PCR (Polymerase Chain Reaction) amplification instrument with replaceable supporting plate structure

Abstract

The utility model relates to the technical field of biomedical treatment, and discloses a PCR (Polymerase Chain Reaction) amplification instrument with a replaceable supporting plate structure, which comprises a PCR amplification instrument body, a working cavity is formed in the PCR amplification instrument body, a convex plate is fixedly mounted on the inner wall of the working cavity, and a supporting plate is arranged at the top of the convex plate; and the rectangular groove is formed in the inner wall of the working cavity, a mounting groove is formed in the rectangular groove, and a fixing plate is fixedly mounted in the mounting groove. According to the PCR amplification instrument, the PCR amplification instrument body is matched with the supporting plate with the insertion holes with different apertures, the gene detection requirements of samples in centrifugal tubes with different sizes and models are met, the test cost is reduced, the supporting plate is tightly pressed in the working cavity through the matched use of the movable plate, the spring and the check block, and the detection accuracy is improved. Therefore, the replacement and installation speed of the supporting plate is improved, and the installation stability of the supporting plate in the working cavity is guaranteed.

Description

Technical Field

[0001] The utility model relates to the technical field of biomedicine, and more specifically, to a PCR amplification instrument with a replaceable supporting plate structure. Background Art

[0002] PCR amplification instrument, also known as PCR gene amplification instrument or PCR nucleic acid amplification instrument, is an instrument that uses PCR (polymerase chain reaction) technology to amplify specific DNA. During the operation of the PCR amplification instrument, the stable installation of the support plate is crucial, which not only ensures the smooth progress of the PCR reaction, but also prevents sample displacement or contamination caused by vibration or temperature changes.

[0003] The common support plate installation methods currently have certain defects. Although the screw locking method is firm, the operation process is relatively cumbersome and requires tools such as screwdrivers, which increases the difficulty of replacing the support plate to a certain extent. Especially in laboratory environments, frequent replacement of support plates may lead to reduced operating efficiency and even increase the risk of sample contamination. Although the snap-on protrusion locking method seems convenient, it has many inconveniences in actual application. First of all, the design of the snap-on protrusion requires precise control of size and shape to ensure the matching degree with the support plate. Most importantly, after frequent use, the locking performance of the snap-on protrusion will gradually decrease, causing the support plate to loosen or fall off easily, thereby affecting the stability and accuracy of the PCR amplifier. Utility Model Content

[0004] In order to overcome the deficiencies of the prior art, the utility model provides a PCR amplification instrument with a replaceable support plate structure, which has the advantage of rapid assembly and disassembly of the support plate in biomedicine.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a PCR amplifier with a replaceable support plate structure, comprising a PCR amplifier body, a working chamber is provided inside the PCR amplifier body, a convex plate is fixedly installed on the inner wall of the working chamber, and a support plate is provided on the top of the convex plate;

[0006] A rectangular groove, wherein the rectangular groove is provided on the inner wall of the working chamber, a mounting groove is provided inside the rectangular groove, a fixed plate is fixedly installed inside the mounting groove, a movable plate is movably installed inside the rectangular groove, and a stopper is fixedly installed at one end of the movable plate;

[0007] A spring, wherein the spring is located between the fixed plate and the movable plate;

[0008] The insertion hole is opened on the surface of the support plate and penetrates the support plate.

[0009] As a preferred technical solution of the utility model, a rubber sleeve is provided on the inner wall of the insertion hole, and a supporting protrusion block is fixedly installed on the surface of the support plate, and the supporting protrusion blocks are symmetrically placed on both sides of the insertion hole.

[0010] As a preferred technical solution of the utility model, a leg is fixedly installed on the bottom of the PCR amplifier body, and there are four legs. Leg pads are fixedly installed on the bottom of the four legs.

[0011] As a preferred technical solution of the utility model, heat dissipation slots are provided on both sides of the PCR amplification instrument body, and the number of heat dissipation slots in each group is six.

[0012] As a preferred technical solution of the utility model, a PCR amplifier top cover is movably installed on the top of the PCR amplifier body, and the outer diameter value of the PCR amplifier top cover is greater than the inner diameter value of the working chamber.

[0013] As a preferred technical solution of the utility model, an observation window is fixedly installed on the surface of the top cover of the PCR amplification instrument, and the observation window is made of glass.

[0014] Compared with the prior art, the beneficial effects of the utility model are as follows:

[0015] 1. In the utility model, when the support plate moves downward, the block is subjected to pressure to make the movable plate enter the interior of the rectangular groove, and then the elastic potential energy is released by the spring to reset the block, and the block squeezes the support plate. Compared with the traditional device, this device matches a plurality of support plates with different aperture insertion holes through a PCR amplification instrument body, meets the gene detection needs of samples in centrifuge tubes of different sizes and models, reduces the test cost, and through the coordinated use of the movable plate, the spring and the block, the support plate is pressed tightly against the interior of the working chamber, thereby improving the speed of replacing and installing the support plate and ensuring the installation stability of the support plate in the working chamber.

