Rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride

Abstract

The utility model relates to a rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride, and aims to solve the technical problems that in the rotary evaporation preparation process of L-phenylalanine methyl ester hydrochloride at present, an operator needs to continuously add liquid into a water bath kettle, and stability and safety are poor after a collecting bottle and a second bottle opening connector are installed. A water bath kettle is installed on one side of the surface of the base, a carrier plate is installed on one side of the water bath kettle, a liquid level adjusting pipe is fixedly connected to the top end of the carrier plate, a liquid conveying tank is connected to one end of the liquid level adjusting pipe in a sealed mode, and a liquid guide pipe is connected to the other end of the liquid level adjusting pipe in a sealed mode. According to the L-phenylalanine methyl ester hydrochloride rotary evaporation device, a proper amount of liquid is automatically added into the water bath kettle of the rotary evaporation device, the situation that an operator continuously adds the liquid into the water bath kettle in the rotary evaporation preparation process of L-phenylalanine methyl ester hydrochloride is avoided, and the convenience of the rotary evaporation device in the use process is improved.

Description

Technical Field

[0001] The utility model relates to the field of rotary evaporation devices, in particular to a rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride. Background Art

[0002] The rotary evaporator is an evaporation instrument widely used in laboratories. It is suitable for reflux operation, rapid evaporation of large amounts of solvents, concentration of trace components, and reaction processes that require stirring. The rotary evaporator system can be sealed and decompressed to 400-600 mmHg; the solvent in the distillation flask is heated with a heating bath, and the heating temperature can be close to the boiling point of the solvent; it can also rotate at a speed of 50-160 rpm to form a thin film of the solvent and increase the evaporation area.

[0003] In the process of realizing the utility model, the inventor found that at least the following problems in the prior art have not been solved: during use, the traditional rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride cannot automatically add an appropriate amount of liquid to the water bath of the rotary evaporation device, and the operator needs to continuously add liquid to the water bath during the rotary evaporation preparation of L-phenylalanine methyl ester hydrochloride, which reduces the convenience of the rotary evaporation device during use, and the collection bottle and the second bottle mouth joint are both installed by clamping, and the collection bottle and the second bottle mouth joint are relatively poor in stability and safety after installation. For this reason, it is necessary to design a new technical solution to solve it. Utility Model Content

[0004] The utility model aims to overcome the shortcomings of the prior art, meet practical needs, and provide a rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride, so as to solve the technical problems that in the current rotary evaporation preparation process of L-phenylalanine methyl ester hydrochloride, operators need to continuously add liquid to the water bath and the stability and safety of the collecting bottle and the second bottle mouth joint after installation are relatively poor.

[0005] In order to achieve the purpose of the utility model, the technical scheme adopted by the utility model is as follows: a rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride is designed, comprising a base, a water bath is installed on one side of the base surface, a carrier plate is installed on one side of the water bath, a liquid level regulating tube is fixedly connected to the top of the carrier plate, one end of the liquid level regulating tube is sealed and connected to an infusion tank, the other end of the liquid level regulating tube is sealed and connected to a liquid guide tube, a sealing plate is slidably connected to the inner wall of the liquid level regulating tube, a plurality of liquid flow holes are provided at the edge of the sealing plate, a float is connected to the bottom of the sealing plate through a push rod, a liquid outlet is provided at the bottom of the infusion tank, a groove is provided on the other side of the base surface, a bidirectional threaded screw is rotatably connected inside the groove, one end of the bidirectional threaded screw is fixedly connected to a turntable, both sides of the bidirectional threaded screw are connected to sleeve columns through moving blocks, the sleeve columns are connected to extension columns through springs, and the other end of the extension column is fixedly connected to a collecting bottle clamp.

[0006] Preferably, a mounting arm is fixedly connected to the edge of one end of the base, a mounting bracket is fixedly connected to one side of the mounting arm, a driving mechanism is rotatably connected inside the mounting bracket, one end of the driving mechanism is connected to a charging bottle via a first bottle mouth joint, a condenser is installed at the other end of the driving mechanism, and the bottom of the condenser is sealed and connected to a second bottle mouth joint.

[0007] Preferably, one end of the push rod is fixedly connected to the middle of the bottom of the sealing plate, the other end of the push rod passes through the interior of the liquid guide tube and is fixedly connected to one end of the float, and the bottom end of the liquid guide tube is flush with the upper edge of the water bath.

[0008] Preferably, the plurality of liquid flow holes are located at the periphery of the liquid conduit, and the liquid outlet is located at the inner periphery of the liquid flow holes.

[0009] Preferably, the moving block is connected to both sides of the bidirectional threaded screw via threads, one end of the sleeve is fixedly connected to one end of the moving block and is slidably connected to the upper surface of the base.

