Calprotectin concentration detection device

By designing the sampling components and swing components of the calprotectin concentration detection device, the problem of difficulty in sampling thin feces is solved, efficient sampling and mixing of excrement in different states is achieved, and detection efficiency and stability are improved.

CN222232119UActive Publication Date: 2024-12-24JILIN GETEIN BIOTECH CO LTD
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Patent Information

Application Number
CN202420761370.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-15
Publication Date
2024-12-24
Estimated Expiration
2034-04-15

AI Technical Summary

Technical Problem

Since excreted feces usually have dry and thin shapes, existing sampling devices are not convenient to sample thin feces, resulting in low detection efficiency of calprotectin concentration.

Method used

A calprotectin concentration detection device is designed, including a sampling assembly and a swing assembly. The sampling assembly is connected by a slide rod and a test tube holder. The selective use of solid sampling rod and liquid sampling tube is facilitated to sample excrement in different states. And the mixing of reagents and samples is achieved through the swinging assembly to increase working efficiency.

Benefits of technology

The device can effectively sample and mix excrement in different states, improve the efficiency of calprotectin concentration detection, prevent test tube dumping and reagent spilling, and simplify sample processing flow.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of calprotectin detection, and particularly discloses a calprotectin concentration detection device which comprises a mounting support, a sampling assembly, a swing assembly and a detection assembly, the sampling assembly is used for sampling excrement in different states and arranged on the mounting support, and the sampling assembly is arranged on the mounting support. The swing assembly simultaneously mixes a plurality of groups of detection reagents and samples, the swing assembly is fixedly connected to the mounting support, excrement in different states can be sampled through the sampling assembly, the plurality of groups of detection reagents and samples are simultaneously mixed through the swing assembly, and the bottom of the solid sampling rod is processed into an abrasive pattern shape. The liquid sampling tube is made of a soft rubber material, so that the liquid excrement sample can be conveniently pressed and sucked, five test tubes can be stored at the same time through the arrangement of the test tube rack, the test tubes can be prevented from toppling over, reagents in the test tubes are prevented from being scattered, and the five test tubes can be conveniently shaken at the same time.
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Description

Technical Field

[0001] The utility model relates to the technical field of calprotectin detection, in particular to a calprotectin concentration detection device. Background Art

[0002] The content of granulocyte calcium-binding protein in the human body is the basis for detecting acute inflammatory cell activation, and can also be used as the basis for detecting cell-specific or tissue-specific tests. Calprotectin can play a role in transmitting cell signals, as well as antimicrobial effects and immune regulation.

[0003] Among them, calprotectin is a protein containing calcium, which is widely distributed in various parts of the human body. Its content index varies with different parts of the human body. When testing the concentration of calprotectin, a sampling piece is needed to extract samples from the excrement. After the sample and the reagent in the test tube are mixed and allowed to stand, the reagent containing the sample is dropped on the test paper, and the concentration of calprotectin is determined by observing the color change of the test paper. Since the excreted feces usually appear in two states, dry and thin, the rod-shaped sampling piece is not convenient for sampling thin feces. For this reason, we propose a calprotectin concentration detection device. Utility Model Content

[0004] The utility model aims to provide a calprotectin concentration detection device to solve the problem in the above background technology that the excreted feces are usually in two states, dry and thin, and the rod-shaped sampling piece is not convenient for sampling thin feces.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a calprotectin concentration detection device, comprising a mounting support, a sampling assembly, the sampling assembly is used to sample excrement in different states, the sampling assembly is arranged on the mounting support, and a swing assembly, the swing assembly mixes multiple groups of detection reagents and samples at the same time, and the swing assembly is fixedly connected to the mounting support;

[0006] The sampling assembly includes a sliding rod, which is sleeved and connected to a mounting support. A test tube rack is fixedly connected to the sliding rod, a test tube is sleeved in the test tube rack, a connector is threadedly connected to the test tube, a solid sampling rod is installed at one end of the connector, and a liquid sampling tube is installed at the other end of the connector.

[0007] Preferably, a storage plate is provided in the mounting support.

[0008] Preferably, a test paper slot is provided in the storage plate.

[0009] Preferably, a strip plate is fixedly connected to the storage plate, and the strip plate is sleeve-connected to the mounting support.

[0010] Preferably, the swing assembly includes a support frame, the support frame is fixedly connected to the mounting support, the support frame is provided with a rack, a limiting ring is sleeved on the rack, the limiting ring and the support frame are fixedly connected, the rack is meshed with a gear, the gear is fixedly connected with a slot plate, the slot plate is rotatably connected with a pin shaft, and the pin shaft is fixedly connected to the support frame.

[0011] Preferably, a cross bar is rotatably connected in the support frame, a disc is fixedly connected to the cross bar, a cylindrical pin is fixedly connected to the disc, and the cylindrical pin is connected to the slot plate in a sleeve manner.

