Novel constant-temperature gene recombination kit
By designing a constant temperature gene recombinant kit containing a semiconductor refrigeration sheet and a temperature sensor, the problem of reagent tubes not being stored at low temperature in the prior art is solved, and the stable storage and transportation of reagents are achieved.
Patent Information
- Application Number
- CN202421016253.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-11
- Publication Date
- 2025-02-25
- Estimated Expiration
- 2034-05-11
AI Technical Summary
The existing gene recombinant kits cannot store the reagent tubes at low temperature, resulting in the reagent being easily inactivated for a long time, and the existing technology has not effectively solved this problem.
A new constant temperature gene recombinant kit has been designed, including a heat dissipation base, a kit and a top cover. The kit is equipped with a semiconductor refrigeration sheet and a temperature sensor. The temperature can be adjusted through the control panel to ensure that the reagent is stored under constant temperature conditions.
Through the design of this kit, the reagent tube is stored under constant temperature conditions, avoiding the problem of reagent deactivation caused by temperature changes, and ensuring the stability and storage effect of the reagent.
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Abstract
Description
Technical Field
[0001] The utility model relates to the field of test kits, and more specifically, to a novel constant-temperature gene recombination test kit. Background Art
[0002] A test kit generally refers to a box that contains chemical reagents such as drug residues. It is used to contain chemical reagents for detecting chemical components, drug residues, and virus types. It is generally used by hospitals and pharmaceutical companies. Test kits are usually used in the process of genetic recombination research and development experiments;
[0003] After searching, the existing patent (Announcement No.: CN218344068U) discloses a novel gene recombination kit, including an inner box, the inner side wall of the inner box is provided with a slide groove, and the inner wall of the slide groove is movably connected with a slider, one side of the slider is fixedly connected with a placement frame, the top of the placement frame is provided with a tube groove, the inner wall of the tube groove is fixedly connected with a first return spring, and one end of the first return spring is fixedly connected with a first clamping plate. The novel gene recombination kit, by providing a placement frame, a first clamping plate, a first return spring, a tube groove, a second clamping plate, a rubber pad, a second return spring and a reagent tube, can clamp and limit the position of the reagent tube when the reagent tube is stored through the kit, thereby reducing the shaking and trembling of the reagent tube when carrying the kit, thereby improving the stability and placement effect of the reagent tube, and further meeting people's demand for the use of the gene recombination kit.
[0004] Most existing gene recombination reagents generally need to be transported with ice packs and stored at low temperatures. Existing gene recombination kits have a single function, which is to store reagent tubes. Reagent tubes cannot be stored at low temperatures, and reagents are prone to inactivation when stored for a long time. At the same time, the above-cited patent documents do not propose relevant solutions to solve the above problems.
[0005] Therefore, a novel thermostatic gene recombination kit is proposed to solve the above problems. Utility Model Content
[0006] In order to overcome the above-mentioned defects of the prior art, the embodiments of the present invention provide a novel thermostatic gene recombination kit to solve the problems raised in the above-mentioned background technology.
[0007] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a novel constant temperature gene recombination kit, comprising a heat dissipation base, a kit is installed on the top of the heat dissipation base, and a control panel is installed at one end of the heat dissipation base, a semiconductor cooling sheet is arranged at the bottom of the inside of the kit, and a temperature sensor is installed on the inner wall of the kit, a top cover is hinged on the top of the kit, and a handle is hinged at the middle position of the top of the top cover;
[0008] A mounting plate is arranged at the top of the reagent box, and a fastening assembly is installed at the top of one end of the reagent box close to the control panel. Slots are evenly arranged in the mounting plate, and limiting clamps are evenly arranged on the inner sides of the slots.
[0009] Preferably, the test kit comprises an outer shell, a heat-insulating layer and a waterproof layer, the inner side wall of the outer shell is provided with the heat-insulating layer, and the inner wall of the heat-insulating layer is provided with the waterproof layer.
[0010] Preferably, a water inlet pipe is provided on the top of one side of the reagent box, and a water outlet pipe is provided on the reagent box below the water inlet pipe, and an observation window is provided on one side of the reagent box close to the water inlet pipe.
