Skin simulation body and mold for calibrating percutaneous jaundice detector

Abstract

The utility model provides a skin simulation body and a mold for calibrating a percutaneous jaundice detector. The skin simulation body comprises a first simulation layer and a second simulation layer; a plurality of black substance particles are arranged in the first simulation layer; a blood vessel simulation channel distributed in a branch shape is arranged between the first simulation layer and the second simulation layer, and the blood vessel simulation channel is filled with a bilirubin solution. According to the technical scheme, the first simulation layer is used for simulating an epidermal layer, the second simulation layer containing the blood vessel simulation channel is used for simulating a corium layer and subcutaneous tissue, black substance particles in the first simulation layer can simulate melanin, and a bilirubin solution with nominal concentration is injected into the blood vessel simulation channel to simulate blood. And a plurality of white scattering particles are embedded in the first simulation layer and the second simulation layer. The skin simulation body is used for calibrating a percutaneous jaundice detector, factors such as melanin, blood and skin scattering in skin are comprehensively considered, and the accuracy of calibration and measurement of the jaundice detector is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of jaundice instrument calibration detection, in particular to a skin phantom and a mold for calibrating a transcutaneous jaundice detector. Background Art

[0002] Neonatal jaundice is a very common disease. About 60% of healthy babies will have jaundice symptoms. The main reason is the increased production of bilirubin in newborn blood cells. Due to the developmental restrictions of organs such as the liver and intestines, the ability of newborns to collect and excrete bilirubin is limited, resulting in an increase in the level of free bilirubin in the blood, which diffuses out of the blood system and enters adjacent tissues, forming yellowing of the skin color, mucous membranes, etc. Usually, most jaundice is physiological and will heal itself after a period of time. If bilirubin diffuses to the nervous tissue through the underdeveloped blood-brain barrier, it will cause kernicterus, which may cause hearing loss, cerebral palsy, mental retardation, etc. in the child. Therefore, early and continuous detection of jaundice is very important.

[0003] The transcutaneous jaundice detector (hereinafter referred to as the jaundice meter) is an instrument that can non-invasively monitor bilirubin concentration by measuring the forehead, anterior chest wall, left and right cheeks and other parts of the newborn. Compared with the invasive detection method of blood drawing to measure serum bilirubin, it is widely used in medical institutions because of its simple and non-invasive measurement process. The measurement results of the jaundice meter can directly reflect the severity of jaundice. In many medical institutions, its measurement results will be used as the basis for monitoring and treatment, and are an important indicator for determining subsequent treatment plans. Therefore, the accuracy of its measurement results is the focus of medical staff.

[0004] At present, the calibration of the indication error of jaundice meters mainly adopts two methods: yellow calibration piece and diluted serum total bilirubin standard material. Both methods only consider the simulation of bilirubin, and do not consider the influence of factors such as melanin, hemoglobin, and skin scattering in the skin. However, the measurement model of the actual jaundice meter has included these influencing factors during research and development and design. Utility Model Content

[0005] In order to overcome the above-mentioned deficiencies of the prior art, the purpose of the utility model is to provide a skin phantom and a mold for calibrating a transcutaneous jaundice detector.

[0006] In order to achieve the above-mentioned purpose, the technical solution adopted by the utility model to solve its technical problems is: a skin phantom for calibrating a transcutaneous jaundice detector, comprising a first simulation layer and a second simulation layer; the first simulation layer is used to simulate the epidermis, the first simulation layer is made of silicone, and a plurality of black material particles are embedded in the first simulation layer; the second simulation layer is used to simulate the dermis and subcutaneous tissue layer, the second simulation layer is made of silicone, and a concave branch-like blood vessel simulation channel is provided on the upper surface of the second simulation layer, and the blood vessel simulation channel is filled with simulated blood with a corresponding bilirubin concentration; a plurality of white scattering particles are embedded in the first simulation layer and the second simulation layer.

