Chicken embryo antigen extraction device

Abstract

The utility model discloses a chick embryo antigen extraction device which comprises an extraction needle mechanism, the extraction needle mechanism comprises a crude extraction needle tube, and the side wall of the crude extraction needle tube is communicated with a fine extraction needle tube assembly; the fine extraction needle tube assembly comprises a long hose which is assembled and communicated with the coarse extraction needle tube, and the long hose is communicated with a fine extraction needle; the crude extraction needle tube is communicated with an extraction tube through a connecting piece; the extraction tube is communicated with a compressed air tube, in the extraction process, when the crude extraction needle tube or the fine extraction needle is blocked, the compressed air tube is communicated with an air pump, and the crude extraction needle tube and the fine extraction needle are dredged by pumping compressed air; and the discharge end of the extraction pipe is communicated with a collector for collecting samples. According to the device, in the chick embryo antigen extraction process, the technical problem of needle tube blockage can be effectively solved, and the extraction efficiency is high.

Description

Technical Field

[0001] The utility model belongs to the technical field of chicken embryo antigen extraction, in particular to a chicken embryo antigen extraction device. Background Art

[0002] Chicken embryos are chicken embryos. Chicken embryo antigens are obtained by biological means during the development of chicken embryos, and vaccines are obtained by extracting antigens. Therefore, the extraction of chicken embryo antigens is a very important method in the vaccine production process.

[0003] Specifically, in the process of obtaining chicken embryo antigens, steps such as disinfecting the chicken embryo air chamber, cutting off part of the eggshell in the air chamber, cutting the membrane, and harvesting the chicken embryo antigens are required. Among them, the step of harvesting the chicken embryo antigen requires pressing the chicken embryo to one side with tweezers in one hand and holding a syringe in the other hand to suck out the chicken embryo antigen through the needle on the syringe.

[0004] Therefore, the above operation steps are not only difficult to operate in the operation process, but also require holding the syringe for a long time. During the operation of the syringe, it is difficult to control the strength and the chicken embryo antigen cannot be fully sucked out.

[0005] At the same time, this method is easy to collect impurities such as egg white, egg yolk, and chicken feathers into the antigen, and the needle will be blocked during the harvesting process, which is difficult to clean. Therefore, when the syringe needle is blocked, it is necessary to replace the needle or replace the syringe. Obviously, this method requires the syringe to be pulled out of the chicken embryo and then inserted again. This method is not only cumbersome, but also during the insertion and removal process, the tissue fluid in the chicken embryo is easy to overflow, causing contamination. In severe cases, it can cause infection of other normal chicken embryos. Utility Model Content

[0006] Based on the above background, the purpose of the utility model is to provide a chicken embryo antigen extraction device.

[0007] In order to achieve the above objectives, the utility model adopts the following technical solutions:

[0008] A chicken embryo antigen extraction device comprises an extraction needle mechanism, wherein the extraction needle mechanism comprises a coarse extraction needle tube, and a fine extraction needle tube assembly is connected to the side wall of the coarse extraction needle tube;

[0009] The thin extraction needle tube assembly includes a long hose connected to the thick extraction needle tube, and the long hose is connected to the thin extraction needle;

[0010] The crude extraction needle tube is connected to the extraction tube via a connector;

[0011] The extraction tube is connected with a compressed air tube. During the extraction process, when the coarse extraction needle tube or the fine extraction needle is blocked, the compressed air tube is connected to the air pump, and compressed air is pumped in to clear the coarse extraction needle tube and the fine extraction needle.

[0012] The discharge end of the extraction tube is connected to a collector for collecting samples.

[0013] Preferably, the crude extraction needle tube is equipped with a needle filter sleeve, and the needle filter sleeve is provided with a plurality of filter holes.