[0011] Preferably, the fastening assembly includes an articulated seat, a connecting rod, a return spring, a clamping piece and a fastening screw, and the articulated seat is connected to the side wall of the test kit by a bolt, a connecting rod is hinged on the articulated seat, and a clamping piece is sleeved on the end of the connecting rod away from the articulated seat, a return spring is wound around the outside of the connecting rod between the articulated seat and the clamping piece, and a fastening screw is rotatably installed on the end of the clamping piece away from the articulated seat.
[0012] Preferably, a downwardly recessed limiting groove is provided at a position of the top cover near the fastening assembly, and a pressing groove matching the shape of the limiting groove is provided at a position of the pressing member near the limiting groove.
[0013] Preferably, a sealing rubber ring is provided at the edge of the bottom of the top cover, and the edge of the top of the reagent box is recessed downward to form a sealing groove matched with the sealing rubber ring.
[0014] Preferably, the tops of the limiting clamps are all designed to be arc-shaped and outwardly expanded, and the limiting clamps are elastically connected to the inner wall of the slot via a spring.
[0015] Preferably, the connecting rod is designed as a square tube, and a through groove matching the shape of the connecting rod is opened inside the clamping piece, a threaded groove matching the fastening screw is opened inside the connecting rod, and a wristband is fixed to the end of the fastening screw away from the connecting rod.
[0016] Technical effects and advantages of the utility model:
[0017] Compared with the prior art, the novel constant temperature gene recombination reagent kit is provided with a reagent kit and a top cover, which can form a closed storage space, wherein the reagent kit part includes an outer shell, a thermal insulation layer and a waterproof layer, and the thermal insulation effect is better. When the reagent tube is stored in the reagent kit, it is not easily affected by the external temperature. At the same time, ice water can be added to the reagent kit for an ice water bath. The temperature sensor can detect the temperature in the reagent kit. When it is higher than the set value, the semiconductor refrigeration plate works to cool the water, so that the gene recombination reagent is not easy to deteriorate during storage and transportation. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] Figure 1 It is a schematic diagram of the top cover closing structure of the utility model.
[0019] Figure 2 It is a schematic diagram of the top cover opening structure of the utility model.
[0020] Figure 3 It is a schematic diagram of the cutaway structure of the test kit of the utility model.
[0021] Figure 4 This is a schematic diagram of the structure of the mounting plate of the utility model.
[0022] Figure 5 It is a schematic diagram of the disassembled structure of the fastening assembly of the utility model.
[0023] The accompanying drawings are marked as follows: 1. heat dissipation base; 2. test kit; 201. sealing groove; 202. outer shell; 203. insulation layer; 204. waterproof layer; 3. fastening assembly; 4. top cover; 401. limit groove; 402. sealing rubber ring; 5. handle; 6. observation window; 7. water outlet pipe; 8. water inlet pipe; 9. control panel; 10. hinge seat; 11. mounting plate; 12. semiconductor refrigeration plate; 13. temperature sensor; 14. limit clamp; 15. slot; 16. connecting rod; 1601. threaded groove; 17. reset spring; 18. clamping piece; 1801. clamping groove; 1802. through groove; 19. fastening screw; 20. wristband. DETAILED DESCRIPTION
[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model. Embodiment 1
[0025] As attached Figure 1 A novel constant temperature gene recombination kit is shown, comprising a heat dissipation base 1, a reagent kit 2 is installed on the top of the heat dissipation base 1, and a control panel 9 is installed at one end of the heat dissipation base 1, a semiconductor cooling sheet 12 is arranged at the bottom of the inside of the reagent kit 2, and a temperature sensor 13 is installed on the inner wall of the reagent kit 2, a top cover 4 is hinged on the top of the reagent kit 2, and a handle 5 is hinged at the middle position of the top of the top cover 4;
[0026] A mounting plate 11 is disposed at the top of the reagent box 2 , and a fastening assembly 3 is installed at the top of the reagent box 2 near the control panel 9 . Slots 15 are evenly arranged in the mounting plate 11 , and limiting clamps 14 are evenly arranged on the inner sides of the slots 15 .
