Carbon dioxide incubator with bottle rolling device
By designing a bottle roller and layered support frame in a carbon dioxide incubator, the problems of cross infection and carbon dioxide leakage are solved, the stability of the environment in the incubator and the uniformity of cell growth are achieved, and the experimental efficiency is improved.
Patent Information
- Application Number
- CN202323298518.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2023-12-05
- Publication Date
- 2024-12-31
- Estimated Expiration
- 2033-12-05
AI Technical Summary
Existing carbon dioxide incubators are prone to cross infection and carbon dioxide leakage when using bottle rollers, which affects the uniformity of cell culture and environmental stability.
A carbon dioxide incubator with bottle roller was designed to ensure sealing effect by setting a motor outside the box and connecting the rollers with seals, and designing a layered support frame in the box to reduce cross infection. Mix cultures evenly by rotating movement to improve uniformity of cell growth.
It effectively prevents the leakage and cross-infection of carbon dioxide, ensures the stability of the environment in the incubator and the uniformity of cell growth, and improves experimental efficiency and production efficiency.
Smart Images

Figure CN222274578U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of incubators, in particular to a carbon dioxide incubator with a bottle roller. Background Art
[0002] A carbon dioxide incubator is a device used in biological laboratories and biopharmaceutical fields to provide controlled culture conditions to support cell culture, microbial culture and other biological experiments. The carbon dioxide incubator and bottle roller are usually used together to provide controlled culture conditions to support cell culture, microbial culture and other biological experiments. However, most existing constant temperature bottle rollers are placed in a carbon dioxide box for use. During use, most rollers are prone to cross infection in the event of leakage. At the same time, there is also the problem of carbon dioxide leakage in the drive shaft hole. Therefore, in response to the above problems, the present application proposes a carbon dioxide incubator with a bottle roller to solve the problems of cross infection and carbon dioxide leakage. Utility Model Content
[0003] In view of the deficiencies in the prior art, the utility model provides a carbon dioxide incubator with a bottle roller, which solves the problems raised in the above-mentioned background technology.
[0004] In order to achieve the above objectives, the present invention is implemented through the following technical solutions:
[0005] A carbon dioxide incubator with a bottle roller, comprising a box body and a bottle roller arranged in the box body, wherein the bottle roller is composed of a support frame and a roller, and the box body is a carbon dioxide incubator;
[0006] The support frame is multi-layered, and the outer surface of each layer is sealed and connected to the inner wall of the box body;
[0007] The roller member includes a plurality of rollers and a plurality of motors;
[0008] Multiple motors are arranged outside the box body and drive multiple rollers located on the support plate to rotate;
[0009] One side of the box corresponding to the multiple rollers is connected to a seal through a rotating joint. One side of the seal is located inside the box and connected to one end of the roller, and the other side of the seal is located outside the box and connected to the motor drive end through a rotating shaft.
[0010] Through the above technical features, we added a roller bottle design in the carbon dioxide incubator to maintain the uniformity of cell growth. In order to ensure the design of driving the roller bottle, we placed the motor outside the box, which is more helpful for later maintenance. On this basis, we connected the motor and the roller through a seal to increase the sealing effect of the equipment.
[0011] Optionally, a transparent window is provided on the surface of the box body via a rotating shaft, and a sealed box door is provided on the surface of the box body wrapping around the transparent window.
[0012] Through the above technical features, we can open the sealed box door and observe the working conditions inside the box through the transparent window.
[0013] Optionally, a brakeable roller is provided at the bottom of the box.
[0014] Through the above technical solution, the box body is provided with brakeable rollers so that it can be moved freely according to the usage.
[0015] Optionally, the support frame is composed of multiple groups of support plates and multiple support rods, the multiple groups of support plates are distributed up and down in the box, and the surfaces of the multiple groups of support plates are sealed and fitted with the inner wall of the box; the support rods are used to support two adjacent groups of support plates.
[0016] Through the above technical solution, the support frame is spaced and layered to reduce the occurrence of cross infection.
[0017] Optionally, the sealing member is composed of an interface pipe and an aviation joint.
[0018] Through the above technical solution, the sealing effect of the seal is achieved, carbon dioxide is prevented from escaping and the stability of the environment in the box is ensured.
[0019] The utility model provides a carbon dioxide incubator with a bottle roller, which has the following beneficial effects:
[0020] 1. Put the bottle into the CO2 incubator through the bottle roller, pass the bottle roller motor and drive shaft outside the box, and connect them with seals to prevent carbon dioxide from escaping and ensure the stability of the environment in the box, so as to simulate the environment of the cells required for the experiment with the bottle roller.
