Sampler for intestinal flora of experimental animal

By designing a confined space experimental animal intestinal microbiota sampler, using the combination of elastic sleeve and rotary sampling swab, the problem of exposure to air when mixed with liquid in the prior art is solved, and the accuracy of the detection results is improved.

CN222524546UActive Publication Date: 2025-02-25SHENZHEN CENTER FOR DISEASE CONTROL AND PREVENTION (SHENZHEN HEALTH INSPECTION CENTER SHENZHEN INSTITUTE OF PREVENTIVE MEDICINE)
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Patent Information

Application Number
CN202420899419.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-28
Publication Date
2025-02-25
Estimated Expiration
2034-04-28

AI Technical Summary

Technical Problem

Existing experimental animal intestinal microbiota samplers are exposed to air during the mixing of the sample with the liquid, causing external bacteria to adhere to the feces, affecting the detection results.

Method used

A sampler for intestinal flora of experimental animals was designed. The sampling tube was equipped with a collection assembly and a marking assembly. The collection assembly included an elastic sleeve and a rotating sampling swab to ensure that the sample was in a confined space when mixed with the liquid.

Benefits of technology

Through the design of the confined space, external bacteria are avoided from adhering to animal feces, improving the accuracy and reliability of the test results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an experimental animal intestinal flora sampler which comprises a sampling pipe, an external thread pipe is fixedly arranged at the top of the sampling pipe, an internal thread cover is arranged on the surface of the external thread pipe in a threaded mode, a connecting hole is formed in the top of the internal thread cover in a penetrating mode, and a mounting column is arranged on the upper side wall of the internal thread cover in a lap joint mode. And a fixing stud is fixedly arranged at the top of the mounting column, and the fixing stud and the connecting hole are arranged in a lap joint mode. The knob drives the fixed stud to rotate through the threaded hole, and the fixed stud drives the mounting column to rotate, so that the mounting column drives the sampling cotton swab to rotate through the mounting hole and the elastic sleeve, liquid in the sampling pipe and excrement on the sampling cotton swab are mixed, and a collected sample and the liquid are in a closed space when being mixed; the situation that bacteria in the external environment are attached to the animal waste due to the fact that the animal waste is mixed with liquid and exposed in the external environment after collection is avoided, and the situation that external infectious microbes are attached to the animal waste and affect a detection structure is avoided.
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Description

Technical Field

[0001] The utility model relates to the technical field of laboratory animal intestinal inspection, in particular to a sampler for intestinal flora of laboratory animals. Background Art

[0002] Intestinal flora refers to the large number of bacteria that exist in the intestines of animals. This group of bacteria relies on the intestines of animals to live and helps the host complete a variety of physiological and biochemical functions. The intestine is not only an important place for digestion and absorption in animals, but also the largest immune organ. It plays an extremely important role in maintaining normal immune defense functions. Normal bacteria in the intestines of animals, such as bifidobacteria and lactobacilli, can synthesize a variety of vitamins necessary for human growth and development.

[0003] The detection of intestinal flora can reflect the digestive capacity and health risks of the animal's intestine. Samples are usually collected from animal feces. In order to reduce the influence of various factors in the intermediate links, sampling is preferably performed from the anus. A cotton swab is usually dipped in animal feces, and the cotton swab dipped in animal feces is placed in a sampling tube and contacted with the liquid in the sampling tube. The cotton swab is then stirred in the liquid for thirty seconds. During the process of mixing the sample with the liquid, the sampler is exposed to the air, which causes the sampled feces to be in contact with the air for too long, which can easily cause bacteria in the external environment to adhere to the collected animal feces, thereby affecting the test results. Therefore, a sampler for intestinal flora of experimental animals is proposed. Utility Model Content

[0004] In view of the deficiencies of the prior art, the utility model provides a sampler for intestinal flora of experimental animals, which is used to solve the problems raised in the above-mentioned background technology.

[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0006] A sampler for intestinal flora of experimental animals comprises a sampling tube, an externally threaded tube is fixedly provided on the top of the sampling tube, an internally threaded cover is threadedly provided on the surface of the externally threaded tube, a connecting hole is penetrated through the top of the internally threaded cover, a mounting column is overlapped on the upper side wall of the internally threaded cover, a fixing stud is fixedly provided on the top of the mounting column, the fixing stud is overlapped with the connecting hole, a knob is overlapped on the top of the internally threaded cover, a threaded hole is opened at the bottom of the knob, the threaded hole is threadedly connected with the fixing stud, a collection component is provided on the mounting column, and an identification component is provided on the surface of the sampling tube.

[0007] Preferably, the collection component includes a mounting hole, which is opened at the bottom of the mounting column and is recessed upward in the vertical direction. An elastic sleeve is fixedly arranged inside the mounting hole, and a sampling cotton swab is overlapped inside the elastic sleeve.

[0008] Preferably, the identification component comprises an adhesive layer, the adhesive layer is bonded to the surface of the sampling tube, and a label paper is bonded to a side of the adhesive layer away from the sampling tube.