[0014] Preferably, the connecting member comprises a connecting seat connected to the crude extraction needle tube, and the connecting seat is provided with a groove body connected to the crude extraction needle tube;

[0015] The bottom of the tank is provided with a liquid inlet hole connected to the coarse extraction needle tube;

[0016] The connecting piece also includes a threaded seat connected to the extraction pipe, and the threaded seat is provided with a through hole connected to the extraction pipe;

[0017] The threaded seat is threadedly connected in the groove body.

[0018] Preferably, an adaptive filter screen is provided in the tank body.

[0019] Preferably, the extraction tube is connected to a lower connecting tube, and the lower connecting tube is connected to a cleaning container.

[0020] Preferably, the lower connecting pipe is equipped with a first valve;

[0021] The compressed air pipe is equipped with a second valve.

[0022] Preferably, the extraction pipe is equipped with a third valve and a fourth valve;

[0023] The third valve controls the liquid inlet into the extraction pipe, and the fourth valve controls the liquid inlet into the collector.

[0024] Preferably, the crude extraction needle tube is equipped with a connector, and the long hose is connected to the connector.

[0025] The utility model has the following beneficial effects:

[0026] 1. By designing a thin extraction needle, in actual work, the thin extraction needle can be used as a backup to extract the chicken embryo when the thick extraction needle is blocked. Secondly, since the thin extraction needle can accurately reach the parts of the chicken embryo that are difficult to aspirate, it is possible to aspirate the parts that are difficult to aspirate. The thin extraction needle effectively solves the technical problem of overflow and contamination of the chicken embryo tissue fluid caused by pulling out the blocked needle during work.

[0027] 2. During the working process, when the crude extraction needle is blocked, open the third valve and close the remaining valves. According to the existing conventional method and the existing air blockage removal method, connect the compressed air pipe to the air pump, and pump in compressed air to remove the blockage in the crude extraction needle.

[0028] 3. During the working process, if it is necessary to clean the crude extraction needle, open the second valve, the first valve and close the other valves, and pump sterile compressed air into the cleaning container (there is sterile saline in the cleaning container). At this time, the air pressure in the cleaning container increases, close the second valve, and open the third valve. At this time, due to the strong pressure in the cleaning container, cleaning water is pumped into the crude extraction needle to clean the crude extraction needle. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying creative work.

[0030] Figure 1 It is a schematic diagram of the overall structure in an embodiment of the utility model;

[0031] Figure 2 This is a schematic diagram of the structure of a thin extraction needle and a long hose connected to a coarse extraction needle tube in an embodiment of the utility model;

[0032] Figure 3 It is a schematic diagram of the dispersed structure in the embodiment of the utility model;

[0033] Figure 4 This is a schematic diagram of the dispersed structure of the connecting piece in the embodiment of the utility model;

[0034] Figure 5 This is a schematic diagram of the structure in which the extraction tube is connected to the cleaning container in the embodiment of the utility model.

[0035] The realization of the purpose, functional features and advantages of the utility model will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION

[0036] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0037] It should be noted that all directional indications in the embodiments of the present invention (such as up, down, left, right, front, back...) are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0038] In addition, in the present utility model, descriptions such as "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In addition, the technical solutions between the various embodiments can be combined with each other, but they must be based on the ability of ordinary technicians in the field to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present utility model.

[0039] Example 1

[0040] like Figure 1-5 As shown, a chicken embryo antigen extraction device comprises an extraction needle mechanism, wherein the extraction needle mechanism comprises a coarse extraction needle tube 12, and a thin extraction needle tube assembly 2 is connected on the side wall of the coarse extraction needle tube 12. Specifically, during operation, the coarse extraction needle tube 12 is inserted into the chicken embryo to extract the chicken embryo antigen, and when the coarse extraction needle tube 12 is blocked, in order to avoid pulling out the coarse extraction needle tube 12, which easily causes the chicken embryo tissue fluid to overflow and cause pollution, the thin extraction needle tube assembly 2 comprises a long hose 21 that is connected to the coarse extraction needle tube 12, and the long hose 21 is connected to the thin extraction needle 22 (specifically, according to the existing conventional needle tube connection additional tube mode, a connector 211 is connected to the coarse extraction needle tube 12, and the connector 211 is substantially a connecting nozzle tube. After the long hose 21 is inserted into the connector, it is connected to the coarse extraction needle tube 12). During operation, when the coarse extraction needle tube 12 is blocked, the fine extraction needle 22 is inserted into the chicken embryo. At this time, the coarse extraction needle tube 12 is kept without being pulled out to continue to aspirate the chicken embryo antigen.