[0007] The technical solution of the utility model is adopted, the epidermis is simulated by the first simulation layer, the dermis and subcutaneous tissue are simulated by the second simulation layer containing the vascular simulation channel, the black matter particles in the first simulation layer can simulate melanin, the simulated blood with the nominal bilirubin concentration is injected into the vascular simulation channel, and the simulated blood corresponding to the nominal bilirubin concentration value of the skin phantom is injected into the vascular simulation channel of the skin phantom with different nominal values. The skin phantom of the utility model is used to calibrate the transcutaneous jaundice detector, which comprehensively considers factors such as melanin, blood, and skin scattering in the skin, and improves the accuracy of the calibration measurement of the jaundice instrument.

[0008] Furthermore, the total volume of the black material particles accounts for 0.13% of the total volume of the first simulation layer.

[0009] Furthermore, the thickness of the first simulation layer is 0.1-0.3 mm.

[0010] Furthermore, the thickness of the second simulation layer is 3-3.5 mm.

[0011] Furthermore, the thickness of the blood vessel simulation channel is 0.1 mm.

[0012] By adopting the above preferred solution, the skin phantom is made closer to the characteristics of human skin, and the calibration accuracy of the transcutaneous jaundice detector is improved.

[0013] A mold, comprising an upper cover plate, a side plate, a first base and a second base, wherein the lower surface of the upper cover plate has a protruding portion protruding downward, and the outer edge of the edge of the protruding portion is provided with a plurality of overflow glue ports, the surface of the first base has a first groove with an opening on one side, and the surface of the second base has a second groove with an opening on one side, the first groove and the second groove both match the contour of the protruding portion of the upper cover plate, the bottom surface of the first groove is a plane, and the bottom surface of the second groove has a branch-shaped protrusion, the upper part of the side wall of the first base is provided with a first overflow glue port connected to the first groove, and the upper part of the side wall of the second base is provided with a second overflow glue port connected to the second groove, and the side plate is located at the lateral opening of the first base or the second base;

[0014] The upper cover plate, the side plate and the first base are combined to form a chamber for manufacturing the first simulation layer;

[0015] The upper cover plate, the side plate and the second base are combined to form a chamber for manufacturing the second simulation layer.

[0016] By adopting the technical scheme of the utility model, when making the first simulation layer, the side plate is installed at the lateral opening of the first base, and a proper amount of silica gel mixed with black material particles is injected into the first groove, the upper cover plate is closed, and the upper cover plate is placed in an oven for heating to solidify, and the upper cover plate and the side plate are taken out, and the first simulation layer can be taken out from the lateral opening of the first base. When making the second simulation layer, the side plate is installed at the lateral opening of the second base, and a proper amount of silica gel is injected into the second groove, the upper cover plate is closed, and the upper cover plate is placed in an oven for heating to solidify, and the upper cover plate and the side plate are taken out, and the second simulation layer can be taken out from the lateral opening of the second base. The first simulation layer and the second simulation layer are bonded, and then the simulated blood corresponding to the nominal bilirubin concentration value of the skin phantom is sucked through a needle tube, and it is injected into the blood vessel simulation channel between the first simulation layer and the second simulation layer, and finally the skin phantom is placed in a packaging box, and its bilirubin concentration is measured using a jaundice meter. The skin phantom is made by using this mold, which is convenient and quick to make, and the formed product has high structural stability.

[0017] Furthermore, slots are provided below the lateral openings of the first base and the second base, and the side panels are provided with mating portions matching the slots.

[0018] The above preferred solution is adopted to facilitate the installation of the side panels. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0020] Figure 1 The utility model is a schematic structural diagram of a skin phantom used for calibrating a transcutaneous jaundice detector.

[0021] Figure 2 An exploded view of the mold used to create the first simulation layer.

[0022] Figure 3 An exploded view of the mold used to create the second simulation layer.

[0023] Figure 4 It is a structural schematic diagram of the upper cover.

[0024] Figure 5 It is a structural diagram of the side panel.

