CART cell filling and storing device with auxiliary cooling function

By adopting an adjustable placement plate and air discharge nozzle structure in the CART cell storage device, combined with the arc-shaped fixing plate and telescopic support rod, the problem of long cooling time and unstable fixation of the test tube is solved, and more efficient cooling and sealing is achieved Effect.

CN222216991UActive Publication Date: 2024-12-24SHANGHAI TELEBIO BIOMEDICAL
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Patent Information

Application Number
CN202420813589.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-19
Publication Date
2024-12-24
Estimated Expiration
2034-04-19

AI Technical Summary

Technical Problem

In the prior art, the cooling time and waste of refrigeration resources due to inflexible fixed positions during cooling.

Method used

A CART cell filling storage device with auxiliary cooling is designed, using an adjustable placement plate and air outlet nozzle structure, which moves the placement plate up and down through a motor, and combines the arc-shaped fixing plate and telescopic support rod to ensure that the test tube is The air outlet nozzle is in close contact to accelerate the cooling process; at the same time, it uses a sealing layer and a thermal insulation layer to reduce air loss and external interference.

Benefits of technology

It effectively shortens the cooling time, prevents the test tube from shaking and falling off, improves cooling efficiency and sealing performance, and reduces air loss and external interference.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an auxiliary cooling CART cell filling and storing device which comprises a box body, a box door is hinged to the front face of the box body through a hinge, a bearing plate is fixedly connected to the upper portion of the back face of the box body, a refrigerating machine is placed on the surface of the bearing plate, an air guide pipe is fixedly installed at the end of the refrigerating machine, and the air guide pipe is fixedly connected with the box door through a hinge. The air guide pipe penetrates through the back face of the box body to be installed in the box body, and an air outlet spray head is fixedly installed at the end of the air guide pipe. Through the arrangement of the lead screw, the placing plate is driven by the motor to move up and down and make close contact with the air outlet spray head, the cooling speed of cells in a test tube is increased, the time needed by the cooling step is shortened, the placing plate can move smoothly when ascending and descending through the telescopic supporting rod and the auxiliary supporting plate, and the cooling efficiency is improved. The arc-shaped fixing plate can fix and clamp the test tubes, so that the situation that the test tubes burst out and are damaged due to careless falling when people carry the box body is avoided, and meanwhile, shaking can also be avoided in the lifting process of the placing plate.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell storage devices, and in particular to a CART cell filling and storage device with auxiliary cooling. Background Art

[0002] CAR-T is chimeric antigen receptor T cell immunotherapy. T cells are a type of cell in the human body that can produce an immune response to viruses. They are generally used to treat tumor diseases. After production, they will be placed in a storage device for cooling and storage.

[0003] The existing technology has the following problems:

[0004] In the prior art, when cooling test tubes storing cell medicines, the test tubes are fixed in a storage box and cannot be flexibly adjusted according to the position of the cooling mechanism. If the distance is too far, the time required for the cooling step will be increased, thereby increasing the waste of refrigeration resources. Utility Model Content

[0005] In view of the problems in the related technology, the utility model proposes a CART cell filling and storage device with auxiliary cooling to overcome the above-mentioned technical problems existing in the existing related technology.

[0006] To this end, the specific technical solutions adopted by the utility model are as follows:

[0007] A CART cell filling and storage device with auxiliary cooling comprises a box body, wherein the front side of the box body is hinged with a box door by a hinge, a bearing plate is fixedly connected to the upper part of the back side of the box body, a refrigerator is placed on the surface of the bearing plate, an air duct is fixedly installed on the end of the refrigerator, the air duct passes through the back side of the box body and is installed inside the box body, an air outlet nozzle is fixedly installed on the end of the air duct, a motor is fixedly installed at the rear part of the top of the box body, a placement plate is arranged inside the box body, a placement groove is opened on the surface of the placement plate, a screw rod is arranged at the rear part of the surface of the placement plate, the screw rod passes through the placement plate and extends to the bottom of the box body, an auxiliary support plate is fixedly connected to the bottom of the placement plate, a telescopic support rod is fixedly connected to the bottom of the auxiliary support plate, and the length of the auxiliary support plate is approximately the same as the length of the placement plate.

