Solid-liquid separation equipment for biological pharmacy

By designing solid-liquid separation adjustment mechanism and auxiliary connection mechanism in solid-liquid separation equipment for biopharmaceuticals, the problem of compression deformation of the filter mesh and difficulty in disassembly and cleaning of the extrusion plate during the drug extrusion process is solved, achieving more efficient solid-liquid separation and more convenient equipment maintenance.

CN222697986UActive Publication Date: 2025-04-01ZHEJIANG HISUN PHARMA CO LTD
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Patent Information

Application Number
CN202421376087.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-17
Publication Date
2025-04-01
Estimated Expiration
2034-06-17

AI Technical Summary

Technical Problem

The existing solid-liquid separation equipment for biopharmaceuticals can easily lead to compression and deformation of the filter screen during the drug extrusion process, and the extrusion pressure is difficult to achieve the effect of solid-liquid separation, and the extrusion plate is difficult to disassemble, clean and quickly replace.

Method used

A solid-liquid separation device for biopharmaceuticals including a solid-liquid separation adjustment mechanism and an auxiliary connection mechanism is designed. The solid-liquid separation adjustment mechanism extrudes the drug through an electric cylinder drives the pressure plate and is equipped with a support assembly to support the filter to ensure the extrusion effect. The platen replacement assembly allows quick removal and replacement of the platen. The auxiliary connection mechanism facilitates the rapid installation and removal of the liquid storage barrel.

Benefits of technology

It improves the efficiency of drug extrusion and the effect of solid-liquid separation, simplifies the replacement and cleaning process of the press plate, and improves the convenience and maintenance of the equipment.

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Abstract

The utility model relates to the technical field of biopharmacy solid-liquid separation, and discloses biopharmacy solid-liquid separation equipment which comprises a fixed seat, a connecting frame fixedly mounted at the top of the fixed seat, a filter screen inserted and mounted in the connecting frame, and an electric cylinder fixedly mounted at the top of the connecting frame, a solid-liquid separation adjusting mechanism is arranged at the output end of the electric air cylinder and in the connecting frame, a liquid outlet pipe is arranged outside the connecting frame and the solid-liquid separation adjusting mechanism, a liquid storage barrel is arranged in the fixing base, and an auxiliary connecting mechanism is arranged between the liquid outlet pipe and the liquid storage barrel. According to the solid-liquid separation equipment for biological pharmacy, in the using process, medicine can be extruded by arranging a solid-liquid separation adjusting mechanism, under the action of a supporting plate, the extruding effect on the medicine can be guaranteed, a first pressing plate can be rapidly disassembled, and by arranging an auxiliary connecting mechanism, in the using process, the medicine can be conveniently and rapidly separated; and the liquid outlet pipe and the liquid storage barrel can be quickly assembled and disassembled.
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Description

Technical Field

[0001] The utility model relates to the technical field of biopharmaceutical solid-liquid separation, in particular to a biopharmaceutical solid-liquid separation device. Background Art

[0002] Biopharmaceuticals refer to a type of products used for prevention, treatment and diagnosis that are manufactured by applying research results in biology, medicine and other fields, and integrating scientific principles and methods such as biochemistry and pharmacy. In production, they often require the use of special solid-liquid separation equipment for solid-liquid separation.

[0003] According to the description of a biopharmaceutical solid-liquid separation device disclosed on the patent website (authorization announcement number: CN214232960U), "The utility model belongs to the field of biopharmaceutical technology, and is particularly a biopharmaceutical solid-liquid separation device, including a separator, a first hinge and a control box. An electric lifting sleeve is provided inside the separator, and an extrusion plate is provided below the electric lifting sleeve, a rubber pad is provided below the extrusion plate, and a fixing bolt is provided below the rubber pad, a slide is provided below the fixing bolt, and a slider is provided inside the slide, a support plate is provided on one side of the slider, and a slot is provided on one side of the support plate, a block is provided inside the slot, and a filter screen is provided on one side of the block, a slide rail is provided below the filter screen, and pulleys are provided inside the slide rails. The solid-liquid separation device for biopharmaceuticals can easily clean the solid residue above the filter screen, and the liquid will flow into the drawer through the filter screen, and then the drawer is pulled outward, so that the pulley drives the drawer to move outward, and the liquid can be collected and cleaned."

