Cell screening device for stem cells
By introducing a disinfection box and a motor-driven transmission system into the stem cell cell screening device, the problem of difficulty in disinfection after separation is solved, rapid disinfection of test tubes and efficient separation of cells are achieved, and operation safety is improved.
Patent Information
- Application Number
- CN202420693235.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-03
- Publication Date
- 2024-12-20
- Estimated Expiration
- 2034-04-03
AI Technical Summary
The existing stem cell cell screening devices are inconvenient for disinfection after separation, and manual operation leads to the diagnosis of cell loss and poor safety protection.
A cell screening device including a disinfection box, a separation box, a storage box and a motor box is designed to quickly disinfect the test tubes through ultraviolet lights, and a motor drives the transmission rod and turntable to rotate to achieve cell separation.
The rapid disinfection of test tubes and efficient separation of cells are achieved, reducing the loss of diagnostic cells and improving operational safety.
Smart Images

Figure CN222205193U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of cell screening, in particular to a cell screening device for stem cells. Background Art
[0002] By observing the cell preparation of various tissues of the human body, we can know whether the human body has lesions. The cell preparation process is as follows: first, the sample is collected, and then the sample is centrifuged for a specific time and number of times using a centrifuge, and the supernatant containing mucus, red blood cell fragments and other necrotic cell components is discarded, and then the cell adhesion packaging fluid is added, and finally a thin layer of cell smear with a single layer of cell distribution is made, and then artificial staining is performed. However, it is generally necessary to manually centrifuge the cells and discard the supernatant containing mucus, red blood cell fragments and other necrotic cell components. These preliminary treatments are often performed manually, and human error can easily cause the loss of diagnostic cells. In addition, the operator directly contacts the specimen, and the safety protection is poor;
[0003] After searching, the applicant found that a Chinese patent disclosed "a cell screening device for stem cells", and its publication (announcement) number is "CN106289908A". This patent mainly sets the sample turntable on the periphery of the centrifugal turntable, the cantilever moves horizontally, the sampling mechanism absorbs the sample in the sample bottle, and then moves horizontally above the centrifugal turntable to drop the sample into the centrifugal chamber to complete a sample transfer operation. However, it is inconvenient to disinfect after separation. Therefore, we propose a cell screening device for stem cells. Utility Model Content
[0004] The utility model aims to provide a cell screening device for stem cells.
[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a cell screening device for stem cells, comprising a cell screening body, wherein the cell screening body comprises a disinfection box, a separation box, a storage box, a motor box and a cover plate, wherein the disinfection box and the separation box are located at the top of the interior of the cell screening body, the storage box and the motor box are located at the bottom of the interior of the cell screening body, the back of the cell screening body is hinged to the cover plate by a hinge, a rotor is installed in the middle of the separation box, a first test tube rack is provided on the top of the rotor, and a turntable is movably connected to the bottom of the rotor.
[0006] As a further solution of the utility model: ultraviolet lamps are fixedly installed around the inside of the disinfection box, and a second test tube rack is opened on the top of the disinfection box.
[0007] As a further solution of the utility model: a handle is fixedly installed on the front of the storage box.
[0008] As a further solution of the utility model: a motor is placed inside the motor box, a maintenance panel is provided on the front of the motor box, and a vent is provided on the side of the motor box.
[0009] As a further solution of the utility model: the maintenance plate is fixedly connected to the front side of the motor box by screws, and the top of the motor is fixedly connected to the turntable by a transmission shaft.
[0010] As a further solution of the utility model: a control panel is fixedly mounted on the front side of the cover plate.
[0011] As a further solution of the utility model: a lock is fixedly installed on the front side of the cell screening body.
[0012] By adopting the above technical solution, compared with the prior art, the beneficial effects of the utility model are:
[0013] 1. The utility model is connected with a transmission rod through a spline at the output end of the motor, the top of the transmission rod is fixedly connected to the turntable, and the inner wall of the turntable is threadedly connected to the bottom end of the rotor. Then, the motor is started to drive the transmission rod and the turntable to rotate, so that the rotor rotates at a high speed, and then the staff can place the test tube containing the cell suspension in the test tube rack opened inside the rotor, so as to achieve the effect of separating the cells in the cell suspension.
[0014] 2. The utility model fixes ultraviolet lamps around the inside of the disinfection box so that the inside of the disinfection box is in the disinfection light irradiation area, and then places the first test tube rack above the inner wall of the disinfection box and places the test tube in the test tube rack, thereby achieving the effect of rapid disinfection of the test tube in the disinfection area.