[0041] The purpose of designing the thin extraction needle to have a needle opening smaller than the needle opening of the thick extraction needle tube 12 is to reduce the defect of continued clogging.

[0042] In the actual working process, when the crude extraction needle tube 12 can work smoothly, at this time, a clamp for clamping the long hose 21 is installed on the long hose 21, and the long hose 21 remains sealed when clamped by the clamp.

[0043] The crude extraction needle tube 12 is connected to the extraction tube 3 through a connector; specifically, the connector includes a connector seat 11 connected to the crude extraction needle tube 12, and a slot body connected to the crude extraction needle tube 12 is provided on the connector seat 11; a liquid inlet hole connected to the crude extraction needle tube 12 is provided at the bottom of the slot body. At the same time, in order to achieve filtering, an adaptive filter screen 111 is provided in the slot body, and the filter screen pad 111 is at the bottom of the slot body, and the filter screen pad 111 plays a major filtering role.

[0044] Correspondingly, the connecting piece also includes a threaded seat connected to the extraction pipe 3, and a through hole connected to the extraction pipe 3 is opened on the threaded seat; the threaded seat 31 is threadedly connected in the groove body (the groove wall of the groove body is provided with an adaptive threaded structure).

[0045] During operation, the threaded seat 31 is threadedly connected to the connecting seat 11 to achieve a detachable connection. At the same time, according to the existing conventional method, the extraction tube 3 (the extraction tube 3 is a silicone tube) is installed on the peristaltic pump, and the extraction tube 3 is continuously pressed by the peristaltic pump to achieve the extraction of chicken embryo antigen.

[0046] In actual operation, the above device can, firstly, use the thin extraction needle 22 as a backup to extract the chicken embryo when the thick extraction needle 12 is blocked. Secondly, the thin extraction needle 22 can accurately reach the chicken embryo part that is difficult to aspirate, so the part that is difficult to aspirate can be aspirated.

[0047] Example 2

[0048] like Figure 1-5 As shown, in this embodiment, based on the structure of embodiment 1, the extraction tube 3 is connected with a compressed air tube 4. During the extraction process, when the coarse extraction needle tube 12 or the fine extraction needle 22 is blocked, the compressed air tube 4 is connected to an air pump (not shown in the figure) according to the existing conventional gas blockage removal method, and the coarse extraction needle tube 12 and the fine extraction needle 22 are unblocked by pumping in compressed air.

[0049] Specifically, the discharge end of the extraction tube 3 is connected to a collector 7 for collecting samples (the collector 7 is a collection glass bottle).

[0050] The extraction pipe 3 is connected with a lower connecting pipe 5, and the lower connecting pipe 5 is connected with a cleaning container 6. The lower connecting pipe 5 is equipped with a first valve 51; the compressed air pipe 4 is equipped with a second valve 41.

[0051] At the same time, the extraction pipe 3 is equipped with a third valve 33 and a fourth valve 32; the third valve 33 controls the liquid inlet of the extraction pipe 3, and the fourth valve 32 controls the liquid inlet of the collector 7 (according to the existing method, the top position of the collector 7 is connected to the exhaust pipe, and the exhaust pipe is used for exhaust).