[0004] In view of the above description, the applicant believes that there are the following problems:

[0005] During use, the utility model can clean the solid residue above the filter screen, and the liquid will flow into the drawer through the filter screen. The drawer is then pulled outward, so that the pulley drives the drawer to move outward, and the liquid can be collected and cleaned. However, in actual applications, when the device extrude the medicine, it only extrude the medicine on the surface of the filter screen through the provided extrusion plate. The filter screen is easily compressed and deformed during the extrusion process, resulting in the extrusion force being difficult to achieve the effect of solid-liquid separation. Moreover, since the position of the extrusion plate of the device is relatively fixed, it is difficult to disassemble and clean the extrusion plate. As the extrusion work continues, when the extrusion plate is worn, it is difficult to quickly replace it. Therefore, we urgently need to improve a solid-liquid separation device for biopharmaceuticals to solve the above problems. Utility Model Content

[0006] The purpose of the utility model is to provide a solid-liquid separation device for biopharmaceuticals to solve the problems raised in the above background technology.

[0007] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a solid-liquid separation device for biopharmaceuticals, comprising a fixed seat, a connecting frame fixedly installed on the top of the fixed seat, a filter screen inserted and installed inside the connecting frame, an electric cylinder fixedly installed on the top of the connecting frame, a solid-liquid separation regulating mechanism is arranged at the output end of the electric cylinder and inside the connecting frame, a liquid outlet pipe is arranged outside the connecting frame and the solid-liquid separation regulating mechanism, a liquid storage barrel is arranged inside the fixed seat, and an auxiliary connecting mechanism is arranged between the liquid outlet pipe and the liquid storage barrel.

[0008] The solid-liquid separation regulating mechanism comprises a pressure plate replacement assembly and a support assembly, and the pressure plate replacement assembly is arranged on the top of the support assembly.

[0009] Preferably, the pressure plate replacement assembly includes a mounting plate and an adjusting plate, the mounting plate is fixedly installed on the output end of the electric cylinder, a connecting frame is fixedly installed on the bottom of the mounting plate, a first plug-in block is arranged on the right side of the adjusting plate, a second plug-in block is slidably installed inside the left side of the adjusting plate, a first spring is arranged inside the adjusting plate, a first connecting plate is fixedly installed on the bottom of the second plug-in block, and a first pressure plate is fixedly installed on the bottom of the adjusting plate, which is convenient for squeezing the medicine and can be quickly disassembled when the first pressure plate needs to be replaced or cleaned.

[0010] Preferably, an installation groove is opened inside the adjustment plate at a position corresponding to the second plug-in block, the first spring is fixedly installed with the second plug-in block near one side of the second plug-in block, and the first plug-in block, the second plug-in block and the connecting frame are plug-connected and installed, which facilitates quick installation and disassembly of the first pressure plate.

[0011] Preferably, the support assembly includes a mounting frame and a support plate, the mounting frame is fixedly installed on the bottom end of the connecting frame, a bidirectional screw is rotatably installed inside the mounting frame, a handle is fixedly installed on the right side of the bidirectional screw, a limit rod is fixedly installed inside the mounting frame, a movable block is threadedly installed on the outside of the bidirectional screw, a second connecting plate is rotatably installed on the outside of the movable block, a guide rail is fixedly installed on the bottom of the support plate, and a connecting block is slidably installed on the outside of the guide rail, so that the filter can be supported when the medicine is extruded to ensure the extrusion effect.

