Anti-cancer drug intermediate distillation device

Abstract

The utility model relates to the technical field of medicine distillation and purification, and discloses an anti-cancer medicine intermediate distillation device which comprises a condensation box, the upper surface of the condensation box is fixedly connected with a condensation action plate, and the condensation action plate is connected with a condensate water through pipe, a condensate water inlet pipe and a condensate water outlet pipe. The side surface of the condensing box is provided with a sliding groove, a sweeping scraping rod and an operating handle. The condensation plate is contacted with distillation steam, and the condensate water through pipe, the condensate water inlet pipe and the condensate water outlet pipe act on the condensation plate to achieve low temperature and take away heat. After the steam is condensed, the operating handle is operated to enable the sweeping scraping rod to move on the sliding groove, condensed steam water drops are scraped down, and the condensed steam water drops fall onto the lower surface of the condensing box and then are collected into the collecting box through the collecting groove to be collected. And the risk that steam is exposed in the air is avoided, the condensation effect is achieved, the overall condensation speed is further increased, collection is conducted in time after rapid condensation, the risk that intermediate products react is further avoided, and the yield is increased.

Description

Technical Field

[0001] The utility model belongs to the technical field of drug distillation and purification, and specifically relates to an anticancer drug intermediate distillation device. Background Art

[0002] Distillation is a thermodynamic separation process that uses the different boiling points of components in a mixed liquid or liquid-solid system to evaporate the lower-boiling-point substance, thereby separating the lower-boiling-point substance from the mixture and achieving purification effects. Distillation can purify substances efficiently and quickly, and by controlling the temperature, different substances can be purified. Therefore, a single distillation device can process multiple substances, not just one, offering high flexibility.

[0003] A search of the application CN214634083U discloses a continuous extraction and distillation device for the production of antiviral and detoxifying granular drugs, comprising a distillation tank body, a feeding and discharging device arranged on the distillation tank body, a distillation plate fixedly arranged inside the distillation tank body, a steam device fixedly arranged inside the distillation tank body, an air outlet pipe fixedly arranged at the upper end of the distillation tank body, a condenser fixedly arranged at the right end of the distillation tank body, a liquid collection box fixedly arranged at the right end of the distillation tank body, a drug collection chamber arranged at the lower part of the distillation tank body, a discharge port fixedly arranged at the lower end of the distillation tank body, and a tripod fixedly arranged at the lower end of the distillation tank body. In the present utility model, continuous feeding of drugs is achieved by arranging a feeding auger, and the granular drugs are evenly spread on the distillation plate by placing a stripping plate to achieve sufficient distillation of the drugs, and continuous discharging of drugs is achieved by the stripping plate and the spiral discharging trough arranged on the distillation plate.

[0004] However, the inventors have discovered that this technical solution still has at least the following defects:

[0005] First, drugs are organic substances, especially when used as intermediates in reactions. They are easily exposed to oxygen in the air and react with it. Therefore, even in a sealed environment, they need to be collected as quickly as possible to reduce condensation time.

[0006] Second, for distillation, in addition to lowering the temperature, it is also necessary to expand the contact area.

[0007] In view of this, the present utility model is proposed. Utility Model Content

[0008] In order to solve the above technical problems, the basic concept of the technical solution adopted by the present invention is:

[0009] A device for distilling an anti-cancer drug intermediate, wherein the upper surface of the condensation box is fixedly connected to a condensation action plate, the side surface of the condensation action plate is plugged with multiple condensation water pipes, the side surface of the condensation water pipe is plugged with a condensation water inlet pipe, the side surface of the condensation water pipe opposite to the condensation water inlet pipe is plugged with a condensation water outlet pipe, a sliding groove is provided at the upper end of the side surface of the condensation box, a sweeping scraper is plugged into the sliding groove through the hole groove, the upper surface of the sweeping scraper is fixedly connected to multiple operating handles, the bottom of the condensation box is provided with multiple collection grooves, and the side surfaces of the collection grooves are fixedly connected to multiple collection boxes.

[0010] As a preferred embodiment of the present invention, a steam inlet pipe is inserted into the lower surface of the condensing box, and a distillation raw liquid storage box is inserted into the end of the steam inlet pipe opposite to the condensing box.

[0011] As a preferred embodiment of the present invention, the lower surface of the condensation box is fixedly connected to a water bath heating box, the side surface of the water bath heating box is plugged with a heating rod, and the side surface of one end of the heating rod relative to the water bath heating box is fixedly connected to a low-voltage power supply device.

[0012] As a preferred embodiment of the present invention, a distillation stock liquid inlet pipe is inserted into the side surface of the distillation stock liquid placement box.

[0013] As a preferred embodiment of the present invention, a drainage hole is provided on the lower surface of the water bath heating box, and a sealing plug-in plate is plugged into the side surface of the water bath heating box.

