Cryoablation system

Abstract

The embodiment of the utility model relates to the technical field of cryotherapy, in particular to a cryoablation system which comprises a freezing module, a rewarming module and an ablation module. The freezing module and the rewarming module are respectively connected and communicated with the ablation module, the freezing module conveys a cold working medium into the ablation module for cooling ablation consumables in the ablation module, and the rewarming module conveys a hot working medium into the ablation module for heating the ablation consumables in the ablation module. The liquid nitrogen conveying device has the advantages that heat exchange between liquid nitrogen and air is achieved through the heat transfer pipe, so that nitrogen is generated and used for providing pressure for conveying the liquid nitrogen, arrangement of an electrical structure for heating or pressurizing is reduced, equipment cost is reduced, meanwhile, use of electrical components is reduced, stability of equipment is improved, and the possibility of faults is reduced.

Description

Technical Field

[0001] The embodiment of the utility model relates to the technical field of low-temperature cryotherapy, and in particular to a cryoablation system. Background Art

[0002] Cryoablation is a surgical medical technology that uses freezing to eliminate target tissue. As a minimally invasive targeted surgery, cryoablation is characterized by small trauma, few toxic side effects, and definite efficacy. It also has the advantages of clear boundaries of the ablation ice ball, participation in activating the body's tumor immune function, no damage to large blood vessels, and no obvious pain. It is widely used in the treatment of various tumors, emphysema and other diseases.

[0003] The principle is to use low-temperature equipment to make the target tissue undergo a process of cooling, freezing, and thawing, thereby causing irreversible damage or necrosis to the cells.

[0004] Existing cryoablation systems usually use nitrogen as the cryofluid and assist in the delivery of the cryofluid by setting up electrical structures such as heating devices or boosting devices. However, this method has the disadvantages of high equipment cost, poor stability, and high failure rate due to its complex structure. Utility Model Content

[0005] The embodiment of the utility model provides a cryoablation system, comprising: a freezing module, a rewarming module and an ablation module;

[0006] The freezing module and the rewarming module are respectively connected and communicated with the ablation module, the freezing module delivers cold working fluid to the ablation module for cooling the ablation consumables in the ablation module, and the rewarming module delivers hot working fluid to the ablation module for heating the ablation consumables in the ablation module;

[0007] Among them, the refrigeration module includes: a cold working medium container, a tank body and a heat transfer pipe; the cold working medium container is arranged in the tank body, the heat transfer pipe is arranged between the tank body and the cold working medium container, and is arranged in close contact with the tank body, one end of the heat transfer pipe is connected to the bottom of the cold working medium container, and the other end is connected to the top of the cold working medium container, and the heat transfer pipe is used to heat and vaporize the liquid cold working medium flowing out from the bottom of the cold working medium container and transmit it to the top of the cold working medium container.

[0008] Based on the above scheme, it can be seen that the advantages of the utility model are as follows: heat exchange between liquid nitrogen and air is achieved through the heat transfer tube, thereby generating nitrogen gas for providing pressure for liquid nitrogen transportation, reducing the setting of electrical structures for heating or pressurizing, reducing equipment costs, and reducing the use of electrical components, thereby improving equipment stability and reducing the possibility of failures.

[0009] In a feasible solution, the heat transfer pipe is arranged along the circumference of the tank body and is surrounded multiple times to increase the contact area of ​​heat exchange and improve the heat exchange efficiency.

[0010] In a feasible solution, the heat transfer tube is a copper tube, and a vacuum chamber is formed between the cold medium container and the tank body, which can also achieve a heat preservation effect.

[0011] In a feasible solution, the freezing module further includes: a first solenoid valve, a first three-way valve, a cooling branch, a liquid nitrogen storage device and a safety valve;

[0012] The first solenoid valve is arranged on the heat transfer tube and is used to control the connection and disconnection between the cold medium container and the tank body;

[0013] The safety valve is arranged on the cold medium container.

[0014] In a feasible solution, the reheating module includes: a hot working medium container, a heating branch, a control valve, a temperature regulator, and a temperature monitor;

[0015] The thermal medium container is connected and communicated with the ablation module through the heating branch, the control valve is arranged on the heating branch, and the control valve is used to control the on and off of the heating branch;

[0016] The temperature regulator is arranged on the heating branch and communicated with the heating branch;

[0017] The temperature monitor is arranged on the heating branch and is located between the temperature regulator and the ablation module.

