the distilled water delivery pipeline inside the distilled water tank 15, and is connected to the filter 02 and the distilled water tank 15 through the pipeline. The second cleaning valve 18 is used to control the switch of the external water source input pipeline and is connected to the filter 02 through a pipeline; The second drain valve 17 is used to control the opening and closing of the sewage discharge pipeline generated during the cleaning of filter 02, and is connected to filter 02 and the first drain valve 12 through a pipeline.

[0032] More specifically, the cleaning process is as follows: ① Pretreatment: Close the raw water valve 01 and the concentrated water valve 13 to disconnect the water replenishment and concentrated liquid discharge pathways; ② Inject clean water: Open the first cleaning valve 14 to draw in distilled water through the heat exchange circulation pump 03, and the distilled water is filtered through the filter 02 to remove impurities; ③ Cleaning circulation: The distilled water flows along the path of the liquid circulation, passing through key components such as the primary steam pipe 04, evaporation chamber 05, heat exchanger 06, and three-way circulation valve 08, to flush away residual liquid; ④ Sewage discharge stage: Open the first drain valve 12, and the heat exchange circulation pump 03 will... Sewage is discharged until the drainage is clear and transparent with no obvious impurities; ⑤ Finishing: Close the first cleaning valve 14 and the first drain valve 12 to drain the remaining water; ⑥ Filtration maintenance: Close all other valves, open the second cleaning valve 18, the second drain valve 17, and the first drain valve 12, and inject clean water from the external water source into the output end of the filter 02 through the second cleaning valve 18, so that the clean water backwashes the filter 02, flushing down the dirt intercepted upstream of the filter 02, and discharging it along with the sewage through the second drain valve 17 and the first drain valve 12, completing the cleaning.

[0033] The vacuum low-temperature evaporation equipment is equipped with a complete cleaning system. When the equipment completes a batch of concentration tasks or is scheduled for long-term shutdown, the cleaning system can remove residual chemical solution from the evaporation chamber 05, heat exchanger 06, circulation pipeline, and the outer walls of primary steam pipe fittings 04 and secondary steam pipe fittings 07. This prevents chemical solution crystallization and corrosion of equipment components, ensuring the reliability of the equipment and the purity of the chemical solution in the next operation. At the same time, the filter 02 is cleaned regularly, which greatly extends the service life of the filter 02.

[0034] In summary: the operating procedure of this vacuum low-temperature evaporation equipment is as follows: I. Liquid Circulation Process: ① Initial State: Concentrate valve 13 and first cleaning valve 14 are closed. The three-way circulation valve 08 is opened in the default state of direct flow. The heat exchange circulation pump 03 draws the initial liquid from the raw liquid tank 00 through the filter 02 and delivers it to the bottom of the evaporation chamber 05 through the three-way circulation valve 08 and heat exchanger 06; ② Start-up Stage: The vacuum generator 10 is started, drawing the target negative pressure to lower the boiling point of the liquid to 30-40℃. At the same time, an external heat source introduces primary steam into the primary steam pipe 04 to heat the initial liquid inside the evaporation chamber 05; ③ Circulating evaporation stage: The heat exchange circulation pump 03 is started, and the initial liquid is drawn from the raw liquid tank 00 through the filter 02. It is then transported to the bottom of the evaporation chamber 05 through the three-way circulation valve 08 and the heat exchanger 06 until the dynamic liquid level inside the heat exchanger 06 and the evaporation chamber 05 reaches the threshold. The raw water valve 01 is then closed. The liquid at the bottom of the evaporation chamber 05 exchanges heat with the primary steam inside the primary steam pipe 04 and boils under negative pressure to generate secondary steam. The concentration of the liquid itself increases due to water evaporation. ④ Recovery circulation: The secondary steam passes through the demister 16 and enters the secondary steam pipe 07. The concentrated liquid is then transported back to the heat exchanger 06 through the heat exchange circulation pump 03, where it is reheated by the secondary steam in the secondary steam pipe 07 and enters the evaporation chamber 05 to form a closed loop. ⑤ Distillation return water: During the circulation process, the condensate generated after the secondary steam heat exchange continuously flows back to the distillation water tank 15 for temporary storage through the three-way distillation water valve 09 in the angle state; ⑥ Concentration water replenishment: If the concentration of the medicine in the evaporation chamber 05 and heat exchanger 06 is not up to the qualified standard during equipment operation, but the liquid level has dropped to a low level and cannot meet the normal circulation requirements, the raw water valve 01 is opened, and the heat exchange circulation pump 03 draws the medicine in the raw liquid tank 00 through the filter 02 and mixes it with the concentrated medicine in the heat exchanger 06 and evaporation chamber 05 to participate in the circulation evaporation. When the liquid level returns to the normal range, the raw water valve 01 is closed, the normal circulation state is restored, and the concentration continues.