[0015] Other advantages, objectives and features of the present invention will be described in the following description to some extent, and will be apparent to those skilled in the art based on the following examination and study, or may be taught from the practice of the present invention to some extent. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] Figure 1 It is an overall schematic diagram of an embodiment of the utility model;
[0017] Figure 2 This is a schematic diagram of a disinfection box in an embodiment of the utility model;
[0018] Figure 3 This is a schematic diagram of a separation box in an embodiment of the utility model;
[0019] Figure 4 It is a schematic diagram of a control panel in an embodiment of the utility model.
[0020] In the figure: 1. cell screening body; 11. lock; 2. disinfection box; 21. second test tube rack; 22. ultraviolet lamp; 3. separation box; 31. rotor; 32. first test tube rack; 33. turntable; 4. storage box; 41. handle; 5. motor box; 51. motor; 6. cover. DETAILED DESCRIPTION
[0021] The specific implementation methods of the present invention are further described below in conjunction with the accompanying drawings. It should be noted that the description of these implementation methods is used to help understand the present invention, but does not constitute a limitation of the present invention. In addition, the technical features involved in each implementation method of the present invention described below can be combined with each other as long as they do not conflict with each other.
[0022] Example 1, please refer to the attached Figure 1 -Attached Figure 4 The cell screening device for stem cells includes a cell screening body 1, which includes a disinfection box 2, a separation box 3, a storage box 4, a motor box 5 and a cover plate 6. The disinfection box 2 and the separation box 3 are located at the top of the cell screening body 1, the storage box 4 and the motor box are located at the bottom of the cell screening body 1, the back of the cell screening body 1 is hinged to the cover plate 6, a rotor 31 is installed in the middle of the separation box 3, a first test tube rack 32 is provided on the top of the rotor 31, a turntable 33 is movably connected to the bottom of the rotor 31, and the rotor 31 and the turntable 33 are connected by threads.
[0023] In this embodiment, the back of the cell screening body 1 is hinged to the cover 6, and the cover 6 can be closed to prevent dust from entering the instrument when the instrument is not needed;
[0024] Ultraviolet lamps 22 are fixedly installed around the inside of the disinfection box 2, and a second test tube rack 21 is opened on the top of the disinfection box 2.
[0025] In this embodiment, by installing an ultraviolet lamp 22 inside the disinfection box 2, the instrument can be disinfected before and after use to prevent bacterial contamination;
[0026] A handle 41 is fixedly mounted on the front of the storage box 4 .
[0027] In this embodiment, a handle 41 is installed on the front of the storage box 4. When storage space is needed, the handle 41 is pulled to draw out the drawer.
[0028] A motor 51 is placed inside the motor box 5 , a maintenance panel is provided on the front of the motor box 5 , and a vent is provided on the side of the motor box 5 .
[0029] Specifically, a transmission rod is splinedly connected to the output end of the motor 51, the top of the transmission rod is fixedly connected to the turntable 33, and the inner wall of the turntable 33 is threadedly connected to the bottom end of the rotor 31. Then, the motor 51 is started to drive the transmission rod and the turntable 33 to rotate, so that the rotor 31 rotates at a high speed. Then, the staff can place the test tube containing the cell suspension in the test tube rack opened inside the rotor 31, so as to achieve the effect of separating the cells in the cell suspension.
[0030] Example 2, please refer to the attached Figure 1 -Attached Figure 4 The cell screening device for stem cells includes a cell screening body 1, which includes a disinfection box 2, a separation box 3, a storage box 4, a motor box 5 and a cover plate 6. The disinfection box 2 and the separation box 3 are located at the top of the cell screening body 1, the storage box 4 and the motor box are located at the bottom of the cell screening body 1, the back of the cell screening body 1 is hinged to the cover plate 6, a rotor 31 is installed in the middle of the separation box 3, a first test tube rack 32 is provided on the top of the rotor 31, a turntable 33 is movably connected to the bottom of the rotor 31, and the rotor 31 and the turntable 33 are connected by threads.
[0031] In this embodiment, the rotor 31 and the rotating disk 33 are threadedly connected so that the rotor can be disassembled or replaced after a rotor failure.
[0032] The maintenance plate is fixedly connected to the front of the motor box 5 by screws, and the top of the motor 51 is fixedly connected to the turntable 33 by a transmission shaft.
