Sterile delivery bag and sterile delivery device comprising same
By designing sterile delivery bags and sterile delivery devices, the problems of small quantity, long time, high cost and polluting the environment in the existing sterile delivery methods are solved, and efficient and safe delivery of sterile materials is achieved.
Patent Information
- Application Number
- CN202421426705.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-21
- Publication Date
- 2025-02-25
- Estimated Expiration
- 2034-06-21
AI Technical Summary
The existing sterile delivery methods have problems such as small number of transmissions, long time, high cost and possible pollution of the environment.
A sterile transfer bag is designed with a flexible storage space, the second end is sealed with a passive valve cover, the first end is open for putting in the material, and sterile state is formed by irradiation sterilization. At the same time, a sterile delivery device is provided, including a sterile delivery bag and an active valve cover installed in a sterile isolation chamber. The active valve cover can be coupled with the passive valve cover to achieve sealing opening.
The sterile delivery of materials is achieved through sterile delivery bags, shortening the delivery time, reducing costs, and avoiding external pollution. The use of sterile delivery devices makes the delivery process more efficient and safe.
Smart Images
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Abstract
Description
Technical Field
[0001] The utility model relates to the field of laboratory equipment, in particular to a sterile transfer bag and a sterile transfer device comprising the same. Background Art
[0002] In the process of experiment, sampling or production of life science products, sterile transportation and delivery are required throughout the process to ensure their quality. Usually, life science products are delivered in pre-filled plates. Currently, sterile transfer chambers are usually used to deliver pre-filled plates. The pre-filled plates are placed in the transfer chamber and sterilized by vaporized hydrogen peroxide (VHP) before delivery.
[0003] However, this delivery method has a small amount of delivery and a long time, and requires disinfection during delivery, which increases the cost of delivery. In addition, the disinfectant used may pollute the environment and even affect the quality of the pre-filled plates. Utility Model Content
[0004] In view of this, the utility model provides a sterile transfer bag and a sterile transfer device including the same, so as to solve or at least alleviate one or more of the above-mentioned problems and other problems existing in the prior art.
[0005] In order to achieve the aforementioned objectives, the first aspect of the utility model provides a sterile transfer bag, wherein the sterile transfer bag has a flexible storage space, the storage space is open at a first end, and the storage space is sealed and closed at a second end by a passive valve cover, and the passive valve cover has a fixing member sealedly connected to the storage space, and a sealing cover that can be detached from the sealing connection with the fixing member.
[0006] In the aforementioned sterile transfer bag, optionally, the fixing member comprises a connecting ring fixedly connected to the storage space and a clamping portion connected to the connecting ring; the inner periphery of the clamping portion is provided with a first flange;
[0007] The outer periphery of the sealing cover is provided with a first groove, which is suitable for clamping the first flange, and the first groove is also provided with a notch corresponding to the first flange, and the first flange can be moved in or out of the notch, so that the sealing cover is sealed closed or detached from the fixing member.
[0008] In the aforementioned sterile transfer bag, optionally, the first end of the storage space is heat-sealed or adhesively connected to the connecting ring of the fixing member.
[0009] In the sterile transfer bag as described above, optionally, the fixing member is connected to a handle, and the handle has a hand-holding portion and a connecting portion, one end of the connecting portion is connected to the connecting ring, and the hand-holding portion is connected to the other end of the connecting portion.
[0010] In the sterile transfer bag as described above, optionally, the connecting part is an L-shaped rod, one end of the L-shaped rod is fixedly connected to the connection between the connecting ring and the clamping part, the other end of the L-shaped rod is connected to the hand-held part, and the end of the hand-held part extends away from the storage space.
[0011] In the aseptic transfer bag as described above, optionally, the outer periphery of the clamping portion is provided with a second groove, the sealing cover has a central groove, and the inner periphery of the central groove is provided with a second flange.
[0012] In the sterile transfer bag as described above, optionally, the inner periphery of the fixing element is an oblique cut, and the outer periphery of the sealing cover is provided with an oblique cut surface corresponding to the oblique cut suitable for sealing and covering with the fixing element.