[0027] Among them: the reagent box 2 and the top cover 4 can form a closed storage space. Ice water is added to the reagent box 2 to perform an ice water bath on the genetic recombination reagent tube. The temperature sensor 13 can detect the water temperature in the reagent box 2. When it is higher than the set value, the semiconductor refrigeration plate 12 works to cool the water, so that the genetic recombination reagent is not easily deteriorated during storage and transportation. Embodiment 2
[0028] Based on the first embodiment, the solution in the first embodiment is further detailed in combination with the following specific working methods. Figures 1 to 5 As shown, see the following description for details:
[0029] As a preferred embodiment, the test kit 2 includes an outer shell 202, an insulation layer 203 and a waterproof layer 204. The inner wall of the outer shell 202 is installed with the insulation layer 203, and the inner wall of the insulation layer 203 is provided with the waterproof layer 204; further, the outer shell 202, the insulation layer 203 and the waterproof layer 204 are designed so that the thermal insulation effect of the test kit 2 is better, and when the reagent tube is stored in the test kit 2, it is not easily affected by the external temperature.
[0030] As a preferred embodiment, a water inlet pipe 8 is provided on the top of one side of the reagent box 2, and a water outlet pipe 7 is provided on the reagent box 2 below the water inlet pipe 8, and an observation window 6 is provided on the side of the reagent box 2 close to the water inlet pipe 8; further, the design of the water inlet pipe 8 and the water outlet pipe 7 makes it more convenient to add and discharge ice water in the reagent box 2, and the design is more reasonable.
[0031] As a preferred embodiment, the fastening assembly 3 includes an articulated seat 10, a connecting rod 16, a return spring 17, a clamping piece 18 and a fastening screw 19, and the articulated seat 10 is connected to the side wall of the reagent box 2 by bolts, the articulated seat 10 is hinged with a connecting rod 16, and the end of the connecting rod 16 away from the articulated seat 10 is sleeved with a clamping piece 18, a return spring 17 is wound around the outer side of the connecting rod 16 between the articulated seat 10 and the clamping piece 18, and the end of the clamping piece 18 away from the articulated seat 10 is rotatably installed with a fastening screw 19; further, when in use, it is only necessary to tighten the fastening screw 19 to move the clamping piece 18 down and press the top cover 4, which is very convenient to operate, and when opening the cover, it is only necessary to slightly loosen the fastening screw 19, and the clamping piece 18 can move up a distance under the action of the return spring 17, at this time, the connecting rod 16 can be turned from a vertical state to a horizontal state, so that the clamping piece 18 is separated from the top cover 4, and the top cover 4 is opened and closed very conveniently, thereby improving the convenience of using the device.
[0032] As a preferred embodiment, a downwardly recessed limiting groove 401 is provided at the top of the top cover 4 near the fastening assembly 3, and a clamping groove 1801 matching its shape is provided at the position of the clamping member 18 near the limiting groove 401; further, the clamping groove 1801 and the limiting groove 401 match each other, so that the clamping member 18 has a better fixing effect on the top cover 4.
[0033] As a preferred embodiment, a sealing rubber ring 402 is provided at the edge of the bottom of the top cover 4, and the edge of the top of the reagent box 2 is recessed downward to form a sealing groove 201 that matches the sealing rubber ring 402; further, when the top cover 4 is closed, the sealing rubber ring 402 is embedded in the sealing groove 201, so that the sealing performance of the device is better and the internal liquid is not easy to leak.
[0034] As a preferred embodiment, the top of the limiting clamp 14 is designed to be arc-shaped and outwardly expanded, and the limiting clamp 14 is elastically connected to the inner wall of the slot 15 through a spring; further, the arc-shaped and outwardly expanded design makes it easier to insert the reagent tube between the limiting clamps 14, and the storage of the reagent tube is more convenient. The elastic connection design allows the limiting clamp 14 to clamp the reagent tube under the action of the spring force, which is convenient for storing reagent tubes of different specifications and has better applicability.
[0035] As a preferred embodiment, the connecting rod 16 is designed as a square tube, and the interior of the clamping piece 18 is provided with a through groove 1802 that matches the shape of the connecting rod 16, the interior of the connecting rod 16 is provided with a threaded groove 1601 that matches the fastening screw 19, and a wristband 20 is fixed to the end of the fastening screw 19 away from the connecting rod 16; further, the square tube design prevents relative rotation between the clamping piece 18 and the connecting rod 16, so the clamping groove 1801 of the clamping piece 18 can always face the limiting groove 401 of the top cover 4, is not prone to deflection, and has a better clamping effect.