[0008] Preferably, a return spring is fixedly connected to the inner wall of the placement groove, and an arc-shaped fixing plate is fixedly connected to the end of the return spring. The test tube can be fixedly clamped by the arc-shaped fixing plate to prevent the test tube from accidentally falling off when people carry the box and causing damage to the test tube. At the same time, shaking can also be avoided during the lifting and lowering of the placement plate.

[0009] Preferably, an anti-skid pad is bonded to the surface of the arc-shaped fixing plate, and the anti-skid pad is made of rubber material. The provision of the anti-skid pad increases the contact friction between the arc-shaped fixing plate and the test tube, which helps to improve the fixing effect.

[0010] Preferably, a sealing layer is bonded to the back edge of the box door, and the sealing layer is a rubber sealing strip made of polytetrafluoroethylene. The sealing layer is provided to increase the sealing performance between the box body and the door after closing, thereby reducing the entry of outside air and dust into the box body.

[0011] Preferably, the inner wall of the box is filled with an insulation layer, and the insulation layer is a low-temperature insulation board made of polyurethane material. The insulation layer can keep the cold air inside the box warm and reduce the loss of cold air.

[0012] Preferably, a temperature and humidity detector is fixedly installed at the upper part of the interior of the box, and a display component is provided on the front of the box door. The temperature and humidity detector is electrically connected to the display component. By using the set temperature and humidity detector in conjunction with the display component, people can conveniently know the temperature and humidity conditions in the box at any time, thereby avoiding damage to cell drug test tubes due to improper storage under temperature and humidity conditions.

[0013] Preferably, feet are provided at the four corners of the bottom of the box, the bottom area of ​​the feet is larger than the top, and wear-resistant pads are bonded to the bottom surface of the feet. By providing feet of special shape, the box can be placed more stably, and the provision of wear-resistant pads prevents the feet from directly contacting the ground and causing wear.

[0014] The beneficial effects of the utility model are:

[0015] 1. The auxiliary cooling CART cell filling and storage device, through the provided screw rod, drives the placement plate up and down under the drive of the motor, and comes into close contact with the air outlet nozzle, thereby accelerating the cooling speed of the cells in the test tube and reducing the time required for the cooling step. The telescopic support rod and the auxiliary support plate can make the placement plate move more smoothly when it is raised and lowered. The arc-shaped fixing plate can fix and clamp the test tube to prevent the test tube from falling off accidentally when people are carrying the box, causing damage to the test tube, and at the same time, it can also prevent shaking during the raising and lowering process of the placement plate.

[0016] 2. The auxiliary cooling CART cell filling and storage device can keep the cold air inside the box warm by providing a sealing layer and a thermal insulation layer, thereby reducing the loss of cold air and preventing outside air and dust from entering the box. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0018] Figure 1 It is a schematic diagram of the internal structure of the utility model;

[0019] Figure 2 It is a schematic diagram of the external structure of the utility model;

[0020] Figure 3 It is an enlarged structural schematic diagram of the placement plate of the utility model;

[0021] Figure 4 It is a schematic diagram of the internal structure of the inner wall of the box body of the present utility model.

[0022] In the figure: 1. box body; 2. box door; 3. sealing layer; 4. motor; 5. screw rod; 6. placement plate; 7. telescopic support rod; 8. auxiliary support plate; 9. refrigerator; 10. air guide duct; 11. air outlet nozzle; 12. placement slot; 13. reset spring; 14. arc fixing plate; 15. insulation layer. DETAILED DESCRIPTION

[0023] To further illustrate each embodiment, the present invention provides drawings, which are part of the disclosure of the present invention and are mainly used to illustrate the embodiments. They can be used in conjunction with the relevant descriptions in the specification to explain the operating principles of the embodiments. With reference to these contents, ordinary technicians in the field should be able to understand other possible implementation methods and advantages of the present invention. The components in the figures are not drawn to scale, and similar component symbols are generally used to represent similar components.

