Kit for targeted gene locus detection

Abstract

The utility model provides a targeted gene locus detection kit, and relates to the field of kits, the targeted gene locus detection kit comprises a kit, the upper end face of the kit is provided with a plurality of storage grooves, at least one groove wall of each storage groove is close to the outer wall of the kit, and two opposite groove walls of each storage groove are respectively provided with a fixed clamping plate and a movable clamping plate; the fixed clamping plate and the movable clamping plate are arc plates, the inner arc sides of the fixed clamping plate and the movable clamping plate are oppositely arranged, the movable clamping plate is slidably arranged on the groove wall of one side, close to the outer wall of the kit, of the storage groove, and the fixed clamping plate is fixedly connected to the groove wall of the opposite side of the storage groove; an elastic piece is arranged between the outer arc side of the movable clamping plate and the groove wall of the storage groove, and a guide structure for realizing stable sliding of the movable clamping plate in the storage groove is arranged between the movable clamping plate and the kit. The kit has the effect of effectively improving collision between the reagent tubes with too small diameters and the inner walls of the storage grooves formed in the surface of the kit.

Description

Technical Field

[0001] The present application relates to the technical field of kits, and in particular to a kit for detecting targeted gene sites. Background Art

[0002] A test kit is a box used to hold chemical reagents for detecting chemical components, drug residues, virus types, etc. It is generally used in hospitals, inspection and quarantine or pharmaceutical companies. A test kit for targeted gene locus detection is a test kit specifically used to detect specific gene loci. This test kit is usually based on specific molecular biology methods, such as PCR (polymerase chain reaction), fluorescence in situ hybridization, etc., to achieve accurate detection of target gene loci.

[0003] In the prior art, a kit for detecting targeted gene sites is usually in the shape of a box body, with a plurality of storage slots provided on the top of the box body, into which reagent tubes are inserted, thereby facilitating the collection and transfer of a large number of reagent tubes.

[0004] However, the structure of the existing reagent kit for targeted gene site detection is too simple. When one reagent kit is needed to summarize and transfer multiple reagent tubes of different specifications, the reagent tubes with a diameter smaller than the side length of the storage tank will swing back and forth in the storage tank, causing frequent collisions between the reagent tubes and the inner wall of the storage tank, causing the reagent tubes to break during the collisions. Utility Model Content

[0005] In order to improve the problem that small-sized reagent tubes are prone to shaking and the risk of collision in the test kit, the present application provides a test kit for targeted gene site detection.

[0006] The present application provides a kit for detecting targeted gene loci using the following technical solution:

[0007] A kit for detecting targeted gene sites, comprising a kit, wherein the upper end surface of the kit is provided with a plurality of storage slots, wherein at least one slot wall of the storage slot is close to the outer wall of the kit, and a fixed clamping plate and a movable clamping plate are respectively arranged on two opposite slot walls of the storage slot, wherein both the fixed clamping plate and the movable clamping plate are arc plates and their inner arc sides are arranged opposite to each other, wherein the movable clamping plate is slidably arranged on a slot wall of the storage slot close to the outer wall of the kit, and the fixed clamping plate is fixedly connected to the slot wall on the opposite side of the storage slot;

[0008] An elastic member is arranged between the outer arc side of the movable clamping plate and the wall of the storage slot, and a guiding structure for realizing the smooth sliding of the movable clamping plate in the storage slot is arranged between the movable clamping plate and the reagent box.

[0009] Furthermore, the guide structure includes a pull rod fixedly connected to the outer arc side of the movable clamping plate, and a through hole connected to the storage groove is opened through the outer wall of the reagent box, and the pull rod is arranged to pass through the through hole.

[0010] Furthermore, the cross section of the pull rod is polygonal, and the through hole is adapted to the cross section of the pull rod.

[0011] Furthermore, one end of the pull rod facing away from the movable clamp is fixedly connected to a limit plate, and the projection area of ​​the limit plate on the outer wall of the reagent box is larger than the perforated area.