[0013] In order to achieve the aforementioned objectives, the second aspect of the utility model provides a sterile transfer device, which includes the sterile transfer bag as described in the first aspect, and an active valve cover, wherein the first end of the sterile transfer bag is sealed and closed, and the active valve cover is used to be installed on the wall of the sterile isolation cabin, and the active valve cover can be coupled with the passive valve cover and enable the sealing cover of the passive valve cover to detach from the fixing member and open.
[0014] In the aseptic transfer device as described above, optionally, the active valve cover includes a mounting member fixed to the wall of the aseptic isolation cabin and a coupling cover detachably connected to the mounting member;
[0015] A third groove is provided on the outer periphery of the mounting member, and the third groove is used to clamp the bulkhead of the isolation cabin. A fourth flange is provided on the inner periphery of the mounting member, and the fourth flange is used to clamp the fixing member of the passive valve cover of the sterile transfer bag.
[0016] The coupling cover is provided with a middle boss, and the periphery of the middle boss is provided with a third flange, and the third flange is used to be coupled to the sealing cover of the passive valve cover.
[0017] In the aseptic transfer device as described above, optionally, the active valve cover also includes a hinge mechanism and a locking mechanism, wherein the hinge mechanism is used to hinge the coupling cover to the mounting member; the locking mechanism includes a pressing portion located at the periphery of the coupling cover and an elastic handle, wherein the elastic handle is used to press or release the pressing portion.
[0018] The utility model provides an aseptic transfer bag, which has a flexible storage space. The second end of the flexible storage space is sealed and closed by a passive valve cover, and the first end of the flexible storage space is opened for placing materials that need to be aseptically transferred, such as pre-loaded flat dishes, and then the first end is sealed and closed, thereby the storage space is sealed and closed, and a sterile storage space is formed by irradiation sterilization. The materials in the storage space can be aseptically transferred through the aseptic transfer bag.
[0019] The utility model also provides an aseptic transfer device, which includes the above-mentioned aseptic transfer bag and an active valve cover installed in an aseptic transfer cabin. The active valve cover can be coupled with the passive valve cover of the aseptic transfer bag, and the passive valve cover can be sealed and opened to connect the storage space of the aseptic transfer bag with the aseptic transfer cabin, so that the material can be aseptically transferred from the aseptic transfer bag to the aseptic transfer cabin at one time, thereby shortening the transfer time to save the transfer cost. The entire transfer process is sealed to prevent external contamination. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] The disclosure of the present invention will become more apparent with reference to the accompanying drawings. It should be understood that these drawings are only for illustrative purposes and are not intended to limit the scope of protection of the present invention. In the drawings:
[0021] Figure 1 A schematic diagram of an embodiment of a sterile transfer bag of the utility model;
[0022] Figure 2 A schematic diagram of an active valve cover of an embodiment of a sterile transfer device of the utility model (a sterile isolation cabin is shown in the figure);
[0023] Figure 3 A schematic diagram of the coupling between an active valve cover and a passive valve cover of an embodiment of the aseptic transfer device of the utility model;
[0024] Figure 4 This is a schematic diagram of an active valve cover and a passive valve cover being opened after being coupled in an embodiment of the aseptic transfer device of the utility model.
[0025] Figure markings: 1-storage space; 10-sterile transfer bag; 11-first end; 12-second end; 2-passive valve cover; 3-fixing member; 31-connecting ring; 32-clamping part; 33-second groove; 34-first flange; 35-first groove; 36-bevel cut; 4-sealing cover; 41-center groove; 42-second flange; 43-bevel cut; 5-handle; 51-handling part; 52-connecting part; 6-active valve cover; 61-mounting member; 62-coupling cover; 63-third groove; 64-third flange; 65-middle boss; 66-lifting handle; 67-hinge mechanism; 68-locking mechanism; 69-fourth flange; 7-sterile isolation cabin; 71-cabin wall; 8-pressing part; 9-elastic handle. DETAILED DESCRIPTION
[0026] With reference to the accompanying drawings and specific embodiments, the structure, composition, features and advantages of the sterile transfer bag of the present invention and the sterile transfer device including the same will be described below in an exemplary manner. However, all descriptions should not be used to form any limitation on the present invention.