[0035] II. Discharge Process: ① Concentration Detection: As the internal circulation proceeds, the concentration of the liquid in the heat exchanger 06 and evaporation chamber 05 continues to increase. When the concentration reaches the qualified range, the three-way circulation valve 08 switches to the angle valve, disconnecting the internal circulation path, and the concentrate valve 13 opens; ② Concentrate Discharge: The heat exchange circulation pump 03 runs continuously, drawing the concentrated liquid from the bottom of the heat exchanger 06 and evaporation chamber 05 respectively, and converging to transport it to the downstream production equipment through the concentrate valve 13, completing one concentration.

[0036] III. Distillation Recovery Process: ① Distillation Recovery: During heat exchange, the secondary steam in the secondary steam pipe fitting 07 releases a large amount of latent heat, which condenses to generate distilled water. The distilled water is then transported to the distilled water tank 15 for temporary storage via the three-way distilled water valve 09 in the angled state; ② Safety Overflow: When the liquid level is too high, the three-way distilled water valve 09 switches to straight-through to discharge excess product water to the external pipeline, maintaining a stable liquid level.

[0037] IV. Cleaning Process: ① Pretreatment: Close the raw water valve 01 and concentrated water valve 13 to disconnect the water replenishment and concentrated liquid discharge pathways; ② Injection of clean water: Open the first cleaning valve 14 to draw in distilled water through the heat exchange circulation pump 03, and the distilled water is filtered through the filter 02 to remove impurities; ③ Cleaning circulation: The distilled water flows along the path of the liquid circulation, passing through key components such as the primary steam pipe fitting 04, evaporation chamber 05, heat exchanger 06, and three-way circulation valve 08, to flush away residual liquid; ④ Sewage discharge stage: Open the first sewage discharge valve 12, and the heat exchange circulation pump 03 discharges the sewage. Discharge until the drain is clear and free of obvious impurities; ⑤ Finishing: Close the first cleaning valve 14 and the first drain valve 12 to drain the remaining water; ⑥ Filter maintenance: Close all other valves, open the second cleaning valve 18, the second drain valve 17, and the first drain valve 12, and inject clean water from the external water source into the output end of the filter 02 through the second cleaning valve 18, so that the clean water backwashes the filter 02, flushing down the dirt intercepted upstream of the filter 02, and discharging it along with the sewage through the second drain valve 17 and the first drain valve 12, thus completing the cleaning.

[0038] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely principles of the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed invention. The scope of protection claimed by the appended claims and their equivalents is defined.

Claims

1. A vacuum low-temperature evaporation device, characterized in that, include: The stock solution tank (00) is used for storing and transporting the drug solution; Raw water valve (01) is used to open or close the pipeline for transporting medicine in the raw liquid tank (00), and is connected to the raw liquid tank (00) through a pipeline; The filter (02) is used to filter particulate impurities in the medicine solution and is connected to the raw water valve (01) through a pipeline; An evaporation internal circulation system is used to circulate and transport the liquid medicine in a closed loop and evaporate it by heating the liquid medicine, and is connected to the filter (02) through a pipeline; A heat exchange circulation pump (03) is used to provide power for the closed-loop flow of the drug solution in the evaporation internal circulation system and is connected to the evaporation internal circulation system through a pipeline; The three-way circulation valve (08) is used to switch the flow path of the liquid medicine and is connected to the filter (02) and the heat exchange circulation pump (03) through pipelines; The vacuum generator (10) reduces the pressure in the evaporation internal circulation system to the target negative pressure by evaporating air, and is connected to the evaporation internal circulation system through a pipeline; The concentrate valve (13) is used to control the switch of the concentrated liquid discharge passage and is connected to the heat exchange circulation pump (03) and the three-way circulation valve (08) through pipelines; The distilled water recycling system is used to recycle the distilled water generated by steam heat exchange and condensation and put the distilled water into subsequent cleaning operations. It is connected to the filter (02) and the evaporation internal circulation system through pipelines.