[0021] 2. The support frame inside the box is designed with independent layers to reduce the possibility of cross infection.
[0022] 3. The design of the roller bottle in the box can evenly mix the liquid or solution in the culture through continuous and gentle rolling motion, ensuring that the cells or microorganisms can evenly contact the culture medium and oxygen. This helps to maintain the uniformity of cell growth and prevent sedimentation and uneven distribution of oxygen.
[0023] 4. The design of roller bottles in the box can improve the efficiency of production and experiments, especially for culture conditions that require periodic mixing and oxygen supply. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] Figure 1 It is a schematic diagram of the structure of the utility model;
[0025] Figure 2This is a schematic diagram of the roller structure of the utility model;
[0026] Figure 3 This is a schematic diagram of the structure of the roller member of the utility model.
[0027] In the figure: 1. box body; 2. bottle roller; 21. support frame; 211. support plate; 212. support rod; 22. roller; 221. roller; 222. motor; 3. transparent window; 4. sealed box door; 5. roller; 6. sealing element; 61. interface pipe; 62. aviation joint; 7. rotary joint; 8. rotating shaft. DETAILED DESCRIPTION
[0028] In order to make the technical means, creative features, objectives and effects of the present invention easier to understand, the present invention is further described below in conjunction with specific embodiments.
[0029] In the description of the present invention, it should be understood that the terms "lateral", "longitudinal", "end", "edge", "sidewall", "up", "down", "upper part", "lower part", "directly above", "surface", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "axial", "radial", "circumferential", "end", "head" and "tail" etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the technical solution of the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.
[0030] The present application proposes a carbon dioxide incubator with a bottle roller, specifically:
[0031] For reference Figure 1 , mainly composed of a box body 1 and a bottle roller 2 arranged in the box body 1, wherein the box body 1 is an existing carbon dioxide incubator; most of the existing carbon dioxide incubators have a placement tray inside to support cell culture. In order to further improve the culture yield, we further adjust the existing placement tray inside the box body 1 and replace it with a bottle roller 2. At the same time, the motor 222 that drives the bottle roller 2 is connected to the outside of the box body 1 through a sealing member 6 to obtain corresponding sealing during the driving process.
[0032] Among them, the bottle roller 2 is mainly composed of a support frame 21 and a roller member 22; the support frame 21 is used to support the roller member 22; and in order to avoid cross infection, we have designed the support frame 21 in layers, and its specific structure is composed of a plurality of support plates 211 and a plurality of support rods 212; the support plates 211 are arranged in the box body 1 with each layer of solid support body; at the same time, the left and right sides of each layer of support plates 211 are pressed against the edge of the inner wall of the box body 1, and the parts closely connected with the box body 1 are sealed again; the support rods 212 are used to separate and support each layer of support plates 211.
[0033] For reference Figure 1-2 As described above, both sides of the support frame 21 fit tightly into the box body 1. To further prevent liquid from flowing downward under explosion, we have also made a heightened design at the front and rear sides of the support frame 21. Therefore, when a bottle carried by the roller member 22 on a certain layer of the support frame 21 breaks, the contact between the downward flow and the lower side of the support frame 21 can be reduced, thereby achieving layered processing and reducing the problem of cross infection.
[0034] For reference Figure 1-2 The roller member 22 mainly supports the cylindrical bottle for rotation. The rolling motion helps to maintain uniform distribution of cells in the culture medium, reducing the risk of cell aggregation and precipitation; and can further improve the consistency and quality of cell growth.
[0035] For reference Figure 1-2 The roller member 22 is mainly composed of multiple rollers 221 and multiple motors 222. However, in order to facilitate later maintenance and other issues, the motor 222 that drives the roller 221 to move is arranged outside the box 1, thereby providing convenience in maintenance and reducing the impact of the internal movement of the box 1 on the motor.
[0036] In one embodiment, we set the roller members 22 equidistantly on the support frame 21 to achieve the use of cell-carrying bottles of different sizes. However, in another embodiment, we can set the roller members 22 on the support frame 21 in an unequal manner to meet the problem of placing and using cell-carrying bottles of different sizes. Based on the different carrying bottles, we can set the spacing between each layer of the support frame 21 to be different to adapt to the placement and use of cell culture fluid carrying bottles of different sizes.