[0052] During the working process, first, when the crude extraction needle tube 12 is blocked, open the third valve 33 and close the remaining valves. According to the existing conventional method and the existing air blockage removal method, connect the compressed air pipe 4 to the air compressor (the air compressor is a conventional device for providing compressed air disclosed in the prior art), and pump in sterile compressed air (open valve 41) to remove the blockage in the crude extraction needle tube 12.

[0053] At the same time, during the working process, if it is necessary to clean the crude extraction needle tube 12, at this time, open the first valve 51 and close the remaining valves, pump sterile compressed air into the cleaning container 6 (there is sterile saline in the cleaning container 6). At this time, the air pressure in the cleaning container 6 increases, and open the third valve 33. At this time, due to the strong pressure in the cleaning container 6, the cleaning water is pressed into the crude extraction needle tube 12, and the crude extraction needle tube 12 is cleaned.

[0054] Example 3

[0055] like Figure 1-5 As shown, this embodiment is based on the structure of the embodiment 1, and in the working process, in order to further avoid the technical problem of clogging of the crude extraction needle tube 12. The crude extraction needle tube 12 is equipped with a needle filter sleeve 13, and the needle filter sleeve 13 is provided with a plurality of filter holes. The needle filter sleeve 13 is made of 316L stainless steel, and in the working process, it is fixedly sleeved on the needle filter sleeve 13, and the needle filter sleeve 13 can filter impurities in the working process to prevent them from entering the crude extraction needle tube 12.

[0056] Of course, the above description is not a limitation of the present invention, and the present invention is not limited to the above examples. Changes, modifications, additions or substitutions made by technicians in this technical field within the essential scope of the present invention should also fall within the protection scope of the present invention.

Claims

1. A chicken embryo antigen extraction device, characterized in that: It includes an extraction needle mechanism, the extraction needle mechanism includes a coarse extraction needle tube, and the side wall of the coarse extraction needle tube is connected to a fine extraction needle tube assembly; The thin extraction needle tube assembly includes a long hose connected to the thick extraction needle tube, and the long hose is connected to the thin extraction needle; The crude extraction needle tube is connected to the extraction tube via a connector; The extraction tube is connected with a compressed air tube. During the extraction process, when the coarse extraction needle tube or the fine extraction needle is blocked, the compressed air tube is connected to the air pump, and compressed air is pumped in to clear the coarse extraction needle tube and the fine extraction needle. The discharge end of the extraction tube is connected to a collector for collecting samples.

2. The chicken embryo antigen extraction device according to claim 1, characterized in that: The crude extraction needle tube is equipped with a needle filter sleeve, and the needle filter sleeve is provided with a plurality of filter holes.

3. The chicken embryo antigen extraction device according to claim 1, characterized in that: The connecting piece comprises a connecting seat connected to the crude extraction needle tube, and the connecting seat is provided with a groove body connected to the crude extraction needle tube; The bottom of the tank is provided with a liquid inlet hole connected to the coarse extraction needle tube; The connecting piece also includes a threaded seat connected to the extraction pipe, and the threaded seat is provided with a through hole connected to the extraction pipe; The threaded seat is threadedly connected in the groove body.

4. The chicken embryo antigen extraction device according to claim 3, characterized in that: An adapted filter screen is arranged in the tank body.

5. The chicken embryo antigen extraction device according to claim 1, characterized in that: The extraction tube is connected with a lower connecting tube, and the lower connecting tube is connected with a cleaning container.

6. The chicken embryo antigen extraction device according to claim 5, characterized in that: The lower connecting pipe is equipped with a first valve; The compressed air pipe is equipped with a second valve.

7. The chicken embryo antigen extraction device according to claim 6, characterized in that: The extraction pipe is equipped with a third valve and a fourth valve; The third valve controls the liquid inlet into the extraction pipe, and the fourth valve controls the liquid inlet into the collector.

8. The chicken embryo antigen extraction device according to claim 1, characterized in that: The crude extraction needle tube is equipped with a connector, and the long hose is connected to the connector.

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