2. The vacuum low-temperature evaporation equipment according to claim 1, characterized in that, The evaporation internal circulation system includes: Evaporation chamber (05) is used to inject the liquid medicine to be evaporated and exchange heat with primary steam. The evaporation chamber (05) is connected to the heat exchange circulation pump (03) through a pipeline. A primary steam pipe fitting (04) is installed inside the evaporation chamber (05) and forms a closed loop. It is used to transport primary steam to exchange heat with the liquid medicine inside the evaporation chamber (05) and is connected to an external heat source. The heat exchanger (06) is used to temporarily store the medicine liquid drawn from the original liquid tank (00) and transport it to the evaporation chamber (05), while exchanging heat between the medicine liquid and the secondary steam. It is connected to the evaporation chamber (05) and the three-way circulation valve (08) through pipelines. The secondary steam pipe fitting (07) is installed inside the heat exchanger (06) and forms a closed loop. It is used to transport the secondary steam generated in the evaporation chamber (05) to the heat exchanger (06) and exchange heat with the liquid medicine. It is connected to the evaporation chamber (05) and the distilled water circulation and recovery system through pipelines. The demister (16) is located above the interior of the evaporation chamber (05) to intercept the foam generated when the liquid boils, and to prevent the foam from carrying the active ingredients into the secondary steam pipe (07) with the secondary steam.

3. The vacuum low-temperature evaporation equipment according to claim 2, characterized in that, The distilled water recycling system includes: The three-way distilled water valve (09) is used to control the discharge and reflux of distilled water and is connected to the secondary steam fitting (07) through a pipeline. A distilled water tank (15) is used to store distilled water generated by secondary steam condensation and is connected to the three-way distilled water valve (09) through a pipeline; A distilled water circulation pump (11) is used to provide power for the discharge and return of distilled water, and is connected to the secondary steam pipe fitting (07) and the distilled water tank (15) through pipelines; The cleaning system is used to perform cleaning operations using distilled water collected inside the distilled water tank (15), and is connected to the heat exchange circulation pump (03) and the distilled water tank (15) through pipelines.

4. The vacuum low-temperature evaporation equipment according to claim 3, characterized in that, The cleaning system includes: The first drain valve (12) is used to control the opening and closing of the sewage discharge pipeline after cleaning, and is connected to the heat exchange circulation pump (03) and the three-way circulation valve (08) through a pipeline; The first cleaning valve (14) is used to control the switch of the distilled water delivery pipeline inside the distilled water tank (15), and is connected to the filter (02) and the distilled water tank (15) through pipeline.

5. The vacuum low-temperature evaporation equipment according to claim 3, characterized in that, The secondary steam pipe fitting (07) includes a spiral heat exchange steam pipe (071) disposed inside the heat exchanger (06). The top end of the spiral heat exchange steam pipe (071) is connected to the evaporation chamber (05) through a pipe. The bottom end of the spiral heat exchange steam pipe (071) is connected to the three-way distilled water valve (09), the vacuum generator (10), and the distilled water circulation pump (11) through a pipe. The three-way distilled water valve (09) is provided with a heat-conducting cylindrical frame (072) inside. The spiral heat exchange steam pipe (071) is embedded in the inner wall of the heat-conducting cylindrical frame (072). The side wall of the heat-conducting cylindrical frame (072) is provided with a plurality of evenly distributed liquid flow holes (073). The inner ring of the spiral heat exchange steam pipe (071) is fixedly installed with a plurality of condensing bridging pipes (074) whose two ends are connected to the spiral heat exchange steam pipe (071).

6. The vacuum low-temperature evaporation equipment according to claim 4, characterized in that, The cleaning system also includes: The second cleaning valve (18) is used to control the switch of the external water source input pipeline and is connected to the filter (02) through a pipeline; The second drain valve (17) is used to control the opening and closing of the sewage discharge pipeline generated by the cleaning of the filter (02), and is connected to the filter (02) and the first drain valve (12) through a pipeline.

7. The vacuum low-temperature evaporation equipment according to claim 5, characterized in that, The bottom end of the heat-conducting cylinder frame (072) is fixedly installed with a flow-guiding inclined plate (076), and the flow-guiding inclined plate (076) corresponds to the position of the condensation bridging pipe (074).

8. The vacuum low-temperature evaporation equipment according to claim 5, characterized in that, The outer wall of the condenser bridging tube (074) is fixedly installed with a plurality of uniformly distributed capillary condenser tubes (075), and the outer wall of the heat-conducting cylinder frame (072) is fixedly installed with a plurality of protective cylinders (077). One end of each of the plurality of capillary condenser tubes (075) passes through the heat-conducting cylinder frame (072) and extends into the interior of the plurality of protective cylinders (077).

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