[0036] The working process of the utility model is as follows:
[0037] When in use, turn on the power, first open the top cover 4, insert the reagent tube to be stored into the slot 15, the limiting clamp 14 can clamp the reagent tube under the action of the spring elastic force, cover the top cover 4, and use the fastening component 3 to limit the top cover 4, and then pass ice water into the reagent box 2 through the water inlet pipe 8 to give the reagent tube an ice water bath. The temperature sensor 13 can detect the water temperature in the reagent box 2. When it is higher than the set value, the semiconductor refrigeration plate 12 works to cool the water. When the reagent tube needs to be taken, just slightly loosen the fastening screw 19, and the clamping piece 18 can move up a distance under the action of the reset spring 17. At this time, the connecting rod 16 can be turned from a vertical state to a horizontal state, so that the clamping piece 18 is separated from the top cover 4, making the top cover 4 easy to open.
[0038] Finally: The above are only preferred embodiments of the present utility model and are not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present utility model should be included in the protection scope of the present utility model.
Claims
1. A novel constant temperature gene recombination kit, comprising a heat dissipation base (1), characterized in that: A test kit (2) is installed on the top of the heat dissipation base (1), and a control panel (9) is installed on one end of the heat dissipation base (1); a semiconductor cooling plate (12) is arranged at the bottom of the test kit (2), and a temperature sensor (13) is installed on the inner wall of the test kit (2); a top cover (4) is hingedly connected to the top of the test kit (2), and a handle (5) is hingedly connected at the middle position of the top of the top cover (4); A mounting plate (11) is arranged at the top of the reagent box (2), and a fastening assembly (3) is installed at the top of one end of the reagent box (2) close to the control panel (9). Slots (15) are evenly arranged in the mounting plate (11), and limiting clamps (14) are evenly arranged on the inner sides of the slots (15).
2. A novel thermostatic gene recombination kit according to claim 1, characterized in that: The test kit (2) comprises an outer shell (202), a heat-insulating layer (203) and a waterproof layer (204); the inner side wall of the outer shell (202) is provided with the heat-insulating layer (203), and the inner wall of the heat-insulating layer (203) is provided with the waterproof layer (204).
3. A novel thermostatic gene recombination kit according to claim 1, characterized in that: A water inlet pipe (8) is provided at the top of one side of the reagent box (2), and a water outlet pipe (7) is provided on the reagent box (2) below the water inlet pipe (8). An observation window (6) is provided on one side of the reagent box (2) close to the water inlet pipe (8).
4. A novel thermostatic gene recombination kit according to claim 1, characterized in that: The fastening assembly (3) comprises an articulated seat (10), a connecting rod (16), a return spring (17), a pressing piece (18) and a fastening screw (19), and the articulated seat (10) is connected to the side wall of the reagent box (2) by means of bolts, the articulated seat (10) is hinged with a connecting rod (16), and the end of the connecting rod (16) away from the articulated seat (10) is sleeved with the pressing piece (18), the outer side of the connecting rod (16) between the articulated seat (10) and the pressing piece (18) is wound with a return spring (17), and the end of the pressing piece (18) away from the articulated seat (10) is rotatably mounted with the fastening screw (19).
5. A novel thermostatic gene recombination kit according to claim 4, characterized in that: A downwardly recessed limiting groove (401) is provided at a position of the top of the top cover (4) close to the fastening assembly (3), and a pressing groove (1801) matching the shape of the limiting groove (401) is provided at a position of the pressing member (18) close to the limiting groove (401).
6. A novel thermostatic gene recombination kit according to claim 1, characterized in that: A sealing rubber ring (402) is provided at the edge of the bottom of the top cover (4), and the edge of the top of the reagent box (2) is recessed downward to form a sealing groove (201) that matches the sealing rubber ring (402).
7. A novel thermostatic gene recombination kit according to claim 1, characterized in that: The tops of the limiting clamps (14) are all designed to be arc-shaped and outwardly expanded, and the limiting clamps (14) are elastically connected to the inner wall of the slot (15) via a spring.
8. A novel thermostatic gene recombination kit according to claim 4, characterized in that: The connecting rod (16) is designed as a square tube, and a through groove (1802) matching the shape of the connecting rod (16) is provided inside the pressing piece (18), a thread groove (1601) matching the fastening screw (19) is provided inside the connecting rod (16), and a hand ring (20) is fixed to the end of the fastening screw (19) away from the connecting rod (16).
Citation Information
Patent Citations
Novel gene recombination kit
CN218344068U