Pharmaceutical experiment dissolver

Abstract

The utility model relates to the technical field of pharmaceutical experiment tools, in particular to a pharmaceutical experiment dissolver which comprises a device base, a fixed circular truncated cone is fixedly connected to the middle of the top end of the device base, a dissolving bottle is inserted into the fixed circular truncated cone in a sliding mode, and a drainage tube is inserted into the top end of the dissolving bottle in a communicated mode. A stirring device is arranged at the bottom end of the device base; a connecting rod is fixedly connected to the position, located in the stirring device, of the output end of the motor, the outer surface of the connecting rod is fixedly sleeved with a first bevel gear, the upper side and the lower side of the surface of the first bevel gear are engaged with a second bevel gear and a third bevel gear correspondingly, and a rotating rod is fixedly inserted into the middle of the second bevel gear. Through cooperative use of the motor, the first bevel gear, the second bevel gear, the third bevel gear, the connecting column, the rotating rod, the stirring rod and the circular groove, the purpose of more uniform dissolution of liquid medicine can be achieved, and contact between medicine and a solvent is promoted.

Description

Technical Field

[0001] The utility model relates to the technical field of pharmaceutical experimental tools, in particular to a pharmaceutical experimental dissolver. Background Art

[0002] Pharmaceutical experimental dissolver is a common device used to evaluate the dissolution characteristics of drugs and drug preparations under physiological simulation conditions. In the process of drug development and manufacturing, the solubility of drugs is an important consideration, which can affect the dissolution rate, bioavailability and oral properties of drugs. Therefore, the use of pharmaceutical experimental dissolver can be used to test the solubility of drugs and obtain some important data on drug solubility.

[0003] When using existing pharmaceutical dissolvers, some reagents are difficult to fully dissolve, requiring workers to shake for a long time, which greatly increases the worker's workload. At the same time, the internal liquid is prone to overflow during stirring, which creates risks and is also prone to pollution, making it inconvenient to use.

[0004] Therefore, we proposed a pharmaceutical experimental dissolver to solve the above problems. Utility Model Content

[0005] The purpose of the utility model is to provide a pharmaceutical experimental dissolver to solve the problems mentioned in the above background technology that pharmaceutical dissolution requires workers to spend a lot of time stirring, which is inconvenient to use, and the liquid is prone to splashing during stirring, causing risks and pollution.

[0006] To achieve the above purpose, the utility model provides the following technical solution: a pharmaceutical experiment dissolver, comprising:

[0007] The device base is provided with a control switch on one side of the device base, the top of the device base is fixedly connected with a support frame, and one side of the support frame is connected with a card block in a snap-fitting manner, a fixed round table is fixedly connected to the middle of the top of the device base, a dissolving bottle is slidably inserted inside the fixed round table, a drainage tube is connected and inserted at the top of the dissolving bottle, a stirring device is provided at the bottom end of the device base, and a feeding mechanism is provided above the support frame;

[0008] The stirring device includes a square box, and the stirring device is fixed under the device base. A motor is installed on one side of the stirring device. The output end of the motor is located inside the stirring device and is fixedly connected to a connecting rod. A first bevel gear is fixedly sleeved on the outer surface of the connecting rod. The second bevel gear and the third bevel gear are respectively meshed on the upper and lower sides of the surface of the first bevel gear. A rotating rod is fixedly inserted in the middle of the second bevel gear, and a connecting column is fixedly inserted inside the third bevel gear.

[0009] Preferably, the support frame is configured to be in an inverted "U" shape, a circular groove is provided inside the top end of the support frame, and the middle of the circular groove is rotatably connected to the top end of the dissolving bottle.

[0010] Preferably, a rotating rod is rotatably inserted inside the connecting column, the top end of the connecting column passes through the device base and is fixedly connected to the dissolution bottle, and the rotating rod passes through the device base and extends to the outer surface of the dissolution bottle and is fixedly connected to a stirring rod.

[0011] Preferably, the feeding mechanism includes a limiting column fixed on both sides of the top of the support frame, the internal connection of the drainage tube is connected with a funnel-shaped tube, both sides of the outer surface of the funnel-shaped tube are fixedly connected with bumps, and the inner wall of the funnel-shaped tube is fixedly connected with a filter.

[0012] Preferably, a groove is provided at the top of the limiting column, and the groove is matched with the protrusion, and the two are slidably inserted and connected.