[0009] Preferably, scale lines are provided on the front side of the sampling tube, and the readings of the scale lines increase from bottom to top.

[0010] Preferably, the sampling tube is of a circular structure, a containing cavity is provided inside the sampling tube, and the bottom of the containing cavity is semicircular, and the sampling tube is colorless and transparent.

[0011] Preferably, the elastic sleeve has a circular transverse cross-section and is made of elastic rubber.

[0012] Compared with the prior art, the beneficial effects of the utility model are as follows: for the sampler of intestinal flora of experimental animals, after the sampling cotton swab collects animal feces, the sampling cotton swab is placed in the sampling tube, and the internal threaded cover is tightened on the external threaded tube, and the knob drives the fixed stud to rotate through the threaded hole, and the fixed stud drives the mounting column to rotate, so that the mounting column drives the sampling cotton swab to rotate through the mounting hole and the elastic sleeve, thereby mixing the liquid in the sampling tube with the feces on the sampling cotton swab, so that the collected sample is in a closed space when mixed with the liquid, avoiding the situation where the sample is mixed with the liquid after collection and exposed to the external environment, causing the bacteria in the external environment to adhere to the animal feces, and avoiding the external bacteria adhering to the animal feces to affect the detection structure. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is the structural survey drawing of the utility model;

[0014] Figure 2 It is a schematic diagram of the structure sampler of the utility model;

[0015] Figure 3 It is a schematic diagram of the local structure of the utility model;

[0016] Figure 4 This is a schematic diagram of the longitudinal section structure of the utility model;

[0017] Figure 5 for Figure 4 A magnified view of the structure at the A punch.

[0018] In the figure: 1. Sampling tube; 2. Externally threaded tube; 3. Internally threaded cap; 4. Connecting hole; 5. Mounting column; 6. Mounting hole; 7. Sampling cotton swab; 8. Fixing stud; 9. Knob; 10. Threaded hole; 11. Scale line; 12. Adhesive layer; 13. Label paper; 14. Elastic sleeve. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0020] Reference Figure 1-5 A sampler for intestinal flora of experimental animals comprises a sampling tube 1, an externally threaded tube 2 is fixedly arranged on the top of the sampling tube 1, an internally threaded cover 3 is threadedly arranged on the surface of the externally threaded tube 2, a connecting hole 4 is penetrated through the top of the internally threaded cover 3, a mounting column 5 is overlapped on the upper side wall of the internally threaded cover 3, a fixing stud 8 is fixedly arranged on the top of the mounting column 5, the fixing stud 8 is overlapped with the connecting hole 4, a knob 9 is overlapped on the top of the internally threaded cover 3, a threaded hole 10 is opened at the bottom of the knob 9, the threaded hole 10 is threadedly connected with the fixing stud 8, a collecting component is arranged on the mounting column 5, and the collecting component The mounting hole 6 comprises a mounting hole 6, which is arranged at the bottom of the mounting column 5, and is concave upward in the vertical direction. An elastic sleeve 14 is fixedly arranged inside the mounting hole 6, and the elastic sleeve 14 is circular in transverse cross section. The elastic sleeve 14 is made of elastic rubber. The elastic sleeve 14 made of elastic rubber makes it difficult for the sampling cotton swab 7 to fall out of the mounting hole 6 after the sampling cotton swab 7 is inserted into the mounting hole 6. The sampling cotton swab 7 is overlapped inside the elastic sleeve 14. The sampling tube 1 is a circular structure, and a holding cavity is arranged inside the sampling tube 1, and the bottom of the holding cavity is semicircular. The sampling tube 1 is colorless and transparent. The over-containing cavity is convenient for containing liquids and for placing the sampling cotton swab 7 inside the sampling tube 1. The colorless and transparent sampling tube 1 is convenient for checking the mixing status inside the sampling tube 1. The sampling cotton swab 7 is inserted into the mounting hole 6 so that the sampling cotton swab 7 squeezes the elastic sleeve 14 so that the elastic sleeve 14 fixes the sampling cotton swab 7 in the mounting hole 6, thereby facilitating the replacement of the sampling cotton swab 7. When an operation error occurs during the collection process, the sampling cotton swab 7 can be quickly replaced. After the sampling cotton swab 7 collects animal feces, the sampling cotton swab 7 is placed in the sampling tube 1. 1, and tighten the internal thread cover 3 on the external thread tube 2, the knob 9 drives the fixing stud 8 to rotate through the threaded hole 10, and the fixing stud 8 drives the mounting column 5 to rotate, so that the mounting column 5 drives the sampling cotton swab 7 to rotate through the mounting hole 6 and the elastic sleeve 14, thereby mixing the liquid in the sampling tube 1 with the feces on the sampling cotton swab 7, so that the collected sample is in a closed space when mixed with the liquid, avoiding the situation that the sample is mixed with the liquid after collection and exposed to the external environment, causing the bacteria in the external environment to adhere to the animal feces, and avoiding the external bacteria adhering to the animal feces to affect the detection structure.