[0012] Preferably, a hand wheel is fixedly connected to the cross bar.

[0013] Preferably, a reinforcing rib is fixedly connected to the mounting support.

[0014] The utility model has at least the following beneficial effects:

[0015] The utility model can sample excrement in different states through the sampling component, and mix multiple groups of detection reagents and samples at the same time through the swing component. In the sampling component, a thread is arranged on the outer wall of the connector to facilitate connection with the test tube, and round holes are processed at both ends of the connector to facilitate connection with the solid sampling rod and the liquid sampling tube. The selective use of the solid sampling rod and the liquid sampling tube is convenient for sampling excrement in different states. The bottom of the solid sampling rod is processed into a grinding pattern to facilitate attachment of fecal samples. The liquid sampling tube is made of soft rubber material, which is convenient for pressing and absorbing liquid fecal samples. The setting of the test tube rack can store five test tubes at the same time, which can prevent the test tubes from tipping over and the reagents in the test tubes from spilling, and is convenient for the five test tubes to shake at the same time. The rack and the test tube rack are connected together by a sliding rod to ensure that the rack and the test tube rack move synchronously, and multiple test tubes are installed in the test tube rack, so that the multiple test tubes can be shaken at the same time to complete the mixing of reagents and samples, thereby increasing work efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the overall structure of the utility model.

[0017] Figure 2 It is a structural schematic diagram of the sliding rod, the test tube rack and the test tube in the utility model.

[0018] Figure 3 It is an exploded schematic diagram of the connector, the solid sampling rod and the liquid sampling tube in the utility model.

[0019] Figure 4 It is a structural schematic diagram of the disc, cylindrical pin and slot plate in the utility model.

[0020] Figure 5It is a schematic diagram of the structure of the rack, gear and slot plate in the utility model.

[0021] Figure 6 It is a schematic diagram of the structure of the support frame, cross bar and disc in the utility model.

[0022] In the figure: 1-sampling assembly; 2-swing assembly; 3-mounting support; 4-slide rod; 5-test tube rack; 6-test tube; 7-connector; 8-solid sampling rod; 9-liquid sampling tube; 10-storage plate; 11-test paper slot; 12-strip plate; 13-support frame; 14-rack; 15-limiting ring; 16-gear; 17-slot plate; 18-pin shaft; 19-cylindrical pin; 20-disc; 21-cross bar; 22-handwheel; 23-reinforcement rib. DETAILED DESCRIPTION

[0023] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and understandable, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0024] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0025] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure or characteristic that may be included in at least one implementation of the present invention. The term "in one embodiment" that appears in different places in this specification does not necessarily refer to the same embodiment, nor does it refer to a separate or selective embodiment that is mutually exclusive with other embodiments.

[0026] Calprotectin is a protein containing calcium, which is widely distributed in various parts of the human body. Its content index varies with different parts of the human body. When testing the concentration of calprotectin, a sampling piece is needed to extract samples from the excrement. After the sample and the reagent in the test tube are mixed and allowed to stand, the reagent containing the sample is dropped on the test paper. The concentration of calprotectin is determined by observing the color change of the test paper. Since the excreted feces usually appear in two states, dry and thin, the rod-shaped sampling piece is not convenient for sampling thin feces. For this reason, we propose a calprotectin concentration detection device.

[0027] See also Figure 1-Figure 6The utility model provides a technical solution of a calprotectin concentration detection device: a calprotectin concentration detection device, including a mounting support 3, a sampling component 1, the sampling component 1 is used to sample excrement in different states, the sampling component 1 is arranged on the mounting support 3, and a swing component 2, the swing component 2 mixes multiple groups of detection reagents and samples at the same time, and the swing component 2 is fixedly connected to the mounting support 3.

[0028] The calprotectin concentration detection device of this embodiment can sample excreta in different states through the sampling component 1, and simultaneously mix multiple groups of detection reagents and samples through the swing component 2. In the sampling component 1, a thread is provided on the outer wall of the connector 7 to facilitate connection with the test tube 6, and both ends of the connector 7 are processed with round holes to facilitate connection with the solid sampling rod 8 and the liquid sampling tube 9. The selective use of the solid sampling rod 8 and the liquid sampling tube 9 facilitates sampling of excreta in different states. The bottom of the solid sampling rod 8 is processed into a grinding pattern to facilitate The dry stool sample is attached, and the liquid sampling tube 9 is made of soft rubber material, which is convenient for pressing and absorbing the thin stool sample. The setting of the test tube rack 5 can store five test tubes 6 at the same time, which can prevent the test tube 6 from tipping over and avoid the reagent in the test tube 6 from spilling, and it is convenient for the five test tubes 6 to shake at the same time. The rack 14 and the test tube rack 5 are connected together by the sliding rod 4 to ensure that the rack 14 and the test tube rack 5 move synchronously, and multiple test tubes 6 are installed in the test tube rack 5, so that multiple test tubes 6 can be shaken at the same time to complete the mixing of reagents and samples, thereby increasing work efficiency.

