Three-dimensional cell culture support

By designing an adjustable fixed block system, the problem that the existing three-dimensional cell culture scaffold cannot adapt to the Petri dishes of different sizes is solved, and the stable fixation of Petri dishes of different sizes is achieved, which improves the use effect of the culture scaffold.

CN222593881UActive Publication Date: 2025-03-11URUMQI MATERNAL & CHILD HEALTH HOSPITAL
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202420508289.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-15
Publication Date
2025-03-11
Estimated Expiration
2034-03-15

AI Technical Summary

Technical Problem

The existing three-dimensional cell culture scaffolds cannot adapt to different sizes of Petri dishes, resulting in the fixing blocks being unable to abut on the Petri dishes, affecting the fixing effect of the culture scaffolds.

Method used

A three-dimensional cell culture scaffold including a column and mounting assembly is designed to drive the fixing blocks to move on the carrier plate by adjusting the guide rail and adjusting screws to achieve fixation of Petri dishes of different sizes.

Benefits of technology

It effectively improves the fixation effect of the culture scaffold on the Petri dish, and can adapt to different sizes of the Petri dish, thereby improving the use effect of the culture scaffold.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN222593881U_ABST
    Figure CN222593881U_ABST
Patent Text Reader

Abstract

The utility model relates to the technical field of three-dimensional cell culture, in particular to a three-dimensional cell culture support which comprises a stand column and an installation assembly. The mounting assembly comprises a bearing plate, a mounting block, a fixing block, an adjusting guide rail, an adjusting block, a fixing component and an adjusting component, the mounting block is fixedly mounted on one side of the stand column, the bearing plate is slidably connected with the stand column and located on the side, close to the mounting block, of the stand column, the adjusting guide rail is fixedly mounted on the side, away from the mounting block, of the bearing plate, and the adjusting component is arranged on the bearing plate; the adjusting block is connected with the adjusting guide rail and is connected with the adjusting component, the fixing block is fixedly connected with the adjusting block and is in sliding connection with the bearing plate, and the fixing component is connected with the bearing plate and is connected with the stand column, so that the fixing block can fix culture dishes with different sizes on the bearing plate, and the fixing effect of the culture bracket on the culture dishes is improved.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model belongs to the technical field of three-dimensional cell culture, and in particular relates to a three-dimensional cell culture bracket. Background Art

[0002] Three-dimensional cell culture refers to the co-culturing of carriers with different materials having three-dimensional structures with various types of cells in vitro. When culturing three-dimensional cells, the culture dish is placed on a culture support. The usual culture support is fixed, and the spacing between the support plates cannot be adjusted, making it inconvenient for staff to take the culture dish on the support plate, thus affecting the use effect of the culture support.

[0003] The prior art CN218478745U discloses a bracket for fixing a culture dish, comprising a fixing block, a carrying plate, a culture vessel body, a pulling block, a pulling rod, a column, a groove and a collar, wherein the fixing block is fixedly mounted on the carrying plate, and the fixing block on the carrying plate limits the culture vessel body, and the pulling block on the corresponding carrying plate is pulled so that the pulling block pulls the pulling rod along the through hole and the sliding hole, so that the pulling rod is disengaged from a groove on the column, and at this time, the limiting of the collar on the column is cancelled, and the carrying plate is rotated, and the collar is rotated synchronously, so that the carrying plate moves from the original fixed position, and the carrying plate is rotated along the column so that the carrying plate is rotated to pick up the culture vessel body, thereby improving the use effect of the culture bracket.

[0004] In normal use, the fixing block is fixedly mounted on the supporting plate, and the fixing block on the supporting plate limits the culture vessel body. Due to the different sizes of culture vessels, the fixing block on the supporting plate cannot abut against culture vessels of different sizes, so that the fixing block cannot fix culture vessels of different sizes on the supporting plate, thereby affecting the fixing effect of the culture support on the culture vessel. Utility Model Content

[0005] The purpose of the utility model is to solve the problem that culture dishes of different sizes cannot be abutted by the fixing blocks on the carrying plate, so that the fixing blocks cannot fix the culture dishes of different sizes on the carrying plate, thereby affecting the fixing effect of the culture support on the culture dishes.

[0006] In order to achieve the above technical purpose, the technical solution adopted by the utility model is as follows:

[0007] The utility model provides a three-dimensional cell culture support, comprising a column and a mounting assembly; the mounting assembly comprises a bearing plate, a mounting block, a fixed block, an adjustment guide rail, an adjustment block, a fixed component and an adjustment component, the mounting block is fixedly mounted on one side of the column, the bearing plate is slidably connected to the column and is located on a side of the column close to the mounting block, the adjustment guide rail is fixedly mounted on a side of the bearing plate away from the mounting block, the adjustment component is arranged on the bearing plate, the adjustment block is connected to the adjustment guide rail and to the adjustment component, the fixed block is fixedly connected to the adjustment block and is slidably connected to the bearing plate, and the fixed component is connected to the bearing plate and to the column.