[0014] As a preferred embodiment of the present invention, a wastewater storage box is fixedly connected to the lower surface of the water bath heating box.

[0015] As a preferred embodiment of the present invention, a wastewater discharge valve is fixedly connected to the lower surface of the wastewater storage box, and a valve water blocking block is provided on the lower surface of the wastewater discharge valve.

[0016] As a preferred embodiment of the present invention, a plurality of device brackets are fixedly connected to the side surface of the wastewater storage box.

[0017] Compared with the prior art, the present invention has the following beneficial effects:

[0018] The utility model utilizes a condensation box to contain the distilled steam, utilizes a condensation action plate to contact the distilled steam, utilizes a condensation water inlet pipe to connect the condensation water, and continuously maintains the condensation water plate at a low temperature through multiple condensation water pipes to take away the heat, and then utilizes a condensation water outlet pipe to pass the condensation water away. After the steam is condensed, the operating handle is operated to move the sweeping scraper rod on the sliding groove. Since the sweeping scraper rod is close to the lower surface of the condensation action plate, the condensed steam droplets will be scraped off during movement, and after falling on the lower surface of the condensation box, they will be collected in the collection box through the collection groove for collection.

[0019] The condensation box eliminates the risk of steam being exposed to air, while the condensation plate connects the condensate pipe, condensate inlet pipe, and condensate outlet pipe to itself. This not only facilitates condensation but also utilizes the plate's large surface area to further increase the overall condensation speed, thereby avoiding the risk of further reactions with intermediate products. After condensation, a sweeping scraper removes the condensed droplets, which are then collected in a collection groove into the collection box. This ensures rapid condensation and timely collection, further minimizing the risk of intermediate product reactions and increasing yield. This entire process is completed quickly and is simple and convenient to operate, significantly improving operator productivity.

[0020] The distillation stock liquid storage box is used to place the stock liquid to be distilled. The heated gas then enters the condensation box directly through the steam inlet pipe. This realizes the integration of the entire device from heating to condensation, avoiding the entry of air and other impurities that affect condensation during the conversion process. Operators can use a water bath heating box to store a certain amount of water, and then use the energy provided by the low-voltage power supply device to drive the heating rod to heat the water. Because this is a pharmaceutical, water bath heating is the most appropriate heating method. Using a heating rod and a low-voltage power supply device for heating is very easy and fast, and the temperature can be adjusted better and faster. Water bath heating will not cause the temperature to rise and fall too quickly, and is relatively stable.

[0021] The distillate storage box allows the distillate to be fed into the distillate inlet pipe, eliminating unnecessary steps and saving time and effort. The operator uses the drain hole to drain and replace the water after the water bath is heated. The sealing plate acts as a barrier to prevent water flow during normal operation, maintaining the water bath's heating cycle and preventing leaks. The drain hole and sealing plate allow for more flexible control of the water bath heating process. The wastewater storage box holds wastewater from the water bath, preventing it from escaping and affecting the surrounding operating environment.

[0022] Operators regularly drain the wastewater heated in the water bath through the wastewater discharge valve, which is then covered with a valve water block to prevent it from being affected by daily use. The entire device is supported by a bracket to provide stability and isolate it from the ground to prevent rust caused by long-term direct contact.

[0023] The specific embodiments of the present invention will be described in further detail below with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In the attached figure:

[0025] Figure 1 This is a side view of the overall structure of the utility model;

[0026] Figure 2 This is a schematic diagram of the back structure of the overall device of the utility model;

[0027] Figure 3 This is a schematic diagram of the cross-sectional structure of the water bath heating box of the present invention;

[0028] Figure 4 This is a schematic diagram of the detailed structure of the collecting groove of the utility model;

[0029] Figure 5 This is a detailed structural diagram of the heating rod of the utility model;

[0030] Figure 6 This is a detailed structural diagram of the condensation plate of the utility model.

[0031] In the figure: 1. Condensate box; 2. Condensation action plate; 3. Condensate pipe; 4. Condensate inlet pipe; 5. Condensate outlet pipe; 6. Sliding groove; 7. Sweeping scraper; 8. Operating handle; 9. Steam inlet pipe; 10. Collecting groove; 11. Collecting box; 12. Water bath heating box; 13. Wastewater storage box; 14. Distillate stock storage box; 15. Distillate stock inlet pipe; 16. Heating rod; 17. Drain hole; 18. Sealing plug-in plate; 19. Low-voltage power supply device; 20. Wastewater discharge valve; 21. Valve water block; 22. Device bracket. DETAILED DESCRIPTION

[0032] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. The following embodiments are used to illustrate the present invention.