[0027] In addition, for any single technical feature described or implied in the embodiments mentioned in this document, or any single technical feature displayed or implied in the drawings, the present invention still allows for any combination or deletion of these technical features (or their equivalents) without any technical obstacles, and thus it should be considered that these more embodiments according to the present invention are also within the scope of the description in this document.
[0028] It should also be noted that the terms "inside", "outside", etc. indicate orientations or positional relationships based on the orientations or positional relationships of the sterile transfer bag shown in the accompanying drawings, and are only for the convenience of describing the present disclosure and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present disclosure.
[0029] In the description of the present disclosure, “plurality” means at least two, such as two, three or more, etc., unless otherwise clearly and specifically defined.
[0030] In addition, the terms "first", "second", "third", and "fourth" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first", "second", "third", and "fourth" may explicitly or implicitly include at least one of the features.
[0031] Figure 1 It is a schematic diagram of an embodiment of the sterile transfer bag of the utility model.
[0032] from Figure 1It can be seen that the sterile transfer bag 10 of the utility model includes a storage space 1 and a passive valve cover 2, wherein the storage space 1 has a first end 11 and a second end 12. When the passive valve cover 2 is opened, it is coupled with the active valve cover 6 and the active valve cover 6 (such as Figure 2 As shown) is actively guided to open, so that its storage space 1 is open to the outside, such as a sterile isolation cabin 7.
[0033] The first end 11 of the storage space 1 is open, and the open first end 11 is used to place materials that need to be aseptically transferred and then sealed to facilitate sterilization and aseptic transfer of the aseptic transfer bag 10. The sterilization method uses irradiation sterilization to prevent the sterile transfer bag 10 and the materials inside from being contaminated by the disinfectant. The sealing method of the first end 1 can be heat sealing, and the materials can be pre-filled flat dishes, etc.
[0034] The storage space 1 is made of flexible material and can be set into storage spaces 1 of different capacities and sizes according to the quantity, shape and size of the materials to be placed, so as to save materials and facilitate the retrieval and delivery of materials.
[0035] The second end 12 of the storage space 1 is sealed and closed by a passive valve cover 2, and the passive valve cover 2 has a fixing member 3 fixedly and sealedly connected to the storage space 1, and a sealing cover 4 that can be detachably connected to the fixing member 3. Optionally, the passive valve cover 2 can also be provided with a handle 5 connected to the fixing member 3, so that the passive valve cover 2 can be opened and closed. Figure 1 It can be seen from the embodiment that the handle 5 extends to the outside of the storage space 1, which is convenient for the user to grasp and facilitate operations such as clamping and transferring the sterile transfer bag 10, thereby speeding up the transfer process.
[0036] The fixing member 3 has an integrally formed connection ring 31 and a clamping portion 32. The fixing member 3 may be in a circular ring shape or a square shape to open the first end 11 of the storage space 1, so that the material placed in the storage space 1 can be placed in or taken out from the opening of the fixing member 3. As shown in the figure, the connection ring 31 is sealed with the storage space 1, and the sealing connection method is not limited to heat sealing, bonding, etc. The sealing of the fixing member 3 can ensure that the material in the storage space 1 is not contaminated and remains sterile, thereby ensuring the quality of the material.
[0037] The connection ring 31 can be closely attached to the outer wall of the port at the first end 11 of the storage space 1 and sealed, so as to reinforce the first end 11 of the storage space 1, reduce the external contact with the port at the first end 11, and prevent the port from being damaged. In an optional embodiment, the connection ring 31 can also be arranged close to the inner wall of the port at the first end 11, as long as it can be closely attached to the storage space 1.
[0038] The outer periphery of the clamping portion 32 is provided with a second groove 33, and the second groove 33 is used to clamp the active valve cover 6 (such as Figure 2 The inner periphery of the clamping portion 32 is provided with a first flange 34, and the outer periphery of the sealing cover 4 is provided with a corresponding first groove 35, the first groove 35 is suitable for clamping the first flange 34, and the first groove 35 is provided with a notch (not shown in the figure) corresponding to the first flange 34. By rotating the sterile transfer bag 10, the first flange 34 can be moved from the notch into and embedded in the first groove 35, so that the sealing cover 4 and the fixing member 3 are sealed and closed; the sterile transfer bag 10 can also be rotated to make the first flange 34 move out of the first groove 35, so that the sealing cover 4 is separated from the fixing member 3.
