Filter for placenta stem cell separation

Abstract

The utility model discloses a filter for placenta stem cell separation, which relates to the technical field of stem cell separation, and comprises a bottom box, the bottom end of the inner cavity of the bottom box is fixedly connected with a collecting vessel, the top end of the bottom box is fixedly connected with a fixed box, the inner cavity of the fixed box is fixedly connected with a collecting hopper, the collecting hopper is funnel-shaped, and the collecting vessel is fixedly connected with the fixed box. The top of the fixing box is fixedly connected with a driving mechanism, and the top of the fixing box is in threaded connection with a dismounting mechanism. According to the filter for placenta stem cell separation, the first teeth at the bottom of the inner cavity of the positioning ring are meshed with the second teeth at the bottom of the outer wall of the rotating frame, so that when the positioning ring rotates, the rotating frame is driven to rotate synchronously, and a second positioning block at the bottom of the rotating frame slides on the inner wall of the positioning ring; and meanwhile, the rotating frame drives the positioning block I to slide on the inner wall of the cover plate, and the positioning block I and the positioning block II are used for guiding the rotating frame, so that the rotating frame does not deviate when rotating, and the rotating frame is more stable when rotating.

Description

Technical Field

[0001] The utility model relates to the technical field of stem cell separation, in particular to a filter used for placental stem cell separation. Background Art

[0002] Placental stem cells are stem cells obtained through placental tissue collection. When a newborn is born, stem cells can generally be obtained through three channels. The first is to collect hematopoietic stem cells from the blood source in the umbilical cord, the second is to collect umbilical cord-derived mesenchymal stem cells from the umbilical cord itself, and the third is to collect placental stem cells from the placenta. The placental tissue is processed by certain experimental methods in the early stage and passed through a filtering device to obtain a large number of various types of stem cells for research and application. A filtering device is required for filtering when extracting placental stem cells.

[0003] For example, a Chinese patent with publication number CN218687099U discloses a filter for separating placental stem cells, including a filter tank, an inlet opened at the center of the top surface of the filter tank, a collecting bucket fixed to the middle of the inner side of the filter tank, and also includes: a transmission cage, the transmission cage is rotatably connected to the upper side of the inner wall of the filter tank, and the transmission cage is rotatably engaged with the inner wall of the filter tank; a filtering rotary screen, the filtering rotary screen is located on the inner side of the transmission cage, and the outer wall of the filtering rotary screen is transmission-connected to the inner wall of the transmission cage; a driving motor, the driving motor is fixed to one side of the outer wall of the filter tank, and the driving motor is transmission-connected to the transmission cage; the utility model can make the filtering rotary screen rotate in a circle through the transmission cage when filtering the placenta, so that the placenta is in a moving state during the filtering process, thereby avoiding congestion of the filter net, and improving the efficiency of stem cell filtration through the movement of the placenta.

[0004] The existing technology has the following problems:

[0005] In the prior art, it is difficult to remove the screening filter for cleaning after filtering the placenta for stem cell separation, which reduces the practicality of the device. At the same time, in the prior art, the screening filter is not limited when separating stem cells from the placenta, resulting in poor stability when the screening filter is rotated again. Utility Model Content

[0006] The utility model provides a filter for separating placental stem cells to solve the problems raised in the above background technology.

[0007] In order to solve the above technical problems, the technical solution adopted by the utility model is:

[0008] A filter for separating placental stem cells comprises a bottom box, the bottom end of the inner cavity of the bottom box is fixedly connected to a collecting vessel, the top of the bottom box is fixedly connected to a fixed box, the inner cavity of the fixed box is fixedly connected to a collecting bucket, the collecting bucket is funnel-shaped, the top of the fixed box is fixedly connected to a driving mechanism, the top of the fixed box is threadedly connected to a disassembly mechanism, the bottom of the disassembly mechanism is slidably connected to a separation mechanism, the driving mechanism comprises a fixed box, the outer wall of the fixed box is fixedly connected to the top of the fixed box, the disassembly mechanism comprises a cover plate, the inner wall of the cover plate is threadedly connected to the top of the fixed box, and the separation mechanism comprises four positioning blocks, the outer wall of the positioning block is slidably connected to the inner wall of the cover plate.