[0012] Preferably, through holes are opened at corresponding positions of the movable block and the limit rod, the limit rod passes through the through holes, the second connecting plate is rotatably installed with the connecting block on the side away from the movable block, and the movable block, the second connecting plate and the connecting block are each provided with two groups, so as to facilitate dynamic adjustment of the height of the support plate according to different extrusion requirements.

[0013] Preferably, the auxiliary connecting mechanism includes a fixed column, which is fixedly installed at the bottom of the liquid outlet pipe, a sleeve is slidably installed on the outside of the fixed column, a second spring is fixedly installed inside the fixed column, a locking ball is movably installed inside the fixed column, and a plug-in tube is plug-in installed inside the fixed column, so as to facilitate quick installation and disassembly of the liquid outlet pipe and the liquid storage barrel.

[0014] Preferably, a mounting hole is provided inside the fixing column at a position corresponding to the locking ball, the inside of the sleeve tube abuts against the fixing column, a limiting groove is provided between the fixing column and the sleeve tube, the second spring is arranged inside the limiting groove, the top of the second spring is fixedly installed inside the sleeve tube, the bottom of the second spring is fixedly installed inside the limiting groove, an abutment block is installed inside the sleeve tube at a position corresponding to the locking ball, and the bottom of the plug-in tube is fixedly installed with the liquid storage barrel, so as to facilitate quick installation and disassembly.

[0015] Compared with the prior art, the utility model provides a solid-liquid separation device for biopharmaceuticals, which has the following beneficial effects:

[0016] 1. The solid-liquid separation equipment for biopharmaceuticals is provided with a solid-liquid separation regulating mechanism. During use, the medicine can be squeezed in cooperation with an electric cylinder. With the support of the support plate on the filter screen, the squeezing effect of the medicine can be ensured, the solid-liquid separation effect can be improved, and when the first pressing plate needs to be replaced or cleaned, the first pressing plate can be quickly disassembled.

[0017] 2. The solid-liquid separation equipment for biopharmaceuticals is provided with an auxiliary connection mechanism. During use, when it is necessary to transfer the liquid in the liquid storage barrel, the locking ball and the plug-in tube can be disengaged from the locking state, and then the liquid storage barrel can be taken out. When the liquid storage barrel needs to be assembled, the locking ball and the plug-in tube can be locked to complete the installation, which is convenient for collecting the liquid. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative labor:

[0019] Figure 1 This is a schematic diagram of the appearance structure of the utility model;

[0020] Figure 2 It is a right side structural schematic diagram of the utility model;

[0021] Figure 3 This is a schematic diagram of the internal structure of the utility model;

[0022] Figure 4 This is a schematic diagram of the disassembled structure of the pressure plate replacement assembly of the utility model;

[0023] Figure 5 This is a schematic diagram of the disassembled structure of the support assembly of the utility model;

[0024] Figure 6 This is a schematic diagram of the disassembled structure of the auxiliary connecting mechanism of the utility model.

[0025] In the figure: 1. fixing seat; 2. connecting frame; 3. filter screen; 4. electric cylinder; 5. solid-liquid separation adjustment mechanism; 51. pressure plate replacement assembly; 511. mounting plate; 512. connecting frame; 513. adjustment plate; 514. first plug-in block; 515. second plug-in block; 516. first spring; 517. first connecting plate; 518. first pressure plate; 52. support assembly; 521. mounting frame; 522. bidirectional screw; 523. handle; 524. limit rod; 525. movable block; 526. second connecting plate; 527. supporting plate; 528. guide rail; 529. connecting block; 6. liquid outlet pipe; 7. liquid storage barrel; 8. auxiliary connecting mechanism; 81. fixing column; 82. socket tube; 83. second spring; 84. locking ball; 85. plug-in tube. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0027] In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0028] Embodiment 1:

[0029] See also Figure 1-5The utility model provides a technical solution: a solid-liquid separation device for biopharmaceuticals, comprising a fixed seat 1, a connecting frame 2 is fixedly installed on the top of the fixed seat 1, a filter screen 3 is plugged and installed inside the connecting frame 2, an electric cylinder 4 is fixedly installed on the top of the connecting frame 2, a solid-liquid separation regulating mechanism 5 is arranged at the output end of the electric cylinder 4 and inside the connecting frame 2, a liquid outlet pipe 6 is arranged outside the connecting frame 2 and the solid-liquid separation regulating mechanism 5, a liquid storage barrel 7 is arranged inside the fixed seat 1, and an auxiliary connecting mechanism 8 is arranged between the liquid outlet pipe 6 and the liquid storage barrel 7.

[0030] The solid-liquid separation regulating mechanism 5 comprises a pressure plate replacement assembly 51 and a support assembly 52 , and the pressure plate replacement assembly 51 is arranged on the top of the support assembly 52 .

[0031] Furthermore, the pressure plate replacement assembly 51 includes a mounting plate 511 and an adjusting plate 513. The mounting plate 511 is fixedly installed at the output end of the electric cylinder 4. A connecting frame 512 is fixedly installed at the bottom of the mounting plate 511. A first plug-in block 514 is arranged on the right side of the adjusting plate 513. A second plug-in block 515 is slidingly installed inside the left side of the adjusting plate 513. A first spring 516 is arranged inside the adjusting plate 513. A first connecting plate 517 is fixedly installed at the bottom of the second plug-in block 515. A first pressure plate 518 is fixedly installed at the bottom of the adjusting plate 513 to facilitate the extrusion of the drug. When the first pressure plate 518 needs to be replaced or cleaned, the first pressure plate 518 can be quickly disassembled.

[0032] Furthermore, an installation groove is opened inside the adjustment plate 513 at a position corresponding to the second plug-in block 515, and the first spring 516 is fixedly installed with the second plug-in block 515 near one side of the second plug-in block 515. The first plug-in block 514 and the second plug-in block 515 are plugged and installed with the connecting frame 512, which facilitates the quick installation and disassembly of the first pressure plate 518.

[0033] Furthermore, the support assembly 52 includes a mounting frame 521 and a support plate 527. The mounting frame 521 is fixedly installed at the bottom end of the connecting frame 2. A bidirectional screw 522 is rotatably installed inside the mounting frame 521. A handle 523 is fixedly installed on the right side of the bidirectional screw 522. A limit rod 524 is fixedly installed inside the mounting frame 521. A movable block 525 is threadedly installed on the outside of the bidirectional screw 522. A second connecting plate 526 is rotatably installed on the outside of the movable block 525. A guide rail 528 is fixedly installed on the bottom of the support plate 527. A connecting block 529 is slidably installed on the outside of the guide rail 528, so that the filter screen 3 can be supported when the medicine is extruded to ensure the extrusion effect.

[0034] Furthermore, through holes are opened at corresponding positions of the movable block 525 and the limiting rod 524, and the limiting rod 524 passes through the through holes. The second connecting plate 526 is rotatably installed with the connecting block 529 on the side away from the movable block 525. The movable block 525, the second connecting plate 526, and the connecting block 529 are each provided with two groups, so as to facilitate dynamic adjustment of the height of the support plate 527 according to different extrusion requirements.

[0035] Embodiment 2:

[0036] See also Figure 6 In combination with the first embodiment, it is further obtained that the auxiliary connection mechanism 8 includes a fixed column 81, the fixed column 81 is fixedly installed at the bottom of the liquid outlet pipe 6, a sleeve 82 is slidably installed on the outside of the fixed column 81, a second spring 83 is fixedly installed inside the fixed column 81, a locking ball 84 is movably installed inside the fixed column 81, and a plug-in tube 85 is plug-in installed inside the fixed column 81, which is convenient for quick installation and disassembly of the liquid outlet pipe 6 and the liquid storage barrel 7.