[0012] Furthermore, a boss is fixedly connected to the outer arc side of the movable clamping plate, and the pull rod is fixedly connected to a side of the boss away from the movable clamping plate.

[0013] Furthermore, the guide structure includes a sliding block fixedly connected to the bottom of the movable splint, and the bottom wall of the storage slot is provided with a sliding groove arranged along the arrangement direction of the fixed splint and the movable splint, and the sliding block is slidably arranged in the sliding groove.

[0014] Furthermore, a plurality of rubber strips arranged along the axial direction are fixedly connected to the inner arc side of the movable clamping plate and / or the fixed clamping plate.

[0015] Furthermore, a guiding slope is provided on the inner arc side of the upper end of the movable clamping plate and / or the fixed clamping plate.

[0016] In summary, the present application includes at least one of the following beneficial technical effects:

[0017] 1. After multiple storage slots are set in the reagent kit, the movable clamp is set on the side close to the outer wall of the reagent kit, so that the movable clamp can be conveniently used to fix and clamp reagent tubes of different diameters under the deformation force of the elastic member, which can effectively prevent the collision between the reagent tube with too small diameter and the inner wall of the storage slot set on the surface of the reagent kit, resulting in the damage of the reagent tube;

[0018] 2. The setting of the pull rod and the perforation, as well as the setting of the slider and the slide groove, helps the movable splint to move stably when clamping the reagent tube, so as to ensure that the movable splint can clamp the reagent tube on the fixed splint with a larger contact area;

[0019] 3. Multiple rubber strips are arranged on both sides of the top of the inner arc side of the movable splint and / or the fixed splint, which can increase the static friction between the reagent tube and the movable splint or the fixed splint to reduce the probability of the reagent tube shaking after being clamped, and increase the contact area between the small-sized reagent tube and the movable splint or the fixed splint to avoid shaking caused by the small contact area between the small-sized reagent tube and the movable splint or the fixed splint. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the technical solutions in the present invention or the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0021] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the present application;

[0022] Figure 2 is a schematic diagram of a partial cross-sectional structure of an embodiment of the present application;

[0023] Figure 3 yes Figure 2 A magnified schematic diagram of part A;

[0024] Figure 4 It is a schematic diagram of the structure of the movable splint and the fixed splint of the fifth embodiment of the present application.

[0025] Figure numerals: 1. reagent box; 2. storage slot; 3. fixed splint; 4. movable splint; 5. reagent tube; 6. boss; 7. pull rod; 8. perforation; 9. elastic member; 10. limit plate; 11. slide groove; 12. slider; 13. rubber strip; 14. guide slope. DETAILED DESCRIPTION

[0026] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the drawings of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0027] Embodiment 1

[0028] See also Figures 1 to 3 The utility model provides a reagent kit for detecting targeted gene sites, which includes a reagent kit 1. A plurality of storage slots 2 are provided on the surface of the reagent kit 1. The plurality of storage slots 2 are distributed in a rectangular array on the reagent kit 1, and at least one slot wall of the storage slot 2 is close to the outer wall of the reagent kit 1. A fixed splint 3 and a movable splint 4 are respectively provided on two opposite slot walls of the storage slot 2. Both the fixed splint 3 and the movable splint 4 are arc plates and their inner arc sides are arranged oppositely. The movable splint 4 is slidably arranged on a slot wall of the storage slot 2 close to the outer wall of the reagent kit 1. The fixed splint 3 is fixedly connected to the slot wall on the opposite side of the storage slot 2. The fixed splint 3 and the movable splint 4 enclose a test tube cavity for inserting a reagent tube 5.

[0029] An elastic member 9 is arranged between the outer arc side of the movable splint 4 and the wall of the storage slot 2. The elastic member 9 is specifically arranged as a spring with one end fixed to the movable splint 4 and the other end fixed to the wall of the storage slot 2. A guide structure for realizing smooth sliding of the movable splint 4 in the storage slot 2 is arranged between the movable splint 4 and the reagent kit 1.