[0039] The handle 5 has a gripping portion 51 and a connecting portion 52. The gripping portion 51 and the connecting portion 52 can be integrally formed or separately fixedly connected. One end of the connecting portion 52 is connected to the connecting ring 31 of the fixing member 3, and the gripping portion 51 is connected to the other end of the connecting portion 52 and extends outwardly away from the storage space 1.
[0040] As shown in the figure, the connecting part 5 is an L-shaped rod, one end of which is fixedly connected to the connection between the connecting ring 31 and the clamping part 32, and the L-shaped rod extends to the outside of the storage space 1 and its bending area is bent toward the storage space 1, so that the hand-holding part 51 is located outside the storage space 1, and the end of the hand-holding part 51 is away from the storage space 1, thereby leaving space for the user to grasp.
[0041] The number of the hand-held parts 51 is not limited and can be two as in the embodiment shown in the figure, or multiple, so that the user can grasp it from various angles to facilitate the operation of taking, rotating, etc. of the sterile transfer bag 10.
[0042] According to the embodiment in the figure, the sealing cover 4 has a central groove 41, and the inner periphery of the central groove 41 is provided with a second flange 42, and the second flange 42 is used to be clamped on the active valve cover 6 (such as Figure 2 The second flange 42 can be engaged with the third flange 64 of the active valve cover 6 (as shown). Figure 3 As shown), the second flange 42 is provided with a notch (not shown in the figure), and by rotating the sterile transfer bag 10, the third flange 64 can be moved into and embedded in the central groove 41 to be fixed, or the third flange 64 can be moved out of the central groove 41.
[0043] It should be noted here that the notch of the second flange 42 is staggered with the notch of the first groove 35, that is, when the third flange 64 of the active valve cover 6 is snap-engaged with the central groove 41 of the sealing cover 4 of the passive valve cover 2, the first flange 34 of the passive valve cover 2 can be removed from the notch corresponding to the first groove 35, so that the active valve cover 6 can be linked to open the sealing cover 4 to complete the aseptic transfer of materials in the storage space 1.
[0044] In the embodiment as shown in the figure, optionally, the inner periphery of the fixing member 3 is a bevel cut 36, and the outer periphery of the sealing cover 4 is provided with a beveled surface 43 corresponding to the bevel cut 36, and the bevel cut 36 cooperates with the beveled surface 43 to facilitate the sealing closure or separation of the sealing cover 4 and the fixing member 3.
[0045] Figure 2 This is a schematic diagram of an active valve cover of an embodiment of a sterile transfer device of the utility model (a sterile isolation cabin is shown in the figure).
[0046] As can be seen from the figure, the active valve cover 6 is installed on the bulkhead 71 of the sterile isolation cabin 7, and the active valve cover 6 is opened to the inside of the sterile isolation cabin 7. The active valve cover 6 has a mounting member 61 and a coupling cover 62, and the active valve cover 6 is fixed to the bulkhead 71 through the mounting member 61.
[0047] Specifically, as shown in the figure, a third groove 63 is provided on the outer periphery of the mounting member 61 , and the bulkhead 71 can be snap-fitted and fixed to the third groove 63 , so that the active valve cover 6 is fixed to the bulkhead 71 of the sterile isolation cabin 7 .
[0048] The inner periphery of the mounting member 61 is provided with a fourth flange 69, which is used to be clamped to the fixing member 3 (such as the fixing member 3 of the passive valve cover 2 of the sterile transfer bag 10) Figure 3 As shown in the figure, the fourth flange 69 is an inclined surface, which can facilitate the access of the clamping portion 32 of the passive valve cover 2, so that the fourth flange 69 is clamped and fixed to the clamping portion 32 (as shown in the figure). Figure 3 as shown) and is not easy to fall off.
