Stirring and mixing device for polypeptide reagent production
By designing an adjustable powder and fluid hopper, as well as a combination of feed tube and buffer ring plate, the problem of raw material stickiness and residue in the production of peptide reagents is solved, and more efficient raw material mixing and equipment cleaning are achieved.
Patent Information
- Application Number
- CN202420960822.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-07
- Publication Date
- 2025-01-21
- Estimated Expiration
- 2034-05-07
AI Technical Summary
During the production process of peptide reagents, powdered and liquid raw materials are prone to stick in the hopper, making it difficult to clean up, and may bring in residual other raw materials when injecting materials, affecting the mixing effect.
A stirring and mixing device for the production of peptide reagents is designed, including a powder hopper and a fluid hopper that can be adjusted up and down. Through the design of the feed pipe and buffer ring plate, the classified injection and shock absorption effect of raw materials are achieved, and the residual and viscous raw materials are reduced. The probability of stickiness.
It effectively avoids the sticking and residue of raw materials in the hopper, reduces the problems of raw materials being brought into each other and uneven mixing, improves the mixing efficiency of raw materials, and simplifies the cleaning process of the equipment.
Smart Images
Figure CN222368991U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of mixing devices, in particular to a stirring and mixing device for producing polypeptide reagents. Background Art
[0002] Peptides are compounds formed by α-amino acids linked together by peptide bonds. They are intermediate products of protein hydrolysis. Compounds formed by dehydration and condensation of two amino acid molecules are called dipeptides, and peptides composed of three or more amino acid molecules are called polypeptides. Polypeptide reagents are reagent materials used for polypeptides. During production, polypeptide reagents need to be stirred using a mixing device to accelerate the mixing of various raw materials. The raw materials of polypeptide reagents are mostly powdered raw materials and some liquid and fluid raw materials. These raw materials are injected into the mixing tank one after another through the same hopper. Therefore, the raw materials remaining in the injection hopper are easy to stick to each other, and then attached to the hopper and difficult to clean. At the same time, when stirring the raw materials for different types of polypeptides, other raw materials remaining from the previous time may be brought in during injection, thereby affecting the normal mixing of the raw materials and causing inconvenience. Utility Model Content
[0003] The main purpose of the utility model is to provide a stirring and mixing device for producing polypeptide reagents, which can effectively solve the problems in the background technology.
[0004] In order to achieve the above purpose, the technical solution adopted by the utility model is:
[0005] A stirring and mixing device for producing polypeptide reagents comprises a tank body, a stand is arranged at the bottom position of the outer circle of the tank body, a motor is arranged at the bottom of the tank body, a top plate is arranged on the upper end surface of the tank body, a material trough is arranged in the middle of the top plate, a plurality of oblique support rods are arranged on the upper end surface of the top plate, a support plate is arranged on the top of the oblique support rods, seat plates that can be adjusted up and down are arranged on both sides of the upper end surface of the support plate, and a powder hopper and a fluid hopper that can be adjusted up and down are respectively arranged above the seat plate.
[0006] Preferably, the support plate and the diagonal support rod are fixed by welding, and the powder hopper and the fluid hopper are both located above the trough.
[0007] Preferably, a feed pipe is provided at the bottom of the powder hopper and the fluid hopper, a fixed ring plate is provided at the top position of the outer circle of the feed pipe, a buffer ring plate is provided at the bottom position of the outer circle of the feed pipe, the buffer ring plate and the feed pipe are movably connected, a buffer spring is provided between the buffer ring plate and the fixed ring plate, and the buffer spring is located at the outer circle position of the feed pipe.
[0008] Preferably, a docking hole is provided on the upper end surface of the seat plate, the diameter of the docking hole is equal to the outer diameter of the feed pipe, the tail end of the feed pipe extends into the docking hole, and the buffer ring plate is located above the seat plate.
[0009] Preferably, a fixed block is provided in the middle position of the lower end surface of the seat plate, a fixing groove is provided on the upper end surface of the support plate corresponding to the fixed block, additional blocks are provided on both side end surfaces of the fixed block, and positioning marbles are provided on the outer end surfaces of the additional blocks, side grooves are provided on the inner walls on both sides of the fixing groove corresponding to the additional blocks, and positioning grooves are provided on the rear walls of the side grooves corresponding to the positioning marbles.
[0010] Preferably, an outer circular hole is provided on the outer end face of the additional block corresponding to the locking ball, an inner circular groove is provided behind the outer circular hole, the bottom of the locking ball extends into the inner circular groove and is provided with a movable circular plate, an inner circular plate is provided on the rear wall of the inner circular groove, and a reset spring is provided between the movable circular plate and the inner circular plate.