[0016] 2. The utility model provides a rubber sleeve on the inner wall of the insertion hole, and fixedly installs supporting protrusions on the surface of the support plate, and the supporting protrusions are symmetrically placed on both sides of the insertion hole. The rubber sleeve and the supporting protrusions are used in coordination with each other, thereby improving the stability of centrifuge tube insertion, allowing the centrifuge tube to remain stable during the detection process, thereby improving the detection accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the structure of the utility model;

[0018] Figure 2 This is a schematic diagram of the structure of the utility model when viewed from above;

[0019] Figure 3This is a schematic diagram of the partial cross-sectional structure of the PCR amplification instrument of the utility model;

[0020] Figure 4 For this utility model Figure 3 A schematic diagram of the partially enlarged structure at center A;

[0021] Figure 5 For this utility model Figure 3 Schematic diagram of the local enlarged structure at point B in the middle.

[0022] In the figure: 1. PCR amplification instrument body; 2. working chamber; 3. convex plate; 4. support plate; 5. mounting groove; 6. fixed plate; 7. rectangular groove; 8. movable plate; 9. spring; 10. block; 11. insertion hole; 12. rubber sleeve; 13. supporting convex block; 14. PCR amplification instrument top cover; 15. observation window; 16. heat dissipation groove; 17. support leg; 18. leg pad. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0024] like Figures 1 to 5 As shown, the utility model provides a PCR amplifier with a replaceable support plate structure, comprising a PCR amplifier body 1, a working chamber 2 is provided inside the PCR amplifier body 1, a convex plate 3 is fixedly installed on the inner wall of the working chamber 2, and a support plate 4 is provided on the top of the convex plate 3;

[0025] A rectangular groove 7 is provided on the inner wall of the working chamber 2, a mounting groove 5 is provided inside the rectangular groove 7, a fixed plate 6 is fixedly installed inside the mounting groove 5, a movable plate 8 is movably installed inside the rectangular groove 7, and a stopper 10 is fixedly installed at one end of the movable plate 8;

[0026] Spring 9, spring 9 is located between the fixed plate 6 and the movable plate 8;

[0027] An insertion hole 11, which is formed on the surface of the support plate 4 and penetrates the support plate 4;

[0028] When in use, the support plate 4 is placed inside the working chamber 2 and moved downward to the surface of the convex plate 3. At the same time, the stopper 10 is squeezed by the force from above so that the movable plate 8 moves toward the inside of the rectangular groove 7. At this time, the spring 9 is in a compressed state. When the support plate 4 is completely placed on the surface of the convex plate 3, the spring 9 releases its elastic potential energy and pushes the movable plate 8 to move outward. Then the stopper 10 is reset and presses the support plate 4 tightly. When the support plate 4 needs to be replaced, it only needs to be lifted up and then a new support plate 4 is placed.

[0029] When the support plate 4 moves downward, the block 10 is subjected to pressure to make the movable plate 8 enter the interior of the rectangular groove 7, and then the elastic potential energy is released by the spring 9 to reset the block 10, and the block 10 squeezes the support plate 4. Compared with the traditional device, this device matches a plurality of support plates 4 with different aperture insertion holes 11 through a PCR amplification instrument body 1 to meet the gene detection needs of samples in centrifuge tubes of different sizes and models, thereby reducing the test cost, and through the coordinated use of the movable plate 8, the spring 9 and the block 10, the support plate 4 is pressed tightly against the interior of the working chamber 2, thereby improving the speed of replacing and installing the support plate and ensuring the stability of the support plate installation in the working chamber.

[0030] Among them, a rubber sleeve 12 is arranged on the inner wall of the insertion hole 11, and a support protrusion block 13 is fixedly installed on the surface of the support plate 4, and the support protrusion block 13 is symmetrically placed on both sides of the insertion hole 11;

[0031] A rubber sleeve 12 is provided on the inner wall of the insertion hole 11, and a supporting protrusion block 13 is fixedly installed on the surface of the support plate 4 and the supporting protrusion blocks 13 are symmetrically placed on both sides of the insertion hole 11. The rubber sleeve 12 and the supporting protrusion blocks 13 are used in coordination with each other, thereby improving the stability of the centrifuge tube insertion, allowing the centrifuge tube to remain stable during the detection process, thereby improving the detection accuracy.