[0018] In a feasible solution, the hot working medium of the rewarming module is anhydrous ethanol; the rewarming module also includes a heater, and the heater is used to heat and vaporize the hot working medium in the hot working medium container.

[0019] In one feasible solution, the cryoablation system further includes: a recovery module;

[0020] The recovery module comprises: a heat exchanger, a recovery tank, a recovery pipeline and a first exhaust valve;

[0021] One end of the recovery pipeline is connected to the ablation module, and the other end is connected to the heat exchanger and the recovery tank in sequence;

[0022] The first exhaust valve is arranged on the recovery tank. Through the recovery module, consumables are saved, and energy saving is further achieved.

[0023] In a feasible solution, the hot working medium of the rewarming module is anhydrous ethanol; the recovery module further comprises: a recovery branch and a delivery pump;

[0024] The recovery tank is connected and communicated with the hot working medium container through a recovery branch;

[0025] The delivery pump is arranged on the recovery branch, and is used to deliver the hot working medium in the recovery tank to the hot working medium container. Through the recovery branch, the consumption of anhydrous ethanol is saved, and energy saving is further achieved.

[0026] In a feasible solution, the hot working medium of the rewarming module is anhydrous ethanol; the recovery module further comprises: a pressure regulating pipeline and a pressure regulating valve; the rewarming module is connected to the hot working medium container through the pressure regulating pipeline; the pressure regulating valve is arranged on the pressure regulating pipeline. After overpressure, the anhydrous ethanol can flow back to the hot working medium container through the exhaust pipe, which increases safety and achieves energy saving.

[0027] In a feasible solution, the cryoablation system further includes: a vacuum module;

[0028] The vacuum module comprises: a vacuum pump and a vacuum pipeline, one end of the vacuum pipeline is connected to the vacuum pump, and the other end of the vacuum pipeline is connected to the ablation module. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0030] Figure 1 This is a schematic diagram of the cryoablation system in the first embodiment of the present utility model;

[0031] Figure 2 Schematic diagram of the cryoablation system in the second embodiment of the present invention.

[0032] 1. Gas working fluid; 2. Hot working fluid container; 3. Pressure reducing valve; 4. Temperature regulator; 5. Heat transfer tube; 6. Cold working fluid container; 7. Tank body; 8. Muffler; 9. Safety valve; 10. Cold working fluid; 11. Liquid nitrogen storage device; 12. Recovery tank; 13. Heat exchanger; 14. Ablation consumables; 15. First quick interface; 16. Second quick interface; 17. Vacuum pump; 18. Vacuum hose; 19. Delivery pump; 20. Heater; 21. Hot working fluid tank body; 22. Hot working fluid storage device;

[0033] P1, first pressure sensor; P2, second pressure sensor; P3, third pressure sensor; P4, fourth pressure sensor; T1, first temperature monitor; T2, second temperature sensor; Z1, vacuum sensor; L1, liquid level gauge;

[0034] G1, heating branch; G2, cooling branch; G3, delivery pipeline; G4, consumables internal circuit; 5, recovery pipeline; G6, vacuum pipeline; G8, pressure regulating pipeline; G9, recovery branch

[0035] F1, control valve; F2, second three-way valve; F3, second solenoid valve; F4, first solenoid valve; F5, first exhaust valve; F6, second exhaust valve; F7, first three-way valve; F8, pressure regulating valve; F9, third three-way valve; D1, first check valve; D2, second check valve; D3, third check valve. DETAILED DESCRIPTION

[0036] In order to make the purpose, technical solution and advantages of the embodiment of the utility model clearer, the technical solution in the embodiment of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiment of the utility model. Obviously, the described embodiment is a part of the embodiment of the utility model, not all of the embodiments. Based on the embodiment of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0037] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0038] In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection, or a communication connection; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0039] The following specific embodiments are used to describe the technical solution of the utility model in detail. The following specific embodiments can be combined with each other, and the same or similar concepts or processes may not be described in detail in some embodiments.

[0040] Embodiment 1

[0041] like Figure 1 and Figure 2 As shown, the cryoablation system of this embodiment includes: a freezing module, a rewarming module and an ablation module. The freezing module and the rewarming module are respectively connected and communicated with the ablation module. The freezing module transports cold fluid to the ablation module for cooling the ablation consumables in the ablation module, and the rewarming module transports hot fluid to the ablation module for heating the ablation consumables in the ablation module.

