Microsphere dripping machine
By designing a microsphere bead drop machine, combining the automatic matching rotation of the detection component and the liquid nitrogen tank, and the cooling function of the blowing component, the problem of freeze-dried diagnostic reagents during filling and storage is solved, achieving high efficiency , convenient production process.
Patent Information
- Application Number
- CN202420382662.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-02-29
- Publication Date
- 2025-02-21
- Estimated Expiration
- 2034-02-28
AI Technical Summary
During the filling and storage of existing lyophilized diagnostic reagents, there are problems such as rapid liquid evaporation, risk of chemical reactions and low production capacity, and the existing equipment has complex structure and inconvenient operation.
A micro-ball bead drip machine was designed, which directly connects the beads by setting up detection components and the rotation of the liquid nitrogen tank, without the need to control the rotation speed of the liquid bead needle and the liquid nitrogen tank respectively, which increases the convenience of operation; at the same time, by blowing Gas components accelerate liquid bead cooling and expand production capacity.
The production of lyophilized diagnostic reagents with more convenient operation and higher production capacity is achieved, avoiding the risk of rapid liquid evaporation and chemical reactions, and improving the efficiency and reliability of the equipment.
Smart Images

Figure CN222510907U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a micro-ball dropping machine. Background Art
[0002] Existing diagnostic reagents are divided into liquid and dry types. Liquid types need to be stored and transported at -20°C, and have a short shelf life, which can easily lead to diagnostic failure. Freeze-dried diagnostic reagents remove most of the water in the reagents, making them easier to store and have a longer shelf life. Because freeze-dried diagnostic reagents have extremely small filling volumes (10-50 microliters), conventional filling methods can easily cause rapid evaporation of the liquid and inactivate the product; and there is a risk of chemical reactions in liquid reagents during the pre-freezing stage.
[0003] The existing patent CN216557971U is a freeze-drying micro-core granulator, which has a relatively complex structure and a small output.
[0004] The existing patent CN212492982U is a bead dropper. The patent has a complex structure, and the pump can only be adjusted manually, so it is difficult to keep the dripping amount consistent.
[0005] The existing patent CN214973798U is a freeze-drying bead liquid device. The patent has low production capacity, fast liquid nitrogen consumption, and requires frequent addition of liquid nitrogen or removal of materials.
[0006] Therefore, a microsphere bead dropping machine is proposed to solve the above problems. Utility Model Content
[0007] The utility model aims to overcome the existing defects and provide a microsphere bead dropping machine with simple structure and high production capacity.
[0008] The technical solution to achieve the above-mentioned purpose is: a microsphere bead dropping machine, including a table top, a code disk is rotatably connected to the table top, the code disk is connected to a liquid nitrogen tank, and a basket is connected to the liquid nitrogen tank; a needle assembly for dripping liquid is connected to the table top; a blowing assembly for air drying is connected to the table top; and a detection assembly for detecting position is connected to the table top.
[0009] Preferably, a plurality of notches are provided at equal distances on the outer circle of the code disc, and each of the notches is located on the center line of the basket grid.
[0010] Preferably, the needle assembly includes a first pillar, the first pillar is connected to the table top, one end of the support plate is connected to the first pillar, the other end of the support plate extends to the top of the basket and is connected to the cylinder, the output end of the cylinder is connected to the needle fixing plate, and the needle is connected to the needle fixing plate.
[0011] Preferably, the blowing assembly includes a second pillar, the second pillar is connected to the table top, one end of a blowing head fixing plate is connected to the second pillar, and the other end of the blowing head fixing plate extends to the top of the basket and is connected to the blowing head.
[0012] Preferably, the detection component includes a detector fixing plate, the detector fixing plate is connected to the table top, the detector fixing plate is connected to a detector, and the detector is used to detect the position of the notch on the code disk.
[0013] Preferably, a heat-insulating layer is provided in the liquid nitrogen tank.
[0014] Preferably, the support plate is movably connected to the first support column.
[0015] Preferably, the blowing head fixing plate is movably connected to the second support column.