[0013] Compared with the prior art, the beneficial effects of the utility model are: the utility model;

[0014] Through the coordinated use of the motor, the first bevel gear, the second bevel gear, the third bevel gear, the connecting column, the rotating rod, the stirring rod and the circular groove, the purpose of making the drug solution dissolve more evenly can be achieved, the contact between the drug and the solvent can be promoted, and drugs with different solubilities can be fully dissolved, avoiding the situation of local accumulation or precipitation of drugs, thereby helping to speed up the release and absorption process of the drugs, while reducing the time required for the dissolution of the drugs, reducing unnecessary time waste of staff, and improving work efficiency.

[0015] Through the coordinated use of drainage tubes, limit columns, funnel-shaped tubes, bumps and filters, the purpose of preventing liquid from flowing out during dissolution can be achieved, reducing the waste of liquid medicine and laboratory pollution, reducing the chance of splashing onto the bodies of staff, improving the safety of the experiment, and improving the stability of the stirring effect, thereby improving the efficiency of drug dissolution, reducing sample loss and waste, and allowing the drug to exert its original effect and maintain its original dosage. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0017] Figure 1 It is a schematic diagram of a three-dimensional front view of the structure of the utility model;

[0018] Figure 2 It is a schematic diagram of a three-dimensional front view section of the structure of the utility model;

[0019] Figure 3 It is a three-dimensional front view cross-sectional schematic diagram of a square box of the utility model;

[0020] Figure 4 It is a three-dimensional front exploded schematic diagram of a local structure of the utility model;

[0021] Figure 5 It is a three-dimensional front exploded schematic diagram of a local structure of the utility model.

[0022] In the figure: 1. device base; 2. control switch; 3. fixed round table; 4. motor; 5. support frame; 6. dissolving bottle; 7. block; 8. stirring device; 81. square box; 82. connecting rod; 83. first bevel gear; 84. second bevel gear; 85. third bevel gear; 86. connecting column; 87. rotating rod; 88. stirring rod; 9. drainage tube; 10. limiting column; 11. funnel-shaped tube; 12. circular groove; 13. protrusion; 14. filter. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0024] See also Figure 1-5 , an embodiment provided by the utility model: a pharmaceutical experiment dissolver, comprising:

[0025] The device base 1 has a control switch 2 disposed on one side of the device base 1, a support frame 5 is fixedly connected to the top of the device base 1, and a clamping block 7 is connected to one side of the support frame 5, a fixed truncated table 3 is fixedly connected to the middle of the top of the device base 1, a dissolving bottle 6 is slidably inserted inside the fixed truncated table 3, a drainage tube 9 is connected and inserted at the top of the dissolving bottle 6, a stirring device 8 is disposed at the bottom of the device base 1, and a feeding mechanism is disposed above the support frame 5;

[0026] The stirring device 8 includes a square box 81, which is fixed under the device base 1. A motor 4 is installed on one side of the stirring device 8. The output end of the motor 4 is located inside the stirring device 8 and is fixedly connected to a connecting rod 82. A first bevel gear 83 is fixedly sleeved on the outer surface of the connecting rod 82. The upper and lower sides of the surface of the first bevel gear 83 are respectively meshed with a second bevel gear 84 and a third bevel gear 85. A rotating rod 87 is fixedly inserted in the middle of the second bevel gear 84, and a connecting column 86 is fixedly inserted inside the third bevel gear 85.

[0027] Furthermore, according to the attached Figure 1 , attached Figure 2 and attached Figure 4 As shown, the support frame 5 is configured to be in an inverted "U" shape, a circular groove 12 is provided inside the top of the support frame 5, and the middle of the circular groove 12 is rotatably connected to the top of the dissolving bottle 6, which improves the stability during stirring and promotes the full dissolution of the drug.

[0028] Furthermore, according to the attached Figure 2 and attached Figure 3 As shown, a rotating rod 87 is inserted into the interior of the connecting column 86 for rotation. The top of the connecting column 86 passes through the device base 1 and is fixedly connected to the dissolving bottle 6. The rotating rod 87 passes through the device base 1 and extends to the outer surface of the dissolving bottle 6, and a stirring rod 88 is fixedly connected around it. This fully dissolves the medicine in the container, speeds up the dissolution of the medicine, saves the required time, and greatly improves the work efficiency.

[0029] Furthermore, according to the attached Figure 1 , attached Figure 4 and attached Figure 5 As shown, the feeding mechanism includes a limit column 10, which is fixed on both sides of the top of the support frame 5. A funnel-shaped tube 11 is inserted into the interior of the drainage tube 9. Bumps 13 are fixedly connected to both sides of the outer surface of the funnel-shaped tube 11. A filter screen 14 is fixedly connected to the inner wall of the funnel-shaped tube 11 to prevent liquid from splashing during stirring, protect the safety of the staff, and reduce the occurrence of liquid medicine contamination.