[0029] In some embodiments, the sampling assembly 1 includes a sliding rod 4, which is sleeved with a mounting support 3, a test tube rack 5 is fixedly connected to the sliding rod 4, a test tube 6 is sleeved in the test tube rack 5, a connector 7 is threadedly connected to the test tube 6, a solid sampling rod 8 is installed at one end of the connector 7, and a liquid sampling tube 9 is installed at the other end of the connector 7. When sampling solid feces, the solid sampling rod 8 is inserted into the circular hole of the connector 7. Under the action of friction, the solid sampling rod 8 and the connector 7 are connected together, and then the solid sampling rod 8 is inserted into different positions of the feces, part of the feces adheres to the solid sampling rod 8, and then the solid sampling rod 8 is inserted into the test tube 6 to mix with the solvent pre-stored in the test tube 6, and finally the connector is rotated. The connector 7 is threadedly connected to the test tube 6. When sampling thin feces, the liquid sampling tube 9 is inserted into the circular hole of the connector 7. The thin feces is sucked into the liquid sampling tube 9 by squeezing the liquid sampling tube 9. The thin feces sample is introduced into the test tube 6 to mix with the reagent. In this embodiment, a thread is provided on the outer wall of the connector 7 to facilitate connection with the test tube 6, and circular holes are processed at both ends of the connector 7 to facilitate connection with the solid sampling rod 8 and the liquid sampling tube 9. The selective use of the solid sampling rod 8 and the liquid sampling tube 9 facilitates sampling of excrement in different states. The setting of the test tube rack 5 can store five test tubes 6 at the same time to prevent the test tubes 6 from tipping over and avoid spilling of the reagents in the test tubes 6.

[0030] In some embodiments, a storage plate 10 is provided in the mounting support 3, and a test paper slot 11 is opened in the storage plate 10. Five test paper slots 11 are processed in the storage plate 10. The test paper slots 11 are used to store test papers. After the sample and the reagent are mixed, they are dropped on the test paper for detection. The content of calprotectin is determined by the color change of the test paper.

[0031] In some embodiments, a strip plate 12 is fixedly connected to the storage board 10, and the strip plate 12 is sleeved and connected to the mounting support 3. The storage board 10 is installed in the mounting support 3 through the strip plate 12. The setting of the strip plate 12 limits the moving direction of the storage board 10 to ensure the stability of the storage board 10 when in use.

[0032] In some embodiments, the swing assembly 2 includes a support frame 13, the support frame 13 is fixedly connected to the mounting support 3, a rack 14 is provided on the support frame 13, a limit ring 15 is sleeved on the rack 14, the limit ring 15 is fixedly connected to the support frame 13, a gear 16 is meshedly connected to the rack 14, a slot plate 17 is fixedly connected to the gear 16, a pin 18 is rotatably connected in the slot plate 17, and the pin 18 is fixedly connected to the support frame 13. According to the above embodiment, when it is necessary to mix the sample and reagent in the test tube 6, the slot plate 17 is rotated on the outer wall of the pin 18, and the slot plate 17 is provided with a pin 18. The movable gear 16 moves, the gear 16 and the rack 14 mesh, and then the gear 16 drives the rack 14 to reciprocate laterally in the limiting ring 15, and the rack 14 and the test tube rack 5 are connected by the sliding rod 4, and the test tube rack 5 moves with the rack 14, and then the test tube 6 shakes to complete the mixing of the sample and the reagent, and the rack 14 and the test tube rack 5 are connected together by the sliding rod 4 to ensure that the rack 14 and the test tube rack 5 move synchronously, and a plurality of test tubes 6 are installed in the test tube rack 5, and then the plurality of test tubes 6 can be shaken at the same time to complete the mixing of the reagent and the sample, so as to increase the work efficiency.

[0033] In some embodiments, a cross bar 21 is rotatably connected to the support frame 13, a disc 20 is fixedly connected to the cross bar 21, a cylindrical pin 19 is fixedly connected to the disc 20, the cylindrical pin 19 and the slot plate 17 are sleeved and connected, the cross bar 21 rotates in the support frame 13 through a bearing, the disc 20 moves with the cross bar 21, when the disc 20 moves, the cylindrical pin 19 pushes the slot plate 17 to swing, and the rotation of the cross bar 21 can drive the slot plate 17 to swing back and forth.

[0034] In some embodiments, a hand wheel 22 is fixedly connected to the cross bar 21 , and the hand wheel 22 is provided to facilitate the rotation of the cross bar 21 .