[0024] According to an embodiment of the utility model, a CART cell filling and storage device with auxiliary cooling is provided.

[0025] Embodiment 1;

[0026] like Figure 1-Figure 4As shown, the CART cell filling and storage device with auxiliary cooling according to the embodiment of the utility model includes a box body 1, the front of the box body 1 is hinged with a box door 2 through a hinge, a bearing plate is fixedly connected to the upper back of the box body 1, a refrigerator 9 is placed on the surface of the bearing plate, and an air duct 10 is fixedly installed at the end of the refrigerator 9. The air duct 10 passes through the back of the box body 1 and is installed inside it, and an air outlet nozzle 11 is fixedly installed at the end of the air duct 10. A motor 4 is fixedly installed at the rear of the top of the box body 1, a placement plate 6 is provided inside the box body 1, a placement groove 12 is opened on the surface of the placement plate 6, and a screw rod 5 is provided at the rear of the surface of the placement plate 6, which passes through the placement plate 6 and extends to the bottom of the box body 1, and an auxiliary support plate 8 is fixedly connected to the bottom of the placement plate 6, and a telescopic support rod 7 is fixedly connected to the bottom of the auxiliary support plate 8, and the length of the auxiliary support plate 8 is approximately the same as the length of the placement plate 6.

[0027] In this embodiment, a return spring 13 is fixedly connected to the inner wall of the placement groove 12, and an arc-shaped fixing plate 14 is fixedly connected to the end of the return spring 13. The arc-shaped fixing plate 14 can be set to fix and clamp the test tube to prevent the test tube from accidentally falling off when people carry the box 1 and causing damage. At the same time, shaking can also be avoided during the lifting and lowering of the placement plate 6.

[0028] In this embodiment, an anti-skid pad is bonded to the surface of the arc-shaped fixing plate 14. The anti-skid pad is made of rubber material. The provision of the anti-skid pad increases the contact friction between the arc-shaped fixing plate 14 and the test tube, which helps to improve the fixing effect.

[0029] In this embodiment, a sealing layer 3 is bonded to the back edge of the box door 2. The sealing layer 3 is a rubber sealing strip made of polytetrafluoroethylene. The sealing layer 3 is provided to increase the sealing performance between the box body 1 and the box door 2 after closing, thereby reducing the entry of outside air and dust into the box body 1.

[0030] In this embodiment, the inner wall of the box 1 is filled with an insulation layer 15, and the insulation layer 15 is a low-temperature insulation board made of polyurethane. The insulation layer 15 can keep the cold air inside the box 1 warm and reduce the loss of cold air.

[0031] Embodiment 2:

[0032] On the basis of Example 1, a preferred embodiment of the auxiliary cooling CART cell filling and storage device provided by the utility model is as follows: Figures 1 to 4 As shown:

[0033] In this embodiment, a temperature and humidity detector is fixedly installed at the upper part of the interior of the box body 1, and a display component is provided on the front of the box door 2. The temperature and humidity detector is electrically connected to the display component. By using the set temperature and humidity detector in conjunction with the display component, people can conveniently know the temperature and humidity conditions in the box body 1 at any time, thereby preventing the cell drug test tubes from being damaged due to improper storage under temperature and humidity conditions.

[0034] In this embodiment, supporting feet are provided at the four corners of the bottom of the box 1. The bottom area of ​​the supporting feet is larger than the top thereof. Wear-resistant pads are bonded to the bottom surface of the supporting feet. By providing supporting feet of special shapes, the box 1 is placed more stably. The provision of wear-resistant pads prevents the supporting feet from directly contacting the ground and causing wear.

[0035] In order to facilitate understanding of the above technical solution of the present invention, the working principle or operation method of the present invention in the actual process is described in detail below.

