DNA synthesis column loading device

Abstract

The utility model discloses a DNA (deoxyribonucleic acid) synthesis column loading device, which belongs to the technical field of DNA synthesis and comprises a loading frame component, spring lifting rods are mounted on two sides of the loading frame component, a rectangular plate component is mounted above the two spring lifting rods, and a loading bottom plate is slidably connected to the bottom of the rectangular plate component. An electric lifting rod is arranged above the rectangular plate assembly, a pressing rod assembly is installed on the side, close to the rectangular plate assembly, of the electric lifting rod, and the loading frame assembly is connected with the electric lifting rod through a movable cleaning device; the movable cleaning device is arranged, so that a worker can move the device to a certain degree through brake wheels when needed, and the device can clean structures such as a rectangular plate assembly to a certain degree through cooperation of structures such as a pump body and a spray head when needed; and therefore, the working requirements under different conditions can be better met, and the working capability of the device is further improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of DNA synthesis, and in particular relates to a DNA synthesis column loading device. Background Art

[0002] DNA, which refers to deoxyribonucleic acid, is an organic compound with a complex molecular structure. It exists in the cell nucleus as a component of chromosomes. Its function is to store genetic information. DNA molecules are huge and are composed of nucleotides.

[0003] Chinese patent application No. 202022116113.1 discloses a DNA synthesis column loading device, including a base plate, spring lifting rods are symmetrically provided on both sides of the upper end of the base plate, a synthesis column placement plate is horizontally fixed on the inner side of the spring lifting rods, a loading rectangular plate is horizontally fixed on the top of the spring lifting rods, buffer blocks are symmetrically provided on both sides of the upper end of the loading rectangular plate, a pressure plate is horizontally fixed between the buffer blocks, and a loading cylindrical pressure rod is evenly provided on the bottom surface of the pressure plate corresponding to the loading tube arranged in the loading filling groove area. When the utility model is used, one end of the loading tube is inserted into the loading positioning ring through the downward pressure, and then the loading cylindrical pressure rod arranged on the pressure plate makes the synthesis column filler in the loading tube fall smoothly into the container arranged in the synthesis column loading rack, so as to realize the simultaneous filling of 50 DNA synthesis columns without cross-contamination. The utility model is simple to use, efficient, and will not cause waste of filler.

[0004] 1. The above-mentioned disclosed patent has the problem of being inconvenient to move and to clean structures such as loading rectangular plates, thereby reducing the working capacity of the device; 2. The above-mentioned disclosed patent has the problem of being unable to sterilize structures such as loading rectangular plates when needed, thereby easily causing structures such as loading rectangular plates to be contaminated by bacteria, affecting the normal progress of work, and thus reducing the practicality of the device. Utility Model Content

[0005] In order to solve the problems raised in the above background technology, the utility model provides a DNA synthesis column loading device, which has the characteristics of high working capacity and strong practicality.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a DNA synthesis column loading device, comprising a loading frame assembly, spring lifting rods are installed on both sides of the loading frame assembly, a rectangular plate assembly is installed above the two spring lifting rods, the bottom of the rectangular plate assembly is slidably connected to a loading base plate, an electric lifting rod is arranged above the rectangular plate assembly, a pressure rod assembly is installed on the side of the electric lifting rod close to the rectangular plate assembly, the loading frame assembly and the electric lifting rod are connected by a mobile cleaning device, and a sterilization treatment device is arranged on the outside of the rectangular plate assembly.

[0007] Preferably, the mobile cleaning device includes a fixed frame, brake wheels and a cleaning assembly. The loading frame assembly and the electric lifting rod are connected via the fixed frame. A plurality of brake wheels are installed below the fixed frame. Cleaning assemblies are installed on both sides of the fixed frame near the edges.

[0008] Preferably, the cleaning assembly includes a motor, a screw, a pump body, an L-shaped box and a nozzle. The motor is installed on the inner side of the fixed frame and on both sides of the rectangular plate assembly. The screw is installed on the side of the motor away from the rectangular plate assembly. The L-shaped box is installed on the outer side of the screw through a thread. The nozzle is installed on the top of the L-shaped box near one side of the motor, and the pump body is installed above the L-shaped box.

[0009] Preferably, the cleaning assembly further comprises a partition net, and the partition net is installed on the inner side of the liquid inlet end of the pump body.

[0010] Preferably, the sterilization treatment device includes a support plate, a sterilization lamp and a quartz glass frame. The support plate is installed on the inner side of the fixed frame and on one side of the two spring lifting rods. The quartz glass frame is arranged above the support plate and on the outer side of the rectangular plate assembly. Multiple sterilization lamps are installed in the side wall of the quartz glass frame.