[0025] The numbers and letters in the figure represent the names of the corresponding parts:

[0026] 11-first simulation layer; 12-second simulation layer; 13-blood vessel simulation channel; 21-upper cover; 211-protrusion; 212-overflow glue outlet; 22-side panel; 221-mating part; 23-first base; 231-first groove; 232-first overflow glue outlet; 233-slot; 24-second base; 241-second groove; 242-branch-shaped protrusion; 243-second overflow glue outlet. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0028] like Figure 1 One embodiment of the utility model is: a skin phantom for calibrating a transcutaneous jaundice detector, comprising a first simulation layer 11 and a second simulation layer 12, wherein the first simulation layer 11 covers the upper surface of the second simulation layer 12; the first simulation layer 11 is used to simulate the epidermis layer, the first simulation layer 11 is made of silicone material, and a plurality of black material particles are arranged in the first simulation layer 11; the second simulation layer 12 is used to simulate the dermis layer and the subcutaneous tissue layer, and the second simulation layer 12 is made of silicone material; a concave branch-shaped vascular simulation channel 13 is arranged on the upper surface of the second simulation layer 12, and the vascular simulation channel 13 is filled with simulated blood corresponding to the nominal bilirubin concentration value of the skin phantom; a plurality of white scattering particles are embedded in the first simulation layer 11 and the second simulation layer 12.

[0029] The beneficial effects of the above technical solution are: the epidermis is simulated by the first simulation layer, the dermis and subcutaneous tissue are simulated by the second simulation layer containing the vascular simulation channel, the black matter particles in the first simulation layer can simulate melanin, and the simulated blood corresponding to the nominal bilirubin concentration value of the skin phantom is injected into the vascular simulation channel. The skin phantom of the utility model is used to calibrate the transcutaneous jaundice detector, which comprehensively considers factors such as melanin, blood, and skin scattering in the skin, and improves the accuracy of the calibration measurement of the jaundice instrument.

[0030] In some other embodiments of the present invention, the white scattering particles are titanium dioxide particles. The total weight of titanium dioxide in the first simulation layer 11 accounts for 0.1%, and the total weight of titanium dioxide in the second simulation layer 12 accounts for 0.1%.

[0031] In some other embodiments of the present invention, the total volume of the black material particles accounts for 0.13% of the total volume of the first simulation layer 11. The black material particles can be graphite particles.

[0032] In some other embodiments of the present invention, the thickness of the first simulation layer 11 is 0.1-0.3 mm.

[0033] In some other embodiments of the present invention, the thickness of the second simulation layer 12 is 3-3.5 mm.

[0034] In other embodiments of the present invention, the thickness of the blood vessel simulation channel 13 is 0.1 mm.

[0035] The beneficial effects of adopting the above technical solution are: making the skin phantom closer to the characteristics of human skin and improving the accuracy of the calibration of the transcutaneous jaundice detector.

[0036] like Figure 2-5 As shown, a mold comprises an upper cover plate 21, a side plate 22, a first base 23 and a second base 24. The lower surface of the upper cover plate 21 has a protruding portion 211 protruding downward, and the outer edge of the edge of the protruding portion 211 is provided with a plurality of overflow glue ports 212. The surface of the first base 23 has a first groove 231 with an opening on one side, and the surface of the second base 24 has a second groove 241 with an opening on one side. The first groove 231 and the second groove 241 both match the contour of the protruding portion 211 of the upper cover plate. The bottom surface of the first groove 231 is a plane, and the bottom surface of the second groove 241 has a branch-shaped protrusion 242. The upper part of the side wall of the first base 23 is provided with a first overflow glue port 232 communicating with the first groove 231, and the upper part of the side wall of the second base 24 is provided with a second overflow glue port 243 communicating with the second groove 241. The side plate 22 is located at the lateral opening of the first base 23 or the second base 24.

[0037] The upper cover plate 21, the side plate 22 and the first base 23 are combined to form a chamber for manufacturing the first simulation layer 11;

[0038] The upper cover plate 21 , the side plate 22 and the second base 24 are combined to form a chamber for manufacturing the second simulation layer 12 .