[0042] The ablation module can use the "cold and hot knife" in the prior art, so this application does not explain the ablation consumables in detail. The ablation consumables (cold and hot knife) in the prior art have a cavity, which is provided with an inlet and an outlet. When the fluid enters the cavity from the inlet, the ablation consumable uses the different fluid components to achieve the effect of heating and cooling, thereby realizing local ablation surgery.

[0043] In this embodiment, the ablation module includes an ablation consumable 14, a second three-way valve F2, a delivery pipeline G3 and a first quick interface 15; a consumable circuit G4 is provided inside the ablation consumable 14, and the consumable circuit G4 includes: an inlet pipe, a return pipe, and a vacuum pipe; the inlet pipe, the return pipe, and the vacuum pipe are sequentially arranged from the inside to the outside; one end of the inlet pipe is connected to the first quick interface 15, and the other end is connected to the inlet of the ablation consumable, the outlet of the ablation consumable is connected to the return pipe, and the vacuum pipe is connected to the vacuum equipment. The delivery pipeline G3 includes a vacuum hose 18, and the delivery pipeline G3 is connected to the first interface of the second three-way valve F2 through one end of the vacuum hose 18, and the other end of the vacuum hose 18 is connected to the first quick interface.

[0044] The freezing module includes: a cold medium container 6, a tank body 7 and a heat transfer tube 5; the cold medium container 6 is arranged in the tank body 7, the heat transfer tube 5 is arranged between the tank body 7 and the cold medium container 6, and is arranged in close contact with the tank body 7, one end of the heat transfer tube 5 is connected to the bottom of the cold medium container 6, and the other end is connected to the top of the cold medium container 6, and the heat transfer tube 5 is used to heat and vaporize the liquid cold medium (liquid nitrogen) flowing out of the bottom of the cold medium container 6 and transfer it to the top of the cold medium container 6. Optionally, as Figure 1 As shown, the heat transfer pipe 5 is arranged around the circumference of the tank body and is surrounded multiple times.

[0045] Optional, such as Figure 1As shown, the freezing module also includes a first solenoid valve F4, a safety valve 9 and a second exhaust valve F6, and the second solenoid valve F4 is arranged on the pressurizing pipeline connecting the heat transfer tube 5 and the cold working medium container 6. After the liquid nitrogen is heat exchanged, it is gasified into nitrogen. The first solenoid valve F4 controls the nitrogen after the heat exchange through the heat transfer tube 5 to pressurize the cold working medium container 6. When the first solenoid valve F4 is closed, the pressure in the heat transfer tube 5 increases to reduce the liquid nitrogen level until the liquid nitrogen completely exits the heat exchange section in the heat transfer tube 5. At this time, the heat transfer tube 5 reaches the maximum pressure (the maximum pressure value is related to the amount of liquid nitrogen in the cold working medium container 6); when the first solenoid valve F4 is opened, the heat transfer tube 5 is connected with the cold working medium container 6, providing pressure to transport the liquid nitrogen to the ablation consumable 14 through the cold supply branch G2, and at this time, the liquid nitrogen also enters the air heat exchange section in the heat transfer tube 5, continuously generating nitrogen, and continuously providing sufficient pressure to transport the liquid nitrogen when the liquid nitrogen level continues to drop. The second exhaust valve F6 and the first solenoid valve F4 cooperate to control the pressure in the cold medium container 6 to be constant within the expected range through timely pressure increase and pressure relief. The safety valve 9 is set to automatically exhaust when the pressure in the cold medium container 6 exceeds the threshold, eliminating the safety hazard when the pressure is too high.

[0046] Optionally, the safety valve 9 is provided with a muffler 8 .

[0047] Optionally, the second exhaust valve F6 is provided with a muffler 8 .

[0048] Optionally, the cooling branch G2 is provided with a first three-way valve F7, and the first three-way valve F7 is used to connect to the liquid nitrogen storage device 11.

[0049] Optionally, the freezing module includes a second solenoid valve F3, which is arranged between the cold working medium container 6 and the first three-way valve F7 and is used to control the output of the cold working medium.