[0049] It can also be seen from the figure that the coupling cover 62 is provided with an intermediate boss 65 at one end away from the sterile isolation chamber 7, and the intermediate boss 65 is used to be clamped and fixed with the sealing cover 4 of the passive valve cover 2. Specifically, the peripheral edge of the intermediate boss 65 is provided with a third flange 64, and the third flange 64 is used to couple with the sealing cover 4 (such as Figure 3 In an optional embodiment, a handle 66 is provided at the other end of the coupling cover 62, and the handle 66 can facilitate users to open or close the active valve cover 6.
[0050] According to the embodiment in the figure, optionally, the active valve cover 6 also includes a hinge mechanism 67 and a locking mechanism 68, and the two ends of the hinge mechanism 67 are respectively connected to the coupling cover 62 and the mounting member 61. When the active valve cover 6 is opened, it can be rotated open around the hinge point between the hinge mechanism 67 and the mounting member 61. When placing or removing the product, the active valve cover 6 can be hung at the hinge point of the mounting member 61 to prevent the active valve cover 6 from being lost and contaminated.
[0051] It can be seen from the embodiment in the figure that the locking mechanism 68 includes a pressing portion 8 and an elastic handle 9 located on the periphery of the coupling cover 62. The elastic handle 9 can be pressed against and locked to lock the pressing portion 8, and the edge of the coupling cover 62 is pressed and sealed to lock the active valve cover 6 so that the active valve cover 6 is more sealed when closed. When opening, the elastic handle 9 is moved to release the lock between it and the pressing portion 8, so that the coupling cover 62 can be opened.
[0052] Figure 3 This is a schematic diagram of the coupling between the active valve cover and the passive valve cover of an embodiment of the aseptic transfer device of the utility model.
[0053] It can be clearly seen from the figure that the passive valve cover 2 of the sterile transfer bag 10 is coupled with the active valve cover 6. Specifically, the coupling cover 62 of the active valve cover 6 is coupled with the sealing cover 4 of the passive valve cover 2, and the mounting member 61 of the active valve cover 6 is coupled with the clamping portion 32 of the passive valve cover 2. Specifically, as shown in the figure, the third flange 64 of the coupling cover 62 and the second flange 42 of the sealing cover 4 are clamped with each other, and the fourth flange 69 of the mounting member 61 is clamped with the second groove 33 of the clamping portion 32, thereby the storage space 1 of the passive valve cover 2 is fixedly connected to the bulkhead 71 of the sterile isolation cabin 7 through the clamping portion 32 and the mounting member 61.
[0054] By rotating the sterile transfer bag 10, the sealing cover 4 of the passive valve cover 2 is separated from the clamping portion 32, and the clamping portion 32 of the passive valve cover 2 is clamped and fixed with the mounting member 61 of the active valve cover 6, and the sealing cover 4 of the passive valve cover 2 is clamped and fixed with the coupling cover 62 of the active valve cover 6. Thus, the coupling cover 62 and the sealing cover 4 can be opened together into the sterile transfer cabin 7, so that the material to be aseptically transferred can be taken out from the sterile transfer bag 10 and transferred to the sterile transfer cabin 7, or the material can be transferred from the sterile transfer cabin 7 to the sterile transfer bag 10.
[0055] Figure 4 This is a schematic diagram of an active valve cover and a passive valve cover being opened after being coupled in an embodiment of the aseptic transfer device of the utility model.
[0056] It can be clearly seen from the figure that the storage space 1 of the passive valve cover 2 is fixedly connected to the bulkhead 71 of the sterile isolation cabin 7 through the clamping portion 32 thereof and the mounting member 61 of the active valve cover 6, and the coupling cover 62 of the active valve cover 6 is coupled to the passive valve cover 2 and opened around the hinge mechanism 67 at the hinge point of the mounting member 61, so that materials that need to be aseptically transferred can be placed in or taken out between the sterile isolation cabin 7 and the sterile isolation bag 1.
[0057] The technical scope of the present invention is not limited to the contents in the above description. Those skilled in the art can make various deformations and modifications to the above implementation without departing from the technical idea of the present invention, and these deformations and modifications should all fall within the scope of the present invention.