[0030] In actual use, first move the movable splint 4 to make it slide in the storage slot 2 to the side away from the fixed splint 3, and the movement of the movable splint 4 compresses the elastic member 9, and then put the reagent tube 5 into the storage slot 2, and then slowly release the movable splint 4, and the movable splint 4 is pushed toward the fixed splint 3 under the elastic action of the elastic member 9, and finally the reagent tube 5 is clamped between the fixed splint 3 and the movable splint 4, and the storage of the reagent tube 5 can be completed. The elastic action of the elastic member 9 generates a thrust toward the fixed splint 3 on the movable splint 4, so that reagent tubes 5 of various diameters can be clamped between the fixed splint 3 and the movable splint 4, which can effectively avoid the collision between the reagent tube 5 with too small diameter and the inner wall of the storage slot 2 set on the surface of the reagent kit 1, resulting in the damage of the reagent tube 5.

[0031] Embodiment 2

[0032] Based on the first embodiment, the present embodiment is different from the first embodiment in that:

[0033] See also Figure 2 and Figure 3 In order to increase the force bearing area of ​​the elastic member 9 on the movable splint 4, a boss 6 is provided at the end of the movable splint 4 away from the fixed splint 3, one end of the elastic member 9 is fixed on the boss 6, and the other end is fixed on the groove wall of the storage groove 2 close to the outer wall of the reagent box 1.

[0034] The reason for such arrangement is that the end of the movable clamping plate 4 away from the fixed clamping plate 3 is a curved surface. If the elastic member 9 is directly arranged between the movable clamping plate 4 and the inner wall of the reagent box 1, the thrust exerted by the elastic member 9 on the movable clamping plate 4 is too concentrated, which is not conducive to the stable clamping of the reagent tube 5 by the movable clamping plate 4. By arranging the boss 6 at the end of the movable clamping plate 4 away from the fixed clamping plate 3, the elastic member 9 is arranged between the boss 6 and the inner wall of the reagent box 1, and the contact surface between the boss 6 and the elastic member 9 is a plane, so that the force area of ​​the elastic member 9 on the movable clamping plate 4 is increased.

[0035] Embodiment 3

[0036] Based on the second embodiment, the difference between this embodiment and the second embodiment is that:

[0037] See also Figure 2 and Figure 3In order to facilitate the manipulation of the movable splint 4, the aforementioned guide structure includes a pull rod 7 fixed to the outer arc side of the movable splint 4. A through hole 8 connected to the storage slot 2 is provided on the outer peripheral wall of the reagent box 1. The pull rod 7 is movably inserted in the through hole 8. The cross section of the pull rod 7 is polygonal, and the through hole 8 is adapted to the cross section of the pull rod 7. Specifically, the through hole 8 is a rectangular hole, and the pull rod 7 is a rectangular rod structure. One end of the pull rod 7 is fixed on the surface of the boss 6, and a limit plate 10 is fixed on the end of the pull rod 7 away from the boss 6. The projection area of ​​the limit plate 10 on the outer wall of the reagent box 1 is larger than the area of ​​the through hole 8. Specifically, the limit plate 10 is a circular plate, and the diameter of the limit plate 10 is larger than the side length of the through hole 8.

[0038] When the movable splint 4 is moved in the direction away from the fixed splint 3, it is only necessary to pull the limit plate 10 in the direction away from the fixed splint 3. The limit plate 10 drives the movable splint 4 to move in the direction away from the fixed splint 3 through the pull rod 7 and the boss 6. When the movable splint 4 is moved in the direction close to the fixed splint 3, continue to pull the limit plate 10 and slowly reduce the force used to pull the limit plate 10, so that the movable splint 4 can slowly move in the direction close to the fixed splint 3 under the thrust of the elastic member 9. At the same time, the diameter of the limit plate 10 is larger than the side length of the through hole 8, which can prevent the pull rod 7 from being completely ejected from the through hole 8.