[0039] The beneficial effects of the above technical solution are as follows: when making the first simulation layer, the side plate is installed at the lateral opening of the first base, and a proper amount of silica gel mixed with black material particles is injected into the first groove, the upper cover is closed, and it is placed in an oven for heating to solidify, and the upper cover and the side plate are taken out, and the first simulation layer can be taken out from the lateral opening of the first base. When making the second simulation layer, the side plate is installed at the lateral opening of the second base, and a proper amount of silica gel is injected into the second groove, the upper cover is closed, and it is placed in an oven for heating to solidify, and the upper cover and the side plate are taken out, and the second simulation layer can be taken out from the lateral opening of the second base. The first simulation layer and the second simulation layer are bonded, and then the simulated blood corresponding to the nominal bilirubin concentration value of the skin phantom is sucked through a needle tube, and it is injected into the blood vessel simulation channel between the first simulation layer and the second simulation layer, and finally the skin phantom is placed in a packaging box, and its bilirubin concentration is measured using a jaundice meter. The production is convenient and quick.

[0040] like Figure 2 , 5 As shown, in some other embodiments of the present invention, a slot 233 is provided below the lateral opening of the first base 23, and a mating portion 221 matching the slot 233 is provided on the side panel 22. The beneficial effect of adopting the above technical solution is that it is convenient to install the side panel on the first base and the second base.

[0041] The above embodiments are only for illustrating the technical concept and features of the utility model, and their purpose is to enable ordinary technicians in the field to understand the content of the utility model and implement it. They cannot be used to limit the protection scope of the utility model. All equivalent changes or modifications made according to the spirit of the utility model should be included in the protection scope of the utility model.

Claims

1. A skin phantom for calibrating a transcutaneous jaundice detector, characterized in that: It includes a first simulation layer and a second simulation layer; the first simulation layer is used to simulate the epidermis layer, the first simulation layer is made of silicone, and a plurality of black material particles are embedded in the first simulation layer; the second simulation layer is used to simulate the dermis layer and the subcutaneous tissue layer, the second simulation layer is made of silicone, and a concave branch-shaped blood vessel simulation channel is provided on the upper surface of the second simulation layer, and the blood vessel simulation channel is filled with simulated blood corresponding to the nominal bilirubin concentration value of the skin phantom; a plurality of white scattering particles are embedded in the first simulation layer and the second simulation layer.

2. The skin phantom for calibrating a transcutaneous jaundice detector according to claim 1, characterized in that: The total volume of the black substance particles accounts for 0.13% of the total volume of the first simulation layer.

3. The skin phantom for calibrating a transcutaneous jaundice detector according to claim 1, characterized in that: The thickness of the first simulation layer is 0.1-0.3 mm.

4. The skin phantom for calibrating a transcutaneous jaundice detector according to claim 3, characterized in that: The thickness of the second simulation layer is 3-3.5 mm.

5. The skin phantom for calibrating a transcutaneous jaundice detector according to claim 4, characterized in that: The thickness of the blood vessel simulation channel is 0.1 mm.

6. A mold, characterized in that: Used to manufacture the skin phantom for calibrating a transcutaneous jaundice detector as claimed in claim 1, comprising an upper cover plate, a side plate, a first base and a second base, the lower surface of the upper cover plate having a protruding portion protruding downward, the outer edge of the edge of the protruding portion is provided with a plurality of overflow glue ports, the surface of the first base has a first groove with an opening on one side, the surface of the second base has a second groove with an opening on one side, the first groove and the second groove both match the contour of the protruding portion of the upper cover plate, the bottom surface of the first groove is a plane, the bottom surface of the second groove has a branch-shaped protrusion, the upper part of the side wall of the first base is provided with a first overflow glue port connected to the first groove, the upper part of the side wall of the second base is provided with a second overflow glue port connected to the second groove, and the side plate is located at the lateral opening of the first base or the second base; The upper cover plate, the side plate and the first base are combined to form a chamber for manufacturing the first simulation layer; The upper cover plate, the side plate and the second base are combined to form a chamber for manufacturing the second simulation layer.

7. The mold according to claim 6, characterized in that: Slots are provided below the lateral openings of the first base and the second base, and the side panels are provided with mating parts matching the slots.

Images