[0011] Compared with the prior art, the utility model has the following beneficial effects:
[0012] In the utility model, a support plate and a pair of base plates are arranged above the top plate, and then a powder hopper and a fluid hopper that can be adjusted up and down are installed, so that the raw materials for the polypeptide reagent are injected according to classification, so as to avoid different types of raw materials sticking together and being difficult to clean. The hopper is detachable so that it can be quickly disassembled for cleaning. At the same time, a buffer ring plate is arranged on the outer ring of the feed pipe to provide a certain shock absorption effect, so as to avoid the raw materials splashing and being difficult to clean when falling. Different injection hoppers are arranged according to the different properties of the polypeptide raw materials, so as to effectively reduce the probability of raw materials remaining and sticking to each other, and avoid the situation where raw materials remain and are difficult to clean. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 It is a schematic diagram of the overall structure of the utility model;
[0014] Figure 2 This is a schematic diagram of a feed pipe of the utility model;
[0015] Figure 3 It is a schematic diagram of a fixing block of the utility model;
[0016] Figure 4 This is a schematic diagram of the additional block splitting of the utility model.
[0017] In the figure: 1. tank body; 2. motor; 3. stand; 4. top plate; 5. trough; 6. diagonal support rod; 7. support plate; 8. seat plate; 9. powder hopper; 10. docking hole; 11. feed pipe; 12. fixed ring plate; 13. buffer ring plate; 14. buffer spring; 15. fixed block; 16. additional block; 17. fixed groove; 18. side groove; 19. positioning marbles; 20. positioning groove; 21. outer circular hole; 22. inner circular groove; 23. movable circular plate; 24. reset spring; 25. built-in circular plate; 26. fluid hopper. DETAILED DESCRIPTION
[0018] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.
[0019] like Figure 1-4 As shown, a stirring and mixing device for producing polypeptide reagents comprises a tank body 1, a stand 3 is arranged at the bottom position of the outer ring of the tank body 1, a motor 2 is arranged at the bottom of the tank body 1, a top plate 4 is arranged on the upper end surface of the tank body 1, a material trough 5 is arranged in the middle of the top plate 4, a plurality of inclined support rods 6 are arranged on the upper end surface of the top plate 4, a support plate 7 is arranged on the top of the inclined support rods 6, seat plates 8 which can be adjusted up and down are arranged on both sides of the upper end surface of the support plate 7, and a powder hopper 9 and a fluid hopper 26 which can be adjusted up and down are arranged above the seat plate 8 respectively.
[0020] In this embodiment, in order to provide a certain buffering and shock absorption when the raw materials fall and reduce the splashing of the raw materials, the support plate 7 and the diagonal support rod 6 are fixed by welding, the powder hopper 9 and the fluid hopper 26 are both located above the material trough 5, and the powder hopper 9 and the fluid hopper 26 are both provided with a feed pipe 11 at the bottom, a fixed ring plate 12 is provided at the top of the outer circle of the feed pipe 11, and a buffer ring plate 13 is provided at the bottom of the outer circle of the feed pipe 11. The buffer ring plate 13 and the feed pipe 11 are movably connected, and a buffer spring 14 is provided between the buffer ring plate 13 and the fixed ring plate 12, and the buffer spring 14 is located at the outer circle of the feed pipe 11. A docking hole 10 is provided on the upper end surface of the seat plate 8, and the diameter of the docking hole 10 is equal to the outer diameter of the feed pipe 11. The tail of the feed pipe 11 extends into the docking hole 10, and the buffer ring plate 13 is located above the seat plate 8;
[0021] In this embodiment, in order to be able to quickly disassemble and assemble the powder hopper 9, the fluid hopper 26 and the corresponding seat plate 8 for cleaning, a fixed block 15 is provided in the middle position of the lower end surface of the seat plate 8, and a fixed groove 17 is provided on the upper end surface of the support plate 7 corresponding to the fixed block 15, and additional blocks 16 are provided on the end surfaces on both sides of the fixed block 15. The outer end surface of the additional block 16 is provided with a locking ball 19, and the inner walls on both sides of the fixed groove 17 are provided with side grooves 18 corresponding to the additional block 16, and the rear wall of the side groove 18 is provided with a locking groove 20 corresponding to the locking ball 19, the outer end surface of the additional block 16 is provided with an outer circular hole 21 corresponding to the locking ball 19, and an inner circular groove 22 is provided behind the outer circular hole 21. The bottom of the locking ball 19 extends into the inner circular groove 22 and is provided with a movable circular plate 23, and the rear wall of the inner circular groove 22 is provided with a built-in circular plate 25, and a reset spring 24 is provided between the movable circular plate 23 and the built-in circular plate 25.