[0039] Embodiment 4

[0040] Based on the third embodiment, the present embodiment is different from the third embodiment in that:

[0041] See also Figure 2 In order to further achieve smooth guidance of the movement direction of the movable splint 4, the guide structure also includes a slider 12 fixed to the bottom of the movable splint 4, and the bottom wall of the storage slot 1 is provided with a slide groove 11 arranged along the arrangement direction of the fixed splint 3 and the movable splint 4. The slider 12 is slidably arranged in the slide groove 11, and the slider 12 is a rectangular block structure.

[0042] By opening a slide groove 11 at the bottom end of the inner wall of the storage groove 2, fixing a slider 12 at the bottom end of the movable splint 4, and allowing the slider 12 to slide in the slide groove 11, the movement direction of the movable splint 4 can be guided to prevent it from lateral displacement, resulting in loose clamping of the reagent tube 5.

[0043] Embodiment 5

[0044] Based on the first embodiment, the present embodiment is different from the first embodiment in that:

[0045] See also Figure 4A plurality of rubber strips 13 arranged along the axial direction are fixedly connected to the inner arc side of the movable splint 4 and / or the fixed splint 3, and the plurality of rubber strips 13 are distributed at intervals on the arc surface of the movable splint 4 and / or the fixed splint 3; in this way, on the one hand, the setting of the rubber strips 13 can increase the static friction between the reagent tube 5 and the movable splint 4 or the fixed splint 3, so as to reduce the probability of the reagent tube 5 shaking after being clamped; on the other hand, the setting of the plurality of rubber strips 13 can increase the contact area between the small-sized reagent tube 5 and the movable splint 4 or the fixed splint 3, so as to avoid shaking caused by the small-sized reagent tube 5 and the movable splint 4 or the fixed splint 3.

[0046] Therefore, it is necessary to further explain that the rubber strip 13 shall not be provided at the top of the arc on the inner arc side of the movable splint 4 and / or the fixed splint 3, and the plurality of rubber strips 13 shall be distributed at intervals on both sides of the top of the arc, so that the rubber strip 13 can effectively increase the contact area between the reagent tube 5 and the movable splint 4 or the fixed splint 3; and the width of the plurality of rubber strips 13 gradually increases from the top of the arc on the inner arc side of the movable splint 4 or the fixed splint 3 to its edge portion.

[0047] On the other hand, in order to facilitate the insertion of the reagent tube 5 between the movable splint 4 and the fixed splint 3, a guide slope 14 is provided on the inner arc side of the upper end of the movable splint 4 and / or the fixed splint 3. By setting the guide slope 24, there is no need to manually drive the movable splint 4 away from the fixed splint 3 when installing the reagent tube 5, which can improve the convenience of use.

[0048] Specifically in this example, a plurality of rubber strips 13 are provided on the movable clamping plate 4 , and a guiding inclined surface 24 is provided on the fixed clamping plate 3 .

[0049] The working principle of a kit for detecting targeted gene sites in the embodiment of the present application is as follows:

[0050] In actual use, first move the movable splint 4 so that the movable splint 4 slides in the storage slot 2 to the side away from the fixed splint 3. The movement of the movable splint 4 compresses the elastic member 9, and then the reagent tube 5 is placed in the storage slot 2. Then, slowly release the movable splint 4. The movable splint 4 is pushed toward the fixed splint 3 under the elastic action of the elastic member 9, and finally the reagent tube 5 is clamped between the fixed splint 3 and the movable splint 4, and the storage of the reagent tube 5 is completed. The elastic action of the elastic member 9 generates a thrust toward the fixed splint 3 on the movable splint 4, so that reagent tubes 5 of various diameters can be clamped between the fixed splint 3 and the movable splint 4, which can effectively improve the situation that the reagent tube 5 with too small diameter collides with the inner wall of the storage slot 2 set on the surface of the reagent kit 1, resulting in the damage of the reagent tube 5.