[0037] Furthermore, a mounting hole is provided inside the fixing column 81 at a position corresponding to the locking ball 84, the inside of the sleeve tube 82 abuts against the fixing column 81, a limiting groove is provided between the fixing column 81 and the sleeve tube 82, the second spring 83 is arranged inside the limiting groove, the top of the second spring 83 is fixedly installed inside the sleeve tube 82, the bottom of the second spring 83 is fixedly installed inside the limiting groove, an abutment block is installed inside the sleeve tube 82 at a position corresponding to the locking ball 84, and the bottom of the plug-in tube 85 is fixedly installed on the liquid storage barrel 7, so as to achieve a quick installation and disassembly effect.

[0038] In actual operation, when the device is used, when it is necessary to separate the medicine into solid and liquid, the medicine to be separated into solid and liquid can be placed inside the filter 3. In order to ensure that the medicine is fully squeezed and the filter 3 is prevented from being deformed by compression during the squeezing process, the handle 523 can be turned to rotate the bidirectional screw 522. Under the action of the limit rod 524, the two sets of movable blocks 525 can be moved in a centering manner, so that the second connecting plate 526 is rotated, so that the connecting block 529 is slid outside the guide rail 528, so that the height of the support plate 527 changes, so that the support plate 527 is aligned with the bottom of the filter 3. After the contact is completed, the electric cylinder 4 can be opened to drive the first pressing plate 518 to squeeze the medicine inside the filter screen 3. Under the support of the support plate 527, the squeezing effect of the medicine can be guaranteed and the solid-liquid separation effect can be improved. The liquid generated during squeezing will flow into the liquid storage barrel 7 through the liquid outlet pipe 6 for storage. After the squeezing is completed, the electric cylinder 4 can be controlled to make the first pressing plate 518 and the filter screen 3 out of the squeezing state, and then the medicine residue inside the filter screen 3 can be cleaned. When the first pressing plate 518 needs to be replaced or cleaned, the first connecting plate 517 can be pulled to make the second plug-in block 515 inside the adjusting plate 513 The first plug-in block 514 is then connected to the connecting frame 512 and the first connecting plate 517 is then pulled to retract the second plug-in block 515 into the adjusting plate 513. When the second plug-in block 515 is opposite to the connecting frame 512, the first connecting plate 517 is released, and the first spring 516 is used to rebound. The second plug-in block 515 is plugged into the connecting frame 512 to complete the installation of the first pressure plate 518. When the liquid in the liquid storage barrel 7 needs to be transferred, the sleeve 82 can be pulled to disengage the locking ball 84 and the plug-in tube 85 from the locked state, and then the liquid storage barrel 7 can be taken out. When the liquid storage barrel 7 needs to be assembled, the sleeve 82 can be slid upward, and then the plug-in tube 85 can be plugged into the inside of the fixed column 81, and the sleeve 82 is loosened. Under the action of the second spring 83, the sleeve 82 will return to its initial position, and the abutment block will lock the locking ball 84 and the plug-in tube 85 to complete the installation, which is convenient for collecting liquid.

[0039] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the statement "comprise a ..." do not exclude the presence of other identical elements in the process, method, article or device including the elements.

Claims

1. A solid-liquid separation device for biopharmaceuticals, comprising a fixing seat (1), characterized in that: A connecting frame (2) is fixedly mounted on the top of the fixing seat (1), a filter screen (3) is plugged and mounted inside the connecting frame (2), an electric cylinder (4) is fixedly mounted on the top of the connecting frame (2), a solid-liquid separation regulating mechanism (5) is arranged at the output end of the electric cylinder (4) and inside the connecting frame (2), a liquid outlet pipe (6) is arranged outside the connecting frame (2) and the solid-liquid separation regulating mechanism (5), a liquid storage barrel (7) is arranged inside the fixing seat (1), and an auxiliary connecting mechanism (8) is arranged between the liquid outlet pipe (6) and the liquid storage barrel (7); The solid-liquid separation regulating mechanism (5) comprises a pressure plate replacement assembly (51) and a support assembly (52), wherein the pressure plate replacement assembly (51) is arranged on the top of the support assembly (52).