[0009] Preferably, a motor is fixedly connected to the top of the fixing box, an output end of the motor passes through the outer wall of the fixing box and is fixedly connected to a driving gear, and a driven gear is meshed with the outer wall of the driving gear.

[0010] Preferably, four limit blocks 1 are fixedly connected to the top of the driven gear in a circular array, the outer wall of the limit block 1 is slidably connected to the top of the fixed box, and the shape of the limit block 1 is T-shaped.

[0011] Preferably, a positioning ring is fixedly connected to the inner wall of the driven gear, and a tooth 1 is fixedly connected to the bottom of the inner cavity of the positioning ring in a circular array.

[0012] Preferably, a feed port is fixedly connected to the top of the cover plate, four fixing rods are fixedly connected to the bottom of the inner cavity of the feed port in a circular array, and one end of the fixing rod is fixedly connected to a connecting rod.

[0013] Preferably, the bottom end of the connecting rod is rotatably connected to a filter screen, and the outer wall of the filter screen is fixedly connected to four limit blocks 2 in a circular array.

[0014] Preferably: the bottom end of the positioning block one is fixedly connected to a rotating frame, the bottom of the outer wall of the rotating frame is fixedly connected to tooth two in a circular array, the outer wall of tooth two is meshed with the outer wall of tooth one, the bottom of the inner cavity of the rotating frame is slidably connected to the outer wall of the filter, and the inner wall of the rotating frame is slidably connected to the outer wall of limit block two.

[0015] Preferably, a second positioning block is fixedly connected to the bottom end of the rotating frame, and an outer wall of the second positioning block is slidably connected to the bottom of the positioning ring.

[0016] Due to the adoption of the above technical solution, the utility model has achieved the following technical progress compared with the prior art:

[0017] 1. The utility model provides a filter for separating placental stem cells. By twisting the cover plate, the inner wall of the cover plate is no longer threadedly connected to the outer wall of the top of the fixed box, and then the cover plate can be taken down, so that the inner wall of the cover plate is no longer in contact with the outer wall of the positioning block 1. At the same time, the cover plate drives the fixing rod and the connecting rod to move upward synchronously, so that the connecting rod drives the filter to move synchronously, so that the limit block 2 fixedly connected to the outer wall of the filter slides on the inner wall of the rotating frame. When the outer wall of the limit block 2 is no longer in contact with the inner wall of the rotating frame, the filter has been completely taken out at this time, and then the filter can be cleaned. At the same time, the rotating frame can be pulled upward, so that the outer wall of the positioning block 2 is no longer in contact with the inner wall of the positioning ring, so that the rotating frame can be taken out and cleaned, which has the effect of facilitating disassembly and cleaning.

[0018] 2. The utility model provides a filter for separating placental stem cells. By starting the motor, the driving gear is meshed with the driven gear, and the driven gear drives the limiting block 1 to slide synchronously on the inner wall of the fixed box. The limiting block guides the driven gear to limit the driven gear, so that the driven gear rotates more smoothly without deviation or falling off. At the same time, the driven gear drives the positioning ring to rotate synchronously. Since the teeth 1 at the bottom of the inner cavity of the positioning ring and the teeth 2 at the bottom of the outer wall of the rotating frame are meshed with each other, when the positioning ring rotates, the rotating frame is driven to rotate synchronously, so that the positioning block 2 at the bottom of the rotating frame slides on the inner wall of the positioning ring. At the same time, the rotating frame drives the positioning block 1 to slide on the inner wall of the cover plate. The positioning blocks 1 and 2 guide the rotating frame, so that the rotating frame will not deviate when it rotates, and the rotating frame can rotate more stably. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a structural schematic diagram of the main view of the utility model;

[0020] Figure 2 It is a schematic diagram of the cutaway structure of the main view of the utility model;

[0021] Figure 3 It is a structural schematic diagram of the driving mechanism of the utility model;

[0022] Figure 4 For this utility model Figure 2 The enlarged structural diagram at A in the middle;

[0023] Figure 5 For this utility model Figure 3 Enlarged structural diagram at B in the middle.