[0021] Specifically, an identification component is provided on the surface of the sampling tube 1, and the identification component includes an adhesive layer 12. The adhesive layer 12 is bonded to the surface of the sampling tube 1. A label paper 13 is bonded to the side of the adhesive layer 12 away from the sampling tube 1. The label paper 13 is bonded to the surface of the sampling tube 1 through the adhesive layer 12, so that the sampling personnel can mark the sampling tube 1 easily. The marking makes it difficult to take the sampling tube 1 by mistake later.

[0022] Specifically, a scale line 11 is set on the front side of the sampling tube 1, and the reading of the scale line 11 increases from bottom to top. The setting of the scale line 11 facilitates the measurement of the liquid added to the sampling tube 1, avoiding the situation where too much or too little liquid is added to the sampling tube 1, and avoiding the influence of over-dilution or under-dilution on the detection result.

[0023] During use: rotate the internal threaded cover 3 to remove the internal threaded cover 3 from the surface of the external threaded tube 2, so that the internal threaded cover 3 drives the knob 9 to move upward, and the knob 9 drives the fixing stud 8 to move upward through the threaded hole 10, so that the fixing stud 8 drives the mounting column 5 to move upward, so that the mounting column 5 takes out the sampling cotton swab 7 from the sampling tube 1 through the mounting hole 6 and the elastic sleeve 14, and collects animal feces through the sampling cotton swab 7. After the collection is completed, the sampling cotton swab 7 is placed in the sampling tube 1, and the internal threaded cover 3 is screwed into the surface of the external threaded tube 2, and the knob 9 is rotated so that the knob 9 drives the fixing stud 8 to rotate through the threaded hole 10, and drives the mounting column 5 to rotate through the fixing stud 8, so that the mounting column 5 drives the sampling cotton swab 7 to rotate through the mounting hole 6 and the elastic sleeve 14, so that the animal feces collected on the sampling cotton swab 7 is repeatedly mixed with the liquid in the sampling tube 1.

[0024] To sum up, in the sampler for intestinal flora of experimental animals, after the sampling cotton swab 7 collects animal feces, the sampling cotton swab 7 is placed in the sampling tube 1, and the internal threaded cover 3 is tightened on the external threaded tube 2, and the knob 9 drives the fixing stud 8 to rotate through the threaded hole 10, and the fixing stud 8 drives the mounting column 5 to rotate, so that the mounting column 5 drives the sampling cotton swab 7 to rotate through the mounting hole 6 and the elastic sleeve 14, thereby mixing the liquid in the sampling tube 1 with the feces on the sampling cotton swab 7, so that the collected sample is in a closed space when mixed with the liquid, avoiding the situation where the sample is mixed with the liquid after collection and exposed to the external environment, causing the bacteria in the external environment to adhere to the animal feces, and avoiding the external bacteria adhering to the animal feces to affect the detection structure, which is used to solve the problems raised in the above-mentioned background technology.

[0025] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0026] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A sampler for intestinal flora of experimental animals, comprising a sampling tube (1), characterized in that: An externally threaded tube (2) is fixedly arranged on the top of the sampling tube (1), an internally threaded cover (3) is threadedly arranged on the surface of the externally threaded tube (2), a connecting hole (4) is penetrated through the top of the internally threaded cover (3), a mounting column (5) is overlapped on the upper side wall of the internally threaded cover (3), a fixing stud (8) is fixedly arranged on the top of the mounting column (5), the fixing stud (8) is overlapped with the connecting hole (4), a knob (9) is overlapped on the top of the internally threaded cover (3), a threaded hole (10) is opened at the bottom of the knob (9), the threaded hole (10) is threadedly connected with the fixing stud (8), a collection component is arranged on the mounting column (5), and an identification component is arranged on the surface of the sampling tube (1).

2. A sampler for intestinal flora of experimental animals according to claim 1, characterized in that: The collection component comprises a mounting hole (6), the mounting hole (6) being formed at the bottom of the mounting column (5), the mounting hole (6) being recessed upward in the vertical direction, an elastic sleeve (14) being fixedly arranged inside the mounting hole (6), and a sampling cotton swab (7) being overlapped and arranged inside the elastic sleeve (14).

3. The sampler for intestinal flora of experimental animals according to claim 1, characterized in that: The identification component comprises an adhesive layer (12), the adhesive layer (12) being bonded to the surface of the sampling tube (1), and a label paper (13) being bonded to a side of the adhesive layer (12) away from the sampling tube (1).

4. The sampler for intestinal flora of experimental animals according to claim 1, characterized in that: The sampling tube (1) is provided with scale lines (11) on the front side, and the readings of the scale lines (11) increase from bottom to top.

5. The sampler for intestinal flora of experimental animals according to claim 1, characterized in that: The sampling tube (1) is of a circular structure, a containing cavity is provided inside the sampling tube (1), and the bottom of the containing cavity is semicircular, and the sampling tube (1) is colorless and transparent.

6. A sampler for intestinal flora of experimental animals according to claim 2, characterized in that: The elastic sleeve (14) has a circular transverse cross-section, and the elastic sleeve (14) is made of elastic rubber.