2. A biopharmaceutical solid-liquid separation device according to claim 1, characterized in that: The pressure plate replacement assembly (51) comprises a mounting plate (511) and an adjustment plate (513); the mounting plate (511) is fixedly mounted on the output end of the electric cylinder (4); a connecting frame (512) is fixedly mounted on the bottom of the mounting plate (511); a first plug-in block (514) is arranged on the right side of the adjustment plate (513); a second plug-in block (515) is slidably mounted inside the left side of the adjustment plate (513); a first spring (516) is arranged inside the adjustment plate (513); a first connecting plate (517) is fixedly mounted on the bottom of the second plug-in block (515); and a first pressure plate (518) is fixedly mounted on the bottom of the adjustment plate (513).

3. A biopharmaceutical solid-liquid separation device according to claim 2, characterized in that: An installation groove is provided inside the adjustment plate (513) at a position corresponding to the second plug-in block (515); the first spring (516) is fixedly installed with the second plug-in block (515) at a side close to the second plug-in block (515); and the first plug-in block (514) and the second plug-in block (515) are plug-connected and installed with the connection frame (512).

4. The solid-liquid separation device for biopharmaceuticals according to claim 1, characterized in that: The support assembly (52) comprises a mounting frame (521) and a support plate (527). The mounting frame (521) is fixedly mounted on the bottom end of the connecting frame (2). A bidirectional screw rod (522) is rotatably mounted inside the mounting frame (521). A handle (523) is fixedly mounted on the right side of the bidirectional screw rod (522). A limit rod (524) is fixedly mounted inside the mounting frame (521). A movable block (525) is threadedly mounted on the outside of the bidirectional screw rod (522). A second connecting plate (526) is rotatably mounted on the outside of the movable block (525). A guide rail (528) is fixedly mounted on the bottom of the support plate (527). A connecting block (529) is slidably mounted on the outside of the guide rail (528).

5. A biopharmaceutical solid-liquid separation device according to claim 4, characterized in that: Through holes are provided at corresponding positions of the movable block (525) and the limiting rod (524), and the limiting rod (524) passes through the through holes. The second connecting plate (526) is rotatably mounted on the connecting block (529) at a side away from the movable block (525). The movable block (525), the second connecting plate (526), ​​and the connecting block (529) are each provided in two groups.

6. The solid-liquid separation device for biopharmaceuticals according to claim 1, characterized in that: The auxiliary connection mechanism (8) comprises a fixed column (81), the fixed column (81) is fixedly installed at the bottom of the liquid outlet pipe (6), a sleeve tube (82) is slidably installed on the outside of the fixed column (81), a second spring (83) is fixedly installed inside the fixed column (81), a locking ball (84) is movably installed inside the fixed column (81), and a plug-in tube (85) is plug-in installed inside the fixed column (81).

7. The solid-liquid separation device for biopharmaceuticals according to claim 6, characterized in that: A mounting hole is provided inside the fixing column (81) at a position corresponding to the locking ball (84); the inside of the sleeve tube (82) is in contact with the fixing column (81); a limiting groove is provided between the fixing column (81) and the sleeve tube (82); the second spring (83) is arranged inside the limiting groove; the top of the second spring (83) is fixedly installed inside the sleeve tube (82); the bottom of the second spring (83) is fixedly installed inside the limiting groove; an abutment block is installed inside the sleeve tube (82) at a position corresponding to the locking ball (84); and the bottom of the plug-in tube (85) is fixedly installed with the liquid storage barrel (7).

Citation Information

Patent Citations

  • Solid-liquid separation equipment for biological pharmacy

    CN214232960U