[0050] It is not difficult to conclude from the above scheme that heat exchange between liquid nitrogen and air is achieved through the heat transfer tube, thereby generating nitrogen gas for providing pressure for liquid nitrogen transportation, reducing the setting of electrical structures for heating or pressurizing, and reducing equipment costs. At the same time, reducing the use of electrical components also improves the stability of the equipment, reduces the possibility of failure, and effectively improves the safety performance of the ablation system.

[0051] Optionally, the heat transfer tube 5 is a copper tube, and a vacuum cavity is formed between the cold working medium container 6 and the tank body 7. The cold working medium container 6 is located in the tank body 7, and a vacuum cavity is formed between the two. The copper tube 5 is located in the hollow interlayer, and one end of the copper tube 5 is connected to the bottom of the cold working medium container 6, and this end is arranged on the inner wall of the tank body 7 in a close and surrounding manner, and the other end is provided with a first solenoid valve F4 and leads to the top of the cold working medium container 6; one end of the cold supply branch G2 is arranged in the cold working medium container, and the other end is connected to the interface of the second three-way valve F2.

[0052] like Figure 1 and Figure 2 As shown, the rewarming module includes: a thermal medium container 2, a control valve F1 and a heating branch G1, a temperature regulator 4, and a first temperature monitor T1; the thermal medium container 2 is connected and communicated with the ablation module through the heating branch G1, and the control valve F1 is arranged on the heating branch G1 to control the on-off of the heating branch G1. The temperature regulator 4 is arranged on the heating branch G1 and communicated with the heating branch G1; the first temperature monitor T1 is arranged on the heating branch G1 and is located between the temperature regulator 4 and the ablation module, and is used to monitor the temperature of the thermal medium output by the heating branch G1.

[0053] Optionally, the heat medium used in the rewarming module is anhydrous ethanol or nitrogen, and other heat mediums may also be used. Figure 1 As shown, high-pressure nitrogen is used for rewarming, thereby solving the problem of environmental safety affected by the rewarming working fluid. At the same time, compared with the method of heating and gasifying liquid nitrogen to form nitrogen for rewarming, high-pressure nitrogen simplifies the equipment structure and improves the equipment stability.

[0054] Optional, such as Figure 1 As shown, the rewarming module further includes: a first pressure sensor P1 for detecting the pressure of the hot working medium container, and / or a second pressure sensor P2 for detecting the pressure of the gas heated by the temperature regulator 4.

[0055] Optional, such as Figure 1 As shown, the rewarming module further includes a pressure reducing valve 3, which is disposed between the first pressure sensor P1 and the temperature regulator 4. The high-pressure gas in the thermal medium container 2 is reduced in pressure through the pressure reducing valve 3 to reach a preset working pressure.

[0056] Optionally, the cryoablation system further includes a recovery module; the recovery module includes: a heat exchanger 13, a recovery tank 12 and a recovery pipeline G5; one end of the recovery pipeline G5 is connected to the reflux pipe, and the other end is sequentially connected to the heat exchanger 13 and the recovery tank 12. Optionally, the recovery tank 12 is provided with a fourth pressure sensor P4.

[0057] Optionally, the recovery tank 12 is provided with a first exhaust valve F5 , and the first exhaust valve F5 is provided with a muffler 8 .

[0058] More specifically, combined Figure 1 As shown, the liquid nitrogen input into the ablation consumable 14 during the freezing process and the nitrogen input into the ablation consumable 14 during the rewarming process pass through the recovery pipeline G5 with the third one-way valve D3, and after the liquid nitrogen is vaporized by the heat exchanger 13, it enters the recovery tank 12. The recovery tank 12 can temporarily store the unvaporized liquid nitrogen. The recovery tank 12 has no heat preservation function, and the liquid nitrogen is vaporized in the recovery tank 12. After the nitrogen passes through the recovery tank 12, it is directly discharged from the equipment through the first exhaust valve F5 and the muffler 8.

[0059] For the freezing module, the liquid nitrogen working medium 10 is used to complete the cooling of cryoablation and pre-cooling of the pipeline, and the liquid nitrogen working medium 10 is stored in the cold working medium container 6. The cold working medium container 6 is provided with a liquid level gauge L1 and a third pressure sensor P3. The liquid level gauge L1 is used to monitor the liquid level in the cold working medium container; the third pressure sensor P3 is used to monitor the pressure inside the cold working medium container.