[0016] The beneficial effects of the utility model are as follows: the microsphere bead dropping machine directly links the detection component and the rotation of the liquid nitrogen tank with the bead dropping, and there is no need to separately control the rotation speed of the bead dropping needle and the liquid nitrogen tank, so the operation is more convenient; the blowing component can be used to blow air or spray liquid nitrogen to accelerate the cooling of the liquid beads; to expand the production capacity, it only needs to increase the number of needles and the number of basket circles, increase the number of basket grids and the gap of the code disk, so the operation is more convenient; the rotation speed of the liquid nitrogen tank is automatically matched with the bead dropping time. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 It is a schematic diagram of the microsphere bead dropping machine of the utility model;
[0018] Figure 2 It is a side view of the micro-ball dropping machine of the utility model;
[0019] Figure 3 It is a top view of the microball bead dropping machine of the utility model.
[0020] In the figure: 1. liquid nitrogen tank; 2. basket; 3. code disk; 4. detector; 5. first pillar; 6. second pillar; 7. support plate; 8. cylinder; 9. needle; 10. needle fixing plate; 11. air blowing head fixing plate; 12. table top; 13. detector fixing plate; 14. air blowing head; 15. notch. DETAILED DESCRIPTION
[0021] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings. In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inside", "outside" and the like indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.
[0022] The utility model will be further described below in conjunction with the accompanying drawings.
[0023] like Figure 1-3 As shown, a microsphere bead dropping machine includes a table top 12, the table top 12 is rotatably connected to a code disk 3, the code disk 3 is connected to a liquid nitrogen tank 1, the liquid nitrogen tank 1 is connected to a basket 2, and an insulation layer is provided in the liquid nitrogen tank 1; a needle assembly for dripping liquid is connected to the table top 12; a blowing assembly for air drying is connected to the table top 12; and a detection assembly for detecting position is connected to the table top 12.
[0024] Specifically, the needle assembly includes a first pillar 5, the first pillar 5 is connected to the table 12, the first pillar 5 is connected to one end of the support plate 7, and the support plate 7 is movably connected to the first pillar 5. The other end of the support plate 7 extends to the top of the basket 2 and is connected to the cylinder 8, the output end of the cylinder 8 is connected to the needle fixing plate 10, and the needle 9 is connected to the needle fixing plate 10.
[0025] Specifically, the blowing assembly includes a second support 6, the second support 6 is connected to the table 12, one end of the blowing head fixing plate 11 is connected to the second support 6, and the blowing head fixing plate 11 is movably connected to the second support 6. The other end of the blowing head fixing plate 11 extends to the top of the basket 2 and is connected to the blowing head 14.
[0026] Specifically, a plurality of notches 15 are provided at equal distances on the outer circle of the code disc 3, and each notch 15 is located on the center line of the grid of the basket 2. The detection assembly includes a detector fixing plate 13, the detector fixing plate 13 is connected to the table board 12, and the detector fixing plate 13 is connected to the detector 4, and the detector 4 is used to detect the position of the notch 15 on the code disc 3. The detector 4 can be an infrared sensor, which is an existing device, and the model can be FT-H10.
[0027] Specifically, the detector 4 transmits action signals such as droplets, cylinder vibration, and air blowing by detecting the notch 15 of the code disk 3; the code disk 3 rotates with the liquid nitrogen tank 1, and when the detector 4 detects the notch 15, the needle 9 drops a droplet of liquid, and the cylinder 8 also moves once. Each time the needle drops a droplet of liquid, it vibrates up and down with the cylinder to prevent the droplets from hanging on the pillow without dripping. At the same time, the air blowing head 14 blows air or sprays liquid nitrogen once. The air blowing head 14 blows air or sprays liquid nitrogen, which can accelerate the cooling of the droplets and shorten the sedimentation time of the droplets. The droplets complete sedimentation before the liquid nitrogen tank rotates for a full week. The detector 4 detects the notch 15 of the code disk, controls the needle 9 to drop liquid beads, and speeds up the rotation speed of the liquid nitrogen tank 1. The dripping speed is accelerated accordingly, and the production capacity is increased.