[0033] like Figures 1 to 6As shown, a distillation device for an anti-cancer drug intermediate is provided, wherein a condensation plate 2 is fixedly connected to the upper surface of a condensation box 1, a plurality of condensation water pipes 3 are inserted into the side surface of the condensation water pipes 3, a condensation water inlet pipe 4 is inserted into the side surface of the condensation water pipes 3, a condensation water outlet pipe 5 is inserted into the side surface of one end of the condensation water pipes 3 opposite to the condensation water inlet pipe 4, a sliding groove 6 is provided at the upper end of the side surface of the condensation box 1, a sweeping scraper 7 is inserted into the sliding groove 6 through the hole groove provided, a plurality of operating handles 8 are fixedly connected to the upper surface of the sweeping scraper 7, a plurality of collecting grooves 10 are provided at the bottom of the condensation box 1, and a plurality of collecting boxes 11 are fixedly connected to the side surface of the collecting groove 10. In this configuration, the operator uses a condensation box 1 to contain the distilled steam, a condensation plate 2 to contact the distilled steam, a condensate inlet pipe 4 to connect the condensate, and multiple condensate pipes 3 to continuously maintain the condensation plate 2 at a low temperature, removing heat. The condensate is then discharged through a condensate outlet pipe 5. After the steam condenses, the operator operates an operating handle 8 to move a sweeping scraper 7 along a sliding groove 6. Because the sweeping scraper 7 is in close contact with the lower surface of the condensation plate 2, it scrapes off condensed steam droplets during movement. These droplets fall onto the lower surface of the condensation box 1 and are collected by a collection groove 10 into a collection box 11 for collection. The condensation box 1 avoids the risk of steam being exposed to air, while the condensation plate 2 connects the condensate pipes 3, condensate inlet pipe 4, and condensate outlet pipe 5 to itself. This not only provides condensation, but also utilizes the large surface area of ​​the condensation plate 2 to further increase the overall condensation rate, thereby avoiding the risk of further reactions of intermediate products. After condensation, the sweeping scraper 7 scrapes off the condensed droplets, which are collected in the collection box 11 through the collection groove 10, thereby achieving timely collection after rapid condensation, further avoiding the risk of intermediate product reaction, and increasing the yield. In the above overall process, all are completed in a short period of time, and the operation is simple and convenient, which greatly improves the production efficiency of the operator.

[0034] like Figures 1 to 6 As shown, in this embodiment, a steam inlet pipe 9 is connected to the lower surface of the condenser tank 1, and a distillation stock liquid storage box 14 is connected to the end of the steam inlet pipe 9 opposite the condenser tank 1. In this configuration, the distillation stock liquid storage box 14 is used to store the stock liquid to be distilled. The heated gas then enters the condenser tank 1 directly through the steam inlet pipe 9, achieving an integrated device from heating to condensation, preventing the entry of impurities such as air during the conversion process and affecting condensation.

[0035] like Figures 1 to 6As shown, further, a water bath heating box 12 is fixedly connected to the lower surface of the condensation box 1, a heating rod 16 is plugged into the side surface of the water bath heating box 12, and a low-voltage power supply device 19 is fixedly connected to the side surface of the heating rod 16 opposite to the water bath heating box 12. In this configuration, the operator can use the water bath heating box 12 to store a certain amount of water, and then use the energy provided by the low-voltage power supply device 19 to drive the heating rod 16 to heat the water. Because the medicine is a drug, water bath heating is the most suitable heating method. Heating with the heating rod 16 and the low-voltage power supply device 19 is very easy and fast, and the temperature can be adjusted better and faster. Water bath heating will not cause the temperature to rise or fall too quickly, and is relatively stable.

[0036] like Figures 1 to 6 As shown, further, a distillate stock liquid inlet pipe 15 is plugged into the side surface of the distillate stock liquid placement box 14. In this arrangement, the distillate stock liquid placement box 14 can be used to input the distillate stock liquid into the distillate stock liquid inlet pipe 15 without doing extra operations, saving time and effort.

[0037] like Figures 1 to 6 As shown, the lower surface of the water bath heating box 12 is provided with a drain hole 17, and the side surface of the water bath heating box 12 is plugged with a sealing plate 18. In this arrangement, the operator can use the drain hole 17 to drain and replace the water after the water bath is heated, while the sealing plate 18 serves as a water blocker under normal circumstances to maintain the completion of the water bath heating and prevent water leakage. The drain hole 17 and the sealing plate 18 can be used to more flexibly control the water bath heating process.

[0038] like Figures 1 to 6 As shown, further, a wastewater receiving box 13 is fixedly connected to the lower surface of the water bath heating box 12. In this setting, the operator uses the wastewater receiving box 13 to contain the wastewater after the water bath heating to prevent it from flowing around and affecting the surrounding operating environment.