[0011] Preferably, the sterilization treatment device further comprises an electric telescopic rod, and the support plate and the quartz glass frame are connected by the electric telescopic rod.

[0012] Compared with the prior art, the beneficial effects of the utility model are:

[0013] 1. The utility model provides a mobile cleaning device so that the staff can move the position of the device to a certain extent through the various brake wheels when needed, and the device can perform certain cleaning work on structures such as rectangular plate assemblies through the cooperation of structures such as a pump body and a nozzle when needed, so as to better meet the work needs in different situations and thus improve the working capacity of the device.

[0014] 2. The utility model is provided with a sterilization device, so that the device can perform certain sterilization treatment on structures such as rectangular plate assemblies through the cooperation of structures such as sterilization lamps and quartz glass frames when needed, thereby reducing the possibility of rectangular plate assemblies and other structures being contaminated by bacteria, ensuring the normal operation, and further improving the practicality of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a three-dimensional diagram of the utility model;

[0016] Figure 2 It is a three-dimensional cutaway view of the utility model;

[0017] Figure 3 It is a three-dimensional cutaway view of the mobile cleaning device of the utility model;

[0018] Figure 4 It is a three-dimensional cutaway view of the sterilization treatment device of the utility model.

[0019] In the figure: 1. Electric lifting rod; 2. Mobile cleaning device; 21. Fixed frame; 22. Brake wheel; 23. Cleaning assembly; 231. Motor; 232. Screw rod; 233. Pump body; 234. Partition net; 235. L-shaped box; 236. Nozzle; 3. Sterilization treatment device; 31. Support plate; 32. Electric telescopic rod; 33. Sterilization lamp; 34. Quartz glass frame; 4. Spring lifting rod; 5. Loading frame assembly; 6. Loading bottom plate; 7. Rectangular plate assembly; 8. Pressure rod assembly. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0021] Example 1

[0022] See also Figure 1-4 The utility model provides the following technical solutions: a DNA synthesis column loading device, including a loading frame assembly 5, spring lifting rods 4 are installed on both sides of the loading frame assembly 5, a rectangular plate assembly 7 is installed above the two spring lifting rods 4, the bottom of the rectangular plate assembly 7 is slidably connected with a loading bottom plate 6, an electric lifting rod 1 is arranged above the rectangular plate assembly 7, a pressure rod assembly 8 is installed on the side of the electric lifting rod 1 close to the rectangular plate assembly 7, the loading frame assembly 5 and the electric lifting rod 1 are connected by a mobile cleaning device 2, and a sterilization treatment device 3 is arranged on the outside of the rectangular plate assembly 7.

[0023] Specifically, the mobile cleaning device 2 includes a fixed frame 21, brake wheels 22 and a cleaning assembly 23. The loading frame assembly 5 is connected to the electric lifting rod 1 through the fixed frame 21. A plurality of brake wheels 22 are installed under the fixed frame 21. Cleaning assemblies 23 are installed on both sides of the fixed frame 21 near the edges.

[0024] By adopting the above technical solution, the staff can move the position of the device to a certain extent through each brake wheel 22 when necessary, thereby reducing the difficulty of moving the device and alleviating the labor burden of the staff.

[0025] Specifically, the cleaning component 23 includes a motor 231, a screw rod 232, a pump body 233, an L-shaped box 235 and a nozzle 236. The motor 231 is installed on the inner side of the fixed frame 21 and on both sides of the rectangular plate component 7. The screw rod 232 is installed on the side of the motor 231 away from the rectangular plate component 7. The L-shaped box 235 is installed on the outer side of the screw rod 232 through a thread. The nozzle 236 is installed on the top of the L-shaped box 235 near one side of the motor 231, and the pump body 233 is installed above the L-shaped box 235.

[0026] By adopting the above technical solution, the device can perform certain cleaning work on the rectangular plate assembly 7 and other structures through the cooperation of the pump body 233 and the nozzle 236 when necessary, so as to better meet the working needs in different situations.

[0027] Specifically, the cleaning assembly 23 further includes a partition net 234 , and the partition net 234 is installed on the inner side of the liquid inlet end of the pump body 233 .

[0028] By adopting the above technical solution, the device can filter the water entering the pump body 233 through the partition 234 to a certain extent, thereby reducing the possibility of accidental damage to the pump body 233 due to external impurities.