[0024] In the figure: 1. bottom box; 11. collecting container; 12. fixed box; 13. collecting bucket; 2. driving mechanism; 21. fixed box; 22. motor; 23. driving gear; 24. driven gear; 25. limit block 1; 26. positioning ring; 3. disassembly mechanism; 31. cover plate; 32. feed port; 33. fixing rod; 34. connecting rod; 35. filter screen; 36. limit block 2; 4. separation mechanism; 41. rotating frame; 42. positioning block 1; 43. positioning block 2. DETAILED DESCRIPTION

[0025] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

[0026] like Figure 1-Figure 3 As shown, a filter for separating placental stem cells comprises a bottom box 1, the bottom end of the inner cavity of the bottom box 1 is fixedly connected with a collecting vessel 11, the top of the bottom box 1 is fixedly connected with a fixed box 12, the inner cavity of the fixed box 12 is fixedly connected with a collecting bucket 13, the collecting bucket 13 is funnel-shaped, the top of the fixed box 12 is fixedly connected with a driving mechanism 2, the top of the fixed box 12 is threadedly connected with a disassembly mechanism 3, the bottom of the disassembly mechanism 3 is slidably connected with a separation mechanism 4, the driving mechanism 2 comprises a fixed box 21, the outer wall of the fixed box 21 is fixedly connected to the top of the fixed box 12, the disassembly mechanism 3 comprises a cover plate 31, the inner wall of the cover plate 31 is threadedly connected to the top of the fixed box 12, and the separation mechanism 4 comprises four positioning blocks 42, the outer wall of the positioning block 42 is slidably connected to the inner wall of the cover plate 31.

[0027] The separation mechanism 4 is rotated by the driving mechanism 2 to separate stem cells from the placenta in the separation mechanism 4 , and the device is subsequently quickly disassembled by the disassembly mechanism 3 to facilitate cleaning of the separation mechanism 4 .

[0028] like Figure 2 , Figure 3 As shown, a motor 22 is fixedly connected to the top of the fixed box 21, and an output end of the motor 22 passes through the outer wall of the fixed box 21 and is fixedly connected to a driving gear 23. A driven gear 24 is meshed with the outer wall of the driving gear 23, and four limit blocks 25 are fixedly connected to the top of the driven gear 24 in a circular array. The outer wall of the limit block 25 is slidably connected to the top of the fixed box 12, and the shape of the limit block 25 is T-shaped.

[0029] By starting the motor 22, the driving gear 23 is driven to rotate, so that the driving gear 23 is meshed with the driven gear 24, and the driven gear 24 is driven to rotate synchronously. The driven gear 24 drives the limit block 25 to slide synchronously on the inner wall of the fixed box 12. The limit block 25 limits and guides the driven gear 24, so that the driven gear 24 rotates more smoothly without deviation or falling off.

[0030] like Figure 2 , Figure 3 As shown, a positioning ring 26 is fixedly connected to the inner wall of the driven gear 24, and a tooth 1 is fixedly connected to the bottom of the inner cavity of the positioning ring 26 in a circular array.

[0031] When the driven gear 24 rotates, it drives the positioning ring 26 to rotate synchronously. Since the tooth 1 at the bottom of the inner cavity of the positioning ring 26 is meshed with the tooth 2 at the bottom of the outer wall of the rotating frame 41, when the positioning ring 26 rotates, it drives the rotating frame 41 to rotate synchronously, thereby separating the placenta stem cells in the rotating frame 41.

[0032] like Figure 2 , Figure 3 As shown, a feed port 32 is fixedly connected to the top of the cover plate 31 , and four fixing rods 33 are fixedly connected to the bottom of the inner cavity of the feed port 32 in a circular array, and one end of the fixing rod 33 is fixedly connected to a connecting rod 34 .

[0033] By screwing the cover plate 31, the inner wall of the cover plate 31 is no longer threadedly connected to the outer wall of the top of the fixing box 12, and then the cover plate 31 can be taken down, and at the same time, the cover plate 31 drives the fixing rod 33 and the connecting rod 34 to move upward synchronously.