[0028] Specifically, the number of inner and outer circles of the basket 2 corresponds to the number of needles 9. To expand production capacity, the number of needles and the number of basket circles need to be increased, and the number of basket grids and the gaps in the code disc can be increased. Each grid of the basket can only hold one drop of liquid bead at most to prevent two drops of liquid bead from sticking together.
[0029] Specifically, by setting up the detection component and the rotation of the liquid nitrogen tank 1 to be directly linked to the bead dropping, there is no need to control the rotation speed of the bead dropping needle 9 and the liquid nitrogen tank 1 separately, and the operation is more convenient; by setting up the blowing component, air can be blown or liquid nitrogen can be sprayed to accelerate the cooling of the liquid beads; to expand the production capacity, it is only necessary to increase the number of needles and the number of basket circles, increase the number of basket grids and the code disk gap, and the operation is more convenient; the rotation speed of the liquid nitrogen tank is automatically matched with the bead dropping time.
[0030] In the embodiment, a controller is also included, the detector 4 is electrically connected to the controller, and the controller is electrically connected to the control cylinder 8, the needle 9 and the blowing head 14, respectively, and the movement is controlled by the controller. The controller is a conventional instrument, and the working principle, size and model are irrelevant to the function of the present application, so no further description is given, and they are all controlled by a remote control switch. The control mode is controlled by the controller, and the control circuit of the controller can be realized by simple programming by technicians in the field. The provision of power is also common knowledge in the field, and the present utility model is mainly used to protect mechanical devices, so the present utility model does not explain the control mode and circuit connection in detail.
[0031] The above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model is described in detail with reference to the above embodiments, ordinary technicians in this field should understand that they can still modify the technical solutions recorded in the above embodiments, or replace some or all of the technical features therein with equivalents. These modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the utility model.
Claims
1. A microsphere bead dropping machine, characterized in that: The invention comprises a table top (12), wherein a code disk (3) is rotatably connected to the table top (12), wherein the code disk (3) is connected to a liquid nitrogen tank (1), and wherein a basket (2) is connected inside the liquid nitrogen tank (1); wherein a needle assembly for dripping liquid is connected to the table top (12); wherein an air blowing assembly for air drying is connected to the table top (12); and wherein a detection assembly for detecting a position is connected to the table top (12).
2. The microsphere bead dropping machine according to claim 1, characterized in that: A plurality of notches (15) are provided at equal distances on the outer circle of the code disc (3), and each of the notches (15) is located on the center line of the grid of the basket (2).
3. The microsphere bead dropping machine according to claim 1, characterized in that: The needle assembly comprises a first pillar (5), the first pillar (5) is connected to the table top (12), one end of a support plate (7) is connected to the first pillar (5), the other end of the support plate (7) extends to the top of the basket (2) and is connected to a cylinder (8), the output end of the cylinder (8) is connected to a needle fixing plate (10), and the needle fixing plate (10) is connected to a needle (9).
4. The microsphere bead dropping machine according to claim 1, characterized in that: The blowing assembly comprises a second pillar (6), the second pillar (6) is connected to the table top (12), one end of a blowing head fixing plate (11) is connected to the second pillar (6), the other end of the blowing head fixing plate (11) extends to the top of the basket (2) and is connected to the blowing head (14).
5. The microsphere bead dropping machine according to claim 2, characterized in that: The detection component comprises a detector fixing plate (13), wherein the detector fixing plate (13) is connected to the table top (12), and a detector (4) is connected to the detector fixing plate (13), wherein the detector (4) is used to detect the position of the notch (15) on the code disk (3).
6. The microsphere bead dropping machine according to claim 1, characterized in that: A heat-insulating layer is provided in the liquid nitrogen tank (1).
7. The microsphere bead dropping machine according to claim 3, characterized in that: The support plate (7) is movably connected to the first support column (5).
8. The microsphere bead dropping machine according to claim 4, characterized in that: The air blowing head fixing plate (11) is movably connected to the second support column (6).