[0032] Among them, a support leg 17 is fixedly installed at the bottom of the PCR amplification instrument body 1, and the number of the support legs 17 is four, and a leg pad 18 is fixedly installed at the bottom of each of the four support legs 17;

[0033] A support leg 17 is fixedly installed at the bottom of the PCR amplifier body 1, and there are four support legs 17. The four support legs 17 ensure the stability of the device when in use. Leg pads 18 are fixedly installed at the bottom of the four support legs 17. The downward pressure is dispersed by the leg pads 18, so that the device is more stable.

[0034] Wherein, heat dissipation slots 16 are provided on both sides of the PCR amplification instrument body 1, and the number of heat dissipation slots 16 in each group is six;

[0035] Heat dissipation slots 16 are provided on both sides of the PCR amplifier body 1. The components inside the PCR amplifier body 1 are cooled by two groups of heat dissipation slots 16 to avoid danger. Each group of heat dissipation slots 16 has six heat dissipation slots, which can achieve better heat dissipation effect.

[0036] A PCR amplification instrument top cover 14 is movably installed on the top of the PCR amplification instrument body 1, and the outer diameter value of the PCR amplification instrument top cover 14 is greater than the inner diameter value of the working chamber 2;

[0037] A PCR amplifier top cover 14 is movably installed on the top of the PCR amplifier body 1. The PCR amplifier top cover 14 isolates the working chamber 2 from the outside to prevent dust in the air from entering the inside of the working chamber 2. The outer diameter of the PCR amplifier top cover 14 is greater than the inner diameter of the working chamber 2, so that the isolation effect of the PCR amplifier top cover 14 is better.

[0038] Among them, an observation window 15 is fixedly installed on the surface of the top cover 14 of the PCR amplification instrument, and the observation window 15 is made of glass;

[0039] An observation window 15 is fixedly installed on the surface of the top cover 14 of the PCR amplifier. The staff observes the internal situation of the working chamber 2 through the observation window 15. The observation window 15 is made of glass, and the glass is transparent, which is just right for the staff to observe the interior of the working chamber 2.

[0040] The working principle and use process of this utility model:

[0041] When in use, the support plate 4 is placed inside the working chamber 2 and moved downward to the surface of the convex plate 3. At the same time, the stopper 10 is squeezed by the force from above so that the movable plate 8 moves toward the inside of the rectangular groove 7. At this time, the spring 9 is in a compressed state. When the support plate 4 is completely placed on the surface of the convex plate 3, the spring 9 releases its elastic potential energy and pushes the movable plate 8 to move outward. Then the stopper 10 resets and presses the support plate 4 tightly. When the support plate 4 needs to be replaced, it is only necessary to lift the support plate 4 upward and then place the new support plate 4 in.

[0042] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0043] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A PCR amplifier with a replaceable support plate structure, comprising a PCR amplifier body (1), characterized in that: A working chamber (2) is provided inside the PCR amplification instrument body (1), a convex plate (3) is fixedly mounted on the inner wall of the working chamber (2), and a support plate (4) is provided on the top of the convex plate (3); A rectangular groove (7), wherein the rectangular groove (7) is provided on the inner wall of the working chamber (2), a mounting groove (5) is provided inside the rectangular groove (7), a fixed plate (6) is fixedly installed inside the mounting groove (5), a movable plate (8) is movably installed inside the rectangular groove (7), and a stopper (10) is fixedly installed at one end of the movable plate (8); A spring (9), wherein the spring (9) is located between the fixed plate (6) and the movable plate (8); An insertion hole (11), wherein the insertion hole (11) is formed on the surface of the support plate (4) and penetrates the support plate (4).

2. A PCR amplification instrument with a replaceable support plate structure according to claim 1, characterized in that: A rubber sleeve (12) is provided on the inner wall of the insertion hole (11), and a support protrusion block (13) is fixedly installed on the surface of the support plate (4), and the support protrusion blocks (13) are symmetrically placed on both sides of the insertion hole (11).

3. The PCR amplification instrument with a replaceable support plate structure according to claim 1, characterized in that: A support leg (17) is fixedly mounted on the bottom of the PCR amplification instrument body (1), and there are four support legs (17). A leg pad (18) is fixedly mounted on the bottom of each of the four support legs (17).

4. The PCR amplification instrument with a replaceable support plate structure according to claim 1, characterized in that: Both sides of the PCR amplification instrument body (1) are provided with heat dissipation grooves (16), and the number of heat dissipation grooves (16) in each group is six.

5. The PCR amplification instrument with a replaceable support plate structure according to claim 1, characterized in that: A PCR amplification instrument top cover (14) is movably mounted on the top of the PCR amplification instrument body (1), and the outer diameter of the PCR amplification instrument top cover (14) is greater than the inner diameter of the working chamber (2).

6. The PCR amplification instrument with a replaceable support plate structure according to claim 5, characterized in that: An observation window (15) is fixedly mounted on the surface of the top cover (14) of the PCR amplification instrument, and the observation window (15) is made of glass.

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