[0008] Wherein, the adjusting component includes an adjusting screw and a rotating block, the adjusting screw is rotatably connected to the adjusting guide rail and is threadedly connected to the adjusting block; the rotating block is fixedly connected to the adjusting screw and is located on a side of the adjusting screw away from the column.

[0009] Among them, the fixed component includes a clamping rod, a movable frame and a driving component, the movable frame is fixedly installed on the side of the supporting plate away from the fixed block; the clamping rod is slidably connected to the movable frame and is slidably connected to the column; the driving component is arranged on the movable frame and connected to the clamping rod.

[0010] Wherein, the driving component includes a slider and a driving spring, the slider is fixedly connected to the clamping rod and slidably connected to the movable frame; one end of the driving spring is connected to the slider, and the other end of the driving spring is connected to the slider.

[0011] Wherein, the adjusting component also includes a protective pad and a mounting screw, wherein the mounting screw is threadedly connected to the fixing block and is located on a side of the fixing block away from the column; the protective pad is threadedly connected to the mounting screw and is located on a side of the mounting screw close to the fixing block.

[0012] The utility model provides a three-dimensional cell culture support, wherein a culture dish is placed on the carrier plate, and the rotating block is rotated to drive the adjusting screw to rotate on the adjusting guide rail, and the adjusting screw drives the adjusting block to drive the fixed block to move on the carrier plate, and drives the fixed block to abut against the culture dish, so that the fixed block can fix culture dishes of different sizes on the carrier plate, thereby improving the fixing effect of the culture support on the culture dish. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] The present invention can be further described by the non-limiting embodiments given in the accompanying drawings.

[0014] Figure 1It is a schematic diagram of the overall structure of the three-dimensional cell culture scaffold according to the first embodiment of the utility model.

[0015] Figure 2 It is a structural schematic diagram of the adjusting block and the adjusting screw rod of the utility model.

[0016] Figure 3 It is a schematic diagram of the overall structure of the three-dimensional cell culture scaffold according to the second embodiment of the utility model.

[0017] In the figure: 101-column, 102-bearing plate, 103-mounting block, 104-fixed block, 105-adjusting guide rail, 106-adjusting block, 107-adjusting screw, 108-rotating block, 109-clamping rod, 110-movable frame, 111-slider, 112-driving spring, 201-protective pad, 202-mounting screw. DETAILED DESCRIPTION

[0018] In order to enable those skilled in the art to better understand the present invention, the technical solution of the present invention is further described below in conjunction with the accompanying drawings and embodiments.

[0019] Embodiment 1:

[0020] like Figure 1 and Figure 2 As shown, Figure 1 The overall structure diagram of the three-dimensional cell culture scaffold of the first embodiment of the utility model is as follows Figure 2 10 is a schematic diagram of the structure of the adjusting block and the adjusting screw of the utility model. The utility model provides a three-dimensional cell culture support, including a column 101 and a mounting assembly; the mounting assembly includes a bearing plate 102, a mounting block 103, a fixed block 104, an adjusting guide rail 105, an adjusting block 106, a fixing member and an adjusting member, the adjusting member includes an adjusting screw 107 and a rotating block 108, the fixing member includes a clamping rod 109, a movable frame 110 and a driving component, the driving component includes a slider 111 and a driving spring 112, and the above-mentioned scheme solves the problem that the culture dishes are of different sizes, the fixing block 104 on the bearing plate 102 cannot abut on the culture dishes of different sizes, so that the fixing block 104 cannot fix the culture dishes of different sizes on the bearing plate 102, thereby affecting the fixing effect of the culture support on the culture dishes. It can be understood that the above-mentioned scheme can be used in the case where the fixing block 104 is fixedly installed on the bearing plate 102, and the fixing block 104 on the bearing plate 102 limits the culture vessel body.

[0021] According to this specific embodiment, by placing the culture dish on the supporting plate 102, the adjusting member drives the adjusting block 106 to move on the adjusting guide rail 105, and the adjusting block 106 drives the fixing block 104 to move on the supporting plate 102, driving the fixing block 104 to abut against the culture dish, so that the fixing block 104 can fix culture dishes of different sizes on the supporting plate 102, thereby improving the fixing effect of the culture support on the culture dish.