Claims
1. A sterile transfer bag, characterized in that: The sterile transfer bag (10) has a flexible storage space (1), which is open at a first end (11) and sealed at a second end (12) by a passive valve cover (2). The passive valve cover (2) has a fixing member (3) sealedly connected to the storage space, and a sealing cover (4) that can be detached from the sealing connection with the fixing member (3).
2. The sterile transfer bag according to claim 1, characterized in that: The fixing member (3) comprises a connecting ring (31) fixedly connected to the storage space (1) and a clamping portion (32) connected to the connecting ring (31); a first flange (34) is provided on the inner periphery of the clamping portion (32); The outer periphery of the sealing cover (4) is provided with a first groove (35), the first groove (35) being suitable for snapping into the first flange (34), and the first groove (35) is also provided with a notch corresponding to the first flange (34), the first flange (34) being able to move in or out of the notch, thereby enabling the sealing cover (4) to be sealed closed or detached from the fixing member (3).
3. The sterile transfer bag according to claim 2, characterized in that: The first end (11) of the storage space (1) is heat-sealed or adhesively connected to the connecting ring (31) of the fixing member (3).
4. The sterile transfer bag according to claim 2, characterized in that: The fixing member (3) is connected to a handle (5), the handle (5) comprising a hand-holding portion (51) and a connecting portion (52), one end of the connecting portion (52) being connected to the connecting ring (31), and the hand-holding portion (51) being connected to the other end of the connecting portion (52).
5. The sterile transfer bag according to claim 4, characterized in that: The connecting portion (52) is an L-shaped rod, one end of the L-shaped rod is fixedly connected to the connection between the connecting ring (31) and the clamping portion (32), the other end of the L-shaped rod is connected to the hand-held portion (51), and the end of the hand-held portion (51) extends away from the storage space (1).
6. The sterile transfer bag according to claim 2, characterized in that: The outer periphery of the clamping portion (32) is provided with a second groove (33), the sealing cover (4) has a central groove (41), and the inner periphery of the central groove (41) is provided with a second flange (42).
7. The sterile transfer bag according to claim 1, characterized in that: The inner periphery of the fixing member (3) is an oblique cut (36), and the outer periphery of the sealing cover (4) is provided with an oblique cut surface (43) corresponding to the oblique cut (36) suitable for sealing and covering with the fixing member (3).
8. A sterile transfer device, characterized in that: The aseptic transfer device comprises a sterile transfer bag (10) as described in any one of claims 1 to 7, and an active valve cover (6), wherein the first end (11) of the sterile transfer bag (10) is sealed and closed, and the active valve cover (6) is used to be installed on the bulkhead (71) of the sterile isolation cabin (7), and the active valve cover (6) can be coupled with the passive valve cover (2) and enable the sealing cover (4) of the passive valve cover (2) to be separated from the fixing member (3) and opened.
9. The aseptic transfer device according to claim 8, characterized in that: The active valve cover (6) comprises a mounting member (61) fixed to the bulkhead (71) of the sterile isolation cabin (7) and a coupling cover (62) detachably connected to the mounting member (61); A third groove (63) is provided on the outer periphery of the mounting member (61), and the third groove (63) is used to clamp the bulkhead (71) of the isolation cabin; a fourth flange (69) is provided on the inner periphery of the mounting member (61), and the fourth flange (69) is used to clamp the fixing member (3) of the passive valve cover (2) of the sterile transfer bag; The coupling cover (62) is provided with an intermediate boss (65), and a third flange (64) is provided on the periphery of the intermediate boss (65), wherein the third flange (64) is used to be coupled to the sealing cover (4) of the passive valve cover (2).
10. The sterile transfer device according to claim 9, characterized in that: The active valve cover (6) further comprises a hinge mechanism (67) and a locking mechanism (68), wherein the hinge mechanism (67) is used to hinge the coupling cover (62) to the mounting member (61); the locking mechanism (68) comprises a pressing portion (8) and an elastic handle (9) located at the periphery of the coupling cover (62), wherein the elastic handle (9) is used to press or release the pressing portion (8).