[0010] Preferably, the spring is movably connected to the inner wall of the sleeve column, one end of the extension column is slidably connected to the inner wall of the sleeve column, and the other end of the extension column is fixedly connected to the bottom of the collecting bottle clamp, and the center point of the two collecting bottle clamps corresponds to the position of the second bottle mouth joint.

[0011] Compared with the prior art, the beneficial effects of the present invention are:

[0012] The utility model combines a liquid level regulating tube, an infusion tank, a liquid guiding tube, a sealing plate, a liquid flow hole, a push rod, a floating ball and a liquid outlet. When the charging bottle is subjected to rotary evaporation in the water bath, the liquid in the water bath will be consumed. When the water level in the water bath drops, the floating ball will drop along with the water level. At this time, the floating ball will drive the sealing plate to move downward in the liquid level regulating tube through the push rod, so that the sealing plate is separated from the position of the liquid outlet. At this time, the liquid stored in the infusion tank will flow into the interior of the liquid level regulating tube from the liquid outlet, and then the liquid will be transported to the interior of the liquid guiding tube through the liquid flow hole, and then flow into the water bath. When the water level in the water bath rises, the floating ball will drive the sealing plate to move upward through the push rod, so that the sealing plate can seal the liquid outlet, so that an appropriate amount of liquid can be automatically added to the water bath of the rotary evaporation device, thereby avoiding the operator from constantly adding liquid to the water bath during the rotary evaporation preparation process of L-phenylalanine methyl ester hydrochloride, and improving the convenience of the rotary evaporation device during use.

[0013] When the water level in the water bath is lower than the height of the liquid level regulating tube, the float will drive the sealing plate to move directly to the bottom of the liquid level regulating tube through the push rod. At this time, the liquid flow hole on the sealing plate will be against the connection between the liquid level regulating tube and the liquid guide tube, so as to seal the liquid level regulating tube, so as to avoid the liquid in the infusion tank from flowing out when the filling bottle has not yet been rotary evaporated, and reduce the number of times the liquid is added to the infusion tank.

[0014] When the collecting bottle is connected with the second bottle mouth joint of the condenser, the operator first adjusts the distance between the two collecting bottle clamps according to the size of the collecting bottle, and then turns the knob so that the knob drives the two moving blocks to move relative to or toward each other inside the groove through the bidirectional threaded screw, so that the moving blocks drive the collecting bottle clamps to move relative to or toward each other through the sleeve column and the extension column. After the distance between the collecting bottle clamps is adjusted, stop turning the knob, place the collecting bottle on the collecting bottle clamp, and then slowly release the collecting bottle clamp. At this time, the spring will generate elastic force on the extension column, so that the extension column slides inside the sleeve column, and the collecting bottle clamp drives the collecting bottle to move upward, so that the bottle mouth of the collecting bottle is connected to the second bottle mouth joint. Compared with the traditional collecting bottle and the second bottle mouth joint, the installation is more stable and safe, and the phenomenon of the collecting bottle falling off the second bottle mouth joint and causing damage to it is avoided. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the structure of the utility model;

[0016] Figure 2 This is a schematic diagram of the groove structure of the utility model;

[0017] Figure 3 This is a cross-sectional view of the liquid level regulating tube of the utility model;

[0018] Figure 4 It is a cross-sectional view of the sleeve column of the utility model;

[0019] Figure 5 It is a top view of the sealing plate of the utility model;

[0020] In the figure: 1, base; 11, water bath; 12, mounting arm; 13, mounting frame; 14, driving mechanism; 15, first bottle mouth connector; 16, charging bottle; 17, condenser; 18, second bottle mouth connector;

[0021] 2. Carrier plate; 21. Liquid level regulating tube; 22. Infusion tank; 23. Liquid guide tube; 24. Sealing plate; 25. Liquid flow hole; 26. Ejector rod; 27. Float; 28. Liquid outlet;

[0022] 3. Groove; 31. Bidirectional threaded screw; 32. Turntable; 33. Moving block; 34. Sleeve column; 35. Spring; 36. Extension column; 37. Collection bottle clamp. DETAILED DESCRIPTION

[0023] The utility model is further described below in conjunction with the accompanying drawings and embodiments:

[0024] Example 1: Rotary evaporation apparatus for preparing L-phenylalanine methyl ester hydrochloride, see Figures 1 to 5, comprising a base 1, a water bath 11 is installed on one side of the surface of the base 1, a carrier plate 2 is installed on one side of the water bath 11, a liquid level regulating tube 21 is fixedly connected to the top of the carrier plate 2, one end of the liquid level regulating tube 21 is sealed and connected to an infusion tank 22, the other end of the liquid level regulating tube 21 is sealed and connected to a liquid guide tube 23, the inner wall of the liquid level regulating tube 21 is slidably connected to a sealing plate 24, a plurality of liquid flow holes 25 are opened at the edge of the sealing plate 24, and the positions of the plurality of liquid flow holes 25 are located at the liquid guide tube The outer periphery of the sealing plate 23, the bottom of the sealing plate 24 is connected to a floating ball 27 through a push rod 26, one end of the push rod 26 is fixedly connected to the middle of the bottom of the sealing plate 24, the other end of the push rod 26 passes through the interior of the liquid guide tube 23, and is fixedly connected to one end of the floating ball 27, the bottom end of the liquid guide tube 23 is flush with the upper edge of the water bath 11, and a liquid outlet 28 is opened at the bottom of the infusion tank 22, and the liquid outlet 28 is located inside the liquid flow hole 25. When the charging bottle 16 is rotary evaporated in the water bath 11, the liquid outlet 28 is located inside the liquid flow hole 25. When the water level in the water bath 11 drops, the float 27 will drop along with the water level. At this time, the float 27 will drive the sealing plate 24 to move downward in the liquid level regulating tube 21 through the push rod 26, so that the sealing plate 24 is separated from the position of the liquid outlet 28. At this time, the liquid stored in the infusion tank 22 will flow from the liquid outlet 28 into the interior of the liquid level regulating tube 21, and then the liquid will be transported to the interior of the liquid guide tube 23 through the liquid flow hole 25, and then flow into the water bath 11. When the water level in the water bath 11 rises, the float 27 will drive the sealing plate 24 to move upward through the push rod 26, so that the sealing plate 24 can seal the liquid outlet 28, so as to realize the automatic addition of an appropriate amount of liquid into the water bath 11 of the rotary evaporation device, thereby avoiding the operator from constantly adding liquid to the water bath 11 during the rotary evaporation preparation of L-phenylalanine methyl ester hydrochloride, thereby improving the convenience of the rotary evaporation device during use;

[0025] When the water level in the water bath 11 is lower than the height of the liquid level regulating tube 21, the float 27 will drive the sealing plate 24 to move directly to the bottom end of the liquid level regulating tube 21 through the push rod 26. At this time, the liquid flow hole 25 on the sealing plate 24 will be against the connection between the liquid level regulating tube 21 and the liquid guide tube 23, so as to seal the liquid level regulating tube 21, so as to avoid the liquid in the infusion tank 22 from flowing out when the charging bottle 16 has not yet been rotary evaporated, thereby reducing the number of times the liquid is added to the infusion tank 22.

[0026] It is worth mentioning that see Figure 2 and Figure 4The other side of the surface of the base 1 is provided with a groove 3, and a bidirectional threaded screw rod 31 is rotatably connected inside the groove 3, and one end of the bidirectional threaded screw rod 31 is fixedly connected to a turntable 32, and both sides of the bidirectional threaded screw rod 31 are connected to a sleeve column 34 through a moving block 33, and the sleeve column 34 is connected to an extension column 36 through a spring 35, and the other end of the extension column 36 is fixedly connected to a collecting bottle clamping plate 37, and the moving block 33 is connected to both sides of the bidirectional threaded screw rod 31 through a thread, and one end of the sleeve column 34 is fixedly connected to one end of the moving block 33 and is slidably connected to the upper surface of the base 1, and the spring 35 is movably connected to the inner wall of the sleeve column 34, and one end of the extension column 36 is slidably connected to the inner wall of the sleeve column 34, and the other end of the extension column 36 is fixedly connected to the bottom of the collecting bottle clamping plate 37, and the center point of the two collecting bottle clamping plates 37 corresponds to the position of the second bottle mouth joint 18. When the collecting bottle is connected to the second bottle mouth joint 18 of the condenser 17, the operator The operator first adjusts the spacing between the two collecting bottle clamps 37 according to the size of the collecting bottle, and then turns the knob so that the knob drives the two moving blocks 33 to move relative to or toward each other inside the groove 3 through the bidirectional threaded screw 31, so that the moving blocks 33 drive the collecting bottle clamps 37 to move relative to or toward each other through the sleeve column 34 and the extension column 36. After the spacing between the collecting bottle clamps 37 is adjusted, stop turning the knob, place the collecting bottle on the collecting bottle clamps 37, and then slowly release the collecting bottle clamps 37. At this time, the spring 35 will generate elastic force on the extension column 36, so that the extension column 36 slides inside the sleeve column 34, and the collecting bottle clamps 37 drive the collecting bottle to move upward, so that the bottle mouth of the collecting bottle is connected to the second bottle mouth joint 18. Compared with the traditional collecting bottle and the second bottle mouth joint 18, the installation is more stable and safe, and the phenomenon of the collecting bottle falling from the second bottle mouth joint 18 and causing damage to it is avoided.