[0037] Also refer to Figure 3 When the motor 222 is arranged outside the box 1, we consider whether the carbon dioxide inside the box 1 will escape and affect the stability of the environment inside the box. We connect the roller 221 and the motor 222 through a set of seals 6.
[0038] For reference Figure 3The seal 6 is arranged on one side of the box 1 corresponding to the roller 221 through a rotary joint, wherein each roller 221 needs to be connected to a motor 222 through a seal 6 for rotation. We do not limit the number of rollers 221. We design it according to actual needs and connect the same number of seals 6 with the same number of motors 222.
[0039] For reference Figure 3 The seal 6 is mainly composed of an interface tube 61 and an aviation joint 62. The interface tube 61 is tightly inserted into the aviation joint 62, and some insertion force or other connection means are required to ensure that the connection is tight and will not fall off accidentally; thereby establishing a connection and ensuring sealing; one side of the seal 6 is connected to the motor 222 through a rotating shaft, and a rotational force is transmitted to the rotating shaft 8 through the motor 222, thereby prompting the seal 6 to rotate, wherein the rotation of the seal 6 needs to be driven by the connected rotary joint 7 to rotate, and the rotary joint 7 is installed on the box body 1 to play a supporting effect, thereby prompting the roller 221 connected to the other side of the seal 6 to rotate.
[0040] Therefore, during the cell cultivation process, we can make the box 1 cooperate with the roller bottle 2 to simulate the environment for achieving the desired cells, which helps to evenly distribute gas and nutrients in the culture medium, thereby promoting the healthy growth of cells.
[0041] In the utility model, the working steps of the device are as follows:
[0042] 1. First, we place the cell culture bottle on the roller 221 and drive it to rotate through the driving motor 222;
[0043] 2. Secondly, since each roller 221 is connected to a motor 222, we can drive only the roller 221 on which the cell culture bottle is placed;
[0044] 3. Then, when the rotation stops, we can open the sealed box door 4 and observe the internal situation of the box body 1 with the transparent window 3 closed. If the cells are not well cultured, we can close the sealed box door 4 and restart the rotation of the roller 221. The transparent window 3 is closed to observe the internal cells, which can reduce the excessive escape of carbon dioxide from the box body 1. When the roller 221 is restarted, the stability of the environment in the box can be quickly restored.
[0045] 4. Finally, the built-in brakeable roller 5 can be moved at will according to the change of the use position.
[0046] The above shows and describes the basic principles, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited to the above embodiments. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of protection claimed by the utility model. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.
Claims
1. A carbon dioxide incubator with a bottle roller, characterized in that: It comprises a box body (1) and a bottle rolling member (2) arranged in the box body (1), wherein the bottle rolling member (2) is composed of a support frame (21) and a roller member (22); The support frame (21) is multi-layered, and the outer surface of each layer is sealed and connected to the inner wall of the box body (1); The roller member (22) includes a plurality of rollers (221) and a plurality of motors (222); The plurality of motors (222) are all arranged outside the box (1) and drive the plurality of rollers (221) located on the support plate (211) to rotate; One side of the box body (1) corresponding to the plurality of rollers (221) is connected to a sealing member (6) via a rotating joint (7); one side of the sealing member (6) is located inside the box body (1) and connected to one end of the roller (221); the other side of the sealing member (6) is located outside the box body (1) and connected to the driving end of the motor (222) via a rotating shaft (8).
2. The carbon dioxide incubator with a bottle roller according to claim 1, characterized in that: The surface of the box body (1) is provided with a transparent window (3) via a rotating shaft, and the surface of the box body (1) is provided with a sealed box door (4) wrapping around the transparent window (3).
3. The carbon dioxide incubator with a bottle roller according to claim 1, characterized in that: The bottom of the box body (1) is provided with a brakeable roller (5).
4. The carbon dioxide incubator with a bottle roller according to claim 1, characterized in that: The support frame (21) is composed of multiple groups of support plates (211) and multiple support rods (212).
5. The carbon dioxide incubator with a bottle roller according to claim 4, characterized in that: The plurality of groups of support plates (211) are vertically distributed in the box body (1), and the surfaces of the plurality of groups of support plates (211) are sealed and fitted with the inner wall of the box body (1); the support rods (212) are used to support two adjacent groups of support plates (211).
6. The carbon dioxide incubator with a bottle roller according to claim 1, characterized in that: The box (1) is a carbon dioxide incubator.
7. The carbon dioxide incubator with a bottle roller according to claim 1, characterized in that: The sealing member (6) is composed of a mouthpiece (61) and an aviation joint (62).