[0039] like Figures 1 to 6 As shown, a wastewater discharge valve 20 is fixedly connected to the lower surface of the wastewater storage box 13, and a valve water block 21 is provided on the lower surface of the wastewater discharge valve 20. In this arrangement, the operator uses the wastewater discharge valve 20 to regularly discharge the wastewater heated in the water bath, and then uses the valve water block 21 to cover it to avoid affecting daily use.

[0040] like Figures 1 to 6 As shown, further, a plurality of device brackets 22 are fixedly connected to the side surface of the wastewater storage box 13. In this setting, the device brackets 22 are used to support the entire device to achieve a stable effect, and the device is also isolated from the ground to avoid rust caused by long-term direct contact.

[0041] The working principle of the anticancer drug intermediate distillation device of this embodiment is as follows: a condensation box 1 is used to contain the distillation steam, a condensation plate 2 is used to contact the distillation steam, a condensation water inlet pipe 4 is used to connect the condensation water, and a plurality of condensation water pipes 3 are used to continuously maintain the condensation plate 2 at a low temperature to remove heat. The condensation water is then discharged through a condensation water outlet pipe 5. After the steam condenses, an operating handle 8 is operated to move a sweeping scraper 7 along a sliding groove 6. Since the sweeping scraper 7 is close to the lower surface of the condensation plate 2, it scrapes off the condensed steam droplets during movement. The sweeping scraper 7 falls on the lower surface of the condensation box 1 and is collected by a collection groove 10 in a collection box 11 for collection. The condensation box 1 avoids the risk of steam being exposed to the air, and the condensation plate 2 is connected to the condensation water pipe 3, condensation water inlet pipe 4, and condensation water outlet pipe 5. This not only performs the condensation function, but also utilizes the large surface area of ​​the condensation plate 2 to further increase the overall condensation speed, thereby avoiding the risk of further reaction of the intermediate product. After condensation, the sweeping scraper 7 scrapes off the condensed droplets, which are collected in the collection box 11 through the collection groove 10, thereby achieving timely collection after rapid condensation, further avoiding the risk of intermediate product reaction, and increasing the yield. In the above overall process, all are completed in a short period of time, and the operation is simple and convenient, which greatly improves the production efficiency of the operator.

Claims

1. An anticancer drug intermediate distillation device, comprising a condenser (1), characterized in that: The upper surface of the condensation box (1) is fixedly connected to a condensation action plate (2), the side surface of the condensation action plate (2) is plugged with a plurality of condensation water pipes (3), the side surface of the condensation water pipes (3) is plugged with a condensation water inlet pipe (4), and the side surface of one end of the condensation water pipe (3) opposite to the condensation water inlet pipe (4) is plugged with a condensation water outlet pipe (5), a sliding groove (6) is provided at the upper end of the side surface of the condensation box (1), a sweeping scraper (7) is plugged into the sliding groove (6) through the hole groove, and a plurality of operating handles (8) are fixedly connected to the upper surface of the sweeping scraper (7), a plurality of collecting grooves (10) are provided at the bottom of the condensation box (1), and a plurality of collecting boxes (11) are fixedly connected to the side surface of the collecting groove (10).

2. The anticancer drug intermediate distillation device according to claim 1, characterized in that: A steam inlet pipe (9) is inserted into the lower surface of the condensing box (1), and a distillation raw liquid storage box (14) is inserted into the end of the steam inlet pipe (9) opposite to the condensing box (1).

3. The anticancer drug intermediate distillation device according to claim 1, characterized in that: The lower surface of the condensation box (1) is fixedly connected to a water bath heating box (12), a heating rod (16) is plugged into the side surface of the water bath heating box (12), and a low-voltage power supply device (19) is fixedly connected to the side surface of one end of the heating rod (16) relative to the water bath heating box (12).

4. The anticancer drug intermediate distillation device according to claim 2, characterized in that: A distillation stock liquid inlet pipe (15) is inserted into the side surface of the distillation stock liquid storage box (14).

5. The anticancer drug intermediate distillation device according to claim 3, characterized in that: A drainage hole (17) is provided on the lower surface of the water bath heating box (12), and a sealing plug plate (18) is plugged into the side surface of the water bath heating box (12).

6. The anticancer drug intermediate distillation device according to claim 3, characterized in that: A wastewater storage box (13) is fixedly connected to the lower surface of the water bath heating box (12).

7. The anticancer drug intermediate distillation device according to claim 6, characterized in that: A wastewater discharge valve (20) is fixedly connected to the lower surface of the wastewater storage box (13), and a valve water blocking block (21) is provided on the lower surface of the wastewater discharge valve (20).

8. The anticancer drug intermediate distillation device according to claim 6, characterized in that: A plurality of device brackets (22) are fixedly connected to the side surface of the wastewater storage box (13).

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