[0029] When the present embodiment is used, when the device is needed to load the DNA synthesis column, the staff pushes the device, moves the device to the working position by moving the brake wheels 22 in the cleaning device 2, then pours the synthesis column filler on the rectangular plate assembly 7 and scrapes it flat, pulls out the loading bottom plate 6, starts the electric lifting rod 1 on the fixed frame 21, thereby driving the pressure rod assembly 8 to descend, and then presses the filler into the loading frame assembly 5, so as to carry out the loading work, operates the electric lifting rod 1 to drive the pressure rod assembly 8 back to the original position, takes out the loaded filler, and the staff respectively starts the motors 231 in the two cleaning assemblies 23, thereby driving the two screw rods 232 to rotate, and the screw rods 232 is threadedly connected to the L-shaped box 235, and the L-shaped box 235 is slidably connected to the fixed frame 21, so the two screw rods 232 drive the two L-shaped boxes 235 and the various nozzles 236 thereon to move to the required positions. The staff needs to connect the two pump bodies 233 to the external water source through pipes in advance. The staff starts the two pump bodies 233. Under the action of the two pump bodies 233, the water filtered by the two partitions 234 enters the two L-shaped boxes 235, and then sprays out from the various nozzles 236, thereby cleaning the rectangular plate assembly 7 and other structures. After cleaning, the two pump bodies 233 are closed, the work is completed, and the spring lifting rod 4 plays a connecting role.

[0030] Example 2

[0031] The difference between this embodiment and embodiment 1 is that the sterilization treatment device 3 includes a support plate 31, a sterilization lamp 33 and a quartz glass frame 34. The support plate 31 is installed on the inner side of the fixed frame 21 and on one side of the two spring lifting rods 4. The quartz glass frame 34 is arranged above the support plate 31 and on the outer side of the rectangular plate assembly 7. Multiple sterilization lamps 33 are installed in the side wall of the quartz glass frame 34.

[0032] By adopting the above technical solution, the device can perform certain sterilization treatment on structures such as the rectangular plate assembly 7 through the cooperation of structures such as the sterilization lamp 33 and the quartz glass frame 34 when necessary, thereby reducing the possibility of the rectangular plate assembly 7 and other structures being contaminated by bacteria and ensuring the normal operation.

[0033] Specifically, the sterilization device 3 further includes an electric telescopic rod 32 , and the support plate 31 and the quartz glass frame 34 are connected via the electric telescopic rod 32 .

[0034] By adopting the above technical solution, the device can adjust the height of each germicidal lamp 33 to a certain extent through the electric telescopic rod 32 when needed, thereby adjusting the sterilization range to a certain extent to better meet the working needs in different situations.

[0035] When this embodiment is used, when it is necessary to sterilize the rectangular plate assembly 7 and other structures, the electric telescopic rod 32 on the support plate 31 of the sterilization treatment device 3 is started, thereby driving the quartz glass frame 34 and other structures to rise to the required height, and then the various sterilization lamps 33 are started to sterilize the rectangular plate assembly 7 and other structures.

[0036] The structure and principle of the spring lifting rod 4, the loading frame assembly 5 composed of a synthetic column placing plate, a synthetic column loading groove, a synthetic column loading frame and a loading positioning ring, the loading bottom plate 6, the rectangular plate assembly 7 composed of a loading rectangular plate, a loading filling groove area, a connecting groove, a loading tube and a slide groove, and the pressure rod assembly 8 composed of a pressing plate and a loading cylindrical pressure rod in the utility model have been disclosed in a DNA synthesis column loading device disclosed in Chinese patent application No. 202022116113.1. The working principle is that when in use, the loading bottom plate is first passed through the slide groove set at the bottom end of the loading rectangular plate to block the bottom port of the loading tube, and then the synthetic column filler is poured into the loading filling groove area set on the loading rectangular plate, and the synthetic column filler is scraped flat with an instrument until each loading tube is filled with the synthetic column filler, and then the pressing plate, the loading cylindrical pressure rod, the buffer block and the telescopic spring, the telescopic The synthetic column loading and pressing component composed of a rod combination is placed in an installation groove arranged on a loading rectangular plate, and the arranged loading cylindrical pressing rod is arranged to correspond vertically to the loading tube, and then the orifice plate arranged in the synthetic column loading frame is fixed in the synthetic column loading groove, so that the loading positioning circular ring arranged on the synthetic column loading frame corresponds vertically, and then the synthetic column loading and pressing component is pressed down to retract the arranged telescopic rod, and at the same time, the loading rectangular plate is retracted by the arranged spring lifting rod, and when the loading bottom plate is pasted with the orifice plate arranged in the synthetic column loading frame, the loading bottom plate is then drawn out, and one end of the loading tube is inserted into the loading positioning circular ring by the downward pressure, and then the loading cylindrical pressing rod arranged on the pressing plate is used to make the synthetic column filler in the loading tube smoothly fall into the container arranged in the synthetic column loading frame, so that multiple DNA synthetic columns can be filled at the same time without cross contamination, and the use is simple, the efficiency is high, and no waste of filler is caused.