[0060] Optionally, the cryoablation system also includes a vacuum module; the vacuum module includes: a vacuum pump 17 and a vacuum pipeline G6; one end of the vacuum pipeline G6 is connected to the vacuum pump 17, and the other end is connected to the vacuum tube in the ablation consumable 14 through the second quick interface 16.

[0061] Optionally, the vacuum module further includes a vacuum sensor Z1 , which is disposed on the vacuum pipeline G6 and is used to detect the vacuum degree in the pipeline between the ablation consumable 14 and the vacuum pump 16 .

[0062] In order to better explain the structural relationship of the system, the following embodiment introduces the working mode of the system, and its operation can be divided into five stages: power-on self-test; pre-cooling; freezing; pre-heating; re-warming:

[0063] Before starting the machine, the ablation consumable 14 is connected to the first quick interface 15, the second quick interface 16, and the recovery pipeline G5 respectively; and a good contact test is performed;

[0064] POST:

[0065] Step 1: Check the pressure P1 in the hot working medium container 2 to see if it meets the total gas volume required for the operation, and convert the gas volume using the pressure;

[0066] Step 2: Check the amount of liquid nitrogen L1 in the cold medium container 6 to see if the liquid level meets the liquid nitrogen requirement for the operation;

[0067] If it meets the requirements, continue; if it does not meet the requirements, replace the hot working medium container 2 or inject liquid nitrogen (the first three-way valve F7 is replaced to open the connection of the liquid nitrogen container 11 outside the equipment, and the liquid nitrogen container 11 outside the equipment injects liquid nitrogen into the cold working medium container 6);

[0068] Step 3: Detect the pressure P3 in the cold medium container 6, and release the pressure if it exceeds the upper pressure limit;

[0069] Step 4: Turn on the vacuum pump 17, and stop working when the vacuum degree monitored by the vacuum sensor Z1 reaches below 2 Pa;

[0070] The pressure range of the hot working medium container 2 is 3-15 MPa; 5 MPa is the lowest set pressure, which cannot meet the gas volume of one surgical cycle;

[0071] Liquid nitrogen volume description: 0-10% cannot meet the liquid nitrogen volume for one surgical cycle;

[0072] Liquid nitrogen tank pressure description: 0.3-0.4MPa is the cryosurgery pressure, 0.5-0.6Mpa is the pre-cooling pressure, and 0.8 is the safety valve pressure to protect the tank.

[0073] Precooling:

[0074] 1) Detect the pressure of the third pressure sensor P3. If it meets the requirements, no adjustment is required. If it does not meet the requirements, the first solenoid valve F4 and the second exhaust valve F6 are used to perform PID control to adjust the liquid nitrogen pressure. Generally, it is less than the specified maximum pressure value:

[0075] The heat transfer tube 5 is connected to the bottom of the cold medium container 6 and is wound on the inner wall of the tank body 7. The tank body 7 is in contact with the atmosphere. The liquid nitrogen in the heat transfer tube 5 can exchange heat with the atmosphere. After the heat exchange, the liquid nitrogen is gasified and stored in the heat transfer tube 5. At this time, the first solenoid valve F4 is opened to fill the nitrogen in the heat transfer tube 5 into the upper nitrogen in the cold medium container 6, thereby increasing the pressure.

[0076] The above can be used to adjust the liquid nitrogen pressure by PID control through the first solenoid valve F4 and the second exhaust valve F6;

[0077] 2) After the pre-cooling pressure reaches 0.5-0.6 MPa (this pressure is higher than the freezing pressure, which speeds up the pre-cooling speed), the second solenoid valve F3 is opened, the first three-way valve F7 is in the state of leading to the delivery pipe, the second three-way valve F2 is in the state of the cooling branch G2 and the delivery pipe G3, and the liquid nitrogen begins to pass through the ablation consumable 14 in a nitrogen state to exchange heat at the top of the ablation consumable. After a period of time, the liquid nitrogen reaches the front end of the ablation consumable 14, and the pre-cooling ends when the second temperature sensor T2 reaches -185°C;

[0078] 3) After the pre-cooling medium passes through the ablation consumables 14, the liquid nitrogen and nitrogen gas enter the heat exchanger 13 through the recovery pipeline G5, exchange heat with the air, become gas close to room temperature, enter the recovery tank 12, and then pass through the safety valve F5 and the corresponding muffler 8 to be discharged to the atmosphere;

[0079] freezing:

[0080] It is basically the same as the pre-cooling process, except that the pressure is adjusted to 0.3-0.4Mpa, and the freezing starts after the temperature at point 14 of the consumable reaches -185°C. The freezing process ends after the expected freezing amount / time is completed.