[0033] In this embodiment, the top of the motor 51 is fixedly connected to the turntable 33 via a transmission shaft, which can prevent the turntable 33 from slipping when running at high speed;
[0034] A control panel is fixedly mounted on the front of the cover plate 6 .
[0035] In this embodiment, the control board can control the speed, time, temperature and monitor the operating status;
[0036] A lock buckle 11 is fixedly mounted on the front side of the cell screening body 1 .
[0037] In this embodiment, when the cell screening body 1 is not working, a relatively closed environment is provided to reduce external interference and pollution.
[0038] Specifically, ultraviolet lamps 22 are fixedly installed around the interior of the disinfection box 2, so that the interior of the disinfection box 2 is in the disinfection light irradiation area, and then the first test tube rack 32 is placed above the inner wall of the disinfection box 2, and the test tube is placed in the test tube rack, so as to achieve the effect of rapid disinfection of the test tube in the disinfection area.
[0039] Working principle: First, place the test tube containing the cell stock solution in the first test tube rack 32, sterilize it with the ultraviolet lamp 22, and then place it in the second test tube rack 21, close the cover 6, start the motor 51 through the control panel, and drive the rotor 31 of the centrifuge to rotate at high speed. By controlling the speed and time of the centrifuge, different types of cells can be precipitated at different positions, thereby realizing cell screening and separation. At this point, the entire workflow is completed.
[0040] The above-mentioned front, back, left, right, top and bottom are all based on the figures in the specification. Figure 1 As a benchmark, according to the person's observation perspective, the side of the device facing the observer is defined as the front, the left side of the observer is defined as the left, and so on.
[0041] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the scope of protection of the present invention.
[0042] It should be noted that the equipment structure and drawings of the utility model mainly describe the principle of the utility model. In terms of the technology of the design principle, the settings of the power mechanism, power supply system and control system of the device are not fully described. On the premise that the technical personnel in this field understand the principle of the above-mentioned utility model, the details of its power mechanism, power supply system and control system can be clearly known. The control method of the application document is automatic control through a controller, and the control circuit of the controller can be realized by simple programming by technical personnel in this field.
[0043] The standard parts used therein can all be purchased from the market and can be customized according to the instructions and drawings. The specific connection methods of each part adopt conventional means such as mature bolts, rivets, welding, etc. in the prior art. The machinery, parts and equipment all adopt conventional models in the prior art, and the structures and principles of the components known to technical personnel in this field can be known by these technical personnel through technical manuals or through conventional experimental methods.
[0044] The embodiments of the present invention are described in detail above with reference to the accompanying drawings, but the present invention is not limited to the described embodiments.
[0045] For those skilled in the art, various changes, modifications, substitutions and variations can be made to these implementations without departing from the principle and spirit of the present invention, and they still fall within the protection scope of the present invention.
Claims
1. A cell screening device for stem cells, comprising a cell screening body (1), characterized in that: The cell screening body (1) comprises a disinfection box (2), a separation box (3), a storage box (4), a motor box (5) and a cover plate (6); the disinfection box (2) and the separation box (3) are located at the top of the cell screening body (1); the storage box (4) and the motor box (5) are located at the bottom of the cell screening body (1); the back of the cell screening body (1) and the cover plate (6) are hingedly connected by a hinge; a rotor (31) is installed in the middle of the separation box (3); a first test tube rack (32) is provided at the top of the rotor (31); a turntable (33) is movably connected to the bottom of the rotor (31); and the rotor (31) and the turntable (33) are connected by threads.
2. A cell screening device for stem cells according to claim 1, characterized in that: Ultraviolet lamps (22) are fixedly installed around the inside of the disinfection box (2), and a second test tube rack (21) is opened on the top of the disinfection box (2).
3. A cell screening device for stem cells according to claim 1, characterized in that: A handle (41) is fixedly mounted on the front of the storage box (4).
4. A cell screening device for stem cells according to claim 1, characterized in that: A motor (51) is placed inside the motor box (5), a maintenance panel is provided on the front of the motor box (5), and a ventilation hole is provided on the side of the motor box (5).
5. A cell screening device for stem cells according to claim 4, characterized in that: The maintenance plate is fixedly connected to the front of the motor box (5) by means of screws, and the top of the motor (51) is fixedly connected to the turntable (33) by means of a transmission shaft.
6. A cell screening device for stem cells according to claim 1, characterized in that: A control panel is fixedly mounted on the front side of the cover plate (6).
7. A cell screening device for stem cells according to claim 1, characterized in that: A lock buckle (11) is fixedly mounted on the front side of the cell screening body (1).