[0037] The structure and principle of the sterilization lamp 33 in the utility model have been disclosed in a power transmission mechanism of an electric laparoscopic stapler disclosed in Chinese patent application No. 202122604755.0. Its working principle is to use a lower mercury vapor pressure to emit two ultraviolet rays that are invisible to the naked eye. Its spectral lines mainly have two, one with a wavelength of 253.7 nanometers and the other with a wavelength of 185 nanometers. After the cells absorb the ultraviolet rays, they act on the genetic material in the cells. Through photochemical action, the energy of the ultraviolet rays can cause the genetic material to mutate, causing the bacteria to die immediately or be unable to reproduce, thereby achieving the purpose of sterilization.

[0038] The working principle and use process of the utility model are as follows: when the device is needed to load the DNA synthesis column, the staff pushes the device, moves the device to the working position by moving the brake wheels 22 in the cleaning device 2, then pours the synthesis column filler on the rectangular plate assembly 7 and scrapes it flat, pulls out the loading bottom plate 6, starts the electric lifting rod 1 on the fixed frame 21, thereby driving the pressure rod assembly 8 to descend, and then presses the filler into the loading frame assembly 5, so as to carry out the loading work, operates the electric lifting rod 1 to drive the pressure rod assembly 8 back to the original position, takes out the loaded filler, and the staff respectively starts the motors 231 in the two cleaning assemblies 23, thereby driving the two screw rods 232 to rotate, the screw rod 232 is threadedly connected to the L-shaped box 235, and the L-shaped box 235 is slidably connected to the fixed frame 21, so the two screw rods 23 2 drives the two L-shaped boxes 235 and the nozzles 236 thereon to move to the required positions. The staff needs to connect the two pump bodies 233 to the external water source through pipelines in advance. The staff starts the two pump bodies 233. Under the action of the two pump bodies 233, the water filtered by the two partitions 234 enters the two L-shaped boxes 235 and then sprays out from the nozzles 236, thereby cleaning the rectangular plate assembly 7 and other structures. After cleaning, the two pump bodies 233 are closed, the work is completed, and the spring lifting rod 4 plays a connecting role; when it is necessary to sterilize the rectangular plate assembly 7 and other structures, the electric telescopic rod 32 on the support plate 31 in the sterilization treatment device 3 is started, thereby driving the quartz glass frame 34 and other structures to rise to the required height, and then the various sterilization lamps 33 are started to sterilize the rectangular plate assembly 7 and other structures.

[0039] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A DNA synthesis column loading device, comprising a loading frame assembly, characterized in that: Spring lifting rods are installed on both sides of the loading rack assembly, a rectangular plate assembly is installed above the two spring lifting rods, the bottom of the rectangular plate assembly is slidably connected to the loading base plate, an electric lifting rod is arranged above the rectangular plate assembly, a pressure rod assembly is installed on the side of the electric lifting rod close to the rectangular plate assembly, the loading rack assembly and the electric lifting rod are connected by a mobile cleaning device, and a sterilization treatment device is arranged on the outside of the rectangular plate assembly.

2. A DNA synthesis column loading device according to claim 1, characterized in that: The mobile cleaning device includes a fixed frame, brake wheels and a cleaning assembly. The loading frame assembly is connected to the electric lifting rod through the fixed frame. A plurality of brake wheels are installed below the fixed frame. Cleaning assemblies are installed on both sides of the fixed frame near the edges.

3. A DNA synthesis column loading device according to claim 2, characterized in that: The cleaning assembly includes a motor, a screw, a pump body, an L-shaped box and a nozzle. The motor is installed on the inner side of the fixed frame and on both sides of the rectangular plate assembly. The screw is installed on the side of the motor away from the rectangular plate assembly. The L-shaped box is installed on the outer side of the screw through a thread. The nozzle is installed on the top of the L-shaped box near one side of the motor, and the pump body is installed above the L-shaped box.

4. A DNA synthesis column loading device according to claim 3, characterized in that: The cleaning component also includes a partition net, and the partition net is installed on the inner side of the liquid inlet end of the pump body.

5. A DNA synthesis column loading device according to claim 2, characterized in that: The sterilization treatment device includes a support plate, a sterilization lamp and a quartz glass frame. The support plate is installed on the inner side of the fixed frame and on one side of the two spring lifting rods. The quartz glass frame is arranged above the support plate and on the outer side of the rectangular plate assembly. Multiple sterilization lamps are installed in the side wall of the quartz glass frame.

6. A DNA synthesis column loading device according to claim 5, characterized in that: The sterilization treatment device also includes an electric telescopic rod, and the support plate and the quartz glass frame are connected by the electric telescopic rod.

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