[0034] like Figure 2 , Figure 3 As shown, the bottom end of the connecting rod 34 is rotatably connected to a filter screen 35, and the outer wall of the filter screen 35 is fixedly connected to four limit blocks 36 in a circular array.

[0035] When the connecting rod 34 moves upward, the filter 35 is driven to move synchronously, so that the second limit block 36 fixedly connected to the outer wall of the filter 35 slides on the inner wall of the rotating frame 41. When the outer wall of the second limit block 36 is no longer in contact with the inner wall of the rotating frame 41, the filter 35 can be taken out and cleaned.

[0036] like Figure 2-Figure 5 As shown, the bottom end of the positioning block 1 42 is fixedly connected to the rotating frame 41, the bottom of the outer wall of the rotating frame 41 is fixedly connected to the tooth 2 in a circular array, the outer wall of the tooth 2 is meshed with the outer wall of the tooth 1, the bottom of the inner cavity of the rotating frame 41 is slidably connected to the outer wall of the filter 35, the inner wall of the rotating frame 41 is slidably connected to the outer wall of the limit block 2 36, the bottom end of the rotating frame 41 is fixedly connected to the positioning block 23, and the outer wall of the positioning block 23 is slidably connected to the bottom of the positioning ring 26.

[0037] When the rotating frame 41 rotates, the positioning block 2 43 at the bottom of the rotating frame 41 slides on the inner wall of the positioning ring 26, and the rotating frame 41 drives the positioning block 1 42 to slide on the inner wall of the cover plate 31. The positioning block 1 42 and the positioning block 2 43 guide the rotating frame 41, so that the rotating frame 41 will not deviate when rotating, and the rotating frame 41 is more stable when rotating. When the rotating frame 41 rotates, the filter screen 35 is driven to rotate synchronously, thereby driving the placenta in the rotating frame 41 to rotate synchronously, so that stem cells at various positions of the placenta can be separated, and the separated stem cells are filtered by the filter screen 35. After the stem cells are filtered, they fall into the collecting bucket 13, and the collecting bucket 13 sends the stem cells to the collecting vessel 11, thereby completing the separation of the stem cells and achieving the effect of separating and filtering the stem cells.

[0038] The working principle of the utility model is as follows: when in use, the placenta to be separated from the stem cells is placed into the rotating frame 41 through the feed port 32, and then the motor 22 is started to drive the driving gear 23 to rotate, so that the driving gear 23 is meshed with the driven gear 24, driving the driven gear 24 to rotate synchronously, and the driven gear 24 drives the limit block 25 to slide synchronously on the inner wall of the fixed box 12, and the limit block 25 is used to limit and guide the driven gear 24, so that the driven gear 24 rotates more smoothly without deviation or falling off, and at the same time, the driven gear 24 drives the positioning ring 26 to rotate synchronously, because the bottom of the inner cavity of the positioning ring 26 The tooth 1 is meshed with the tooth 2 at the bottom of the outer wall of the rotating frame 41, so when the positioning ring 26 rotates, the rotating frame 41 is driven to rotate synchronously, so that the positioning block 2 43 at the bottom of the rotating frame 41 slides on the inner wall of the positioning ring 26, and the rotating frame 41 drives the positioning block 1 42 to slide on the inner wall of the cover plate 31. The positioning block 1 42 and the positioning block 2 43 guide the rotating frame 41, so that the rotating frame 41 will not deviate when rotating, so that the rotating frame 41 is more stable when rotating. When the rotating frame 41 rotates, the filter screen 35 is driven to rotate synchronously, thereby driving the placenta in the rotating frame 41 to rotate synchronously, so that each position of the placenta The stem cells placed in the container 12 can be separated, and the separated stem cells are filtered by the filter 35. After the stem cells are filtered, they fall into the collection bucket 13, and the collection bucket 13 sends the stem cells to the collection vessel 11, thereby completing the separation of the stem cells and achieving the effect of separating and filtering the stem cells. Subsequently, when it is necessary to clean the filter 35 and the rotating frame 41, the cover plate 31 is twisted so that the inner wall of the cover plate 31 is no longer threadedly connected to the outer wall of the top of the fixed box 12, and then the cover plate 31 can be taken down so that the inner wall of the cover plate 31 is no longer in contact with the outer wall of the positioning block 42, and at the same time, the cover plate 31 drives the fixing rod When the filter screen 35 is removed from the rotating frame 41, the outer wall of the limit block 36 is no longer in contact with the inner wall of the rotating frame 41, and the filter screen 35 has been completely removed. The filter screen 35 can then be cleaned. At the same time, the rotating frame 41 can be pulled upward so that the outer wall of the positioning block 23 is no longer in contact with the inner wall of the positioning ring 26. The rotating frame 41 can then be removed and cleaned, which facilitates disassembly and cleaning, thereby greatly improving the user experience.