[0035] In some embodiments, a reinforcing rib 23 is fixedly connected to the mounting support 3 , and the provision of the reinforcing rib 23 increases the bottom strength of the mounting support 3 .

[0036] Importantly, it should be noted that the construction and arrangement of the present application shown in a plurality of different exemplary embodiments are only exemplary. Although only a few embodiments are described in detail in this disclosure, it should be readily understood by those who refer to this disclosure that many modifications are possible (e.g., the size, scale, structure, shape and ratio of various elements, and parameter values ​​(e.g., temperature, pressure, etc.), installation arrangements, use of materials, color, directional changes, etc.) without substantially departing from the novel teachings and advantages of the subject matter described in the application. For example, the element shown as integrally formed can be composed of multiple parts or elements, the position of the element can be inverted or otherwise changed, and the nature or number or position of the discrete element can be changed or changed. Therefore, all such modifications are intended to be included in the scope of the present utility model. The order or sequence of any process or method steps can be changed or reordered according to alternative embodiments. In the claims, any "device plus function" clause is intended to cover the structure of performing the function described herein, and is not only structurally equivalent but also equivalent structure. Without departing from the scope of the present invention, other substitutions, modifications, changes and omissions may be made in the design, operating conditions and arrangement of the exemplary embodiments. Therefore, the present invention is not limited to a specific embodiment, but extends to various modifications that still fall within the scope of the appended claims.

[0037] Additionally, in order to provide a concise description of example embodiments, all features of an actual embodiment (ie, those features that are not relevant to the best mode presently contemplated for carrying out the invention or those that are not relevant to implementing the invention) may not be described.

[0038] It will be appreciated that in the development of any actual implementation, as in any engineering or design project, numerous implementation-specific decisions may be made. Such a development effort may be complex and time-consuming, but will be a routine task of design, fabrication, and production for those of ordinary skill having the benefit of this disclosure without undue experimentation.

[0039] It should be noted that the above embodiments are only used to illustrate the technical solution of the utility model rather than to limit it. Although the utility model has been described in detail with reference to the preferred embodiments, ordinary technicians in the field should understand that the technical solution of the utility model can be modified or replaced by equivalents without departing from the spirit and scope of the technical solution of the utility model, which should be included in the scope of the claims of the utility model.

Claims

1. A calprotectin concentration detection device, comprising a mounting support (3), characterized in that: A sampling assembly (1), the sampling assembly (1) is used to sample excrement in different states, and the sampling assembly (1) is arranged on a mounting support (3); A swinging assembly (2), wherein the swinging assembly (2) mixes multiple groups of detection reagents and samples simultaneously, and the swinging assembly (2) is fixedly connected to a mounting support (3); The sampling assembly (1) comprises a sliding rod (4), the sliding rod (4) and the mounting support (3) are sleeved and connected, the sliding rod (4) is fixedly connected to a test tube rack (5), a test tube (6) is sleeved in the test tube rack (5), a connector (7) is threadedly connected to the test tube (6), a solid sampling rod (8) is installed at one end of the connector (7), and a liquid sampling tube (9) is installed at the other end of the connector (7).

2. A calprotectin concentration detection device according to claim 1, characterized in that: A storage plate (10) is provided in the mounting support (3).

3. A calprotectin concentration detection device according to claim 2, characterized in that: The storage plate (10) is provided with a test paper slot (11).

4. A calprotectin concentration detection device according to claim 2, characterized in that: A strip plate (12) is fixedly connected to the storage plate (10), and the strip plate (12) and the mounting support (3) are sleeve-connected.

5. A calprotectin concentration detection device according to claim 1, characterized in that: The swing assembly (2) comprises a support frame (13), the support frame (13) and the mounting support (3) are fixedly connected, a rack (14) is provided on the support frame (13), a limit ring (15) is sleeved on the rack (14), the limit ring (15) and the support frame (13) are fixedly connected, a gear (16) is meshedly connected on the rack (14), a slot plate (17) is fixedly connected on the gear (16), a pin shaft (18) is rotatably connected in the slot plate (17), and the pin shaft (18) and the support frame (13) are fixedly connected.

6. A calprotectin concentration detection device according to claim 5, characterized in that: A crossbar (21) is rotatably connected to the support frame (13), a disc (20) is fixedly connected to the crossbar (21), a cylindrical pin (19) is fixedly connected to the disc (20), and the cylindrical pin (19) and the groove plate (17) are sleeved and connected.

7. A calprotectin concentration detection device according to claim 6, characterized in that: A hand wheel (22) is fixedly connected to the cross bar (21).

8. A calprotectin concentration detection device according to claim 1, characterized in that: A reinforcing rib (23) is fixedly connected to the mounting support (3).