[0030] Furthermore, according to the attached Figure 5 As shown, a groove is provided at the top of the limiting column 10, and the groove is matched with the protrusion 13, and the two are slidably connected and can be replaced to prevent internal blockage during long-term use and improve the flexibility of use.

[0031] Working principle: put the whole device in a suitable position, provide power source for the whole device through an external power supply, the staff starts working by pressing the control switch 2, puts the dissolving bottle 6 on the top of the fixed truncated table 3, so that the top of the dissolving bottle 6 is located in the circular groove 12, and then engages the block 7 with the support frame 5;

[0032] Then, the drainage tube 9 and the funnel-shaped tube 11 are integrally inserted into the top of the dissolving bottle 6, so that the protrusions 13 on both sides of the funnel-shaped tube 11 are located in the grooves of the limiting column 10 and are engaged, and then different liquid medicines are poured into the funnel-shaped tube 11, and the impurities and floating foam in the liquid medicines are filtered by the filter screen 14, and the liquid medicines flow along the funnel-shaped tube 11 through the drainage tube 9 to the inside of the dissolving bottle 6;

[0033] During the preparation work, after pressing the control switch 2, the motor 4 starts working, and the output end of the motor 4 drives the connecting rod 82 to rotate. The rotation of the connecting rod 82 drives the first bevel gear 83 inside the square box 81 to rotate synchronously, and the rotation of the first bevel gear 83 makes the second bevel gear 84 and the third bevel gear 85 meshing on both sides of the surface rotate synchronously, and the rotation of the third bevel gear 85 drives the top of the dissolving bottle 6 to rotate in the circular groove 12, and at the same time, the bottom end of the dissolving bottle 6 rotates on the top of the fixed truncated table 3. At this time, the second bevel gear 84 drives the rotating rod 87 to rotate synchronously, and the rotating rod 87 rotates inside the connecting column 86. The rotating rod 87 drives multiple groups of stirring rods 88 to fully stir the liquid inside the dissolving bottle 6. After stirring, remove the block 7 and then take out the dissolving bottle 6.

[0034] The above is the entire working principle of the utility model.

[0035] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

Claims

1. A pharmaceutical experiment dissolver, characterized in that: include: A device base (1), a control switch (2) is provided on one side of the device base (1), a support frame (5) is fixedly connected to the top of the device base (1), and a clamping block (7) is snap-connected to one side of the support frame (5), a fixed truncated table (3) is fixedly connected to the middle of the top of the device base (1), a dissolving bottle (6) is slidably inserted inside the fixed truncated table (3), a drainage tube (9) is connected and inserted at the top of the dissolving bottle (6), a stirring device (8) is provided at the bottom end of the device base (1), and a feeding mechanism is provided above the support frame (5); The stirring device (8) comprises a square box (81). The stirring device (8) is fixed under the device base (1). A motor (4) is installed on one side of the stirring device (8). The output end of the motor (4) is located inside the stirring device (8) and is fixedly connected to a connecting rod (82). A first bevel gear (83) is fixedly sleeved on the outer surface of the connecting rod (82). A second bevel gear (84) and a third bevel gear (85) are respectively meshed on the upper and lower sides of the surface of the first bevel gear (83). A rotating rod (87) is fixedly inserted in the middle of the second bevel gear (84). A connecting column (86) is fixedly inserted inside the third bevel gear (85).

2. A pharmaceutical experiment dissolver according to claim 1, characterized in that: The support frame (5) is arranged in an inverted "U" shape, a circular groove (12) is provided inside the top end of the support frame (5), and the middle of the circular groove (12) is rotatably connected to the top end of the dissolving bottle (6).

3. A pharmaceutical experiment dissolver according to claim 1, characterized in that: A rotating rod (87) is rotatably inserted inside the connecting column (86); the top end of the connecting column (86) passes through the device base (1) and is fixedly connected to the dissolving bottle (6); the rotating rod (87) passes through the device base (1) and extends to the outer surface of the dissolving bottle (6), where a stirring rod (88) is fixedly connected around it.

4. A pharmaceutical experiment dissolver according to claim 1, characterized in that: The feeding mechanism comprises a limiting column (10), wherein the limiting column (10) is fixed on both sides of the top end of the support frame (5), the interior of the drainage tube (9) is connected and a funnel-shaped tube (11) is inserted therein, protrusions (13) are fixedly connected to both sides of the outer surface of the funnel-shaped tube (11), and a filter screen (14) is fixedly connected to the inner wall of the funnel-shaped tube (11).

5. A pharmaceutical experimental dissolver according to claim 4, characterized in that: The top end of the limiting column (10) is provided with a groove, and the groove is matched with the protrusion (13), and the two are slidably inserted and connected.

Images