[0022] The mounting block 103 is fixedly mounted on one side of the column 101, the bearing plate 102 is slidably connected to the column 101 and is located on a side of the column 101 close to the mounting block 103, the adjustment rail 105 is fixedly mounted on a side of the bearing plate 102 away from the mounting block 103, the adjustment member is arranged on the bearing plate 102, the adjustment block 106 is connected to the adjustment rail 105 and to the adjustment member, the fixed block 104 is fixedly connected to the adjustment block 106 and is slidably connected to the bearing plate 102, the fixed member is connected to the bearing plate 102 and is connected to the column 101. The mounting block 103 is connected to the column 101, the mounting block 103 is a cylinder with a through hole on the top, there are multiple mounting blocks 103, and the mounting blocks 103 are fixedly mounted on the outside of the column 101 through the through holes of the mounting blocks 103, and the left top of the supporting plate 102 is designed with a through hole, there are multiple supporting plates 102, and the supporting plates 102 are slidably mounted on the column 101 through the through holes of the supporting plate 102, and the bottom of the through hole of the supporting plate 102 abuts on the mounting block 103, and a mounting groove is provided on the top right side of the supporting plate 102, and the adjusting guide rail 105 is a rectangular parallelepiped with a groove on the top. There are multiple adjustment rails 105, and the adjustment rails 105 are fixedly installed on the grooves of the carrier plate 102. There are multiple adjustment blocks 106, and the adjustment block 106 is a rectangular parallelepiped with a through threaded hole on the left side. There are multiple adjustment components, and the adjustment components are connected to the through threaded holes of two adjustment blocks 106. The adjustment components drive the two adjustment blocks 106 to move on the grooves of the adjustment rails 105. The fixed block 104 is arc-shaped, and there are multiple fixed blocks 104. The bottom of the fixed block 104 is fixedly connected to the adjustment block 106. The side of the column 101 is designed with multiple positioning holes. There are multiple parts, the fixing component is arranged at the bottom of the carrier plate 102 and connected to the positioning hole of the column 101, the fixing component fixes the carrier plate 102 on the column 101, and by placing the culture dish on the carrier plate 102, the adjusting component drives the adjusting block 106 to move on the adjusting guide rail 105, and the adjusting block 106 drives the fixing block 104 to move on the carrier plate 102, driving the fixing block 104 to abut against the culture dish, so that the fixing block 104 can fix the culture dishes of different sizes on the carrier plate 102, thereby improving the fixing effect of the culture support on the culture dish.

[0023] Secondly, the adjusting screw 107 is rotatably connected to the adjusting guide rail 105 and is threadedly connected to the adjusting block 106; the rotating block 108 is fixedly connected to the adjusting screw 107 and is located on a side of the adjusting screw 107 away from the column 101. A through hole is designed on the right side of the adjusting guide rail 105. The adjusting screw 107 is connected to the through threaded holes of the two adjusting blocks 106 through the through hole of the adjusting guide rail 105. The right end of the adjusting screw 107 is fixedly connected to the left side of the rotating block 108. The adjusting screw 107 is driven to rotate on the adjusting guide rail 105 by rotating the rotating block 108. The adjusting screw 107 drives the adjusting block 106 to drive the fixed block 104 to move on the supporting plate 102, thereby driving the fixed block 104 to abut against the culture dish.

[0024] Then, the movable frame 110 is fixedly installed on a side of the supporting plate 102 away from the fixed block 104; the clamping rod 109 is slidably connected to the movable frame 110 and is slidably connected to the column 101; the driving component is arranged on the movable frame 110 and connected to the clamping rod 109. The movable frame 110 is a rectangular parallelepiped with a groove on the top. The top of the movable frame 110 is fixedly connected to the bottom of the supporting plate 102. A through hole is designed on the left side of the movable frame 110. The clamping rod 109 is slidably connected to the positioning hole of the column 101 through the through hole of the movable frame 110. The driving component is arranged inside the movable frame 110. The clamping rod 109 is driven by the driving component to move on the movable frame 110, and the clamping rod 109 is inserted into the column 101, so that the supporting plate 102 is fixed on the column 101.

[0025] Finally, the slider 111 is fixedly connected to the clamping rod 109 and is slidably connected to the movable frame 110; one end of the driving spring 112 is connected to the slider 111, and the other end of the driving spring 112 is connected to the slider 111. The slider 111 is a rectangular parallelepiped with a through hole designed on the left side. The slider 111 is fixedly installed on the clamping rod 109 through the through hole of the slider 111. The driving spring 112 is located inside the movable frame 110 to support the slider 111. The slider 111 is driven by the driving spring 112 to drive the clamping rod 109 to move on the movable frame 110, thereby driving the clamping rod 109 to insert into the column 101.