[0081] Preheat:

[0082] The pressure reducing valve 3 is in the pressure regulating state all the time, that is, there is gas before the solenoid valve F1. After the freezing starts, when Y minutes are left before the end, the heating mode of the temperature regulator 4 is turned on;

[0083] After the freezing is finished, close the second solenoid valve F3, and adjust the second three-way valve F2 to the passage mode of the heating branch G1 and the delivery pipeline G3;

[0084] The control valve F1 is opened, and the temperature of the ablation consumable 14 is measured to reach the required 80° C., and the preheating is ended;

[0085] The gas passing through the ablation consumables 14 enters the recovery pipeline G5, and then passes through the heat exchanger 13 to achieve heat exchange with the air. The hot air is cooled and discharged into the recovery tank 12, and then discharged through the first exhaust valve F5 and discharged into the atmosphere;

[0086] Rewarming:

[0087] Similar to the preheating state, rewarming is completed after the expected heat energy is delivered.

[0088] Embodiment 2

[0089] Figure 2 Schematic diagram of the cryoablation system in the second embodiment of the present invention. The second embodiment is an alternative to the first embodiment, and the difference is that the thermal working fluid of the rewarming module in the second embodiment is anhydrous ethanol.

[0090] like Figure 2 As shown, the thermal medium is anhydrous ethanol, and the rewarming module further includes a heater 25, which is disposed in the thermal medium container 2 and at least partially immersed in the anhydrous ethanol for heating and vaporizing the anhydrous ethanol.

[0091] Optionally, the recovery module also includes: a recovery branch G9 and a delivery pump 19, the recovery tank 12 is connected and communicated with the hot working fluid container 2 through the recovery branch G9; the delivery pump 19 is arranged on the recovery branch G9, and is used to transport the hot working fluid in the recovery tank 12 to the hot working fluid container 2, thereby realizing the recovery and utilization cycle of the hot working fluid.

[0092] Optional, such as Figure 2 As shown, the recovery module further includes a third three-way valve F9, which is connected and communicated with the recovery branch G9, the hot working medium storage 22 and the hot working medium container 2 respectively.

[0093] Optionally, the recovery module further includes: a pressure regulating pipeline G8 and a pressure regulating valve F8; the rewarming module is connected to the hot working medium container 2 through the pressure regulating pipeline G8; the pressure regulating valve F8 is arranged on the pressure regulating pipeline G8. The hot working medium (anhydrous ethanol) can be returned to the hot working medium container 2 after overpressure, which increases safety and achieves energy saving.

[0094] Please continue reading Figure 2A first one-way valve D1 is provided on the recovery pipeline G5. After passing through the first one-way valve D1, the gaseous ethanol is cooled by the heat exchanger 13 and then liquefied, and then flows back to the recovery tank 12. A second one-way valve D2 is provided on the pressure regulating pipeline G8. After passing through the second one-way valve, the gaseous ethanol is cooled by the heat exchanger 13 and then liquefied, and then flows back to the recovery tank 12.

[0095] Optionally, the rewarming module further includes a hot medium tank 21, and the hot medium container 2 is disposed in the hot medium tank 21 to keep the hot medium container 2 warm. In one embodiment, the hot medium tank 21 is a stainless steel tank.

[0096] Based on the above embodiments, the present application can achieve the following effects:

[0097] 1) Using nitrogen or anhydrous ethanol to rewarm can allow the front end of the ablation consumable 14 to reach 80° C. in a very short time, and can maintain a stable temperature without causing large temperature fluctuations until the rewarming stage is completed.

[0098] 2) Use nitrogen or anhydrous ethanol to reheat evenly, and use a resistance wire heating method. This method can keep the entire ablation consumable 14 blade at the same temperature, greatly increase the heating area, and at the same time will not cause tissue adhesion and carbonization caused by local overtemperature caused by resistance wire.

[0099] 3) Compared with heating with resistance wire, the rewarming efficiency of nitrogen or anhydrous ethanol is greatly improved. The contact surface between the entire ablation consumable 14 blade and the tissue can provide stable heat. When the shape of the ablation consumable 14 blade remains unchanged, the effective area of ​​the rewarmed tissue can be increased.