[0051] And by arranging a boss 6 at one end of the movable splint 4 away from the fixed splint 3, the elastic member 9 is arranged between the boss 6 and the inner wall of the reagent box 1, and the contact surface between the boss 6 and the elastic member 9 is a plane, so that the force area of ​​the elastic member 9 on the movable splint 4 is increased; when the movable splint 4 moves in the direction away from the fixed splint 3, it is only necessary to pull the limit plate 10 in the direction away from the fixed splint 3, and the limit plate 10 drives the movable splint 4 to move in the direction away from the fixed splint 3 through the pull rod 7 and the boss 6. When the movable splint 4 moves in the direction close to the fixed splint 3, Continue to hold the limit plate 10 and slowly reduce the force used to pull the limit plate 10, so that the movable splint 4 can slowly move toward the fixed splint 3 under the thrust of the elastic member 9. At the same time, the diameter of the limit plate 10 is larger than the side of the through hole 8, which can prevent the pull rod 7 from being completely ejected from the through hole 8. By providing a slide groove 11 at the bottom end of the inner wall of the storage groove 2, fixing a slider 12 at the bottom end of the movable splint 4, and allowing the slider 12 to slide in the slide groove 11, the movement direction of the movable splint 4 can be guided to prevent it from lateral displacement, resulting in a loose clamping of the reagent tube 5.

[0052] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A kit for detecting targeted gene loci, comprising a kit, wherein the upper end surface of the kit is provided with a plurality of storage slots, characterized in that: The storage slot has at least one slot wall close to the outer wall of the reagent kit, and two opposite slot walls of the storage slot are respectively provided with a fixed clamping plate and a movable clamping plate, the fixed clamping plate and the movable clamping plate are both arc plates, and the inner arc sides of the two are arranged opposite to each other, the movable clamping plate is slidably arranged on one side of the slot wall of the storage slot close to the outer wall of the reagent kit, and the fixed clamping plate is fixedly connected to the slot wall on the opposite side of the storage slot; An elastic member is arranged between the outer arc side of the movable clamping plate and the wall of the storage slot, and a guiding structure for realizing the smooth sliding of the movable clamping plate in the storage slot is arranged between the movable clamping plate and the reagent box.

2. A kit for detecting targeted gene sites according to claim 1, characterized in that: The guide structure comprises a pull rod fixedly connected to the outer arc side of the movable clamping plate, a through hole connected to the storage groove is formed through the outer wall of the reagent box, and the pull rod is arranged through the through hole.

3. A kit for detecting targeted gene sites according to claim 2, characterized in that: The cross section of the pull rod is polygonal, and the through hole is adapted to the cross section of the pull rod.

4. A kit for detecting targeted gene sites according to claim 3, characterized in that: One end of the pull rod away from the movable clamp is fixedly connected to a limiting plate, and a projection area of ​​the limiting plate on the outer wall of the reagent box is larger than the perforated area.

5. A kit for detecting targeted gene sites according to claim 2, characterized in that: A boss is fixedly connected to the outer arc side of the movable clamping plate, and the pull rod is fixedly connected to a side of the boss away from the movable clamping plate.

6. A kit for detecting targeted gene sites according to any one of claims 1 to 5, characterized in that: The guide structure comprises a sliding block fixedly connected to the bottom of the movable clamping plate, the bottom wall of the storage slot is provided with a sliding groove arranged along the arrangement direction of the fixed clamping plate and the movable clamping plate, and the sliding block is slidably arranged in the sliding groove.

7. A kit for detecting targeted gene sites according to claim 1, characterized in that: A plurality of rubber strips arranged along the axial direction are fixedly connected to the inner arc side of the movable clamping plate and / or the fixed clamping plate.

8. A kit for detecting targeted gene sites according to claim 1, characterized in that: The inner arc side of the upper end of the movable clamping plate and / or the fixed clamping plate is provided with a guiding inclined surface.

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