[0026] When using a three-dimensional cell culture support of the present embodiment, the culture dish is placed on the carrier plate 102, and the rotating block 108 is rotated to drive the adjusting screw 107 to rotate on the adjusting guide rail 105. The adjusting screw 107 drives the adjusting block 106 to drive the fixed block 104 to move on the carrier plate 102, and drives the fixed block 104 to abut against the culture dish, so that the fixed block 104 can fix culture dishes of different sizes on the carrier plate 102, thereby improving the fixing effect of the culture support on the culture dish.

[0027] Embodiment 2:

[0028] like Figure 3 As shown, Figure 3 1 is a schematic diagram of the overall structure of the three-dimensional cell culture support according to the second embodiment of the present invention. Based on the first embodiment, the regulating component of this embodiment further includes a protective pad 201 and a mounting screw 202 .

[0029] According to this specific embodiment, the fixing block 104 drives the pad 201 to move, and drives the pad 201 to abut against the culture dish, thereby improving the fixing effect of the culture dish.

[0030] Among them, the mounting screw 202 is threadedly connected to the fixing block 104 and is located on a side of the fixing block 104 away from the column 101; the protective pad 201 is threadedly connected to the mounting screw 202 and is located on a side of the mounting screw 202 close to the fixing block 104, a plurality of threaded holes are designed on the inner side of the fixing block 104, the protective pad 201 is arc-shaped, the protective pad 201 is made of rubber, and a plurality of mounting holes are designed on the inner side of the protective pad 201, the protective pad 201 has multiple holes, the mounting screw 202 has multiple holes, the mounting screw 202 is connected to the threaded hole of the fixing block 104 through the mounting hole of the protective pad 201, the protective pad 201 is installed on the inner side of the fixing block 104, the protective pad 201 is driven to move by the fixing block 104, and the protective pad 201 is driven to abut against the culture dish, thereby improving the fixing effect of the culture dish.

[0031] When using a three-dimensional cell culture scaffold of this embodiment, the mounting screw 202 mounts the pad 201 on the inner side of the fixing block 104. The fixing block 104 drives the pad 201 to move and drives the pad 201 to abut against the culture dish, thereby improving the fixing effect of the culture dish.

[0032] The above embodiments are merely illustrative of the principles and effects of the present invention, and are not intended to limit the present invention. Anyone familiar with the technology may modify or change the above embodiments without violating the spirit and scope of the present invention. Therefore, all equivalent modifications or changes made by those with ordinary knowledge in the relevant technical field without departing from the spirit and technical ideas disclosed in the present invention shall still be covered by the claims of the present invention.

Claims

1. A three-dimensional cell culture scaffold, comprising a column, characterized in that: Also included are mounting components; The mounting assembly includes a bearing plate, a mounting block, a fixed block, an adjusting rail, an adjusting block, a fixing member and an adjusting member. The mounting block is fixedly mounted on one side of the column. The bearing plate is slidably connected to the column and is located on a side of the column close to the mounting block. The adjusting rail is fixedly mounted on a side of the bearing plate away from the mounting block. The adjusting member is arranged on the bearing plate. The adjusting block is connected to the adjusting rail and to the adjusting member. The fixing block is fixedly connected to the adjusting block and is slidably connected to the bearing plate. The fixing member is connected to the bearing plate and to the column.

2. The three-dimensional cell culture scaffold according to claim 1, characterized in that: The adjusting component comprises an adjusting screw and a rotating block. The adjusting screw is rotatably connected to the adjusting guide rail and is threadedly connected to the adjusting block. The rotating block is fixedly connected to the adjusting screw and is located on a side of the adjusting screw away from the column.

3. The three-dimensional cell culture scaffold according to claim 1, characterized in that: The fixing component includes a clamping rod, a movable frame and a driving component. The movable frame is fixedly installed on a side of the supporting plate away from the fixed block; the clamping rod is slidably connected to the movable frame and is slidably connected to the column; the driving component is arranged on the movable frame and connected to the clamping rod.

4. The three-dimensional cell culture scaffold according to claim 3, characterized in that: The driving component includes a slider and a driving spring. The slider is fixedly connected to the clamping rod and slidably connected to the movable frame. One end of the driving spring is connected to the slider, and the other end of the driving spring is connected to the slider.

5. The three-dimensional cell culture scaffold according to claim 1, characterized in that: The adjusting component also includes a protective pad and a mounting screw, wherein the mounting screw is threadedly connected to the fixing block and is located on a side of the fixing block away from the column; the protective pad is threadedly connected to the mounting screw and is located on a side of the mounting screw close to the fixing block.