[0039] The above shows and describes the basic principle and main features of the utility model and the advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.

Claims

1. A filter for separating placental stem cells, comprising a bottom box (1), characterized in that: The bottom end of the inner cavity of the bottom box (1) is fixedly connected to a collecting container (11), the top end of the bottom box (1) is fixedly connected to a fixed box (12), the inner cavity of the fixed box (12) is fixedly connected to a collecting bucket (13), the collecting bucket (13) is funnel-shaped, the top of the fixed box (12) is fixedly connected to a driving mechanism (2), the top of the fixed box (12) is threadedly connected to a disassembly mechanism (3), the bottom of the disassembly mechanism (3) is slidably connected to a separation mechanism (4), the driving mechanism (2) comprises a fixed box (21), the outer wall of the fixed box (21) is fixedly connected to the top of the fixed box (12), the disassembly mechanism (3) comprises a cover plate (31), the inner wall of the cover plate (31) is threadedly connected to the top of the fixed box (12), and the separation mechanism (4) comprises four positioning blocks (42), the outer wall of the positioning block (42) is slidably connected to the inner wall of the cover plate (31).

2. A filter for separating placental stem cells according to claim 1, characterized in that: The top end of the fixed box (21) is fixedly connected to a motor (22), the output end of the motor (22) passes through the outer wall of the fixed box (21) and is fixedly connected to a driving gear (23), and the outer wall of the driving gear (23) is meshed with a driven gear (24).

3. A filter for separating placental stem cells according to claim 2, characterized in that: The top end of the driven gear (24) is fixedly connected to four limit blocks (25) in a circular array, the outer wall of the limit block (25) is slidably connected to the top of the fixed box (12), and the shape of the limit block (25) is T-shaped.

4. A filter for separating placental stem cells according to claim 2, characterized in that: A positioning ring (26) is fixedly connected to the inner wall of the driven gear (24), and a toothed tooth is fixedly connected to the bottom of the inner cavity of the positioning ring (26) in a circular array.

5. A filter for separating placental stem cells according to claim 1, characterized in that: The top of the cover plate (31) is fixedly connected to a feed port (32), the bottom of the inner cavity of the feed port (32) is fixedly connected to four fixing rods (33) in a circular array, and one end of the fixing rod (33) is fixedly connected to a connecting rod (34).

6. A filter for separating placental stem cells according to claim 5, characterized in that: The bottom end of the connecting rod (34) is rotatably connected to a filter screen (35), and the outer wall of the filter screen (35) is fixedly connected to four limiting blocks (36) in a circular array.

7. A filter for separating placental stem cells according to claim 1, characterized in that: The bottom end of the positioning block 1 (42) is fixedly connected to a rotating frame (41), the bottom of the outer wall of the rotating frame (41) is fixedly connected to teeth 2 in a circular array, the outer wall of the teeth 2 is meshed with the outer wall of the teeth 1, the bottom of the inner cavity of the rotating frame (41) is slidably connected to the outer wall of the filter screen (35), and the inner wall of the rotating frame (41) is slidably connected to the outer wall of the limiting block 2 (36).

8. A filter for separating placental stem cells according to claim 7, characterized in that: A second positioning block (43) is fixedly connected to the bottom end of the rotating frame (41), and an outer wall of the second positioning block (43) is slidably connected to the bottom of the positioning ring (26).

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