[0022] It should be noted that the utility model is a stirring and mixing device for the production of polypeptide reagents. In actual use, various raw materials required for the polypeptide reagents are first prepared, and a suitable injection hopper is selected according to different raw material categories. The powder material is injected along the powder hopper 9, so that it falls through the feed pipe 11 and finally enters the bottom of the material tank 5, and then the fluid and liquid materials are injected through the fluid hopper 26, so that it also enters the bottom of the material tank 5. In the process of raw material injection, the raw materials will impact the powder hopper 9 and the fluid hopper 26 when they fall, causing them to move downward, thereby driving the feed pipe 11 below to move downward. When the feed pipe 11 moves, the buffer ring plate 13 of its outer ring is blocked by the seat plate 8, so that it moves relative to the feed pipe 11, thereby squeezing the connected buffer spring 14, causing it to be compressed by force. The elastic force of the buffer spring 14 can reduce the impact of the raw materials to a certain extent, and reduce the probability of the raw materials splashing. After the raw material injection is completed, the mixing device can be started for stirring to accelerate the mixing of the raw materials. By setting different injection speeds according to the different properties of the polypeptide raw materials, different injection speeds can be set. The hopper effectively reduces the probability of raw material residue and sticking to each other, and avoids the situation where raw materials remain and are difficult to clean. Furthermore, when different types of polypeptide reagent raw materials are stirred, the types of raw materials have changed. In order to avoid mixing raw materials, the powder hopper 9, fluid hopper 26 and seat plate 8 used last time can be cleaned. The powder hopper 9 and fluid hopper 26 can be directly lifted upward to drive the feed pipe 11 to rise, and then the seat plate 8 can be lifted to drive the fixed block 15 and the additional block 16 to move upward. The positioning marbles 19 on both sides of the additional block 16 follow the movement and are squeezed and contracted inward during movement. When the positioning marbles 19 contract, they drive the movable circular plate 23 to move inward, and the movable circular plate 23 squeezes the reset spring 24 to compress it until the positioning marbles 19 are completely contracted and detached from the positioning groove 20. Then the seat plate 8, fixed block 15 and additional block 16 can be removed, and then the removed related components can be thoroughly cleaned to avoid the residue of other raw materials. After cleaning, they can be installed again according to the same principle.
[0023] The above shows and describes the basic principle and main features of the utility model and the advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.
Claims
1. A stirring and mixing device for producing polypeptide reagents, comprising a tank body (1), a stand (3) is arranged at the bottom of the outer ring of the tank body (1), a motor (2) is arranged at the bottom of the tank body (1), a top plate (4) is arranged on the upper end surface of the tank body (1), and a material trough (5) is arranged in the middle of the top plate (4), characterized in that: The upper end surface of the top plate (4) is provided with a plurality of diagonal support rods (6), the top of the diagonal support rods (6) is provided with a support plate (7), both sides of the upper end surface of the support plate (7) are provided with seat plates (8) that can be adjusted up and down, and the upper part of the seat plate (8) is provided with a powder hopper (9) and a fluid hopper (26) that can be adjusted up and down.
2. The stirring and mixing device for producing a polypeptide reagent according to claim 1, characterized in that: The support plate (7) and the diagonal support rod (6) are fixed by welding, and the powder hopper (9) and the fluid hopper (26) are both located above the material trough (5).
3. The stirring and mixing device for producing a polypeptide reagent according to claim 1, characterized in that: A feed pipe (11) is provided at the bottom of the powder hopper (9) and the fluid hopper (26); a fixed ring plate (12) is provided at the top position of the outer ring of the feed pipe (11); a buffer ring plate (13) is provided at the bottom position of the outer ring of the feed pipe (11); the buffer ring plate (13) and the feed pipe (11) are movably connected; a buffer spring (14) is provided between the buffer ring plate (13) and the fixed ring plate (12); and the buffer spring (14) is located at the outer ring position of the feed pipe (11).
4. The stirring and mixing device for producing a polypeptide reagent according to claim 3, characterized in that: The upper end surface of the seat plate (8) is provided with a docking hole (10), the diameter of the docking hole (10) is equal to the outer diameter of the feed pipe (11), the tail end of the feed pipe (11) extends into the docking hole (10), and the buffer ring plate (13) is located above the seat plate (8).
5. The stirring and mixing device for producing a polypeptide reagent according to claim 1, characterized in that: A fixing block (15) is provided at the middle position of the lower end surface of the seat plate (8); a fixing groove (17) is provided on the upper end surface of the support plate (7) corresponding to the fixing block (15); additional blocks (16) are provided on both side end surfaces of the fixing block (15); a locking ball (19) is provided on the outer side end surface of the additional block (16); side grooves (18) are provided on the inner walls on both sides of the fixing groove (17) corresponding to the additional block (16); and a locking groove (20) is provided on the rear wall of the side groove (18) corresponding to the locking ball (19).
6. A stirring and mixing device for producing a polypeptide reagent according to claim 5, characterized in that: An outer circular hole (21) is provided on the outer end surface of the additional block (16) corresponding to the locking ball (19), an inner circular groove (22) is provided behind the outer circular hole (21), the bottom of the locking ball (19) extends into the inner circular groove (22) and is provided with a movable circular plate (23), a rear wall of the inner circular groove (22) is provided with an inner circular plate (25), and a return spring (24) is provided between the movable circular plate (23) and the inner circular plate (25).