[0027] For further information, see Figure 1 A mounting arm 12 is fixedly connected to the edge of one end of the base 1, a mounting frame 13 is fixedly connected to one side of the mounting arm 12, a driving mechanism 14 is rotatably connected inside the mounting frame 13, one end of the driving mechanism 14 is connected to a charging bottle 16 via a first bottle mouth joint 15, a condenser 17 is installed at the other end of the driving mechanism 14, and a second bottle mouth joint 18 is sealed at the bottom of the condenser 17. When the charging bottle 16 rotates, the driving mechanism 14 will drive the charging bottle 16 to rotate via the first bottle mouth joint 15, and the steam generated in the charging bottle 16 will enter the condenser 17 for condensation.

[0028] In addition, the components designed in the present invention are all universal standard parts or components known to technical personnel in the field. Their structures and principles can be known to technical personnel through technical manuals or through conventional experimental methods. They can be fully implemented by technical personnel in the field, and there is no need to elaborate. The content protected by the present invention does not involve improvements to internal structures and methods.

[0029] The embodiments of the present invention disclose preferred embodiments, but are not limited thereto. A person skilled in the art can easily understand the spirit of the present invention based on the above embodiments and make different extensions and changes. However, as long as they do not deviate from the spirit of the present invention, they are all within the protection scope of the present invention.

Claims

1. A rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride, comprising a base (1), characterized in that: A water bath (11) is installed on one side of the surface of the base (1), a carrier plate (2) is installed on one side of the water bath (11), a liquid level regulating tube (21) is fixedly connected to the top of the carrier plate (2), one end of the liquid level regulating tube (21) is sealedly connected to an infusion tank (22), the other end of the liquid level regulating tube (21) is sealedly connected to a liquid guide tube (23), the inner wall of the liquid level regulating tube (21) is slidably connected to a sealing plate (24), a plurality of liquid flow holes (25) are provided at the edge of the sealing plate (24), and the bottom of the sealing plate (24) is connected via a push rod (26). A floating ball (27) is connected, a liquid outlet (28) is provided at the bottom of the infusion tank (22), a groove (3) is provided on the other side of the surface of the base (1), a bidirectional threaded screw (31) is rotatably connected inside the groove (3), one end of the bidirectional threaded screw (31) is fixedly connected to a turntable (32), both sides of the bidirectional threaded screw (31) are connected to sleeve columns (34) via moving blocks (33), the sleeve columns (34) are connected to extension columns (36) via springs (35), and the other end of the extension column (36) is fixedly connected to a collecting bottle clamp (37).

2. The rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride according to claim 1, characterized in that: A mounting arm (12) is fixedly connected to the edge of one end of the base (1), a mounting frame (13) is fixedly connected to one side of the mounting arm (12), a driving mechanism (14) is rotatably connected inside the mounting frame (13), one end of the driving mechanism (14) is connected to a charging bottle (16) via a first bottle mouth joint (15), a condenser (17) is installed at the other end of the driving mechanism (14), and the bottom of the condenser (17) is sealed and connected to a second bottle mouth joint (18).

3. The rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride according to claim 1, characterized in that: One end of the push rod (26) is fixedly connected to the middle of the bottom of the sealing plate (24), the other end of the push rod (26) passes through the interior of the liquid guide tube (23) and is fixedly connected to one end of the float (27), and the bottom end of the liquid guide tube (23) is flush with the upper edge of the water bath (11).

4. The rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride according to claim 1, characterized in that: The plurality of liquid flow holes (25) are located at the periphery of the liquid guide tube (23), and the liquid outlet (28) is located at the inner periphery of the liquid flow holes (25).

5. The rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride according to claim 1, characterized in that: The moving block (33) is connected to both sides of the bidirectional threaded screw (31) via threads, and one end of the sleeve column (34) is fixedly connected to one end of the moving block (33) and is slidably connected to the upper surface of the base (1).

6. The rotary evaporation device for preparing L-phenylalanine methyl ester hydrochloride according to claim 2, characterized in that: The spring (35) is movably connected to the inner wall of the sleeve column (34), one end of the extension column (36) is slidably connected to the inner wall of the sleeve column (34), and the other end of the extension column (36) is fixedly connected to the bottom of the collecting bottle clamp (37), and the center point of the two collecting bottle clamps (37) corresponds to the position of the second bottle mouth joint (18).

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