[0100] In the present invention, unless otherwise clearly specified and limited, a first feature being “on” or “under” a second feature may mean that the first feature and the second feature are in direct contact, or the first feature and the second feature are in indirect contact via an intermediate medium.

[0101] Moreover, the first feature being “above”, “above”, and “above” the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being “below”, “below”, and “below” the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0102] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example" or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0103] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, ordinary technicians in the field should understand that they can still modify the technical solutions recorded in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the utility model.

Claims

1. A cryoablation system, characterized in that: include: Cryomodule, rewarming module and ablation module; The freezing module and the rewarming module are respectively connected and communicated with the ablation module, the freezing module delivers cold working fluid to the ablation module for cooling the ablation consumables in the ablation module, and the rewarming module delivers hot working fluid to the ablation module for heating the ablation consumables in the ablation module; Among them, the refrigeration module includes: a cold working medium container, a tank body and a heat transfer pipe; the cold working medium container is arranged in the tank body, the heat transfer pipe is arranged between the tank body and the cold working medium container, and is arranged in close contact with the tank body, one end of the heat transfer pipe is connected to the bottom of the cold working medium container, and the other end is connected to the top of the cold working medium container, and the heat transfer pipe is used to heat and vaporize the liquid cold working medium flowing out from the bottom of the cold working medium container and transmit it to the top of the cold working medium container.

2. The cryoablation system according to claim 1, characterized in that: The heat transfer pipe is arranged along the circumference of the tank body and is surrounded by multiple circles.

3. The cryoablation system according to claim 1, characterized in that: The heat transfer tube is a copper tube, and a vacuum chamber is formed between the cold medium container and the tank body.

4. The cryoablation system according to claim 1, characterized in that: The refrigeration module further includes: a first solenoid valve, a first three-way valve, a cold supply branch, a cold medium storage device and a safety valve; The cooling branches are respectively connected and communicated with the cold medium container and the ablation module; The first solenoid valve is arranged on the heat transfer tube and is used to control the connection and disconnection between the cold medium container and the tank body; The first three-way valve is arranged on the cooling branch, and the cooling medium storage device is connected and communicated with the first three-way valve; The safety valve is arranged on the cold medium container.

5. The cryoablation system according to any one of claims 1 to 4, characterized in that: The reheating module includes: a hot working medium container, a heating branch, a control valve, a temperature regulator, and a temperature monitor; The thermal medium container is connected and communicated with the ablation module through the heating branch, the control valve is arranged on the heating branch, and the control valve is used to control the on and off of the heating branch; The temperature regulator is arranged on the heating branch and communicated with the heating branch; The temperature monitor is arranged on the heating branch and is located between the temperature regulator and the ablation module.

6. The cryoablation system according to claim 5, characterized in that: The thermal medium of the rewarming module is anhydrous ethanol; the rewarming module also includes a heater, which is used to heat and vaporize the thermal medium in the thermal medium container.

7. The cryoablation system according to claim 5, characterized in that: Also includes: Recycling module; The recovery module comprises: a heat exchanger, a recovery tank, a recovery pipeline and a first exhaust valve; One end of the recovery pipeline is connected to the ablation module, and the other end is connected to the heat exchanger and the recovery tank in sequence; The first exhaust valve is arranged on the recovery tank.

8. The cryoablation system according to claim 7, characterized in that: The thermal medium of the rewarming module is anhydrous ethanol; the recovery module also includes: a recovery branch and a delivery pump; The recovery tank is connected and communicated with the hot working medium container through a recovery branch; The delivery pump is arranged on the recovery branch, and is used for delivering the hot working medium in the recovery tank to the hot working medium container.

9. The cryoablation system according to claim 7, characterized in that: The hot working medium of the re-temperature module is anhydrous ethanol; the recovery module also includes: a pressure regulating pipeline and a pressure regulating valve; The re-temperature module is connected to the hot working medium container through the pressure regulating pipeline; The pressure regulating valve is arranged on the pressure regulating pipeline.

10. The cryoablation system according to claim 1, characterized in that: Also includes: Vacuum module; The vacuum module comprises: a vacuum pump and a vacuum pipeline, one end of the vacuum pipeline is connected to the vacuum pump, and the other end of the vacuum pipeline is connected to the ablation module.

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