[0036] In actual application, the placement plate 6 can move up and down by rotating the screw rod 5 driven by the motor 4, so that the test tube in the placement slot 12 can be in close contact with the air outlet nozzle 11, accelerating the cooling speed of the cells in the test tube and reducing the time required for the cooling step. The telescopic support rod 7 and the auxiliary support plate 8 can make the placement plate 6 more stable when lifting and lowering. Since the test tube is clamped and fixed by the arc-shaped fixing plate 14, the influence of the tiny shaking force generated during the lifting process on the test tube is effectively reduced. The setting of the sealing layer 3 and the thermal insulation layer 15 can keep the cold air inside the box 1 warm and reduce the loss of cold air.

[0037] In summary, with the aid of the above-mentioned technical scheme of the utility model, through the arranged screw rod 5, the placement plate 6 is moved up and down under the drive of the motor 4, and is in close contact with the air outlet nozzle 11, thereby accelerating the cooling speed of the cells in the test tube and reducing the time required for the cooling step. The telescopic support rod 7 and the auxiliary support plate 8 can make the placement plate 6 move more smoothly when it is raised and lowered. The arc-shaped fixing plate 14 can fix and clamp the test tube to prevent the test tube from accidentally falling off when people carry the box 1 and causing the test tube to burst and be damaged. At the same time, shaking can also be avoided during the lifting and lowering process of the placement plate 6. The setting of the sealing layer 3 and the thermal insulation layer 15 can keep the cold air inside the box 1 warm, reduce the loss of cold air, and prevent outside air and dust from entering the box 1.

[0038] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A CART cell filling and storage device with auxiliary cooling, comprising a box (1), characterized in that: The front of the box (1) is hinged with a box door (2) via a hinge, the back of the box (1) is fixedly connected to a bearing plate, a refrigerator (9) is placed on the surface of the bearing plate, an air duct (10) is fixedly installed at the end of the refrigerator (9), the air duct (10) passes through the back of the box (1) and is installed inside the box, an air outlet nozzle (11) is fixedly installed at the end of the air duct (10), a motor (4) is fixedly installed at the rear of the top of the box (1), and the box (1) is fixedly installed with a motor (4). A placement plate (6) is arranged inside the box (1), a placement groove (12) is provided on the surface of the placement plate (6), a screw rod (5) is arranged at the rear of the surface of the placement plate (6), the screw rod (5) passes through the placement plate (6) and extends to the bottom of the box body (1), the bottom of the placement plate (6) is fixedly connected to an auxiliary support plate (8), the bottom of the auxiliary support plate (8) is fixedly connected to a telescopic support rod (7), and the length of the auxiliary support plate (8) is the same as the length of the placement plate (6).

2. The CART cell filling and storage device with auxiliary cooling according to claim 1, characterized in that: A return spring (13) is fixedly connected to the inner wall of the placement groove (12), and an arc-shaped fixing plate (14) is fixedly connected to the end of the return spring (13).

3. The CART cell filling and storage device with auxiliary cooling according to claim 2, characterized in that: The surface of the arc-shaped fixing plate (14) is bonded with an anti-skid pad, which is made of rubber material.

4. The CART cell filling and storage device with auxiliary cooling according to claim 1, characterized in that: A sealing layer (3) is bonded to the back edge of the door (2), and the sealing layer (3) is a rubber sealing strip made of polytetrafluoroethylene.

5. The CART cell filling and storage device with auxiliary cooling according to claim 1, characterized in that: The interior of the inner wall of the box body (1) is filled with a heat-insulating layer (15), and the heat-insulating layer (15) is a low-temperature heat-insulating board made of polyurethane material.

6. The CART cell filling and storage device with auxiliary cooling according to claim 1, characterized in that: A temperature and humidity detector is fixedly installed at the upper part of the interior of the box body (1), a display component is arranged on the front of the box door (2), and the temperature and humidity detector is electrically connected to the display component.

7. The CART cell filling and storage device with auxiliary cooling according to claim 1, characterized in that: Support feet are arranged at the four corners of the bottom of the box body (1); the bottom area of ​​the support feet is larger than the top area; and wear-resistant pads are bonded to the bottom surfaces of the support feet.